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<|newrecord|> nctId: NCT06279845 id: 2023YFC2308802-02 briefTitle: A Clinical Cohort Study on the Pathogen Spectrum of Hepatic Virus-caused Cirrhosis Complicated With Infection overallStatus: NOT_YET_RECRUITING date: 2024-03 date: 2026-11 date: 2026-11 date: 2024-02-28 date: 2024-03-04 name: Zhejiang University class: ... |
* Describe the populations and characteristics of pathogenic microorganisms responsible for co-infections in patients with hepatic virus-caused cirrhosis. |
* Map the spectrum of pathogenic microorganisms, and evaluate their impact on disease regression. conditions: Liver Cirrhosis studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 2000 type: ESTIMATED measure: Secondary infection in patients at 4 weeks measure: quick SEPSIS RELATED ORG... |
<|newrecord|> nctId: NCT06279832 id: 3994 briefTitle: Radiomics and Radiogenomics Models to Predict Molecular Integrated Risk Classes and Prognostic Factors in Endometrial Cancer. acronym: Romantic overallStatus: RECRUITING date: 2023-11-01 date: 2024-10-31 date: 2025-10-31 date: 2024-02-28 date: 2024-02-28 name: Fonda... |
These models would support clinicians in personalizing surgical and adjuvant treatment choice among the options considered by the international guidelines. conditions: Endometrial Cancer studyType: INTERVENTIONAL phases: NA allocation: NA interventionModel: SINGLE_GROUP interventionModelDescription: As far as the sampl... |
<|newrecord|> nctId: NCT06279819 id: 2024-008 briefTitle: Effectiveness of Gut Microbiota-targeted Dietary Intervention Among HIV-infected Patients overallStatus: NOT_YET_RECRUITING date: 2024-03-01 date: 2024-12-31 date: 2024-12-31 date: 2024-02-28 date: 2024-02-28 name: Fudan University class: OTHER briefSummary: The... |
* Explore the pivotal role of the gut-heart axis in the causal relationship between HIV infection and atherosclerotic cardiovascular disease. |
* Develop a targeted dietary intervention focusing on gut microbiota to prevent the borderline risk of atherosclerotic cardiovascular disease in HIV-infected patients. |
* Evaluate the effectiveness of the gut microbiota-targeted dietary intervention in reducing atherosclerotic cardiovascular disease risk among HIV-infected patients, altering gut microbiota composition, improving risk factors of atherosclerotic cardiovascular disease, and alleviating prodromal symptoms associated with ... |
Participants in the intervention group will receive the gut microbiota-targeted dietary intervention thrice weekly for 3 months, accompanied by bi-weekly health education videos for the same duration. Meanwhile, the control group will continue routine follow-up and health education practices. The intervention will span... |
<|newrecord|> nctId: NCT06279806 id: SerapAlkas briefTitle: The Effect of Mobile Health Application on Posttraumatic Growth in Women Diagnosed With Breast Cancer overallStatus: NOT_YET_RECRUITING date: 2024-02-28 date: 2024-06-30 date: 2024-10-30 date: 2024-02-28 date: 2024-02-28 name: Gazi University class: OTHER brie... |
<|newrecord|> nctId: NCT06279793 id: MODIFYCSX briefTitle: Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients. acronym: MODIFYCSX overallStatus: RECRUITING date: 2024-02-15 date: 2024-12-01 date: 2025-12-01 date: 2024-02-28 date: 2024-02-28 name: GCP-Service Internationa... |
In this prospective randomized controlled blinded multicenter trial, a total of 120 high-risk cardiac surgery patients will receive either standard of care + OMEGAVEN at 0.20 g/kg ideal body weight (IBW) versus placebo + standard of care. conditions: Cardiac Surgery conditions: High Risk Patients conditions: Intensive ... |
<|newrecord|> nctId: NCT06279780 id: PI18/00932 briefTitle: Gut Microbiota, Mitochondrial Function and Metabolic Health in Obesity overallStatus: ACTIVE_NOT_RECRUITING date: 2019-01-01 date: 2023-12-31 date: 2024-08-31 date: 2024-02-28 date: 2024-02-28 name: Celia Bañuls class: OTHER name: Instituto de Salud Carlos III... |
<|newrecord|> nctId: NCT06279767 id: 2022-SR-557 briefTitle: Efficacy and Safety of TMZ Plus 6-MP in the Patients With Recurrent Glioblastoma overallStatus: RECRUITING date: 2022-07-01 date: 2025-07-01 date: 2025-07-31 date: 2024-02-28 date: 2024-02-28 name: The First Affiliated Hospital with Nanjing Medical University... |
<|newrecord|> nctId: NCT06279754 id: ZLXGBXKYXM-031-01 briefTitle: Recombinant Human Endostatin Combined With Envafolimab and Synchronal Radiochemotherapy overallStatus: NOT_YET_RECRUITING date: 2024-02-18 date: 2024-06-18 date: 2025-12-18 date: 2024-02-28 date: 2024-02-28 name: The First Affiliated Hospital of Xinxian... |
<|newrecord|> nctId: NCT06279741 id: EVENEW id: 2022-500293-34 type: EUDRACT_NUMBER id: U1111-1291-0283 type: OTHER domain: Universal Trial Number briefTitle: Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants acronym: EVENEW overallStatus: RECRUITING date: 2023-12-28 date: 2027-01-31 ... |
