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Geriatric individuals may be at risk of falling in different situations, often inside and outside the home. Falls generally occur more frequently in indoor areas such as bathrooms, kitchens and bedrooms. In these areas, falls caused by potentially dangerous factors such as slippery floors, carpet edges, and high thresh... |
<|newrecord|> nctId: NCT06307756 id: SayıNo:521 briefTitle: The Effect of Music on Maternal Stress and Milk Amount overallStatus: RECRUITING date: 2023-11-15 date: 2024-04-15 date: 2024-06-15 date: 2024-03-13 date: 2024-03-13 name: Adiyaman University class: OTHER briefSummary: Premature babies who have to deal with li... |
<|newrecord|> nctId: NCT06307743 id: RAPID-SAVE briefTitle: Rapid Local Ischemic Postconditioning in Acute Ischemic Stroke acronym: RAPID-SAVE overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2025-06-15 date: 2025-09-15 date: 2024-03-13 date: 2024-03-13 name: Shanghai Jiao Tong University Affiliated Sixth Peopl... |
<|newrecord|> nctId: NCT06307730 id: CHSD_0033_GERIATRIE briefTitle: Application of the Recommendations of the SPLIF (French Society of Infectious Pathology) in a Geriatric Population on the Duration of Treatment for Bacterial Pneumonia overallStatus: COMPLETED date: 2023-01-02 date: 2023-04-30 date: 2023-04-30 date: 2... |
Two theses have shown that these recommendations were poorly applied in geriatric services. Indeed, the duration of treatment exceeded 7 days, and less than 30% of antibiotic antibiotic treatments were re-evaluated at 72 hours. |
In 2021, the SPLIF ( published new recommendations reducing this duration to 5 days in the event of clinical improvement observed on the 3rd day of treatment. These new recommendations are based on studies, in which the average age of participants was 65 years. However, the average age of patients in geriatric short-st... |
In addition, the geriatric population is characterized by immunosenescence, pulmonary vulnerability and undernutrition, raising questions about the validity of these recommendations in the geriatric population. |
The investigators offer a monocentric, retrospective, observational study of the geriatric hospital Casanova to assess the application of SPLIF recommendations in the geriatric population. conditions: Pneumonia, Bacterial conditions: Pneumopathy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETRO... |
<|newrecord|> nctId: NCT06307717 id: PLAGH-DA-002 briefTitle: Effects of Volatile Anaesthetics on Incidence of Postoperative Depression and Anxiety in Elderly Patients overallStatus: COMPLETED date: 2020-04-01 date: 2021-10-31 date: 2022-04-30 date: 2024-03-13 date: 2024-04-10 name: Chinese PLA General Hospital class: ... |
<|newrecord|> nctId: NCT06307704 id: LUSPEEPORRPC briefTitle: Lung US for PEEP Optimization in Robotic Radical Prostatectomy or Cystectomy Patients overallStatus: RECRUITING date: 2024-03 date: 2024-09 date: 2024-09 date: 2024-03-13 date: 2024-03-15 name: Nazmy Edward Seif class: OTHER briefSummary: There is an increas... |
Preventing lung atelectasis without inducing overdistention of the lung is challenging. Many studies tried to optimize PEEP titration by using methods such as dead space fraction guided and static pulmonary compliance directed techniques, or by using electrical impedance tomography. However, the use of these methods is... |
Bedside Lung ultrasound is fast, easy and economic technique that is gaining interest in the operating room. Ultrasound-guided PEEP titration has been used in bariatric surgeries (different position and usually shorter procedure time) and proved effective in improving oxygenation, compliance and reducing the incidence ... |
The aim of this study is to evaluate the effectiveness of intraoperative individualized lung ultrasound-guided stepwise PEEP optimization in patients undergoing RARPC on oxygenation, intraoperative and early postoperative pulmonary complications. conditions: Prostate Cancer conditions: Urinary Bladder Cancer conditions... |
<|newrecord|> nctId: NCT06307691 id: 11423 briefTitle: Clinical and Radiographic Evaluation of Immediate Implant Placement Using Osseodensification Versus Traditional Drilling Protocol overallStatus: RECRUITING date: 2024-03-06 date: 2025-12-20 date: 2026-12-20 date: 2024-03-13 date: 2024-03-19 name: Cairo University c... |
