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* 18 weeks (post-intervention) and at |
* 3 months after the intervention is completed (long term follow-up). |
Informal caregivers in the intervention group will be compared to informal caregivers who receive standard care support regarding preparedness for caregiving, caregiver burden and wellbeing. conditions: Head and Neck Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interven... |
<|newrecord|> nctId: NCT06307405 id: WJP2023 briefTitle: The Value of mNGS in Diagnosis of Pulmonary Infection overallStatus: NOT_YET_RECRUITING date: 2024-04-20 date: 2025-04-20 date: 2025-09-30 date: 2024-03-12 date: 2024-03-12 name: Yunfeng Hou class: OTHER briefSummary: Retrospective analysis of clinical data from ... |
<|newrecord|> nctId: NCT06307392 id: RC22_0393 briefTitle: Bougie Versus Endotracheal Tube Alone on First-attempt Intubation Success in Prehospital Emergency Intubation (BETA Trial) acronym: BETA overallStatus: RECRUITING date: 2024-03-26 date: 2027-03-26 date: 2027-03-31 date: 2024-03-12 date: 2024-04-05 name: Nantes ... |
<|newrecord|> nctId: NCT06307379 id: EC 23022 briefTitle: Patient Reported Outcome and Experience Measures for Bronchoscopic Procedures acronym: BRONCHOPROEM overallStatus: RECRUITING date: 2024-02-13 date: 2025-12-30 date: 2025-12-30 date: 2024-03-12 date: 2024-03-12 name: Vitaz class: OTHER briefSummary: 'Patient-rep... |
Validated disease-specific PROMS related to bronchoscopic procedures are not available and examples in the medical literature are very scarce. conditions: Bronchial Diseases studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 300 type: ESTIMATED name: no intervention measure: Procedu... |
<|newrecord|> nctId: NCT06307366 id: ErasmusMC10365 briefTitle: Perceptions and Experiences of (Family Members of) People With Mental Illness About the Chance for Mental Illness in (Future) Children, and Needs for Care and Research acronym: PANDAcc overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-06 date: 202... |
<|newrecord|> nctId: NCT06307353 id: Soh_Med_23_12_05MS briefTitle: Trends of Contraception Methods in Urban Medical Center in el_Balyana overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-10-01 date: 2025-03-01 date: 2024-03-12 date: 2024-03-12 name: Sohag University class: OTHER briefSummary: family planni... |
<|newrecord|> nctId: NCT06307340 id: 22-01058 briefTitle: Adaption of the STAIR-NT Trauma Intervention for Polysubstance Populations overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2025-10 date: 2024-03-12 date: 2024-04-04 name: NYU Langone Health class: OTHER name: National Institute on Drug Abuse ... |
<|newrecord|> nctId: NCT06307327 id: NFEC-2024-098 briefTitle: Comparative Study of New Classification and Traditional Classification of Radioactive Oropharyngeal Mucositis overallStatus: RECRUITING date: 2024-03 date: 2025-12 date: 2026-12 date: 2024-03-12 date: 2024-03-26 name: Nanfang Hospital, Southern Medical Univ... |
<|newrecord|> nctId: NCT06307314 id: NFEC-2024-093 briefTitle: Plasma SAA1 Levels in Predicting Response to Radiotherapy-induced Oral Mucositis overallStatus: RECRUITING date: 2024-02-01 date: 2026-12-01 date: 2026-12-31 date: 2024-03-12 date: 2024-03-12 name: Nanfang Hospital, Southern Medical University class: OTHER ... |
<|newrecord|> nctId: NCT06307301 id: PRO00031998 briefTitle: Study in ALS With Abatacept & IL-2 overallStatus: ACTIVE_NOT_RECRUITING date: 2021-10-28 date: 2024-10-17 date: 2024-10-17 date: 2024-03-12 date: 2024-04-16 name: The Methodist Hospital Research Institute class: OTHER briefSummary: In Amyotrophic Lateral Scle... |
<|newrecord|> nctId: NCT06307288 id: 20240301-2 briefTitle: Efficacy and Safety of Tranilast Combined With Minocycline in the Treatment of Rosacea overallStatus: ENROLLING_BY_INVITATION date: 2023-10-16 date: 2024-06-01 date: 2024-06-01 date: 2024-03-12 date: 2024-03-12 name: Second Affiliated Hospital of Xi'an Jiaoton... |
