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The primary objectives of the study are: |
1. To explore and describe any differences in the gut microbiota especially Shannon diversity index |
2. To conduct functional profiling by exploring and describing any differences in functional metabolites produced in the gut in people having had pancreatoduodenectomy greater than 6 months ago compared to healthy matched controls. |
Participants will be asked to complete the following: |
* Three-day food, bowel and medication diary (see Protocol appendix 5) |
* Gastrointestinal Symptom Rating Scale (see Protocol appendix 6) |
* Quality of life questionnaire (see Protocol appendix 7) |
* Stool sample test using Microba Insight TradeMark (a small swab is taken from soiled toilet paper, sealed in a room-temperature storage capsule and mailed to the testing laboratory) conditions: Pancreatic Cancer conditions: Microbiota conditions: Pancreatoduodenectomy studyType: OBSERVATIONAL observationalModel: CASE... |
<|newrecord|> nctId: NCT06319742 id: NSISTRCR_2201 briefTitle: Extracellular Vesicle Surface Markers In Acute Cerebrovascular Syndromes. acronym: ElViS-ACS overallStatus: RECRUITING date: 2022-11-18 date: 2025-12-31 date: 2026-01-31 date: 2024-03-20 date: 2024-04-18 name: Ospedale Civico, Lugano class: OTHER_GOV briefS... |
Transient Ischemic Attacks (TIAs) represent a classical example for which a biomarker would be of interest to confirm and distinguish a brain ischemic process from a stroke mimic. Diagnostic biomarkers of TIA have been investigated, but none of the potential candidates reached enough accuracy for TIA diagnosis. Our gro... |
<|newrecord|> nctId: NCT06319729 id: REC/22-23/0659 briefTitle: A Chinese Herbal Medicine for IBS-C acronym: CDD2105RCT1 overallStatus: NOT_YET_RECRUITING date: 2024-03-25 date: 2024-08-31 date: 2024-11-30 date: 2024-03-20 date: 2024-03-21 name: Hong Kong Baptist University class: OTHER briefSummary: This double-blind,... |
<|newrecord|> nctId: NCT06319716 id: 23-01274 briefTitle: Leveraging Videos and Community Health Workers to Address Social Determinants of Health in Immigrants acronym: LINK-IT overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2027-12-31 date: 2028-06-30 date: 2024-03-20 date: 2024-04-05 name: NYU Langone Health... |
<|newrecord|> nctId: NCT06319703 id: 22-00634 briefTitle: Implementing an Effective Diabetes Intervention Among Low-Income Immigrants acronym: IDEAL overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-10-31 date: 2028-03-31 date: 2024-03-20 date: 2024-03-20 name: NYU Langone Health class: OTHER name: Agency f... |
<|newrecord|> nctId: NCT06319690 id: REC/RCR&AHS/23/0362 briefTitle: Combined Effects of Lion's Breath Technique With Chest Percussion Therapy in Pneumonia Patients overallStatus: RECRUITING date: 2024-03-01 date: 2024-06-05 date: 2024-06-15 date: 2024-03-20 date: 2024-03-20 name: Riphah International University class:... |
<|newrecord|> nctId: NCT06319677 id: Ivljingjing briefTitle: PK/PD Study of Anti-Infective Drugs in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation Treatment acronym: ECMO overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-05-01 date: 2027-05-01 date: 2024-03-20 date: 2024-03-20 name: T... |
<|newrecord|> nctId: NCT06319664 id: sjnkzzj briefTitle: Clinical Outcomes and Decision-making Choice of Skull Base Approaches for Petroclival Meningiomas overallStatus: COMPLETED date: 2021-05-27 date: 2021-08-10 date: 2021-09-10 date: 2024-03-20 date: 2024-03-20 name: Xiangya Hospital of Central South University clas... |
<|newrecord|> nctId: NCT06319651 id: REC/RCR&AHS/23/0360 briefTitle: Effects of Lower Limb Resistance Band Exercises in Phase 1 Cardiac Rehabilitation overallStatus: RECRUITING date: 2024-03-01 date: 2024-06-05 date: 2024-06-15 date: 2024-03-20 date: 2024-03-27 name: Riphah International University class: OTHER briefSu... |
