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Double-Bundle ACL + ALL Reconstruction Group: |
* Patients in this group will undergo anatomic double-bundle ACL reconstruction using two graft bundles to more anatomically replicate the native ACL's anteromedial and posterolateral bundles. |
* Like the single-bundle group, they will also have supplemental ALL reconstruction performed using a portion of the graft material. |
* The double-bundle ACL reconstruction aims to better restore the ACL's complex anatomic footprint and bundles' tension patterns. primaryPurpose: TREATMENT masking: NONE count: 40 type: ESTIMATED name: Single-bundle ACL combined anterolateral ligament reconstruction name: Double-bundle ACL combined anterolateral ligame... |
<|newrecord|> nctId: NCT06341179 id: M2S id: H-23063352 type: OTHER domain: Vek.dk briefTitle: Effect of Sleep Extension on Overweight and Learning in Children acronym: More2Sleep overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-12-31 date: 2027-12-31 date: 2024-04-02 date: 2024-04-02 name: University of C... |
The primary objective is to assess the effects of sleep extension by \~45 min/night, achieved by going to bed 60-90 min earlier, on adiposity and learning ability in school-aged children who are overweight or obese, and sleep less than recommended for their age. conditions: Sleep Duration conditions: Child Obesity cond... |
<|newrecord|> nctId: NCT06341166 id: CCM1959 briefTitle: Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse acronym: SCIMITAR overallStatus: RECRUITING date: 2023-06-19 date: 2025-06-19 date: 2025-06-19 date: 2024-04-02 date: 2024-04-02 name: Centro Cardiologico Monzino ... |
<|newrecord|> nctId: NCT06341153 id: SelcukUni2542 briefTitle: The Effect Of Breast Milk Sniffing And Tasting On Early Feeding Tips overallStatus: COMPLETED date: 2022-07-15 date: 2022-09-15 date: 2023-11-15 date: 2024-04-02 date: 2024-04-02 name: Sibel Küçükoğlu class: OTHER name: Health Institutes of Turkey briefSumm... |
Inclusion Criteria; For the mother; |
* Having a term and healthy baby, |
* No communication and language problems, |
* No maternal illness preventing breastfeeding (active chemotherapy, HIV positive, neurological or psychological problems, etc.), |
* Willingness to breastfeed, For the baby; |
* Not having a disease condition that prevents breastfeeding (cleft palate, cleft lip, galactotemia, choanal atresia, etc.), |
* Being at normal birth weight (2500gr-4000gr), |
* Apgar score of 7 and above. whoMasked: INVESTIGATOR count: 72 type: ACTUAL name: Breast Milk Odor Stimulation name: Stimulation of Breast Milk Smell and Taste measure: Introductory Information Form measure: Early Feeding Tips Scale measure: Breastfeeding Identification and Assessment Scale (LATCH) measure: Early Feed... |
<|newrecord|> nctId: NCT06341140 id: secil koken briefTitle: The Effect of Breastfeeding Support on Exclusive Breastfeeding, Occurrence of Breast Problems and Breastfeeding Self-Efficacy overallStatus: COMPLETED date: 2021-08-01 date: 2022-11-30 date: 2023-02-06 date: 2024-04-02 date: 2024-04-02 name: Celal Bayar Unive... |
<|newrecord|> nctId: NCT06341127 id: 2023-01 briefTitle: Fluoxetine in KCNC1-related Disorder overallStatus: ENROLLING_BY_INVITATION date: 2024-01-17 date: 2024-12-01 date: 2025-12-31 date: 2024-04-02 date: 2024-04-02 name: Holland Bloorview Kids Rehabilitation Hospital class: OTHER name: The Hospital for Sick Children... |
<|newrecord|> nctId: NCT06341114 id: BAT-8008-1308-001-CR briefTitle: A Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of the Combination of BAT8008 With BAT1308 in Patients With Advanced Solid Tumors overallStatus: NOT_YET_RECRUITING date: 2024-04-12 date:... |
This study aims to explore the safety, tolerability, and pharmacokinetic characteristics of BAT8008 combined with BAT1308 in patients with advanced solid tumors, determine the maximum tolerated dose (MTD), provide recommended doses and reasonable dosing regimens for subsequent clinical studies, and preliminarily evalua... |
The study is divided into two stages. The first stage will use a "3+3" dose escalation design to explore the safety and tolerability of the investigational drugs. In the second stage, based on the preliminary safety and efficacy results from the first stage, appropriate doses and tumor types will be selected for expans... |
