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Population: Number of subject 100 |
\* In this investigation, the same subject receives both test and control treatments, one on each side of the nasolabial folds (matched pairs design). conditions: Nasal Disease conditions: Nasal Surgery studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription:... |
<|newrecord|> nctId: NCT06305507 id: 30923-N briefTitle: Differents Laser Applications on Plantar Fasciitis overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-06 date: 2024-07 date: 2024-03-12 date: 2024-03-13 name: University of Seville class: OTHER briefSummary: The objective of this randomized controlled cli... |
The main questions it seeks to answer are: |
* What is the comparative effectiveness between low-level laser therapy in local spot mode and sweep mode in reducing pain in patients with plantar fasciitis? |
* What are the optimal therapeutic parameters (session duration, frequency and power) for LLLT in both modes, maximizing pain reduction in patients with plantar fasciitis? |
Participants in this study will perform the following tasks: |
* Undergo low-level laser therapy sessions in local spot mode or sweep mode. |
* Comply with the instructions on the duration and frequency of the sessions. |
* Record the pain levels experienced before and after each session. |
The investigators will compare the group undergoing local spot mode low-level laser therapy with the group undergoing sweeping mode low-level laser therapy to evaluate whether there are significant differences in pain reduction effects. conditions: Fasciitis, Plantar studyType: OBSERVATIONAL observationalModel: COHORT ... |
<|newrecord|> nctId: NCT06305494 id: HE671008 briefTitle: Genitourinary Syndrome of Menopause in Thai Gynecologic Cancer Survivors overallStatus: RECRUITING date: 2024-03-14 date: 2024-12 date: 2024-12 date: 2024-03-12 date: 2024-04-25 name: Khon Kaen University class: OTHER briefSummary: Women often face common cancer... |
Treating these cancers often involves surgeries that might include removing ovaries or using pelvic radiation. This can trigger menopause in younger women, causing problems like vaginal dryness, itching, and urinary issues. |
Women who've gone through menopause often deal with these symptoms, affecting their daily lives, confidence, and intimate relationships. Though treatments are available, lack of awareness, embarrassment, and not discussing these issues with doctors can make managing them difficult. |
The main treatment for these symptoms is using vaginal estrogen, but it might not be suitable for some cancer survivors. Non-hormonal options like lubricants and moisturizers are alternatives. This study in Thailand aiming to explore how common these issues are among gynecological cancer survivors, their feelings about... |
<|newrecord|> nctId: NCT06305481 id: OPT1099 briefTitle: Glaucoma Evaluation With the P200TE overallStatus: RECRUITING date: 2024-02-13 date: 2024-09-30 date: 2024-09-30 date: 2024-03-12 date: 2024-03-12 name: Optos, PLC class: INDUSTRY briefSummary: Images captured on the P200TE device on glaucoma patients conditions:... |
<|newrecord|> nctId: NCT06305468 id: APHP240055 briefTitle: Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis acronym: TOXIC overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-04-01 date: 2026-04-01 date: 2024-03-12 date: 2024-03-12 name: Assistan... |
This study should make it possible to evaluate the impact of different anti-infective treatment regimens and to highlight clinical-biological and prognostic differences depending on the type of underlying immunosuppression. conditions: Toxoplasmosis studyType: OBSERVATIONAL observationalModel: OTHER timePerspective: RE... |
<|newrecord|> nctId: NCT06305455 id: HSD135 briefTitle: Resistance Profile of Escherichia Coli in Infections of Community Origin: The Importance of Antimicrobial Stewardship overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-07 date: 2024-10 date: 2024-03-12 date: 2024-03-12 name: José Raimundo Araujo de Azeved... |
<|newrecord|> nctId: NCT06305442 id: PR-24031 briefTitle: Microbiota Directed Food for Children With Moderate Acute Malnutrition overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2025-10-31 date: 2026-02-28 date: 2024-03-12 date: 2024-04-24 name: International Centre for Diarrhoeal Disease Research, Bangladesh c... |
