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<|newrecord|> nctId: NCT06336577 id: 2024/0003 briefTitle: Infectious and Non-infectious Lower Respiratory Diseases in Children With Down Syndrome Followed in Pediatric Pulmonology Consultations in Ile-de-France acronym: ARBT21 overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-31 date: 2024-12-31 date: 2... |
<|newrecord|> nctId: NCT06336564 id: 71168623.6.0000.5544 briefTitle: Microablative Radiofrequency in the Treatment of Urinary Symptoms Associated With Genitourinary Syndrome of Menopause overallStatus: NOT_YET_RECRUITING date: 2024-08 date: 2025-08 date: 2026-12 date: 2024-03-28 date: 2024-03-28 name: Centro de Atençã... |
<|newrecord|> nctId: NCT06336551 id: UniversityAmsterdam briefTitle: Acceptance and Commitment Therapy for Insomnia overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-01-26 date: 2026-01-26 date: 2024-03-28 date: 2024-03-29 name: University of Amsterdam class: OTHER briefSummary: Insomnia is a common sleep p... |
The main goal of this clinical trial is to test the efficacy of stand-alone ACT-I in adults with insomnia, compared to a waitlist control group. The second goal is to explore the potential working mechanisms of ACT-I, using network intervention analysis. |
Adults with insomnia will be randomized to an ACT-I or waitlist group. Both the ACT-I treatment and waiting period span 7 weeks. Assessments take place at baseline (pre), after 4 weeks (mid), and after 8 weeks (post), followed by a 3- and 6-month follow-up for the ACT-I group. |
The main questions this RCT aims to answer are: |
* Is ACT-I superior to a waitlist control group in improving insomnia severity (primary outcome) in addition to sleep diary measures, anxiety, depression, general mental health, and sleep-related quality of life (secondary outcomes)? |
* How do networks of insomnia symptoms or potential treatment processes (i.e., psychological (in)flexibility, sleep-related arousal, dysfunctional cognitions, and sleep-related safety behaviors) develop during and following ACT-I? conditions: Insomnia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interven... |
<|newrecord|> nctId: NCT06336538 id: CASE1124 briefTitle: Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2025-01-31 date: 2025-01-31 date: 2024-03-28 date: 2024-03-29 name: Case Comprehensive Cancer Center class: OTHER bri... |
<|newrecord|> nctId: NCT06336525 id: 2023P001895 id: R01HL164462 type: NIH link: https://reporter.nih.gov/quickSearch/R01HL164462 briefTitle: Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities. overallStatus: NOT_YET_RECRUITING date: 202... |
<|newrecord|> nctId: NCT06336512 id: RC.28.1.2024 briefTitle: Trimester Sequential Estimation of Serum Zonulin as a Predictor of Gestational Diabetes Mellitus overallStatus: COMPLETED date: 2023-01-15 date: 2023-07-01 date: 2023-10-01 date: 2024-03-28 date: 2024-03-28 name: Benha University class: OTHER briefSummary: G... |
<|newrecord|> nctId: NCT06336499 id: TREC2023-KY107 briefTitle: Risk Stratification of Orbital Tumors Based on MRl and Artificial Intelligence overallStatus: COMPLETED date: 2012-01-01 date: 2022-10-31 date: 2023-12-31 date: 2024-03-28 date: 2024-03-29 name: Beijing Tongren Hospital class: OTHER briefSummary: Orbital t... |
<|newrecord|> nctId: NCT06336486 id: BalikesirU-FTR-BG-01 briefTitle: the Effectiveness of Intermittent Pneumatic Compression on Neuropathic Pain in Patients With Diabetic Polyneuropathy overallStatus: COMPLETED date: 2018-12-04 date: 2020-02-01 date: 2020-02-01 date: 2024-03-28 date: 2024-04-01 name: Busra Gunes class... |
<|newrecord|> nctId: NCT06336473 id: 2023-A02097-38 briefTitle: Evaluation of the Effects of Cross Linking on the Biomechanical Characteristics of Skin Samples From Patients With Classic or Hypermobile Ehlers-Danlos Syndrome acronym: SEDSKIN overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2025... |
