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Participant Duration: Approximately 1 year. |
Aims: |
Aim 1 - Evaluate adherence and treatment completion rates when glecaprevir-pibrentasvir is started during pregnancy for women who use drugs. |
Aim 2 - Evaluate patient experience with hepatitis C virus treatment during pregnancy. conditions: Hepatitis C conditions: Pregnancy Complications studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 50 type: ESTIMATED name: Glecaprevir-pibrentasvir measure: Medication adherence and t... |
<|newrecord|> nctId: NCT06367452 id: CAEP 107.001.23 briefTitle: Exploratory Pilot Study to Evaluate the Pharmacokinetic Profile of Magaldrate overallStatus: COMPLETED date: 2023-10-31 date: 2024-01-15 date: 2024-03-30 date: 2024-04-16 date: 2024-04-16 name: Tecnoquimicas class: INDUSTRY briefSummary: The goal of this ... |
Participants will take the medication 30 minutes after a standard breakfast. Both groups of participants will take the standard meal but one group will take the medication and the other one won't. |
Researchers will compare the levels of both ions in plasma in a group to see if there is any absorption, quantifying the basal plasma levels and comparing with the levels obtained after the meal and the medication, when it applies. conditions: Healthy studyType: INTERVENTIONAL phases: PHASE4 allocation: RANDOMIZED inte... |
<|newrecord|> nctId: NCT06367439 id: FN-10984 briefTitle: Examining the Effects of Virtual Reality Exercise on Mental Health acronym: UVIC VR Fit overallStatus: RECRUITING date: 2024-03-19 date: 2025-06 date: 2025-06 date: 2024-04-16 date: 2024-04-26 name: University of Victoria class: OTHER name: Meta Platforms, Inc. ... |
<|newrecord|> nctId: NCT06367426 id: Pharmacobio briefTitle: A Phase I Study of DDN-A-0101 in Healthy Volunteers and Elder People overallStatus: RECRUITING date: 2024-04 date: 2025-05 date: 2025-05 date: 2024-04-16 date: 2024-04-16 name: Pharmacobio class: INDUSTRY briefSummary: The study is a Phase I, randomized doubl... |
<|newrecord|> nctId: NCT06367413 id: UTH-PRoNAC Study briefTitle: Effects of Protein and NAC Co-ingestion on Skeletal Muscle Recovery acronym: PRoNAC overallStatus: RECRUITING date: 2024-04-08 date: 2024-06-20 date: 2024-09-30 date: 2024-04-16 date: 2024-04-16 name: University of Thessaly class: OTHER briefSummary: Pre... |
<|newrecord|> nctId: NCT06367400 id: SwePSQ briefTitle: Validation of Pediatric Sleep Questionnaire on a Swedish Cohort overallStatus: RECRUITING date: 2024-03-01 date: 2024-12-31 date: 2034-12-31 date: 2024-04-16 date: 2024-04-16 name: Uppsala University class: OTHER name: Karolinska Institutet name: Örebro University... |
<|newrecord|> nctId: NCT06367387 id: STUDY23080191 id: RM1DA055311 type: NIH link: https://reporter.nih.gov/quickSearch/RM1DA055311 briefTitle: Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment acronym: TREETOP overallStatus: NOT_YET_RECRUITING date: 2024-05 date: 2025-12 date:... |
The research study is testing two different interventions along with usual clinical care: |
1. Pain Self-Management (PSM): an educational program in which individuals with chronic pain work with a trained pain coach and a pain peer to explore strategies to effectively manage the daily problems that arise from chronic pain. |
2. Patient-Oriented Dosing (POD): an alternative dosing of buprenorphine which will be adjusted based on pain levels. |
The interventions will take place over a period of 12 weeks (3 months). Additionally, participants will complete surveys every 3 months for a period of 1 year (total of 5 survey visits). Participants will receive $50 compensation for each survey visit completed (up to $250 over one year) and can receive up to an additi... |
