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<|newrecord|> nctId: NCT06369597 id: Robot2024 briefTitle: A Randomized Controlled Trial of the Safety and Efficacy of Robotic Telesurgery Versus Laparoscopic Surgery overallStatus: NOT_YET_RECRUITING date: 2024-04-15 date: 2024-12-31 date: 2025-03-31 date: 2024-04-17 date: 2024-04-17 name: Sun Yat-sen University class... |
<|newrecord|> nctId: NCT06369584 id: PEPAD briefTitle: Prone Position During ECMO in Pediatric Patients With Severe ARDS acronym: PEPAD overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-07-01 date: 2024-04-17 date: 2024-04-17 name: Seventh Medical Center of PLA General Hospital class: OTHER... |
In 2018, the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) study group conducted a retrospective analysis and concluded that ECMO does not significantly improve survival rates for severe PARDS. However, this retrospective study mainly focused on data from North America, with significant ... |
ECMO can also serve as a salvage measure for severely ARDS children who have failed conventional mechanical ventilation treatment. When optimizing ventilator parameters (titrating positive end expiratory pressure (PEEP) levels, neuromuscular blockers, prone positioning), strict fluid management alone cannot maintain sa... |
<|newrecord|> nctId: NCT06369571 id: IRB00439268 briefTitle: Improving Cardiovascular Health Risks in Adults With Epilepsy on a Modified Atkins Diet overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2027-01 date: 2027-12 date: 2024-04-17 date: 2024-04-17 name: Johns Hopkins University class: OTHER name: American He... |
<|newrecord|> nctId: NCT06369558 id: BiruniUniversi briefTitle: Plyometric Exercise Training in Athletes With Chronic Low Back Pain overallStatus: COMPLETED date: 2024-01-01 date: 2024-04-04 date: 2024-04-04 date: 2024-04-17 date: 2024-04-17 name: Ugur Cavlak class: OTHER name: Biruni University briefSummary: The aim o... |
<|newrecord|> nctId: NCT06369545 id: BiruniUniver briefTitle: Chronic Pelvic Pain Syndrome in Males overallStatus: RECRUITING date: 2024-01-01 date: 2024-04-04 date: 2024-08-15 date: 2024-04-17 date: 2024-04-17 name: Biruni University class: OTHER briefSummary: The aim of this study is to evaluate the effectiveness of ... |
<|newrecord|> nctId: NCT06369532 id: ONZ-2023-0460 briefTitle: Combination of Neurostimulation and Psychotherapy to Stop Worrying overallStatus: RECRUITING date: 2024-03-06 date: 2026-02-20 date: 2027-02-20 date: 2024-04-17 date: 2024-04-17 name: University Hospital, Ghent class: OTHER briefSummary: This study aims to ... |
<|newrecord|> nctId: NCT06369519 id: 2023#17-23 briefTitle: Optimization of Management for Sporadic Bilateral Renal Cell Carcinoma overallStatus: COMPLETED date: 2000-01-01 date: 2020-12-31 date: 2020-12-31 date: 2024-04-17 date: 2024-04-17 name: Peking University First Hospital class: OTHER briefSummary: Sporadic bila... |
What are the factors influencing the prognosis of BRCC patients? What's the appropriate treatment for BRCC patients? |
Researchers will analysis the prognostic factors and compare the prognosis of BRCC patients receiving different treatments. conditions: Kidney Cancer studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: RETROSPECTIVE count: 3677 type: ACTUAL name: Surgery treatment or local tumor destruction. measure: O... |
<|newrecord|> nctId: NCT06369506 id: PYO.DIS.1904 Protocol ID:4467 briefTitle: Evaluation of Gingival Thickness Measurement at Different Anatomical Landmarks overallStatus: COMPLETED date: 2022-09-10 date: 2023-08-05 date: 2023-12-17 date: 2024-04-17 date: 2024-04-17 name: Ondokuz Mayıs University class: OTHER briefSum... |
<|newrecord|> nctId: NCT06369493 id: OMUKAEK: 2022/210 briefTitle: Examining The Relationship Between Gingival Thickness and Tooth and Gingival Parameters overallStatus: COMPLETED date: 2022-09-01 date: 2023-12-01 date: 2023-12-18 date: 2024-04-17 date: 2024-04-17 name: Ondokuz Mayıs University class: OTHER briefSummar... |
<|newrecord|> nctId: NCT06369480 id: Journal-nr.: R-23057752 briefTitle: Prognostic Factors for Survival in Patients With Cholangiocarcinoma overallStatus: RECRUITING date: 2024-02-01 date: 2024-08-31 date: 2024-08-31 date: 2024-04-17 date: 2024-04-17 name: Rigshospitalet, Denmark class: OTHER briefSummary: The objecti... |
