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<|newrecord|> nctId: NCT06340347 id: C5351010 briefTitle: A Study to Learn How the Body Processes the Study Medicine Called Osivelotor (PF-07940367) in People With Loss of Liver Function overallStatus: NOT_YET_RECRUITING date: 2024-04-24 date: 2026-02-05 date: 2026-02-05 date: 2024-04-01 date: 2024-04-01 name: Pfizer c... |
This study is seeking participants that are: |
* stable loss of liver function with mild or moderate severity |
* none of underlying conditions possibly affecting the study medicine being absorbed by the body |
All participants will receive one amount of Osivelotor by mouth before breakfast on the first day at the study clinic. A number of blood samples will be collected to understand how Osivelotor is changed and removed from the body. Participants will also have to undergo physical examination and other tests. This will hel... |
Participants will take part in the study for a maximum of 112 days. During this time, participants will have to stay onsite for 5 days. There will be 5 study visits at the study clinic. conditions: Liver Diseases studyType: INTERVENTIONAL phases: PHASE1 allocation: NON_RANDOMIZED interventionModel: PARALLEL interventio... |
<|newrecord|> nctId: NCT06340334 id: KY20240123-05 briefTitle: Efficacy and Safety of Tegoprazan Dual Therapy and Furazolidone-based Bismuth Quadruple Therapy for Helicobacter Pylori Eradication: A Prospective, Multicenter, Open-label, Randomized Controlled Clinical Study overallStatus: NOT_YET_RECRUITING date: 2024-03... |
<|newrecord|> nctId: NCT06340321 id: PBRC 2023-081 briefTitle: Impact of Metabolic Flexibility on Changes in Metabolic Health acronym: METPROS overallStatus: ENROLLING_BY_INVITATION date: 2024-06 date: 2025-01 date: 2025-01 date: 2024-04-01 date: 2024-04-03 name: Pennington Biomedical Research Center class: OTHER brief... |
In this study, the investigators will use the data from a study conducted approximately 16 years ago in healthy participants without obesity. Using the data already collected in that study, the metabolic flexibility of each participant will be calculated. To test the association between metabolic flexibility and the ch... |
<|newrecord|> nctId: NCT06340308 id: PARAF 986117570 briefTitle: Clinical Study With Berberine-based Food Supplement, Artichoke Extract, Phytosterols, Fenugreek and SelectSIEVE® OptiChol acronym: PARAF overallStatus: RECRUITING date: 2023-06-07 date: 2024-03 date: 2024-05 date: 2024-04-01 date: 2024-04-01 name: Univers... |
<|newrecord|> nctId: NCT06340295 id: 2023313 briefTitle: A Multicenter, Prospective Cohort Study of Preserved Ratio Impaired Spirometry(PRISm) in a Population overallStatus: RECRUITING date: 2023-09-01 date: 2026-05-31 date: 2026-05-31 date: 2024-04-01 date: 2024-04-01 name: Peking University First Hospital class: OTHE... |
<|newrecord|> nctId: NCT06340282 id: MOTOMED briefTitle: Immersive Virtual Reality and Physical Exercise on Cognitive and Functional Performance in Hospitalized Older Patients acronym: MOTOMED overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2025-04-01 date: 2024-04-01 date: 2024-04-03 name: Fu... |
The main objective of this study is to evaluate whether a cognitive stimulation intervention through immersive virtual reality, along with specific physical exercises, can improve the cognitive and physical function of hospitalized older patients. It is expected that this innovative intervention will have a positive im... |
Participants eligible for the study must be over 75 years old, have severe functional dependency upon hospital admission, and be willing to participate. Those with severe dementia or other terminal illnesses will be excluded. |
Participants will be randomly assigned to one of four study groups: a control group without intervention and three intervention groups, including viewing Spanish landscapes through virtual reality, performing specific physical exercises, or a combination of both interventions. |