Infants will be followed up to 2 years of corrected age (end of study). conditions: Bronchopulmonary Dysplasia studyType: INTERVENTIONAL phases: PHASE1 phases: PHASE2 allocation: RANDOMIZED interventionModel: PARALLEL interventionModelDescription: Phase 1 is an open-labelled, dose-escalated, and single-arm of EXOB-001.... |
<|newrecord|> nctId: NCT06279728 id: DS1062-0003-EAP-MA briefTitle: Medical Access Program for Datopotamab Deruxtecan in NSCLC Patients overallStatus: AVAILABLE date: 2024-02-28 date: 2024-04-08 name: Daiichi Sankyo class: INDUSTRY name: AstraZeneca briefSummary: The purpose of this Medical Access Program (also referre... |
<|newrecord|> nctId: NCT06279715 id: 3437 briefTitle: DFI and Aneuploidies overallStatus: ACTIVE_NOT_RECRUITING date: 2024-01-19 date: 2024-12-31 date: 2025-02-01 date: 2024-02-28 date: 2024-02-28 name: Clinique Ovo class: INDUSTRY briefSummary: IVF is the most commonly employed form of assisted reproductive technologi... |
Segmental aneuploidies are generated when a small piece of a chromosome is gained or lost during cell division, resulting in subchromosomal copy number (CN) changes. The frequency of segmental aneuploidies during the cleavage stage varies between studies, from as low as 3.9% to 15% and up to 70 % with no reported corre... |
<|newrecord|> nctId: NCT06279702 id: OCalisir briefTitle: Serious Game Simulation and Comics in School Students overallStatus: ACTIVE_NOT_RECRUITING date: 2023-07-19 date: 2025-07-19 date: 2025-07-19 date: 2024-02-28 date: 2024-02-28 name: TC Erciyes University class: OTHER briefSummary: The aim of the study is to dete... |
Hypotheses: |
H1: First aid training given through simulation applications affects the level of knowledge. |
H2: First aid training given through simulation applications affects the skill level. |
H3: First aid training given with simulation application affects motivation. |
H4: First aid training given with comics affects the level of knowledge. |
H5: First aid training given with comic books affects the skill level. |
H6: First aid training given with comics affects motivation. |
METHOD: The research will be conducted as a randomized controlled experimental study with a pre-test-post-test design with children studying in the 5th and 6th grades of schools in the central district of Aksaray. One group will be given first aid training for injuries prepared with serious games, the other group will ... |
<|newrecord|> nctId: NCT06279689 id: CJTCDZ2301 briefTitle: Echography Study_Anthropometric Measurements overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2024-06 date: 2024-06 date: 2024-02-28 date: 2024-02-28 name: Crossject class: INDUSTRY briefSummary: This is a multi-center, exploratory, estimation study in bo... |
In the healthy adult population, anatomical characteristics of one shoulder (deltoid) and one upper arm (biceps and triceps) will also be evaluated by ultrasound scan before and while applying a force similar to ZENEO® triggering force. |
Only ultrasound procedures will be performed using an investigational ultrasound system. All subjects will be asked to undergo 1 on site visit (Study Visit) during which the eligibility assessment and the ultrasound scans will be performed. conditions: Healthy Subjects studyType: INTERVENTIONAL phases: NA allocation: N... |
<|newrecord|> nctId: NCT06279676 id: SaFeGreff briefTitle: Improvement of Women's Health After Allogeneic Stem Cell Transplantation acronym: SaFeGreff overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2028-07 date: 2028-12 date: 2024-02-28 date: 2024-02-28 name: Ciusss de L'Est de l'Île de Montréal class: OTHER nam... |
<|newrecord|> nctId: NCT06279663 id: NSTE-ACS Multivessel Trial briefTitle: Management Tactics for Patients High Risk With Acute Coronary Syndrome Without ST Segment Elevation and Multivessel Coronary Artery Disease acronym: NSTE-ACSMT overallStatus: RECRUITING date: 2024-02-29 date: 2028-12-31 date: 2029-12-31 date: 2... |
<|newrecord|> nctId: NCT06279650 id: 2022-2741 briefTitle: Self-hypnosis Training for Chronic Pain Management overallStatus: RECRUITING date: 2024-02-01 date: 2024-06 date: 2024-12 date: 2024-02-28 date: 2024-02-28 name: Ciusss de L'Est de l'Île de Montréal class: OTHER briefSummary: Title: Self-hypnosis training in ch... |
The study design is a Randomized efficacy pilot study. The study focuses on patients practicing self-hypnosis within HMR groups. The study population is pain clinic patients. The sample size is 60 pain clinic patients. Study duration: February 2024 - December 2024. Center responsible for the study: Centre de Recherche ... |
Adverse events: none expected. conditions: Hypnosis, Chronic Pain Management studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: SUPPORTIVE_CARE masking: SINGLE whoMasked: PARTICIPANT count: 60 type: ESTIMATED name: Self-hypnosis name: Psycho-education and cognitive B... |
