panel_design/split/1_top150.csv

Unnamed: 0,Gene symbol,Ranking,Annotation & reasoning,Additional note,Gene Symbol
0,NeuN,1-50,Pan Neuron marker often used for ISH,,NeuN
1,SST,1-50,Defines SST+ Interneurons,,SST
2,PVALB,1-50,Identifies inhibitory interneurons,,PVALB
3,CLND5,1-50,Endothelial cells / Mural cells,,CLND5
4,HBA1,1-50,Endothelial cells / Mural cells,,HBA1
5,ASCA2,1-50,Astrocyte marker often used for Bead collection,,ASCA2
6,GFAP,1-50,Astrocyte marker ,,GFAP
7,CX3CR1 ,1-50,Microglia marker,,CX3CR1 
8,TMEM119,1-50,Microglial marker,,TMEM119
9,AIF1,1-50,IBA1 is often used for in situ hybridzation to label microglial cells. ,,AIF1
10,OLIG2,1-50,"Expressed by OPCs, getting cells ready for differentiation into myelin-forming oligodendocytes. ",,OLIG2
11,CD22,1-50,Expressed by oligodendrocytes in huamns and binds to sialic acid-dependent ligands on microglia. ,,CD22
12,Th,1-50,Often used by ISH of dopaminergic neurons. ,,Th
13,Reln,1-50,"Genes that seperate layers of cortical region (Huuki-Myers, BioRxiv, 2023)",,Reln
14,Aqp4,1-50,"Genes that seperate layers of cortical region (Huuki-Myers, BioRxiv, 2023)",,Aqp4
15,SPARC,1-50,"Genes that seperate layers of cortical region (Huuki-Myers, BioRxiv, 2023)",,SPARC
16,HTRA1,1-50,"Genes that seperate layers of cortical region (Huuki-Myers, BioRxiv, 2023)",,HTRA1
17,VIP,1-50,Labels interneurons in PFC that signal and inhibits SST+ interneurons,,VIP
18,Fos,1-50,Activation-related genes from neurons. ,,Fos
19,Arc,1-50,Activation-related genes from neurons. ,,Arc
20,Egr1,1-50,Activation-related genes from neurons. ,,Egr1
21,BDNF,1-50,"For survival mechanisms of neuronal homeostasis, often associated with disease. ",,BDNF
22,ADORA1,1-50,Neurotransmitter receptors,,ADORA1
23,HTR1A,1-50,Neurotransmitter receptors,,HTR1A
24,HTR2A,1-50,Neurotransmitter receptors,,HTR2A
25,HTR3A,1-50,Neurotransmitter receptors,,HTR3A
26,HTR4,1-50,Neurotransmitter receptors,,HTR4
27,DRD1,1-50,Neurotransmitter receptors,,DRD1
28,DRD2,1-50,Neurotransmitter receptors,,DRD2
29,DRD4,1-50,Neurotransmitter receptors,,DRD4
30,NR3C1,1-50,Neurotransmitter receptors,,NR3C1
31,NPY1R,1-50,Neurotransmitter receptors,,NPY1R
32,OXTR,1-50,Expressed by SST+ neurons to respond to ,,OXTR
33,GRIN2B,1-50,Receptors common for neural plasticity,,GRIN2B
34,GABRA1,1-50,Receptors common for neural plasticity,,GABRA1
35,GRIA1,1-50,Receptors common for neural plasticity,,GRIA1
36,NEDD4,1-50,Marker for excitatory neurons,,NEDD4
37,FBXO2,1-50,Marker for excitatory neurons,,FBXO2
38,mTOR,1-50,Marker for excitatory neurons,,mTOR
39,DDIT4,1-50,Marker for excitatory neurons,,DDIT4
40,TH,1-50,Marker for excitatory neurons,,TH
41,PDGFRA,1-50,OPCs,,PDGFRA
42,GAD1,1-50,"Glutamate Decarboxylase 1, catalyzing production from L-glut. ",,GAD1
43,CHAT,1-50,Neuron enzyme for ACh,,CHAT
44,GRIN2A,1-50,NMDA receptors,,GRIN2A
45,GABRD,1-50,GABA receptors,,GABRD
46,GABRA1,1-50,GABA receptors,,GABRA1
47,TREM2,1-50,microglial marker,,TREM2
48,CSF1R,1-50,microglial marker,,CSF1R
49,IL10,1-50,Microglia function,,IL10
50,EFNA5,50-100,Important pathways for neural plasticity and synaptic homeostasis. ,,EFNA5
51,EPHA5,50-100,Important pathways for neural plasticity and synaptic homeostasis. ,,EPHA5
52,FYN,50-100,Important pathways for neural plasticity and synaptic homeostasis. ,,FYN
53,CARMN,50-100,Endothelial cells: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,CARMN
54,ITIH5,50-100,Endothelial cells: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,ITIH5
55,MECOM,50-100,Endothelial cells: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,MECOM
