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The primary objective of this study is to assess the feasibility of conducting a large, randomized trial with regards to timely recruitment, study drug administration, protocol adherence, and overall retention in patients undergoing total joint arthroplasty. |
Secondarily, the investigators aim to obtain preliminary estimates of group-specific outcome means and variances for primary and secondary outcomes of a larger future trial. conditions: Hyperglycemia studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription... |
<|newrecord|> nctId: NCT06280261 id: GO20/296 briefTitle: The Struggle That Is Phenylketonuria : What Do The Patients and Caregivers Suffer From overallStatus: COMPLETED date: 2020-05-27 date: 2020-09-01 date: 2020-09-01 date: 2024-02-28 date: 2024-02-28 name: Hacettepe University class: OTHER briefSummary: Objective: ... |
<|newrecord|> nctId: NCT06280248 id: EUS in pancreatic fluid briefTitle: EUS Guided Drainage of Post Pancreatitis Pancreatic Fluid Collection overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-03 date: 2026-06 date: 2024-02-28 date: 2024-02-28 name: Assiut University class: OTHER briefSummary: The number as wel... |
* Assess the technical success rates, clinical success rates and potential complications of the different techniques for the best drainage of PFCs as regard type, caliber and number of plastic stents and ideal timing for stent removal. |
* Compare between early vs late intervention for complete endoscopic necrosectomy of WOPN as regard technical success rates, clinical success rates, potential complications and number of sessions needed. conditions: Pancreas Pseudocyst studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP ... |
<|newrecord|> nctId: NCT06280235 id: 1447-0005 id: U1111-1297-3126 type: REGISTRY domain: WHO International Clinical Trials Registry Platform (ICTRP) id: 2023-507942-10-00 type: REGISTRY domain: CTIS briefTitle: A Study to Test Different Doses of BI 1569912 in People With Depression Who Take Anti-depressive Medicine ov... |
Participants continue their standard therapy throughout the study. |
Participants are put into 4 groups by chance. 3 of the 4 groups take different doses of BI 1569912. 1 group takes placebo. Placebo tablets looks like BI 1569912 but do not contain any medicine. Participants take the tablets once a day for 6 weeks. |
Participants are in the study for about 2 to 4 and a half months. During this time, they visit the study site at least 6 times. At the visits, doctors ask participants about their symptoms. |
The participants answer questions about their depression symptoms. The results are compared between the groups. The doctors also regularly check the general health of participants. conditions: Depressive Disorder, Major studyType: INTERVENTIONAL phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL primaryP... |
<|newrecord|> nctId: NCT06280222 id: VR FOR ANXIETY-HMO-CTIL briefTitle: The Effectiveness of Virtual Reality on Anxiety Reduction in Women Undergoing Elective Egg Cryopreservation. acronym: VRFORANXIETY overallStatus: RECRUITING date: 2023-11-15 date: 2024-11-15 date: 2025-02-01 date: 2024-02-28 date: 2024-02-28 name:... |
<|newrecord|> nctId: NCT06280209 id: 351-201 id: 2023-506737-30-00 type: OTHER domain: EU CT briefTitle: A Phase 1/2 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMN 351 in Participants With Duchenne Muscular Dystrophy overallStatus: RECRUITING date: 2024-01-03 date: 2025-12 date:... |
<|newrecord|> nctId: NCT06280196 id: BAT-3306-002-CR briefTitle: A Study to Evaluate PK, Efficacy, and Safety of BAT3306 Plus Chemo and Compare With Keytruda®(EU/US) in Participants With IV nqNSCLC overallStatus: NOT_YET_RECRUITING date: 2024-08-15 date: 2027-07-30 date: 2028-10-30 date: 2024-02-28 date: 2024-03-25 nam... |
<|newrecord|> nctId: NCT06280183 id: 323132 briefTitle: Functional Inspiratory Muscle Training in Obese Individuals overallStatus: NOT_YET_RECRUITING date: 2024-02-28 date: 2025-06-30 date: 2025-06-30 date: 2024-02-28 date: 2024-02-28 name: Biruni University class: OTHER name: Istanbul Galata University briefSummary: I... |
This study aims to investigate the effects of functional inspiratory muscle training on body composition, cardiometabolic markers, functional capacity, respiratory function, respiratory muscle strength, and respiratory muscle performance in obese individuals. conditions: Obesity studyType: INTERVENTIONAL phases: NA all... |
<|newrecord|> nctId: NCT06280170 id: ST11480 briefTitle: AI to Support Mental Health Case Management Providers overallStatus: ENROLLING_BY_INVITATION date: 2024-02-19 date: 2025-06-30 date: 2025-12-31 date: 2024-02-28 date: 2024-02-28 name: Eleos Health class: INDUSTRY name: Centerstone Research Institute briefSummary:... |