Traditional oversized drilling is the regular manufacturer recommended technique of drilling. It functions by cutting the bone during osteotomy preparation by sharp fluted drills. The undersizing of the preparation allows the implant to partially compact the bone during insertion. |
The objective of the current study is to compare between osseodensification drilling protocol versus traditional undersized drilling protocol in immediate implant placement in anterior maxillary region in terms of implant stability. conditions: Implant Complication studyType: INTERVENTIONAL phases: NA allocation: RANDO... |
Masking/blinding: |
* Participants will be blinded |
* Blinding of the operator will be blinded |
* The outcome assessor will be blinded |
* The biostatistician will be blinded whoMasked: PARTICIPANT whoMasked: INVESTIGATOR whoMasked: OUTCOMES_ASSESSOR count: 26 type: ESTIMATED name: Conventional drilling name: Osseodensification drilling measure: Implant stability quotient (ISQ) measure: Crestal bone level sex: ALL minimumAge: 20 Years maximumAge: 60 Yea... |
<|newrecord|> nctId: NCT06307678 id: AtaturkU-DHF-MS-01 briefTitle: Effect of Calcium Silicate Based Root Canal Medicament on Inflammatory Mediators overallStatus: COMPLETED date: 2023-07-07 date: 2023-12-10 date: 2023-12-10 date: 2024-03-13 date: 2024-03-13 name: Ataturk University class: OTHER briefSummary: Calcium h... |
The aim of this study was to investigate the effects of calcium silicate-based root canal medicament on the release of RANKL/OPG, TNF-α, PGE-2 and TGF-β1 in root canal treated teeth with periapical lesions. conditions: Periapical; Infection studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: ... |
<|newrecord|> nctId: NCT06307665 id: D6934C00001 briefTitle: Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma acronym: ACADIA overallStatus: NOT_YET_RECRUITING date: 2024-05-08 date: 2027-10-13 date: 2027-10-13 date: 2024-03-13 da... |
<|newrecord|> nctId: NCT06307652 id: D6402C00012 briefTitle: Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function acronym: BalanceD-HF overallStatus: NOT_YET_RECRUITING date: 2024-04-12 date: 2027-06-11 date: 2027-06-11 date: 2024-03-13 date: 2024-03-13 ... |
<|newrecord|> nctId: NCT06307639 id: MYMSwifee briefTitle: Seminal Levels of PGK2 and ACRV1 as Predictors of Micro-TESE Results in NOA overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-10-01 date: 2026-04-01 date: 2024-03-13 date: 2024-03-13 name: Assiut University class: OTHER briefSummary: * Measurement o... |
* Correlate seminal levels of PGK2 and ACRV1 with sperm retrieval results and histopathology analysis of testicular biopsy samples. conditions: Male Infertility Due to Azoospermia studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: PROSPECTIVE count: 64 type: ESTIMATED name: Measurement of PGK2 a... |
<|newrecord|> nctId: NCT06307626 id: ARGX-113-2309 id: 2023-509198-22-00 type: CTIS briefTitle: A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease. overallStatus: RECRUITING date: 2024-03-28 date: 2026-02 date: 2027-10 date: 2024-03-13 date: 2024-04-04 name: argenx class: INDU... |
After an up to 28-day screening period, eligible participants will be randomized in a 2:1 ratio to receive efgartigimod PH20 SC or placebo PH20 SC, respectively. Study drug will be administered subcutaneously during the 24-week double-blinded treatment period (DBTP). At the end of the DBTP (week 24), proptosis responde... |
<|newrecord|> nctId: NCT06307613 id: ARGX-113-2301 id: 2023-509197-35-00 type: CTIS briefTitle: A Study of Efgartigimod PH20 SC Given by Prefilled Syringe in Adults With Thyroid Eye Disease overallStatus: RECRUITING date: 2024-03-27 date: 2026-02 date: 2027-10 date: 2024-03-13 date: 2024-04-04 name: argenx class: INDUS... |
After an up to 28-day screening period, eligible participants will be randomized in a 2:1 ratio to receive efgartigimod PH20 SC or placebo PH20 SC, respectively. Study drug will be administered subcutaneously during the 24-week double-blinded treatment period (DBTP). At the end of the DBTP (week 24), proptosis responde... |
<|newrecord|> nctId: NCT06307600 id: BHCT-RD06-03 briefTitle: The Safety and Efficacy of RD06-03 CART Cell Injection in Patients With R/R Acute B-lymphoblastic Leukemia overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2025-03-15 date: 2027-04-01 date: 2024-03-13 date: 2024-03-13 name: Anhui Provincial Hospital ... |
