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<|newrecord|> nctId: NCT06306001 id: IIRP-2023-1820/F1 briefTitle: Intravenous Methylene Blue for Treating Refractory Neonatal Septic Shock overallStatus: NOT_YET_RECRUITING date: 2024-03-15 date: 2026-03-14 date: 2027-02 date: 2024-03-12 date: 2024-03-12 name: Post Graduate Institute of Medical Education and Research,... |
1. Whether MB treatment reduces death to any cause as compared to no MB treatment. |
2. Whether treatment with MB reduces the time to achieve normal blood pressure |
3. Whether treatment with MB reduces the time to stoppage of all blood pressure medications, steroids and normal saline. |
4. Whether treatment with MB improves heart function as measured by echocardiography at 24 and 48 hours. conditions: Neonatal Sepsis conditions: Shock, Septic studyType: INTERVENTIONAL phases: PHASE2 phases: PHASE3 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Subjects will be randoml... |
<|newrecord|> nctId: NCT06305988 id: LYG2023021 briefTitle: Neuroregulatory Effect and Mechanism of tDCS on Medial Prefrontal Cortex in ASD overallStatus: RECRUITING date: 2023-08-01 date: 2024-07-31 date: 2024-07-31 date: 2024-03-12 date: 2024-03-15 name: Jian-Jun Ou class: OTHER briefSummary: In this proposed study, ... |
<|newrecord|> nctId: NCT06305975 id: STUDY00003169 briefTitle: Blunt Fascial vs. Veress Needle Peritoneal Entry in Laparoscopic Gynecologic Surgery acronym: BluntFascial overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03-01 date: 2025-03-01 date: 2024-03-12 date: 2024-03-12 name: Cedars-Sinai Medical Center ... |
The investigators hypothesize that the blunt entry technique will be associated with shorter insufflation times and similar intraoperative and postoperative outcomes compared with the veress needle entry technique. |
Primary Objective: To evaluate the insufflation times and success upon peritoneal entry according to peritoneal entry technique. |
Secondary Objectives: To evaluate the surgical outcomes and patients pain scores according to peritoneal entry technique. conditions: Laparoscopic Surgery studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 100 type: ESTIMATED name: Blun... |
<|newrecord|> nctId: NCT06305962 id: 177Lu-RAD204.2023.0001 briefTitle: 177Lu-anti-PD-L1 sdAb in Metastatic Non-small Cell Lung Cancer overallStatus: RECRUITING date: 2024-03 date: 2025-07 date: 2025-10 date: 2024-03-12 date: 2024-03-26 name: Radiopharm Theranostics, Ltd class: INDUSTRY briefSummary: This is a first-in... |
<|newrecord|> nctId: NCT06305949 id: XC23DDDS0098 briefTitle: Clinical Trial on the Safety and Efficacy of Optimized Transcranial Direct Current Stimulation for the Swallowing Function in Patients With Post-Stroke Dysphagia overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-07-31 date: 2025-12-31 date: 2024-... |
<|newrecord|> nctId: NCT06305936 id: PLATE H-23042292 briefTitle: Feasibility Study: Plant Based Diet to Patients With Rheumatoid Arthritis acronym: PLATE overallStatus: RECRUITING date: 2024-02-15 date: 2024-07-31 date: 2024-12-31 date: 2024-03-12 date: 2024-03-15 name: Bispebjerg Hospital class: OTHER name: Glostrup ... |
Adopting a daily plant-based diet involves introducing several new plant-based foods and making adjustments to the existing diets of patients with RA. Consequently, the feasibility study will also aim to explore the acceptability of the intervention and whether a full-scale RCT is practically possible. conditions: Rheu... |
<|newrecord|> nctId: NCT06305923 id: RNN/275/21/KE id: 503/3-066-02/503-31-001 type: OTHER_GRANT domain: Medical University of Lodz briefTitle: The Efficacy of a Cosmetic Preparation Containing Sheep Colostrum on Mature Skin acronym: COLMATSKIN overallStatus: COMPLETED date: 2022-03-01 date: 2022-06-30 date: 2022-07-31... |
