pmid
int64
10.6M
40.8M
title
stringlengths
14
606
journal_title
stringlengths
3
239
journal_iso
stringlengths
3
51
volume
stringlengths
1
207
issue
stringclasses
726 values
doi
stringlengths
5
66
language
stringclasses
1 value
pub_date_year
float64
2k
2.03k
pub_date_month
float64
1
12
pub_date_day
float64
1
31
article_date_year
float64
2k
2.03k
article_date_month
float64
1
12
article_date_day
float64
1
31
abstract_text
stringlengths
323
8.65k
keywords
stringlengths
2
1.73k
SJR
float64
0.1
26
H index
float64
0
1.23k
categories
stringlengths
6
264
areas
stringclasses
208 values
sjr_year_source
float64
2k
2.02k
11,165,586
Vaginal fetal fibronectin levels and spontaneous preterm birth in symptomatic women.
Obstetrics and gynecology
Obstet Gynecol
97
2
10.1016/s0029-7844(00)01130-3
eng
2,001
2
null
null
null
null
[OBJECTIVE] To relate vaginal fetal fibronectin levels in women with symptoms of preterm labor to subsequent spontaneous preterm birth. [METHODS] Quantitative fetal fibronectin values were calculated from women who participated in two prospective multicenter trials relating fetal fibronectin to subsequent spontaneous p...
null
1.316
268
Obstetrics and Gynecology
Medicine
2,001
11,164,139
Clinical experience with open renal cryoablation.
Urology
Urology
57
1
10.1016/s0090-4295(00)00878-5
eng
2,001
1
null
null
null
null
[OBJECTIVES] To evaluate the safety and efficacy of open renal cryoablation of small solid renal masses, since the delivery of freezing temperatures has been shown to effectively ablate solid neoplasms of the liver, uterus, and prostate. [METHODS] A total of 29 patients were treated with open renal cryoablation since D...
null
1.399
197
Urology
Medicine
2,001
11,163,046
Emulsification tendency of silicone-phenylsilicone copolymer.
Japanese journal of ophthalmology
Jpn J Ophthalmol
45
1
10.1016/s0021-5155(00)00292-6
eng
2,001
null
null
null
null
null
[PURPOSE] We compared the emulsification tendency of silicone-phenylsilicone copolymer (DPC; 5%-phenylated, specific gravity 0.984) with that of silicone oil (SO; specific gravity 0.966) and fluorosilicone oil (FSO; specific gravity 1.256), all of which are used clinically as intraocular tamponades. [METHODS] We invest...
null
0.496
70
Medicine; Ophthalmology
Medicine
2,001
11,163,044
Quantitative analysis of interleukin-6 in vitreous from patients with proliferative vitreoretinal diseases.
Japanese journal of ophthalmology
Jpn J Ophthalmol
45
1
10.1016/s0021-5155(00)00290-2
eng
2,001
null
null
null
null
null
[PURPOSE] To explore immunological mechanisms in the pathogenesis of proliferative vitreoretinal diseases, we measured the concentration of interleukin-6 in the vitreous body and serum from patients with proliferative diabetic retinopathy (PDR), proliferative vitreoretinopathy (PVR), and premacular fibrosis. To evaluat...
null
0.496
70
Medicine; Ophthalmology
Medicine
2,001
11,162,990
Modified technique of haptic externalization for scleral fixation of dislocated posterior chamber lens implants.
American journal of ophthalmology
Am J Ophthalmol
131
1
10.1016/s0002-9394(00)00650-4
eng
2,001
1
null
null
null
null
[PURPOSE] To describe a modified technique of haptic externalization during repositioning of dislocated posterior chamber lens implants, which facilitates placement of scleral fixation sutures around the haptic for implant stabilization. [METHODS] We describe a technique of repositioning a dislocated posterior chamber ...
null
1.651
221
Ophthalmology
Medicine
2,001
11,162,988
Hypothyroidism and glaucoma. A study of 100 hypothyroid patients.
American journal of ophthalmology
Am J Ophthalmol
131
1
10.1016/s0002-9394(00)00724-8
eng
2,001
1
null
null
null
null
[PURPOSE] To determine whether glaucoma is associated with hypothyroidism, as has previously been suggested. [METHODS] This is a cross-sectional study and a noncomparative interventional case series. One hundred consecutive patients with newly diagnosed hypothyroidism were referred for complete ophthalmologic examinati...
null
1.651
221
Ophthalmology
Medicine
2,001
11,161,917
Clinical events leading to the progression of heart failure: insights from a national database of hospital discharges.
European heart journal
Eur Heart J
22
2
10.1053/euhj.2000.2175
eng
2,001
1
null
null
null
null
[AIMS] To describe the sequence of clinically apparent events causing readmission and antedating death, subsequent to a first-time hospital admission for heart failure, in order to give insights into the natural history and mechanisms of progression of heart failure. [METHODS] A national database of linked hospital dis...
null
null
null
null
null
null
11,161,541
Parenteral nutrition and cyclosporine: do lipids make a difference? A prospective randomized crossover trial.
Clinical nutrition (Edinburgh, Scotland)
Clin Nutr
20
1
10.1054/clnu.2000.0151
eng
2,001
2
null
null
null
null
[AIMS] This prospective, controlled, randomized crossover trial was conducted to assess the effects of parenteral nutrition, with or without lipids, in cyclosporine (CyA) pharmacokinetics. [METHODS] 10 adult patients were randomized on the day of allogeneic bone marrow transplantation to receive isocaloric and isonitro...
null
0.616
183
Critical Care and Intensive Care Medicine; Nutrition and Dietetics
Medicine; Nursing
2,001
11,161,177
Heart motion-adapted MR velocity mapping of blood velocity distribution downstream of aortic valve prostheses: initial experience.
Radiology
Radiology
218
2
10.1148/radiology.218.2.r01ja07548
eng
2,001
2
null
null
null
null
[PURPOSE] To investigate blood flow velocities and shear rates at two distances downstream of an artificial aortic valve in patients. [MATERIALS AND METHODS] Blood velocity was quantified downstream of the valve prosthesis (for replacement after aortic valve stenosis or combined stenosis and regurgitation) in 10 patien...
null
2.485
346
Radiology, Nuclear Medicine and Imaging
Medicine
2,001
11,159,890
Interleukin 10 reduces the incidence of pancreatitis after therapeutic endoscopic retrograde cholangiopancreatography.
Gastroenterology
Gastroenterology
120
2
10.1053/gast.2001.21172
eng
2,001
2
null
null
null
null
[BACKGROUND AND AIMS] Prophylactic administration of interleukin (IL)-10 decreases the severity of experimental pancreatitis. Prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis in humans is a unique model to study the potential role of IL-10 in this setting. [METHODS] In a single-cent...
null
3.203
482
Gastroenterology
Medicine
2,001
11,159,877
Gastric distention correlates with activation of multiple cortical and subcortical regions.
Gastroenterology
Gastroenterology
120
2
10.1053/gast.2001.21201
eng
2,001
2
null
null
null
null
[BACKGROUND AND AIMS] The pathophysiology of functional dyspepsia may involve abnormal processing of visceral stimuli at the level of the central nervous system. There is accumulating evidence that visceral and somatic pain processing in the brain share common neuronal substrates. However, the cerebral loci that proces...
null
3.203
482
Gastroenterology
Medicine
2,001
11,159,059
Estimated risks of radiation-induced fatal cancer from pediatric CT.
