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11,309,230
Heparin protects local skin microcirculation in 210 minutes-long intravital microscopy observations under general anaesthesia.
European journal of medical research
Eur J Med Res
6
4
null
eng
2,001
4
20
null
null
null
[UNLABELLED] Prolonged immobilization of severely ill, bed-ridden patients results in formation of pressure ulcers following inappropriate tissue blood perfusion, and local activation of leukocyte - endothelial cell interactions (L/EC). Various treatment modalities were implemented to improve local microcirculation wit...
null
0.28
70
Medicine
Medicine
2,001
11,308,436
Use of the CONSORT statement and quality of reports of randomized trials: a comparative before-and-after evaluation.
JAMA
JAMA
285
15
10.1001/jama.285.15.1992
eng
2,001
4
18
null
null
null
[CONTEXT] The Consolidated Standards for Reporting of Trials (CONSORT) statement was developed to help improve the quality of reports of randomized controlled trials (RCTs). To date, a paucity of data exists regarding whether it has achieved this goal. [OBJECTIVE] To determine whether use of the CONSORT statement is as...
null
null
null
null
null
null
11,308,235
Penetrating neck injuries: analysis of experience from a Canadian trauma centre.
Canadian journal of surgery. Journal canadien de chirurgie
Can J Surg
44
2
null
eng
2,001
4
null
null
null
null
[OBJECTIVE] To study the demographics and treatment outcome of penetrating neck injuries presenting to a major trauma centre in order to develop a treatment protocol. [DESIGN] A case review. [SETTING] A trauma centre at a tertiary care institution. [PATIENTS] One hundred and thirty consecutive patients who had 134 neck...
null
null
null
null
null
null
11,308,175
Opening of mitochondrial ATP-sensitive potassium channels enhances cardioplegic protection.
The Annals of thoracic surgery
Ann Thorac Surg
71
4
10.1016/s0003-4975(00)02667-9
eng
2,001
4
null
null
null
null
[BACKGROUND] Mitochondrial and sarcolemmal ATP-sensitive potassium channels have been implicated in cardioprotection; however, the role of these channels in magnesium-supplemented potassium (K/Mg) cardioplegia during ischemia or reperfusion is unknown. [METHODS] Rabbit hearts (n = 76) were used for Langendorff perfusio...
null
1.484
230
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,001
11,308,144
Preoperative chemotherapy for lung cancer does not increase surgical morbidity.
The Annals of thoracic surgery
Ann Thorac Surg
71
4
10.1016/s0003-4975(01)02406-7
eng
2,001
4
null
null
null
null
[BACKGROUND] Preoperative chemotherapy (C+S) for non-small cell lung cancer (NSCLC) has increased in an attempt to improve survival. Patients receiving C+S potentially may have an increase in postoperative morbidity and mortality compared with surgery alone (S). We reviewed our experience with C+S and S in a tertiary r...
null
1.484
230
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,001
11,307,450
The preparation of periapical lesions for flow cytometry.
International endodontic journal
Int Endod J
33
2
10.1046/j.1365-2591.2000.00294.x
eng
2,000
3
null
null
null
null
[AIM] To devise an optimal protocol and to analyse the leucocyte composition of periapical (PA) lesions by flow cytometry. [METHODOLOGY] PA lesions were mechanically agitated, with and without proteolysis. This was with either 0.2% collagenase alone, or in combination with 0.02% DNA-ase in serial incubations until all ...
null
1.089
157
Dentistry
Dentistry
2,000
11,307,445
Cleaning efficacy of two apical preparation regimens following shaping with hand files of greater taper.
International endodontic journal
Int Endod J
33
3
10.1046/j.1365-2591.2000.00290.x
eng
2,000
5
null
null
null
null
[AIM] The aim of this investigation was to assess canal cleaning following shaping with hand files of greater taper. [METHODOLOGY] Thirty mesial canals and 30 distal canals in mandibular molars were prepared with .08 and .10 hand files of greater taper, respectively. Following initial preparation, 0.02 instruments were...
null
1.089
157
Dentistry
Dentistry
2,000
11,306,887
Unenhanced helical computed tomography in the evaluation of acute flank pain.
European urology
Eur Urol
39
4
10.1159/000052486
eng
2,001
4
null
null
null
null
[OBJECTIVE] The diagnostic value of unenhanced helical computed tomography (CT) for the evaluation of acute flank pain is investigated in a prospective study. [PATIENTS AND METHODS] In 125 patients aged 18-86 years, we performed unenhanced helical CT in addition to abdominal plain film, abdominal ultrasound and urinaly...
null
1.106
274
Urology
Medicine
2,001
11,306,876
The progression of benign prostatic hyperplasia: examining the evidence and determining the risk.
European urology
Eur Urol
39
4
10.1159/000052475
eng
2,001
4
null
null
null
null
[BACKGROUND] Benign prostatic hyperplasia (BPH) is often associated with enlargement of the prostate gland, lower urinary tract symptoms, decreased urinary flow and a reduced quality of life. Furthermore, if the symptoms associated with BPH are left untreated, serious complications, such as acute urinary retention, may...
null
1.106
274
Urology
Medicine
2,001
11,306,402
Determinants of continence in the bladder exstrophy population: predictors of success?
Urology
Urology
57
4
10.1016/s0090-4295(00)01102-x
eng
2,001
4
null
null
null
null
[OBJECTIVES] To delineate factors that may predict eventual urinary continence after bladder neck reconstruction (BNR) in the bladder exstrophy population. [METHODS] The records of 65 patients who underwent all phases of bladder exstrophy reconstruction at our institution between 1975 and 1997 with greater than 1-year ...
null
1.399
197
Urology
Medicine
2,001
11,305,848
Life events and depression in a community sample of siblings.
Psychological medicine
Psychol Med
31
3
10.1017/s0033291701003361
eng
2,001
4
null
null
null
null
[BACKGROUND] The overall aim of the GENESiS project is to identify quantitative trait loci (QTLs) for anxiety/depression, and to examine the interaction between these loci and psychosocial adversity. Here we present life-events data with the aim of clarifying: (i) the aetiology of life events as inferred from sibling c...
null
2.286
251
Applied Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,001
11,305,834
Postpartum postural headache due to superior sagittal sinus thrombosis mistaken for spontaneous intracranial hypotension.
Canadian journal of anaesthesia = Journal canadien d'anesthesie
Can J Anaesth
48
3
10.1007/BF03019763
eng
2,001
3
null
null
null
null
[PURPOSE] To describe a case of superior sagittal sinus thrombosis in the puerperal period and the difficulties encountered in the diagnosis and management. [CLINICAL FEATURES] A 29-yr-old multiparous woman presented with a postural headache four weeks after a normal pregnancy and vigorous delivery. Initial presentatio...
null
null
null
null
null
null
11,305,286
Incidence of keratoconus in subjects with vernal keratoconjunctivitis: a videokeratographic study.
Ophthalmology
Ophthalmology
108
4
10.1016/s0161-6420(00)00664-3
eng
2,001
4
null
null
null
null
[PURPOSE] To detect the incidence of keratoconus by videography in patients with vernal keratoconjunctivitis (VKC) and to evaluate the clinical characteristics of VKC associated with keratoconus. [DESIGN] a prospective, cross-sectional (prevalence) study. [PARTICIPANTS] Eighty-two consecutive subjects with the diagnosi...
null
2.409
297
Ophthalmology
Medicine
2,001
11,305,263
High phosphorus intake only slightly affects serum minerals, urinary pyridinium crosslinks and renal function in young women.