Participants will be enrolled to the colostrum cream or base cream groups and will not be informed which group they belonged to. conditions: Skin Aging studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: BASIC_SCIENCE masking: SINGLE whoMasked: PARTICIPANT count: 52 t... |
<|newrecord|> nctId: NCT06305910 id: CMN-DMGVac-01 briefTitle: CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults overallStatus: RECRUITING date: 2024-03-15 date: 2025-09-15 date: 2027-01-15 date: 2024-03-12 date: 2024-03-12 name: OX2 ... |
The primary objective of this study is to determine the maximum tolerated dose (MTD) of CD200AR-L when given with a fixed dose of GBM6-AD vaccine, imiquimod, and a single dose of radiation for patients with recurrent High Grade Glioma (HGG) or following standard of care therapy radiation therapy for newly diagnosed New... |
<|newrecord|> nctId: NCT06305897 id: CS5_10B briefTitle: Evaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the Face acronym: CS5_10B overallStatus: NOT_YET_... |
* the tolerance of 3 prototypes of cyto-selective cryotherapy treatments |
* the performance of 3 prototypes of cyto-selective cryotherapy treatments |
Participants will be treated for each spots with a definied prototype during 6 treatment visits. |
Researchers will compare the tolerance and performance of the 3 prototypes. conditions: Lentigo conditions: Solar Lentigo conditions: Post Inflammatory Hyperpigmentation studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Proof of concept study concernin... |
<|newrecord|> nctId: NCT06305884 id: OSU-21287 id: NCI-2023-03077 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) briefTitle: Transcutaneous Sensors for the Detection of Cancer-Related Lymphedema, Project Limb Rescue Study overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2025-12-31 date: 2025-12-... |
<|newrecord|> nctId: NCT06305871 id: 2023-NHLHCRF-YYPPLC-ZR-09 briefTitle: Clinical Study of Ultrasound-guided Radiofrequency Ablation in the Treatment of Refractory Hyperthyroidism overallStatus: ACTIVE_NOT_RECRUITING date: 2023-08-01 date: 2025-07-31 date: 2025-07-31 date: 2024-03-12 date: 2024-03-12 name: Zhang Bo c... |
The expected outcome of this study is to establish a research cohort of hyperthyroidism ablation based on a large sample population, and to establish the most appropriate and effective regimen for radiofrequency ablation of refractory hyperthyroidism compared with traditional surgery and 131I treatment with safety and ... |
<|newrecord|> nctId: NCT06305858 id: UKA - PFJ briefTitle: Partial Versus Total Knee Replacement in Bicompartmental Gonarthrosis (Medial and Patellofemoral): Prospective Functional Assessment Study overallStatus: RECRUITING date: 2022-03-01 date: 2025-09 date: 2025-12 date: 2024-03-12 date: 2024-03-12 name: I.R.C.C.S O... |
The aim of the study is to evaluate the post-operative recovery of the group A patient undergoing the partial knee replacement surgical procedure compared to the group B patient undergoing the total knee replacement surgical procedure through clinical/functional scores. |
The primary outcome is evaluate the difference in score of the KSS questionnaire, at 1 month after surgery, completed by the patient of group A compared to the patient of group B. |
The population consists of 48 adult patients with gonarthrosis divided into two groups: |
24 patients Group A experimental group: partial denture surgical procedure |
24 patients Group B control group: total denture surgical procedure with patellar resurfacing conditions: Knee Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: PARTICIPANT count: 48 type: ESTIMATED name: Prosthetic... |