<|newrecord|> nctId: NCT06319638 id: SGB TBI briefTitle: Efficacy of Stellate Ganglion Block in Traumatic Brain Injury Patients overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2024-12 date: 2024-12 date: 2024-03-20 date: 2024-03-20 name: Copka Sonpashan class: OTHER_GOV briefSummary: The goal of this or clinical ... |
Can stellate ganglion block improve the dysphagia and activities of daily living in Traumatic Brain Injury Patients. |
Traumatic Brain Injury Patients will be divided into the the control group and observation group evenly. All the patients were provided with routine therapy, while the patients in the observation group were given stellate ganglion block. The swallowing function, and activities of daily living of the two groups of patie... |
<|newrecord|> nctId: NCT06319625 id: SGB PARKINSON briefTitle: Effectiveness of Stellate Ganglion Block in Patients Diagnosed With Parkinson's Disease overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-12 date: 2024-12 date: 2024-03-20 date: 2024-03-20 name: Copka Sonpashan class: OTHER_GOV briefSummary: The go... |
• Can stellate ganglion block improve the dysphagia and activities of daily living in patients with Parkinson's disease. |
Participants will be divided into the the control group and observation group evenly. All the patients were provided with routine therapy, while the patients in the observation group were given stellate ganglion block. The swallowing function, and activities of daily living of the two groups of patients before and afte... |
<|newrecord|> nctId: NCT06319612 id: SGB OSA DOUBLE BLIND briefTitle: Effectiveness of Stellate Ganglion Block for the Treatment of Obstructive Sleep Apnea overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-12 date: 2024-12 date: 2024-03-20 date: 2024-03-20 name: Copka Sonpashan class: OTHER_GOV briefSummary: T... |
• Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were randomly divided into two groups, all provided with routine therapy. Based on this, the experimental group was given stellate ganglion block. The video fluoroscopic swallowing study was done to test the swallowing function before and after the... |
<|newrecord|> nctId: NCT06319599 id: SGB GUDU briefTitle: Stellate Ganglion Block in Children With Autistic Disorder overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-12 date: 2024-12 date: 2024-03-20 date: 2024-03-20 name: Copka Sonpashan class: OTHER_GOV briefSummary: The goal of this clinical trial is to ex... |
Can stellate ganglion block improve the Autistic Disorder in children? Children with Autistic Disorder will be divided into the control group and experimental group evenly. All the patients were provided with routine therapy, while the patients in the experimental group were given stellate ganglion block. The Childhood... |
<|newrecord|> nctId: NCT06319586 id: Soh-Med-24-02-08MS briefTitle: The Radial Forearm Flap In Reconstruction Of Upper Limb Injuries overallStatus: COMPLETED date: 2024-02-07 date: 2024-02-07 date: 2024-02-07 date: 2024-03-20 date: 2024-03-20 name: Sohag University class: OTHER briefSummary: The radial forearm flap is ... |
<|newrecord|> nctId: NCT06319573 id: 2305-UNIVF-070-DC briefTitle: The Impact of Personalized Prognostic Counseling on IVF Patient's Experience and Treatment Utilization overallStatus: RECRUITING date: 2024-03-19 date: 2025-08-31 date: 2026-02-28 date: 2024-03-20 date: 2024-04-19 name: Ginefiv class: OTHER name: Univfy... |
<|newrecord|> nctId: NCT06319560 id: JEP-2023-866 briefTitle: Hydroxychloroquine in Type 2 Diabetes During Pregnancy overallStatus: RECRUITING date: 2024-01-02 date: 2026-01-01 date: 2027-01-01 date: 2024-03-20 date: 2024-04-19 name: National University of Malaysia class: OTHER briefSummary: The goal of this clinical t... |