<|newrecord|> nctId: NCT06336460 id: 2023-537 briefTitle: PENG vs. FIC Blocks in Hip Fractures in the ED overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2026-04-01 date: 2024-03-28 date: 2024-03-28 name: Orange Park Medical Center class: OTHER briefSummary: This study is a prospective, randomi... |
<|newrecord|> nctId: NCT06336447 id: STU00220295 briefTitle: VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain overallStatus: RECRUITING date: 2024-01-12 date: 2026-12-31 date: 2027-02-28 date: 2024-03-28 date: 2024-03-28 name: Northwestern University class: OTHER briefSummary: This study wil... |
The goals of the study is to determine the relative efficacy of virtual reality as a distraction modality when used as an adjuvant to procedural sedation compared to sedation alone for procedure related pain. To assess procedural satisfaction, and 1-month pain and functional outcomes.To explore whether virtual reality ... |
<|newrecord|> nctId: NCT06336434 id: IMPAACT 2040 briefTitle: CREATE - Cabotegravir & Rilpivirine Antiretroviral Therapy in Pregnancy overallStatus: NOT_YET_RECRUITING date: 2024-09-24 date: 2026-12-24 date: 2026-12-24 date: 2024-03-28 date: 2024-03-28 name: National Institute of Allergy and Infectious Diseases (NIAID)... |
<|newrecord|> nctId: NCT06336421 id: Şuletuvanç briefTitle: The Effect of Virtual Reality Application on Perceived Anxiety and Vital Signs in Primiparous overallStatus: COMPLETED date: 2022-11-01 date: 2023-06-15 date: 2024-03-22 date: 2024-03-28 date: 2024-03-28 name: Ataturk University class: OTHER briefSummary: Purp... |
<|newrecord|> nctId: NCT06336408 id: B2023-370R briefTitle: The SLEEP-CARE Study overallStatus: RECRUITING date: 2024-02-01 date: 2025-12-31 date: 2025-12-31 date: 2024-03-28 date: 2024-03-28 name: Shanghai Zhongshan Hospital class: OTHER briefSummary: Sleep disorder is common in ICU patients, such as reduced sleep tim... |
<|newrecord|> nctId: NCT06336395 id: 2019/00888 briefTitle: Ma-Spore ALL 2020 Study overallStatus: RECRUITING date: 2020-03-04 date: 2030-03 date: 2030-03 date: 2024-03-28 date: 2024-03-28 name: National University Hospital, Singapore class: OTHER briefSummary: The primary objective of this trial is to improve the over... |
<|newrecord|> nctId: NCT06336382 id: 23-0874 id: 1R21MH135148 type: NIH link: https://reporter.nih.gov/quickSearch/1R21MH135148 briefTitle: Tau Biomarkers in Late-onset Psychosis (LOP) overallStatus: RECRUITING date: 2024-02-16 date: 2026-12-31 date: 2027-06-30 date: 2024-03-28 date: 2024-03-28 name: Jeremy Koppel clas... |
<|newrecord|> nctId: NCT06336369 id: 1713/2023 briefTitle: Brown Adipose Tissue Activity in Gilbert's Syndrome overallStatus: RECRUITING date: 2024-03-06 date: 2027-01-15 date: 2027-01-15 date: 2024-03-28 date: 2024-03-28 name: Medical University of Vienna class: OTHER name: University of Vienna name: Griffith Universi... |
1. the link between bilirubin metabolism and metabolic health. |
2. energy metabolism and body composition in individuals with Gilbert's syndrome and control subjects |
3. brown adipose tissue activity in Gilbert's syndrome and healthy controls. |
Participants will undergo the following investigations: |
1. cold exposure |
2. PET-CT imaging with 18-F-FDG |
3. MRI imaging of liver, abdominal fat and muscle |
4. blood sampling |
5. indirect calorimetry |
6. bioelectrical impedance analysis |
7. infrared thermography |
Researchers will compare individuals with GS and control subjects in terms of metabolic health, body composition and BAT activity. conditions: Gilbert Syndrome studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 80 type: ESTIMATED name: analyzing brown adipose tissue, body comp... |
<|newrecord|> nctId: NCT06336356 id: D6970C00011 briefTitle: A Study to Evaluate Cortisol Reserve in Response to Adrenocorticotropic Hormone (ACTH) Stimulation Test Following Baxdrostat Treatment Compared to Placebo in Participants With Uncontrolled Hypertension overallStatus: NOT_YET_RECRUITING date: 2024-05-13 date: ... |
