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1. Intra-articular displacement of ⩾ 2 mm |
2. Metaphyseal -diaphyseal translation \> 1 cm |
3. Angular deformity more than 10 degree in the coronal or sagittal view |
4. Open fracture , compartment syndrome and associated ligament injury require repair. |
5. Associated fractures of the ipsilateral tibia or fibula |
Frequently the depressed articular fragments have to elevated back toward the knee , followed by fixation and sometimes supplemented with bone graft to fill any cancellous bone voids left beneath the joint surface after fracture reduction . |
We will evaluate treatment outcomes of closed reduction and percutaneous cannulated screw fixation for tibial plateau fractures versus open reduction and fixation by plate conditions: Tibial Plateau Fractures Schatzker Type II studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL prima... |
<|newrecord|> nctId: NCT06353035 id: NaturalResourcesIFinland id: 346136 type: OTHER_GRANT domain: Strategic Research Council Finland id: 346138 type: OTHER_GRANT domain: Strategic Research Council Finland briefTitle: Biodiversity Interventions for Well-Being acronym: BIWE overallStatus: ACTIVE_NOT_RECRUITING date: 202... |
In Biodiversity interventions for well-being (BIWE), microbial biodiversity interventions are performed to increase biodiversity in urban built areas. Results from the intervention trials are combined with publicly available land cover and ecological data. These are analyzed from the viewpoint of shifts in ecosystems a... |
The investigators set up an intervention study in which urban private yards are rewilded with diverse vegetation and decaying deadwood and plant residuals. The investigators aim to evaluate the effect of rewilding, and yard management practices on commensal microbiome, cortisol levels and well-being and salivary cytoki... |
<|newrecord|> nctId: NCT06353022 id: RC23_0267 id: 2023-508310-41 type: EUDRACT_NUMBER briefTitle: Minimal Residual Disease-based Strategy With T-Cell Redirector After Treatment With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone (D-VRd) in Newly Diagnosed Multiple Myeloma acronym: IFm2022-01 overallStatus: N... |
The patient population will consist of adults men and women at least 18 years to younger than 66 years of age, who meet eligibility criteria. conditions: Multiple Myeloma studyType: INTERVENTIONAL phases: PHASE2 allocation: NON_RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: NONE count: 103 ty... |
<|newrecord|> nctId: NCT06353009 id: ICM 2021-2720 briefTitle: Effect of a Single Ultra-Processed Meal on Myocardial Endothelial Function Assessed With Positron Emission Tomography acronym: SUPPER overallStatus: COMPLETED date: 2020-08-20 date: 2023-04-28 date: 2023-04-28 date: 2024-04-08 date: 2024-04-08 name: Matthie... |
The proposed study is an open-label, randomized crossover clinical trial. Participants will be divided into 2 groups: half of the participants will consume a Mediterranean meal during the first experimental visit and an ultra-processed meal during the second, and vice versa for the other half. The order in which the me... |
This project will contribute to clarify the role of diet in the development and progression of coronary artery disease. The results obtained from this study may potentially demonstrate the harmful effect of ultra-processed foods, even in the short term, on coronary arteries. conditions: Myocardial Endothelial Function ... |
<|newrecord|> nctId: NCT06352996 id: Dentist Anas Kassas briefTitle: Three-Dimensional Assessment of Maxillary Canine Retraction With and Without Power Arm overallStatus: ACTIVE_NOT_RECRUITING date: 2023-06-09 date: 2024-03-09 date: 2024-07-30 date: 2024-04-08 date: 2024-04-08 name: Mansoura University class: OTHER bri... |
Materials and methods:Twenty patients with age range between 14 to 25 years. Before bonding, a hook will be attached to the canine bracket in one side only. Leveling and alignment then The first premolars will be extracted and mini-implant will be inserted. |
Canine retraction using nickel titanium closed coil spring will start in the same day of upper first premolar extraction. conditions: Power Arm Canine Retraction studyType: INTERVENTIONAL phases: NA allocation: RANDOMIZED interventionModel: PARALLEL primaryPurpose: TREATMENT masking: SINGLE whoMasked: OUTCOMES_ASSESSOR... |
