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<|newrecord|> nctId: NCT06332781 id: 2126175 briefTitle: Intravesical Gentamicin to Prevent Recurrent UTI overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2025-06-01 date: 2025-07-31 date: 2024-03-27 date: 2024-03-28 name: Women and Infants Hospital of Rhode Island class: OTHER briefSummary: Feasibility assessm... |
<|newrecord|> nctId: NCT06332768 id: WEAN_2021 briefTitle: NIV Versus HFO Versus Standard Therapy Immediately After Weaning From Mechanical Ventilation in ARDS Patients overallStatus: COMPLETED date: 2017-09-01 date: 2022-01-01 date: 2022-03-01 date: 2024-03-27 date: 2024-03-27 name: Northern State Medical University c... |
<|newrecord|> nctId: NCT06332755 id: LG-LRCL001 briefTitle: Study to Evaluate LB-LR1109 for the Treatment of Solid Tumors acronym: LB-LR1109 overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-11 date: 2027-02 date: 2024-03-27 date: 2024-03-27 name: LG Chem class: INDUSTRY briefSummary: This is a Phase 1, first-... |
<|newrecord|> nctId: NCT06332742 id: QXZS for DOR briefTitle: Real-world Evaluation of Qingxin Zishen Decoction on Ovarian Reserve Function Clinical Efficacy in Patients With Decreased overallStatus: RECRUITING date: 2023-11-01 date: 2026-12-31 date: 2026-12-31 date: 2024-03-27 date: 2024-04-04 name: Yun Chen class: OT... |
<|newrecord|> nctId: NCT06332729 id: EG,KFS,lab reserach 6 briefTitle: Universal Exercise Unit Versus Functional Electrical Stimulation On Genu Recurvatum In Diplegic Cerebral Palsy overallStatus: RECRUITING date: 2024-02-01 date: 2024-05-15 date: 2024-06-15 date: 2024-03-27 date: 2024-03-27 name: Mahmoud Reda Elsharka... |
Inclusion Criteria: |
* Children aged four to eight years. |
* Grade of spasticity ranging from 1 to 1+ on the Modified Ashworth scale. |
* Classified as Level I or II on the Gross Motor Functional Classification System (GMFCS). |
* Ability to follow verbal commands and instructions. |
Exclusion Criteria: |
* Previous neurological or orthopedic surgery in the lower extremities. |
* Botox injection in the lower extremities within the past six months. |
* Fixed deformity in the joints of the lower limb. |
* Genu recarvatum secondary to surgery. |
* Severe hearing and visual defects. |
Materials for Subject Selection and Evaluation: |
* Modified Ashworth Scale for muscle tone assessment. |
* Gross Motor Functional Classification System (GMFCS) for functional activity classification. |
* Digital goniometer for measuring the angle of knee hyperextension. |
* Lafayette Manual Muscle Tester for quantifying muscle strength. |
Methods: |
* Assessment of muscle tone using the Modified Ashworth Scale, evaluating spasticity in calf muscles and hip/knee extensors. |
* Evaluation of gross motor function using the GMFCS. |
* Assessment of genu recarvatum using a digital goniometer. |
* Assessment of muscle strength using the Lafayette Manual Muscle Tester, focusing on hamstrings and tibialis anterior muscles. |
* Assessment of range of motion in the knee joint using Kinovea software. |
* Treatment procedures involving physical therapy sessions with a combination of exercises and interventions tailored to each group (Group A and Group B). |
Group A Treatment: |
- Designed physical therapy program combined with pulley therapy for muscle strengthening. |
Group B Treatment: |
- Designed physical therapy program combined with functional electrical stimulation during walking on a treadmill for muscle stimulation. |
The interventions in both groups aim to improve muscle strength, range of motion, and functional abilities in children with cerebral palsy. conditions: Cerebral Palsy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: PARTICIPANT ... |
<|newrecord|> nctId: NCT06332716 id: KY20222234 briefTitle: Research on the Correlation Between Organoid Drug Sensitivity Testing and Precise Treatment of Gastrointestinal Tumors overallStatus: RECRUITING date: 2022-08-26 date: 2025-12 date: 2025-12 date: 2024-03-27 date: 2024-03-27 name: Jianjun Yang,MD class: OTHER b... |
<|newrecord|> nctId: NCT06332703 id: IACA briefTitle: Acanthamoeba and Artificial Intelligence overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-10 date: 2025-04 date: 2024-03-27 date: 2024-03-27 name: IRCCS Ospedale San Raffaele class: OTHER briefSummary: Acanthamoeba keratitis, caused by the pathogen Acantha... |