1. Is the AI platform acceptable and feasible for case managers? |
2. Does the AI platform improve providers' productivity and reported interventions? Participants will be approximately 30 case managers and their 250 adult clients receiving case management services. Researchers will compare the provider productivity and work satisfaction prior to the implementation of the AI platform ... |
<|newrecord|> nctId: NCT06280157 id: MVX0007 id: 332126 type: OTHER domain: IRAS briefTitle: A Follow up Study of Group B Streptococcus Vaccine (GBS-NN/NN2 Vaccine) in Healthy Volunteers overallStatus: ENROLLING_BY_INVITATION date: 2024-01-18 date: 2028-01 date: 2028-01 date: 2024-02-28 date: 2024-02-28 name: Minervax ... |
Participants who had received a primary course of GBS-NN/NN2 in Study MVX0002 and/or MVX0003 will be invited to return to have a single yearly blood sample of approximately 10 mL collected 2 to 5 years after the completion of the previous vaccination. conditions: Group B Streptococcus Infection studyType: OBSERVATIONAL... |
<|newrecord|> nctId: NCT06280144 id: PF20230428 briefTitle: Post-marketing Study of Lyophilized Nasal Spray Live Attenuated Influenza Vaccine overallStatus: RECRUITING date: 2023-09-22 date: 2024-06-30 date: 2024-10-30 date: 2024-02-28 date: 2024-02-28 name: Changchun BCHT Biotechnology Co. class: INDUSTRY name: Hu Bei... |
To evaluate the protective effect of novel coronavirus after 14 days of inoculation with the live attenuated influenza vaccine. conditions: Influenza Prevention studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: PREVENTION masking: TRIPLE whoMasked: PARTICIPANT w... |
<|newrecord|> nctId: NCT06280131 id: multiple sclerosis and pulse briefTitle: The Efficacy of Pulse Therapy in Acute Relapse in Multiple Sclerosis Patients: overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2025-03-01 date: 2025-04-01 date: 2024-02-28 date: 2024-02-28 name: Assiut University class: OTHER briefSu... |
<|newrecord|> nctId: NCT06280118 id: EFCPR008 briefTitle: The Effect of Fatigue on CPR overallStatus: COMPLETED date: 2023-04-20 date: 2023-06-20 date: 2023-10-25 date: 2024-02-28 date: 2024-02-28 name: Artvin Coruh University class: OTHER briefSummary: Background: This study, in contrast to the previous studies, gener... |
Methods: The study was designed as a randomized controlled trial. The sample, consisting of 84 paramedic students, was randomly assigned as 42 control and 42 experimental groups. Fatigue was created in the participants by rehearsing the process of removing and transporting earthquake victims from the rubble through the... |
<|newrecord|> nctId: NCT06280105 id: 2023_148_01 briefTitle: A Trial of Cadonilimab Plus Regorafenib in Patients With Hepatocellular Carcinoma Who Failed Camrelizumab Combined With Apatinib overallStatus: NOT_YET_RECRUITING date: 2024-03-31 date: 2026-03-31 date: 2027-03-31 date: 2024-02-28 date: 2024-02-28 name: Meng ... |
<|newrecord|> nctId: NCT06280092 id: 23-009133 briefTitle: Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surgery overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-03 date: 2025-03 date: 2024-02-28 date: 2024-04-08 name: Sanjeet S. Grewal class: OTHER br... |
Subjects will be screened at our outpatient clinic and interested qualified subjects will be consented and offered participation in this trial. Once consent has been obtained, patients will undergo a standard preoperative evaluation which includes baseline laboratory values and a high-definition MRI. Patients will then... |
Patients will be followed in the outpatient setting for up to a year after therapy application. |
Surgical, clinical, and radiographic data will be obtained during these visits conditions: Epilepsy studyType: INTERVENTIONAL phases: EARLY_PHASE1 allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: A single dose of 5x10\^6 AMSCs will be resuspended in 1ml of LRS and infused via intraparenchyma... |
<|newrecord|> nctId: NCT06280079 id: LIPCAL-ALS II 1.1 briefTitle: Ultra-high-caloric, Fatty Diet in ALS acronym: LIPCAL-ALS II overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2027-05-01 date: 2027-05-01 date: 2024-02-28 date: 2024-03-01 name: University of Ulm class: OTHER briefSummary: This study aims at eva... |
<|newrecord|> nctId: NCT06280066 id: 2023/607 briefTitle: An Intervention-Based Approach to Strengthen the Psychological Health of Children With Cystic Fibrosis and Their Mothers overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-06 date: 2024-09 date: 2024-02-28 date: 2024-04-17 name: Kirsehir Ahi Evran Univer... |
