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Consequently, ADMR is undertaking an additional, single centre RCT which will compare the acute physiological responses to low load resistance training with and without the addition of blood flow restriction. Specifically, this study will elucidate the effect of twice daily blood flow restriction training on measures o... |
<|newrecord|> nctId: NCT06334211 id: FP-020C-23-001 briefTitle: Safety, Tolerability, and Pharmacokinetics, of Single and Multiple Ascending Doses of FP-020 in Healthy Adult Volunteers overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2024-09-30 date: 2025-01-31 date: 2024-03-27 date: 2024-04-11 name: Foresee Ph... |
<|newrecord|> nctId: NCT06334198 id: Naldemedine_OIBD id: 2023-507744-36-00 type: CTIS briefTitle: The Effect of Naldemedine on Opioid-induced Bowel Dysfunction overallStatus: RECRUITING date: 2024-03-12 date: 2025-03 date: 2025-03 date: 2024-03-27 date: 2024-03-28 name: Asbjørn Mohr Drewes class: OTHER briefSummary: O... |
<|newrecord|> nctId: NCT06334185 id: pVax briefTitle: Evaluation of Vaccination for Streptococcus Pneumoniae in Adults With an Episode of Invasive Pneumococcal Infection. acronym: pVax overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-07-01 date: 2024-07-01 date: 2024-03-27 date: 2024-03-28 name: Azienda Os... |
However, there are no data available in Italy on vaccination coverage in these population categories and above all the vaccination rates in patients who have a history of an episode of invasive pneumococcal infection are not known. The aim of the study is to measure how many patients are vaccinated for S. pneumoniae af... |
<|newrecord|> nctId: NCT06334172 id: H-23071221 briefTitle: The Role of Oxytocin in Regulating Blood Glucose acronym: GLOXY-1 overallStatus: RECRUITING date: 2024-01-01 date: 2026-12-31 date: 2026-12-31 date: 2024-03-27 date: 2024-04-04 name: University Hospital, Gentofte, Copenhagen class: OTHER briefSummary: Investig... |
<|newrecord|> nctId: NCT06334159 id: PER-ECL-2019-08 briefTitle: Guided Bone Regeneration Using Fixed vs Non-Fixed Resorbable Collagen Membranes overallStatus: RECRUITING date: 2020-11-05 date: 2025-07-20 date: 2027-07-20 date: 2024-03-27 date: 2024-03-27 name: Universitat Internacional de Catalunya class: OTHER briefS... |
<|newrecord|> nctId: NCT06334146 id: UNLV-2023-62 briefTitle: Tap Dance for Adults With Lower Limb Amputation overallStatus: RECRUITING date: 2024-03-04 date: 2025-05 date: 2025-05 date: 2024-03-27 date: 2024-03-27 name: University of Nevada, Las Vegas class: OTHER briefSummary: The goal of this study is to determine w... |
There is a lack of research investigating therapeutic interventions for people with lower limb amputation (LLA). Tap dance encourages balance and novel movements of the limbs, while providing auditory feedback from the feet that provide information about the foot's contact with the ground, which may help prosthesis use... |
Participants will be asked to: |
* come to 1 hour dance classes, once per week, for 8 weeks. |
* do mobility tests before and after the program |
* complete questionnaires before, during and after the program. The total time for participation is approximately 8-10 weeks. conditions: Amputation; Traumatic, Leg, Lower studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 6 type: ESTIMATED... |
<|newrecord|> nctId: NCT06334133 id: TTP399-302 briefTitle: Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes acronym: CATT1 overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-06 date: 2026-03 date: 2024-03-27 date: 2024-04-01 name: vTv Therapeutics class: INDUSTRY briefSummary: This is a Phase 3 trial of ... |
<|newrecord|> nctId: NCT06334120 id: 20654 briefTitle: An Observational Study to Learn More About the Safety of Darolutamide in Men With Prostate Cancer in Korea overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2025-09-30 date: 2026-03-31 date: 2024-03-27 date: 2024-03-27 name: Bayer class: INDUSTRY briefSummar... |
This study looks at the safety of the study drug, darolutamide, in Korean patients with nmCRPC or mHSPC. Darolutamide is currently available for doctors to prescribe to men with nmCRPC or mHSPC. It works by attaching to the special molecules called androgen receptors (AR) within prostate cells and blocks hormones calle... |
To learn more about the safety of Darolutamide, the researchers will study whether the participants have adverse events. An adverse event is any medical problem that a participant has during a study. Doctors keep track of all adverse events that happen in studies, even if they do not think the adverse events might be r... |
During this study, the researchers will collect information from the medical records of patients who have been prescribed darolutamide by their doctors. |
