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Based on previous literature, we hypothesize that lifestyle interventions, particularly strict low-carbohydrate diets combined with lifestyle guidance, may offer greater health benefits for obese men. These benefits include effective weight loss, improvement in semen parameters, reproductive metabolic health, quality o... |
<|newrecord|> nctId: NCT06339827 id: 2023-102 briefTitle: ASk Questions in GYnecologic Oncology (ASQ-GYO) acronym: ASQ-GYO overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-02 date: 2026-02 date: 2024-04-01 date: 2024-04-01 name: Ira Winer class: OTHER briefSummary: The goal of this clinical trial is to determ... |
<|newrecord|> nctId: NCT06339814 id: 05/23-CE briefTitle: Eye Movement Desensitization and Reprocessing Group Treatment for Caregivers of Pediatric Brain Tumor Patients overallStatus: RECRUITING date: 2023-03-10 date: 2024-10 date: 2024-11-30 date: 2024-04-01 date: 2024-04-01 name: IRCCS Eugenio Medea class: OTHER brie... |
<|newrecord|> nctId: NCT06339801 id: HCJSM-24-193 briefTitle: Role of Mucosal Impedance Measurement for the Diagnosis of Gastroesophageal Reflux Disease overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-06-01 date: 2025-08-01 date: 2024-04-01 date: 2024-04-01 name: Hospital de Clinicas José de San Martín cl... |
Objectives |
The Main objectives of this study are to: |
1. Evaluate the diagnostic performance of mucosal impedance measurement. |
2. Investigate the mucosal impedance pattern in patients with and without GERD. |
Secondary objectives: |
1. Evaluate the correlation between the global mucosal impedance measurement vs the first 3cm measurement |
2. Evaluate the best probability score to distinguish between GERD and non-GERD Design Prospective, cross-sectional, and analytical study Study Design and Procedures The study will be conducted in the Gastroenterology Department of the Hospital de Clínicas José de San Martin, University of Buenos Aires, Argentina. Foll... |
<|newrecord|> nctId: NCT06339788 id: HD-MP-106 briefTitle: Pharmacokinetics of HD-P023 and Co-administration of Teneligliptin and Empagliflozin High in Healthy Volunteers overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-06 date: 2024-11 date: 2024-04-01 date: 2024-04-02 name: Handok Inc. class: INDUSTRY brief... |
<|newrecord|> nctId: NCT06339775 id: 2024318 briefTitle: Blinatumomab for Relapsed Acute B Lymphoblastic Leukemia After Transplantation overallStatus: RECRUITING date: 2023-09-01 date: 2026-12-31 date: 2027-06-30 date: 2024-04-01 date: 2024-04-01 name: Suping ZHANG class: OTHER briefSummary: B-ALL patients received reg... |
Anti-treatment was followed by DLI, and the second course was performed 1-2 months after DLI. |
Patients with positive MRD were treated with Blinatumomab 28μg×5-15 days, followed by DLI treatment. |
(MNC infusion is about 5×10\^7/kg\~1×10\^8/kg). Patients with hematologic recurrence were given Blinatumomab 9μg D1-4,11.66μg d5-7,28μg Starting from d8 （8 to 21 days in total）, followed by DLI treatment (infusion of MNC approximately 5×10\^7/kg\~1×10\^8/kg). Objective To observe and analyze the efficacy and side effec... |
<|newrecord|> nctId: NCT06339762 id: 2024/03-19 briefTitle: Self-Compassion Training Given to Relatives of Patients in Palliative Care overallStatus: RECRUITING date: 2024-02-13 date: 2024-03-13 date: 2024-04-13 date: 2024-04-01 date: 2024-04-01 name: Firat University class: OTHER briefSummary: The concept of self-comp... |
<|newrecord|> nctId: NCT06339749 id: [2024] Ethics Review NO.040 briefTitle: Pregnancy Outcomes in Normotensive VS stage1 Hypertension: a Prospective Observational Study overallStatus: NOT_YET_RECRUITING date: 2024-04-25 date: 2025-06-30 date: 2026-02-27 date: 2024-04-01 date: 2024-04-01 name: FANG HE class: OTHER brie... |