<|newrecord|> nctId: NCT06307275 id: 5170221 briefTitle: Intermittent Fasting on Body Fat and Quality of Life overallStatus: RECRUITING date: 2024-03-11 date: 2024-12-31 date: 2024-12-31 date: 2024-03-12 date: 2024-04-12 name: Loma Linda University class: OTHER briefSummary: The purpose of this investigator-initiated s... |
<|newrecord|> nctId: NCT06307262 id: EuroTR Registry briefTitle: European Registry of Transcatheter Repair for Tricuspid Regurgitation acronym: EuroTR overallStatus: RECRUITING date: 2023-10-23 date: 2030-12-31 date: 2030-12-31 date: 2024-03-12 date: 2024-03-15 name: LMU Klinikum class: OTHER briefSummary: To investiga... |
<|newrecord|> nctId: NCT06307249 id: LU_HH_Cancer_Precision Therapy briefTitle: Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA acronym: PTST_PALBEVA overallStatus: RECRUITING date: 2023-02-15 date: 2025-12 date: 2027-12 date: 2024-03-12 date: 2024-03-12 name: Lebanese U... |
<|newrecord|> nctId: NCT06307236 id: E-41997688-050.99-105442 briefTitle: Dysmenorrhea of Emotional Freedom Techniques (EFT) and Its Effect on Perceived Stress Level overallStatus: ENROLLING_BY_INVITATION date: 2023-12-15 date: 2024-04-15 date: 2024-04-15 date: 2024-03-12 date: 2024-03-12 name: Kutahya Health Sciences ... |
<|newrecord|> nctId: NCT06307223 id: 20240301 briefTitle: Efficacy and Safety of 30% Supramolecular Salicylic Acid Combined With Supramolecular Active Zinc in the Treatment of Malassezia Folliculitis overallStatus: COMPLETED date: 2022-06-07 date: 2023-09-20 date: 2023-09-20 date: 2024-03-12 date: 2024-03-12 name: Seco... |
<|newrecord|> nctId: NCT06307210 id: coreset_2020_2022 briefTitle: Is Inpatient Rehabilitation Effective for Very Old Patients? overallStatus: COMPLETED date: 2020-01-01 date: 2022-12-31 date: 2023-01-01 date: 2024-03-12 date: 2024-03-12 name: Klinik Valens class: OTHER briefSummary: The goal of this retrospective long... |
The main question it aims to answer is: Do very old patients benefit in a similar way from inpatient rehabilitation like younger patients? Data from about 2000 patients will be retrospectively analyzed. Functional Independence Measurement (FIM), Timed Up and Go Test (TUG), EuroQol 5 Dimensions (EQ-5D) and Patient Repor... |
Researchers will compare the age group 75 to 84 and 85 to 99 to see if physical and mental performance as well as quality of life will improve. conditions: Activity, Motor conditions: Elderly Patients conditions: Musculoskeletal Diseases studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE... |
<|newrecord|> nctId: NCT06307197 id: INRCA_008_2023 briefTitle: HAAL: HeAlthy Ageing Eco-system for peopLe With Dementia acronym: HAAL overallStatus: RECRUITING date: 2023-10-02 date: 2024-04-15 date: 2024-04-15 date: 2024-03-12 date: 2024-03-12 name: Istituto Nazionale di Ricovero e Cura per Anziani class: OTHER brief... |
<|newrecord|> nctId: NCT06307184 id: 2301-LIS-007-AN briefTitle: Assessing the Convenience of Natural Proliferative Phase Frozen Embryo Transfer overallStatus: RECRUITING date: 2024-02-23 date: 2024-10 date: 2025-07 date: 2024-03-12 date: 2024-03-12 name: Instituto Valenciano de Infertilidade de Lisboa class: NETWORK n... |
<|newrecord|> nctId: NCT06307171 id: 2023-11 briefTitle: Human Leishmaniasis: Antigen Recognition Pattern and Study of New Potential Biomarkers acronym: LeishmARPs overallStatus: RECRUITING date: 2023-05-22 date: 2026-11 date: 2026-11 date: 2024-03-12 date: 2024-03-12 name: IRCCS Sacro Cuore Don Calabria di Negrar clas... |
General objectives of the study are: to identify specific biomarkers in order to develop more accurate serological tests for the screening of Leishmania infections that does not present cross-reaction with other infectious diseases; to unveil the Antigen Recognition Patterns (ARPs) of Leishmania infection in humans; to... |
<|newrecord|> nctId: NCT06307158 id: CT2024-ZJU-OBS1 briefTitle: Influence of Intraoperative Blood Salvage and Autotransfusion on Tumor Recurrence After Deceased Donor Liver Transplantation overallStatus: COMPLETED date: 2015-01-01 date: 2020-12-31 date: 2021-12-31 date: 2024-03-12 date: 2024-03-12 name: Zhejiang Unive... |