The main questions it aims to answer are: |
* Does hydroxychloroquine improve the pregnancy outcomes in women with type 2 diabetes during pregnancy? |
* Does hydroxychloroquine improve the inflammatory markers in women with type 2 diabetes during pregnancy? Participants will be randomised into the intervention and control group. The control group will be on standard treatment where as the intervention group will receive hydroxychloroquine as an adjunct of standard tr... |
<|newrecord|> nctId: NCT06319547 id: Soh-Med-24-02-07MS briefTitle: Comparing Outcome of Thoracocentesis and Pigtail Catheter Drainage in Treatment of Patients With Hepatic Hydrothorax overallStatus: RECRUITING date: 2024-02-20 date: 2025-02 date: 2025-03 date: 2024-03-20 date: 2024-03-20 name: Sohag University class: ... |
<|newrecord|> nctId: NCT06319534 id: SGB-ZHENQIU briefTitle: Stellate Ganglion Block in Bulbar Palsy overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-12 date: 2024-12 date: 2024-03-20 date: 2024-03-20 name: Copka Sonpashan class: OTHER_GOV briefSummary: This is a randomized controlled study, including dysphag... |
<|newrecord|> nctId: NCT06319521 id: SGB-REFLUX briefTitle: Stellate Ganglion Block on Gastroesophageal Reflux Disease overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-12 date: 2024-12 date: 2024-03-20 date: 2024-03-20 name: Copka Sonpashan class: OTHER_GOV briefSummary: The goal of this clinical trial is to ... |
• Can stellate ganglion block improve gastroesophageal reflux symptoms better on the basis of rehabilitation training? Participants will be randomly allocated into the control group or the experimental group, all under rehabilitation treatment, the experimental group will be given Stellate Ganglion Block once a day add... |
<|newrecord|> nctId: NCT06319508 id: SGB-NT briefTitle: Stellate Ganglion Block in Cerebral Palsy overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-12 date: 2024-12 date: 2024-03-20 date: 2024-03-20 name: Copka Sonpashan class: OTHER_GOV briefSummary: The goal of this clinical trial is to test the efficacy of ... |
• Can stellate ganglion block improve the dysphagia of children with cerebral palsy? Participants were randomly divided into two groups, all provided with routine therapy. Based on this, the experimental group was given stellate ganglion block. The video fluoroscopic swallowing study was done to test the swallowing fun... |
<|newrecord|> nctId: NCT06319495 id: SGB-CSVD briefTitle: Stellate Ganglion Block in Patients With Cerebral Small Vessel Disease overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-12 date: 2024-12 date: 2024-03-20 date: 2024-03-20 name: Copka Sonpashan class: OTHER_GOV briefSummary: This is a prospective study ... |
<|newrecord|> nctId: NCT06319482 id: Adherence Study briefTitle: The Adherence of Proactive Sleep Apnea Therapy overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-08-01 date: 2025-08-01 date: 2024-03-20 date: 2024-03-20 name: NovaResp Technologies Inc class: INDUSTRY briefSummary: The goal of this clinical t... |
1. To compare the adherence of proactive therapy and conventional Automatic-PAP (APAP) therapy short-term (3 months) and long-term (12 months) for newly diagnosed OSA patients. |
2. To compare health outcomes (AHI, nightly pressure, and patient-reported outcomes) between proactive therapy and conventional APAP therapy. conditions: Obstructive Sleep Apnea studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: DOUBLE whoMasked: P... |
<|newrecord|> nctId: NCT06319469 id: FMBSUREC/06122022/Mohamed briefTitle: The Additive Value of Pyridostigmine to Silodosin in Acute Urinary Retention overallStatus: COMPLETED date: 2023-02-01 date: 2024-01-30 date: 2024-01-30 date: 2024-03-20 date: 2024-03-20 name: Beni-Suef University class: OTHER briefSummary: Acut... |