European journal of clinical nutrition
Eur J Clin Nutr
55
3
10.1038/sj.ejcn.1601131
eng
2,001
3
null
null
null
null
[OBJECTIVE] Assessment of the physiological effects of a diet rich in phosphorus in young women. [DESIGN] Control period I--commercial basic diet containing 1700 mg P and 1500 mg Ca/day for 4 weeks. Supplementation period--a 6 week high-phosphorus period of 3008 mg P and 1995 mg Ca/day. Control period II--4 weeks washo...
null
0.942
187
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,001
11,304,869
Persistent large choroid plexus cyst. A case report.
The Journal of reproductive medicine
J Reprod Med
46
3
null
eng
2,001
3
null
null
null
null
[BACKGROUND] Prenatally diagnosed choroid plexus cysts regress or resolve spontaneously during pregnancy. A persistent large choroid plexus cyst with a prenatal diagnosis has not been reported previously. [CASE] A 28-year-old, healthy primigravida was referred to our department at 32 weeks' gestation for a suspected fe...
null
null
null
null
null
null
11,304,814
Thickness of the retinal nerve fiber layer in amblyopic and normal eyes: a scanning laser polarimetry study.
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
J AAPOS
5
2
10.1067/mpa.2001.112678
eng
2,001
4
null
null
null
null
[PURPOSE] To compare scanning laser polarimeter (GDx, Laser Diagnostic Technologies, San Diego, Calif) measurements of the peripapillar retinal nerve fiber layer in amblyopic and normal eyes. [METHODS] Scanning laser polarimetry was performed on 21 patients with unilateral strabismic amblyopia who had an absence of neu...
null
0.603
82
Pediatrics, Perinatology and Child Health; Ophthalmology
Medicine
2,001
11,303,155
Start with a subjective assessment of skin temperature to identify hypoperfusion in intensive care unit patients.
The Journal of trauma
J Trauma
50
4
10.1097/00005373-200104000-00005
eng
2,001
4
null
null
null
null
[OBJECTIVE] To determine whether physical examination alone or in combination with biochemical markers can accurately diagnose hypoperfusion. [METHODS] Data from 264 consecutive surgical intensive care unit patients were collected by two intensivists and included extremity temperature, vital signs, arterial lactate, ar...
null
null
null
null
null
null
11,303,082
Research priorities in occupational health in Italy.
Occupational and environmental medicine
Occup Environ Med
58
5
10.1136/oem.58.5.325
eng
2,001
5
null
null
null
null
[OBJECTIVE] To find a broad consensus on research priorities and strategies in the field of occupational health and safety in Italy. [METHODS] A two phase questionnaire survey was based on the Delphi technique previously described in other reports. 310 Occupational safety and health specialists (from universities and l...
null
1.375
167
Public Health, Environmental and Occupational Health
Medicine
2,001
11,303,079
Leukaemia mortality in relation to magnetic field exposure: findings from a study of United Kingdom electricity generation and transmission workers, 1973-97.
Occupational and environmental medicine
Occup Environ Med
58
5
10.1136/oem.58.5.307
eng
2,001
5
null
null
null
null
[OBJECTIVE] To investigate whether risks of leukaemia are related to occupational exposure to magnetic fields. [METHODS] The mortality experienced by a cohort of 83 997 employees of the former Central Electricity Generating Board of England and Wales was investigated for the period 1973-97. All employees were employed ...
null
1.375
167
Public Health, Environmental and Occupational Health
Medicine
2,001
11,302,870
Polymorphisms of the mannose binding lectin gene in patients with Sjögren's syndrome.
Annals of the rheumatic diseases
Ann Rheum Dis
60
5
10.1136/ard.60.5.483
eng
2,001
5
null
null
null
null
[OBJECTIVE] To investigate polymorphisms of both codon 54 allele and promoter variants of the mannose binding lectin (MBL) gene in patients with primary Sjögren's syndrome (SS). [METHODS] Polymorphisms of codon 54 allele and promoter variants of the MBL gene in 104 patients with SS and 143 healthy controls were determi...
null
1.054
300
Biochemistry, Genetics and Molecular Biology; Immunology and Allergy; Rheumatology; Immunology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,001
11,302,621
Surgery in adults with tethered cord syndrome: outcome study with independent clinical review.
Journal of neurosurgery
J Neurosurg
94
2 Suppl
10.3171/spi.2001.94.2.0205
eng
2,001
4
null
null
null
null
[OBJECT] The authors conducted a study to evaluate the risks and short-term benefits of surgical treatment for tethered cord syndrome (TCS) in patients older than 18 years of age. [METHODS] The authors studied a series of 57 consecutive adult patients with TCS of varying origins. Patients were examined by the same neur...
null
1.482
244
Neurology; Surgery
Medicine
2,001
11,301,931
An audit of the theoretical basis of education during dietetic consultations with diabetic patients.
Journal of human nutrition and dietetics : the official journal of the British Dietetic Association
J Hum Nutr Diet
14
1
10.1046/j.1365-277x.2001.00269.x
eng
2,001
2
null
null
null
null
[BACKGROUND] This article describes my attempts to reflect my current practice. It was conducted in order to determine which of three educational models, Empowerment, Motivational Interviewing and Helping People to Change, were being used during a diabetic dietetic consultation. [METHOD] Analysis of interviews with 15 ...
null
0.268
90
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,001
11,301,927
Home tube feeding: an integrated multidisciplinary approach.
Journal of human nutrition and dietetics : the official journal of the British Dietetic Association
J Hum Nutr Diet
14
1
10.1046/j.1365-277x.2001.00266.x
eng
2,001
2
null
null
null
null
[BACKGROUND] Long-term enteral tube feeding is increasingly required by patients in the community setting. A previous study of 50 adults on home enteral tube feeding in the Dublin area found that some experienced logistical problems and many individuals did not choose to seek advice from their GP regarding their tube f...
null
0.268
90
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,001
11,301,106
Mitochondrial disruption and limited apoptosis of erythroblasts are associated with high risk myelodysplasia. An ultrastructural analysis.
Leukemia research
Leuk Res
25
5
10.1016/s0145-2126(00)00151-x
eng
2,001
5
null
null
null
null
[AIMS] To investigate the ultrastructural characteristics of erythroblasts in myelodysplasia (MDS) which might be of additional importance in understanding its pathogenesis. [METHODS AND RESULTS] 22 patients were classified according to FAB (French-American-British classification), IPSS (international prognostic score ...
null
0.539
98
Hematology; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,300,462
Modulation of oxidative stress by a selective inhibition of angiotensin II type 1 receptors in MI rats.
Journal of the American College of Cardiology
J Am Coll Cardiol
37
5
10.1016/s0735-1097(01)01126-3
eng
2,001
4
null
null
null
null
[OBJECTIVES] To examine whether blocking of the renin-angiotensin system (RAS) at the angiotensin II type 1 (AT1) receptor site is accompanied by changes in the oxidative stress parameters. [BACKGROUND] Congestive heart failure in rats after myocardial infarction (MI) has been shown to correlate with a decrease in anti...
null
4.039
512
Cardiology and Cardiovascular Medicine
Medicine
2,001
11,300,431
Angiography of potential cardiac donors.