There are risks associated with participating in the study, including breach of confidentiality, psychological distress caused by discussing difficult topics, and risks associated with the POD intervention. conditions: Opioid Use Disorder conditions: Chronic Pain studyType: INTERVENTIONAL phases: PHASE4 allocation: RAN... |
<|newrecord|> nctId: NCT06367374 id: BGB-11417-2002-IIT；BDH-CLL-004 briefTitle: MRD Guided Sonrotoclax and Zanubrutinib in Newly Diagnosed CLL/SLL overallStatus: NOT_YET_RECRUITING date: 2024-05-30 date: 2030-02-28 date: 2030-07-30 date: 2024-04-16 date: 2024-04-16 name: Institute of Hematology & Blood Diseases Hospita... |
The primary goal of this study is to evaluate the efficacy of MRD-guided zanubrutinib plus sonrotoclax for first-line CLL/SLL treatment. conditions: Chronic Lymphocytic Leukemia conditions: Small Lymphocytic Lymphoma studyType: INTERVENTIONAL phases: PHASE2 allocation: NA interventionModel: SINGLE_GROUP primaryPurpose:... |
<|newrecord|> nctId: NCT06367361 id: SIDISI 201221 id: U01AI155323 type: NIH link: https://reporter.nih.gov/quickSearch/U01AI155323 briefTitle: One and Two Doses of Oxfendazole Versus a Schedule of Two Doses of Triclabendazole in Chronic Fascioliasis overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2028-03 date: 2... |
Study arm 2: Oxfendazole 100 mg tablets at 20 mg/kg of body weight per dose in two oral doses separated 24 hours each administered with a lipid containing meal under direct observation. |
Study arm 3: Triclabendazole 250 mg tablets at 10 mg/kg of body weight per dose in two oral doses separated 24 hours each administered with a lipid containing meal under direct observation. primaryPurpose: TREATMENT masking: DOUBLE maskingDescription: The laboratory personnel processing the stool microscopy tests will ... |
<|newrecord|> nctId: NCT06367348 id: R01AA031445 type: NIH link: https://reporter.nih.gov/quickSearch/R01AA031445 id: R01AA031445 type: NIH link: https://reporter.nih.gov/quickSearch/R01AA031445 briefTitle: An Economic and Relationship-strengthening Intervention to Reduce Alcohol Use in Malawi overallStatus: NOT_YET_RE... |
<|newrecord|> nctId: NCT06367335 id: ETIC briefTitle: Characteristics and Predictors of Liver Injury in Cyclin-dependent Kinase Inhibitors 4/6 (CDK4/6)-Treated Patients With Advanced Breast Cancer acronym: ETIC overallStatus: COMPLETED date: 2022-06-01 date: 2022-09-01 date: 2022-12-31 date: 2024-04-16 date: 2024-04-16... |
<|newrecord|> nctId: NCT06367322 id: EMP-PARA-20170-01 briefTitle: Statins and Post-ERCP Acute Pancreatitis (Stark Project) acronym: Stark overallStatus: COMPLETED date: 2017-01-10 date: 2018-07-31 date: 2018-09-30 date: 2024-04-16 date: 2024-04-16 name: Hospital General Universitario de Alicante class: OTHER name: Eur... |
<|newrecord|> nctId: NCT06367309 id: 2023 - 02357 briefTitle: ExtrAperitoneaL Plasty vs Intraperitoneal oNlay mEsh in Ventral Hernia Repair acronym: ALPINE overallStatus: NOT_YET_RECRUITING date: 2024-04-30 date: 2025-12-31 date: 2030-12-31 date: 2024-04-16 date: 2024-04-16 name: University Hospital, Basel, Switzerland... |
The goal of this clinical trial is to learn if the eTEP (Extended totally extraperitoneal repair) technique leads to a better outcome than the IPOM (Intraperitoneal onlay mesh) technique. |
The main questions it aims to answer are: |
* pain after the operation |
* rate of complications |
* rate of recurrence and reoperations |
* quality of life. |
Participants will: |
Either be operated using the eTEP or the IPOM technique. Be followed up either in person or via email / phone call at day 1, day 7, day 14, 6 weeks, 6 months, 1, 3 and 5 years after the surgery to asses the above-stated main and some more outcomes. conditions: Ventral Hernia conditions: Abdominal Wall Defect studyType:... |
