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<|newrecord|> nctId: NCT06319261 id: 858623 briefTitle: Efficacy of Guided Biofilm Therapy (GBT) for Treatment of Deep Periodontal Pockets. overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-10 date: 2024-12 date: 2024-03-20 date: 2024-03-20 name: University of Baghdad class: OTHER briefSummary: the aim of the ... |
the objectives are |
1- To compare the change in the clinical periodontal parameters and microbiological parameters by using real time PCR for P. gingivalis, Aggregatibacter actinomycetemcomitans and Filifactor alocis among sites treated by GBT and conventional hand instrumentation after a period of 3 months and to assess the level of the ... |
the hypothesis is whether there are no differences in in the clinical and microbiological parameters among sites treated by GBT and conventional hand instrumentation after a period of 3 months or there are differences in in the clinical and microbiological parameters among sites treated by GBT and conventional hand ins... |
The participants will be selected on a consecutive basis from patients referred to the Department of Periodontics, College of Dentistry, University of Baghdad. |
For each patient, each site will be randomly assigned to either treatment protocol: |
1. Sites treated with GBT. |
2. Sites treated with conventional manual instrumentation only. conditions: Periodontitis studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR count: 25 type: ESTIMATED name: guided biofilm therapy name: root surfa... |
<|newrecord|> nctId: NCT06319248 id: 24-000121 briefTitle: Use of Midodrine in Septic Shock Patients overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2029-05-30 date: 2029-07-30 date: 2024-03-20 date: 2024-04-16 name: Mayo Clinic class: OTHER briefSummary: This study is being done to determine if early administ... |
<|newrecord|> nctId: NCT06319235 id: DUO2022_01 id: 2022-002412-23 type: EUDRACT_NUMBER briefTitle: Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG® overallStatus: RECRUITING date: 2023-10-27 date: 2025-12-31 date: 2025-12-31 date: 2024-03-19 date: 2024-03-19 name: MB PHARMA s.r.o. class: INDUSTRY brief... |
The primary objective of the study is to demonstrate the safety of DUOFAG® and the clinical and microbiological change within 10 weeks after the start of treatment or until healing. conditions: Surgical Site Infection conditions: Staphylococcus Aureus Infection conditions: Pseudomonas Aeruginosa Infection conditions: B... |
<|newrecord|> nctId: NCT06319222 id: 23-007870 briefTitle: Implementation of a Digital Clinic for Alcohol-associated Liver Disease and Alcohol Use Disorder (DALC) acronym: DALC overallStatus: RECRUITING date: 2024-03-12 date: 2024-09 date: 2025-04 date: 2024-03-19 date: 2024-04-01 name: Mayo Clinic class: OTHER name: R... |
The primary aim of this study is to improve clinical outcomes in patients with ALD through the implementation of a novel digital health platform for personalized multi-disciplinary treatment of patients with ALD and AUD. Secondary aims include improvement in provider and patient-reported outcomes including satisfaction... |
<|newrecord|> nctId: NCT06319209 id: 2024KY023 briefTitle: Timing of Surgery and the Evolution of Postoperative Outcomes in Breast Cancer Patients Undergoing Surgical Intervention Following Recovery From SARS-CoV-2 Infection overallStatus: ACTIVE_NOT_RECRUITING date: 2023-01-01 date: 2023-03-31 date: 2024-03-31 date: 2... |
<|newrecord|> nctId: NCT06319196 id: Clear Me briefTitle: Clear Me: Interception Trial to Detect and Clear Molecular Residual Disease in Patients With High-risk Melanoma acronym: ClearMe overallStatus: RECRUITING date: 2024-05-01 date: 2027-02-15 date: 2030-02-15 date: 2024-03-19 date: 2024-04-22 name: University Healt... |
<|newrecord|> nctId: NCT06319183 id: 2023tjdxsy045 briefTitle: The Regulatory Function of Inhaled Asthma Medication Salbutamol on Thermogenesis overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-06 date: 2025-03 date: 2024-03-19 date: 2024-03-19 name: Tongji University class: OTHER briefSummary: In recent years... |
Mammalian adipose tissue is primarily divided into energy-storing white fat and energy-consuming brown fat. Physical activity, exposure to cold, and other factors induce the transformation of white fat into energy-consuming brown fat, a process known as adipose tissue browning. The occurrence of adipose tissue browning... |
The main component of asthma medication is the β2 adrenergic receptor agonist, which can act on GPCR receptors on the surface of the tracheal smooth muscle through inhalation, causing bronchial dilation and thereby alleviating asthma symptoms. Preliminary experimental results have shown that pulmonary epithelial cells ... |