Journal of the American College of Cardiology
J Am Coll Cardiol
37
5
10.1016/s0735-1097(01)01134-2
eng
2,001
4
null
null
null
null
[OBJECTIVES] This retrospective review of organ donor records was designed to evaluate the practice of donor angiography in one organ procurement organization and determine the outcomes of angiography and its impact on the timing of the organ donation process. [BACKGROUND] Concerns about transmission of atherosclerosis...
null
4.039
512
Cardiology and Cardiovascular Medicine
Medicine
2,001
11,300,389
Ropivacaine 1 mg x ml(-1) does not decrease the need for epidural fentanyl after hip replacement surgery.
Acta anaesthesiologica Scandinavica
Acta Anaesthesiol Scand
45
4
10.1034/j.1399-6576.2001.045004489.x
eng
2,001
4
null
null
null
null
[BACKGROUND] Ropivacaine is a new long-acting local anesthetic. Laboratory trials have demonstrated a synergistic analgesic effect between intrathecal opioids and local anesthetics. We tested the hypothesis that addition of ropivacaine 1 mg x ml(-1) to epidural fentanyl (10 microg x ml(-1)) postoperatively decreases th...
null
0.931
126
Anesthesiology and Pain Medicine; Medicine
Medicine
2,001
11,300,332
Pre-clinical and clinical study of QC12, a water-soluble, pro-drug of quercetin.
Annals of oncology : official journal of the European Society for Medical Oncology
Ann Oncol
12
2
10.1023/a:1008372017097
eng
2,001
2
null
null
null
null
[BACKGROUND] Quercetin is a naturally occurring flavonoid with many biological activities including inhibition of a number of tyrosine kinases. A phase I, dose-escalation trial of quercetin defined the maximum tolerated dose (MTD) as 1700 mg/m2 three weekly, but the vehicle, dimethyl sulphoxide (DMSO) is unsuitable for...
null
1.098
311
Hematology; Medicine; Oncology
Medicine
2,001
11,300,277
Local vestibular blood flow and systemic vascular responses to natural vestibular stimulation in the Mongolian gerbil.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Otol Neurotol
22
2
10.1097/00129492-200103000-00022
eng
2,001
3
null
null
null
null
[HYPOTHESIS] Natural stimulation of the vestibular end organs will produce alterations in the local vestibular microvascular blood flow. [BACKGROUND] The vestibular and cardiovascular systems require a coordinated interaction to maintain organ perfusion during rapid positional and postural changes. However, the detaile...
null
null
null
null
null
null
11,298,547
Cytokine gene polymorphisms in psoriasis.
The British journal of dermatology
Br J Dermatol
144
4
10.1046/j.1365-2133.2001.04143.x
eng
2,001
4
null
null
null
null
[BACKGROUND] Cytokine production is under genetic control, and certain allelic variants of cytokine genes are associated with higher or lower cytokine production in vitro and in vivo. Psoriasis is associated with an overexpression in the involved skin of T-helper cell type 1 (Th1) cytokines, e.g. interferon (IFN) -gamm...
null
1.142
214
Dermatology; Medicine
Medicine
2,001
11,298,234
Expression of a modified Neocallimastix patriciarum xylanase in Butyrivibrio fibrisolvens digests more fibre but cannot effectively compete with highly fibrolytic bacteria in the rumen.
Journal of applied microbiology
J Appl Microbiol
90
3
10.1046/j.1365-2672.2001.01257.x
eng
2,001
3
null
null
null
null
[AIMS] This study investigated the competitive abilities of two Neocallimastix patriciarum-derived xylanases constructs in Butyrivibrio fibrisolvens H17c (xynA and pUMSX) and their ability to compete in vivo. [METHODS AND RESULTS] The digestibility of neutral detergent fibre (NDF) increased during co-culture of xynA or...
null
0.951
195
Applied Microbiology and Biotechnology; Biotechnology; Medicine
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,001
11,298,227
Metabolic response of biofilm to shear stress in fixed-film culture.
Journal of applied microbiology
J Appl Microbiol
90
3
10.1046/j.1365-2672.2001.01244.x
eng
2,001
3
null
null
null
null
[AIMS] In a biofilm reactor, detachment force resulting from hydraulic shear is a major factor that determines the formation and structure of steady state biofilm. The metabolic response of biofilm to change in shear stress was therefore investigated. [METHODS AND RESULTS] A conventional annular reactor made of PVC was...
null
0.951
195
Applied Microbiology and Biotechnology; Biotechnology; Medicine
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,001
11,298,049
Endopyelotomy in the symptomatic older child.
BJU international
BJU Int
87
6
10.1046/j.1464-410x.2001.00098.x
eng
2,001
4
null
null
null
null
[OBJECTIVE] To evaluate the results of endopyelotomy in children, an established method in adult practice as a treatment for pelvi-ureteric junction (PUJ) obstruction. [PATIENTS AND METHODS] Endopyelotomies undertaken between 1992 and 1999 by one surgeon in an established endourology unit were reviewed retrospectively....
null
0.701
174
Urology
Medicine
2,001
11,298,046
Laparoscopic partial upper pole nephrectomy in infants and children.
BJU international
BJU Int
87
6
10.1046/j.1464-410x.2001.00131.x
eng
2,001
4
null
null
null
null
[OBJECTIVE] To retrospectively review 5 years' experience of transperitoneal laparoscopic partial nephrectomy (LPN) in infants and children. [PATIENTS AND METHODS] Between January 1995 and December 1999, 14 upper-pole partial nephrectomies (seven right and seven left) were undertaken in 13 children (mean age 3.8 years,...
null
0.701
174
Urology
Medicine
2,001
11,297,085
Short-term follow-up of the juvenile rheumatoid knee with fat-saturated 3D MRI.
Pediatric radiology
Pediatr Radiol
31
3
10.1007/s002470000371
eng
2,001
3
null
null
null
null
[OBJECTIVE] To determine the correlation between clinical status and 3D, fat-saturated contrast-enhanced MRI findings in assessing the response to treatment in patients with knee-joint involvement from juvenile rheumatoid arthritis (JRA). [MATERIALS AND METHODS] Synovial hypertrophy, effusion, cartilage and epiphyseal ...
null
0.514
104
Pediatrics, Perinatology and Child Health; Radiology, Nuclear Medicine and Imaging
Medicine
2,001
11,296,964
Fibromyalgia and chronic widespread pain in patients with inflammatory bowel disease: a cross sectional population survey.
The Journal of rheumatology
J Rheumatol
28
3
null
eng
2,001
3
null
null
null
null
[OBJECTIVE] To assess the prevalence of fibromyalgia (FM) and chronic widespread pain (CWP) in a population based cohort of patients with inflammatory bowel disease (IBD). [METHODS] Patients in a prospective survey on newly diagnosed IBD were, 5 years after study entry, invited to a clinical examination including the i...
null
1.018
201
Immunology and Allergy; Rheumatology; Immunology
Immunology and Microbiology; Medicine
2,001
11,296,780
The pattern of elderly abuse presenting to an emergency department.