<|newrecord|> nctId: NCT06339736 id: 23815 briefTitle: Treatment Outcomes in Patients With Muscular Temporo-mandibular Joint Disorders overallStatus: RECRUITING date: 2022-01-10 date: 2025-01 date: 2025-12 date: 2024-04-01 date: 2024-04-01 name: University of Pisa class: OTHER briefSummary: The aim of the present study... |
<|newrecord|> nctId: NCT06339723 id: 2024/03-17 briefTitle: Pecha Kuka Method About Percutaneous Endoscopic Gastrostomy for Caregivers Who Care for Palliative Care Patients overallStatus: RECRUITING date: 2024-02-13 date: 2024-03-13 date: 2024-04-13 date: 2024-04-01 date: 2024-04-01 name: Firat University class: OTHER ... |
<|newrecord|> nctId: NCT06339710 id: U1111-1288-5508 briefTitle: Short Benznidazole Regimen for Chronic Phase Chagas Disease Patients acronym: Benlatino overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-01-30 date: 2026-10-30 date: 2024-04-01 date: 2024-04-01 name: Evandro Chagas Institute of Clinical Resea... |
The study will have 672 participants and will be carried out in four locations, Bolivia and Colombia. The objective is to analyze the efficacy and safety of new treatment regimens, evaluating the parasitological response in comparison with standard treatment. In addition, an economic assessment will be carried out to a... |
<|newrecord|> nctId: NCT06339697 id: 2022-KY-233 briefTitle: Short-term Effects of Bowel Preparation on Gut Microbiome in Patients Undergoing Endoscopic Colon Polypectomy overallStatus: COMPLETED date: 2022-12-01 date: 2023-06-30 date: 2023-06-30 date: 2024-04-01 date: 2024-04-01 name: Zhang Yanli class: OTHER briefSum... |
<|newrecord|> nctId: NCT06339684 id: 2021 0075257 briefTitle: HPV Immunological Markers of Cervical Persistent Infection and Oncogenesis acronym: HPVImmuno overallStatus: ACTIVE_NOT_RECRUITING date: 2023-03-08 date: 2026-03-08 date: 2026-03-08 date: 2024-04-01 date: 2024-04-03 name: Foundation IRCCS San Matteo Hospital... |
<|newrecord|> nctId: NCT06339671 id: PASSAGE briefTitle: Post-operative Complications and Smoking Habits in Colorectal Surgery acronym: PASSAGE overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-09-25 date: 2025-09-25 date: 2024-04-01 date: 2024-04-09 name: IRCCS Ospedale San Raffaele class: OTHER name: Ospe... |
<|newrecord|> nctId: NCT06339658 id: TAD-ICG briefTitle: ICG vs Blue Patent as a Tracer in the Performance of TAD in Patients With cN1 Breast Carcinoma After Neoadjuvant Chemotherapy overallStatus: RECRUITING date: 2021-01-01 date: 2026-01-01 date: 2026-01-01 date: 2024-04-01 date: 2024-04-15 name: Hospital Universitar... |
<|newrecord|> nctId: NCT06339645 id: P00003121 briefTitle: Intravesical Platelet-rich Plasma Injection in Patients With Interstitial Cystitis/Bladder-A Retrospective Study overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-05-22 date: 2024-12-31 date: 2024-04-01 date: 2024-04-01 name: Hualien Tzu Chi General... |
<|newrecord|> nctId: NCT06339632 id: AVAP-NG 3363 briefTitle: Effects of Transcutaneous Electrical Phrenic Nerve Stimulation and Transcutaneous Electrical Diaphragmatic Stimulation overallStatus: RECRUITING date: 2024-04-01 date: 2024-12-01 date: 2025-03-01 date: 2024-04-01 date: 2024-04-18 name: Hospital Sirio-Libanes... |
<|newrecord|> nctId: NCT06339619 id: SYSKY-2023-1262-02 briefTitle: Combination Immunotherapy of Adebrelimab With Apatinib and Tegafur for Immune Rechallenge Therapy in Esophageal Squamous Cell Carcinoma overallStatus: RECRUITING date: 2024-03-11 date: 2026-03-01 date: 2026-09-01 date: 2024-04-01 date: 2024-04-01 name:... |
<|newrecord|> nctId: NCT06339606 id: 4316 briefTitle: Pregnancy Repository acronym: PR overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-04-30 date: 2031-04-30 date: 2024-04-01 date: 2024-04-24 name: Sunnybrook Health Sciences Centre class: OTHER briefSummary: An essential part of clinical research is the a... |