This observational retrospective and single-center study, of exploratory nature, aims to determine the possibility of identifying patterns that may be useful for future rapid diagnosis of Acanthamoeba keratitis from confocal images, leveraging the normality of corneal examination and the high specificity and sensitivit... |
The data will be based on patients who have been confirmed positive through laboratory tests with proven effectiveness in detecting the infection. |
The laboratory tests considered for the division of patients into their respective groups are bacterial examination, PCR examination, and culture examination. |
Patients were divided into two groups, the first comprising patients positive for Acanthamoeba infection, while the second comprised patients negative for Acanthamoeba but positive for other pathogens. The study will last for 18 months. |
The cohort under study includes 151 patients from the IRCCS San Raffaele Hospital who underwent the aforementioned examinations, of which 76 cases will be included in the group of patients positive for Acanthamoeba and 75 in the group of controls positive for other pathogens. |
The confocal images of this cohort will be fed into artificial intelligence software. To evaluate the model, the test set will be used, and the AI model's ability will be assessed using the most commonly used metrics in the field of computer vision such as accuracy, specificity, sensitivity, and f1-score; culminating i... |
<|newrecord|> nctId: NCT06332690 id: 514.2021 briefTitle: OCT and OCT-Angiography Biomarkers of Treatment Response to Dexamethasone Implant in Macular Edema Due to Retinal Vascular Diseases - DME and RVO overallStatus: RECRUITING date: 2023-10-17 date: 2025-06 date: 2025-12 date: 2024-03-27 date: 2024-03-27 name: IRCCS... |
<|newrecord|> nctId: NCT06332677 id: TERS briefTitle: Target of Suv420h1/2 in Hepatocytes overallStatus: RECRUITING date: 2023-03-01 date: 2025-02 date: 2026-02 date: 2024-03-27 date: 2024-03-27 name: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico class: OTHER briefSummary: Nonalcoholic fatty liver disease ... |
<|newrecord|> nctId: NCT06332664 id: 2023-2330 briefTitle: Early Nutrition Intervention for M1 Stage Cancer Patients overallStatus: RECRUITING date: 2024-01-01 date: 2025-01-01 date: 2025-07-01 date: 2024-03-27 date: 2024-03-27 name: Xingchen Peng class: OTHER briefSummary: In China, the treatment of advanced-stage can... |
However, symptoms such as appetite loss, weight loss, and anxiety are often overlooked. It is common for clinical nutritionists to passively enter oncology wards to conduct comprehensive nutritional assessments and develop nutrition plans only when patients exhibit significant malnutrition, upon request from oncologist... |
Against this background, the investigators integrated clinical nutritionists into the oncology treatment team and established a proactive nutritional intervention team specifically targeting M1 advanced-stage cancer patients. This initiative aims to conduct a single-center, open-label, randomized parallel-group prospec... |
<|newrecord|> nctId: NCT06332651 id: NL84684.091.23 briefTitle: Metabolic Availability in Older and Younger Men acronym: YOMA overallStatus: RECRUITING date: 2024-02-19 date: 2024-12-31 date: 2025-04-01 date: 2024-03-27 date: 2024-03-27 name: Wageningen University class: OTHER briefSummary: The main goal of this study ... |
<|newrecord|> nctId: NCT06332638 id: IN_APA_124 briefTitle: PK, PD and Safety of Tegoprazan 12.5 mg After Oral Administration in Healthy Subjects overallStatus: ENROLLING_BY_INVITATION date: 2024-03-19 date: 2024-07-31 date: 2024-07-31 date: 2024-03-27 date: 2024-03-27 name: HK inno.N Corporation class: INDUSTRY briefS... |
<|newrecord|> nctId: NCT06332625 id: PNRR-MR1-2022-12375648 briefTitle: The Fingerprinting of Inherited Leukoencephalopathies: A New Brain Imaging, Genetic and Clinical Assessment acronym: FIABA overallStatus: RECRUITING date: 2023-05-22 date: 2024-02-05 date: 2025-11-22 date: 2024-03-27 date: 2024-03-27 name: IRCCS Fo... |
The project's objective is to evaluate and validate new and innovative quantitative magnetic resonance imaging (qMRI) methodologies at both clinical and ultra-high fields in inherited leukodystrophies and those of unknown etiology. |