<|newrecord|> nctId: NCT06352983 id: 2014/11 briefTitle: Zirconium Dioxide Fixed Dental Prosthesis. overallStatus: COMPLETED date: 2017-12-20 date: 2019-09-27 date: 2023-01-20 date: 2024-04-08 date: 2024-04-08 name: Malmö University class: OTHER briefSummary: The purpose of this clinical trial is to evaluate and compar... |
<|newrecord|> nctId: NCT06352970 id: LundU-2024 briefTitle: Effects of Tuberculosis Infection on Development and Function of the Placenta overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2025-12-31 date: 2027-12-31 date: 2024-04-08 date: 2024-04-08 name: Lund University class: OTHER name: Addis Ababa University... |
The main questions it aims to answer are: |
* Does TB infection affect the structure of the placenta? |
* Does TB infection affect the function of the placenta? |
Pregnant women attending delivery clinics in Addis Abeba, Ethiopia, will be enrolled and classified for TB infection using a blood-based test. We will compare the following outcomes between women with TB infection and women without TB infection: |
* Pathological lesions of the placenta |
* Gene and protein expression patterns linked to pregnancy-related disorders |
* Infant outcome at birth and at 6 weeks after birth conditions: Pregnancy Related conditions: Tuberculosis Infection conditions: Placenta Diseases studyType: OBSERVATIONAL observationalModel: COHORT timePerspective: PROSPECTIVE count: 500 type: ESTIMATED name: TB infection measure: Proportion of women with pathologica... |
<|newrecord|> nctId: NCT06352957 id: 23022022CERC briefTitle: Use of ETElcalcetidefor pReserving vitamiN K-dependent proteIn activiTY ITAlian Study acronym: ETERNITY-ITA overallStatus: NOT_YET_RECRUITING date: 2024-05-01 date: 2026-12-31 date: 2027-12-31 date: 2024-04-08 date: 2024-04-08 name: Istituto di Fisiologia Cl... |
The study will enroll 160 hemodialysis patients: 80 patients treated with Etelcalcetide and 80 age and sex matched patients treated with Calcitriol or vitamin D analogs. The treating nephrologist will base the target dose of Etelcalcetide on individual-level in order to achieve the KDIGO PTH target. In the Etelcalcetid... |
<|newrecord|> nctId: NCT06352944 id: AssiutMD briefTitle: Procalcitonin as a Marker of Severity of Non-cystic Fibrosis Bronchiectasis in Children overallStatus: NOT_YET_RECRUITING date: 2024-07 date: 2025-07 date: 2026-07 date: 2024-04-08 date: 2024-04-17 name: Assiut University class: OTHER briefSummary: The aim of th... |
<|newrecord|> nctId: NCT06352931 id: TCD & TCUS in infants briefTitle: Transcranial Ultrasound and Transcranial Doppler in Diagnosis and Detection of Outcome in Infants With Neurological Diseases overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2025-06-30 date: 2025-07-30 date: 2024-04-08 date: 2024-04-08 name:... |
<|newrecord|> nctId: NCT06352918 id: B.30.2.ATA.0.01.00/395 briefTitle: Peripheral Central Catheter (PICC) Care acronym: PICC overallStatus: COMPLETED date: 2023-05-01 date: 2023-11-30 date: 2023-12-31 date: 2024-04-08 date: 2024-04-08 name: Ataturk University class: OTHER briefSummary: Peripheral Central Catheter (PIC... |
Today, it is accepted that tactile stimuli, which have a pain-reducing effect on babies, should be used as a complementary treatment and care method. Palmar grasp reflex is one of the important tactile stimuli to reduce pain and provide comfort in babies. This research will be conducted to examine the effect of palmar ... |
<|newrecord|> nctId: NCT06352905 id: 2157711 briefTitle: Acute Effects of Whole Body Vibration for Individuals With Parkinson Disease overallStatus: RECRUITING date: 2022-09-01 date: 2025-04 date: 2025-04 date: 2024-04-08 date: 2024-04-08 name: Baylor University class: OTHER name: University of St. Augustine for Health... |
<|newrecord|> nctId: NCT06352892 id: 20210201 briefTitle: A Study to Evaluate AMG 133 in Chinese Participants With Obesity or Overweight overallStatus: NOT_YET_RECRUITING date: 2024-04-24 date: 2024-09-03 date: 2024-09-03 date: 2024-04-08 date: 2024-04-08 name: Amgen class: INDUSTRY briefSummary: The main objective of ... |