<|newrecord|> nctId: NCT06369467 id: R5458-668-ALG-2219 id: 2024-511032-27-00 type: REGISTRY domain: EU CT Number briefTitle: Short-Term Linvoseltamab Treatment, on Top of Chronic Dupilumab Treatment, for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy overallStatus: NOT_YET_RECRUITING date: 2024-04-12 ... |
The study is looking at several other research questions, including: |
* What side effects may happen from taking the study drugs |
* Whether linvoseltamab when combined with dupilumab has an effect on other types of antibodies in the blood at different times |
* How much study drug(s) is in the blood at different times conditions: Food Allergy studyType: INTERVENTIONAL phases: PHASE1 allocation: NA interventionModel: SEQUENTIAL primaryPurpose: TREATMENT masking: NONE count: 6 type: ESTIMATED name: linvoseltamab name: dupilumab measure: Incidence of treatment-emergent adverse... |
<|newrecord|> nctId: NCT06369454 id: B7981090 briefTitle: A Study to Learn About How Different Forms of the Study Medicine Called Ritlecitinib Pass the Intestines of Healthy Male Adults When Taken With or Without Food overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2024-08-03 date: 2024-08-03 date: 2024-04-17 ... |
This study is seeking healthy participants who have: |
* Aged 18 years or older; |
* male who are healthy as determined by medical assessment; |
* BMI of 16-32 kg/m2, and a total body weight \>45 kg (99 lb). |
All participants in this study will receive a ritlecitinib oral dose in two different forms (solution without food, capsule with or without food). |
The study will take up to 3 months, including the screening period and follow-up phone call. Participants will have to stay at the study clinic for at least 11 days. There will be 3 periods in total, and a washout period of at least 3 days between dosings in Period 1 and Period 2, and at least 7 days between dosings in... |
<|newrecord|> nctId: NCT06369441 id: Ovation-23-001 briefTitle: Collection of Biological Specimens and Associated Health Information overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2034-04 date: 2024-04-17 date: 2024-04-17 name: Ovation.io, Inc. class: INDUSTRY briefSummary: The purpose of this stud... |
<|newrecord|> nctId: NCT06369428 id: CDRB436BFI02 briefTitle: Patient Characteristics, Treatment Patterns, and Healthcare Resource Utilization of Metastatic Melanoma Patients overallStatus: COMPLETED date: 2021-06-23 date: 2023-04-13 date: 2023-04-13 date: 2024-04-17 date: 2024-04-17 name: Novartis class: INDUSTRY brie... |
<|newrecord|> nctId: NCT06369415 id: 04/24/DD-BVMD briefTitle: Health of Babies Born From IVF Versus IVM at 5 Years Old acronym: FM-BABIES-5Y overallStatus: RECRUITING date: 2024-04-16 date: 2025-12-30 date: 2026-03-30 date: 2024-04-17 date: 2024-04-17 name: Mỹ Đức Hospital class: OTHER briefSummary: The investigators ... |
<|newrecord|> nctId: NCT06369402 id: 0963 briefTitle: Cognitive Impairment and Cerebral Haemodynamics in Individuals With Symptomatic Peripheral Arterial Disease acronym: CInCH PAD overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-02 date: 2025-02 date: 2024-04-17 date: 2024-04-25 name: University of Leicester... |
Arterial disease of the legs causes symptoms such as pain when walking and may ultimately lead to a leg amputation. Many older people with arterial disease of the legs also have problems with their thinking and memory. Blood flow in the brain may be altered in these people and may be a cause for memory and thinking pro... |
Aim: |
The aim of this project is to investigate whether people with arterial disease of the legs have altered blood flow in the brain causing problems with memory and thinking. |
Research plan: |
Twenty people with arterial disease of the legs causing pain while walking and twenty healthy people will have a series of non-invasive assessments. Arterial disease in the legs will be measured using ankle blood pressures before and after walking. Blood flow in the brain will be measured using ultrasound whilst perfor... |
Benefits to society: |
This project will help determine if there is a link between arterial disease of the legs and memory and thinking problems caused by altered blood flow in the brain. It will enable future research in people with cognitive impairment caused by altered blood supply to the brain and to prevent confusion and further memory ... |