AJR. American journal of roentgenology
AJR Am J Roentgenol
176
2
10.2214/ajr.176.2.1760289
eng
2,001
2
null
null
null
null
[OBJECTIVE] In light of the rapidly increasing frequency of pediatric CT examinations, the purpose of our study was to assess the lifetime cancer mortality risks attributable to radiation from pediatric CT. [MATERIALS AND METHODS] Organ doses as a function of age-at-diagnosis were estimated for common CT examinations, ...
null
null
null
null
null
null
11,158,821
Silicone punctal plug extrusion resulting from spontaneous dissection of canalicular mucosa: A clinical and histopathologic report.
Ophthalmology
Ophthalmology
108
2
10.1016/s0161-6420(00)00534-0
eng
2,001
2
null
null
null
null
[PURPOSE] To report on an uncommon, previously unidentified, progressive silicone punctal plug extrusion. [DESIGN] Small, retrospective case series. [PARTICIPANTS] Five cases of punctal plug extrusion were identified among a series of 424 consecutive implantations. Histopathologic analysis was obtained in one case. One...
null
2.409
297
Ophthalmology
Medicine
2,001
11,157,859
Concomitant loss of chromosome 3 and whole arm losses and gains of chromosome 1, 6, or 8 in metastasizing primary uveal melanoma.
Investigative ophthalmology & visual science
Invest Ophthalmol Vis Sci
42
2
null
eng
2,001
2
null
null
null
null
[PURPOSE] To elucidate the genetic differences between metastasizing and nonmetastasizing primary tumors, uveal melanoma samples were screened for DNA copy number alterations by comparative genomic hybridization (CGH). [METHODS] DNA copy number changes were studied on 14 primary uveal melanomas that had not metastasize...
null
null
null
null
null
null
11,157,291
Frequent overcrowding in U.S. emergency departments.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
Acad Emerg Med
8
2
10.1111/j.1553-2712.2001.tb01280.x
eng
2,001
2
null
null
null
null
[OBJECTIVE] To describe the definition, extent, and factors associated with overcrowding in emergency departments (EDs) in the United States as perceived by ED directors. [METHODS] Surveys were mailed to a random sample of EDs in all 50 states. Questions included ED census, frequency, impact, and determination of overc...
null
0.606
148
Emergency Medicine; Medicine
Medicine
2,001
11,157,041
How effective is dose-intensive/myeloablative therapy against Ewing's sarcoma/primitive neuroectodermal tumor metastatic to bone or bone marrow? The Memorial Sloan-Kettering experience and a literature review.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
J Clin Oncol
19
3
10.1200/JCO.2001.19.3.870
eng
2,001
2
1
null
null
null
[PURPOSE] Attempts to improve outcomes of patients with Ewing's sarcoma/primitive neuroectodermal tumor (ES/PNET) metastatic to bone/bone marrow (BM) have focused on chemotherapy dose intensification strategies. We now present results achieved with that approach, as carried out at Memorial Sloan-Kettering Cancer Center...
null
4.111
646
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,156,701
Urinary oxalate, glycolate, glyoxylate, and citrate after acute intravenous administration of glyoxylate in rats.
Molecular urology
Mol Urol
4
4
null
eng
2,000
null
null
null
null
null
[BACKGROUND AND PURPOSE] Urinary oxalate plays an important role in the formation of calcium oxalate renal stones, and approximately 50% to 60% of urinary oxalate is derived from the endogenous metabolism of glyoxylate. Therefore, we measured urinary oxalate, glycolate, glyoxylate, and citrate concentrations after acut...
null
null
null
null
null
null
11,156,538
Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care.
Annals of the rheumatic diseases
Ann Rheum Dis
60
2
10.1136/ard.60.2.91
eng
2,001
2
null
null
null
null
[BACKGROUND] Osteoarthritis is the single most common cause of disability in older adults, and most patients with the condition will be managed in the community and primary care. [AIM] To discuss case definition of knee osteoarthritis for primary care and to summarise the burden of the condition in the community and re...
null
1.054
300
Biochemistry, Genetics and Molecular Biology; Immunology and Allergy; Rheumatology; Immunology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,001
11,156,115
Endoscopic computer-enhanced beating heart coronary artery bypass grafting.
The Annals of thoracic surgery
Ann Thorac Surg
70
6
10.1016/s0003-4975(00)02003-8
eng
2,000
12
null
null
null
null
[BACKGROUND] Telemanipulation systems have enabled coronary revascularization on the arrested heart. The purpose of this study was to develop a technique for computer-enhanced endoscopic coronary artery bypass grafting on the beating heart. [METHODS] The operation was performed using the daVinci telemanipulation system...
null
1.356
230
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,000
11,156,049
Conditions for success in guided bone regeneration: retrospective study on 376 implant sites.
Journal of periodontology
J Periodontol
71
12
10.1902/jop.2000.71.12.1904
eng
2,000
12
null
null
null
null
[BACKGROUND] Used alone or in association with bone, guided bone regeneration is a clinically accepted method to increase the volume of bone during implant placement. Concerns about appropriate surgical techniques and the predictability of the results questions still exist. The aim of this study was to assess the condi...
null
0.952
186
Periodontics
Dentistry
2,000
11,155,020
The change of well-being associated with spa therapy.
Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine
Forsch Komplementarmed Klass Naturheilkd
7
6
10.1159/000057174
eng
2,000
12
null
null
null
null
[OBJECTIVE] The present exploratory study sought to examine the changes of well-being associated with 3 weeks of resort based spa therapy. This is a traditional form of health enhancement incorporating balneotherapy, physical therapies, and health education in an inpatient setting. [PATIENTS AND METHOD] Subjects were s...
null
null
null
null
null
null
11,154,654
Satisfaction, commitment, and psychological well-being among HMO physicians.
The Western journal of medicine
West J Med
174
1
10.1136/ewjm.174.1.13
eng
2,001
1
null
null
null
null
[OBJECTIVE] To identify the factors that predict professional satisfaction, organizational commitment, and burnout among physicians working for health maintenance organizations (HMOs). [METHODS AND PARTICIPANTS] Data came from mail surveys of Kaiser Permanente physicians in the Northwest and Ohio regions. The average r...
null
null
null
null
null
null
11,153,754
Renin angiotensin system-dependent hypertrophy as a contributor to heart failure in hypertensive rats: different characteristics from renin angiotensin system-independent hypertrophy.
Journal of the American College of Cardiology
J Am Coll Cardiol
37
1
10.1016/s0735-1097(00)01064-0
eng
2,001
1
null
null
null
null
[OBJECTIVES] This study aimed to characterize the difference between renin angiotensin system (RAS)-dependent and RAS-independent hypertrophy and their differential contribution to the transition to heart failure. [BACKGROUND] Hypertensive left ventricular (LV) hypertrophy develops with RAS activation in the heart; how...
null
4.039
512
Cardiology and Cardiovascular Medicine
Medicine
2,001
11,153,732
Should diastolic and systolic blood pressure be considered for cardiovascular risk evaluation: a study in middle-aged men and women.
Journal of the American College of Cardiology
J Am Coll Cardiol
37
1
10.1016/s0735-1097(00)01092-5
eng
2,001
1
null
null
null
null
[OBJECTIVES] The goal of this study was to evaluate the role of diastolic blood pressure (DBP) in cardiovascular mortality for different systolic blood pressure (SBP) levels in middle-aged men and women. [BACKGROUND] In middle-aged subjects it is unclear whether DBP, in addition to SBP, should be considered for risk ev...
null
4.039
512
Cardiology and Cardiovascular Medicine
Medicine
2,001
11,153,144
Additive cytotoxic effect of cisplatin and X-irradiation on human glioma cell cultures derived from biopsy-tissue.