<|newrecord|> nctId: NCT06341101 id: 2022-503135-33-00 id: 2022-503135-33-00 type: OTHER domain: EU trial number briefTitle: Timely Recovery After Subclinical Heart Failure acronym: TREASURE overallStatus: RECRUITING date: 2024-03-26 date: 2026-03-01 date: 2026-03-01 date: 2024-04-02 date: 2024-04-02 name: Academisch Z... |
1. Reversibility of structural and functional myocardial impairment in asymptomatic HF towards healthy values; |
2. The progression from asymptomatic to symptomatic HF (symptoms scored based on the NYHA criteria); |
3. Cardiovascular performance (volume- and pressure load), cardio metabolic risk factors (glucose metabolism, lipid status, kidney function) and quality of life (questionnaires); |
4. Novel biomarkers and relevant microRNA's indicative for hypertrophy, fibrosis inflammation and ischemia. |
Eligible subjects will be counselled and upon informed consent randomized for either medication group (n=65) or care as usual group (n=65). After a complete cardiovascular assessment, medication will be initiated open-labeled (Perindopril 2 mg or no medication). Thereafter, standard medical check-ups (blood pressure, E... |
Researchers will compare ACE inhibitor (Perindopril 2 mg) and care as usual (i.e. no medication) to investigate whether ACE inhibitor allows timely recovery after subclinical heart failure. conditions: Heart Failure conditions: Diastolic Dysfunction studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interv... |
<|newrecord|> nctId: NCT06341088 id: B.30.2.ATA.0.01.00/132 briefTitle: Evaluation of Anatomical Results and Sexual Functions After Unilateral and Bilateral Laparoscopic Suture Sacro-hysteropexy Operations overallStatus: RECRUITING date: 2024-04-05 date: 2024-07-05 date: 2024-10-05 date: 2024-04-02 date: 2024-04-02 nam... |
<|newrecord|> nctId: NCT06341075 id: KY2024-053-02 briefTitle: Real-World Study of Magnetic Resonance-guided Laser Interstitial Thermal Therapy for Drug-resistant Epilepsy overallStatus: ENROLLING_BY_INVITATION date: 2024-03-14 date: 2025-03-14 date: 2026-03-14 date: 2024-04-02 date: 2024-04-02 name: Beijing Tiantan Ho... |
<|newrecord|> nctId: NCT06341062 id: M2024078 briefTitle: The Application of Contrast-enhanced Ultrasound in Acute Kidney Injury in ICU overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-06-30 date: 2026-06-30 date: 2024-04-02 date: 2024-04-02 name: Peking University Third Hospital class: OTHER briefSummary:... |
1. To explore the quantitative parameters of contrast-enhanced ultrasound which can reflect the changes of renal microcirculation. |
2. To explore the relationship between renal microcirculation and systemic hemodynamics. |
3. To explore the value of renal microflow changes quantitatively evaluated by contrast-enhanced ultrasound in predicting renal function recovery. conditions: Intensive Care Unit conditions: Acute Kidney Injury conditions: Ultrasound studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count... |
<|newrecord|> nctId: NCT06341049 id: 2024-03/14 briefTitle: Effect of Three Different Postcesarean Analgesic Techniques on QbsQor-10 Score: Prospective, Randomized Trial overallStatus: RECRUITING date: 2024-03-12 date: 2024-06-12 date: 2025-09-12 date: 2024-04-02 date: 2024-04-02 name: Ataturk University class: OTHER b... |
<|newrecord|> nctId: NCT06341036 id: Thrombocytosis in Children briefTitle: Aetiology And Outcome Of Children With Thrombocytosis Admitted to Assiut University Children Hospital overallStatus: NOT_YET_RECRUITING date: 2024-07-15 date: 2025-03-03 date: 2026-03-03 date: 2024-04-02 date: 2024-04-02 name: Assiut University... |
<|newrecord|> nctId: NCT06341023 id: 2023-1430 briefTitle: Functional Balance Intervention in Multiple Sclerosis acronym: FBIinMS overallStatus: NOT_YET_RECRUITING date: 2024-04-14 date: 2026-01-09 date: 2027-01-09 date: 2024-04-02 date: 2024-04-03 name: University of Illinois at Chicago class: OTHER briefSummary: This... |
Study 1: Effect of lab-based Functional Balance Intervention (FBI) for physical and cognitive symptoms of Multiple Sclerosis. |
Study 2: Feasibility of home-based FBI for physical and cognitive symptoms of Multiple Sclerosis. |