<|newrecord|> nctId: NCT06336343 id: STUDY-23-01698 briefTitle: Bimekizumab in Plaque Psoriasis overallStatus: RECRUITING date: 2024-03 date: 2025-10-31 date: 2025-10-31 date: 2024-03-28 date: 2024-03-28 name: Icahn School of Medicine at Mount Sinai class: OTHER name: UCB Pharma name: Psoriasis Treatment Center of Cent... |
<|newrecord|> nctId: NCT06336330 id: D1699R00050 briefTitle: Real-world Study on Dapagliflozin Usage in Patients With Heart Failure (HF) in Germany acronym: EvolutionHF-DE overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2026-09-30 date: 2026-09-30 date: 2024-03-28 date: 2024-03-28 name: AstraZeneca class: INDU... |
<|newrecord|> nctId: NCT06336317 id: ELIMINATE-2024 briefTitle: Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE acronym: ELIMINATE overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-12 date: 2027-12 date: 2024-03-28 date: 2024-03-28 name: Region Örebro County class: ... |
Does influenza vaccination reduce arterial inflammation as measured by CCTA at week 8 after percutaneous coronary intervention (PCI) in comparison to baseline? Does influenza vaccination modulate systemic inflammation as measured by blood biomarkers and in-vitro challenge tests at week 8 after PCI in comparison to base... |
<|newrecord|> nctId: NCT06336304 id: NXTPMCF-01 briefTitle: NXT Post-Market Clinical Follow-up overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-11 date: 2025-12 date: 2024-03-28 date: 2024-03-28 name: Laborie Medical Technologies Inc. class: INDUSTRY briefSummary: NXT Urodynamics System Post-Market Clinical F... |
<|newrecord|> nctId: NCT06336291 id: PH-L19TNFLOM-01/23 briefTitle: A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence acronym: GLIOSTELLA overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-06 date: 2026-06 date: 2024-03-28 date: 2024-03-28 name: Philoge... |
<|newrecord|> nctId: NCT06336278 id: 19/03/2024 briefTitle: Relationship Between Central Sensitization and Kinesiophobia in Knee Osteoarthritis overallStatus: COMPLETED date: 2022-10-01 date: 2023-10-01 date: 2023-12-01 date: 2024-03-28 date: 2024-04-22 name: Selda Sarıkaya class: OTHER briefSummary: Objective: The kne... |
Materials and Methods: Forty-two patients with knee OA and 42 healthy subjects participated in our study. Demographic data, body mass index, habits, comorbidities, medications of participants and disease duration and radiographic grade of knee OA patients were recorded. VAS was used to assess the severity of pain and W... |
<|newrecord|> nctId: NCT06336265 id: Diaphragm ultrasound briefTitle: Diaphragmatic Ultrasound to Predict the Therapeutic Effect of High-flow Nasal Cannula Oxygen Therapy overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-12-31 date: 2024-12-31 date: 2024-03-28 date: 2024-03-28 name: Xingui Dai class: OTHER ... |
<|newrecord|> nctId: NCT06336252 id: F-23059441 briefTitle: Technology Assisted Nudging to Increase Physical Activity Among Hospitalised Medical Patients acronym: SENS4ME overallStatus: RECRUITING date: 2024-04 date: 2025-12-20 date: 2026-06-20 date: 2024-03-28 date: 2024-03-28 name: Bispebjerg Hospital class: OTHER na... |
Hypothesis Patients hospitalised for medical disease will increase their physical activity level during hospitalisation and 3 months after discharge through visual feedback and motivational intervention from a new mobile technology. conditions: COPD conditions: Heart Failure conditions: Parkinson Disease conditions: Ar... |
<|newrecord|> nctId: NCT06336239 id: KS2023097 briefTitle: PrevaLence of Albuminuria in Patients With CARdiovascular Disease and Type 2 Diabetes Mellitus in China: a National Cross-sectional Study acronym: PLACARD overallStatus: RECRUITING date: 2023-12-21 date: 2024-06-30 date: 2024-12-30 date: 2024-03-28 date: 2024-0... |
<|newrecord|> nctId: NCT06336226 id: BB AVF one stage vs two stage briefTitle: Brachio Basilic Arterio Venous Fistula One Stage vs Two Stage overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-04 date: 2025-05 date: 2024-03-28 date: 2024-04-05 name: Assiut University class: OTHER briefSummary: The aim of this wo... |