Each participant will be in this study for 1 year. The whole study will last about 6 years. During this time, the participants will visit their doctor every 2 to 4 months as part of their usual care. At these visits, the doctors will do scans to check the patients' cancer and take blood samples. The patients will answe... |
<|newrecord|> nctId: NCT06334107 id: 24AIREA1191995 briefTitle: Mitochondrial DNA Signatures of Poor Aerobic Exercise Trainability in Young Adults Born Preterm overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-12-01 date: 2025-12-31 date: 2024-03-27 date: 2024-03-27 name: Texas Tech University class: OTHER ... |
One likely explanation for poor exercise trainability and increased heart disease risk in young adults born very preterm is the effect of the early birth on the major energy producers in all our cells: Mitochondria. During late-stage gestation, mitochondria change from relying on sugar as a major fuel source to fat. Un... |
To date, there is not a way to help young adults born preterm improve their fitness level. One likely target is in the mitochondria: it's DNA. Mitochondrial DNA helps determine how mitochondria function and can be damaged under stress. Our goal in this proposed work is to determine the role of mitochondrial DNA in mito... |
Questions: |
1. Are there mitochondrial DNA markers linked to mitochondrial dysfunction and poor exercise trainability in young adults very born preterm? |
2. Do mitochondrial DNA in young adults born very preterm respond differently to aerobic exercise training than those born at term? |
The investigators expect this work will show mitochondrial DNA changes linked to mitochondrial dysfunction and poor trainability, which can be used for future targets to improve health. This work supports AHA mission by helping to identify a marker in individuals born very preterm linked to their higher heart disease r... |
<|newrecord|> nctId: NCT06334094 id: IRB-23-486 id: IM047-1054 type: OTHER_GRANT domain: Bristol Myers Squibb briefTitle: Assessing the Cognitive Benefits of Ozanimod and Their Brain-Biomarkers in MS overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2028-03-31 date: 2028-05-31 date: 2024-03-27 date: 2024-03-27 n... |
<|newrecord|> nctId: NCT06334081 id: A02040230S briefTitle: Different Surgical Drilling Protocols in Posterior Maxilla overallStatus: ACTIVE_NOT_RECRUITING date: 2023-06-29 date: 2023-12-30 date: 2024-06-30 date: 2024-03-27 date: 2024-03-27 name: Mansoura University class: OTHER briefSummary: Sixteen dental implants in... |
<|newrecord|> nctId: NCT06334068 id: MS.24.03.2725 briefTitle: SHOrt-term Glycemic Control for Reducing Post-SURGical Complications acronym: Surg-ShoGR overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-09 date: 2024-10 date: 2024-03-27 date: 2024-03-27 name: Mansoura University class: OTHER briefSummary: Perio... |
There are no studies that confirm that postponing elective surgery improves patient outcomes. Likewise, no prospective trials have studied whether short-term glycemic control reduces postoperative complications and unnecessary patient delays in elective surgeries. |
Consequently, we designed a randomized controlled trial to investigate the effects of short-term glycemic control before major abdominal surgery on postoperative morbidity and mortality. conditions: Diabetes conditions: Uncontrolled Diabtetes studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel... |
1. Short-term glycemic control group: |
Patients will be admitted to the hospital for 2-3 days before surgery. During this pilot study, patients will be admitted to the intermediate care unit to monitor and control preoperative blood glucose. We aim to maintain moderate glucose control (140 - 180 mg/dl) using basal-bolus insulin protocol plus correctional... |
2. Standard-of-care group: Patients will be admitted the day before surgery with the usual patient treatment. primaryPurpose: PREVENTION masking: SINGLE maskingDescription: The outcome assessors, who will call patients or relatives 30 days after surgery, will be masked for the allocated group. whoMasked: OUTCOMES_ASSES... |
<|newrecord|> nctId: NCT06334055 id: CIP-1091 briefTitle: [Trial of device that is not approved or cleared by the U.S. FDA] overallStatus: WITHHELD date: 2024-03-27 date: 2024-03-27 name: [Redacted] hasResults: False |
<|newrecord|> nctId: NCT06334042 id: GO 23/488 briefTitle: Examination of the Effects of Chromium Levels on Glucose Metabolism, Lipid Metabolism, Morbidity and Mortality Rates in Patients Followed in Intensive Care Unit overallStatus: RECRUITING date: 2024-02-01 date: 2024-08-01 date: 2024-09-01 date: 2024-03-27 date: ... |
Participants will give a single blood sample (into trace element serum tube) on the day of admission to the intensive care unit, along with routine blood tests, and samples will be taken once a week during their stay in the intensive care unit. conditions: Chromium Deficiency conditions: Diabetes Mellitus conditions: H... |