Journal of cancer research and clinical oncology
J Cancer Res Clin Oncol
126
12
10.1007/pl00008476
eng
2,000
12
null
null
null
null
[PURPOSE] Investigation of the in vitro cytotoxic effect of X-rays, either alone or combined with cisplatin on early passage cell cultures derived from human glioblastoma multiforme biopsy tissue. [MATERIALS AND METHODS] Fresh tumour specimens from four patients were processed to cell cultures. The U373 glioma cell lin...
null
0.63
114
Medicine; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,000
11,152,362
Influence of smoking, hypertension, and sex on the phenotypic expression of familial intracranial aneurysms in siblings.
Neurosurgery
Neurosurgery
48
1
10.1097/00006123-200101000-00011
eng
2,001
1
null
null
null
null
[OBJECTIVE] To investigate the effects of smoking, hypertension, and sex on the phenotypic expression of familial intracranial aneurysms (FIAs). [METHODS] We retrospectively reviewed the case records of 806 consecutive patients undergoing aneurysm surgery at our institution (1986-1995) and discovered 24 families with a...
null
1.655
229
Neurology; Surgery
Medicine
2,001
11,152,350
Recurrent germinoma in the optic nerve: report of two cases.
Neurosurgery
Neurosurgery
48
1
10.1097/00006123-200101000-00041
eng
2,001
1
null
null
null
null
[OBJECTIVE AND IMPORTANCE] Intracranial germinomas often disseminate via the ventricular and subarachnoid pathways, but seeding to the perioptic arachnoid space is extremely unusual. We report two cases of recurrent germinoma seeding in the optic nerve. [CLINICAL PRESENTATION] Two men with pure germinoma were initially...
null
1.655
229
Neurology; Surgery
Medicine
2,001
11,152,032
Plasma concentrations and pharmacokinetics of bupivacaine with and without adrenaline following caudal anaesthesia in infants.
Acta anaesthesiologica Scandinavica
Acta Anaesthesiol Scand
45
1
10.1034/j.1399-6576.2001.450107.x
eng
2,001
1
null
null
null
null
[BACKGROUND] The aim of this study was to determine whether the use of adrenaline 1/400000 added to 0.25% bupivacaine significantly delays the systemic absorption of the drug from the caudal epidural space in young infants. [METHODS] Fifteen infants less than 5 months of age undergoing minor lower abdominal procedures ...
null
0.931
126
Anesthesiology and Pain Medicine; Medicine
Medicine
2,001
11,151,058
Comparative genomic hybridization: a new tool for reproductive pathology.
Archives of pathology & laboratory medicine
Arch Pathol Lab Med
125
1
10.5858/2001-125-0081-CGH
eng
2,001
1
null
null
null
null
[OBJECTIVE] To demonstrate the effectiveness of comparative genomic hybridization (CGH) for analysis of reproductive pathology specimens in clinical cytogenetics laboratories. [DESIGN] A total of 856 CGH analyses were performed on various placental and fetal tissues derived from 368 specimens of spontaneous abortions a...
null
null
null
null
null
null
11,150,038
Malignant endocrine tumors in patients with MEN 1 disease.
Surgery
Surgery
129
1
10.1067/msy.2001.109500
eng
2,001
1
null
null
null
null
[BACKGROUND] In contrast with multiple endocrine neoplasia type 2, malignancies are of minor importance in multiple endocrine neoplasia type 1 (MEN 1) syndrome. [METHODS] The data for 42 patients with MEN 1 syndrome were evaluated. Twelve patients (29%) had 1 or more associated malignancies: malignant gastrinoma (1 pat...
null
null
null
null
null
null
11,149,989
Exposure to cockroach allergen in the home is associated with incident doctor-diagnosed asthma and recurrent wheezing.
The Journal of allergy and clinical immunology
J Allergy Clin Immunol
107
1
10.1067/mai.2001.111143
eng
2,001
1
null
null
null
null
[BACKGROUND] Indoor inhaled allergens have been repeatedly demonstrated to worsen asthma in sensitized individuals, but their role in incident asthma is more controversial. [OBJECTIVE] We investigated the relationship between exposure to allergens (dust mite, cat, and cockroach) measured in the home and incident doctor...
null
2.024
350
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,001
11,149,099
Three-dimensional (3D) contrast-enhanced power Doppler imaging in Legg-Calvé-Perthes disease.
Pediatric radiology
Pediatr Radiol
30
12
10.1007/s002470000323
eng
2,000
12
null
null
null
null
[BACKGROUND] The revascularization process of the femoral head in Legg-Calvé-Perthes disease has not been well studied on Doppler images. We incorporated two relatively new developments in ultrasound: 3D power Doppler imaging combined with the use of contrast agents. [PATIENTS AND METHODS] We studied two children with ...
null
0.479
104
Pediatrics, Perinatology and Child Health; Radiology, Nuclear Medicine and Imaging
Medicine
2,000
11,148,775
Laparoscopic secondary antireflux procedure after PEG placement in children. Percutaneous endoscopic gastrostomy.
Surgical endoscopy
Surg Endosc
14
12
10.1007/s004640000263
eng
2,000
12
null
null
null
null
[BACKGROUND] This study investigates the feasibility of performing a subsequent laparoscopic antireflux procedure after former placement of a percutaneous endoscopic gastrostomy (PEG). [METHODS] Between 1997 and 1998, five patients with a gastrostomy in place presented with an indication for laparoscopic antireflux pro...
null
1.428
178
Surgery
Medicine
2,000
11,148,556
Reduction in fat intake is not associated with weight loss in most women after breast cancer diagnosis: evidence from a randomized controlled trial.
Cancer
Cancer
91
1
null
eng
2,001
1
1
null
null
null
[BACKGROUND] A reduction in dietary fat intake has been suggested as a method to promote weight loss in women at risk for breast cancer recurrence. [METHODS] Weight change in response to diet intervention was examined in 1010 women who had completed treatment for Stage I, Stage II, or Stage IIIA (American Joint Committ...
null
1.593
349
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,148,012
Kidney cadmium as compared to other markers of cadmium exposure in workers at a secondary metal smelter.
American journal of industrial medicine
Am J Ind Med
39
1
10.1002/1097-0274(200101)39:1<19::aid-ajim2>3.0.co;2-q
eng
2,001
1
null
null
null
null
[BACKGROUND] The aim of the study was to evaluate whether cadmium concentrations in kidney (K-Cd), blood (B-Cd) or urine (U-Cd) could reveal previous occupational cadmium exposure at a metal smelter. [METHODS] The study included 90 smelters and 35 controls (B-Cd and U-Cd determination). In a subgroup (N = 33), K-Cd was...
null
0.922
120
Public Health, Environmental and Occupational Health
Medicine
2,001
11,147,304
Micronucleus frequencies in exfoliated buccal cells in normal mucosa, precancerous lesions and squamous cell carcinoma.
Analytical and quantitative cytology and histology
Anal Quant Cytol Histol
22
6
null
eng
2,000
12
null
null
null
null
[OBJECTIVE] To assess the value of micronuclei in the characterization of precancerous lesions of the oral cavity with reference to their likelihood of progressing to malignant lesions. [STUDY DESIGN] The frequency of micronuclei was determined in exfoliated cells from normal oral mucosa, a preneoplastic condition (leu...
null
null
null
null
null
null
11,147,025
Influence of lung injury on early postoperative survival after lung transplantation.
Annals of transplantation
Ann Transplant
5
3
null
eng
2,000
null
null
null
null
null
[OBJECTIVES] To identify the various risk factors for early (90 day) mortality after lung transplantation and to evaluate the relationship between lung injury and postoperative survival. [METHODS] 152 recipients of single (100) or bilateral (52) lung allografts were evaluated for the presence of postoperative lung inju...
null
0.218
45
Medicine; Transplantation
Medicine
2,000
11,145,808
2000 Volvo Award winner in biomechanical studies: Monitoring in vivo implant loads with a telemeterized internal spinal fixation device.
