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<|newrecord|> nctId: NCT06346405 id: 10 briefTitle: Central Serous Chorioretinopathy and Micropulse Laser Treatment acronym: LEVEO overallStatus: RECRUITING date: 2023-05-31 date: 2025-05-31 date: 2025-05-31 date: 2024-04-04 date: 2024-04-04 name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS class: OTHER... |
<|newrecord|> nctId: NCT06346392 id: D9802C00001 briefTitle: AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2 overallStatus: RECRUITING date: 2024-03-04 date: 2026-04-10 dat... |
Arm 1: AZD0901 arm 1 IV, Q3W Arm 2: AZD0901 arm 2 IV, Q3W Arm 3: Participants in the Investigator's choice arm, including regionally accepted chemotherapies or targeted therapies 2L: Ramucirumab 8 mg/kg IV on Days 1 and 15 and paclitaxel 80 mg/m2 IV on Days 1, 8, and 15, Q4W 2L: Paclitaxel 80 mg/m2 IV on Days 1, 8, and... |
<|newrecord|> nctId: NCT06346379 id: 2023-K086-01 briefTitle: The Effect of Baduanjin on Physical Fitness and Bone Density in Maintenance Hemodialysis Patients overallStatus: RECRUITING date: 2024-04-01 date: 2024-05-01 date: 2025-10-01 date: 2024-04-04 date: 2024-04-19 name: Affiliated Hospital of Nantong University c... |
<|newrecord|> nctId: NCT06346366 id: NL.82557.018.22 briefTitle: Glucose Control Through a Bihormonal Artificial Pancreas in Patients After Total Pancreatectomy acronym: PANORAMA overallStatus: ACTIVE_NOT_RECRUITING date: 2023-04-25 date: 2024-04-01 date: 2024-04-01 date: 2024-04-04 date: 2024-04-04 name: Academisch Me... |
The CE marked bihormonal artificial pancreas (BIHAP) provides continuous fully automatic glucose monitoring and administration of insulin and glucagon using a self-learning algorithm. In a recent pilot study (APPEL5+, NL.8871) the BIHAP was being compared to current diabetes treatment in 10 patients after total pancrea... |
Now, larger randomized studies with a longer treatment period are necessary to confirm safety and efficacy of BIHAP for the treatment of diabetes in patients after total pancreatectomy, with sufficient attention for long-term glycemic control (HbA1c) and patient-reported outcomes. |
The PANORAMA trial will evaluate the efficacy of a 3-month treatment with BIHAP in 40 patients after total pancreatectomy as compared to a 3-month treatment period with current diabetes care in a randomized cross-over trial. Patients will be randomized to start with the BIHAP (after a training period) or current diabet... |
<|newrecord|> nctId: NCT06346353 id: Chess Cognition SUD briefTitle: Substance Consumption, Personality, and Cognitive Functioning of Chess Players overallStatus: RECRUITING date: 2024-01-31 date: 2024-05-31 date: 2024-05-31 date: 2024-04-04 date: 2024-04-04 name: Central Institute of Mental Health, Mannheim class: OTH... |
<|newrecord|> nctId: NCT06346340 id: 936 briefTitle: A Study to Evaluate the Effect of Miebo™ on Preoperative Biometry/Keratometry and Postoperative Refractive Accuracy overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-11 date: 2024-09 date: 2024-09 date: 2024-04-04 date: 2024-04-04 name: Bausch & Lomb Incorporated cl... |
<|newrecord|> nctId: NCT06346327 id: Absent End-Diastolic Flow briefTitle: Clinical Significance Of Intermittently Absent End-Diastolic Flow Of The Fetal Umbilical Artery On Perinatal And Neonatal Outcomes Dr. Zeynep Kayaoğlu Yıldırım Dr. Alperen İnce Dr Gökhan Bayanmelek Dr Gökhan Bolluk overallStatus: COMPLETED date:... |
Study design: We performed a retrospective cohort study of patients diagnosed with the iAEDF or pAEDF at our institution from 2020 to 2023. Fetuses were classified under two categories: iAEDF group and pAEDF group.Neonatal outcomes, demographic information, pregnancy outcomes and pregnancy complications were compared b... |
<|newrecord|> nctId: NCT06346314 id: 12241976 briefTitle: Is There an Immediate Effect on Pectoralis Minor Length After Performing a Prone Scapular Retraction Exercise overallStatus: COMPLETED date: 2021-07-15 date: 2022-01-10 date: 2022-01-10 date: 2024-04-04 date: 2024-04-04 name: Andrews University class: OTHER brie... |
The main question it aims to answer is: |
• Do the participant's pectoralis minor muscles change length immediately after performing an exercise that recruits the scapular retractor muscles? Participants will have their pectoralis minor muscle measured, then perform an exercise recruiting the scapular retractor muscles, and then have their pectoralis muscle me... |
<|newrecord|> nctId: NCT06346301 id: NL83374.018.23 briefTitle: Imagery Rescripting as a Stand-alone Treatment for OCD and BDD. overallStatus: RECRUITING date: 2023-04-21 date: 2026-01 date: 2027-01 date: 2024-04-04 date: 2024-04-04 name: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) class: OTHER br... |