<|newrecord|> nctId: NCT06334029 id: 12.2022 briefTitle: Observational Study of the Structural-functional Connectome in Patients With Epilepsy overallStatus: RECRUITING date: 2023-06-22 date: 2026-11-22 date: 2026-12-31 date: 2024-03-27 date: 2024-03-27 name: IRCCS Eugenio Medea class: OTHER briefSummary: Over the past... |
<|newrecord|> nctId: NCT06334016 id: I-3597023 id: NCI-2024-01556 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: I-3597023 type: OTHER domain: Roswell Park Cancer Institute id: R01DA057228 type: NIH link: https://reporter.nih.gov/quickSearch/R01DA057228 briefTitle: Evaluating the Delivery and Effect... |
<|newrecord|> nctId: NCT06334003 id: H-23071266 briefTitle: Cardiometabolic Function in Offspring, Mother and Placenta After Assisted Reproductive Technology acronym: COMPART overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-04-30 date: 2027-12-01 date: 2024-03-27 date: 2024-03-27 name: Rigshospitalet, Denm... |
<|newrecord|> nctId: NCT06333990 id: 20220796HU briefTitle: Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI) overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2028-03 date: 2028-03 date: 2024-03-27 date: 2024-03-27 name: Foundation for Advancing Veterans' Health Research class:... |
<|newrecord|> nctId: NCT06333977 id: LG-GQCL001 briefTitle: A Study of LC542019 in Healthy Subjects and Subjects With T2DM overallStatus: COMPLETED date: 2022-03-25 date: 2023-12-14 date: 2023-12-14 date: 2024-03-27 date: 2024-03-27 name: LG Chem class: INDUSTRY briefSummary: to assess the safety, tolerability, Pharmac... |
<|newrecord|> nctId: NCT06333964 id: AST-001P_P301_ASD briefTitle: Phase III Clinical Trial to Evaluate the Efficacy and Safey of AST-001 in ASD Children overallStatus: RECRUITING date: 2023-08-29 date: 2024-09-30 date: 2024-12-31 date: 2024-03-27 date: 2024-03-27 name: Astrogen, Inc. class: INDUSTRY briefSummary: 1. S... |
2. Background: ASD is a neurodevelopmental disorder characterized by deficits in social communication and social interaction as well as restricted, repetitive patterns of behavior, interests, or activities. There are no approved medicines to treat the core symptom of ASD. Although these drugs and other psychotropic med... |
3. Design: Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 clinical trial followed by an Open-Label Extension Treatment Period conditions: Autism Spectrum Disorder studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Main study(0\~1... |
Extension study(12\~24 weeks) Experimental: AST-001 Comparator: AST-001 primaryPurpose: TREATMENT masking: QUADRUPLE whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 160 type: ESTIMATED name: AST-001 name: Placebo of AST-001 measure: K-VABS-II (Korean-Vineland ... |
<|newrecord|> nctId: NCT06333951 id: 20230167 briefTitle: AMG 193 Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) overallStatus: RECRUITING date: 2024-06-03 date: 2026-10-08 date: 2029-10-07 date: 2024-03-27 date: 2024-04-25 name: Am... |
<|newrecord|> nctId: NCT06333938 id: 01968 briefTitle: Veterans Enhanced Recovery Using Integrative Treatments Around Surgery acronym: VERITAS overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2024-12 date: 2025-06 date: 2024-03-27 date: 2024-03-27 name: Durham VA Medical Center class: FED briefSummary: The study a... |
<|newrecord|> nctId: NCT06333925 id: Pro00114183 briefTitle: Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study acronym: MISO-STIM overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-10-31 date: 2026-10-31 date: 2024-03-27 date: 2024-03-27 name: Duke University class: OTHER name: Misopho... |
Sixty adult participants with moderate to severe misophonia will be recruited and taught an emotion regulation skill and randomly assigned to receive one of two types of repetitive transcranial magnetic stimulation (rTMS). The study includes 9-10 visits: the remote screening visit(s), the initial MRI, the four neurosti... |
The study team member who will conduct the behavioral session will be kept blind to the type of neurostimulation the participant will receive. Participants will also be kept blinded to what neurostimulation they receive and their perception of what they received will be assessed at follow-up. The intervention provider ... |
Participants will only be told about the type of neurostimulation at the end of the study to protect against different expectations whoMasked: PARTICIPANT whoMasked: CARE_PROVIDER whoMasked: OUTCOMES_ASSESSOR count: 60 type: ESTIMATED name: High Frequency Repetitive Transcranial Magnetic Stimulation (HF rTMS) name: Sha... |
<|newrecord|> nctId: NCT06333912 id: ridgesplittingguided briefTitle: Accuracy of Guided Ridge Splitting With Simultaneous Implant Placement overallStatus: COMPLETED date: 2023-08-02 date: 2024-01-29 date: 2024-02-27 date: 2024-03-27 date: 2024-03-27 name: Alexandria University class: OTHER briefSummary: Assessing whet... |