<|newrecord|> nctId: NCT06369389 id: RC31/23-0417 briefTitle: Real-life Management of Patients Eligible for CAR-T Cell Therapy acronym: CARAVAGE overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2033-12-31 date: 2034-12-31 date: 2024-04-17 date: 2024-04-17 name: University Hospital, Toulouse class: OTHER name: L... |
With the increasing number of indications and candidate patients, Toulouse University Hospital, the only healthcare facility authorized in the Western Occitanie region to administer CAR-T cells, is faced with growing hospital needs and longer treatment times. In 2023, this has necessitated the implementation of new amb... |
The creation of a registry of patients eligible for CAR-T cells at Toulouse University Hospital will enable these lines of research to be explored on the scale of a region with a population of 3 million. conditions: Hemopathy studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: CROSS_SECTIONAL count: 55... |
<|newrecord|> nctId: NCT06369376 id: ONZ-2022-0072 briefTitle: Electrodiagnostic Approach for Pectoral Nerve Conduction Studies overallStatus: COMPLETED date: 2023-06-30 date: 2023-11-29 date: 2024-04-12 date: 2024-04-17 date: 2024-04-17 name: University Hospital, Ghent class: OTHER briefSummary: Anatomical studies hav... |
A study on 25 volunteers was conducted, examining the three parts of the pectoral nerve. Electrode placement followed a detailed methodology ensuring precise data collection. The nerve conduction study was performed bilaterally, exploring latency and amplitude while addressing inter-observer variability and demographic... |
<|newrecord|> nctId: NCT06369363 id: STUDY000024245 briefTitle: Estrogen Deficiency on Cardiovascular Risk overallStatus: NOT_YET_RECRUITING date: 2025-09 date: 2027-09 date: 2027-11 date: 2024-04-17 date: 2024-04-17 name: Milton S. Hershey Medical Center class: OTHER briefSummary: To explore how estrogen deficiency im... |
<|newrecord|> nctId: NCT06369350 id: STUDY000020217 id: 940567 type: OTHER_GRANT domain: American Heart Association briefTitle: Vitamin B6 on Exercise Pressor Reflex on Leg Ischemia-reperfusion overallStatus: NOT_YET_RECRUITING date: 2024-09 date: 2025-09 date: 2025-09 date: 2024-04-17 date: 2024-04-17 name: Milton S. ... |
<|newrecord|> nctId: NCT06369337 id: 014-24 briefTitle: Ultrasound Study of the Submentonian Musculature and Its Relationship in Dysphagia overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2025-04 date: 2025-06 date: 2024-04-17 date: 2024-04-22 name: Universidad Europea de Madrid class: OTHER name: Hospital Univers... |
<|newrecord|> nctId: NCT06369324 id: 05 briefTitle: Efficacy of Pain Neuroscience Education and Physiotherapy in Patients Diagnosed With Spondyloarthritis overallStatus: RECRUITING date: 2024-02-15 date: 2024-04-11 date: 2024-04-11 date: 2024-04-17 date: 2024-04-18 name: Universidad de Extremadura class: OTHER briefSum... |
Management strategies encompass a multidisciplinary approach, with physiotherapy emerging as a cornerstone therapeutic modality. Various exercise interventions, particularly those supervised by trained professionals, demonstrate efficacy in improving pain, stiffness, and overall functional capacity. Furthermore, patien... |
The evolving landscape of spondyloarthritis management underscores the necessity of further research into multimodal treatment approaches, particularly in integrating novel interventions such as electrophysical agents. By elucidating the mechanisms of action and exploring their synergistic effects, clinicians can refin... |
<|newrecord|> nctId: NCT06369311 id: 2000037345 briefTitle: [Trial of device that is not approved or cleared by the U.S. FDA] overallStatus: WITHHELD date: 2024-04-17 date: 2024-04-17 name: [Redacted] hasResults: False |
<|newrecord|> nctId: NCT06369298 id: JK07.2.01 briefTitle: Study of JK07 in Patients With Chronic Heart Failure acronym: RENEU-HF overallStatus: RECRUITING date: 2024-03-28 date: 2025-12-31 date: 2026-06-30 date: 2024-04-16 date: 2024-04-18 name: Salubris Biotherapeutics Inc class: INDUSTRY briefSummary: This is a Phas... |
There will be 2 cohorts in this study: |
Cohort 1: Heart failure (HF) participants with left ventricular ejection fraction (LVEF) of ≤ 40%. |
Cohort 2: Heart failure (HF) participants with left ventricular ejection fraction (LVEF) \> 40% and ≤ 65%. |
Participants in both cohorts will be randomized into either low dose JK07, high dose JK07 or placebo. Participants will have a 2:1 chance of receiving JK07 versus placebo. conditions: Heart Failure With Reduced Ejection Fraction conditions: Heart Failure With Preserved Ejection Fraction studyType: INTERVENTIONAL phases... |