Primary objective :The course of schema or core beliefs and change in OCD and BDD. To investigate the effectiveness of imagery rescripting on factors presumed to underlie the disorder, according to schema theory, and on OCD and BDD symptoms. |
Secondary objective: The change in OCD and BDD symptoms (full questionnaire), schemata and modes, core emotions, mood, affect and obtrusiveness of intrusion. |
Other objectives are research into the working mechanisms of imagery rescripting by collecting qualitative data from patients and their practitioner in a qualitative interview. |
For this study, a multiple-baseline single-case experimental design (SCED) is used testing different outcome variables in 18 OCD patients and 18 BDD patients. After a variable baseline period of 3-8 weeks participants will start twice weekly with imagery rescripting for 12 sessions, followed by a 6 week follow up. |
Participants will rate schema- or core beliefs and OCD or BDD severity on a visual analogue scale. In addition participants will rate core emotions, affect and obtrusiveness of the intrusion. Secondary we will asses four times questionnaires about OCD of BDD symptoms, depression and schemas en modes. After treatment pa... |
<|newrecord|> nctId: NCT06346288 id: M24-144 briefTitle: A Study to Assess the Concentrations of Risankizumab in the Breast Milk of Adult Lactating Women With Inflammatory Bowel Disease overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2025-01-20 date: 2025-05-27 date: 2024-04-04 date: 2024-04-24 name: AbbVie cl... |
Risankizumab is an approved drug for adults with plaque psoriasis, psoriatic arthritis, and Crohn's Disease. This is an open-label milk-only study lactation study to evaluate the presence of risankizumab in the milk of lactating women. Approximately 10 adult lactating women with IBD will be enrolled from approximately ... |
Participants will receive risakizumab maintenance therapy every 8 weeks postpartum prior to start of participation in this study. The study duration is approximately 7 months. |
Participants will attend regular visits during the study at a hospital or clinic. The participants will also be completing questionnaires and will have medical assessments, checking for side effects. conditions: Inflammatory Bowel Disease studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE... |
<|newrecord|> nctId: NCT06346275 id: 3rdZhejiangCMU-11 briefTitle: Effect of Acupuncture on the Gait Disturbance and Hemodynamic Changes in the Prefrontal Cortex overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2025-04 date: 2025-04 date: 2024-04-04 date: 2024-04-04 name: The Third Affiliated hospital of Zhejia... |
Methods: In this RCT, a total of 108 AD patients will be randomly assigned into acupuncture group or control group for 8 weeks. The primary outcome will be Three-dimensional gait analysis and cerebral hemodynamics using functional near-infrared spectroscopy (fNIRS). Secondary outcomes include Mini-Mental State Examinat... |
Discussion: This trial is expected to explore the effect of acupuncture on cognitive function, gait performance, and hemodynamic changes in the prefrontal cortices for AD patients. conditions: Alzheimer Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREAT... |
<|newrecord|> nctId: NCT06346262 id: STUDY20230921 briefTitle: Seizure Rescue Medication (RM) as Part of a Comprehensive Epilepsy Self-management Package of Care overallStatus: RECRUITING date: 2024-03-05 date: 2026-01-01 date: 2026-01-01 date: 2024-04-04 date: 2024-04-04 name: Martha Sajatovic class: OTHER briefSummar... |
Phase 2: The investigators will use a 6-month prospective trial design to test engagement with and effects of SMART-RM among approximately 35 adult (≥ 18 years) PWE who have repetitive seizures. conditions: Epilepsy studyType: INTERVENTIONAL phases: PHASE4 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: ... |
<|newrecord|> nctId: NCT06346249 id: 49/2024 briefTitle: Workplace Based Physiotherapy of Elderly-care Workers With Non-specific Neck Pain. overallStatus: RECRUITING date: 2024-03-04 date: 2024-05 date: 2024-05 date: 2024-04-04 date: 2024-04-04 name: Universidad de Extremadura class: OTHER briefSummary: The overall obj... |
<|newrecord|> nctId: NCT06346236 id: 69HCL21_0843 id: 401 type: OTHER domain: AGORA HCL briefTitle: Neurodevelopmental Impact of Treatment in Hypothyroxinaemia of Prematurity. acronym: NEO-TYR overallStatus: COMPLETED date: 2020-03-01 date: 2021-07-01 date: 2022-09-01 date: 2024-04-03 date: 2024-04-03 name: Hospices Ci... |