<|newrecord|> nctId: NCT06367296 id: RETOPO2024 briefTitle: Resistance Exercise Training in the Older Population With Obesity acronym: RETOPO overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-01-28 date: 2025-06-01 date: 2024-04-16 date: 2024-04-16 name: Universidad de La Frontera class: OTHER briefSummary:... |
Aging leads to an alteration in the immune response, characterized by a chronic inflammatory state, and a progressive decrease in muscle quantity and quality, a situation that increases in women and in the presence of obesity. With respect to muscle quality, intramuscular infiltration of adipose tissue has been conside... |
Hypothesis: |
A 12-week resistance exercise training program is effective in improving muscle quality, immune response and physical performance in normal weight and obese older women. In addition to the above, the investigators hypothesize that women with obesity will present greater baseline alterations, so the percentage of change... |
Goals: |
The primary aim of this study is to evaluate the effects of a 12-week resistance exercise training on muscle quality (infiltration of intramuscular adipose tissue), immune response and physical performance in older women between 60 and 79 years of age with obesity compared to older women with normal weight of the same ... |
Methodology: |
The present clinical trial will consider 2 groups of older women between 60 and 79 years old: normal weight (BMI=18.5 to 24.9 kg/m 2 and % fat \<25.9) and obese (BMI =30 to 39.9 Kg/m 2 and fat % \>32). Participants will perform 12 weeks of training with resistance exercises 3 times a week. Before and after training, in... |
<|newrecord|> nctId: NCT06367283 id: 2023-509181-38-00 briefTitle: Metformin Treatment of Patients With Hand Osteoarthritis acronym: METRO overallStatus: NOT_YET_RECRUITING date: 2024-06 date: 2025-12 date: 2026-04 date: 2024-04-16 date: 2024-04-16 name: Marius Henriksen class: OTHER briefSummary: To compare metformin ... |
<|newrecord|> nctId: NCT06367270 id: UW 23-361 briefTitle: The Application of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) for Peritoneal Surface Malignancies acronym: PIPAC overallStatus: RECRUITING date: 2023-09-01 date: 2026-08-31 date: 2027-08-31 date: 2024-04-16 date: 2024-04-16 name: The University of H... |
<|newrecord|> nctId: NCT06367257 id: Emento App briefTitle: App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-04-30 date: 2026-06-30 date: 2024-04-16 date: 2024-04-16 nam... |
<|newrecord|> nctId: NCT06367244 id: TWP2023 briefTitle: Transplant Wellness Program acronym: TWP overallStatus: RECRUITING date: 2023-11-16 date: 2033-11 date: 2033-11 date: 2024-04-16 date: 2024-04-16 name: University of Calgary class: OTHER briefSummary: Wellness is defined as the active pursuit of activities, choic... |
<|newrecord|> nctId: NCT06367231 id: Pro00134554 briefTitle: SCGs as a Proxy for Determining the Cognitive Status of Older Adults overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-05-01 date: 2025-07-01 date: 2024-04-16 date: 2024-04-16 name: University of Alberta class: OTHER briefSummary: Detecting memory... |
In our study, we are investigating the potential of computer games to reflect the cognitive skills of older adults. We developed the VibrantMinds platform, featuring five games: Whack-a-Mole, Bejeweled, Mahjong Solitaire, Word Search, and Memory Game. We have evaluated these games for ease of use, enjoyment, and their ... |
We are collecting demographic data, game-playing data, and cognitive test results. Our analysis will determine the correlation between game data, cognitive test outcomes, and demographic information. Additionally, we will assess both the perceived and observed engagement of older adults as they play the games. conditio... |