<|newrecord|> nctId: NCT06307587 id: 2023/2355 briefTitle: Vastus Intermedius Dry Needling for Knee Stiffness Resulted From Surgically Managed Femoral Fractures With Open Reduction & Internal Fixation. overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2027-03-01 date: 2027-03-12 date: 2024-03-13 date: 2024-03-13... |
There are various surgical procedures which could be used to manage knee stiffness. However, there is no consensus regarding the ideal approach and strategy with many postoperative complications including deep sepsis, quadricep tendon rupture, skin dehiscence and infection, delayed wound healing, patella fracture, late... |
<|newrecord|> nctId: NCT06307574 id: STUDY00002804 briefTitle: bpMedManage: Digital Technology to Support Adherence to Hypertension Medications overallStatus: RECRUITING date: 2024-02-29 date: 2025-05 date: 2025-12 date: 2024-03-13 date: 2024-04-01 name: University of Arizona class: OTHER name: University of Illinois a... |
<|newrecord|> nctId: NCT06307561 id: GGurzoglu briefTitle: The Effect of Dystonia Severity on Participation in Daily Living Activities and Caregivers in Children of Cerebral Palsy With Secondary Dystonia overallStatus: COMPLETED date: 2021-01-01 date: 2024-01-01 date: 2024-01-01 date: 2024-03-13 date: 2024-03-13 name: ... |
<|newrecord|> nctId: NCT06307548 id: I-3670923 id: NCI-2024-01256 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: I-3670923 type: OTHER domain: Roswell Park Cancer Institute id: UL1TR001412 type: NIH link: https://reporter.nih.gov/quickSearch/UL1TR001412 briefTitle: Fluorescence Image Guided Surgery ... |
<|newrecord|> nctId: NCT06307535 id: 23-376 briefTitle: A Study of Meaning-Centered Psychotherapy for Caregivers to People With Cancer overallStatus: RECRUITING date: 2024-02-29 date: 2029-03-01 date: 2029-03-01 date: 2024-03-13 date: 2024-04-11 name: Memorial Sloan Kettering Cancer Center class: OTHER briefSummary: Pa... |
After participants complete the MCP-C or SP-C sessions and all 4 sets of questionnaires, their participation in this study will end. If participants decide not to complete all 7 sessions, they may still choose to complete the questionnaires. |
Participants may remain in the study and continue to receive all 7 sessions of MCP-C or SP-C even if their loved one passes away. conditions: Caregiver Burden conditions: Caregiver Burnout conditions: Caregiver Stress Syndrome studyType: INTERVENTIONAL phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL p... |
<|newrecord|> nctId: NCT06307522 id: MRG24ALC briefTitle: MRG-001 in Patients With Alcoholic Hepatitis overallStatus: NOT_YET_RECRUITING date: 2024-09-01 date: 2026-09-01 date: 2026-12-01 date: 2024-03-13 date: 2024-03-13 name: MedRegen LLC class: INDUSTRY briefSummary: The goal of this study is to test MRG-001 (an exp... |
<|newrecord|> nctId: NCT06307509 id: GN23AN097 briefTitle: Adiposity and Immunometabolism in Sepsis acronym: AIMS overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-04-30 date: 2025-07-31 date: 2024-03-13 date: 2024-03-13 name: NHS Greater Glasgow and Clyde class: OTHER name: University of Glasgow briefSummary:... |
First, the study will investigate differences in adipose tissue function (inflammation and mitochondrial function) related to obesity. Second, the investigators will examine whether lean critically ill patients with sepsis have enhanced adipose tissue inflammation and mitochondrial dysfunction compared to lean controls... |
Patients will be either undergoing emergency abdominal surgery, or will have been admitted to a critical care unit with a diagnosis of sepsis. |
The investigators will collect blood and adipose tissue biopsies from the patients, and these will be analysed for markers of inflammation and of mitochondrial function. |
The aim is to better understand the relationship between obesity, inflammation, mitochondrial dysfunction and sepsis. The investigators hope that this may improve the understanding of the pathophysiology of sepsis and allow more targeted interventions for patients based on differences in their baseline metabolic state.... |
<|newrecord|> nctId: NCT06307496 id: Pro00133913 briefTitle: VIDeOS for Smoking Cessation overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-04 date: 2025-07 date: 2024-03-12 date: 2024-03-12 name: Medical University of South Carolina class: OTHER name: Alliance NCORP Research Base Cancer Control Program briefS... |