In order to obtain high-quality biospecimens, they must be acquired serially, stored according to current standards, and matched with clinical information for maximum value. As such, the investigators would like to create a repository of biospecimens collected from pregnant patients who are seen at Mount Sinai Hospital... |
<|newrecord|> nctId: NCT06339593 id: 2023-0391 briefTitle: Regional Monitoring of CF Lung Disease overallStatus: RECRUITING date: 2024-01-05 date: 2028-01 date: 2028-01 date: 2024-04-01 date: 2024-04-01 name: Children's Hospital Medical Center, Cincinnati class: OTHER briefSummary: The main reason for this research stu... |
<|newrecord|> nctId: NCT06339580 id: 324456 briefTitle: Assessment of Volume-targeted Ventilation in Patients With Neuromuscular Disease acronym: VT-NMD overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-03 date: 2026-04 date: 2024-04-01 date: 2024-04-25 name: Guy's and St Thomas' NHS Foundation Trust class: OT... |
<|newrecord|> nctId: NCT06339567 id: 671_Hemo-PCOS briefTitle: Evaluation of the Venous Thrombotic Biological Profile of Different PCOS Phenotypes: French Cross-sectional Study acronym: Hemo-PCOS overallStatus: RECRUITING date: 2024-02-08 date: 2026-02-07 date: 2029-02-07 date: 2024-04-01 date: 2024-04-01 name: Fondati... |
based on three large studies, estimated the risk of VTE in women with PCOS after adjustment for obesity and hormone therapy. This risk was significantly higher compared with women without PCOS (pooled OR 1.89, CI95% 1.60-2.24). No study has looked specifically investigated the risk of VTE according to different PCOS ph... |
PCOS phenotypes. Intermediate markers of VTE risk are used in these situations. These markers are thrombin generation tests (notably ETP) and their sensitivity to activated protein C (nAPCsr) and thrombomodulin (nTMsr), as well as sex-hormone binding globulin (SHBG). conditions: Polycystic Ovary Syndrome studyType: INT... |
<|newrecord|> nctId: NCT06339554 id: 4806 briefTitle: Alectinib-induced Endocrine Toxicity acronym: TOSS-ALK overallStatus: COMPLETED date: 2018-10-12 date: 2023-10-30 date: 2023-10-30 date: 2024-04-01 date: 2024-04-01 name: Fondazione Policlinico Universitario Agostino Gemelli IRCCS class: OTHER briefSummary: The expe... |
<|newrecord|> nctId: NCT06339541 id: 029-FPO23 briefTitle: The ACC Preclinical Research Platform for Precision Oncology acronym: ACC Platform overallStatus: RECRUITING date: 2023-06-05 date: 2024-06-01 date: 2024-12-01 date: 2024-04-01 date: 2024-04-01 name: Fondazione del Piemonte per l'Oncologia class: OTHER name: Al... |
<|newrecord|> nctId: NCT06339528 id: EK-VPl421012021 briefTitle: Potential of Vojta's Reflex Locomotion as a Pre/Induction Method for Uterine Activity: a Pilot Study overallStatus: COMPLETED date: 2021-06-23 date: 2024-01-01 date: 2024-03-01 date: 2024-04-01 date: 2024-04-08 name: Faculty Hospital Kralovske Vinohrady c... |
<|newrecord|> nctId: NCT06339515 id: DuzceU-SBF-NYS-02 briefTitle: Teaching School Health Nursing Course With Universal Design Model overallStatus: NOT_YET_RECRUITING date: 2024-03-21 date: 2024-06-06 date: 2025-12-01 date: 2024-04-01 date: 2024-04-01 name: Duzce University class: OTHER briefSummary: The aim of this st... |
<|newrecord|> nctId: NCT06339502 id: Duzce-U-merve0002 briefTitle: The Effect of the Use of Jigsaw Technique on Nursing Students' Critical Article Reviews and Students' Opinions overallStatus: NOT_YET_RECRUITING date: 2024-03-22 date: 2024-04-22 date: 2024-05-24 date: 2024-04-01 date: 2024-04-01 name: Duzce University ... |
<|newrecord|> nctId: NCT06339489 id: 2022DZMEC-PG-34 briefTitle: The Bone Metabolism Characteristics of Premature Ovarian Insufficiency acronym: POI overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-01 date: 2025-02-01 date: 2024-04-01 date: 2024-04-02 name: Shi Yun class: OTHER briefSummary: Explore the... |