Each study involves a 2-arm, Phase-1, randomized controlled clinical trial to evaluate the effect of FBI on physical, cognitive function, and daily living among people with MS (PwMS). Study 1 is conducted in a lab setting, while Study 2 is conducted at home with additional safety measures. A total of 150 people with mu... |
<|newrecord|> nctId: NCT06341010 id: The Role of Angiojet Rheolytic briefTitle: The Role of Angiojet Rheolytic Thrombectomy in The Management of Iliofemoral Deep Venous Thrombosis overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-01-01 date: 2026-09-01 date: 2024-04-02 date: 2024-04-02 name: Abdelrahman Ibr... |
<|newrecord|> nctId: NCT06340997 id: Mitral Stenosis briefTitle: Impact of Percutaneous Transvenous Mitral Commissurotomy on The Left Atrial Appendage Function in Patients With Mitral Stenosis. overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2026-10-01 date: 2027-08-01 date: 2024-04-02 date: 2024-04-02 name: A... |
<|newrecord|> nctId: NCT06340984 id: sICAM-1 in acne vulgaris briefTitle: Serum Intercellular Adhesion Molecule -1 in Acne Vulgaris Patients : Effect of Montelukast overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2024-11 date: 2025-02 date: 2024-04-02 date: 2024-04-03 name: South Valley University class: OTHER br... |
1. Evaluation of serum soluble intercellular adhesion molecule-1 (sICAM-1) level in acne vulgaris and compare it to control group |
2. Evaluate its role in acne pathogenesis and its correlation with acne vulgaris severity |
3. Evaluate the effect of Montelukast on serum (sICAM-1) level in acne vulgaris conditions: Acne Vulgaris studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: PARTICIPANT whoMasked: INVESTIGATOR count: 60 type: ESTIMATED name: M... |
<|newrecord|> nctId: NCT06340971 id: 331247 briefTitle: Air Pollution and Pregnancy acronym: PTB overallStatus: RECRUITING date: 2024-09-01 date: 2029-08-31 date: 2029-08-31 date: 2024-04-02 date: 2024-04-02 name: Queen Mary University of London class: OTHER name: University College London Hospitals briefSummary: We ar... |
We aim to develop and validate a deep learning model to predict the risk of preterm birth and other adverse pregnancy outcomes using data from EPIC electronic health records at University College London Hospital Trust (UCLH) for a cohort of 18000 patients. We will obtain corresponding data on exposure to ambient pollut... |
<|newrecord|> nctId: NCT06340958 id: CLE100-MDD-202 briefTitle: A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive Disorder acronym: SOLEO overallStatus: RECRUITING date: 2024-03-18 date: 2025-07-11 date: 2026-01-10 date: 2024-04-02 date: 2024-04-10 name: Cl... |
<|newrecord|> nctId: NCT06340945 id: S2023-761-01 briefTitle: The Outcomes of Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2027-12-31 date: 2029-12-31 date: 2024-04-02 date: 2024-04-02 name: Chinese PLA General Hospital class: OTHER briefSummary:... |
2. To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided thermal ablation in the treatment of benign thyroid nodules conditions: Thyroid Nodules studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count:... |
<|newrecord|> nctId: NCT06340932 id: CRS-119 (Pro00077191) briefTitle: Impact of Opioid Avoidance Protocol for ACL Reconstruction overallStatus: NOT_YET_RECRUITING date: 2024-03-28 date: 2024-08-15 date: 2024-10-01 date: 2024-04-02 date: 2024-04-02 name: Matthew Varacallo class: OTHER name: Pacira Biosciences briefSumm... |
The primary objective of this study is to evaluate the effect of the opioid avoidance protocol on opioid use in MME from POD0-7 after ACLR compared to the current standard of care pain management protocol. |
Secondary objectives are to: |
* evaluate the effects of an opioid avoidance protocol on the daily average NRS pain scores from POD0-7 |
* evaluate the effects of an opioid avoidance protocol on the daily worst NRS pain score from POD0-7 |
* evaluate the ability to recover opioid free through 7, 30, and 60 days |
* evaluate the QoR-15 scores on POD2 |
* assess the number of opioid prescriptions required by patients in the 60 day recover period |
* assess KOOS pain and symptom scales at 8 weeks post-operatively between groups. conditions: ACL Tear conditions: Post Operative Pain studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 40 type: ESTIMATED name: Iovera name: Celecoxib name: Acetaminophen name: Oxycodone name: Tramado... |