Singapore medical journal
Singapore Med J
41
12
null
eng
2,000
12
null
null
null
null
[AIM] To determine the pattern and frequency of elder abuse presenting to an urban Emergency unit in Singapore. [METHOD] The survey was conducted from May 1994 to December 1997. The patients consisted of adults who were 65 years or older who presented to the Emergency Department with non-accidental trauma or complained...
null
0.155
74
Medicine
Medicine
2,000
11,295,896
Centralization phenomenon as a prognostic factor for chronic low back pain and disability.
Spine
Spine (Phila Pa 1976)
26
7
10.1097/00007632-200104010-00012
eng
2,001
4
1
null
null
null
[STUDY DESIGN] Two hundred twenty-three consecutive adults with acute low back pain with or without referred spinal symptoms were treated conservatively and followed prospectively for 1 year. [OBJECTIVES] To investigate the predictive value of centralization phenomenon (CP) with psychosocial variables previously identi...
null
1.078
300
Neurology; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,001
11,295,756
830-nm irradiation increases the wound tensile strength in a diabetic murine model.
Lasers in surgery and medicine
Lasers Surg Med
28
3
10.1002/lsm.1042
eng
2,001
null
null
null
null
null
[BACKGROUND AND OBJECTIVE] The purpose of this study was to investigate the effects of low-power laser irradiation on wound healing in genetic diabetes. [STUDY DESIGN/MATERIALS AND METHODS] Female C57BL/Ksj/db/db mice received 2 dorsal 1 cm full-thickness incisions and laser irradiation (830 nm, 79 mW/cm(2), 5.0 J/cm(2...
null
0.748
130
Dermatology; Surgery
Medicine
2,001
11,290,983
Laparoscopic management of a posterior mediastinal tumor mimicking an adrenal neoplasm.
Surgical endoscopy
Surg Endosc
14
7
10.1007/s004640000097
eng
2,000
7
null
2,000
4
17
[BACKGROUND] Rarely, a posterior mediastinal mass may mimic an adrenal tumor on preoperative computed tomography scan. The intraoperative discovery that a mass thought to be associated with the adrenal gland actually is above the diaphragm in the posteroinferior mediastinum poses a challenge for the laparoscopic surgeo...
null
1.428
178
Surgery
Medicine
2,000
11,290,886
Lymphoscintigraphic sentinel node imaging and gamma probe detection in breast cancer with Tc-99m nanocolloidal albumin: results of an optimized protocol.
Clinical nuclear medicine
Clin Nucl Med
26
4
10.1097/00003072-200104000-00002
eng
2,001
4
null
null
null
null
[PURPOSE] The purpose of this study was to aid in the standardization of lymphoscintigraphy for detecting the sentinel node (SN) in breast cancer using Tc-99m-labeled nanocolloidal albumin. [MATERIALS AND METHODS] One hundred twenty-three women with proved breast cancer were enrolled. Four injections of 10 to 15 MBq (0...
null
0.298
73
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,001
11,288,812
L-Arginine improves endothelial function in renal artery of hypertensive Dahl rats.
Journal of hypertension
J Hypertens
19
3
10.1097/00004872-200103000-00010
eng
2,001
3
null
null
null
null
[OBJECTIVES] To clarify whether endothelium-derived contracting factor (EDCF) is developed in renal artery of hypertensive Dahl rats and whether prolonged oral L-arginine treatments prevent development of EDCF and hypertension. [DESIGN] The effect of prolonged salt treatment with or without L-arginine on the renal arte...
null
1.649
198
Cardiology and Cardiovascular Medicine; Internal Medicine; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,288,760
Cortisol-secreting adrenal adenomas express 11beta-hydroxysteroid dehydrogenase type-2 gene yet possess low 11beta-HSD2 activity.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research
J Investig Med
49
2
10.2310/6650.2001.34046
eng
2,001
3
null
null
null
null
[BACKGROUND] 11beta-hydroxysteroid dehydrogenase Type-2 (11beta-HSD2) is an unidirectional enzyme that catalyzes the conversion of glucocorticoid hormones cortisol and corticosterone (B) into their corresponding inactive forms, cortisone, and 11-dehydrocorticosterone (DH-B). We have provided evidence that 11beta-HSD2 i...
null
null
null
null
null
null
11,287,689
The prevalence of Chlamydia trachomatis infection in male undergraduates: a postal survey.
Sexually transmitted infections
Sex Transm Infect
77
2
10.1136/sti.77.2.111
eng
2,001
4
null
null
null
null
[OBJECTIVES] To determine the prevalence of Chlamydia trachomatis infection in male undergraduates and to investigate whether prevalence increases with time spent at university. To investigate the feasibility of screening men for C trachomatis by self sampling and posting of urine specimens. [METHODS] The study design ...
null
0.898
115
Dermatology; Infectious Diseases
Medicine
2,001
11,287,041
Histocompatibility leukocyte antigen-G is not expressed by endometriosis or endometrial tissue.
Fertility and sterility
Fertil Steril
75
4
10.1016/s0015-0282(00)01791-x
eng
2,001
4
null
null
null
null
[OBJECTIVE] The immunological mechanisms that support persistence and proliferation of ectopic endometrial implants within the peritoneal cavity of women with endometriosis are unknown. Inhibition of natural killer (NK) and cytotoxic T-cell function has been proposed as a mechanism. We tested the hypothesis that expres...
null
1.354
252
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,001
11,287,039
Gross and histologic characteristics of laparoscopic injuries with four different energy sources.
Fertility and sterility
Fertil Steril
75
4
10.1016/s0015-0282(00)01785-4
eng
2,001
4
null
null
null
null
[OBJECTIVE] To compare the gross and histologic effects of bipolar and monopolar cautery, ultrasonic scalpel, and CO(2) laser on porcine ureter, bladder, and rectum. [DESIGN] Experimental prospective study. [SETTING] Cleveland Clinic Foundation Animal Research Laboratory, Cleveland, Ohio. [ANIMAL(S)] Nonpregnant adult ...
null
1.354
252
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,001
11,287,017
Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation, in fertile and infertile men.
Fertility and sterility
Fertil Steril
75
4
10.1016/s0015-0282(00)01796-9
eng
2,001
4
null
null
null
null
[OBJECTIVE] To evaluate two different assays of human sperm DNA integrity, DNA denaturation (DD) and DNA fragmentation (DF), and to correlate these with standard semen parameters. [DESIGN] Prospective, observational study. [SETTING] University infertility clinic. [PATIENT(S)] Forty consecutive semen samples from 33 non...
null
1.354
252
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,001
11,286,838
Apoptosis, proliferation and p53, cyclin D1, and retinoblastoma gene expression in relation to radiation response in transitional cell carcinoma of the bladder.
International journal of radiation oncology, biology, physics
Int J Radiat Oncol Biol Phys
49
5
10.1016/s0360-3016(00)01503-0
eng
2,001
4
1
null
null
null
[PURPOSE] To determine whether the apoptotic index, the Ki67 index, and the expression of the p53, cyclin D1, and retinoblastoma genes correlate with local control, overall survival, and time to distant metastases in invasive bladder cancer treated with external beam radiation. [METHODS AND MATERIALS] Paraffin-embedded...
null
1.722
286
Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy
2,001
11,286,580
Spinal ultrasound in cloacal exstrophy.