At the end of the study, various aspects such as cognitive and physical function, mood, quality of life, muscle strength, and acceptance of virtual reality technology by patients will be evaluated. |
This study aims to provide new insights into the care of hospitalized older adults and explore innovative ways to improve their well-being during their hospital stay conditions: Disability Physical conditions: Cognition studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL intervention... |
<|newrecord|> nctId: NCT06340269 id: PJ2308-0025 briefTitle: Feasibility Pilot Study to Evaluate the Safety and Performance of the MEX-CD1 Medical Device in ACLF acronym: MexACLF overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-03 date: 2025-03 date: 2024-04-01 date: 2024-04-03 name: Mexbrain class: INDUSTRY ... |
* Is the device safe when used according to the instructions for use? |
* Does the device work as expected by removing the excess of free copper from the blood? |
Patients will receive 3 MEX-CD1 Slow Low volume CVVHD within 1 week. conditions: Acute on Chronic Liver Failure conditions: Multiple Organ Failure studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: Prospective, national, monocentric, single-arm, open label,... |
<|newrecord|> nctId: NCT06340256 id: IRB0000871253 briefTitle: Continuous Spinal Anesthesia Versus Epidural Anesthesia in Geriatric overallStatus: COMPLETED date: 2021-09-18 date: 2023-08-02 date: 2023-08-15 date: 2024-04-01 date: 2024-04-01 name: Assiut University class: OTHER briefSummary: 60 patients aged older than... |
<|newrecord|> nctId: NCT06340243 id: HODGKIN briefTitle: Risk Adapted Therapy of Hodgkin Lymphoma in Upper Egypt overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2026-04-01 date: 2024-04-01 date: 2024-04-01 name: Assiut University class: OTHER briefSummary: determine if radiotherapy could be sa... |
<|newrecord|> nctId: NCT06340230 id: BC-NEO-IIT-SHR-A1811-SHR1316 briefTitle: SHR-A1811 Alone or in Combination With Adebrelimab as Neoadjuvant Treatment in ER Positive/HER2 Low Breast Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2026-02-28 date: 2031-02-28 date: 2024-04-01 date: 2024-04-01 name: She... |
<|newrecord|> nctId: NCT06340217 id: WMT-GDP-RCT briefTitle: Washed Microbiota Transplantation for Diabetic Gastroparesis overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2029-01 date: 2029-07 date: 2024-04-01 date: 2024-04-17 name: The Second Hospital of Nanjing Medical University class: OTHER briefSummary: This ... |
<|newrecord|> nctId: NCT06340204 id: PKUPH-EWS-03 briefTitle: Weekly Irinotecan Liposomes in Recurrent or Refractory Ewing Sarcoma overallStatus: RECRUITING date: 2024-03-25 date: 2026-03-25 date: 2026-12-25 date: 2024-04-01 date: 2024-04-03 name: Peking University People's Hospital class: OTHER name: Peking University... |
<|newrecord|> nctId: NCT06340191 id: UJAPIlates1 briefTitle: Cueing and Pilates in Low Back Pain acronym: PIlatesuja overallStatus: COMPLETED date: 2023-05-02 date: 2024-02-20 date: 2024-02-26 date: 2024-04-01 date: 2024-04-01 name: University of Jaén class: OTHER briefSummary: The intervention involved two groups part... |
<|newrecord|> nctId: NCT06340178 id: 2024-00246 briefTitle: CT-guided Lung Biopsy Risk Optimization Method acronym: BROM-I overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2027-04-01 date: 2024-04-01 date: 2024-04-01 name: Insel Gruppe AG, University Hospital Bern class: OTHER briefSummary: The... |
<|newrecord|> nctId: NCT06340165 id: 2023-KS-151 briefTitle: A Real-world Efficacy and Safety Study of Amlotinib for HER2-negative Advanced Breast Cancer overallStatus: RECRUITING date: 2024-02-04 date: 2025-06 date: 2025-06 date: 2024-04-01 date: 2024-04-01 name: The First Hospital of Jilin University class: OTHER bri... |
<|newrecord|> nctId: NCT06340152 id: 808385 id: U01HG013189-01 type: NIH link: https://reporter.nih.gov/quickSearch/U01HG013189-01 briefTitle: Multi-Omics for Maternal Health After Preeclampsia acronym: MOM-Health overallStatus: RECRUITING date: 2023-12-20 date: 2028-12 date: 2028-12 date: 2024-04-01 date: 2024-04-01 n... |