56,EBF1,50-100,Endothelial cells: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,EBF1
57,VWF,50-100,Endothelial cells: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,VWF
58,LINC02712,50-100,Microglia: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,LINC02712
59,ITGAX,50-100,Microglia: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,ITGAX
60,BLNK,50-100,Microglia: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,BLNK
61,CSF2RA,50-100,Microglia: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,CSF2RA
62,FOLH1,50-100,Oligodendrocytes: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,FOLH1
63,LINC01608,50-100,Oligodendrocytes: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,LINC01608
64,SLC5A11,50-100,Oligodendrocytes: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,SLC5A11
65,OPC,50-100,OPC: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,OPC
66,AC004852.2,50-100,OPC: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,AC004852.2
67,FERMT1,50-100,OPC: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,FERMT1
68,COL9A1,50-100,OPC: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,COL9A1
69,STK32A,50-100,OPC: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,STK32A
70,FGF13,50-100,Excitatory Layer 2 or 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,FGF13
71,SLC12A8,50-100,Excitatory Layer 2 or 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,SLC12A8
72,DCBLD2,50-100,Excitatory Layer 2 or 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,DCBLD2
73,MPC1,50-100,Excitatory Layer 2 or 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,MPC1
74,LINC02296,50-100,Excitatory Layer 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,LINC02296
75,AC008674.1,50-100,Excitatory Layer 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,AC008674.1
76,CLRA3,50-100,Excitatory Layer 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,CLRA3
77,CPHR1,50-100,Excitatory Layer 3: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,CPHR1
78,FBXL16,50-100,Excitatory Layer 3/4/5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,FBXL16
79,MAP1A,50-100,Excitatory Layer 3/4/5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,MAP1A
80,UBB,50-100,Excitatory Layer 3/4/5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,UBB
81,ENC1,50-100,Excitatory Layer 3/4/5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,ENC1
82,TSHZ2,50-100,Excitatory Layer 4 Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,TSHZ2
83,VGF,50-100,Excitatory Layer 4 Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,VGF
84,UBE2E3,50-100,Excitatory Layer 4 Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,UBE2E3
85,APP003066.1,50-100,Excitatory Layer 5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,APP003066.1
86,COL12A1,50-100,Excitatory Layer 5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,COL12A1
87,TRABD2A,50-100,Excitatory Layer 5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,TRABD2A
88,TLL1,50-100,Excitatory Layer 5: Top genes from Huuki-Myers that distinguishes other cell types using scNuc-seq and spatial context. ,,TLL1
89,LINC00343,50-100,Excitatory L5/6,,LINC00343
90,THEMIS,50-100,Excitatory L5/6,,THEMIS
91,AC015943.1,50-100,Excitatory L5/6,,AC015943.1
92,LINC02718,50-100,Excitatory L6: Top genes from Huuki-Myers,,LINC02718
93,MCTP2,50-100,Excitatory L6: Top genes from Huuki-Myers,,MCTP2
94,AC006299.1,50-100,Excitatory L6: Top genes from Huuki-Myers,,AC006299.1
95,DPP4,50-100,Excitatory L6: Top genes from Huuki-Myers,,DPP4
96,MYO3B,50-100,Inhibitory neurons: Top genes from Huuki-Myers,,MYO3B