<|newrecord|> nctId: NCT06307483 id: 20240108 briefTitle: Dose-effect Relationship of Tai Chi on Health Promotion in Different Age Groups overallStatus: COMPLETED date: 2023-08-25 date: 2023-11-25 date: 2023-11-25 date: 2024-03-12 date: 2024-03-26 name: Beijing Sport University class: OTHER briefSummary: The purpose of... |
<|newrecord|> nctId: NCT06307470 id: 276879 briefTitle: Nurse-led Mind-body Intervention on Sexual Health for Breast Cancer Survivors overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-05-30 date: 2024-05-30 date: 2024-03-12 date: 2024-03-20 name: University of Arkansas class: OTHER name: Intimate Pathways C... |
1. What is the feasibility of this intervention in an online, private setting? |
2. What is the effect of this intervention on reducing menopausal symptoms, improving sexual functioning, and enhancing body image? |
Participants will participate in a nurse-led psychoeducational intervention for 8 sessions lasting approximately an hour each over the course of 8 - 10 weeks. Each participant will complete survey items at the beginning, end, and six-weeks after the last session. Participants will be compensated up to $150 in gift card... |
<|newrecord|> nctId: NCT06307457 id: A5481188 briefTitle: A Study of HR+/HER2- Metastatic Breast Cancer Patients Treated With Palbociclib Together With an Aromatase Inhibitor From 2017 to 2023 in Denmark. overallStatus: ACTIVE_NOT_RECRUITING date: 2024-03-06 date: 2024-08-31 date: 2024-08-31 date: 2024-03-12 date: 2024... |
* have advanced or metastatic breast cancer that is spread to other parts of the body. |
* have HR+/HER2- (hormone receptor positive\* / human epidermal growth factor receptor 2 negative\*\*) breast cancer types. |
* Hormone receptor positive (HR+): are cells that have a group of proteins that bind to a specific hormone. For example, some breast cancer cells have receptors for the hormones estrogen or progesterone. |
These cells are hormone receptor positive, and they need estrogen or progesterone to grow. This can affect how the cancer is treated. Knowing if the cancer is hormone receptor positive may help plan treatment. |
* Human epidermal growth factor receptor 2 negative (HER2-): cells that have a small amount or none of a protein called HER2 on their surface. In normal cells, HER2 helps control cell growth. Cancer cells that are HER2 negative may grow more slowly and are less likely to recur (come back) or spread to other parts of th... |
* have started treatment in the period between January 2017 and December 2021. |
The study will describe the treatment effect for different patient groups in terms of age and comorbidities. Comorbidity is the condition of having two or more diseases at the same time. The data is collected by the Danish Breast Cancer Group in the period between 2017 to 2023. conditions: Breast Cancer studyType: OBSE... |
<|newrecord|> nctId: NCT06307444 id: stellate block and ESP block briefTitle: Ultrasound-Guided Erectro Spinae Plane Block Versus Stellate Ganglion Block for Patients With Upper Limb Acute Herpes Zoster Pain. overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-10-01 date: 2024-11-01 date: 2024-03-12 date: 202... |
<|newrecord|> nctId: NCT06307431 id: V940-004 id: 2023-505177-32 type: OTHER domain: EU CT briefTitle: A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004) overallStatus: RECRUITING date: 2024-04-10 date: 2028-01-08 date: 2032-06-08 date: 2024-03-12 date: 2024-04-29 name: Merck Sharp & Dohme LL... |
<|newrecord|> nctId: NCT06307418 id: Carer eSupport RCT briefTitle: Internet-based Support for Informal Caregivers of Patients With Head and Neck Cancer - Carer eSupport overallStatus: NOT_YET_RECRUITING date: 2024-05-06 date: 2025-10-31 date: 2025-10-31 date: 2024-03-12 date: 2024-04-01 name: Uppsala University class:... |
* What are the effects of internet-based support on informal caregivers preparedness for caregiving? |
* What are the effects of internet-based support on informal caregivers burden and wellbeing? |
Informal caregivers who are randomized to Carer eSupport will have access to Carer eSupport for 18 weeks and they will be asked to complete questionnaires (outcome measures) at: |
* baseline (before randomization) |
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