Clinical radiology
Clin Radiol
56
4
10.1053/crad.2000.0648
eng
2,001
4
null
null
null
null
[AIM] To assess the diagnostic value of spinal ultrasound in cloacal exstrophy, a caudal malformation which is associated with spinal dysraphism, and to assess the prevalence of spinal dysraphism in cloacal exstrophy. [MATERIALS AND METHODS] Ten infants under 1 year old with cloacal exstrophy underwent spinal ultrasoun...
null
0.653
110
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,001
11,285,968
Laparoscopy reduces unnecessary appendicectomies and improves diagnosis in fertile women. A randomized study.
Surgical endoscopy
Surg Endosc
15
2
10.1007/s004640000255
eng
2,001
2
null
null
null
null
[BACKGROUND] The aim of this study was to study the value of diagnostic laparoscopy prospectively in fertile women scheduled for acute appendectomy. [METHODS] For this study, 110 women, with acute abdominal pain ages 15 to 47 years, in whom the surgeon had decided to perform an appendectomy, were randomized to either o...
null
1.165
178
Surgery
Medicine
2,001
11,285,067
Frequency of portal and systemic bacteremia in acute appendicitis.
Pediatrics international : official journal of the Japan Pediatric Society
Pediatr Int
43
2
10.1046/j.1442-200x.2001.01360.x
eng
2,001
4
null
null
null
null
[BACKGROUND] Acute appendicitis is the most common condition requiring an emergency abdominal operation in childhood. In the present study, we analyzed the frequency of portal and systemic bacteremia in 42 patients with acute appendicitis and determined the microbial agents responsible for an acute appendicitis and for...
null
0.262
76
Pediatrics, Perinatology and Child Health
Medicine
2,001
11,285,060
Retinopathy of prematurity: mutations in the Norrie disease gene and the risk of progression to advanced stages.
Pediatrics international : official journal of the Japan Pediatric Society
Pediatr Int
43
2
10.1046/j.1442-200x.2001.01361.x
eng
2,001
4
null
null
null
null
[BACKGROUND] Retinopathy of prematurity (ROP) is a retinal vascular disease that occurs in infants with short gestational age and low birth weight and may lead to retinal detachment and blindness. Missense mutations in the Norrie disease (ND) gene have been associated with the risk of progression to advanced stages in ...
null
0.262
76
Pediatrics, Perinatology and Child Health
Medicine
2,001
11,284,803
Effect of cetirizine, levocetirizine, and dextrocetirizine on histamine-induced nasal response in healthy adult volunteers.
Allergy
Allergy
56
4
10.1034/j.1398-9995.2001.00775.x
eng
2,001
4
null
null
null
null
[BACKGROUND] Cetirizine, an effective H1-receptor antagonist, is a racemate mixture of two enantiomers: levocetirizine (R enantiomer) and dextrocetirizine (S enantiomer). [METHODS] To investigate the pharmacologic activity of the two enantiomers of cetirizine, we conducted a randomized, double-blind, four-way, crossove...
null
0.887
213
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,001
11,284,480
High performance liquid chromatography analysis of tear protein patterns in diabetic and non-diabetic dry-eye patients.
European journal of ophthalmology
Eur J Ophthalmol
11
1
10.1177/112067210101100105
eng
2,001
null
null
null
null
null
[PURPOSE] To analyze and compare the high performance liquid chromatography (HPLC) runs of tear proteins from diabetic (DIDRY) and non-diabetic (DRY) dry-eye patients, and healthy subjects (CTRL). The patterns were analyzed using multivariate statistical methods. [METHODS] Tears (total 56 eyes: CTRL: n=16, DIDRY: n=21,...
null
0.532
69
Medicine; Ophthalmology
Medicine
2,001
11,284,318
Epithelioid sarcoma. Report of a case with fine needle aspiration diagnosis.
Acta cytologica
Acta Cytol
45
2
10.1159/000327289
eng
2,001
null
null
null
null
null
[BACKGROUND] Epithelioid sarcoma is a rare type of soft tissue sarcoma affecting the extremities, particularly the hands and fingers. Though it is well described histopathologically, publications regarding its cytologic findings are limited. [CASE] A 52-year-old woman presented with swelling of the left middle finger. ...
null
0.639
67
Medicine; Pathology and Forensic Medicine; Histology
Medicine
2,001
11,283,878
Absent peritoneal fluid on screening trauma ultrasonography in children: a prospective comparison with computed tomography.
Journal of pediatric surgery
J Pediatr Surg
36
4
10.1053/jpsu.2001.22283
eng
2,001
4
null
null
null
null
[BACKGROUND] Although the accuracy of focused abdominal sonography for trauma (FAST) in adults has been demonstrated, results of this technique in children have been conflicting with few comparisons against computed tomography (CT), the imaging gold standard. [METHODS] A total of 160 hemodynamically stable pediatric tr...
null
0.804
147
Medicine; Pediatrics, Perinatology and Child Health; Surgery
Medicine
2,001
11,283,875
Adrenocortical tumors in children.
Journal of pediatric surgery
J Pediatr Surg
36
4
10.1053/jpsu.2001.22280
eng
2,001
4
null
null
null
null
[BACKGROUND/PURPOSE] Etiopathogenesis and management of pediatric adrenocortical tumors (ACTs) is still obscure because of the limited number of cases. The aim of this study is to present a clear picture of the entire spectrum of pediatric ACTs by reviewing one of the largest noncollected pediatric series treated in a ...
null
0.804
147
Medicine; Pediatrics, Perinatology and Child Health; Surgery
Medicine
2,001
11,283,418
Does the trabecular bone structure depicted by high-resolution MRI of the calcaneus reflect the true bone structure?
Investigative radiology
Invest Radiol
36
4
10.1097/00004424-200104000-00003
eng
2,001
4
null
null
null
null
[RATIONALE AND OBJECTIVES] The purpose of this study was to compare trabecular bone structure parameters assessed with high-resolution magnetic resonance imaging (HR-MRI) with those determined in specimen sections. [METHODS] High-resolution MR images were obtained for 30 calcaneus specimens with a three-dimensional, T1...
null
1.272
132
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,001
11,282,902
Randomized trial of aspirin, sibrafiban, or both for secondary prevention after acute coronary syndromes.
Circulation
Circulation
103
13
10.1161/01.cir.103.13.1727
eng
2,001
4
3
null
null
null
[BACKGROUND] The first Sibrafiban Versus Aspirin to Yield Maximum Protection From Ischemic Heart Events Post-Acute Coronary Syndromes (SYMPHONY) trial showed no benefit of 2 doses of sibrafiban over aspirin for secondary prevention after acute coronary syndromes. In 2nd SYMPHONY, we compared low-dose sibrafiban plus as...
null
5.548
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,001
11,282,808
Prophylactic effect of citalopram in unipolar, recurrent depression: placebo-controlled study of maintenance therapy.
The British journal of psychiatry : the journal of mental science
Br J Psychiatry
178
null
10.1192/bjp.178.4.304
eng
2,001
4
null
null
null
null
[BACKGROUND] Major depression is highly recurrent. Antidepressant maintenance treatment has proven efficacy against recurrent depression. [AIMS] Comparison of prophylactic efficacy of citalopram versus placebo in unipolar, recurrent depression. [METHODS] Patients 18-65 years of age with recurrent unipolar major depress...
null
2.493
264
Medicine; Psychiatry and Mental Health
Medicine
2,001
11,281,555
Mechanisms for experimental buprenorphine hepatotoxicity: major role of mitochondrial dysfunction versus metabolic activation.