Spine
Spine (Phila Pa 1976)
25
23
10.1097/00007632-200012010-00004
eng
2,000
12
1
null
null
null
[STUDY DESIGN] Implant loads were measured in 10 patients using telemeterized internal spinal fixation devices. [OBJECTIVE] To determine the postoperative temporal course of implant loads. [SUMMARY OF BACKGROUND DATA] Little information exists regarding the temporal course of loads on internal spinal fixation devices. ...
null
1.319
300
Neurology; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,000
11,145,406
Reduced expression of systemic proinflammatory cytokines after off-pump versus conventional coronary artery bypass grafting.
The Thoracic and cardiovascular surgeon
Thorac Cardiovasc Surg
48
6
10.1055/s-2000-8352
eng
2,000
12
null
null
null
null
[BACKGROUND] Both cardiopulmonary bypass (CPB) and operative trauma are associated with increased expression of proinflammatory cytokines. We assessed the relative contribution of CPB on activation of various proinflammatory cytokines in patients undergoing coronary revascularization by comparing them with patients rec...
null
0.486
60
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,000
11,145,236
Population pharmacokinetics of temozolomide in cancer patients.
Pharmaceutical research
Pharm Res
17
10
10.1023/a:1026403805756
eng
2,000
10
null
null
null
null
[PURPOSE] To evaluate covariate effects on the pharmacokinetics of temozolomide in cancer patients, and to explore the dose-pharmacokinetics-toxicity relationship of temozolomide. [METHODS] Non-linear mixed-effects modeling approach was used to analyze the data from 445 patients enrolled in eleven Phase I and Phase II ...
null
1.067
235
Biotechnology; Organic Chemistry; Pharmaceutical Science; Pharmacology; Pharmacology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,000
11,144,451
Pulmonary tuberculosis in prisons of the ex-USSR state Georgia: results of a nation-wide prevalence survey among sentenced inmates.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
Int J Tuberc Lung Dis
4
12
null
eng
2,000
12
null
null
null
null
[SETTING] The penitentiary system of the ex-USSR state of Georgia. [OBJECTIVES] To measure the prevalence of active pulmonary tuberculosis and drug-resistant disease among prisoners. To identify factors associated with active tuberculosis and multidrug resistance (MDR). [DESIGN] A comprehensive multiphasic screening su...
null
1.022
124
Infectious Diseases; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,000
11,142,602
Probability of helicobacter pylori infection based on IgG levels and other covariates using a mixture model.
Journal of epidemiology and biostatistics
J Epidemiol Biostat
5
5
null
eng
2,000
null
null
null
null
null
[BACKGROUND] To use IgG antibody measurements to detect infection with Helicobacter pylori (H. pylori). one typically defines a cut-off value based on samples of persons presumed to be infected or uninfected. When there are no good 'gold standard' tests to determine infection status, or when laboratory conditions vary,...
null
null
null
null
null
null
11,142,527
Coffee consumption and bladder cancer in nonsmokers: a pooled analysis of case-control studies in European countries.
Cancer causes & control : CCC
Cancer Causes Control
11
10
10.1023/a:1026524014954
eng
2,000
12
null
null
null
null
[BACKGROUND] Coffee consumption has been associated with an excess bladder cancer risk, but results from epidemiological studies are inconsistent. This association has been long debated, in part due to the potential confounding by smoking. We examined the risk associated with coffee consumption in nonsmokers in a poole...
null
null
null
null
null
null
11,142,486
Allogeneic and autologous stem-cell transplantation in advanced Ewing tumors. An update after long-term follow-up from two centers of the European Intergroup study EICESS. Stem-Cell Transplant Programs at Düsseldorf University Medical Center, Germany and St. Anna Kinderspital, Vienna, Austria.
Annals of oncology : official journal of the European Society for Medical Oncology
Ann Oncol
11
11
10.1023/a:1026539908115
eng
2,000
11
null
null
null
null
[BACKGROUND] An update of results from the High Risk Protocol of the Meta-EICESS Study, conducted at the Pediatric Stem-Cell Transplant Centers of Düsseldorf and Vienna. In order to evaluate a possible therapeutic benefit after allogeneic SCT in patients with advanced Ewing tumors (AET), we compared outcome after autol...
null
1.005
311
Hematology; Medicine; Oncology
Medicine
2,000
11,142,429
Premorbid performance IQ deficit in schizophrenia.
Acta psychiatrica Scandinavica
Acta Psychiatr Scand
102
6
10.1034/j.1600-0447.2000.102006414.x
eng
2,000
12
null
null
null
null
[OBJECTIVE] Performance IQ (PIQ) is often lower than verbal IQ (VIQ) in schizophrenic patients. Whether PIQ < VIQ precedes psychotic symptoms in schizophrenia remains uncertain. [METHOD] We investigated premorbid IQ scores in 63 subjects assessed at a child and adolescent psychiatric unit (mean age 13.1 years, SD 3.2),...
null
1.302
174
Psychiatry and Mental Health
Medicine
2,000
11,141,531
Comparative use of biomedical services and traditional healing options by American Indian veterans.
Psychiatric services (Washington, D.C.)
Psychiatr Serv
52
1
10.1176/appi.ps.52.1.68
eng
2,001
1
null
null
null
null
[OBJECTIVE] This study described service use among American Indian veterans, compared use patterns across biomedical care and traditional healing options, and tested whether utilization varied as a function of need or availability. [METHODS] A cross-sectional survey of 621 male combat veterans selected from tribal roll...
null
0.737
174
Medicine; Psychiatry and Mental Health
Medicine
2,001
11,141,230
Immunologic impact and clinical outcomes after surgical exposure to bovine thrombin.
Annals of surgery
Ann Surg
233
1
10.1097/00000658-200101000-00014
eng
2,001
1
null
null
null
null
[OBJECTIVE] To determine prospectively the immunologic response and adverse clinical events in surgical patients exposed to bovine thrombin during cardiac surgical procedures. [SUMMARY BACKGROUND DATA] Topical bovine thrombin is used extensively as a hemostatic agent during cardiovascular surgery. Antibodies developing...
null
3.724
360
Surgery
Medicine
2,001
11,140,328
The effects of d-amphetamine, chlordiazepoxide, alpha-flupenthixol and behavioural manipulations on choice of signalled and unsignalled delayed reinforcement in rats.
Psychopharmacology
Psychopharmacology (Berl)
152
4
10.1007/s002130000536
eng
2,000
11
null
null
null
null
[RATIONALE] Inability to tolerate delays to reward is an important component of impulsive behaviour, and has been suggested to reflect dysfunction of dopamine systems. [OBJECTIVES] The present experiments examined the effects of signalling a delayed, large reward on rats' ability to choose it over a small, immediate re...
null
1.409
218
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,000
11,139,058
Superiority of iodine-123 compared with iodine-131 scanning for thyroid remnants in patients with differentiated thyroid cancer.
Clinical nuclear medicine
Clin Nucl Med
26
1
10.1097/00003072-200101000-00002
eng
2,001
1
null
null
null
null
[PURPOSE] Iodine-123 is a pure gamma emitter and has excellent characteristics for imaging with modern scintillation cameras. The goal of this study was to compare the performance of I-123 and I-131 as imaging agents for whole-body scanning in patients with differentiated thyroid cancer undergoing ablation for thyroid ...
null
0.298
73
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,001
11,138,836
Stability analysis of two linear accommodation and convergence models.