<|newrecord|> nctId: NCT06369285 id: PUMA-ALI-1201 id: 2024-511497-79-00 type: CTIS briefTitle: A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer acronym: ALISCA-Breast1 overallStatus: NOT_YET_RECRUITING date: 2024-12-31 date: 20... |
<|newrecord|> nctId: NCT06369272 id: mRNA-1273-P919 briefTitle: Study to Assess Maternal and Infant Outcomes Following Exposure to SPIKEVAX During Pregnancy overallStatus: COMPLETED date: 2023-03-01 date: 2023-10-20 date: 2023-10-20 date: 2024-04-16 date: 2024-04-16 name: ModernaTX, Inc. class: INDUSTRY briefSummary: T... |
In infants of women exposed to SPIKEVAX during pregnancy, to assess: |
* If exposure to SPIKEVAX during pregnancy is associated with an increased birth prevalence of major congenital malformations (MCMs). |
* If exposure to SPIKEVAX during pregnancy is associated with an increased birth prevalence of adverse neonatal and infant outcomes, specifically neonatal encephalopathy, small for gestational age, respiratory distress in the newborn, and incidence of hospitalization due to infections including coronavirus disease 2019... |
* In women exposed to SPIKEVAX during pregnancy, to assess whether exposure to SPIKEVAX is associated with an increased prevalence of hypertensive disorders \[e.g., pre-eclampsia, eclampsia, and gestational hypertension\] gestational diabetes, and post-partum hemorrhage; and |
* To assess whether exposure to SPIKEVAX during pregnancy is associated with an increased incidence of stillbirth, preterm birth, and medically attended spontaneous abortion. conditions: Maternal Outcomes conditions: Infant Outcomes conditions: Pregnancy studyType: OBSERVATIONAL observationalModel: COHORT timePerspecti... |
<|newrecord|> nctId: NCT06369259 id: 2023-0997 id: NCI-2024-03302 type: OTHER domain: NCI-CTRP Clinical Registry briefTitle: Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cance... |
<|newrecord|> nctId: NCT06369246 id: 2023-0893 id: NCI-2024-03308 type: OTHER domain: NCI-CTRP Clinical Registry briefTitle: PRORAD-5 PROstate RADiation in 5 Fractions: Phase Ib Five Fraction Radiotherapy for Patients With Advanced Prostate Cancer overallStatus: NOT_YET_RECRUITING date: 2024-10-31 date: 2025-09-01 date... |
<|newrecord|> nctId: NCT06369233 id: LNC-MS-002 briefTitle: Clinical Study to Evaluate the Anti-adhesion Efficacy and Safety of MegaShield®-SP in Comparison With Guardix-SP Plus After Spine Surgery overallStatus: RECRUITING date: 2024-04-01 date: 2025-02-28 date: 2025-02-28 date: 2024-04-16 date: 2024-04-25 name: L&C B... |
<|newrecord|> nctId: NCT06369220 id: LIA-STI-542 briefTitle: A Study of the Cobas® Liat CT/NG/MG Test Versus Current Standard Practice for Managing Participants at Increased Risk of Sexually Transmitted Infections overallStatus: NOT_YET_RECRUITING date: 2024-06-15 date: 2024-10-31 date: 2024-10-31 date: 2024-04-16 date... |
<|newrecord|> nctId: NCT06369207 id: 113454 briefTitle: Investigation of the Transmission Pathways of Reflux in Patients With Chronic Venous Evaluation of Reflux Transmission Pathways in Chronic Venous Insufficiency Patients Secondary to Saphenofemoral Reflux overallStatus: ACTIVE_NOT_RECRUITING date: 2023-09-12 date: ... |
<|newrecord|> nctId: NCT06369194 id: POWER5 briefTitle: POWER AUDIT, Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol overallStatus: ACTIVE_NOT_RECRUITING date: 2023-11-14 date: 2024-04-15 date: 2024-04-15 date: 2024-04-16 date: 2024-04-19 name: Grupo Español de Rehabilitación Multimodal class:... |
It is proposed to review the medical records of oncology patients included in POWER 1 (as already foreseen in that study), with the aim of performing a 5-year follow-up. |
To create comparable treatment and control groups, the Propensity Index method will be used. To study each variable, multivariate regression will be used. Kaplan-Meier will be used for survival and the log-rank test for comparisons. Significance will be considered if p \<0.05 (two tails). conditions: Colorectal Surgery... |
<|newrecord|> nctId: NCT06369181 id: NET 2020 briefTitle: Neuroendocrine Transformation in RB1/TP53 Inactivated NSCLC overallStatus: RECRUITING date: 2021-01-01 date: 2027-12-31 date: 2028-12-31 date: 2024-04-16 date: 2024-04-23 name: Fudan University class: OTHER briefSummary: Histology transformation from non-small c... |
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