<|newrecord|> nctId: NCT06305429 id: HABITE briefTitle: Encouraging Positive Parenting Habits acronym: HABITE overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-07 date: 2024-09 date: 2024-03-12 date: 2024-04-02 name: D'Or Institute for Research and Education class: OTHER name: Okinawa Institute of Science and ... |
<|newrecord|> nctId: NCT06305416 id: 2023/CT/01 briefTitle: A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema overallStatus: RECRUITING date: 2024-03-20 date: 2025-02 date: 2025-04 date: 2024-03-12 date: 2024-03-13 name: Incepta Pharmaceuticals Ltd class: IND... |
Diabetic macular edema (DME) is the most common cause of visual reduction in patients with Diabetes Mellitus. The prevalence of DME globally is around 6.8 %. Diabetic Retinopathy (DR) is the most common microvascular complication of diabetes and the leading cause of blindness worldwide. DME is a complication of diabeti... |
The use of therapeutic monoclonal antibodies has revolutionized in the treatment of many diseases. In recent years, millions of patients have been successfully treated with these biological agents. Ranibizumab is one such therapeutic monoclonal antibody for intraocular use. Ranibizumab is a humanized, recombinant, immu... |
<|newrecord|> nctId: NCT06305403 id: VEXUS1 briefTitle: VEXUS and NGAL in the Diagnosis and Prognosis of Sepsis-associated Acute Kidney Injury overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-03-18 date: 2025-05-18 date: 2024-03-12 date: 2024-04-23 name: Inonu University class: OTHER briefSummary: In this ... |
To determine whether patients develop AKI during the first five days of ICU admission, creatinine and urine output will be monitored daily for the first five days of ICU admission according to KDIGO criteria. Clinical diagnosis and treatment of AKI will be made according to KDIGO. |
According to KDIGO, patients will be divided into two groups: those who develop AKI and those who do not. |
By comparing plasma NGAL and VEXUS scores between groups, the sensitivity and specificity of the VEXUS score in determining AKI will be determined. conditions: Sepsis conditions: Acute Kidney Injury studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 100 type: ESTIMATED name: serum c... |
<|newrecord|> nctId: NCT06305390 id: 2022-003905-31 briefTitle: Fully Hybrid 18F-PSMA PET/MRI as One-stop Approach for the Diagnosis of Clinically Significant Prostate Cancer. acronym: RF2021-1237227 overallStatus: RECRUITING date: 2023-12-04 date: 2024-07 date: 2025-07 date: 2024-03-12 date: 2024-04-12 name: IRCCS San... |
Our main hypothesis is that adding 18F-PSMA PET to mpMRI prior to biopsy, will reduce the number of false negative findings, while at the same time, allowing also to reduce the number of unnecessary prostate biopsies in patients with low-risk, clinically indolent PCa. conditions: Clinical Suspicion of Prostate Cancer s... |
<|newrecord|> nctId: NCT06305377 id: DESPED-T1 study briefTitle: Achieving Rapid, Safe and Sustained Glucose Control in Adolescents With Suboptimally Controlled Type 1 Diabetes Using Advanced Hybrid Closed Loop Systems overallStatus: NOT_YET_RECRUITING date: 2024-03-11 date: 2024-03-30 date: 2024-03-30 date: 2024-03-12... |
<|newrecord|> nctId: NCT06305364 id: CL-1001 briefTitle: Predicting Adenomatous Polyps in the Colon Using Images of a Human Tongue overallStatus: RECRUITING date: 2023-08-01 date: 2024-12-01 date: 2024-12-01 date: 2024-03-12 date: 2024-03-20 name: Jubaan Ltd. class: INDUSTRY briefSummary: This is a prospective, multice... |
<|newrecord|> nctId: NCT06305351 id: K-757 P008 briefTitle: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes overallStatus: RECRUITING date: 2023-12-07 date: 2024-07 date: 2024-07 date: 2024-03-12 date: 2024-03-12 n... |
<|newrecord|> nctId: NCT06305338 id: KUK-Ophthalmology-009 briefTitle: Predicting Intraocular Lens Tilt Using OCT Measurements and Partial Least Squares Regression Modelling acronym: Tilt overallStatus: COMPLETED date: 2022-04-12 date: 2023-04-01 date: 2023-04-26 date: 2024-03-12 date: 2024-03-12 name: Johannes Kepler ... |
Various methods to measure IOL misalignments have been described. Studies assessing the IOL position have used subjective grading methods at the slit lamp examination or a Scheimpflug camera to assess IOL decentration and tilt. The subjective grading at the slitlamp may display considerable variability between examiner... |