<|newrecord|> nctId: NCT06307145 id: K-NHIS-HIP briefTitle: Korea Hip Replacement Surgery Registry overallStatus: COMPLETED date: 2003-01-01 date: 2020-12-31 date: 2020-12-31 date: 2024-03-12 date: 2024-03-12 name: Samsung Medical Center class: OTHER briefSummary: This cohort study obtained data from the Korean Nationa... |
<|newrecord|> nctId: NCT06307132 id: SAHoWMU-CR2024-03-106 briefTitle: Drug Metabolism, Excretion, and Human Body Composition of Aximus Capsules overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-31 date: 2024-06-30 date: 2024-08-31 date: 2024-03-12 date: 2024-03-12 name: Second Affiliated Hospital of Wenzhou Medical U... |
<|newrecord|> nctId: NCT06307119 id: 2020-01 briefTitle: Model of Human Occupation-Based Intervention on Premenstrual Syndrome Symptoms overallStatus: COMPLETED date: 2023-03-01 date: 2024-03-01 date: 2024-03-02 date: 2024-03-12 date: 2024-03-12 name: Saglik Bilimleri Universitesi class: OTHER briefSummary: This study ... |
<|newrecord|> nctId: NCT06307106 id: #40\14-Jan-2024 briefTitle: Various Strategies to Reduce Acute Post Hemorrhoidectomy Pain: A Comparative Study overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-14 date: 2024-07-14 date: 2024-07-14 date: 2024-03-12 date: 2024-03-12 name: Zagazig University class: OTHER_GOV briefSum... |
<|newrecord|> nctId: NCT06307093 id: CL01860198 briefTitle: Study Comparing the Pharmacokinetics, Safety, and Efficacy of RPH-075 and Keytruda® in Patients With Malignant Neoplasms overallStatus: ACTIVE_NOT_RECRUITING date: 2023-03-01 date: 2023-12-11 date: 2025-07 date: 2024-03-12 date: 2024-03-12 name: R-Pharm class:... |
The main main tasks are: |
* To evaluate and compare the pharmacokinetic properties of RPH-075 and Keytruda® after a single intravenous administration of pembrolizumab to patients with malignant neoplasms; |
* To evaluate the safety profile of the drug RPH-075 in comparison with the drug Keytruda® when used in patients with malignant neoplasms when used as a 1st or 2nd line therapy in a monotherapy regimen. |
This study will also include a comparative assessment of immunogenicity, pharmacodynamic parameters and a pilot evaluation of RPH-075 efficacy. conditions: Skin Melanoma conditions: Squamous Non-small-cell Lung Cancer conditions: Head and Neck Squamous Cell Carcinoma studyType: INTERVENTIONAL phases: PHASE1 allocation:... |
<|newrecord|> nctId: NCT06307080 id: IIT2023-064 briefTitle: Clinical Study of Multi-mode Thermal Ablation for the Treatment of Pancreatic Cancer With Liver Metastasis overallStatus: RECRUITING date: 2023-10-08 date: 2024-12-31 date: 2024-12-31 date: 2024-03-12 date: 2024-03-12 name: Shanghai General Hospital, Shanghai... |
2. Construction of a combined treatment system of multimodal ablation therapy combined with immunotherapy and chemotherapy. |
3. Transformation and clinical application of multimodal ablation system for pancreatic cancer with hepatic metastatic malignancies. conditions: Pancreatic Cancer studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 12 type: ESTIMATED nam... |
<|newrecord|> nctId: NCT06307067 id: URINDO briefTitle: Improving Care for Uncomplicated URinary Tract Infection-associated Symptoms in Primary Healthcare Settings in INDOnesia acronym: URINDO overallStatus: NOT_YET_RECRUITING date: 2024-03-04 date: 2024-11-04 date: 2025-06-01 date: 2024-03-12 date: 2024-03-12 name: Er... |
Specific aims of the study: |
1. To analyze the quality of antibiotic prescriptions for uncomplicated UTI in the primary health care settings in Indonesia, before introduction of urinary dipstick testing compared to after introduction of urinary dipstick testing. |
2. To analyze the knowledge level of healthcare workers on uncomplicated UTI and prudent antibiotic use in primary health care settings in Indonesia. conditions: Urinary Tract Infections studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: PROSPECTIVE count: 300 type: ESTIMATED name: Urine dipstick measu... |
<|newrecord|> nctId: NCT06307054 id: SHSY-CAR-NK-AML01 briefTitle: CLL-1 CAR-NK Cells for Relapsed/Refractory AML overallStatus: RECRUITING date: 2024-03-15 date: 2026-03-15 date: 2027-03-15 date: 2024-03-12 date: 2024-03-12 name: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine class: OTHER ... |