<|newrecord|> nctId: NCT06305845 id: 152012023 briefTitle: Digital Crowns Versus Prefabricated Crowns on Primary Teeth overallStatus: ACTIVE_NOT_RECRUITING date: 2023-06-01 date: 2023-09-20 date: 2024-09 date: 2024-03-12 date: 2024-03-12 name: National Research Centre, Egypt class: OTHER briefSummary: Badly decayed pri... |
<|newrecord|> nctId: NCT06305832 id: IUNU-PC-120 briefTitle: Salvage Radiotherapy Combined With Androgen Deprivation Therapy (ADT) With or Without Rezvilutamide in the Treatment of Biochemical Recurrence After Radical Prostatectomy for Prostate Cancer overallStatus: RECRUITING date: 2023-09-07 date: 2028-03 date: 2028-... |
<|newrecord|> nctId: NCT06305819 id: 2023057 briefTitle: Effectiveness of a Self-management Program After Traumatic Injury acronym: SEMPO overallStatus: RECRUITING date: 2024-01-01 date: 2030-12-31 date: 2030-12-31 date: 2024-03-12 date: 2024-04-12 name: Oslo University Hospital class: OTHER name: South-Eastern Norway ... |
The main goal of this study is to determine the effectiveness of a self-management support program delivered to persons with a moderate or severe traumatic injury in the sub-acute phase of recovery (i.e. 3-4 months after injury). The self-management program aims to enhance patients' self-efficacy by building skills and... |
<|newrecord|> nctId: NCT06305806 id: Pro00112597_B id: OTA-21-015G type: OTHER domain: NIH Grant to RTI; RTI subcontracting with DCRI briefTitle: RECOVER-AUTONOMIC: Platform Protocol, Appendix B (Ivabradine) overallStatus: ENROLLING_BY_INVITATION date: 2024-03-11 date: 2025-12 date: 2026-03 date: 2024-03-12 date: 2024-... |
This protocol is a prospective, multi-center, multi-arm, randomized, controlled platform trial evaluating various interventions for use in the treatment of autonomic dysfunction symptoms, including cardiovascular complications and postural orthostatic tachycardia syndrome (POTS), in PASC participants. The interventions... |
<|newrecord|> nctId: NCT06305793 id: Pro00112597_A id: OTA-21-015G type: OTHER domain: NIH Grant to RTI; RTI subcontracting with DCRI briefTitle: RECOVER-AUTONOMIC: Platform Protocol, Appendix A (IVIG) overallStatus: ENROLLING_BY_INVITATION date: 2024-03-11 date: 2025-12 date: 2026-03 date: 2024-03-12 date: 2024-04-08 ... |
This protocol is a prospective, multi-center, multi-arm, randomized, controlled platform trial evaluating various interventions for use in the treatment of autonomic dysfunction symptoms, including cardiovascular complications and postural orthostatic tachycardia syndrome (POTS), in Post-Acute Sequelae of SARS-CoV-2 in... |
<|newrecord|> nctId: NCT06305780 id: Pro00112597 id: OTA-21-015G type: OTHER domain: NIH Grant to RTI; RTI subcontracting with DCRI briefTitle: RECOVER-AUTONOMIC Platform Protocol overallStatus: ENROLLING_BY_INVITATION date: 2024-03-11 date: 2025-12 date: 2026-03 date: 2024-03-12 date: 2024-04-08 name: Kanecia Obie Zim... |
This protocol is a prospective, multi-center, multi-arm, randomized, controlled platform trial evaluating various interventions for use in the treatment of autonomic dysfunction symptoms, including cardiovascular complications and postural orthostatic tachycardia syndrome (POTS), in PASC participants. The interventions... |
<|newrecord|> nctId: NCT06305767 id: V940-005 id: V940-005 type: OTHER domain: Merck id: U1111-1292-1952 type: OTHER domain: WHO id: 2023-505658-17 type: OTHER domain: EU CT briefTitle: A Study of Pembrolizumab (MK-3475) Plus V940 in Participants With Bladder Cancer Post-Radical Resection (V940-005) overallStatus: RECR... |
<|newrecord|> nctId: NCT06305754 id: 2870-009 id: 2023-504910-31 type: REGISTRY domain: EU CT id: U1111-1288-3804 type: OTHER domain: UTN id: MK-2870-009 type: OTHER domain: Merck briefTitle: Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Fa... |