<|newrecord|> nctId: NCT06319170 id: TV44749-NPC-10205 briefTitle: Open-label Trial Characterizing the PK of 3 SC Olanzapine Extended-release Formulations in Participants With Schizophrenia/Schizoaffective Disorder overallStatus: RECRUITING date: 2024-03-28 date: 2024-12-11 date: 2024-12-11 date: 2024-03-19 date: 2024-... |
A secondary objective is to evaluate the safety and tolerability of 3 formulations of olanzapine. |
Another secondary objective is to characterize the pharmacokinetics of ZYPREXA. |
The planned duration of the study for each participant is 19 weeks. conditions: Schizophrenia, Schizoaffective Disorder studyType: INTERVENTIONAL phases: PHASE1 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 95 type: ESTIMATED name: Olanzapine Extended Release name: Ol... |
<|newrecord|> nctId: NCT06319157 id: SYSKY-2023-1263-02 briefTitle: Minimal Access Versus Conventional Latissimus Dorsi Flap Harvest for Breast Reconstruction overallStatus: RECRUITING date: 2024-03 date: 2028-11 date: 2028-11 date: 2024-03-19 date: 2024-03-19 name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen Universi... |
<|newrecord|> nctId: NCT06319144 id: KYLL20240306-1 briefTitle: Effect of Intravenous 5% Dextrose Infusion During Recovery From Anesthesia on the Quality of Early Postoperative Recovery in Patients Undergoing Painless Gastrointestinal Endoscopy overallStatus: RECRUITING date: 2024-03-14 date: 2024-03-14 date: 2024-05-0... |
<|newrecord|> nctId: NCT06319131 id: Tipharosis briefTitle: Nadroparin Versus TIPS in Cirrhotic Patients With Refractory Asymptomatic PVT overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-30 date: 2026-05-30 date: 2024-03-19 date: 2024-03-21 name: Shanghai Zhongshan Hospital class: OTHER name: Shanghai 6... |
<|newrecord|> nctId: NCT06319118 id: JD-LK2023091-I01 briefTitle: A Clinical Study of Dihydroergotine Mesylate Extended-release Tablets for the Treatment of Drooling in Parkinson's Disease. overallStatus: ACTIVE_NOT_RECRUITING date: 2023-10-01 date: 2024-06-30 date: 2024-12-30 date: 2024-03-19 date: 2024-03-19 name: Se... |
Expected results: The improvement effect of dihydroergotine mesylate sustained-release tablets on PD salivation was significantly different from that of the placebo control group. The dihydroergotine mesylate sustained-release tablet group had a significant effect on the cognitive function of PD patients. conditions: S... |
<|newrecord|> nctId: NCT06319105 id: 775736 briefTitle: PathToScale: An Implementation Evaluation overallStatus: RECRUITING date: 2024-03-26 date: 2026-04-01 date: 2026-04-01 date: 2024-03-19 date: 2024-03-29 name: Georgetown University class: OTHER name: AIDS Vaccine Advocacy Coalition name: Centers for Disease Contro... |
<|newrecord|> nctId: NCT06319092 id: 2023/175 briefTitle: Immersive Virtual Reality Version of the 6 Minute Pegboard and Ring Test overallStatus: COMPLETED date: 2023-06-01 date: 2023-10-01 date: 2023-12-01 date: 2024-03-19 date: 2024-03-19 name: Gaziantep Islam Science and Technology University class: OTHER briefSumma... |
<|newrecord|> nctId: NCT06319079 id: UCTH 2024 briefTitle: Effect of Consumption of a Milk Product Designed for Lactating Women on Human Milk Composition overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-03 date: 2027-07 date: 2024-03-19 date: 2024-03-19 name: Instituto de Desarrollo e Investigaciones Pediátri... |
The main objective is to evaluate the effect of the consumption of a milk product (SMM) designed for lactating women on the composition of human milk and the nutritional status of iron and DHA in infant red blood cells in a vulnerable population through a randomized, triple-blind, controlled clinical trial. |
Specific objectives To compare the concentrations of DHA, Vitamins A, E, and D, Iron, Iodine, Zinc and Calcium in human milk before and after dietary supplementation with SMM. |
To compare the concentrations of DHA, Vitamins A, E, D and Zinc in blood and the nutritional status of maternal iron before and after dietary supplementation with SMM. |
To analyze the relationship between micronutrients measured in maternal blood and human milk after dietary supplementation with SMM. |
To compare the concentrations of micronutrients measured in blood and human milk in women who received SMM and those who received commercial milk (CM) at the end of supplementation. |
To compare the iron nutritional status and DHA content in red blood cells of infants of mothers who consumed SMM or LC. |
