text stringlengths 0 197k |
|---|
The goal of this clinical trial is to learn more about the feasibility of offering rTMS as a treatment in the Nicotine Dependence Clinic (NDC) to help daily smokers to quit smoking. The NDC is at the Center for Addiction and Mental Health (CAMH) at 1025 Queen Street West, in Toronto, Canada. |
Participants will be asked to come to CAMH to: |
* Complete surveys and optional interviews to learn more about their opinions and experiences with this treatment |
* Start a treatment course that includes 3 weeks of daily (Monday to Friday) rTMS sessions followed by 3 weeks of weekly rTMS sessions for a total of 6 weeks. Each session lasts about 25 minutes and is provided by an rTMS technician with medical supervision. |
Objectives |
• Learning about the feasibility of rTMS as a treatment option for patients in the NDC will help us improve the treatment when offering it in other clinics, which may help improve smoking quit rates and people's overall health. conditions: Smoking studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionMode... |
<|newrecord|> nctId: NCT06346015 id: HX-A-2023050 briefTitle: Gamma Entrainment Stimulation for Cognitive Dysfunction After aSAH acronym: GES-aSAH overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-03-31 date: 2025-03-31 date: 2024-04-03 date: 2024-04-03 name: Beijing Tiantan Hospital class: OTHER name: Shan... |
<|newrecord|> nctId: NCT06346002 id: 2026_e_2017 briefTitle: Impact of a Mindfulness-based Intervention on Well-being and Mental Health of Elementary School Children overallStatus: COMPLETED date: 2017-03-01 date: 2020-03-31 date: 2020-03-31 date: 2024-04-03 date: 2024-04-03 name: Bishop's University class: OTHER brief... |
Aim: This study used a randomized cluster design and assessed the impact of a MBI on well-being and mental health of elementary school children's. |
Method: 13 elementary school classrooms were randomly allocated to the experimental condition (7 classrooms, n = 127 students) or the waitlist control condition (6 classrooms, n = 104 students). Participants in the experimental condition received a 10-week MBI. conditions: Mindfulness-based Intervention conditions: Ele... |
<|newrecord|> nctId: NCT06345989 id: 187157 briefTitle: Time and Cost-implications of Intraoral Scans vs Alginate Impressions: A Randomised Controlled Trial overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-06 date: 2025-12 date: 2024-04-03 date: 2024-04-03 name: University of Sheffield class: OTHER name: Nott... |
Whilst the majority of the available literature reveals patient preference in favour of intraoral scanning, it remains common practice to use alginate impressions for orthodontic records. Considerations such as time implications, device costs, associated software expenses, and the need for clinician training pose chall... |
The main question being addressed is: |
- Are intraoral scans more time efficient than alginate impressions? |
The secondary question being addressed is: |
- Are intraoral scans more cost effective than alginate impressions? |
This research protocol outlines a clinical trial, evaluating the chairside time and costs associated with intraoral scanning versus alginate impressions. The sample population will be orthodontic patients ages 9 years and above attending the orthodontic department at a district general hospital. |
The outcomes of this study will provide important insights into the practicality and economic viability of intraoral scanning versus alginate impressions in orthodontic settings, thereby informing clinical practices within the United Kingdom. This research contributes to strengthening the evidence base surrounding orth... |
<|newrecord|> nctId: NCT06345976 id: RLX_2023_10 briefTitle: Functional Impairment in Albinism acronym: PLAIB overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-04-03 date: 2024-04-03 name: Fondation Ophtalmologique Adolphe de Rothschild class: NETWORK briefSummary: Albinism is a gen... |
* In the integumentary region: fair skin tone, with white hair, eyelashes and eyebrows. |
* Ophthalmological: reduced visual acuity, photophobia, nystagmus, transilluminated blue irises, hypopigmentation of the retina at the back of the eye with fovea plana. |
As treatment options begin to emerge for certain albinism-induced anomalies (including, for example, the depigmentation that causes photophobia), it is desirable to understand what these patients' complaints are, and to gather their views on the emergence of treatments targeting just one of their complaints, namely gla... |