<|newrecord|> nctId: NCT06333899 id: CONNECT2111 briefTitle: Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2027-09-01 date: 2034-09-01 date: 2024-03-27 date: 2024-03-27 name: Nationwide Children's Hospital class: OTHER name: Pfizer brief... |
<|newrecord|> nctId: NCT06333886 id: ciusss-nordmtl_ESG briefTitle: Use of Point-of-care Neuro-sacral Electrophysiology Following Spinal Cord Injury overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-18 date: 2028-12-31 date: 2028-12-31 date: 2024-03-27 date: 2024-03-27 name: Centre Integre Universitaire de Sante et Se... |
<|newrecord|> nctId: NCT06333873 id: P22-09 briefTitle: Impact of Age-related Macular Degeneration on Daily Living Activitie acronym: AMDAY overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2029-06 date: 2029-06 date: 2024-03-27 date: 2024-03-27 name: Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts cl... |
<|newrecord|> nctId: NCT06333860 id: M24-541 briefTitle: A Study to Learn How Safe and Effective Risankizumab is When Compared to Deucravacitinib to Treat Participants With Moderate Plaque Psoriasis and Who Need to Try Systemic Treatment (Works Throughout the Whole Body) overallStatus: NOT_YET_RECRUITING date: 2024-05-... |
This study is designed to enroll 336 participants 18 years of age and older with have been diagnosed with moderate chronic plaque psoriasis for at least 6 months prior to Baseline (Day 1) and who have not previously been treated with a biologic treatment (natural substance that is made by using living cells in a labora... |
Participants will be administered subcutaneous (SC) treatment of risankizumab every 12 weeks for up to 44 weeks or provided deucravacitinib oral tablets to be taken once daily. |
There may be higher treatment burden for participants in this trial compared to their standard of care (due to study procedures). Participants will attend regular (weekly, monthly) visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking ... |
<|newrecord|> nctId: NCT06333847 id: K2023-059 briefTitle: Is Multimorbidity a Source of Non-response Bias in Patients With Spinal Pain? - A Pilot Study overallStatus: ENROLLING_BY_INVITATION date: 2023-06-01 date: 2024-04-20 date: 2024-04-20 date: 2024-03-27 date: 2024-03-27 name: Jacob Christiansen Gandløse class: OT... |
<|newrecord|> nctId: NCT06333834 id: Dosis Seriada de Alacramyn briefTitle: Assessment of the Efficacy of Scorpion Antivenom Therapy in a Dose-response Manner, in Patients With Scorpionism overallStatus: NOT_YET_RECRUITING date: 2024-03-30 date: 2024-08-01 date: 2024-08-30 date: 2024-03-27 date: 2024-03-27 name: Selene... |
<|newrecord|> nctId: NCT06333821 id: BPL-Nim-CC-3003 briefTitle: A Study of Nimotuzumab Plus Concurrent Chemoradiotherapy Sequential Maintenance Treatment for Cervical Carcinoma overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2030-04-01 date: 2030-04-01 date: 2024-03-27 date: 2024-03-27 name: Biotech Pharmaceu... |
The primary hypotheses are that nimotuzumab plus concurrent chemoradiotherapy sequential maintenance therapy is superior to placebo plus concurrent chemoradiotherapy with respect to progression-free survival. conditions: Cervical Cancer studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: ... |
<|newrecord|> nctId: NCT06333808 id: GS-US-621-6290 id: 2023-510022-33 type: OTHER domain: European Medicines Agency briefTitle: Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy acronym: ARTISTRY-2 overallStatus: RECRUITING date: 2024-03-25 ... |
The primary objective of this study is to learn how effective it is to switch to BIC/LEN FDC tablets versus continuing on B/F/TAF FDC tablets in virologically suppressed PWH. conditions: HIV-1-infection studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescript... |
<|newrecord|> nctId: NCT06333795 id: 1-10-72-131-23 briefTitle: Faecal Microbiota Transplantation Against Chronic Diarrhea in Patients With Systemic Sclerosis acronym: FaeMiCue overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-01-31 date: 2025-12-31 date: 2024-03-27 date: 2024-03-27 name: University of Aarh... |
<|newrecord|> nctId: NCT06333782 id: 2023-EU-GEN-01 id: 2023-A02012-43 type: OTHER domain: ANSM briefTitle: Evaluation of the Safety and Efficacy of Hyaluronic Acid Injection in Labia Majora Augmentation overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2025-07-01 date: 2025-07-01 date: 2024-03-27 date: 2024-04-... |
The primary objective is the evaluation of the safety of Genefill Contour®. The secondary objectives is effectivenes of the investigational device (improvement of patient´s symptoms, patient´s satisfaction, sexual function \& pain during injection). |
Participants will come to a total of 8 visits (including 2 phone calls) over a period of 12 months. Participants would be enrolled in Genefill Contour® or comparator group. |
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