To evaluate the relationship between the concentration of micronutrients in human milk and infant growth during the first six months of life. conditions: Lactating Mothers conditions: Infants studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: QUAD... |
<|newrecord|> nctId: NCT06319066 id: RGNS65-152 briefTitle: Customized Foot Orthoses With Orthotic Wedges for Plantar Heel Pain overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-11-30 date: 2024-12-31 date: 2024-03-19 date: 2024-03-19 name: Mahidol University class: OTHER briefSummary: The present study wil... |
<|newrecord|> nctId: NCT06319053 id: NL85402.078.23 briefTitle: The Turbine-based Insufflator Safety and Feasibility Study acronym: TBI overallStatus: RECRUITING date: 2024-03-04 date: 2024-09 date: 2024-10 date: 2024-03-19 date: 2024-04-10 name: Erasmus Medical Center class: OTHER name: Politecnico di Milano Universit... |
<|newrecord|> nctId: NCT06319040 id: MEDİPOL MEGA 1 briefTitle: The Effect Of Addıtıonal Surgery On Muscle Strength, Proprıoceptıon And Balance In Anterıor Crucıate Lıgament Surgery overallStatus: COMPLETED date: 2018-12-06 date: 2019-03-07 date: 2019-06-07 date: 2024-03-19 date: 2024-03-19 name: Medipol University cla... |
<|newrecord|> nctId: NCT06319027 id: EAF223 id: NCI-2023-08557 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: EAF223 type: OTHER domain: ECOG-ACRIN Cancer Research Group id: EAF223 type: OTHER domain: CTEP id: U10CA180820 type: NIH link: https://reporter.nih.gov/quickSearch/U10CA180820 briefTitle: I... |
<|newrecord|> nctId: NCT06319014 id: 23-001568 briefTitle: Physical Activity to Mitigate PreEclampsia Risk acronym: PAMPER overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2026-04-01 date: 2026-10-01 date: 2024-03-19 date: 2024-03-19 name: East Carolina University class: OTHER briefSummary: The purpose of this ... |
Aim 1. Determine the influence of different exercise modes during pregnancy at risk of preeclampsia on maternal cardiometabolic health. |
Aim 2. Determine the most effective exercise mode in pregnancy at risk of preeclampsia on improving birth and infant health outcomes. conditions: Pre-Eclampsia studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Pregnant women will be randomized to one o... |
<|newrecord|> nctId: NCT06319001 id: 2688791 briefTitle: Cardiovascular Reactivity to Physical Stress acronym: REACT overallStatus: RECRUITING date: 2024-02-19 date: 2027-01-01 date: 2027-01-01 date: 2024-03-19 date: 2024-03-19 name: Western Norway University of Applied Sciences class: OTHER briefSummary: It is well-ac... |
<|newrecord|> nctId: NCT06318988 id: S67030 briefTitle: Outcomes of Different Treatment Options in Chronic Venous Disease acronym: VOS overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-11-01 date: 2027-05-01 date: 2024-03-19 date: 2024-03-19 name: Universitaire Ziekenhuizen KU Leuven class: OTHER briefSumma... |
<|newrecord|> nctId: NCT06318975 id: RAPTOR id: R01AA029074 type: NIH link: https://reporter.nih.gov/quickSearch/R01AA029074 briefTitle: Text-Based Messaging Strategies for Preventing Subsequent Problematic Alcohol Use overallStatus: RECRUITING date: 2023-12-01 date: 2027-12-31 date: 2028-12-31 date: 2024-03-19 date: 2... |
Brief Alcohol Interventions (BAIs) for alcohol misuse are effective in young adults who report binge drinking. Many BAI studies targeted young adults who drink hazardously; these individuals are typically not interested in abstaining but may try decreasing the amount or change the manner in which they drink in order to... |
One challenge to conducting alcohol research in the military is the lack of privileged communication. As a result, it is difficult to obtain valid self-reports due to a tendency to deny or minimize use. The investigators recently developed and validated a method for collecting anonymous data over time. This will be the... |
<|newrecord|> nctId: NCT06318962 id: UMemphis id: SPC-1000007404 GR127268 type: OTHER domain: Department of Defense briefTitle: Examining the Efficacy of a Digital Therapeutic to Prevent Suicidal Behaviors overallStatus: RECRUITING date: 2024-02-07 date: 2027-08-01 date: 2027-08-01 date: 2024-03-19 date: 2024-03-19 nam... |
<|newrecord|> nctId: NCT06318949 id: 87RI22_0007 (MALAHBAR) briefTitle: Albumin Modifications as Early Biomarkers of Chronic Liver Diseases acronym: MALAHBAR overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2029-06-01 date: 2029-12-01 date: 2024-03-19 date: 2024-03-19 name: University Hospital, Limoges class: O... |
Our preliminary results from animal models and a proof-of-concept studies with patients support this hypotheses. Our previous studies demonstrated also significant differences in albumin isoform profiles in response to different types of hepatic injury and high sensitivity and specificity in the SEB test among cirrhoti... |