<|newrecord|> nctId: NCT06340919 id: 1406014978-241 briefTitle: Hearing Aid Algorithms for Sudden Sounds overallStatus: ENROLLING_BY_INVITATION date: 2024-02-21 date: 2024-09-30 date: 2025-05-31 date: 2024-04-02 date: 2024-04-02 name: Purdue University class: OTHER name: Oticon briefSummary: This study explores the imp... |
<|newrecord|> nctId: NCT06340906 id: 4573 id: UCI 23-29 type: OTHER domain: CFCCC briefTitle: Electroacupuncture in Symptom Management After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy overallStatus: NOT_YET_RECRUITING date: 2024-05-15 date: 2025-11-15 date: 2026-01-30 date: 2024-04-02 date: 202... |
<|newrecord|> nctId: NCT06340893 id: 76117 briefTitle: Exercise Training in Children With Communication Impairments overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-08-31 date: 2024-08-31 date: 2024-04-02 date: 2024-04-02 name: Marquette University class: OTHER name: University of Arizona briefSummary: Thi... |
All children (DLD and typically developing) will undergo communication, fine/gross motor and fitness testing. Children will be randomly assigned to participate in an exercise program (n =20) or to a restful play program (n = 20). Both programs will take place 3x/week for 6 weeks and children will only participate in on... |
Children in the exercise program will do activities to train cardiovascular fitness, agility, balance, strength, and endurance while children in the restful play condition will do things like play with legos and color. |
Researchers will compare changes in learning tasks and fitness levels for children (DLD and typically developing) who participated in the exercise program vs. restful play program. conditions: Developmental Language Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interve... |
<|newrecord|> nctId: NCT06340880 id: SAPB briefTitle: Serratus Anterior Plane Block, Ultrasound vs Anatomical Landmark Guided. overallStatus: RECRUITING date: 2024-03 date: 2024-05 date: 2024-05 date: 2024-04-02 date: 2024-04-02 name: Menoufia University class: OTHER briefSummary: This prospective, double-blinded rando... |
<|newrecord|> nctId: NCT06340867 id: 30723 briefTitle: Intraoral Scanner With and Without Orthodontic Brackets overallStatus: ACTIVE_NOT_RECRUITING date: 2023-09-01 date: 2024-03-24 date: 2024-04-01 date: 2024-04-02 date: 2024-04-02 name: Cairo University class: OTHER briefSummary: this study aim to evaluate the effect... |
<|newrecord|> nctId: NCT06340854 id: NN1436-7724 id: U1111-1292-6151 type: OTHER domain: World Health Organization (WHO) id: 2023-506084-34 type: OTHER domain: European Medical Agency (EMA) briefTitle: A Research Study to See How Switching From a Daily Basal Insulin to a New Weekly Insulin, Insulin Icodec, Helps in Red... |
<|newrecord|> nctId: NCT06340841 id: LEMURS SSI 24 briefTitle: LEMURS SSI: Evaluation of Behavioral Incentives acronym: LEMURSSI overallStatus: RECRUITING date: 2024-02-12 date: 2024-05-31 date: 2028-05-31 date: 2024-04-02 date: 2024-04-02 name: University of Vermont class: OTHER briefSummary: The goal of this substudy... |
<|newrecord|> nctId: NCT06340828 id: 2023-KY-186-01 briefTitle: Washed Microbiota Transplantation Alleviates Diabetic Gastrointestinal Motility Disorders: an Efficacy and Safety Study overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2027-07-20 date: 2027-07-20 date: 2024-04-02 date: 2024-04-03 name: The Second ... |
* The risk factors of diabetic gastrointestinal motility disorders in routine clinical data or biochemical tests. |
* The composition of gut microbiota in diabetic gastrointestinal motility disorders patients and potential pathogenic bacteria. |
* The efficacy of washing microbiota transplantation in the clinical treatment of diabetic gastrointestinal motility disorders patients and potential factors that may influence treatment outcomes. |
* The potential mechanisms of washing microbiota transplantation in treating diabetic gastrointestinal motility disorders patients. |
Participants will be collected fasting venous blood and random stool samples before treatment and at week 12 post-treatment, conducting scale assessments before treatment and at weeks 1, 4, and 12 post-treatment. conditions: Diabetic Gastroparesis conditions: Diabetic Gastropathy conditions: Diabetic Gastroenteropathy ... |
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