Optometry and vision science : official publication of the American Academy of Optometry
Optom Vis Sci
77
11
10.1097/00006324-200011000-00012
eng
2,000
11
null
null
null
null
[PURPOSE] To perform time domain stability analysis on two widely accepted linear models of accommodation and convergence. [METHODS] For each model, the governing differential equations were used to compute the system matrix. The system matrices were used to calculate the respective trace and determinant from which eig...
null
0.691
121
Ophthalmology; Optometry
Health Professions; Medicine
2,000
11,137,689
Advances in the management of pediatric trauma.
American journal of surgery
Am J Surg
180
5
10.1016/s0002-9610(00)00488-8
eng
2,000
11
null
null
null
null
[BACKGROUND] Numerous important advances have been made in the management of trauma in childhood in prevention, prehospitalization and intrahospital care, postoperative management, and rehabilitation. As with adult trauma care, the development of trauma systems has impacted greatly on morbidity and mortality in injured...
null
1.194
173
Medicine; Surgery
Medicine
2,000
11,137,675
Subliminal visual oddball stimuli evoke a P300 component.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Clin Neurophysiol
112
1
10.1016/s1388-2457(00)00445-4
eng
2,001
1
null
null
null
null
[OBJECTIVE] To provide evidence that a P300 component can be elicited by subliminal stimuli in an oddball paradigm. [METHODS] The words LEFT and RIGHT were presented in a frequent-rare ratio (80-20%), counterbalanced between subjects. Stimuli were presented at the objective detection threshold (d'=0, via unmasked 1 ms ...
null
0.789
230
Neurology; Neurology; Physiology; Sensory Systems
Medicine; Neuroscience
2,001
11,137,637
Influence of pH and storage time on the sorption and solubility behaviour of three composite resin materials.
Journal of dentistry
J Dent
29
1
10.1016/s0300-5712(00)00055-5
eng
2,001
1
null
null
null
null
[OBJECTIVES] The aim of this study was to determine whether pH and time has any influence on the sorption and solubility behaviour of composite resin materials stored in a buffer solution. [METHODS] Three hybrid composite restorative resin materials (Spectrum, Z-100 and ArtGlass) with different matrix structure and fil...
null
0.892
146
Dentistry
Dentistry
2,001
11,137,515
Serum insulin-like growth factor-I (IGF-I) does not correlate positively with isometric strength, fatigue, and quality of life in post-polio syndrome.
Journal of the neurological sciences
J Neurol Sci
182
2
10.1016/s0022-510x(00)00459-7
eng
2,001
1
1
null
null
null
[OBJECTIVES AND BACKGROUND] To determine if serum insulin-like growth factor-I (IGF-I) levels are associated with strength, body mass index (BMI), fatigue, or quality of life in post-poliomyelitis syndrome (PPS). PPS is likely due to a distal disintegration of enlarged post-polio motor units as a result of terminal axo...
null
0.933
158
Neurology; Neurology
Medicine; Neuroscience
2,001
11,137,412
Effectiveness of forced air warming after pediatric cardiac surgery employing hypothermic circulatory arrest without cardiopulmonary bypass.
Journal of clinical anesthesia
J Clin Anesth
12
7
10.1016/s0952-8180(00)00210-5
eng
2,000
11
null
null
null
null
[STUDY OBJECTIVE] To evaluate the effectiveness of forced-air warming compared to radiant warming in pediatric cardiac surgical patients recovering from moderate hypothermia after perfusionless deep hypothermic circulatory arrest. [DESIGN] Prospective unblinded study. SETIING: Teaching hospitals. [PATIENTS] 24 pediatri...
null
0.562
86
Anesthesiology and Pain Medicine
Medicine
2,000
11,136,683
Use of lipid-lowering medications at discharge in patients with acute myocardial infarction: data from the National Registry of Myocardial Infarction 3.
Circulation
Circulation
103
1
10.1161/01.cir.103.1.38
eng
2,001
1
2
null
null
null
[BACKGROUND] The present study aimed to assess use of lipid-lowering medication at discharge in a current national sample of patients hospitalized with acute myocardial infarction and to evaluate factors associated with prescribing patterns. [METHODS AND RESULTS] Demographic, procedural, and discharge medication data w...
null
5.548
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,001
11,136,679
Lethal autoimmune myocarditis in interferon-gamma receptor-deficient mice: enhanced disease severity by impaired inducible nitric oxide synthase induction.
Circulation
Circulation
103
1
10.1161/01.cir.103.1.18
eng
2,001
1
2
null
null
null
[BACKGROUND] Interferon-gamma (IFN-gamma) is an essential cytokine in the regulation of inflammatory responses in autoimmune diseases. Little is known about its role in inflammatory heart disease. [METHODS AND RESULTS] We showed that IFN-gamma receptor-deficient mice (IFN-gammaR(-/-)) on a BALB/c background immunized w...
null
5.548
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,001
11,136,572
CD44 isoform 6 (CD44v6) is a prognostic indicator of the response to neoadjuvant chemotherapy in cervical carcinoma.
Gynecologic oncology
Gynecol Oncol
80
1
10.1006/gyno.2000.6016
eng
2,001
1
null
null
null
null
[OBJECTIVE] Theclinical efficacy of neoadjuvant chemotherapy (NAC) in distinct groups of cervical cancer patients has been well documented, but parameters at the cellular level regulating the different responsiveness to this treatment have not been adequately explored. [METHOD] A series of 21 patients with stage Ib and...
null
0.895
192
Obstetrics and Gynecology; Oncology
Medicine
2,001
11,135,717
Effect of remifentanil on pain and secondary hyperalgesia associated with the heat--capsaicin sensitization model in healthy volunteers.
Anesthesiology
Anesthesiology
94
1
10.1097/00000542-200101000-00008
eng
2,001
1
null
null
null
null
[BACKGROUND] The heat--capsaicin sensitization model was developed as a noninvasive and noninjurious human experimental pain model. The sequential application of moderate intensity thermal and topical chemical stimuli produces stable and long-lasting areas of cutaneous secondary hyperalgesia. The aim of the present stu...
null
null
null
null
null
null
11,135,065
The pck rat: a new model that resembles human autosomal dominant polycystic kidney and liver disease.
Kidney international
Kidney Int
59
1
10.1046/j.1523-1755.2001.00473.x
eng
2,001
1
null
null
null
null
[BACKGROUND] The pck rat is a recently identified model of polycystic kidney disease (PKD) and liver disease (PLD) that developed spontaneously in the rat strain Crj:CD/SD. Its pattern of inheritance is autosomal recessive. [METHODS] To characterize this new model, we studied pck rats derived from F9 breeding pairs fro...
null
null
null
null
null
null
11,135,046
Evaluation of DNA topoisomerase IIalpha expression provides independent prognostic information in non-Hodgkin's lymphomas.
Histopathology
Histopathology
38
1
10.1046/j.1365-2559.2001.01036.x
eng
2,001
1
null
null
null
null
[AIMS] In view of the dual role that DNA topoisomerase IIa (TopoIIa) plays as a cell proliferation marker and as a possible indicator of chemosensitivity, we investigated its expression in non-Hodgkin's lymphomas (NHL) in relation to conventional clinicopathological parameters, cell proliferation (as defined by Ki67 im...
null
0.923
145
Histology; Medicine; Pathology and Forensic Medicine
Medicine
2,001
11,135,041
Expression of CD44 and its variant isoform v3 has no prognostic value in gastric cancer.