In this study, we aim to show that a treatment with L-thyroxine at a dose of 7.5 µg/kg/j for neonates diagnosed with THOP (defined as a level of l-T4 \< 12 pmol/L and a level of TSH \< 15 mUI/L before 15 days of life or \< 85 mUI/L after 15 days of birth) is associated with an increased neurodevelopmental prognosis. co... |
<|newrecord|> nctId: NCT06346223 id: HSEARS20230928006 briefTitle: Mindfulness-Based Intervention for Family Caregivers overallStatus: NOT_YET_RECRUITING date: 2024-08 date: 2025-08 date: 2025-08 date: 2024-04-03 date: 2024-04-04 name: The Hong Kong Polytechnic University class: OTHER name: Health and Medical Research ... |
Participants will be randomly assigned to receive either the mindfulness intervention combined with psychoeducation or psychoeducation alone. Evaluations will be conducted at baseline (0 weeks), immediately post-intervention (8 weeks), and during a follow-up assessment (6 months). Both groups will complete the same ass... |
<|newrecord|> nctId: NCT06346210 id: UNT: U1111-1288-2037 briefTitle: Optimal Timing for Tracheostomy in Invasively Mechanically Ventilated COVID-19 Patients overallStatus: COMPLETED date: 2024-04-02 date: 2024-04-02 date: 2024-04-02 date: 2024-04-03 date: 2024-04-10 name: Uppsala University class: OTHER name: Healthca... |
<|newrecord|> nctId: NCT06346197 id: ET23-185 briefTitle: Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas acronym: CIME overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2028-05-15 date: 2028-05-15 date: 2024-04-03 date: 2024-04-03 name: Centre Leon Berard c... |
<|newrecord|> nctId: NCT06346184 id: HM-EMMA-101 briefTitle: A Study to Evaluate the Pharmacokinetics and Safety Between HCP2303 and Co-administration of Each Component in Healthy Volunteers overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2024-06-08 date: 2024-06-08 date: 2024-04-03 date: 2024-04-12 name: Hanm... |
<|newrecord|> nctId: NCT06346171 id: 408/06.03.2024 briefTitle: VR Augmented Human Delivered Integrative Psychotherapy for Colonoscopy Procedural Anxiety and Pain acronym: VRIPanx-COL overallStatus: NOT_YET_RECRUITING date: 2024-04-28 date: 2024-08-30 date: 2024-11-30 date: 2024-04-03 date: 2024-04-05 name: Grigore T. ... |
Colonoscopy procedural anxiety not only exacerbates the experience of pain, but also may compromise the quality of bowel preparation, augment procedure and recovery room times, and increase the use of sedation, particularly among females, who report greater pre-procedural anxiety, and perceive the procedure to be more ... |
The profound positive corelation between anxiety and pain impact on outcomes of colonoscopy warrants an investigation of comprehensive patient care strategies. A growing body of evidence indicates that non-pharmacologic interventions, such as music therapy and immersive virtual reality (iVR), may effectively reduce anx... |
Understanding barriers to colonoscopy compliance, such as fear of cancer diagnosis, the perception of invasiveness, and feelings of embarrassment is paramount to enhancing CRC screening uptake, therefore lowering mortality. conditions: Procedural Anxiety conditions: Procedural Pain studyType: INTERVENTIONAL phases: NA ... |
<|newrecord|> nctId: NCT06346158 id: 2024-3615 briefTitle: Prediction of Propofol Effect-Site Concentration Associated With Deep Anesthesia acronym: PRESCOD-AI overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-04-03 date: 2024-04-03 name: Ciusss de L'Est de l'Île de Montréal class: ... |
The investigators hypothesized that there is a great variability in this Ce that could be precisely explained by |
* Electroencephalographic (EEG) features available prior to induction of anesthesia |
* Cognitive performance |
* Patients characteristics Participants will undergo preoperative cognitive testing and awake EEG. Then, induction of general anesthesia will be performed using continuous infusion of propofol. The Ce at which Deep anesthesia is observed will be recorded. conditions: Anesthesia studyType: OBSERVATIONAL observationalMod... |
<|newrecord|> nctId: NCT06346145 id: MIMS study id: 2023-00453 type: OTHER_GRANT domain: Swdeish research council briefTitle: Impact of Bariatric Surgery on Heart Disease Compared to Standard Care acronym: MIMS overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2028-05-01 date: 2030-05-01 date: 2024-04-03 date: 2... |
<|newrecord|> nctId: NCT06346132 id: 2024-00043 CE 4516 briefTitle: Effect of Virtual Reality on Patient's Comfort During Cardiac Electronic Device Implantation. overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-12-31 date: 2025-12-31 date: 2024-04-03 date: 2024-04-03 name: Schlotterbeck Hervé class: OTHER ... |