<|newrecord|> nctId: NCT06339476 id: Dilara ÜLGER ÖZBEK briefTitle: Exploring the Complex Links Between Menstrual Irregularity and Cellular Markers overallStatus: COMPLETED date: 2023-06-01 date: 2024-03-10 date: 2024-03-24 date: 2024-04-01 date: 2024-04-03 name: Cumhuriyet University class: OTHER briefSummary: A cross... |
<|newrecord|> nctId: NCT06339463 id: AAAU7985 briefTitle: Self-Distancing for Pediatric Anxiety and OCD overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-05 date: 2025-05 date: 2024-04-01 date: 2024-04-01 name: Columbia University class: OTHER briefSummary: Self-Distancing is a cognitive technique that involve... |
The study hypothesizes that Self-Distancing will produce greater increases in approach behaviors and greater decreases in anxiety severity than in the Classic Exposure. conditions: Anxiety Disorders conditions: Obsessive-Compulsive Disorder studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: ... |
<|newrecord|> nctId: NCT06339450 id: ExpoCF briefTitle: Real World Environmental Exposure Study With Healthy and Cystic Fibrosis Subjects acronym: ExpoCF overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-07-01 date: 2027-12-31 date: 2024-04-01 date: 2024-04-01 name: Centre Hospitalier Intercommunal Creteil ... |
<|newrecord|> nctId: NCT06339437 id: Adeel3 briefTitle: Enhanced Recovery After Cholecystectomy overallStatus: COMPLETED date: 2023-04-01 date: 2023-10-30 date: 2023-11-01 date: 2024-04-01 date: 2024-04-12 name: Children Hospital and Institute of Child Health, Lahore class: OTHER briefSummary: this study will be conduc... |
<|newrecord|> nctId: NCT06339424 id: 202400156A3 briefTitle: Atezolizumab and Bevacizumab With Photon Radiotherapy for Unresectable Hepatocellular Carcinoma acronym: PhotonAB overallStatus: NOT_YET_RECRUITING date: 2024-03-29 date: 2029-03-30 date: 2031-03-30 date: 2024-04-01 date: 2024-04-01 name: Chang Gung Memorial ... |
Radiation treatment (RT) is highly efficacious in controlling localized solid tumors and has become an integral component of the treatment algorithm for unresectable HCC. Importantly, a recent retrospective cohort described that RT combined with atezolizumab plus bevacizumab was associated with favorable median overall... |
Both atezolizumab/bevacizumab and X-ray RT are approved treatment methods for unresectable HCC by the U.S. and Taiwan Food and Drug Administration (FDA). The present phase II non-randomized trial aims to prospectively document the therapeutic efficacy, safety, and immunological responses in patients with unresectable H... |
<|newrecord|> nctId: NCT06339411 id: 202302239A3 briefTitle: Exploring Cerebrolysin in Late Thrombectomy for Stroke: Blood-brain Barrier Biomarkers and Imaging Insights overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-12-31 date: 2027-07-31 date: 2024-04-01 date: 2024-04-02 name: Chang Gung Memorial Hospit... |
Stroke is a leading cause of mortality and disability globally, with acute ischemic strokes(AIS) due to Large Vessel Occlusion (LVO) presenting significant treatment challenges. Mechanical thrombectomy (MT) has emerged as an effective intervention for AIS within an 8-hour window from symptom onset. However, the potenti... |
Methods: |
We conducted a multi-center, prospective, randomized study within the Chang Gung Memorial Hospital system in Taiwan, targeting 100 AIS patients eligible for MT beyond the traditional 8-hour window. Participants were randomized to receive either standard care or Cerebrolysin post-MT, initiated within 24 hours of stroke ... |
Results: |
The primary outcome will measure the proportion of patients achieving favorable functional outcomes (modified Rankin Scale 0-2) at 90 days. Secondary outcomes include the impact of Cerebrolysin on secondary hemorrhagic transformation, brain edema, mortality rates, and quality of life. The study aims to provide comprehe... |
Conclusion: |