<|newrecord|> nctId: NCT06280053 id: 103-3024A3 briefTitle: HealiAid in the Treatment of Different Wounds overallStatus: COMPLETED date: 2016-03-02 date: 2018-04-11 date: 2018-10-26 date: 2024-02-28 date: 2024-02-28 name: Maxigen Biotech Inc. class: INDUSTRY briefSummary: The goal of this open-label, post-market clinic... |
The main questions it aims to answer are: |
1. The wound healing which was defined as the percentage of area change. |
2. The duration of wound healing. |
3. The granulation tissue growth of the wound. |
4. The wound exudate. |
5. Safety Indicators of which incidences after treatment. |
HealiAid will be applied to eligible subjects who will later be followed up for 12 weeks. conditions: Venous Ulcers conditions: Bedsores conditions: Diabetic Foot Wound conditions: Burn Wound studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: The patients' ... |
<|newrecord|> nctId: NCT06280040 id: UM Longitudinal 1942/2022 briefTitle: Longitudinal Follow-Up of Patients Treated With Hypofractionated Stereotactic Photon Radiotherapy Due to Uveal Melanoma overallStatus: RECRUITING date: 2023-11-23 date: 2025-06-30 date: 2025-06-30 date: 2024-02-28 date: 2024-03-06 name: Medical ... |
<|newrecord|> nctId: NCT06280027 id: MUDHF_BK1 briefTitle: Effect of Midline Discrepancy and Crown Width Disporportion on Esthetics overallStatus: COMPLETED date: 2023-06-05 date: 2023-06-12 date: 2023-12-22 date: 2024-02-28 date: 2024-02-28 name: Marmara University class: OTHER briefSummary: In the web-based cross-sec... |
A frontal view full-face portrait image of a 25-year-old female was selected as a model for the study, with a smile exhibiting good dental alignment, a quite good midline position, and tooth size symmetry. |
The original image was digitally modified by a single restorative instructor using Photoshop CC (Adobe, USA) software program. The modifications were divided into three parts. The first part was the generation of midline discrepancy at different levels. The midline was digitally moved to the right side of the patient 1... |
The second part was the generation of individual crown width disproportions. Accordingly, the mesiodistal width of the left central, lateral, and canine was digitally decreased one by one, gradually, while the width of the symmetrical teeth on the right side was simultaneously increased. |
The third part was the generation of distributed crown width disproportions. Accordingly, the total mesiodistal width of the left central, lateral, and canine was equally decreased, gradually, while the total width of the symmetrical teeth on the right side was simultaneously increased. |
In total, 15 images were displayed in random order to the participants including the original image. An online survey was generated to quantitatively evaluate the level of esthetic perception. Subsequently, the participants were asked to evaluate the level of smile esthetics of the presented random images, without bein... |
<|newrecord|> nctId: NCT06280014 id: YYU-09/15.12.2021 briefTitle: Evaluation of the Effects of Mefenamic Acid and Dexketoprofen on Postoperative Wisdom Dental Surgery overallStatus: COMPLETED date: 2022-01-20 date: 2022-02-20 date: 2023-09-25 date: 2024-02-28 date: 2024-02-28 name: Yuzuncu Yıl University class: OTHER ... |
<|newrecord|> nctId: NCT06280001 id: 2023YFC2308802-04 briefTitle: A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of HIV/AIDS Complicated With Infection overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-11 date: 2026-11 date: 2024-02-28 date: 2024-03-04 name: Zhejiang University class... |
* Describe the populations and characteristics of pathogenic microorganisms involved in HIV co-infection, map the spatial and temporal changes in the infection system of pathogenic microorganisms, and evaluate their impact on disease regression. |
* Explore the mechanism of interaction between pathogenic microorganisms and host autoimmune deficiencies. |
* Discover early warning and predictive markers and immunological indicators of pathogenic microorganisms, and explore new technologies and programs to reduce the mortality rate of infection. conditions: Acquired Immunodeficiency Syndrome conditions: HIV Infections studyType: OBSERVATIONAL observationalModel: COHORT ti... |
<|newrecord|> nctId: NCT06279988 id: K24 briefTitle: BRING-UP 3 Heart Failure acronym: BRING-UP3HF overallStatus: RECRUITING date: 2023-09-15 date: 2026-06-30 date: 2026-07-30 date: 2024-02-28 date: 2024-02-28 name: Heart Care Foundation class: OTHER briefSummary: The aim of this observational study is to assess the le... |
<|newrecord|> nctId: NCT06279975 id: Req-2023-01275; am23Sutter2 briefTitle: Pupillometric Evaluation in Patients Declared Brain Dead - a Prospective Quality Control Study acronym: INSPECT overallStatus: RECRUITING date: 2023-12-18 date: 2029-12 date: 2030-12 date: 2024-02-28 date: 2024-02-28 name: University Hospital,... |