<|newrecord|> nctId: NCT06336213 id: 20240306 briefTitle: Antibacterial Tactics Based on Presepsin Level in Thoracic Aorta Surgery Patients overallStatus: RECRUITING date: 2024-02-19 date: 2024-11-01 date: 2024-12-15 date: 2024-03-28 date: 2024-03-28 name: Petrovsky National Research Centre of Surgery class: OTHER brie... |
<|newrecord|> nctId: NCT06336200 id: Karabuk-006 briefTitle: Knee Osteoarthritis and Kinesiophobia overallStatus: RECRUITING date: 2024-01-01 date: 2024-04-30 date: 2024-05-30 date: 2024-03-28 date: 2024-04-05 name: Karabuk University class: OTHER briefSummary: Kinesiophobia after total knee arthroplasty is an importan... |
<|newrecord|> nctId: NCT06336187 id: UPO 2020 02 briefTitle: European Active Surveillance of Renal Cell Carcinoma Study (EASE RCC Study) acronym: EASE overallStatus: RECRUITING date: 2018-06-01 date: 2024-12 date: 2030-12 date: 2024-03-28 date: 2024-04-10 name: Azienda Ospedaliero Universitaria Maggiore della Carita cl... |
The primary endpoint is overall survival. The Secondary endpoints are tumor growth rate, progression rate, cancer-specific survival, progression-free survival, identification of clinical and pathological variables and molecular and genetic markers that correlate with growth rate and progression. |
The main question it aims to answer is: patients with RCC (less than 4 cm) diagnosis can be managed with active surveillance instead treated with invasive curative procedure? For all participants a percutaneous biopsy of the renal mass will be arranged in all cases to histologically confirm the diagnosis of RCC (unless... |
Then, all patients will be under active surveillance, which is defined as the initial monitoring of tumor size by serial abdominal imaging (US, CT, or MRI) Follow-up visits will be scheduled 3 (optional) and 6 months after diagnosis, every 6 months up to 3 years and yearly thereafter. A follow-up visit will also be car... |
Follow-up percutaneous biopsies of the renal tumor are not mandatory, but can be performed when considered clinically important. conditions: Renal Cell Carcinoma studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 400 type: ESTIMATED name: active surveillance name: molecular investig... |
<|newrecord|> nctId: NCT06336174 id: Anhui-SIA-cohort briefTitle: Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study overallStatus: RECRUITING date: 2022-11-01 date: 2025-12-31 date: 2026-12-31 date: 2024-03-28 date: 2024-04-02 name: Anhui Medical University... |
<|newrecord|> nctId: NCT06336161 id: ESPB versus CEI briefTitle: Comparison Between Ultrasound-Guided Erector Spinae Plane Block Versus Ultrasound-Guided Caudal Injection overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-01 date: 2025-05-01 date: 2024-03-28 date: 2024-03-28 name: Al-Azhar University clas... |
The methods of access for epidural injections are characterized as transforaminal, interlaminar, or caudal. Caudal epidural injections (CEI) are often utilized as a diagnostic or therapeutic tool in a range of lumbosacral-originating spinal pain problems, and they are especially useful in patients with complicated lumb... |
<|newrecord|> nctId: NCT06336148 id: ACTM-838-01 briefTitle: A Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid Tumors overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-01 date: 2026-07 date: 2024-03-28 date: 2024-03-28 name: Actym Therapeutics, Inc. class: INDUSTRY briefSummary: This is a first i... |
<|newrecord|> nctId: NCT06336135 id: 23-001 briefTitle: Reduction in Symptoms After Laser Therapy With Acorn aHFS overallStatus: ENROLLING_BY_INVITATION date: 2024-03-25 date: 2025-03 date: 2025-12 date: 2024-03-28 date: 2024-03-28 name: Acorn Biolabs Inc. class: INDUSTRY briefSummary: This study evaluates the severity... |
<|newrecord|> nctId: NCT06336122 id: 83904_1 id: R01DK135885-01 type: NIH link: https://reporter.nih.gov/quickSearch/R01DK135885-01 briefTitle: OASIS: Peer Support for T2DM in Appalachia (Peer Participant) acronym: OASIS overallStatus: RECRUITING date: 2024-02-21 date: 2025-12-31 date: 2026-03-31 date: 2024-03-28 date:... |