The primary hypotheses of this study are that sacituzumab tirumotecan is better than platinum-based doublet chemotherapy (pemetrexed and carboplatin) in regard to progression-free survival (PFS) and overall survival (OS). conditions: Non-small Cell Lung Cancer (NSCLC) studyType: INTERVENTIONAL phases: PHASE3 allocation... |
<|newrecord|> nctId: NCT06305741 id: 24-060 briefTitle: A Study of an Anxiety Intervention for Latino/Latina/Hispanic Older Adults With Cancer and Their Caregivers overallStatus: RECRUITING date: 2024-03-05 date: 2026-03 date: 2026-03 date: 2024-03-12 date: 2024-03-12 name: Memorial Sloan Kettering Cancer Center class:... |
<|newrecord|> nctId: NCT06305728 id: 23-367 briefTitle: A Study of Early Cancer Detection in People at High Risk of Developing Pancreatic Ductal Adenocarcinoma (PDAC) overallStatus: RECRUITING date: 2024-03-04 date: 2030-03-04 date: 2030-03-04 date: 2024-03-12 date: 2024-03-12 name: Memorial Sloan Kettering Cancer Cent... |
* The ImmunoPET scan (immune-positron emission tomography scan) with the imaging agent 89Zr-DFO-HuMab-5B1 |
* The HP MRI scan (hyperpolarized pyruvate magnetic resonance imaging scan) conditions: Pancreatic Cyst studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 25 type: ESTIMATED name: 89Zr-DFO-HuMab-5B1 immunoPET name: HP MRI name: Blood assay measure: Sensitivity of ImmunoPET to identi... |
<|newrecord|> nctId: NCT06305715 id: IIT-THOMPSON-RADIANCE-LUNG-X briefTitle: Radiation Prior to TKI to Delay Progression in Advanced Driver-Mutated Non-small Cell Lung Cancers (RadiaNCe Lung X) overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2027-06-15 date: 2028-06-15 date: 2024-03-12 date: 2024-03-12 name: ... |
<|newrecord|> nctId: NCT06305702 id: LZRXN-001 briefTitle: Real-world Study of Inetetamab in HER2-positive Metastatic Breast Cancer overallStatus: COMPLETED date: 2022-07-01 date: 2023-12-31 date: 2024-01-31 date: 2024-03-12 date: 2024-03-12 name: Liaoning Tumor Hospital & Institute class: OTHER briefSummary: A multice... |
<|newrecord|> nctId: NCT06305689 id: 79144 briefTitle: Defining Treatment Outcomes and Genetic Architecture in Idiopathic Toe Walking* acronym: ITW overallStatus: RECRUITING date: 2022-01-01 date: 2024-07-01 date: 2024-12-31 date: 2024-03-12 date: 2024-04-03 name: Shriners Hospitals for Children class: OTHER briefSumma... |
<|newrecord|> nctId: NCT06305676 id: MCC-23073 briefTitle: Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC) acronym: BASH OPC overallStatus: RECRUITING date: 2024-01-22 date: 2029-01 date: 2029-01 date: 2024-03-12 date: 2024-03-13 name: H. Lee Moffitt Cancer Center ... |
<|newrecord|> nctId: NCT06305663 id: 921 briefTitle: A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children overallStatus: NOT_YET_RECRUITING date: 2024-03-29 date: 2027-01-31 date: 2027-01-31 date: 20... |
<|newrecord|> nctId: NCT06305650 id: WK2024001 briefTitle: Probiotic Influence on Obesity-Related Lipidemia overallStatus: RECRUITING date: 2024-03-20 date: 2024-06-20 date: 2024-07-30 date: 2024-03-12 date: 2024-04-09 name: Wecare Probiotics Co., Ltd. class: INDUSTRY briefSummary: This study aims to investigate the ef... |
<|newrecord|> nctId: NCT06305637 id: KTCS-2302 briefTitle: A Study Comparing Ketoconazole Shampoo, 2% and Ketoconazole 2% Shampoo (RS) in the Treatment of Tinea Versicolor. overallStatus: COMPLETED date: 2023-12-04 date: 2024-02-10 date: 2024-02-10 date: 2024-03-12 date: 2024-03-12 name: Taro Pharmaceuticals USA class:... |
<|newrecord|> nctId: NCT06305624 id: 2024-0130 id: 1R01DA047279-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01DA047279-01 id: A532000 type: OTHER domain: UW Madison id: Protocol Version 2/21/2024 type: OTHER domain: UW Madison briefTitle: Implementation of Mobile-based Programs for Alcohol Cessation in Tr... |