Journal of hepatology
J Hepatol
34
2
10.1016/s0168-8278(00)00050-7
eng
2,001
2
null
null
null
null
[BACKGROUND/AIMS] Although sublingual buprenorphine is safely used as a substitution drug in heroin addicts, large overdoses or intravenous misuse may cause hepatitis. Buprenorphine is N-dealkylated to norbuprenorphine by CYP3A. [METHODS] We investigated the mitochondrial effects and metabolic activation of buprenorphi...
null
1.469
319
Hepatology
Medicine
2,001
11,281,432
Eosinophilic fasciitis occurring four weeks after the onset of dialysis in a renal failure patient.
Journal of cutaneous medicine and surgery
J Cutan Med Surg
5
1
10.1177/120347540100500108
eng
2,001
null
null
null
null
null
[BACKGROUND] Eosinophilic fasciitis is a rare, scleroderma-like disease that usually affects the extremities of young to middle-aged males. The disease may cause flexion contractures and limit joint mobility and is associated with peripheral eosinophilia. The fascia, by definition, is infiltrated with mononuclear cells...
null
0.334
58
Dermatology; Surgery
Medicine
2,001
11,280,674
Chronic obstructive pulmonary disease patients with invasive pulmonary aspergillosis: benefits of intensive care?
Intensive care medicine
Intensive Care Med
27
1
10.1007/s001340000768
eng
2,001
1
null
null
null
null
[OBJECTIVES] Invasive pulmonary aspergillosis (IPA) is increasingly recognized as a cause of acute respiratory failure in patients with chronic obstructive pulmonary disease (COPD) treated with corticosteroids. For these patients admission in intensive care unit (ICU) is often required for life-support and mechanical v...
null
0.868
246
Critical Care and Intensive Care Medicine
Medicine
2,001
11,280,081
Genetic insights into schizophrenia.
Canadian journal of psychiatry. Revue canadienne de psychiatrie
Can J Psychiatry
46
2
10.1177/070674370104600203
eng
2,001
3
null
null
null
null
[OBJECTIVE] To outline new insights into the genetic etiology of schizophrenia. [METHODS] We discuss several commonly held beliefs about the genetic issues in schizophrenia. [RESULTS] The complex genetic nature of the illness poses a challenge for investigators seeking causative genetic mutations. Multiple independent ...
null
null
null
null
null
null
11,277,888
Warts of the nail unit: surgical and nonsurgical approaches.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
Dermatol Surg
27
3
null
eng
2,001
3
null
null
null
null
[BACKGROUND] Warts are the most common nail tumor and mostly affect children and young adults. Periungual warts are usually due to HPV-1, 2, and 4. Development of periungual warts is favored by maceration and trauma, especially nail biting. [OBJECTIVE] To discuss the biology, clinical features, and medical and surgical...
null
0.852
146
Dermatology; Medicine; Surgery
Medicine
2,001
11,277,197
Comparative efficacy of tricaine methanesulfonate and clove oil for use as anesthetics in red pacu (Piaractus brachypomus).
American journal of veterinary research
Am J Vet Res
62
3
10.2460/ajvr.2001.62.337
eng
2,001
3
null
null
null
null
[OBJECTIVE] To compare the anesthetic efficacy and physiologic changes associated with exposure to tricaine methanesulfonate and clove oil (100% eugenol). [ANIMALS] 15 adult cultured red pacu (Piaractus brachypomus). [PROCEDURE] Fish were exposed to each of 6 anesthetic concentrations in a within-subjects complete cros...
null
0.677
105
Medicine; Veterinary
Medicine; Veterinary
2,001
11,275,949
Relationship between free and total 1,25-dihydroxyvitamin D in conditions of modified binding.
European journal of endocrinology
Eur J Endocrinol
144
4
10.1530/eje.0.1440391
eng
2,001
4
null
null
null
null
[OBJECTIVE] A novel assay was employed to study the free 1,25-dihydroxyvitamin D (1,25(OH)2D) concentrations in various populations with different levels of 1,25(OH)2D and vitamin D binding protein (DBP). [DESIGN] In 12 healthy women before and after 3 months of oral estrogen/progestagen treatment, 10 pregnant women, a...
null
0.791
179
Medicine; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,275,528
Induced electrocorticographic gamma activity during auditory perception. Brazier Award-winning article, 2001.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Clin Neurophysiol
112
4
10.1016/s1388-2457(00)00545-9
eng
2,001
4
null
null
null
null
[OBJECTIVE] To define the spatial, temporal, and functional characteristics of induced gamma (>30 Hz) activity during functional activation of the left superior temporal gyrus. [METHODS] Electrocorticographic (ECoG) recordings were made in 4 clinical subjects during auditory tone and phoneme discrimination tasks, and e...
null
0.789
230
Neurology; Neurology; Physiology; Sensory Systems
Medicine; Neuroscience
2,001
11,274,767
Combining G-CSF with a blockade of adhesion strongly improves the reconstitutive capacity of mobilized hematopoietic progenitor cells.
Experimental hematology
Exp Hematol
29
3
10.1016/s0301-472x(00)00674-3
eng
2,001
3
null
null
null
null
[OBJECTIVE] Mobilization of hematopoietic progenitor cells is achieved mainly by application of growth factors and, more recently, by blockade of adhesion. In this report, we describe the advantages of a combined treatment with granulocyte colony-stimulating factor (G-CSF) and anti-VLA4 (CD49d)/anti-CD44 as compared to...
null
0.674
131
Hematology; Cancer Research; Cell Biology; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,001
11,274,547
Iliac arterial injuries after endovascular repair of abdominal aortic aneurysms: correlation with iliac curvature and diameter.
Radiology
Radiology
219
1
10.1148/radiology.219.1.r01ap15129
eng
2,001
4
null
null
null
null
[PURPOSE] To determine the relationship between iliac arterial tortuosity and cross-sectional area and the occurrence of iliac arterial injuries following transfemoral delivery of endovascular prostheses for repair of abdominal aortic aneurysms. [MATERIALS AND METHODS] Iliac arterial curvature values and orthogonal cro...
null
2.485
346
Radiology, Nuclear Medicine and Imaging
Medicine
2,001
11,274,542
Early prediction of irreversible brain damage after ischemic stroke at CT.
Radiology
Radiology
219
1
10.1148/radiology.219.1.r01ap0695
eng
2,001
4
null
null
null
null
[PURPOSE] To assess the capability of computed tomography (CT) in the prediction of irreversible ischemic brain damage and its association with the clinical course within 6 hours of stroke onset. [MATERIALS AND METHODS] Serial CT scans obtained within 6 hours of stroke onset, at 22-96 hours (median, 1 day), and at 2-36...
null
2.485
346
Radiology, Nuclear Medicine and Imaging
Medicine
2,001
11,274,499
Factors in the use of coercive retention in civil commitment evaluations in psychiatric emergency services.
Psychiatric services (Washington, D.C.)