97,SLC27A6,50-100,Inhibitory neurons: Top genes from Huuki-Myers,,SLC27A6
98,MINAR1,50-100,Inhibitory neurons: Top genes from Huuki-Myers,,MINAR1
99,BTBD11,50-100,Inhibitory neurons: Top genes from Huuki-Myers,,BTBD11
100,FBN2,100-150,Inhibitory neurons: Top genes from Huuki-Myers,,FBN2
101,GRIP2,100-150,Inhibitory neurons: Top genes from Huuki-Myers,,GRIP2
102,COMT,100-150,Enzymes that degrade neurotransmitters,,COMT
103,SLC6A3,100-150,Dopamine transporter,,SLC6A3
104,MAOA,100-150,Breakdown of neurotransmitters,,MAOA
105,CREB1,100-150,Neural activation related genes,,CREB1
106,FOS,100-150,Neural activation related genes,,FOS
107,JUNB,100-150,Neural activation related genes,,JUNB
108,NFAT1,100-150,Neural activation related genes,,NFAT1
109,CRTC1,100-150,Neural activation related genes,,CRTC1
110,CAMK2A,100-150,Neural activation related genes,,CAMK2A
111,CAMK1D,100-150,Neural activation related genes,,CAMK1D
112,APOE4,100-150,"Alzhiemers, microglia. ",,APOE4
113,SHANK3,100-150,Genes altered in ASD,,SHANK3
114,RAC1,100-150,Genes altered in ASD,,RAC1
115,PAK,100-150,Genes altered in ASD,,PAK
116,COFILIN,100-150,Genes altered in ASD,,COFILIN
117,NR2A,100-150,Genes altered in Schizophernia,,NR2A
118,GAD67,100-150,Genes altered in Schizophernia,,GAD67
119,CALM2,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,CALM2
120,SYN1,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,SYN1
121,RAB3A,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,RAB3A
122,RAB4B,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,RAB4B
123,TUBB4,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,TUBB4
124,NR2B,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,NR2B
125,PSD96,100-150,Genes altered in MDD brains also associated with synatic function and reduced spine density in layers II/III of DLPFC,,PSD96
126,cpg15,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,cpg15
127,NTRK2,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,NTRK2
128,HLA-A,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,HLA-A
129,PLK2,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,PLK2
130,Homer1,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,Homer1
131,Arc,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,Arc
132,MIR134,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,MIR134
133,Mecp2,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,Mecp2
134,MEF22c,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,MEF22c
135,CARF,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,CARF
136,HLA-B,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,HLA-B
137,HLA-C,100-150,"Neuronal activity-regulated genes, that alter synaptic function of neurons. ",,HLA-C
138,KIT,100-150,Inhibitory neurons: Top genes from Huuki-Myers,,KIT
139,PLXDC2,100-150,Top DEG from Jupyter of microglia,,PLXDC2
140,DOCK4,100-150,Top DEG from Jupyter of microglia,,DOCK4
141,DOCK8,100-150,Top DEG from Jupyter of microglia,,DOCK8
142,AdGRV1,100-150,Top DEG from jupyter of astrocytes,,AdGRV1
143,SLC1A2,100-150,Top DEG from jupyter of astrocytes,,SLC1A2
144,MSI2,100-150,Top DEG from jupyter of astrocytes,,MSI2
145,GPC5,100-150,Top DEG from jupyter of astrocytes,,GPC5
146,SORCS3,100-150,Caudal Ganglionic derived GABAergic cortical interneurons from Top DEG from Jupyter,,SORCS3
147,ADARB2,100-150,Caudal Ganglionic derived GABAergic cortical interneurons from Top DEG from Jupyter,,ADARB2
148,CXCL14,100-150,Caudal Ganglionic derived GABAergic cortical interneurons from Top DEG from Jupyter,,CXCL14
149,SLC35F4,100-150,Caudal Ganglionic derived GABAergic cortical interneurons from Top DEG from Jupyter,,SLC35F4