<|newrecord|> nctId: NCT06340139 id: Riphah/RCRAHS-ISB/REC/01742 briefTitle: Vestibulo-Ocular Reflex for Balance and Stimming in Autism Spectrum Disorder overallStatus: RECRUITING date: 2024-03-20 date: 2024-07-20 date: 2024-08-20 date: 2024-04-01 date: 2024-04-01 name: Riphah International University class: OTHER brie... |
<|newrecord|> nctId: NCT06340126 id: REC/RCR & AHS/23/0567 briefTitle: Effects of Active Tissue Release Techniques on Groin Pain in 2nd Trimester of Pregnancy overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-09-20 date: 2024-10-05 date: 2024-04-01 date: 2024-04-01 name: Riphah International University clas... |
<|newrecord|> nctId: NCT06340113 id: REC/RCR & AHS/23/0108 NASHIA briefTitle: Mulligan and Mckenzie Exercises Alongwith Stabilization Exercises in Patients With Chronic Neck Pain overallStatus: RECRUITING date: 2023-11-20 date: 2024-06-01 date: 2024-06-01 date: 2024-04-01 date: 2024-04-03 name: Riphah International Uni... |
* Wether Mulligan is more effective or Mckenzie exercises along with stabilization exercises in the treatment of patients with chronic neck pain Group 1 will recieve Mulligan and stabilization exercises Group 2 will recieve Mckenzie and stabilization exercises conditions: Neck Pain studyType: INTERVENTIONAL phases: NA ... |
<|newrecord|> nctId: NCT06340100 id: REC/MS-PT/01832 briefTitle: Association of History of Concussion With Vestibular Impairment and Cognitive Function in Sports Athletes overallStatus: RECRUITING date: 2024-03-23 date: 2024-04-23 date: 2024-06-02 date: 2024-04-01 date: 2024-04-01 name: Riphah International University ... |
<|newrecord|> nctId: NCT06340087 id: 706014-3 briefTitle: Impact Hesperetin in Combination With Sucrose on Blood Glucose Regulation overallStatus: RECRUITING date: 2024-03-31 date: 2024-08-31 date: 2025-03-31 date: 2024-04-01 date: 2024-04-23 name: University of Vienna class: OTHER briefSummary: The aim of this cross-o... |
<|newrecord|> nctId: NCT06340074 id: STUDY00010282 briefTitle: Helping Educational Leadership Mobilize Evidence acronym: HELM overallStatus: COMPLETED date: 2022-08-28 date: 2023-06-01 date: 2023-06-07 date: 2024-04-01 date: 2024-04-01 name: University of Washington class: OTHER briefSummary: Many universal, evidence-b... |
<|newrecord|> nctId: NCT06340061 id: Qianyu Wu briefTitle: The Aim of This Study is to Investigate the Correlation Between the Severity of Glaucoma and Corneal Biomechanics as Well as Anterior Chamber Parameters. overallStatus: ACTIVE_NOT_RECRUITING date: 2022-10-20 date: 2024-12-31 date: 2024-12-31 date: 2024-04-01 da... |
<|newrecord|> nctId: NCT06340048 id: XC Liu briefTitle: Epicardial Injection of hiPSC-CMs to Treat Severe Chronic Ischemic Heart Failure overallStatus: RECRUITING date: 2023-09-05 date: 2024-09-05 date: 2025-03-05 date: 2024-04-01 date: 2024-04-01 name: Help Therapeutics class: INDUSTRY name: TEDA International Cardiov... |
<|newrecord|> nctId: NCT06340035 id: 20230901 briefTitle: Percutaneous Peripheral Nerve Stimulation of Gluteus Nerves to Improve Hip Strength and Power overallStatus: ACTIVE_NOT_RECRUITING date: 2023-09-01 date: 2024-04 date: 2024-06 date: 2024-04-01 date: 2024-04-01 name: Hospital Clinic of Barcelona class: OTHER brie... |
Does percutaneous stimulation of the superior and inferior gluteal nerves using ultrasound-guided needles enhance strength and power more effectively than transcutaneous stimulation through electrodes? |
Is the effectiveness of current delivery significantly different between percutaneous and transcutaneous methods when assessed with a linear encoder in a standarized hip extension exercise? |
Participants will: |
Be randomized into two groups: one undergoing ultrasound-guided percutaneous stimulation of the gluteal nerves (experimental group) and the other undergoing transcutaneous stimulation through electrodes (control group). |
The same stimulation protocol at 10 Hz frequency with the maximum muscle contraction evoked without pain will be performed in both groups. Then, the participants will undergo strength and power assessment before and after therapy administration using a linear encoder in a hip extension exercise. |