<|newrecord|> nctId: NCT06305611 id: KIWI briefTitle: European and North Indian Cohort of KaWasaki dIsease overallStatus: RECRUITING date: 2021-07-13 date: 2024-07-15 date: 2024-10-30 date: 2024-03-12 date: 2024-03-12 name: Meyer Children's Hospital IRCCS class: OTHER briefSummary: Kawasaki disease (KD) is currently th... |
<|newrecord|> nctId: NCT06305598 id: I-3298823 id: NCI-2024-01390 type: REGISTRY domain: CTRP (Clinical Trial Reporting Program) id: I-3298823 type: OTHER domain: Roswell Park Cancer Institute briefTitle: Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castra... |
<|newrecord|> nctId: NCT06305585 id: IRB# 23-214 briefTitle: Can a Novel Manual Therapy Technique Help Relieve Stress? Assessing Effects of Primal Reflex Release on the Body's Stress Response overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2025-03 date: 2025-03 date: 2024-03-12 date: 2024-03-12 name: University o... |
<|newrecord|> nctId: NCT06305572 id: H-1903-013-1014 briefTitle: Diagnostic Accuracy of Quantitative Flow Ratio overallStatus: COMPLETED date: 2019-07-30 date: 2023-03-25 date: 2023-09-26 date: 2024-03-12 date: 2024-03-12 name: Seoul National University Hospital class: OTHER name: Inje University Ilsan Paik Hospital na... |
<|newrecord|> nctId: NCT06305559 id: OBEZ-302 briefTitle: A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque acronym: REMBRANDT overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-12 date: 2027-03 date: 2024-03-12 date: 2024-03-12 name: NewAmsterdam Pharma class: INDUSTRY bri... |
<|newrecord|> nctId: NCT06305546 id: 2911 briefTitle: Comparisons Of Different Antiplaque Agents On Gingivitis In Orthodontic Patients overallStatus: COMPLETED date: 2023-04-01 date: 2023-10-31 date: 2023-10-31 date: 2024-03-12 date: 2024-03-13 name: Anam Sattar class: OTHER briefSummary: Fixed orthodontic treatment af... |
<|newrecord|> nctId: NCT06305533 id: 854623 briefTitle: Efficacy of Photodynamic Therapy and LASER Disinfection in Periodontal Therapy for Treatment of Periodontitis overallStatus: RECRUITING date: 2024-03-01 date: 2024-09 date: 2024-10 date: 2024-03-12 date: 2024-03-12 name: University of Baghdad class: OTHER briefSum... |
Does the use of laser disinfection or ICG-mediated aPDT as adjunct to RSD are effective in improving clinical parameters and reducing the load of periodontal pathogens. |
Participants will undergo full-mouth supragingival debridement by using ultrasonic device at baseline. |
All patients will be instructed to brush their teeth twice daily and will be supplied with the same type of tooth paste and toothbrush, with suitable interdental aids. |
All the patients will be instructed to attend again after 7 days. One week later, sites randomly allocated to control (Ctrl) group and test groups which will receive, in addition to RSD, either aPDT or periodontal pocket disinfection (Biolase). For all groups, sites with initial PPD 4-6 mm will be treated with RSD usin... |
<|newrecord|> nctId: NCT06305520 id: BPLUS-NASAL-02 id: CRIS NO. : KCT0008113 type: REGISTRY domain: The Clinical Research Information Service (CRIS) in KOREA briefTitle: Medical Device Pivotal Study to Injection With SkinPlus-HYAL Implant Lidocaine vs RESTYLANE Lidocaine in of Nasolabial Folds acronym: BPLUS-02 overal... |
Design : 24-week efficacy and safety evaluation and additional 48-week long-term safety and efficacy evaluation with a multi-center, randomized, subject- \& evaluator-blind, matched pairs, active controlled, none-inferiority, confirmatory design |
Treatment Group: Application of the investigational medical device (SkinPlus-HYAL Implant Lidocaine) Control Group: Application of the comparator device (RESTYLANE Lidocaine) |
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