<|newrecord|> nctId: NCT06307041 id: OSATAGUN briefTitle: Effects of 0.2% Hyaluronic Acid Gel-Impregnated Dental Flosses on Clinical Gingival Parameters overallStatus: COMPLETED date: 2023-04-03 date: 2023-07-07 date: 2023-08-11 date: 2024-03-12 date: 2024-03-12 name: Özlem SARAÇ ATAGÜN class: OTHER briefSummary: This ... |
<|newrecord|> nctId: NCT06307028 id: Pro2023002116 id: K01DA050496 type: NIH link: https://reporter.nih.gov/quickSearch/K01DA050496 briefTitle: Sistas Informing Sistas on Topics About AIDS and Prevention (SISTA-P) acronym: SISTA-P overallStatus: RECRUITING date: 2024-01-08 date: 2024-07-01 date: 2024-08-31 date: 2024-0... |
<|newrecord|> nctId: NCT06307015 id: 2023/ETH02441 briefTitle: De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE) acronym: DE-RADIATE overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2027-12 date: 2031-12 date: 2024-03-12 date: 2024-03-12 name: Royal North Shore Hospital class: ... |
The main questions it aims to answer are: |
1. What is the pathologic complete response rate in patients selected for radiation dose de-escalation and neck dissection? |
2. What is the correlation between MRI and FMISO PET assessment of hypoxia before and during RT? |
3. What are the acute and late toxicities in patients selected for radiation dose de-escalation? |
4. What are the quality of life scores in patients selected for radiation dose de-escalation? |
5. What are the local, regional and distant failure rates of patients selected for radiation dose de-escalation? |
Patients with cT1-2N1-2b (AJCC 7th edition) oropharyngeal tumours will undergo surgical resection of the primary tumour. Following this, they will be allocated to standard radiation therapy (70Gy with concurrent cisplatin chemotherapy) or de-escalation radiation therapy (30Gy with concurrent cisplatin chemotherapy) bas... |
Researchers will assess the pathologic response rate after surgery in the de-escalation group. They will also compare the outcomes (oncological outcomes and quality of life) between the group receiving the standard treatment (70Gy) and the group receiving de-escalated radiation therapy (30Gy). conditions: HPV Positive ... |
<|newrecord|> nctId: NCT06307002 id: CAS_EB_2024 briefTitle: Evaluating What's My Method? in Barbados overallStatus: RECRUITING date: 2024-03-11 date: 2024-06-15 date: 2024-07-30 date: 2024-03-12 date: 2024-03-15 name: Quinnipiac University class: OTHER name: Barbados Family Planning Association briefSummary: The purpo... |
<|newrecord|> nctId: NCT06306989 id: Zhengzhou University briefTitle: Observational Clinical Study of Letermovir for Preventing CMV Infection After Allo-HSCT overallStatus: RECRUITING date: 2023-01-01 date: 2024-09-01 date: 2025-12-01 date: 2024-03-12 date: 2024-03-12 name: Cao Weijie class: OTHER briefSummary: The goa... |
* Efficacy and safety of letemovir for the prevention of CMV infection after allo-HSCT. |
* Optimal initiation of letemovir to prevent CMV infection. Participants will be categorized into high-risk and intermediate-risk groups based on risk factors for CMV infection.Initiate letemovir prophylaxis on day +1 in high-risk patients and on days +7 to +14 in non-high-risk patients.(240 mg, qd in patients with con... |
<|newrecord|> nctId: NCT06306976 id: 2066031 briefTitle: Shear-Wave Elastography acronym: ELASTOGRAPHY overallStatus: ENROLLING_BY_INVITATION date: 2024-03 date: 2024-07 date: 2025-08 date: 2024-03-12 date: 2024-03-13 name: Prisma Health-Upstate class: OTHER briefSummary: Prospective cohort study of patients with midli... |
Study groups: Study groups are selected across a range of morphology and based on factors known or suspected to affect the ability to achieve fascial closure. |
Control groups: The study plans to enlist 5 volunteers with no incisional hernia or prior laparotomy to establish internal baseline SWE values and interrater reliability. The study will also plan to recruit 5 patients undergoing primary laparotomy in order to correlate SWE findings with closure tension. conditions: Ven... |