Researchers will compare the experimental group to the control group to see if the method of current delivery (percutaneous vs. transcutaneous) has a significant impact on the gains in strength and power. This comparison is based on the hypothesis that percutaneous delivery of current, guided by ultrasound, is more eff... |
<|newrecord|> nctId: NCT06340022 id: 2022-31 briefTitle: Pain and Anxiety Levels of Sleeperone Electronic Anesthesia System in Pediatric Patients overallStatus: COMPLETED date: 2023-03-13 date: 2023-10-02 date: 2023-11-15 date: 2024-04-01 date: 2024-04-01 name: Eskisehir Osmangazi University class: OTHER briefSummary: ... |
The aim of this study is to compare intraosseous anesthesia with SleeperOne® 5, a computer-assisted local anesthesia system, with conventional local anesthesia techniques in terms of pain and anxiety. conditions: Dental Anxiety conditions: Pain studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionMod... |
<|newrecord|> nctId: NCT06340009 id: REC/01743 briefTitle: MIME THERAPY vs MOTOR IMAGERY TECHNIQUE in Bell's Palsy overallStatus: RECRUITING date: 2024-03-22 date: 2024-08-22 date: 2024-08-25 date: 2024-04-01 date: 2024-04-01 name: Riphah International University class: OTHER briefSummary: Bell's palsy, characterized b... |
<|newrecord|> nctId: NCT06339996 id: KSVGH24-CT1-10 briefTitle: Male Supplements for Sperm Quality and Aging overallStatus: RECRUITING date: 2024-03-26 date: 2024-03-30 date: 2024-09-30 date: 2024-04-01 date: 2024-04-02 name: Kaohsiung Veterans General Hospital. class: OTHER briefSummary: This study investigates the ef... |
<|newrecord|> nctId: NCT06339983 id: REC/RCR & AHS/23/0566 briefTitle: Effects of Scar Mobilization Versus Myofascial Cupping Technique on Cesarean Scar overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-09-20 date: 2024-10-05 date: 2024-04-01 date: 2024-04-01 name: Riphah International University class: OTH... |
<|newrecord|> nctId: NCT06339970 id: REC/RCR & AHS/23/0199 iram briefTitle: Effects of Slider Versus Tensioners Nerve Gliding in Cervical Radiculopathy. overallStatus: RECRUITING date: 2023-11-23 date: 2024-06-01 date: 2024-06-01 date: 2024-04-01 date: 2024-04-01 name: Riphah International University class: OTHER brief... |
<|newrecord|> nctId: NCT06339957 id: STUDY00006394 briefTitle: Rheumatology Diet Study overallStatus: RECRUITING date: 2024-03-01 date: 2024-07-01 date: 2024-07-01 date: 2024-04-01 date: 2024-04-01 name: University of Central Florida class: OTHER briefSummary: This study aims to collect information on rheumatology pati... |
<|newrecord|> nctId: NCT06339944 id: REC/RCR& AHS/23/0198RubabTalib briefTitle: Effects of Sensory Motor Training and Kinesthetic Exercises in Knee Osteoarthritis. overallStatus: RECRUITING date: 2023-11-23 date: 2024-06-01 date: 2024-06-01 date: 2024-04-01 date: 2024-04-03 name: Riphah International University class: ... |
<|newrecord|> nctId: NCT06339931 id: REC/RCR &AHS/23/0181 briefTitle: Lumber Spine Mobilization and Spinal Traction on Lumber Radiculopathy. overallStatus: RECRUITING date: 2023-11-23 date: 2024-06-01 date: 2024-06-01 date: 2024-04-01 date: 2024-04-01 name: Riphah International University class: OTHER briefSummary: Lum... |
<|newrecord|> nctId: NCT06339918 id: REC/RCR & AHS/23/0570 briefTitle: Combined Effects of Kegel Exercises and 4-7-8 Breathing Technique in Primary Dysmenorrhea overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-09-20 date: 2024-10-05 date: 2024-04-01 date: 2024-04-03 name: Riphah International University cl... |
<|newrecord|> nctId: NCT06339905 id: 10840098-772.02-5564 briefTitle: The Effects of EndoActivator on Postoperative Pain and Root Canal Treatment Success overallStatus: COMPLETED date: 2022-01-01 date: 2022-08-31 date: 2023-08-31 date: 2024-04-01 date: 2024-04-01 name: Istanbul Medipol University Hospital class: OTHER ... |