<|newrecord|> nctId: NCT06367218 id: S058 briefTitle: Opioid-Free Combined Anesthesia With Spontaneous Breathing for VATS overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-07-01 date: 2026-08-01 date: 2024-04-16 date: 2024-04-16 name: Tongji Hospital class: OTHER briefSummary: Non-tracheal intubated combine... |
<|newrecord|> nctId: NCT06367205 id: LY2023-135-A briefTitle: Norepinephrine Infusion Combined With Goal-directed Fluid Therapy in Patients Undergoing Kidney Transplantations overallStatus: RECRUITING date: 2024-03-01 date: 2026-04-30 date: 2026-06-30 date: 2024-04-16 date: 2024-04-16 name: RenJi Hospital class: OTHER ... |
<|newrecord|> nctId: NCT06367192 id: SKITS2 id: K23HL166697 type: NIH link: https://reporter.nih.gov/quickSearch/K23HL166697 briefTitle: School Readiness Intervention for Preschool Children With Sickle Cell Disease overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-10 date: 2028-10 date: 2024-04-16 date: 2024-0... |
Primary Objective |
Assess feasibility and acceptability of an adapted school readiness intervention among preschool children (ages 4-6) diagnosed with sickle cell disease. |
Secondary Objectives |
Objective 1: |
Measure preliminary efficacy of the adapted school readiness intervention compared to routine care among preschool children ages (4-6) diagnosed with sickle cell disease. |
Objective 2: |
Examine implementation factors (i.e., barriers and facilitators) during post-intervention. conditions: Sickle Cell Disease studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: SINGLE_GROUP primaryPurpose: TREATMENT masking: NONE count: 36 type: ESTIMATED name: The adapted Kids in Transition to... |
<|newrecord|> nctId: NCT06367179 id: 202401039RINC briefTitle: Virtual Reality and AI Wound-detecting System overallStatus: RECRUITING date: 2024-03-22 date: 2025-02-04 date: 2025-02-04 date: 2024-04-16 date: 2024-04-16 name: National Taiwan University Hospital class: OTHER briefSummary: This study is an experimental s... |
<|newrecord|> nctId: NCT06367166 id: RyazanSMU briefTitle: Effects of Bioflavanoids on Vascular Wall Remodeling in Patients With Varicose Veins overallStatus: ACTIVE_NOT_RECRUITING date: 2023-04-01 date: 2026-04-01 date: 2026-05-01 date: 2024-04-16 date: 2024-04-16 name: Ryazan State Medical University class: OTHER bri... |
<|newrecord|> nctId: NCT06367153 id: 1447-0007 id: 2023-510461-10-00 type: REGISTRY domain: CTIS id: U1111-1303-9187 type: REGISTRY domain: WHO International Clinical Trials Registry Platform (ICTRP) briefTitle: A Study in Healthy Men and Women to Test Whether BI 1569912 Influences the Amount of Repaglinide, Midazolam ... |
<|newrecord|> nctId: NCT06367140 id: SYU 2021-06-001-002 briefTitle: Effects of Electromyography-Triggered Constraint-Induced Movement Cycling Therapy on Patients With Chronic Stroke overallStatus: COMPLETED date: 2020-01-01 date: 2022-12-31 date: 2023-12-31 date: 2024-04-16 date: 2024-04-17 name: Sahmyook University c... |
<|newrecord|> nctId: NCT06367127 id: Pingfanghu briefTitle: Utility of the Clamping Bean Test (CBT) for Covert Hepatic Encephalopathy Screening overallStatus: ENROLLING_BY_INVITATION date: 2023-10-09 date: 2024-12-31 date: 2024-12-31 date: 2024-04-16 date: 2024-04-16 name: Shanghai Changzheng Hospital class: OTHER brie... |
Presently, the diagnosis of CHE depends on psychometric and neurophysiological tests, including the psychometric hepatic encephalopathy score (PHES), critical flicker frequency (CFF) test, continuous reaction time (CRT) test, inhibitory control test, the SCAN test, and electroencephalography. Among them, PHES is most w... |
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