<|newrecord|> nctId: NCT06346119 id: PI-2023-01 briefTitle: Evaluation of the Impact of Touch Relaxation in Sedated Intubated Patients Hospitalized in Intensive Care at Niort Hospital acronym: ETDR overallStatus: RECRUITING date: 2023-02-27 date: 2024-01-05 date: 2025-12-31 date: 2024-04-03 date: 2024-04-03 name: Centr... |
<|newrecord|> nctId: NCT06346106 id: 23-0075 briefTitle: The Diagnostic Experience of Male Rett Syndrome overallStatus: RECRUITING date: 2023-05-24 date: 2024-04-30 date: 2024-04-30 date: 2024-04-03 date: 2024-04-03 name: Children's Hospital Colorado class: OTHER name: University of Colorado, Denver name: Vanderbilt Un... |
Enrolled participants will complete an online survey with questions about having a son with Rett Syndrome. The Diagnostic Experience of Male Rett Syndrome study is available to parents or caregivers to boys (alive or passed) with Rett Syndrome. Compensation is not provided. conditions: Rett Syndrome conditions: RTT stu... |
<|newrecord|> nctId: NCT06346093 id: CHEC2024-089 briefTitle: Fecal Microbiota Transplantation (FMT) in Patients With Advanced Gastric Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2026-12-31 date: 2026-12-31 date: 2024-04-03 date: 2024-04-03 name: Xiangyu Kong class: OTHER briefSummary: This study is... |
<|newrecord|> nctId: NCT06346080 id: s68670 briefTitle: Molecular Analysis for Gastro-Esophageal Cancer: Multicenter Discrete Choice Experiment acronym: MAGECmultiDiCE overallStatus: NOT_YET_RECRUITING date: 2024-08-01 date: 2026-08-01 date: 2026-08-01 date: 2024-04-03 date: 2024-04-03 name: KU Leuven class: OTHER brie... |
The main question it aims to answer are: |
* Which diagnostic modality is preferred by patients and the general population? |
* Which features of the diagnostic test are most detrimental in the decision-making for one or the other modality? |
* Are geographical differences present in regard to the preference for a diagnostic modality? |
Participants will be asked to complete a survey of 20-25min, including a brief intake regarding their socio-economic status. This approach will allow us to correct for confounding factors. conditions: Esophageal Cancer conditions: Gastric Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SIN... |
<|newrecord|> nctId: NCT06346067 id: ERAS-254-02 briefTitle: A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2) overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2028-04 date: 2028-12 date: 2024-04-03 date: 2024-04-29 name: Erasca, Inc. class: IN... |
Stage 2: To compare progression free survival (PFS) and overall survival (OS) for patients with NRAS-mutant (NRASm) melanoma who are randomized to receive the combination of naporafenib + trametinib to that of patients who are randomized to physician's choice of therapy (dacarbazine, temozolomide, or trametinib monothe... |
<|newrecord|> nctId: NCT06346054 id: s68669 briefTitle: Molecular Assessment for Gastro-Esophageal Cancer acronym: MAGEC overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2029-07-01 date: 2029-07-01 date: 2024-04-03 date: 2024-04-03 name: KU Leuven class: OTHER briefSummary: The goal of this minimally invasive i... |
The main questions this study aims to answer: |
Are oncometabolites proficient and reproducible enough to function as diagnostic biomarkers? Can these biomarkers identify early-stage gastro-esophageal cancer? Researchers will compare participants with gastro-oesophageal cancer to healthy controls and participants with Barrett's esophagus to detect meaningful differe... |
Participants will provide a breath and blood sample during their routine standard of care visits. conditions: Esophageal Cancer conditions: Gastric Cancer conditions: Barrett Esophagus studyType: INTERVENTIONAL phases: NA allocation: NON_RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Participants ... |
<|newrecord|> nctId: NCT06346041 id: HJG-IDOV-SAFE-LYSW briefTitle: Safety and Efficacy of Intravenous IDOV-SAFETM in Patients With Advanced Solid Tumors overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-31 date: 2026-04-01 date: 2024-04-03 date: 2024-04-03 name: Cancer Institute and Hospital, Chinese Ac... |
<|newrecord|> nctId: NCT06346028 id: 2023/086 briefTitle: Implementation of Transcranial Magnetic Stimulation for Smoking Cessation overallStatus: RECRUITING date: 2024-03-30 date: 2025-06-30 date: 2025-06-30 date: 2024-04-03 date: 2024-04-03 name: Centre for Addiction and Mental Health class: OTHER briefSummary: Repet... |
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