Are peer coaching models effective at promoting Type 2 Diabetes Mellitus self-management? |
If effective, which facets of the peer model are most effective? Peer coaches will Undergo peer coach training. |
Reach out to peer participants on a weekly/biweekly time frame to discuss self-management and goal setting. |
Retain records of contact, topics discussed, and general notes on interactions. Researchers will compare differences in the frequency of contact, as well as how peer coaches were matched to peer participants to see if efficacy of the intervention is altered between groups. conditions: Diabetes Mellitus, Type 2 studyTyp... |
<|newrecord|> nctId: NCT06336109 id: N-20220063-3 briefTitle: Fragmented Sleep, Pain, and Biomechanics overallStatus: RECRUITING date: 2024-01-26 date: 2024-12-31 date: 2024-12-31 date: 2024-03-28 date: 2024-04-03 name: Aalborg University class: OTHER briefSummary: This interventional study aims to test the effects of ... |
1) Does sleep fragmentation increase experimental knee and shoulder pain and what are the underlying mechanisms? |
Participants will receive two injections a) Hypertonic saline (painful) in the knee and b) hypertonic saline (painful) in the upper arm. conditions: Pain conditions: Healthy conditions: Sleep Disturbance studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: BASIC_SCIENCE ma... |
<|newrecord|> nctId: NCT06336096 id: VX23-548-017 briefTitle: A Study to Evaluate the Relative Bioavailability and Food Effect of a New Tablet Formulation and Strength of Suzetrigine overallStatus: RECRUITING date: 2024-03-28 date: 2024-10 date: 2024-10 date: 2024-03-28 date: 2024-04-26 name: Vertex Pharmaceuticals Inc... |
<|newrecord|> nctId: NCT06336083 id: RC31/23/0618 briefTitle: Familial Form of Carotid Web: a Doppler Ultrasound Study acronym: Family-WEB overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2026-06 date: 2026-06 date: 2024-03-28 date: 2024-04-11 name: University Hospital, Toulouse class: OTHER briefSummary: There is... |
<|newrecord|> nctId: NCT06336070 id: 2024-FIS-3251696 id: CIACIF/2022/368 type: OTHER_GRANT domain: Regional Ministry of Education, Universities and Employment - Generalitat Valenciana briefTitle: Metabolic Flexibility and Autonomic Control After Muscle Power vs Metabolic Power Training in Postmenopausal Oncological Wo... |
<|newrecord|> nctId: NCT06336057 id: RC31/23/0408 briefTitle: Mentalizating in Adults Suffering From Narcolepsy Type 1. acronym: NARCOMENTAL overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-04 date: 2025-12 date: 2024-03-28 date: 2024-03-28 name: University Hospital, Toulouse class: OTHER briefSummary: The ma... |
<|newrecord|> nctId: NCT06336044 id: Taufiller/22 briefTitle: Pre-marketing Clinical Trial to Evaluate the Safety and Efficacy of the Filler of Hyaluronic Acid Recombinant Collagen overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-11 date: 2025-01 date: 2024-03-28 date: 2024-03-28 name: Taumedika s.r.l. class:... |
<|newrecord|> nctId: NCT06336031 id: 30002163 briefTitle: Impact of Blood Phobia on Fainting Susceptibility overallStatus: RECRUITING date: 2024-03-30 date: 2024-12 date: 2025-02 date: 2024-03-28 date: 2024-04-17 name: Simon Fraser University class: OTHER briefSummary: The primary purpose of this study is to characteri... |
<|newrecord|> nctId: NCT06336018 id: NN7535-7703 id: U1111-1289-2466 type: OTHER domain: World Health Organization (WHO) briefTitle: A Research Study on Etavopivat in Participants With and Without Liver Disease overallStatus: NOT_YET_RECRUITING date: 2024-03-29 date: 2025-07-04 date: 2025-07-04 date: 2024-03-28 date: 2... |
<|newrecord|> nctId: NCT06336005 id: NN6022-7683 briefTitle: A Study to See How Safe a New Medicine (NNC6022-0001) is in Healthy People overallStatus: RECRUITING date: 2024-03-28 date: 2024-10-17 date: 2024-10-17 date: 2024-03-28 date: 2024-04-15 name: Novo Nordisk A/S class: INDUSTRY briefSummary: The study is testing... |
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