This is a national, multi-institutional, multicenter exploratory study on the potential identification and predictability of early structural and metabolic markers in quantitative MRI at 3T and 7T in the diagnosis and follow-up of leukodystrophy and leukoencephalopathy in adults and during development. |
The study will include multiple sub-studies: |
1. A cross-sectional study in leukoencephalopathies at clinical fields. |
2. A longitudinal study in leukoencephalopathies at 3T: natural history and therapy outcomes. |
3. A cross-sectional and longitudinal study at 7T: The added value of ultra-high-field Magnetic Resonance Imaging in leukoencephalopathies. conditions: Leukoencephalopathies studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: Brain quantitative magnetic reso... |
<|newrecord|> nctId: NCT06332612 id: 8420224AROM briefTitle: Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial acronym: MROSF overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-09 date: 2024-12 date: 2024-03-27 date: 2024-03-27 name: Ziauddin ... |
Groups: |
* Metformin-treated |
* Control (untreated) |
* Vehicle control Clinical Trial Study Design: A pilot Randomized Controlled Trial (RCT) translating the in vitro findings into a clinical setting. It would be a single-blind, placebo-controlled designAll groups will undergo a 24-week intervention phase. Group 1 will receive standard treatment including topical cream b... |
<|newrecord|> nctId: NCT06332599 id: rjhy20240001 briefTitle: Minocycline for Helicobacter Pylori Rescue Treatment overallStatus: RECRUITING date: 2021-10-01 date: 2024-04-30 date: 2034-06-30 date: 2024-03-27 date: 2024-03-27 name: Shanghai Jiao Tong University School of Medicine class: OTHER briefSummary: Current guid... |
<|newrecord|> nctId: NCT06332586 id: 202311087RINA briefTitle: The Learning Effect of Applying Diversified Teaching in Emergency Injury Classification -Taking the Emergency Nurse of a Regional Hospital in Yunlin County as an Example overallStatus: ENROLLING_BY_INVITATION date: 2024-03-25 date: 2024-04-04 date: 2024-05-... |
<|newrecord|> nctId: NCT06332573 id: 24-06 briefTitle: Impact of Onco-sexology Support on the Quality of Life of Patients Newly Diagnosed for Cancer acronym: SEXOCARE overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-05 date: 2026-12 date: 2024-03-27 date: 2024-03-27 name: Hôpital Européen Marseille class: OTH... |
Onco-sexology is one of the supportive care services validated by The French National Cancer Institute (INCa). It is also an objective of the 2014-2019 cancer plan and the 2017-2030 national sexual health strategy plan. |
Although sexuality is one of the fundamental needs of the human being, including in the case of a chronic disease or cancer diagnosis, the lack of training of health professionals to deal with intimate life, the difficulty to exchange on this subject between caregivers and patients, the lack of financial support for on... |
While onco-sexology is already recommended as supportive care, a study on the impact of the delay in the management of sexual difficulties on quality of life could provide a sufficient level of evidence to change the practices and the care pathway of the oncology patient. Our objective is to study whether early managem... |
<|newrecord|> nctId: NCT06332560 id: NL86247.091.24 briefTitle: Pain in Endometriosis And the Relation to Lifestyle acronym: PEARL overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-05 date: 2027-05 date: 2024-03-27 date: 2024-03-27 name: Radboud University Medical Center class: OTHER name: ZonMw: The Netherlan... |
Participants will be randomized between standard care (control group), standard care and an anti-inflammatory diet, or standard care, anti-inflammatory diet and cognitive behavioral therapy. |
Participants will follow an anti-inflammatory diet based on the Dutch Dietary Guidelines for 12 weeks. They will receive personalized dietary advice from a dietician and recipes will be available. cognitive behavioral therapy will be administered in a total of seven individual sessions led by a psychotherapist. The con... |