<|newrecord|> nctId: NCT06279637 id: PRO00046457 briefTitle: Joint Patient and Caregiver Intervention for Older African Americans With Type 2 Diabetes overallStatus: NOT_YET_RECRUITING date: 2024-03-04 date: 2026-07 date: 2026-07 date: 2024-02-28 date: 2024-02-28 name: Medical College of Wisconsin class: OTHER briefSum... |
The aims of the study are: |
Aim 1: To test the preliminary efficacy of home-based, joint patient and caregiver intervention (Joint Home-DM-BAT) on patient clinical outcomes (hemoglobin A1c, blood pressure, and LDL-Cholesterol). |
Aim 2: To test the preliminary efficacy of home-based, joint patient and caregiver intervention (Joint Home-DM-BAT) Joint Home DM-BAT on patient quality of life. |
Aim 3: To test the preliminary efficacy of home-based, joint patient and caregiver intervention (Joint Home-DM-BAT) on caregiver quality of life and caregiver burden. conditions: Type 2 Diabetes studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: HEALTH_SERVICES_RESEA... |
<|newrecord|> nctId: NCT06279624 id: NRCT9-4 briefTitle: Effectiveness of the PCV13 in Older Thai Adults overallStatus: NOT_YET_RECRUITING date: 2024-02 date: 2025-03 date: 2025-06 date: 2024-02-28 date: 2024-02-29 name: Mahidol University class: OTHER name: National Research Council of Thailand briefSummary: This is t... |
The goal of this observational study is to evaluate the effectiveness of the 13-valent pneumococcal conjugate vaccine (PCV13) in pneumococcal CAP in Thai adults aged ≥ 60 years with or without any medical conditions. |
The main questions it aims to answer is: |
• What are the effectiveness of PCV13 for preventing all typed, vaccine typed, or non-vaccine typed of pneumococcal CAP among Thai older adults? |
The investigators retrospectively collect cases and control who are diagnosed with CAP accordingly from January 2012 through October 2023. The investigators define case and control the same as prospective method, but all data were retrieved from archive database. |
-The investigators select a 1:2 matched control with criteria as follows; 10-year-interval of age, ward (the same patient care such as out or in-patient, or admitted in the same level ward). |
Participants will be |
* collated from hospital database regarding their CAP illnesses by pneumococcal and non-pneumococcal pneumonia condition. |
* explored their vaccine status by either vaccine book checking or hospital database. |
Researcher will compare the effectiveness of PCV13 to prevent all typed, vaccine typed and non-vaccine typed pneumococcal pneumonia. conditions: Community-acquired Pneumonia studyType: OBSERVATIONAL observationalModel: CASE_CONTROL timePerspective: OTHER count: 840 type: ESTIMATED measure: Vaccine effectiveness of PCV1... |
<|newrecord|> nctId: NCT06279611 id: LY007C1101 briefTitle: An Evaluation of LY007 Cell Injection for r/r B-NHL acronym: r/r B-NHL overallStatus: RECRUITING date: 2021-12-25 date: 2024-08-31 date: 2026-05-31 date: 2024-02-28 date: 2024-02-28 name: Shanghai Longyao Biotechnology Inc., Ltd. class: OTHER name: The First A... |
<|newrecord|> nctId: NCT06279598 id: UniversityGroningen briefTitle: PT-STRESS Study: Predicting Treatment Success and Dealing With Non-response in the Treatment of PTSD acronym: PT-STRESS overallStatus: RECRUITING date: 2024-01-01 date: 2031-05-20 date: 2032-08-31 date: 2024-02-28 date: 2024-02-28 name: University of ... |
Key questions: |
1. Which predictors of treatment success influence treatment outcome of patients with PTSD who receive the three psychotherapeutic treatments investigated in this study? |
2. Which specific moderators can be identified with regard to the different psychotherapies (Eye Movement Desensitization and Reprocessing -EMDR-; Prolonged Exposure -PE-; and Interpersonal Psychotherapy -IPT- in the second phase)? |
3. In patients with PTSD, does offering another proven effective form of trauma-focused psychotherapy (PE after EMDR, or EMDR after PE) improve symptoms following insufficient response to a first trauma-focused treatment? |
4. Is switching from a trauma-focused therapy to a non-trauma-focused treatment (IPT) a more effective strategy for dealing with non-response to a first proven effective psychotherapeutic treatment compared to switching to another trauma-focused therapy? |
5. Are there differences in treatment tolerance and differences in dropout rates between PE, EMDR and IPT? |
Secondary goals: |
* Investigating the extent to which therapist allegiance to a specific therapy method affects outcomes; |
* Investigating whether the quality of therapy implementation or the treatment integrity ('adherence/ competence') affects treatment outcomes; |
* Investigating how much the quality of the therapeutic alliance influences outcomes. |
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