<|newrecord|> nctId: NCT06345963 id: HSC-MS-23-1044 briefTitle: Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1) overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2029-05-01 date: 2030-05-01 date: 2024-04-03 date: 2024-04-05 name: The University of Texas Health Science Center, Hous... |
<|newrecord|> nctId: NCT06345950 id: 2022-04-003 briefTitle: Pharmacokinetics and Safety of a New Micellar Glutathione Formulation overallStatus: COMPLETED date: 2022-06-21 date: 2022-12-31 date: 2023-06-30 date: 2024-04-03 date: 2024-04-03 name: Factors Group of Nutritional Companies Inc. class: INDUSTRY name: Isura b... |
The primary objective of this study is to evaluate and compare the pharmacokinetics of a novel micellar Glutathione (GSH) formulation with that of a standard formulation as well as a liposomal GSH formulation. The secondary objective is to evaluate the safety of a new micellar GSH formulation with higher bioavailabilit... |
<|newrecord|> nctId: NCT06345937 id: REB #44724 briefTitle: Multiple Risk Factor Intervention Trial (Ms. FIT) acronym: MsFIT overallStatus: RECRUITING date: 2024-04-01 date: 2027-08-01 date: 2028-08-01 date: 2024-04-03 date: 2024-04-04 name: University of Toronto class: OTHER name: Canadian Institutes of Health Researc... |
* How does the impact of exercise compare among each of the causal links between physical inactivity and cardiometabolic disease in women? |
* What is the effect modification of adding a diet quality intervention to exercise? |
* What is the effect modification by menopausal status? |
The investigators hypothesize that exercise adaptations will be: 1) largest peripherally, including Matsuda index (primary outcome), Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), arteriovenous oxygen difference (avO2diff), and visceral fat, compared to centrally (stroke volume (SV), endothelial function... |
<|newrecord|> nctId: NCT06345924 id: Meraki_Palliative Care briefTitle: Music Therapy for Cancer Patients(Meraki_PC) acronym: Meraki_Cancer overallStatus: RECRUITING date: 2024-03-01 date: 2024-07 date: 2025-07 date: 2024-04-03 date: 2024-04-15 name: University of Valencia class: OTHER briefSummary: The overall aim of ... |
Specifically, the implementation of an individualised treatment programme for palliative care patients will be carried out. conditions: Cancer conditions: Palliative Care studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: NONE count: 80 type: ... |
<|newrecord|> nctId: NCT06345911 id: NEU-49/899 briefTitle: Do Vacutainers With Animal Characters Reduce Fear and Anxiety? overallStatus: COMPLETED date: 2021-12-01 date: 2022-02-25 date: 2022-03-30 date: 2024-04-03 date: 2024-04-03 name: Burdur Mehmet Akif Ersoy University class: OTHER briefSummary: The study was desi... |
<|newrecord|> nctId: NCT06345898 id: 2023-1479 briefTitle: Safety and Efficacy of a Single Subretinal Injection of JWK002 Gene Therapy in Subjects With X-linked Retinoschisis(XLRS) overallStatus: RECRUITING date: 2023-11-17 date: 2026-12-30 date: 2029-12-30 date: 2024-04-03 date: 2024-04-03 name: West China Hospital cl... |
<|newrecord|> nctId: NCT06345885 id: PROPMHP002 briefTitle: Immunogenicity and Safety of One Dose of HPV Vaccine overallStatus: COMPLETED date: 2023-02-23 date: 2024-01-17 date: 2024-01-17 date: 2024-04-03 date: 2024-04-03 name: Xiamen Innovax Biotech Co., Ltd class: INDUSTRY briefSummary: This study will assess the im... |
<|newrecord|> nctId: NCT06345872 id: STUDY005883 id: 1R01DA054311 type: NIH link: https://reporter.nih.gov/quickSearch/1R01DA054311 briefTitle: Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain overallStatus: RECRUITING date: 2024-04 date: 2028-01 date: 2028-07 date: 2024-04-03 date: 2024-04-18 n... |
<|newrecord|> nctId: NCT06345859 id: UP-23-00467 id: R01MH133842 type: NIH link: https://reporter.nih.gov/quickSearch/R01MH133842 briefTitle: Regulation of Affect and Physiology in Depression acronym: RAPID overallStatus: RECRUITING date: 2024-03-22 date: 2028-04-30 date: 2029-06-30 date: 2024-04-03 date: 2024-04-03 na... |
<|newrecord|> nctId: NCT06345846 id: Secondary IOL briefTitle: Stability of Secondary Intraocular Lenses With no Capsular Support overallStatus: ENROLLING_BY_INVITATION date: 2022-12-30 date: 2025-12 date: 2025-12 date: 2024-04-03 date: 2024-04-03 name: Vienna Institute for Research in Ocular Surgery class: OTHER brief... |