<|newrecord|> nctId: NCT06332547 id: TICVS briefTitle: Transfusion in Cardiac Valve Surgery acronym: TICVS overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2027-12-30 date: 2027-12-30 date: 2024-03-27 date: 2024-03-27 name: Guangdong Provincial People's Hospital class: OTHER briefSummary: This prospective, rand... |
<|newrecord|> nctId: NCT06332534 id: M14-671 briefTitle: Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease overallStatus: NOT_YET_RECRUITING date: 2024-07-26 date: 2032-03-22 date: 2034-12-20 date: 2024-03-27 date: 2024-03-27... |
Upadacitinib (RINVOQ) is a drug approved in adults for moderate- to severely active CD and is being developed for moderate- to severely active CD in pediatric participants. This study is conducted in 2 periods: Period 1 is comprised of two phases: a 12-week open-label induction phase which means that the study doctor a... |
Participants will receive upadacitinib oral tablets once daily or oral solution twice daily at approximately the same time each day, with or without food. Participants will have a safety follow up for 30 days after discontinuation from any time point within the study. |
There may be higher treatment burden for participants in this trial compared to their standard of care (due to study procedures). Participants will attend regular (weekly, monthly) visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking ... |
<|newrecord|> nctId: NCT06332521 id: 23CH296 id: ANSM type: OTHER domain: 2024-A00286-41 briefTitle: Infant Crying, a Bioacoustic Prognostic Signal for Neurodevelopment acronym: BABYCRY_1000 overallStatus: RECRUITING date: 2024-03-20 date: 2029-04-01 date: 2029-04-01 date: 2024-03-27 date: 2024-04-26 name: Centre Hospi... |
Crying is usually caused by pain, discomfort, hunger, or separation from parents or other caregivers. Crying carries essential information from birth, the expression of which depends closely on the neuroanatomical and functional brain integrity of the child. On a bioacoustic level, crying consists of sequences of compl... |
<|newrecord|> nctId: NCT06332508 id: 2022/00406 briefTitle: Pulsed Electromagnetic Fields (PEMFs) - A Highly Selective Breast CAncer Treatment pLatform (PASCAL) overallStatus: RECRUITING date: 2022-12-30 date: 2025-12 date: 2025-12 date: 2024-03-27 date: 2024-03-27 name: National University Hospital, Singapore class: O... |
<|newrecord|> nctId: NCT06332495 id: RC23_0573 id: 2024-A00025-42 type: OTHER domain: ANSM (IDRCB) briefTitle: Research Project on the Risk of Discomfort, Pain, Alteration of Skin Condition in Bedpan Use by Patients and Caregivers acronym: RIDAECUBA overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-06-01 da... |
The objective is to evaluate pain in patients with reduced or very reduced mobility caused by the bedpan currently used in current practice through an observational study. conditions: Nurse-Patient Relations studyType: OBSERVATIONAL observationalModel: CASE_ONLY timePerspective: PROSPECTIVE count: 300 type: ESTIMATED n... |
<|newrecord|> nctId: NCT06332482 id: M0303023RP briefTitle: Complete Digital Workflow for Construction of Full Arch Implant Supported Screw Retained Restoration overallStatus: ACTIVE_NOT_RECRUITING date: 2023-03-30 date: 2024-05-20 date: 2024-09-15 date: 2024-03-27 date: 2024-03-27 name: Mansoura University class: OTHE... |
<|newrecord|> nctId: NCT06332469 id: INSERT feasibility briefTitle: Evaluation of an Internet Based Education and Support Program for Patients Awaiting Kidney Transplantation acronym: INSERT overallStatus: NOT_YET_RECRUITING date: 2024-04-08 date: 2025-10-31 date: 2025-10-31 date: 2024-03-27 date: 2024-03-27 name: Link... |
<|newrecord|> nctId: NCT06332456 id: ICM 2023-3169 briefTitle: Assessment of Renal Microcirculation With Rubidium Positron Emission Tomography acronym: RESIST overallStatus: RECRUITING date: 2023-07-04 date: 2024-12 date: 2024-12 date: 2024-03-27 date: 2024-03-27 name: Matthieu Pelletier-Galarneau, MD MSc class: OTHER ... |
<|newrecord|> nctId: NCT06332443 id: CER-CEMTL-2023-3086 briefTitle: Randomized, Controlled Trial Comparing the Effectiveness of Sedation-Epidural Anesthesia to Spinal Anesthesia in Outpatient Hip or Knee Arthroplasty. acronym: RCT SEA vs SA overallStatus: RECRUITING date: 2023-03-15 date: 2025-03-15 date: 2026-03-15 d... |