<|newrecord|> nctId: NCT06352879 id: 18-Al-KindyCM briefTitle: Prevalence, Types and Risk Factors of Urinary Incontinence Among Women in Baghdad, Iraq. overallStatus: RECRUITING date: 2024-03-01 date: 2024-05-31 date: 2024-06-15 date: 2024-04-08 date: 2024-04-08 name: Al-Kindy College of Medicine class: OTHER briefSumm... |
* What is the prevalence of incontinence among the targeted group? |
* What are the types of incontinence and what is the frequency of each type among the targeted group? |
* What is the effect of several risk factors on the occurrence and severity of urinary incontinence (including age, job, sexual activity, chronic constipation, chronic cough, parity, largest birth weight, and body mass index)? Participants will be asked to fill out a questionnaire consisting of the Arabic International... |
<|newrecord|> nctId: NCT06352866 id: CASE3A23 briefTitle: Siltuximab for Cytokine Release Syndrome Prophylaxis Prior to tx w/ Teclistamab in RRMM overallStatus: NOT_YET_RECRUITING date: 2024-07-01 date: 2025-04-01 date: 2025-12-01 date: 2024-04-08 date: 2024-04-16 name: Jack Khouri class: OTHER briefSummary: The purpos... |
Participants will receive a single dose of prophylactic siltuximab, 11 mg/kg, 2 hours prior to the administration of the first dose of teclistamab on day 1. There is no planned dose escalation of siltuximab, and teclistamab dosing will be done following the standard planned ramp-up. Participants will be hospitalized fo... |
<|newrecord|> nctId: NCT06352853 id: Diathermy and skin incision cs briefTitle: Scalpel Versus Diathermy in Transverse Abdominal Skin Incision During Cesarean Section overallStatus: COMPLETED date: 2022-04-01 date: 2022-09-01 date: 2022-10-01 date: 2024-04-08 date: 2024-04-09 name: Cairo University class: OTHER briefSu... |
<|newrecord|> nctId: NCT06352840 id: HUM00231526 id: 5K23HD099283-03 type: NIH link: https://reporter.nih.gov/quickSearch/5K23HD099283-03 briefTitle: Novel Web-based, Self-directed Intervention for Chronic Pelvic Pain overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2026-04 date: 2026-04 date: 2024-04-08 date: 202... |
The overall hypothesis is that patients with chronic pelvic pain that have access to the My Pelvic Plan program will demonstrate improvements in pain, physical function, and quality of life with this integrative self-management approach. conditions: Chronic Pelvic Pain conditions: Endometriosis studyType: INTERVENTIONA... |
<|newrecord|> nctId: NCT06352827 id: HUM00228948 id: 1K23DK134752-01 type: NIH link: https://reporter.nih.gov/quickSearch/1K23DK134752-01 briefTitle: Guideline to Implementation: A Rapid Clinical Care Pathway to Care for Patients Affected by Chronic Constipation overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 202... |
<|newrecord|> nctId: NCT06352814 id: 1977152 briefTitle: Activities-based Locomotor Training Program Versus Traditional Physical Therapy in Children With Cerebral Palsy overallStatus: RECRUITING date: 2024-03-08 date: 2027-05-30 date: 2027-05-30 date: 2024-04-08 date: 2024-04-08 name: Baylor University class: OTHER bri... |
<|newrecord|> nctId: NCT06352801 id: EA230530 briefTitle: Effectiveness of Self-Compassion Intervention on Enhancing Self-Compassion and Psychological Well-Being of Children With Attention Deficit/Hyperactivity Disorder overallStatus: RECRUITING date: 2023-12-28 date: 2026-05-31 date: 2026-05-31 date: 2024-04-08 date: ... |
The intervention program includes the following components: |
Participants will be randomly assigned to the self-compassion intervention group or the waitlist control group. The intervention group consists of two parts: children training session and parent group sessions. All children participants will complete a total of 6 training sessions, and each session will last around 90 ... |
To investigate the intervention effectiveness, children will be asked to complete a questionnaire assessing their levels of self-compassion, emotional regulation, as well as psychological well-being in terms of life satisfaction, positive and negative affect. Parents and teachers of participants will also be asked to c... |
Study Objectives: |
1. To investigate the underlying mechanism of the relationship between AD/HD traits and psychological well-being |
2. To explore the effectiveness of self-compassion intervention on enhancing self-compassion and psychological well-being of children with AD/HD in Hong Kong |