Histopathology
Histopathology
38
1
10.1046/j.1365-2559.2001.01038.x
eng
2,001
1
null
null
null
null
[AIMS] To study the controversial role of transmembrane glycoprotein CD44 as a moderator of tumour spread and as a prognostic factor in gastric cancer. [METHODS AND RESULTS] The expression of all CD44 forms and that with exon v3 was assessed in 198 stage I-IV gastric adenocarcinomas using immunohistochemistry. CD44 exp...
null
0.923
145
Histology; Medicine; Pathology and Forensic Medicine
Medicine
2,001
11,135,027
Migraine, as compared to other headaches, is worse during midnight-sun summer than during polar night. A questionnaire study in an Arctic population.
Headache
Headache
40
10
10.1046/j.1526-4610.2000.00149.x
eng
2,000
null
null
null
null
null
[OBJECTIVE] To investigate potential seasonal variation of migraine and other headaches in an Arctic population where light conditions are extreme during both winter and summer. [BACKGROUND] Due to the immense seasonal variation in sunlight, focus on seasonal migraine variation in a population living in an Arctic area ...
null
0.805
146
Neurology; Neurology
Medicine; Neuroscience
2,000
11,134,832
Gonadotropin level abnormalities in women with cyclic mastalgia.
European journal of obstetrics, gynecology, and reproductive biology
Eur J Obstet Gynecol Reprod Biol
94
1
10.1016/s0301-2115(00)00322-5
eng
2,001
1
null
null
null
null
[OBJECTIVES] Women with cyclic mastalgia seem to be at risk of fibrocystic breast disease and/or breast cancer. We studied the relationships between mastalgia and hormone levels throughout the menstrual cycle. [STUDY DESIGN] Ostensibly healthy women were monitored during a sum of 326 cycles. A case-control study compar...
null
null
null
null
null
null
11,133,703
Ultrastructure of the vitreoretinal interface following plasmin assisted vitrectomy.
The British journal of ophthalmology
Br J Ophthalmol
85
1
10.1136/bjo.85.1.6
eng
2,001
1
null
null
null
null
[AIMS] To investigate the ultrastructure of the vitreoretinal interface following plasmin induced posterior vitreous detachment. [METHODS] Plasmin (1 or 2 U/0.1 ml) was injected into the vitreous cavity of 24 eyes of freshly slaughtered pigs. The 24 fellow eyes received calcium-free and magnesium-free PBS and served as...
null
1.26
185
Ophthalmology; Sensory Systems; Cellular and Molecular Neuroscience
Medicine; Neuroscience
2,001
11,133,533
Unenhanced limited CT of the abdomen in the diagnosis of appendicitis in children: comparison with sonography.
AJR. American journal of roentgenology
AJR Am J Roentgenol
176
1
10.2214/ajr.176.1.1760031
eng
2,001
1
null
null
null
null
[OBJECTIVE] The purpose of this investigation is to determine the sensitivity, specificity, and accuracy of unenhanced limited CT of the abdomen in children with suspected appendicitis and compare these results with graded compression sonography. [MATERIALS AND METHODS] Seventy-six children underwent unenhanced limited...
null
null
null
null
null
null
11,133,213
Targeting the slow pathway for atrioventricular nodal reentrant tachycardia: initial results and long-term follow-up in 379 consecutive patients.
European heart journal
Eur Heart J
22
1
10.1053/euhj.2000.2124
eng
2,001
1
null
null
null
null
[OBJECTIVES] This study is designed to examine the immediate and short-term outcomes of patients who have undergone slow pathway ablation/modification for atrioventricular nodal reentrant tachycardia. [BACKGROUND] Targeting the slow pathway has emerged as the superior form of treatment for atrioventricular nodal reentr...
null
null
null
null
null
null
11,133,041
Chromosomal instability induced by heavy ion irradiation.
International journal of radiation biology
Int J Radiat Biol
76
12
10.1080/09553000050201082
eng
2,000
12
null
null
null
null
[PURPOSE] To establish the dose-response relationship for the induction of chromosomal instability in GM10115 cells exposed to high-energy iron ions (1 GeV/nucleon, mean LET 146 keV/microm) and gold ions (11 GeV/nucleon, mean LET 1450 keV/microm). Past work has established that sparsely ionizing X-rays can induce a lon...
NASA Discipline Radiation Health; Non-NASA Center
1.055
104
Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,000
11,132,744
Flumazenil abolishes midazolam-induced increase in the work of nasal breathing.
Canadian journal of anaesthesia = Journal canadien d'anesthesie
Can J Anaesth
47
12
10.1007/BF03019871
eng
2,000
12
null
null
null
null
[PURPOSE] To evaluate the effects of midazolam sedation followed by flumazenil antagonism on the work of nasal breathing in normal humans. [METHODS] We measured minute ventilation through the nasal route, respiratory frequency, nasal resistance (Rn) and the work of nasal breathing under three conditions: awake, during ...
null
null
null
null
null
null
11,132,612
Effect of sildenafil citrate on blood pressure and heart rate in men with erectile dysfunction taking concomitant antihypertensive medication. Sildenafil Study Group.
Journal of hypertension
J Hypertens
18
12
10.1097/00004872-200018120-00022
eng
2,000
12
null
null
null
null
[OBJECTIVES] To assess the acute effect of sildenafil citrate on blood pressure and heart rate in men with erectile dysfunction taking concomitant antihypertensive medication. [DESIGN] Post-hoc subanalysis of five, 12- or 24-week, prospective, randomized, double-blind, placebo-controlled studies. [SETTING] Private-prac...
null
1.333
198
Cardiology and Cardiovascular Medicine; Internal Medicine; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,000
11,132,505
Associations between dental treatment in the primary and permanent dentitions using insurance claims data.
Pediatric dentistry
Pediatr Dent
22
6
null
eng
2,000
null
null
null
null
null
[PURPOSE] The purpose of this study was to assess the associations between dental treatment in the early primary dentition and later treatment in the primary and permanent teeth. [METHODS] Delta Dental Plan of Michigan insurance claims data on 9,886 children who were born in 1990 and were covered by dental insurance fr...
null
null
null
null
null
null
11,131,783
Venous thromboembolism and oral contraceptive use: a methodological study of diagnostic suspicion and referral bias.
The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception
Eur J Contracept Reprod Health Care
5
3
10.1080/13625180008500392
eng
2,000
9
null
null
null
null
[BACKGROUND] In studies of oral contraceptive oral contraceptive use and risk of venous thromboembolism, bias related to heightened diagnostic suspicion and preferential referral of oral contraceptive users has been an issue. The aim of our study was to determine the presence and potential impact of diagnostic suspicio...
null
null
null
null
null
null
11,246,670
Diagnostic value of ferritin and glycosylated ferritin in adult onset Still's disease.
The Journal of rheumatology
J Rheumatol
28
2
null
eng
2,001
2
null
null
null
null
[OBJECTIVE] To determine the usefulness of serum ferritin and glycosylated ferritin (GF) levels in diagnosing adult onset Still's disease (AOSD). [METHODS] We performed a retrospective multicenter study of 205 patients who had ferritin and GF assays in one hospital laboratory. Records of all patients were reviewed, and...
null
1.018
201
Immunology and Allergy; Rheumatology; Immunology
Immunology and Microbiology; Medicine
2,001
11,246,320
Dehydroepiandrosterone decreases mortality rate and improves cellular immune function during polymicrobial sepsis.
Critical care medicine
Crit Care Med
29
2
10.1097/00003246-200102000-00029
eng
2,001
2
null
null
null
null
[OBJECTIVE] Sepsis is associated with a marked depression of cellular immune function. The steroid hormone dehydroepiandrosterone (DHEA) is proposed to have immunoenhancing activities. We, therefore, investigated the effect of DHEA on the mortality rate and cellular immune functions in an experimental model of sepsis. ...
null
0.763
315
Critical Care and Intensive Care Medicine
Medicine
2,001
11,246,310
Risk factors for nosocomial pneumonia in critically ill trauma patients.