The most recently developed method for tilt quantification is the use of optical coherence tomography. This method has several advantages compared to the previous methods: OCT based devices are available in most clinics, the resolution of modern OCT devices is high, and the measurements are reproducible. |
Aim of this study is to measure tilt with two modern OCT based devices and one Scheimpflug camera and to predict the post-operative tilt using partial least squares regression. This method was developed by Wold and introduced to ophthalmology previously. conditions: Intraocular Lens conditions: Cataract studyType: OBSE... |
<|newrecord|> nctId: NCT06305325 id: 35957 briefTitle: Coparenting Intervention to Prevent Postpartum Depression overallStatus: COMPLETED date: 2018-09-23 date: 2019-11-22 date: 2020-02-22 date: 2024-03-12 date: 2024-03-12 name: Brock University class: OTHER name: University of Toronto briefSummary: The goal of this pi... |
<|newrecord|> nctId: NCT06305312 id: HCI166685 id: 1R01CA282409-01 type: NIH link: https://reporter.nih.gov/quickSearch/1R01CA282409-01 briefTitle: Community Services Navigation to Advance Health Equity in Breast Cancer Screening acronym: B-SINCERE overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2028-09 date: 202... |
<|newrecord|> nctId: NCT06305299 id: LCCC2152-ATL briefTitle: Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2026-03 date: 2026-03 date: 2024-03-12 date: 2024-04-23 name: UNC Lineberger Comprehensive Cancer Center class: OTHER briefSum... |
There are two parts to this study. In part 1, approximately blood will be collected from subjects to prepare the iC9.CAR.B7-H3 T cells. The study team will collect disease-fighting T cells from the blood and modify them to prepare the iC9.CAR.B7-H3 T cells. In part 2, the iC9.CAR.B7-H3 T cells will be given to eligible... |
<|newrecord|> nctId: NCT06305286 id: IRB23-1367 briefTitle: Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D) overallStatus: RECRUITING date: 2024-03-04 date: 2029-03 date: 20... |
<|newrecord|> nctId: NCT06305273 id: 23-0150-A briefTitle: Effectiveness of Two Different Body Positions During Facemask Ventilation in Obese Patients overallStatus: NOT_YET_RECRUITING date: 2024-03-25 date: 2025-03-01 date: 2025-03-01 date: 2024-03-12 date: 2024-03-20 name: Mount Sinai Hospital, Canada class: OTHER br... |
There is some evidence in the research literature to suggest that when the patient is positioned in a way that helps their airway, like using a device to lift their head and torso 25 degrees , it might help the process of getting enough oxygen work better. The study aims to determine if patients with high BMI can breat... |
<|newrecord|> nctId: NCT06305260 id: STUDY00000324 briefTitle: LOTUS Trial: Lumbar Ultrasound in Obstetric Patients With BMI > 40 acronym: LOTUS overallStatus: ENROLLING_BY_INVITATION date: 2023-11-01 date: 2024-12-30 date: 2024-12-30 date: 2024-03-12 date: 2024-03-20 name: MetroHealth Medical Center class: OTHER brief... |
* Is a pre-procedural lumbar ultrasound superior to traditional palpation in terms of total number of epidural needle redirections during epidural placement? |
* Is there no difference in time to epidural loss between pre-procedural lumbar ultrasound and traditional palpation during epidural placement? Participants will be randomized to either a pre-procedural lumbar ultrasound or traditional palpation at the time of epidural placement. conditions: Obesity, Morbid conditions:... |
<|newrecord|> nctId: NCT06305247 id: CLIN-01194-450 id: 2023-506228-10-00 type: OTHER domain: Ipsen briefTitle: A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours overallStatus: RECRUITING date: 2024-04-03 date: 2028-03-20 date: 2028-03-20 date: 2024-03-12 date: 2024-04-19 name: Ip... |
The participants in this study will have advanced solid tumours. 'Advanced solid tumours' refers to cancers that can occur in several places, including cancers in organs or tissues that have spread from their original site to nearby tissues or other parts of the body. |
In this study, all participants will receive the study drug, which will be taken by mouth (orally). conditions: Melanoma conditions: Head and Neck Squamous Cell Carcinoma conditions: Pancreatic Ductal Adenocarcinoma conditions: Colorectal Cancer conditions: Solid Tumor studyType: INTERVENTIONAL phases: PHASE1 phases: P... |