Psychiatr Serv
52
4
10.1176/appi.ps.52.4.514
eng
2,001
4
null
null
null
null
[OBJECTIVE] The authors examined whether factors other than civil commitment criteria influence the involuntary retention of patients who are evaluated for civil commitment in psychiatric emergency services in California general hospitals. [METHODS] Logistic regression analysis was used to determine whether admission c...
Empirical Approach; Legal Approach; Mental Health Therapies
0.737
174
Medicine; Psychiatry and Mental Health
Medicine
2,001
11,274,269
Evidence for further genetic heterogeneity in nephronophthisis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Nephrol Dial Transplant
16
4
10.1093/ndt/16.4.755
eng
2,001
4
null
null
null
null
[BACKGROUND] A new type of nephronophthisis (NPH) has been recently identified in a large Venezuelan kindred: adolescent nephronophthisis (NPH3) causes end-stage renal disease (ESRD) at a median age of 19 years. The responsible gene (NPHP3) maps to 3q21-q22. NPH3 shares with juvenile nephronophthisis (NPH1) the same di...
null
0.742
203
Medicine; Nephrology; Transplantation
Medicine
2,001
11,273,970
Contact dermatitis in students practicing sports: incidence of rubber sensitisation.
British journal of sports medicine
Br J Sports Med
35
2
10.1136/bjsm.35.2.100
eng
2,001
4
null
null
null
null
[BACKGROUND] Over the last few years, changes in cutaneous homoeostasis resulting from sports activities have been reported. In particular, alterations in sweating mechanisms, the hydrolipid barrier, and surface bacterial flora, together with exposure to atmospheric conditions and the need to use medicaments, detergent...
null
0.631
241
Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,001
11,273,852
Folate intake of the Dutch population according to newly established liquid chromatography data for foods.
The American journal of clinical nutrition
Am J Clin Nutr
73
4
10.1093/ajcn/73.4.765
eng
2,001
4
null
null
null
null
[BACKGROUND] Determining folate intake is difficult because existing folate data in food-composition tables are scarce and unreliable. [OBJECTIVE] The purposes of this study were first to analyze 125 of the most important foods that contribute to folate intake in the Netherlands and second to estimate the folate intake...
null
2.283
390
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,001
11,272,778
Contrast sensitivity following focal laser photocoagulation in clinically significant macular oedema due to diabetic retinopathy.
Clinical & experimental ophthalmology
Clin Exp Ophthalmol
29
1
10.1046/j.1442-9071.2001.00361.x
eng
2,001
2
null
null
null
null
[PURPOSE] To evaluate the influence of focal aser photocoagulation on contrast sensitivity in diabetic patients with clinically significant macular oedema (CSMO). [METHODS] A prospective non-comparative interventional study was performed on a group of patients with CSMO at Dr Rajendra Prasad Centre for Ophthalmic Scien...
null
null
null
null
null
null
11,271,969
Association of outpatient alcohol and drug treatment with health care utilization and cost: revisiting the offset hypothesis.
Journal of studies on alcohol
J Stud Alcohol
62
1
10.15288/jsa.2001.62.89
eng
2,001
1
null
null
null
null
[OBJECTIVE] This study examines the hypothesis that treatment reduces medical utilization and costs of patients with substance use problems. [METHOD] Adult patients (N = 1.011; 67% men) entering the outpatient chemical dependency recovery program at Sacramento Kaiser Permanente over a 2-year period were recruited into ...
null
null
null
null
null
null
11,271,963
Family, religious, school and peer influences on adolescent alcohol use: a longitudinal study.
Journal of studies on alcohol
J Stud Alcohol
62
1
10.15288/jsa.2001.62.44
eng
2,001
1
null
null
null
null
[OBJECTIVE] In this study, the cross-temporal relationship between family social support and adolescent alcohol use was examined. A primary aim was to investigate the mechanisms through which family social support affects drinking among youth. Another aim was to examine reciprocal relationships among the study variable...
null
null
null
null
null
null
11,271,402
Receptor-mediated regulation of serotonin output in the rat dorsal raphe nucleus: effects of risperidone.
Psychopharmacology
Psychopharmacology (Berl)
153
3
10.1007/s002130000582
eng
2,001
1
null
null
null
null
[OBJECTIVES] The present study was undertaken to characterize the regulation of serotonin (5-HT) efflux and neuronal activity in the dorsal raphe nucleus (DRN) as well as to examine the potential ability of the antipsychotic drug risperidone to interfere with these mechanisms. [METHODS AND RESULTS] By using microdialys...
null
1.42
218
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,001
11,270,803
Pharmacokinetics of oral talinolol following a single dose and during steady state in patients with chronic renal failure and healthy volunteers.
International journal of clinical pharmacology and therapeutics
Int J Clin Pharmacol Ther
39
2
10.5414/cpp39061
eng
2,001
2
null
null
null
null
[OBJECTIVE] The objective of this study was to investigate the effect of renal impairment on the pharmacokinetics of the selective beta1-receptor antagonist talinolol. [METHODS] Pharmacokinetic data were obtained in 12 healthy volunteers, 12 patients with renal impairment and 8 patients with terminal renal insufficienc...
null
null
null
null
null
null
11,270,086
Antigens of Fusarium solani: types and criteria for immunochemical characterization.
Allergologia et immunopathologia
Allergol Immunopathol (Madr)
28
5
null
eng
2,000
null
null
null
null
null
[BACKGROUND] There are no established methods for the preparation and standardization of Fusarium solani antigens. This lack of standardization makes it difficult to use these antigens in allergenic diagnostic tests. [OBJECTIVE] To obtain an appropriate standardized method for the preparation of the different antigen t...
null
0.202
47
Medicine; Immunology and Allergy
Medicine
2,000
11,269,468
Time course of cranial ultrasound abnormalities after arterial switch operation in neonates.
The Annals of thoracic surgery
Ann Thorac Surg
71
3
10.1016/s0003-4975(00)02329-8
eng
2,001
3
null
null
null
null
[BACKGROUND] The object of this study was to investigate the time course and fate of abnormal findings in cranial ultrasound after performing an arterial switch operation in neonates with transposition of the great arteries, and to analyze the relationship to cerebral cell damage. [METHODS] Cranial ultrasound was perfo...
null
1.484
230
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,001
11,268,864
Delivery room resuscitation decisions for extremely low birthweight infants in California.
Journal of perinatology : official journal of the California Perinatal Association
J Perinatol
21
1
10.1038/sj.jp.7200477
eng
2,001
null
null
null
null
null
[OBJECTIVE] To characterize physician-parent counseling and delivery room resuscitation of extremely low birthweight (ELBW) infants. [STUDY DESIGN] Cross-sectional survey of 473 California neonatologists detailing counseling patterns, resuscitation thresholds, and acceptance of parental decision making. [RESULTS] The r...
null
0.397
119
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,001
11,268,454
Paclitaxel and carboplatin for recurrent salivary gland malignancies.
Anticancer research
Anticancer Res
20
5C
null
eng
2,000
null
null
null
null
null
[BACKGROUND] The use of chemotherapy for recurrent salivary gland carcinomas is under investigation. [PATIENTS AND METHODS] Fourteen patients (10 males, 4 females; median age 55 years, range 20-70) with recurrent carcinomas of major (9 patients) and minor (5 patients) salivary gland origin (histology: 1 adenocarcinoma,...
null
null
null
null
null
null
11,268,436
Docetaxel, a promising novel chemotherapeutic agent in advanced breast cancer.