Hypotheses: |
1. AD/HD traits negatively predicts psychological well-being |
2. AD/HD traits positively predicts perceived criticism or rejection sensitivity |
3. Perceived criticism or rejective sensitivity negatively predicts psychological well-being |
4. Perceived criticism or rejective sensitivity mediates the relationship between AD/HD traits and psychological well-being |
5. Self-compassion moderates the relationship between perceived criticism or rejection sensitivity and psychological well-being |
6. Growth mindset moderates the relationship between perceived criticism or rejection sensitivity and psychological well-being |
7. Children with AD/HD from self-compassion intervention group yield greater improvement in self-compassion, emotional regulation and psychological well-being, than waitlist-control group. conditions: ADHD conditions: Self-Compassion conditions: Psychological Well-Being studyType: INTERVENTIONAL phases: NA allocation: ... |
Wait-list Control: receives the same intervention in Phase 2 primaryPurpose: PREVENTION masking: NONE count: 100 type: ESTIMATED name: Self-Compassion Intervention measure: Self-Compassion Scale for Children (SCS-C) measure: Self-Compassion Scale for Children (SCS-C) measure: Self-Compassion Scale for Children (SCS-C) ... |
<|newrecord|> nctId: NCT06352788 id: 202007224 briefTitle: From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices acronym: AFOSVA overallStatus: NOT_YET_RECRUITING date: 2024-06-01 date: 2027-08-31 date: 2028-09-01 date: 2024-04-08 date: 2024-04-08 name: Jason Wilken class: OTHER name... |
<|newrecord|> nctId: NCT06352775 id: IRB00107112 briefTitle: Calcium Carbonate on Labor Induction overallStatus: NOT_YET_RECRUITING date: 2024-04-01 date: 2024-09-30 date: 2025-12-31 date: 2024-04-08 date: 2024-04-08 name: Aurora Health Care class: OTHER briefSummary: The investigators aim to evaluate the safety and ef... |
<|newrecord|> nctId: NCT06352762 id: Izmir Dokuz Eylul University briefTitle: The Effects of Upper Extremity Robotic Rehabilitation in Children With Spastic Hemiparetic Cerebral Palsy overallStatus: COMPLETED date: 2017-02-15 date: 2017-08-15 date: 2017-12-15 date: 2024-04-08 date: 2024-04-08 name: Izmir Bakircay Unive... |
Methods: 34 hCP patients attended the study. 17 children in the training group recived conventional physiotherapy and Robotic Rehabilitation. 17 children in the control group recived only conventional physiotherapy. Convantional physiotherapy program lasted 45 minutes, Robotic Rehabilitation program lasted 30 minutes. ... |
<|newrecord|> nctId: NCT06352749 id: BasqueCU2024 briefTitle: Face-to-face vs Online Physical Exercise in Seniors Living in Nursing Homes (ExerMOT-NH) acronym: ExerMOT-NH overallStatus: RECRUITING date: 2024-03-18 date: 2025-11-30 date: 2025-11-30 date: 2024-04-08 date: 2024-04-08 name: University of the Basque Country... |
<|newrecord|> nctId: NCT06352736 id: LUTS2023 briefTitle: Status of Disease Burden of Lower Urinary Tract Symptoms in Chinese Male Community overallStatus: RECRUITING date: 2023-06-01 date: 2025-10-01 date: 2025-12-31 date: 2024-04-08 date: 2024-04-15 name: Chinese PLA General Hospital class: OTHER briefSummary: This s... |
<|newrecord|> nctId: NCT06352723 id: 2024P000856 briefTitle: Cenobamate in the Intensive Care Unit acronym: CENOBITE overallStatus: NOT_YET_RECRUITING date: 2024-04 date: 2024-12 date: 2025-06 date: 2024-04-08 date: 2024-04-08 name: Brigham and Women's Hospital class: OTHER briefSummary: The CENOBITE study will be cond... |
Monitoring for the development of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome, a potential adverse reaction, will be a key aspect of the study. Regular assessments, including RegiSCAR scoring (a validated scoring system for DREeSS5), daily serum cenobamate level measurements, and comprehensiv... |
<|newrecord|> nctId: NCT06352710 id: 2022-01510 briefTitle: Determining Postoperative Recovery and the Impact of Adverse Events in Neurosurgery Based on Self-reported, App-based Longitudinal Assessment - a Collaborative Observational Research Project overallStatus: RECRUITING date: 2023-06-12 date: 2025-06-12 date: 202... |
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