Determine the elasticity of abdominal wall muscles (rectus abdominis, external oblique, internal oblique, and transversus abdominis) through shear wave elastography in patients with midline incisional hernias of varying complexity and morphology. |
Specific Aim 2: |
Correlate shear wave elastography measurements of the abdominal wall with the extent of MFR required to achieve fascial closure. |
Specific Aim 3: |
Correlate SWE-determined elasticity of abdominal wall to intraoperative assessment of tension required to achieve fascial closure. primaryPurpose: OTHER masking: NONE count: 70 type: ESTIMATED name: Elective Midline Laparotomy name: Imaging: Ultrasound name: Tensiometry measure: Determine Elasticity of Abdominal Wall M... |
<|newrecord|> nctId: NCT06306963 id: 23-004669 briefTitle: Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias acronym: GAVE overallStatus: RECRUITING date: 2024-03-22 date: 2026-03-01 date: 2026-09-01 date: 2024-03-12 date: 2024-04-26 name: Mayo Clinic class: OTHER briefSu... |
<|newrecord|> nctId: NCT06306950 id: PMK-00098 briefTitle: Prioritization of Cerebral Deoxygenation in Severe Traumatic Brain Injury and Mortality Benefit. overallStatus: COMPLETED date: 2021-04-01 date: 2024-02-28 date: 2024-02-28 date: 2024-03-12 date: 2024-03-15 name: Phramongkutklao College of Medicine and Hospital... |
<|newrecord|> nctId: NCT06306937 id: A24020822 briefTitle: Serum Levels of Vitamin D and IL8 in Patients With Periodontitis overallStatus: COMPLETED date: 2022-09-01 date: 2023-09-30 date: 2023-09-30 date: 2024-03-12 date: 2024-03-12 name: Mansoura University class: OTHER briefSummary: We evaluated vitamin D and IL8 le... |
<|newrecord|> nctId: NCT06306924 id: LCCC2303 briefTitle: UNC Metastatic Cancer Radiation Therapy Registry overallStatus: RECRUITING date: 2024-04-21 date: 2033-05 date: 2033-05 date: 2024-03-12 date: 2024-04-26 name: UNC Lineberger Comprehensive Cancer Center class: OTHER briefSummary: The purpose of this registry is ... |
<|newrecord|> nctId: NCT06306911 id: BB-BAM briefTitle: Bioavailability of Aronia Melanocarpa overallStatus: RECRUITING date: 2024-03 date: 2024-07 date: 2024-07 date: 2024-03-12 date: 2024-03-12 name: Maastricht University Medical Center class: OTHER name: BioActor briefSummary: The main objective of this study is to ... |
<|newrecord|> nctId: NCT06306898 id: IAV-2024-01 briefTitle: Intra-Arrest-Ventilation in Human Cadavers overallStatus: NOT_YET_RECRUITING date: 2024-03-18 date: 2024-10-31 date: 2024-12-31 date: 2024-03-12 date: 2024-03-19 name: Gerrit Jansen class: OTHER name: Ruhr University of Bochum name: Bielefeld University brief... |
<|newrecord|> nctId: NCT06306885 id: CLF23/03 briefTitle: Effects of Early Sleep After Action Observation and Motor Imagery After Metacarpal Fracture Surgery overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-09-01 date: 2025-05-01 date: 2024-03-12 date: 2024-03-12 name: Istituto Clinico Humanitas class: OTH... |
Fifty-one patients with hand immobilization for surgical fixation of IV or V metacarpals or first phalanges fractures will be randomized into AOMI-sleep (n=17), AOMI-control (n=17), and Control (n=17) group. AOMI-sleep and AOMI-control groups will perform an AOMI-training before sleeping or in the morning respectively,... |
<|newrecord|> nctId: NCT06306872 id: ABSK-011-102 briefTitle: A Clinical Trial to Evaluate the Relative Bioavailability of New and Old ABSK-011 Capsules overallStatus: RECRUITING date: 2024-02-23 date: 2024-12-31 date: 2024-12-31 date: 2024-03-12 date: 2024-03-12 name: Abbisko Therapeutics Co, Ltd class: INDUSTRY brief... |
<|newrecord|> nctId: NCT06306859 id: SIKIDI 2024 briefTitle: Development of Health Monitoring System on Patient's Well Being in Dialysis Context acronym: SIKIDI overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2024-10-31 date: 2024-12-31 date: 2024-03-12 date: 2024-03-12 name: Universitas Muhammadiyah Yogyakart... |
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