Phase IIa (cohort expansion) is an open label randomised study. primaryPurpose: TREATMENT masking: NONE count: 220 type: ESTIMATED name: IPN01194 name: IPN01194 measure: Phase 1: Percentage of participants with dose limiting toxicity (DLT) measure: Phase 1: Percentage of participants experiencing Treatment-Emergent Adv... |
<|newrecord|> nctId: NCT06305234 id: 165-503 briefTitle: A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade) overallStatus: RECRUITING date: 2024-01-20 date: 2033-11-18 date: 2033-11-18 date: 2024-03-12 date: 2024-03-12 name: BioMarin Pharmaceutical class: IN... |
<|newrecord|> nctId: NCT06305221 id: opioid-free analgesia briefTitle: Effect of Opioid-free Analgesia and Anesthesia on the Quality of Postoperative Recovery and Nausea Vomit in Patients Receiving Laparoscopic Sleeve Gastrectomy overallStatus: RECRUITING date: 2024-03-09 date: 2025-03-31 date: 2025-03-31 date: 2024-03... |
<|newrecord|> nctId: NCT06305208 id: CCLR-23-018 briefTitle: A UK Registry for Metabolic and Bariatric Endoscopic Interventions acronym: UK-ENDOMAB overallStatus: RECRUITING date: 2024-02-01 date: 2034-02-01 date: 2039-02-01 date: 2024-03-12 date: 2024-03-15 name: Cleveland Clinic London class: OTHER briefSummary: In t... |
<|newrecord|> nctId: NCT06305195 id: 0107766 briefTitle: Potential Correlation Between Heart Rate Variability With Cardiovascular Risk at Different Stages of Metabolic Syndrome overallStatus: RECRUITING date: 2023-08-23 date: 2024-09-01 date: 2026-10-21 date: 2024-03-12 date: 2024-03-12 name: Alexandria University clas... |
Heart rate variability will be compared for some antidiabetic drugs used in different stages of metabolic diseases and correlated to different metabolic and inflammatory mediators. conditions: Diabetes Mellitus studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 155 type: ESTIMAT... |
<|newrecord|> nctId: NCT06305182 id: BASEC 2022-01328 briefTitle: Metreleptin in Anorexia Nervosa acronym: METRAN overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2026-02-01 date: 2026-02-01 date: 2024-03-12 date: 2024-03-15 name: Gabriella Milos class: OTHER briefSummary: The treatment of anorexia nervosa ofte... |
<|newrecord|> nctId: NCT06305169 id: 1.4 briefTitle: Measuring the Negative Predictive Value and Specificity of Serum Biomarkers in Gastric Cancer overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-06-01 date: 2024-07-01 date: 2024-03-12 date: 2024-03-12 name: Sandwell & West Birmingham Hospitals NHS Trust c... |
The difficulty with diagnosing patients with gastric cancer is that a lot of patients will suffer from heartburn and pain around the stomach, but very few of those will have gastric cancer. This makes it difficult for GPs to know who to refer for further testing as the current cancer referral criteria are very broad. |
To reduce the need for invasive diagnostic methods such as endoscopy where a flexible tube with camera is inserted into the gullet and stomach via the mouth, a commercially available blood test (GastroPanel ®) designed to measure the levels of certain key stomach hormones to detect atrophic gastritis has been developed... |
A real word study is needed assess the performance of this blood test in a group of patients referred via an urgent cancer pathway for endoscopy in the UK. Scoring systems have been created to help us triage referrals to endoscopy in those with difficulty swallowing, but no similar score is available for those presenti... |
<|newrecord|> nctId: NCT06305156 id: CT_BMD_1 briefTitle: Protocol Optimization in CT for the Quantification of BMD overallStatus: RECRUITING date: 2024-03-13 date: 2025-03 date: 2025-03 date: 2024-03-12 date: 2024-03-20 name: Hatem Alkadhi class: OTHER briefSummary: Bone mineral density is an important measurement to ... |
The goal of this clinical trial is to compare bone mineral density measurements in CT examinations and DXA scans. The main question it aims to answer is: |
* How good is the measurement of bone mineral density in the new photon-counting CT in comparison to DXA |
* How can we optimize the CT scan for bone mineral density |
Participants will undergo: |
* Clinically indicated CT scan on day of inclusion |
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