<|newrecord|> nctId: NCT06332430 id: CW-202 briefTitle: Intratumoral CAN2109 in Subjects With Solid Tumors or Lymphomas overallStatus: NOT_YET_RECRUITING date: 2024-05-30 date: 2025-05-30 date: 2026-05-30 date: 2024-03-27 date: 2024-03-27 name: Canwell Biotech Limited class: INDUSTRY briefSummary: A phase 1, dose escal... |
<|newrecord|> nctId: NCT06332417 id: REC/RCR&AHS/23/0364 briefTitle: Combined Effects of Ba-Duan-Jin Based Deep Breathing Exercises and Forced Expiratory Technique overallStatus: RECRUITING date: 2024-02-29 date: 2024-06-05 date: 2024-06-15 date: 2024-03-27 date: 2024-03-27 name: Riphah International University class: ... |
<|newrecord|> nctId: NCT06332404 id: B3002024000047 briefTitle: Hypoglossal Nerve Stimulation Therapy in Patients With Obstructive Sleep Apnea: Belgian Registry acronym: B-HNS overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2034-04 date: 2034-04 date: 2024-03-27 date: 2024-03-27 name: University Hospital, Antwerp... |
The aim is to create a registry of OSA patients that are treated with HNS (Inspire system) within routine clinical care at the Antwerp University Hospital. conditions: Obstructive Sleep Apnea conditions: Sleep Apnea conditions: Apnea studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count... |
<|newrecord|> nctId: NCT06332391 id: 202308349 id: R01HL168752 type: NIH link: https://reporter.nih.gov/quickSearch/R01HL168752 briefTitle: Paced Heart Rate Acceleration for Cardiac Conditioning acronym: HeartExcel overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2028-06-30 date: 2028-11-30 date: 2024-03-27 dat... |
<|newrecord|> nctId: NCT06332378 id: sHasan briefTitle: Effect of Exercise Therapy on Type II Diabetic Neuropathic Patients overallStatus: NOT_YET_RECRUITING date: 2024-04-02 date: 2024-08-15 date: 2024-08-15 date: 2024-03-27 date: 2024-03-27 name: Dr. Sobia Hasan class: OTHER briefSummary: The goal of this Randomized ... |
Exclusion criteria of the study will lower extremity complications such as fracture, having experience dislocation at least six months prior to the study, having any history of surgical operations in muscles, bones, and joints of lower extremities, suffering from musculoskeletal disorders such as rheumatoid arthritis a... |
The main question it aims to answer are: |
1. To compare the effects of two therapeutic exercises on clinical balance measures on type II diabetic peripheral neuropathy patients. |
2. Effectiveness of exercises using Swiss ball in lowering waist circumference, and BMI. |
3. Effectiveness of exercises on fasting blood sugar (FBS), post-prandial blood sugar (PPBS), and glycosylated Hemoglobin (HbA1c) among Type II diabetic patients. |
4. Effectiveness of exercises on autonomic nervous system activity on type II diabetic peripheral neuropathy patients. |
By using random allocation, the participants will divided into three groups: an intervention group (N=30) that receive ball training exercise, another intervention group (N=30) that receive Frenkel training exercise and a control group (N=30). |
Each exercise session contain 5 min warm-up (stationary bike), 45 min exercise training (with 1 minute rest for every 5 minutes of exercise), and 5 min of cool down activities including stretching of the muscles involved in balance exercise (gluteal, erector spine, hamstring, rectus femorus, gastro soleus, and pectoral... |
<|newrecord|> nctId: NCT06332365 id: ID: 3938/2022 briefTitle: Evaluating Treatment Efficacy in Oral Lichen Planus: The Role of Salivary Biomarkers acronym: salivaLichen overallStatus: COMPLETED date: 2022-01-03 date: 2023-12-15 date: 2024-02-19 date: 2024-03-27 date: 2024-03-27 name: Pia Lopez Jornet class: OTHER brie... |
Masking: Medications were prepared and packaged in identical, sealed, and numbered envelopes by the hospital pharmacy and a clinician not involved in the subsequent phases of the study. Each sealed envelope contained the protocol assignment for individual patients and written instructions for the application of the med... |
<|newrecord|> nctId: NCT06332352 id: 00173470 briefTitle: Intra-articular Platelet-Rich Plasma for Acetabular Labral Tears acronym: PRP for ALT overallStatus: RECRUITING date: 2024-01-25 date: 2025-01-25 date: 2026-01-25 date: 2024-03-27 date: 2024-03-27 name: University of Utah class: OTHER briefSummary: Platelets are... |
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