<|newrecord|> nctId: NCT06339892 id: 2022-3.11/451 briefTitle: HCMV Breakthrough Infections During Letermovir Prophylaxis acronym: CMVbreak overallStatus: RECRUITING date: 2023-01-09 date: 2025-06 date: 2026-03 date: 2024-04-01 date: 2024-04-01 name: Foundation IRCCS San Matteo Hospital class: OTHER name: Ministero del... |
HCMV infection after transplantation is diagnosed by detection of HCMV DNA in blood. However, due to the peculiar mechanism of action of LTV, most episodes of HCMV DNA detection are caused by release in the blood stream of non-infectious HCMV DNA. |
In true episodes of productive infection, HCMV DNA in blood is present inside the virion and therefore is resistant to DNAse digestion. Conversely, when non-infectious free-floating HCMV DNA is released in the bloodstream, it will be degraded after treatment of plasma with DNAse and will not be detectable by real-time ... |
Researchers will compare determination of HCMV DNA in blood with or without previous digestion of non-infectious free-floating DNA with DNAse. |
In patients of the Control group HCMV DNA will be tested without DNAse digestion. If HCMV DNA is positive, patients will stop LTV prophylaxis and receive antiviral therapy with another drug. |
In patients of the Study group HCMV DNA will be tested after DNAse digestion. Only if HCMV DNA is positive after DNAse digestion, patients will stop LTV prophylaxis and receive antiviral therapy with another drug. |
The main aim of the study is to demonstrate that, by avoiding inappropriate antiviral therapy during LTV prophylaxis, transplant patients will suffer of lower antiviral-drug-related toxicity. A monitoring strategy able to identify true episodes of HCMV productive infection during LTV prophylaxis will lead to a lower ra... |
<|newrecord|> nctId: NCT06339879 id: IRB-2023-1071 briefTitle: Health Effects of Grain Foods in Adults overallStatus: RECRUITING date: 2024-01-18 date: 2026-06-30 date: 2026-12-31 date: 2024-04-01 date: 2024-04-04 name: Purdue University class: OTHER name: Grain Food Foundation briefSummary: This study will assess the ... |
<|newrecord|> nctId: NCT06339866 id: E16734702 briefTitle: The Effect of Two Different Video Showings on Pain and Anxiety in Children Undergoing Adenotonsillectomy overallStatus: ACTIVE_NOT_RECRUITING date: 2023-06-25 date: 2024-06-25 date: 2024-06-25 date: 2024-04-01 date: 2024-04-02 name: Zonguldak Bulent Ecevit Univ... |
Type of Research It is planned as a randomized controlled interventional type study to examine the effects of two different video presentations on pain and anxiety in children undergoing adenotonsillectomy. conditions: Pain After Adenotonsillectomy studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventio... |
<|newrecord|> nctId: NCT06339853 id: 1-2023-0023 briefTitle: Study of Efficacy of Digital Cognitive Behavioral Therapy With Wearable Device for Insomnia overallStatus: COMPLETED date: 2023-09-07 date: 2024-02-29 date: 2024-02-29 date: 2024-04-01 date: 2024-04-01 name: Yonsei University class: OTHER briefSummary: The pu... |
<|newrecord|> nctId: NCT06339840 id: 2024-036-01 briefTitle: The Impact of Lifestyle Intervention on Weight and Fertility in Obese Males overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-31 date: 2027-03-31 date: 2024-04-01 date: 2024-04-01 name: Third Affiliated Hospital of Zhengzhou University class: O... |
Previous systematic reviews have indicated an association between obesity and male factor infertility. In populations undergoing assisted reproductive technology (ART), some studies have shown a correlation between increased male BMI and adverse ART outcomes. Furthermore, the negative effects of obesity may also be tra... |
Currently, there is a lack of data on the impact of weight loss in obese men on fertility, and it is unclear which nutritional pattern in lifestyle interventions can more effectively control weight, improve semen quality, and address related endocrine issues in obese men, thereby improving reproductive treatment outcom... |
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