<|newrecord|> nctId: NCT06319456 id: APG2575CC301 briefTitle: A Global Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL. overallStatus: RECRUITING date: 2024-04 date: 2027-08 date: 2028-08 date: 2024-03-20 date: 2024-04-16 name: Ascentage Pharma Group Inc... |
<|newrecord|> nctId: NCT06319443 id: STUDY00019235 briefTitle: Daily Vinegar Ingestion and 24-Hour Blood Glucose Control overallStatus: RECRUITING date: 2024-03 date: 2024-06 date: 2025-04 date: 2024-03-20 date: 2024-03-20 name: Arizona State University class: OTHER briefSummary: When linking dietary interventions and ... |
Recognizing this gap, the current study aims to utilize continuous glucose monitoring to examine the impact of daily vinegar ingestion on glucose variability in adults identified as glucose intolerant. conditions: Glucose Intolerance studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: CROSSOV... |
<|newrecord|> nctId: NCT06319430 id: HS26236(H2023:343) briefTitle: Technology in Play for Children With Physical Disabilities: the Dice Model of Play overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-04-30 date: 2025-05-28 date: 2024-03-20 date: 2024-03-20 name: University of Manitoba class: OTHER name: Re... |
There are some models of play. But they are not complete. They do not look at play as a whole. Some models are just about playfulness, and some are about playing with others. Having a model that defines play helps researchers and clinicians think about play and the different parts of it. Then, when a child cannot play,... |
<|newrecord|> nctId: NCT06319417 id: HT-UCAM briefTitle: Hydroxytyrosol Caramel Treatment on Cardiovascular Risk Patients overallStatus: COMPLETED date: 2022-04-15 date: 2023-03-23 date: 2023-03-23 date: 2024-03-20 date: 2024-03-20 name: Universidad Católica San Antonio de Murcia class: OTHER briefSummary: The goal of ... |
* Evaluating the effect of HT caramels on CVR biomarkers. |
* Assessing the impact of HT caramels on cellular phenotype. |
Participants will take 4 caramels/day, each containing 15 mg of HT, consuming a daily intake of 60 mg for 28 days. One group will begin with HT caramel consumption for 28 days, while the other group will start with a placebo treatment. Following a 2-week washout period, the treatments will be switched between the group... |
2-weeks washout period. The treatment will be switched between groups for another 28 days: those who initially consumed HT will the switch to the placebo treatment, and vice versa. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: Nor participant and care provider knew the treatment given. whoMasked: PARTIC... |
<|newrecord|> nctId: NCT06319404 id: 2022YFC2505700 briefTitle: Immune Function of Colorectal Cancer Lymph Nodes overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2026-04-01 date: 2024-03-20 date: 2024-03-20 name: Shanxi Province Cancer Hospital class: OTHER name: The Second Affiliated Hospital ... |
<|newrecord|> nctId: NCT06319391 id: JSZ007 briefTitle: Analysis of the Effect of Donor CYP3A5 Gene Polymorphism on Early Tacrolimus Concentration and Postoperative Acute Renal Injury After Liver Transplantation overallStatus: ACTIVE_NOT_RECRUITING date: 2023-04-01 date: 2024-05-01 date: 2025-10-01 date: 2024-03-20 dat... |
<|newrecord|> nctId: NCT06319378 id: CAPSI no 2 date 231024 id: 2023-505532-35-00 type: OTHER domain: CTIS briefTitle: Cancer Related Major Depression Treated With a Single Dose of Psilocybin acronym: CAPSI overallStatus: RECRUITING date: 2024-04-17 date: 2025-12 date: 2025-12 date: 2024-03-20 date: 2024-04-22 name: Se... |
The primary objective of this study is to evaluate the efficacy of a single 25 mg oral dose of psilocybin for major depressive disorder (MDD) compared to an active placebo (psilocybin 1 mg) assessed as the difference between groups in changes in depressive symptoms, in the following Population: 20-80 (inclusive) years ... |