Critical care medicine
Crit Care Med
29
2
10.1097/00003246-200102000-00015
eng
2,001
2
null
null
null
null
[OBJECTIVE] To determine risk factors for nosocomial pneumonia in critically ill trauma patients. [DESIGN] Prospective cohort study. [SETTING] The trauma intensive care unit (ICU) of a 1500-bed tertiary-care hospital. [PATIENTS] All critically ill trauma patients (n = 103) admitted consecutively between November 1995 a...
null
0.763
315
Critical Care and Intensive Care Medicine
Medicine
2,001
11,244,266
Pancreatoblastoma: ultrastructural and image DNA cytometric analysis.
Digestive surgery
Dig Surg
18
1
10.1159/000050103
eng
2,001
null
null
null
null
null
[BACKGROUND] Since the first description of a pancreatoblastoma as a malignant pancreatic tumour of childhood in 1957, approximately 60 cases have been reported. We present the symptoms, pathology, and therapy of this rare tumour in a 17-year-old girl. [CASE REPORT] The patient initially presented with upper gastro-int...
null
0.582
80
Gastroenterology; Surgery
Medicine
2,001
11,243,967
Prognostic markers of short-term mortality in AIDS-associated Pneumocystis carinii pneumonia.
Chest
Chest
119
3
10.1378/chest.119.3.844
eng
2,001
3
null
null
null
null
[BACKGROUND] Since 1990, corticosteroids have been recommended as adjunctive therapy for patients with AIDS-associated Pneumocystis carinii pneumonia (PCP) and respiratory failure. We hypothesized that the natural course of AIDS-associated PCP has changed in the era of adjunctive corticosteroid therapy. [OBJECTIVE] To ...
null
0.916
337
Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine
Medicine
2,001
11,242,627
Case report: acute tumour lysis syndrome.
Annals of the Academy of Medicine, Singapore
Ann Acad Med Singap
30
1
null
eng
2,001
1
null
null
null
null
[INTRODUCTION] Acute tumour lysis syndrome (ATLS) is a potentially lethal but preventable complication of oncological treatment. [CLINICAL PICTURE] We report a case of a patient with Burkitt's leukaemia who developed ATLS after treatment with chemotherapy. [TREATMENT] Standard preventive measures using aggressive hydra...
null
0.187
70
Medicine
Medicine
2,001
11,241,430
Maternal multivitamin use and orofacial clefts in offspring.
Teratology
Teratology
63
2
10.1002/1096-9926(200102)63:2<79::AID-TERA1013>3.0.CO;2-3
eng
2,001
2
null
null
null
null
[BACKGROUND] Cleft lip with or without cleft palate (CLP) and cleft palate alone (CP) affect approximately 1 in 1000 infants and 1 in 2,500 infants, respectively. Studies of the relation between orofacial clefts and multivitamins or folic acid have been inconsistent. [METHODS] We used data from a population-based case-...
null
null
null
null
null
null
11,241,129
Molecular mechanisms of aortic wall remodeling in response to hypertension.
Journal of vascular surgery
J Vasc Surg
33
3
10.1067/mva.2001.112231
eng
2,001
3
null
null
null
null
[OBJECTIVE] The molecular basis of vascular response to hypertension is largely unknown. Both cellular and extracellular components are critical. In the current study we tested the hypothesis that there is a balance between vascular cell proliferation and cell death during vessel remodeling in response to hypertension....
null
2.253
225
Cardiology and Cardiovascular Medicine; Surgery
Medicine
2,001
11,240,870
Aspiration and regurgitation prophylaxis in paediatric anaesthesia.
Paediatric anaesthesia
Paediatr Anaesth
11
2
10.1046/j.1460-9592.2001.00630.x
eng
2,001
3
null
null
null
null
[BACKGROUND] Surveys of aspiration prophylaxis in paediatric anaesthesia do not exist. [METHODS] A postal survey was sent out to all UK members of the Association of Paediatric Anaesthetists (APA) to assess current practice. We asked about minimum fasting times for liquids and solids/milk, their routine acid aspiration...
null
0.639
102
Anesthesiology and Pain Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,001
11,240,246
Risk for hemorrhage during the 2-year latency period following gamma knife radiosurgery for arteriovenous malformations.
International journal of radiation oncology, biology, physics
Int J Radiat Oncol Biol Phys
49
4
10.1016/s0360-3016(00)01432-2
eng
2,001
3
15
null
null
null
[PURPOSE] Radiosurgery does not immediately obliterate an arteriovenous malformation (AVM), and the risk for hemorrhage still persists until the AVM is occluded. There is controversy about whether this risk is altered after as compared to before radiosurgery. The aim of this paper is to study this topic further and to ...
null
1.722
286
Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy
2,001
11,239,516
Preliminary report on the effect of xenoperfusion with human blood on cyclosporin A metabolism and cytochrome-P-4503A4-mRNA expression in a pig liver perfusion model.
Clinical biochemistry
Clin Biochem
34
1
10.1016/s0009-9120(00)00203-4
eng
2,001
2
null
null
null
null
[OBJECTIVES] Little is known about the effect of ischemia/reperfusion with xenogenic blood on function and gene expression of CYP3A4, the enzyme largely responsible for the metabolism of the immunosuppressants Cyclosporin A (CsA) and Tacrolimus. [DESIGN AND METHODS] In a pig liver perfusion model, we have compared the ...
null
0.526
130
Medicine; Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,239,513
Hypersialylated macromolecular serum immunoglobulin A1 in type 2 diabetes mellitus.
Clinical biochemistry
Clin Biochem
34
1
10.1016/s0009-9120(00)00192-2
eng
2,001
2
null
null
null
null
[OBJECTIVES] The origin of the elevation of serum immunoglobulin A1 (IgA1) in Type 2 diabetes mellitus (DM) is unsettled. The aim of this study was to address the carbohydrate changes of serum IgA1 from patients with Type 2 diabetes mellitus, as a possible cause of the elevation. [DESIGN AND METHODS] IgA1 was purified ...
null
0.526
130
Medicine; Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,239,298
Supine fall in lung volumes in the assessment of diaphragmatic weakness in neuromuscular disorders.
Archives of physical medicine and rehabilitation
Arch Phys Med Rehabil
82
1
10.1053/apmr.2001.18053
eng
2,001
1
null
null
null
null
[OBJECTIVE] To determine whether diaphragmatic function can be determined by noninvasive respiratory indices in neuromuscular disease. [DESIGN] Vital capacity (VC) and mouth pressure generated during a maximal static inspiratory effort (Pi max) were measured with patients in both sitting and supine positions. [SETTING]...
null
0.983
225
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science
Health Professions; Medicine
2,001
11,239,287
Long-latency auditory-evoked potentials in severe traumatic brain injury.
Archives of physical medicine and rehabilitation
Arch Phys Med Rehabil
82
1
10.1053/apmr.2001.18076
eng
2,001
1
null
null
null
null
[OBJECTIVE] To detect the effects of different deviant stimuli on long-latency auditory-evoked potentials (LLAEPs) in patients with severe impairment of consciousness from traumatic brain injury (TBI) and to define their prognostic value for late functional outcome. [DESIGN] Correlational study on a prospective cohort....
null
0.983
225
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science
Health Professions; Medicine
2,001
11,239,177
Effects of aging on cerebral vasospasm after subarachnoid hemorrhage in rabbits.