The primary objective of the MALAHBAR project is to evaluate the capacity of albumin PTM to predict liver disease progression over three years in chronic liver disease patients. Secondary objectives include assessing the predictive ability of different albumin isoforms and the SEB test for liver disease progression, ev... |
<|newrecord|> nctId: NCT06318936 id: 22-677 briefTitle: Respiratory Syncytial Virus (RSV) Burden in Older Adults in Primary Care in The Netherlands acronym: RAPID overallStatus: RECRUITING date: 2022-11-01 date: 2024-05-01 date: 2024-05-01 date: 2024-03-19 date: 2024-03-19 name: UMC Utrecht class: OTHER name: Janssen-C... |
With this prospective, observational study, we aim to define the disease burden of RSV infection in older adults in the primary care setting. conditions: RSV Infection studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED measure: Burden of medically attended RSV in... |
<|newrecord|> nctId: NCT06318923 id: RC-P00117 briefTitle: Social and Moral Cognition in Multiple Sclerosis acronym: COSMOS overallStatus: RECRUITING date: 2023-12-19 date: 2025-04-30 date: 2025-10-30 date: 2024-03-19 date: 2024-03-20 name: Lille Catholic University class: OTHER briefSummary: Multiple Sclerosis (MS) is... |
The objective of this project is to analyze the process of decision-making carried out by patients during moral dilemma situations in comparison with control individuals and verify whether the presence of a positivity bias could explain the more deontological choices made by some patients. Indeed, some work has shown t... |
<|newrecord|> nctId: NCT06318910 id: MU-SRF-RS-27 C/66 briefTitle: Customized Foot Orthoses on Muscle Activity During Standing and Gait in Plantar Heel Pain overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-11-30 date: 2024-12-31 date: 2024-03-19 date: 2024-03-19 name: Mahidol University class: OTHER briefS... |
<|newrecord|> nctId: NCT06318897 id: 2023-0645 id: NCI-2024-02384 type: OTHER domain: NCI-CTRP Clinical Registry briefTitle: Open-label, Single Center, Single-arm, Phase 2 Study of Neoadjuvant Pembrolizumab in Combination With Carboplatin and Paclitaxel in Patients With Stage 1 cT1b-T1cN0M0 Triple Negative Breast Cance... |
<|newrecord|> nctId: NCT06318884 id: SCTB35-X101 briefTitle: A First-in-human Study of SCTB35 in Patients With Relapse/Refractory B-cell Non-Hodgkin Lymphoma overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-10 date: 2027-12 date: 2024-03-19 date: 2024-03-22 name: Sinocelltech Ltd. class: INDUSTRY briefSummary... |
<|newrecord|> nctId: NCT06318871 id: 23-688 briefTitle: A Phase 0 Pilot Study of Memory-like Natural Killer (NK) Cell Immune Therapy in Combination With N-803 in Patients With Renal Cell Carcinoma or Urothelial Carcinoma overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-02-28 date: 2030-02-28 date: 2024-03-19 ... |
Names of the study therapies involved in this study are/is: |
* CIML NK cell therapy (a NK cell therapy) |
* N-803 (a type of recombinant human IL-15 superagonist) conditions: Renal Carcinoma conditions: Renal Cell Carcinoma conditions: Urothelial Carcinoma studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: NON_RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 5 type: ESTIMATE... |
<|newrecord|> nctId: NCT06318858 id: MU-CIRB 2022/313.1411 briefTitle: Daily and Weekly Iron Supplementation in Infants overallStatus: RECRUITING date: 2023-03-15 date: 2024-08-14 date: 2024-10-14 date: 2024-03-19 date: 2024-04-05 name: Mahidol University class: OTHER name: Suranaree University of Technology briefSumma... |
<|newrecord|> nctId: NCT06318845 id: 2302CS-1 briefTitle: Phase 1 Study to Evaluate the Safety and Pharmacokinetic Drug Interaction of DHP2302R1 and DHP2302R2 overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-04 date: 2024-07-19 date: 2024-08-02 date: 2024-03-19 date: 2024-03-19 name: Daehwa Pharmaceutical Co., Ltd. c... |
<|newrecord|> nctId: NCT06318832 id: 124609 briefTitle: Optimizing a Wellbeing Program for Care-partners of Those With SCI overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2024-06 date: 2025-06 date: 2024-03-19 date: 2024-03-19 name: Lawson Health Research Institute class: OTHER briefSummary: Spinal cord injuries ... |
In a previous feasibility study, the team demonstrated the preliminary effectiveness of a tailored ICBT Wellbeing program for fcSCI. However, our understanding of which components of the program can result in optimal management is limited. The main purpose of this study is to evaluate the effectiveness of different com... |
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