<|newrecord|> nctId: NCT06279962 id: 2000034620 briefTitle: Survey Experiment to Estimate Level of Mental Illness Stigma Based on Condition and Gender overallStatus: COMPLETED date: 2023-06-15 date: 2023-09-15 date: 2023-09-15 date: 2024-02-28 date: 2024-02-28 name: Yale University class: OTHER name: Empower Through He... |
<|newrecord|> nctId: NCT06279949 id: 2000036999 id: 1K01MH136929-01 type: OTHER domain: NIMH *ID not yet added briefTitle: Confidential Care and Adolescent HIV Testing overallStatus: NOT_YET_RECRUITING date: 2026-04 date: 2027-10 date: 2027-10 date: 2024-02-28 date: 2024-02-28 name: Yale University class: OTHER name: N... |
<|newrecord|> nctId: NCT06279936 id: B3002021000171 briefTitle: Neurobiological Underpinnings of Neuropsychological Consequences in Long COVID acronym: Cov-N-Psy overallStatus: ACTIVE_NOT_RECRUITING date: 2021-11-01 date: 2023-12-31 date: 2024-12-31 date: 2024-02-28 date: 2024-02-28 name: Universiteit Antwerpen class: ... |
To describe the standardized evaluation of the psychological and cognitive function of long COVID patients and their evolution, to compare immunological and HPA-axis related biomarkers between long COVID patients and healthy controls, to explore cross-sectional and longitudinal associations between immunological measur... |
Study design: |
Cov-N-Psy is a longitudinal observational study. Three groups will be included from 2021 until 2023: long COVID patients with neuropsychological complaints (P), COVID-survivors without persistent complaints (Ca) and healthy volunteers without a history of COVID-19 (Cb). The total sample size is estimated on 130. Four v... |
The study is organized in three work packages (WP). WP1 includes a blood withdrawal and psychometric questionnaires and is part of every visit. WP2 includes cortisol measurement in saliva and takes place on the baseline visit for every participant and on the third visit for patients. Finally, WP3 includes a neurocognit... |
<|newrecord|> nctId: NCT06279923 id: TXB2023023 briefTitle: CD19-BAFF CAR-T Cells Therapy for Patients With Autoimmune Diseases overallStatus: RECRUITING date: 2024-04-15 date: 2027-02-01 date: 2027-02-01 date: 2024-02-28 date: 2024-04-09 name: Zhejiang University class: OTHER name: Shanghai YaKe Biotechnology Ltd. bri... |
<|newrecord|> nctId: NCT06279910 id: 2021 36 (EOm) briefTitle: Calcifediol in the Treatment of SARS-CoV-2 Disease (COVID-19). acronym: COVIDIOL overallStatus: RECRUITING date: 2024-02-21 date: 2024-03-21 date: 2024-04-25 date: 2024-02-28 date: 2024-02-28 name: Complejo Hospitalario Universitario de Albacete class: OTHE... |
<|newrecord|> nctId: NCT06279897 id: 2023-068 briefTitle: LBNP Tolerance With Skin Warming After Exercise Cold Stress overallStatus: RECRUITING date: 2022-01-24 date: 2025-09-30 date: 2025-09-30 date: 2024-02-28 date: 2024-02-28 name: University of Colorado, Colorado Springs class: OTHER briefSummary: Assess the effect... |
<|newrecord|> nctId: NCT06279884 id: 2023YFC2308802-03 briefTitle: A Cohort Study on the Pathogen Spectrum of Liver Transplant Recipients Complicated With Infection overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-11 date: 2026-11 date: 2024-02-28 date: 2024-03-04 name: Zhejiang University class: OTHER name: ... |
* Characterize the distribution of pathogenic bacteria infecting liver transplant recipients. |
* Establish a monitoring and early warning system for secondary infections. conditions: Liver Transplantation conditions: Transplant Recipients studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 1000 type: ESTIMATED measure: Secondary Infections in liver transplant recipients at 4 w... |
<|newrecord|> nctId: NCT06279871 id: ARCT-2303-01 briefTitle: Immunogenicity and Safety Study of Self-amplifying mRNA COVID-19 Vaccine Administered With Influenza Vaccines in Adults overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2024-10 date: 2024-12 date: 2024-02-28 date: 2024-02-28 name: Arcturus Therapeutics,... |
<|newrecord|> nctId: NCT06279858 id: 1-2024 briefTitle: Probiotic Intervention for Microbiome Modifications and Clinical Improvements in Fragile X Syndrome overallStatus: RECRUITING date: 2024-01-01 date: 2024-12-31 date: 2024-12-31 date: 2024-02-28 date: 2024-02-28 name: Specila hospital for cerebral palsy and develop... |
This is open label trial without masking, where each participant receives probiotic for 3 months (12 weeks). It will be single group assignment. The study plans to enroll 15 participants with FXS, aged 3-18 years, both sexes, during 1-year period and complete all study-related activities by January 2025. During the 3-m... |
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