<|newrecord|> nctId: NCT06345833 id: ENT-2024-32847 briefTitle: Topical and Local TXA in Facelifts - A Randomized Controlled Double Blinded Study overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2026-07-01 date: 2026-07-01 date: 2024-04-03 date: 2024-04-10 name: University of Minnesota class: OTHER briefSummary... |
Although TXA has been widely used in surgical fields for decades and is officially recommended by agencies such as ACOG for use during maternal hemorrhage, its current FDA approval only pertains to oral TXA for heavy menstrual bleeding and IV use for patients with hemophilia to prevent or reduce hemorrhage (cite). The ... |
<|newrecord|> nctId: NCT06345820 id: Evolux briefTitle: Comparison of Two Non-diffractive Enhanced Monofocal Intraocular Lenses overallStatus: RECRUITING date: 2023-06-28 date: 2025-06 date: 2025-06 date: 2024-04-03 date: 2024-04-04 name: Vienna Institute for Research in Ocular Surgery class: OTHER briefSummary: Compar... |
<|newrecord|> nctId: NCT06345807 id: 2023-A02617-38 briefTitle: Innovative Care Pathway in Physical Activity and Behavior Change in Coronary Patients Post-cardiac Rehabilitation acronym: APIC overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2026-11 date: 2026-11 date: 2024-04-03 date: 2024-04-05 name: Elsan class:... |
<|newrecord|> nctId: NCT06345794 id: 27111 id: J5C-MC-FOAG type: OTHER domain: DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company briefTitle: A Study to Assess LY4100511 (DC-853) in Healthy Adult Participants overallStatus: NOT_YET_RECRUITING date: 2024-04-03 date: 2024-06-17 date: 2024-06-17 date: 2... |
<|newrecord|> nctId: NCT06345781 id: 2174433-1 briefTitle: Abdominal Functional Electrical Stimulation to Improve Bowel Function in Spinal Cord Injury overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2025-05 date: 2024-04-03 date: 2024-04-03 name: Craig Hospital class: OTHER name: Neuroscience Resear... |
<|newrecord|> nctId: NCT06345768 id: 147258369 briefTitle: The Effect of the Stress Ball Applied Before Colocystectomy Surgery on Patients' Fear, Stress and Comfort. overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-08-01 date: 2024-09-01 date: 2024-04-03 date: 2024-04-03 name: Akdeniz University class: OTH... |
Stress ball, one of the distraction methods, is an effective method in providing cognitive focus. It is seen that the stress ball method is used to reduce patients' anxiety and pain. Squeezing the stress ball during the surgical procedure allows patients to have direct control over the object, increasing their sense of... |
In this study, it is aimed to evaluate the effect of preoperative use of stress ball on patients' fear, stress and comfort in order to determine the effect of stress ball applied before cholecystectomy surgery on patients' surgical fear, stress and comfort. It is thought that the data obtained as a result of the resear... |
<|newrecord|> nctId: NCT06345755 id: VX23-407-001 briefTitle: A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of VX-407 in Healthy Participants overallStatus: RECRUITING date: 2024-04 date: 2025-04 date: 2025-04 date: 2024-04-03 date: 2024-04-26 name: Vertex Pharmaceuticals Incorporated clas... |
<|newrecord|> nctId: NCT06345742 id: ATADEK-2023-10/396 briefTitle: The Effect of Parental Participation on Newborn Comfort During Diaper Care overallStatus: RECRUITING date: 2023-12-19 date: 2025-02-01 date: 2025-02-01 date: 2024-04-03 date: 2024-04-03 name: Acibadem University class: OTHER briefSummary: It was aimed ... |
H1: Parental participation during infant diaper care practice in preterm infants has an effect on newborn comfort. |
H2: There is a difference in the effect of parent diaper care practice and the participation of the mother or father on newborn comfort in preterm infants. |
H3: There is a difference between the stress levels of parents before the application of infant diaper care in preterm infants. conditions: Preterm studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: NONE count: 105 type: ESTIMATED name: No pa... |
<|newrecord|> nctId: NCT06345729 id: 1084-004 id: MK-1084-004 type: OTHER domain: Merck id: U1111-1296-8093 type: OTHER domain: UTN id: 2023-507776-42 type: REGISTRY domain: EU CT briefTitle: A Study of MK-1084 Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant, Metastatic Non-small Cell Lung Cancer (NS... |
Hypothesis 1: Combination of MK-1084 and pembrolizumab is superior to placebo plus pembrolizumab with respect to progression free survival (PFS) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1) by blinded independent central review (BICR). |