By evaluating the role of Cerebrolysin in conjunction with MT, this study aims to extend the therapeutic window for AIS treatment, offering hope for improved outcomes for patients who would otherwise be ineligible for current reperfusion therapies. The findings may pave the way for new guidelines in stroke management, ... |
<|newrecord|> nctId: NCT06339398 id: 002-2023 briefTitle: To Evaluate the Dose-response Effects of a Defined Volume of Physical Exercise on the Change of Peripheral Biomarkers, Clinical Response and Brain Connectivity in Parkinson's Disease: a Prospective, Observational, Cohort Pilot Study acronym: METEX-PD overallStat... |
Thirty (N=30) participants will be consecutively enrolled and assigned to 2 groups: 1) Extensive Rehabilitation Group (exercise volume: 180 METs-min/week) or 2) Intensive Rehabilitation Group (exercise volume: 1350 METs-min/week). |
The primary objective is to evaluate the dose-response effects of two different rehabilitation settings, characterized by different workload (measured as energy expenditure), on blood BDNF levels. conditions: Parkinson Disease studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 30 ty... |
<|newrecord|> nctId: NCT06339385 id: KY 2020-153-02 briefTitle: Management of PADIS in Emergency Intensive Care Unit overallStatus: COMPLETED date: 2021-06-13 date: 2021-08-12 date: 2021-08-12 date: 2024-04-01 date: 2024-04-02 name: Capital Medical University class: OTHER name: Beijing Tiantan Hospital name: The First ... |
The investigators conducted a multicenter cross-sectional survey in mainland China, including a one-day point prevalence investigation and a questionnaire survey. The inclusion criteria encompassed all adult patients admitted to the participating emergency department intensive care units (EDICUs) during the on-site scr... |
<|newrecord|> nctId: NCT06339372 id: AP1912-30102 briefTitle: Perioperative Supplementation With Immunonutrition and Its Impact on Surgical Outcome and Pain in Oral Cavity or Mandibular Tumours overallStatus: COMPLETED date: 2023-02-01 date: 2023-08-01 date: 2023-08-01 date: 2024-04-01 date: 2024-04-02 name: Cairo Univ... |
<|newrecord|> nctId: NCT06339359 id: 2024-02-014 briefTitle: A Pilot Study to Develop a Behavior-based Screening Protocol for Early Diagnosis of Autism Spectrum Disorders overallStatus: RECRUITING date: 2024-03-01 date: 2025-03-31 date: 2025-03-31 date: 2024-04-01 date: 2024-04-01 name: Bundang CHA Hospital class: OTHE... |
<|newrecord|> nctId: NCT06339346 id: 29BRC24.0028 - PROMOT1 briefTitle: Analysis of Histopathological Factors Predictive of Lymph Node Involvement and Management Practices in pT1 Colorectal Cancers Treated by Primary Endoscopic Resection: a Retrospective Population-based Study (PROMOT1) acronym: PROMOT1 overallStatus: ... |
Among these, a number of lesions presenting pejorative criteria, notably histopathological, have a significant risk of lymph node invasion, and are therefore candidates for partial colectomy with lymph node dissection. Tumors deemed to be at low risk of lymph node involvement can be treated by endoscopy alone. |
It should be noted that further surgical intervention is not without comorbid consequences, and that a significant proportion of post-surgical surgical specimens are free of cancerous lesions. |
The aim of this study is therefore to analyze the current histopathological criteria predictive of lymph node invasion, in order to more accurately select candidates for surgical management. conditions: Colorectal Cancer conditions: Colorectal Adenocarcinoma studyType: OBSERVATIONAL observationalModel: OTHER timePerspe... |
<|newrecord|> nctId: NCT06339333 id: RRECB0523EC briefTitle: Evaluation of ACT Now GAIN Later overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-03-01 date: 2025-04-01 date: 2024-04-01 date: 2024-04-01 name: University College Dublin class: OTHER briefSummary: The goal of this Randomised Control Trial is to ... |
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