≥10), \>1 month after cancer diagnosis, with at least 12 months of life expectancy, willingness to abstain from other psychotherapeutic or antidepressant treatments during the study (wash out time 5 half-lives). conditions: MDD studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL ... |
<|newrecord|> nctId: NCT06319365 id: gurcansolmaz briefTitle: Yoga on Women's Blood Pressure, Sexual Life, And Marital Compliance overallStatus: RECRUITING date: 2023-03-01 date: 2024-03-22 date: 2024-03-22 date: 2024-03-20 date: 2024-03-25 name: University of Yalova class: OTHER briefSummary: Introduction This study w... |
Method. The study will be a pre-post test randomized controlled study in accordance with CONSORT rules. Personal Information Form, Bloood pressure measurement, Arizona Sexual Experience Scale and Marital Adjustment Test will be used for data collection. conditions: Hypertension conditions: Sexuality studyType: INTERVEN... |
<|newrecord|> nctId: NCT06319352 id: HUM00243293 briefTitle: Evaluation of Quality-of-Life Improvements Using UroShield Device overallStatus: NOT_YET_RECRUITING date: 2024-05-31 date: 2024-10 date: 2024-10 date: 2024-03-20 date: 2024-04-26 name: University of Michigan class: OTHER name: Nanovibronix briefSummary: The g... |
The main questions the investigators aim to answer focus on implementation and practicality: |
* Recruitment feasibility and time to recruit |
* How well do participants adhere to device protocol? |
* How often do device components (i.e., actuators and drivers) have to be replaced? |
* How much time is required for data collection and what sources or methods for data collection are used? |
Results of this pilot study will inform the investigators as to necessary protocol modifications and overall feasibility for the larger randomized clinical trial to follow. conditions: Quality of Life conditions: Catheter-Associated Urinary Tract Infection studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED int... |
<|newrecord|> nctId: NCT06319339 id: 0419-23-FB briefTitle: Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease overallStatus: NOT_YET_RECRUITING date: 2024-08 date: 2025-08 date: 2025-08 date: 2024-03-20 date: 2024-03-20 name: University of Nebraska ... |
<|newrecord|> nctId: NCT06319326 id: Postfeed Intestinal Perfusion briefTitle: Intestinal Perfusion After Feeding in Preterm and Term Infants overallStatus: NOT_YET_RECRUITING date: 2024-04-02 date: 2024-06-30 date: 2024-08-31 date: 2024-03-20 date: 2024-03-20 name: The Hospital for Sick Children class: OTHER name: Xia... |
<|newrecord|> nctId: NCT06319313 id: JMT101-013 briefTitle: Efficacy and Safety of JMT101 Combined Wth Docetaxel / HB1801 in Patients With Squamous Cell Non-Small Cell Lung Cancer overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-07-01 date: 2027-12-01 date: 2024-03-20 date: 2024-03-20 name: Shanghai JMT-Bi... |
<|newrecord|> nctId: NCT06319300 id: 20240115023245436 briefTitle: Artificial Intelligence-assisted Insulin System in Type 2 Diabetes in General Wards overallStatus: RECRUITING date: 2024-04-19 date: 2026-03-20 date: 2026-05-20 date: 2024-03-20 date: 2024-04-22 name: Shanghai Zhongshan Hospital class: OTHER name: Shang... |
<|newrecord|> nctId: NCT06319287 id: PRO-00125 briefTitle: Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU) overallStatus: RECRUITING date: 2024-02-27 date: 2025-04-05 date: 2025-07-12 date: 2024-03-20 date: 2024-04-16 name: Rion... |
<|newrecord|> nctId: NCT06319274 id: COMBAT-ARF briefTitle: Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Failure acronym: COMBAT-ARF overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-12-30 date: 2026-12-30 date: 2024-03-20 date: 2024-03-20 name:... |
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