Hypothesis 2: Combination of MK-1084 plus pembrolizumab is superior to placebo plus pembrolizumab with respect to overall survival (OS). conditions: Non-small Cell Lung Cancer studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: TRIPLE whoMasked:... |
<|newrecord|> nctId: NCT06345716 id: renal colic 2024 briefTitle: Paracetamol-Tramadol and Paracetamol-caffeine Versus Placebo in the Emergency Discharge Treatment of Renal Colic acronym: RC overallStatus: NOT_YET_RECRUITING date: 2024-04-10 date: 2025-03-15 date: 2025-11-30 date: 2024-04-03 date: 2024-04-03 name: Univ... |
<|newrecord|> nctId: NCT06345703 id: NeuShen Therapeutics briefTitle: First-into-human Study of NS-136 in Healthy Subjects overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-11 date: 2025-02 date: 2024-04-03 date: 2024-04-03 name: NeuShen Therapeutics class: INDUSTRY briefSummary: The goal of this clinical tria... |
* Is NS-136 safe and tolerable in heathy subjects under tested dosing regimen? |
* What is the pharmacokinectic profile of NS-136 in healthy subjects under tested dosing regimen? conditions: Healthy Subjects studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: SEQUENTIAL interventionModelDescription: The trial consists of three parts: the first part is a single ascendi... |
<|newrecord|> nctId: NCT06345690 id: VIA-2023-003 briefTitle: VIA Disc NP Registry 3.0 overallStatus: RECRUITING date: 2024-02-27 date: 2027-01-01 date: 2027-01-01 date: 2024-04-03 date: 2024-04-03 name: VIVEX Biologics, Inc. class: INDUSTRY name: Moxie Clinical briefSummary: Registry is to observe and trend patterns o... |
<|newrecord|> nctId: NCT06345677 id: ViXe-CLP-0002 briefTitle: Clinical Trial for the Assessment of Safety, Usability and Efficacy of the Vixe Combination for OAB in Female Subjects acronym: XAVIER overallStatus: COMPLETED date: 2023-06-09 date: 2024-02-01 date: 2024-02-01 date: 2024-04-03 date: 2024-04-09 name: Vensic... |
<|newrecord|> nctId: NCT06345664 id: 548/2022BO1 briefTitle: Interdisciplinary E-health Based Follow-up of Preterm Born Children acronym: NeoUp overallStatus: RECRUITING date: 2023-03-01 date: 2024-10 date: 2024-12 date: 2024-04-03 date: 2024-04-08 name: University Hospital Tuebingen class: OTHER briefSummary: The aim ... |
<|newrecord|> nctId: NCT06345651 id: 2023-03, Version 7 briefTitle: Brain Oscillation-synchronized Stimulation of the Frontal Cortex in Major Depressive Disorder acronym: BOSSFRONT2 overallStatus: RECRUITING date: 2023-09-01 date: 2025-08 date: 2025-08 date: 2024-04-03 date: 2024-04-03 name: University Hospital Tuebing... |
<|newrecord|> nctId: NCT06345638 id: 854343 briefTitle: Sex Hormones and Inflammatory Biomarkers in Patients With Sickle Cell Disease overallStatus: ENROLLING_BY_INVITATION date: 2024-03-01 date: 2025-04-30 date: 2025-05-31 date: 2024-04-03 date: 2024-04-03 name: University of Pennsylvania class: OTHER briefSummary: Th... |
* The study will compare CRP and other biomarkers between females with SCD in the follicular phase of the menstrual cycle and males with SCD. |
* The study will explore potential sex differences in biomarker changes between females and males with SCD during and following resolution of VOC. |
* The study will compare neutrophil and platelet adhesion to the endothelium and real time fibrin deposition in the blood. conditions: Sickle Cell Disease conditions: Vaso-occlusive Crisis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 40 type: ESTIMATED measure: C-reactive prot... |
<|newrecord|> nctId: NCT06345625 id: 6012 briefTitle: Gait and Postural Balance Analysis During Head-motion Perturbed Standing and Walking in Older Adults acronym: BALANCAR overallStatus: RECRUITING date: 2024-04-15 date: 2027-01 date: 2028-01 date: 2024-04-03 date: 2024-04-16 name: Universiteit Antwerpen class: OTHER ... |
<|newrecord|> nctId: NCT06345612 id: Hypoxia-Exercise-DiabetesT1 briefTitle: Impact of Eccentric Training in Hypoxia With Creatine on Metabolic Control and VO2max in Patients With Type 1 Diabetes overallStatus: RECRUITING date: 2023-11-15 date: 2025-06 date: 2025-07 date: 2024-04-03 date: 2024-04-03 name: Silesian Cent... |
<|newrecord|> nctId: NCT06345599 id: LK2023100 briefTitle: PRaG Therapy in Combination With Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC) (NeoPRAG Study) overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-01-10 date: 2027-01-10 date: 2024-04-03 date: 2024-04-03 name: Second Affiliated Hospital of ... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.