Stroke
Stroke
32
3
10.1161/01.str.32.3.620
eng
2,001
3
null
null
null
null
[BACKGROUND AND PURPOSE] The effects of aging on cerebral vasospasm after subarachnoid hemorrhage (SAH) remain to be elucidated. The aim of this study was to clarify age-related differences of vasospasm and of papaverine reactivity in the responses of basilar arteries after SAH in rabbits. [METHODS] Rabbits receiving a...
null
3.022
370
Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience
Medicine; Neuroscience; Nursing
2,001
11,239,040
Short-term efficiency and safety of gene delivery into canine kidneys.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Nephrol Dial Transplant
16
3
10.1093/ndt/16.3.608
eng
2,001
3
null
null
null
null
[BACKGROUND] Gene delivery of biologically active molecules to the kidney may have potential therapeutic applications in renal and cardiovascular diseases. Recombinant adenovirus is one of the most efficient vectors for in vivo gene delivery. However, in vivo toxicity at the site of administration has to be evaluated f...
null
0.742
203
Medicine; Nephrology; Transplantation
Medicine
2,001
11,238,429
Prevalence of HIV infection among former commercial plasma donors in rural eastern China.
Health policy and planning
Health Policy Plan
16
1
10.1093/heapol/16.1.41
eng
2,001
3
null
null
null
null
[BACKGROUND] Sporadic reports of HIV-1 infection among commercial plasma donors in China between 1994 and 1995. [OBJECTIVES] (1) To determine the prevalence of HIV infection among repeat plasma donors; (2) to identify factors associated with HIV infection; and (3) to describe characteristics associated with secondary t...
null
null
null
null
null
null
11,237,939
Green tea or rosemary extract added to foods reduces nonheme-iron absorption.
The American journal of clinical nutrition
Am J Clin Nutr
73
3
10.1093/ajcn/73.3.607
eng
2,001
3
null
null
null
null
[BACKGROUND] Phenolic compounds act as food antioxidants. One of the postulated mechanisms of action is chelation of prooxidant metals, such as iron. Although the antioxidative effect is desirable, this mechanism may impair the utilization of dietary iron. [OBJECTIVE] We sought to determine the effect of phenolic-rich ...
null
2.283
390
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,001
11,237,896
Lower eyelid CO(2) laser rejuvenation: a randomized, prospective clinical study.
Ophthalmology
Ophthalmology
108
3
10.1016/s0161-6420(00)00593-5
eng
2,001
3
null
null
null
null
[PURPOSE] The effect of transconjunctival blepharoplasty alone compared with transconjunctival blepharoplasty and CO(2) laser skin resurfacing on lower lid bulging and wrinkles was examined. [DESIGN] Randomized clinical trial. [PARTICIPANTS] Forty-four subjects, including 13 men and 31 women. [METHODS] Subjects were pr...
null
2.409
297
Ophthalmology
Medicine
2,001
11,235,948
Extent of tumor-brain interface: a new tool to predict evolution of malignant gliomas.
Journal of neurosurgery
J Neurosurg
94
3
10.3171/jns.2001.94.3.0433
eng
2,001
3
null
null
null
null
[OBJECT] Tumor size is one of the features commonly used in oncology to predict disease evolution. However, for most primary brain tumors it is not predictive of outcome. Taking advantage of a gene therapy trial in which recurrences of glioblastoma were targeted with suicide genes, the authors developed a new parameter...
null
1.482
244
Neurology; Surgery
Medicine
2,001
11,235,781
Factors predicting radical treatment after in-hospital conservative management of disk-related sciatica.
Joint bone spine
Joint Bone Spine
68
1
10.1016/s1297-319x(00)00237-2
eng
2,001
2
null
null
null
null
[OBJECTIVE] To determine predictive factors for radical treatment (nucleolysis or surgery) after in-hospital conservative management of low back pain with sciatica (LBPS). [PATIENTS AND METHODS] A standardized form was used to collect data on 134 patients admitted for conservative treatment of LBPS. Subsequent radical ...
null
0.247
95
Rheumatology
Medicine
2,001
11,235,712
Cardiac surgery in the octogenarian: evaluation of risk, cost, and outcome.
The Annals of thoracic surgery
Ann Thorac Surg
71
2
10.1016/s0003-4975(00)02163-9
eng
2,001
2
null
null
null
null
[BACKGROUND] Nationwide, cardiac surgery is being performed more frequently in patients aged 80 years and older. [METHODS] One hundred four octogenarians undergoing a variety of heart-lung procedures were prospectively studied between 1995 and 1998 for comparison with similar patients aged 65 to 75 years (n = 351). [RE...
null
1.484
230
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,001
11,235,706
Clinical results with left axillary to left anterior descending coronary artery bypass.
The Annals of thoracic surgery
Ann Thorac Surg
71
2
10.1016/s0003-4975(00)02460-7
eng
2,001
2
null
null
null
null
[BACKGROUND] The minimally invasive direct coronary artery bypass procedure is not feasible if the left internal mammary artery has been used or has inadequate flow. We have applied a modified minimally invasive direct coronary artery bypass procedure, which uses a graft from the left axillary artery to the left anteri...
null
1.484
230
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,001
11,235,702
Target vessel revascularization without cardiopulmonary bypass in elderly high-risk patients.
The Annals of thoracic surgery
Ann Thorac Surg
71
2
10.1016/s0003-4975(00)02027-0
eng
2,001
2
null
null
null
null
[BACKGROUND] Coronary artery bypass grafting in patients over 75 years is associated with high operative risk. Target vessel revascularization without cardiopulmonary bypass is a promising option for highly selected, older patients. However, the outcome remains uncertain. [METHODS] We investigated 44 patients over 75 y...
null
1.484
230
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,001
11,233,837
Aspects of MR image distortions in radiotherapy treatment planning.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
Strahlenther Onkol
177
2
10.1007/pl00002385
eng
2,001
2
null
null
null
null
[BACKGROUND] Registration of computed tomography (CT) and magnetic resonance (MR) images are commonly performed to define the different target regions used in radiotherapy treatment planning (RTTP). The accuracy of target definition will then depend on the spatial accuracy of the CT and MR data, and on the technique us...
null
0.636
81
Oncology; Radiology, Nuclear Medicine and Imaging
Medicine
2,001
11,233,746
Tumor volume estimation by the percentage carcinoma method in uterine cervix carcinoma.
Analytical and quantitative cytology and histology
Anal Quant Cytol Histol
23
1
null
eng
2,001
2
null
null
null
null
[OBJECTIVE] To assess the capacity of the percentage carcinoma method to predict tumor volume in cervical carcinoma and generate a mathematical equation for calculation of tumor volume. [STUDY DESIGN] Thirteen radical hysterectomy specimens were studied. The actual tumor volume was assessed by stereology. A factor was ...
null
null
null
null
null
null
11,233,400
Postpericardiotomy syndrome: no evidence for a viral etiology.
Cardiology in the young
Cardiol Young
11
1
10.1017/s1047951100012440
eng
2,001
1
null
null
null
null
[BACKGROUND] Postpericardiotomy syndrome has been considered a disorder induced by viral infection. This conclusion is based on serologic criterions, but these may be unreliable following either cardiopulmonary bypass or transfusion therapy. Previous studies have not verified the proposed etiology either by isolation o...
null
0.329
68
Cardiology and Cardiovascular Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,001
11,232,981
Thoracoscopic truncal vagotomy.
The Journal of cardiovascular surgery
J Cardiovasc Surg (Torino)
41
6
null
eng
2,000
12
null
null
null
null
[BACKGROUND] Nowadays the only indications to truncal vagotomy is recurrent ulceration after previous gastric surgery. Truncal vagotomy allows us to obtain a reduction in acid production and to promote ulcer healing, but this technique causes pylorospasm in about 20% of cases and this requires further synchronous or me...
null
0.354
59
Cardiology and Cardiovascular Medicine; Medicine; Surgery
Medicine
2,000