Anticancer research
Anticancer Res
20
5C
null
eng
2,000
null
null
null
null
null
[UNLABELLED] Clinical practice in chemotherapy of breast cancer is undergoing changes. This study investigated the efficacy and toxicity of docetaxel, a novel chemotherapeutic agent in metastatic breast cancer. Focus was on the effect of the cumulative dose of previous anthracycline treatment on response rate, toxicity...
null
null
null
null
null
null
11,268,233
Adverse drug effects, compliance, and initial doses of antihypertensive drugs recommended by the Joint National Committee vs the Physicians' Desk Reference.
Archives of internal medicine
Arch Intern Med
161
6
10.1001/archinte.161.6.880
eng
2,001
3
26
null
null
null
[BACKGROUND] Compliance problems are common causes of the inadequate treatment of hypertension, with 16% to 50% of patients quitting treatment within 1 year. Dose-related adverse drug events (ADEs) frequently cause compliance problems, and many ADEs occur with the initial doses of antihypertensive drugs. Thus, it is an...
null
null
null
null
null
null
11,267,719
The effect of 17beta-estradiol on isolated omental arteries from preeclamptic women.
European journal of obstetrics, gynecology, and reproductive biology
Eur J Obstet Gynecol Reprod Biol
95
1
10.1016/s0301-2115(00)00359-6
eng
2,001
3
null
null
null
null
[OBJECTIVE] To study the effect of 17beta-estradiol on isolated omental arteries from preeclamptic women. [STUDY DESIGN] Rings of omental artery with intact endothelium were mounted in organ chambers for isometric tension recording. We studied the effect of pharmacological concentrations of 17beta-estradiol on potassiu...
null
null
null
null
null
null
11,264,625
Reducing postnatal pain from perineal tears by using lignocaine gel: a double-blind randomized trial.
Birth (Berkeley, Calif.)
Birth
28
1
10.1046/j.1523-536x.2001.00022.x
eng
2,001
3
null
null
null
null
[BACKGROUND] Perineal pain is one of the most common causes of maternal morbidity in the early puerperium. Several randomized trials have shown that topical application of local anesthetics is effective in reducing postepisiotomy pain, but no randomized study has assessed the efficacy of local anesthetics for other per...
null
1.161
96
Obstetrics and Gynecology
Medicine
2,001
11,263,625
Stenting versus thrombolysis in acute myocardial infarction trial (STAT).
Journal of the American College of Cardiology
J Am Coll Cardiol
37
4
10.1016/s0735-1097(00)01213-4
eng
2,001
3
15
null
null
null
[OBJECTIVES] We sought to directly compare primary stenting with accelerated tissue plasminogen activator (t-PA) in patients presenting with acute ST-elevation myocardial infarction (AMI). [BACKGROUND] Thrombolysis remains the standard therapy for AMI. However, at some institutions primary angioplasty is favored. Rando...
null
4.039
512
Cardiology and Cardiovascular Medicine
Medicine
2,001
11,262,614
Vasoactive intestinal peptide (VIP) exacerbates endotoxin-induced uveitis (EIU) in mice.
Current eye research
Curr Eye Res
21
6
10.1076/ceyr.21.6.913.6986
eng
2,000
12
null
null
null
null
[PURPOSE] We have previously shown that inhibition of the proinflammatory cytokine tumor necrosis factor- (TNF)-alpha exacerbates the inflammatory process of EIU. To further examine this paradoxic phenomenon, we investigated here the effect on EIU of VIP, a neuropeptide that inbibits TNF-alpha production. [METHODS] VIP...
null
0.831
94
Ophthalmology; Sensory Systems; Cellular and Molecular Neuroscience
Medicine; Neuroscience
2,000
11,262,456
Hormone replacement therapy for bone protection in multiparous women: when to initiate it.
American journal of obstetrics and gynecology
Am J Obstet Gynecol
184
4
10.1067/mob.2001.111247
eng
2,001
3
null
null
null
null
[OBJECTIVE] Hormone replacement therapy is used in postmenopausal women to improve symptoms of menopause and to protect bone and the cardiovascular system. We have evaluated the effects of parity in terms of number of deliveries on bone density and fracture risk at different ages. [STUDY DESIGN] We evaluated 1875 Hispa...
null
1.601
274
Obstetrics and Gynecology
Medicine
2,001
11,260,447
The first sunrise: an experience of cultural immersion and community health needs assessment by undergraduate medical students in New Zealand.
Medical education
Med Educ
35
3
10.1046/j.1365-2923.2001.00772.x
eng
2,001
3
null
null
null
null
[CONTEXT] Cultural factors in health and illness, and an awareness of community health needs analysis, are important issues for medical education. Both have received relatively little recognition in the medical education literature. This paper describes the development of an educational attachment to remote predominant...
null
0.669
171
Education; Medicine
Medicine; Social Sciences
2,001
11,260,411
Incidental renal artery stenosis in peripheral vascular disease: a case for treatment?
Kidney international
Kidney Int
59
4
10.1046/j.1523-1755.2001.0590041480.x
eng
2,001
4
null
null
null
null
[BACKGROUND] Renal artery stenosis (RAS) is frequently encountered as an incidental finding in peripheral vascular disease. We assessed whether revascularization is indicated to prevent the practical consequences of end-stage renal failure, that is, the need for renal replacement therapy. [METHODS] In a retrospective s...
null
null
null
null
null
null
11,260,347
Recovery of sexual function after nerve-sparing radical prostatectomy or cystectomy.
International journal of urology : official journal of the Japanese Urological Association
Int J Urol
8
4
10.1046/j.1442-2042.2001.00274.x
eng
2,001
4
null
null
null
null
[BACKGROUND] The recovery of sexual function (erectile function and frequency of sexual intercourse) over time after nerve-sparing radical prostatectomy or cystoprostatectomy was evaluated. [METHODS] Forty-nine consecutive patients with clinically localized prostate cancer and muscle-invasive bladder cancer were treate...
null
0.378
83
Urology
Medicine
2,001
11,258,851
Role of stress responses in human cell survival following exposure to ultraviolet C radiation.
International journal of radiation biology
Int J Radiat Biol
77
3
10.1080/09553000010012545
eng
2,001
3
null
null
null
null
[PURPOSE] To investigate in human skin and other cells the role of tyrosine kinase and protein kinase-C (PKC) in eliciting cell-signalling responses to UV radiation (UVR) that affect the survival of irradiated cells. [MATERIALS AND METHODS] The survival of HeLa S3 cells, NCTC 2544 human keratinocytes and A431 human epi...
null
1.145
104
Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,001
11,258,436
Induction of hyporesponsiveness to fully allogeneic cardiac grafts by intratracheal delivery of alloantigen.
Transplantation
Transplantation
71
4
10.1097/00007890-200102270-00012
eng
2,001
2
27
null
null
null
[BACKGROUND] Soluble protein delivered through the mucosal surface can induce immunological unresponsiveness. The purpose of this study was to determine if prior exposure to alloantigen via the trachea could modulate the immune response to subsequent cardiac allografts. [METHODS] Hearts from C57BL/10(H2b) mice were tra...
null
1.782
224
Transplantation
Medicine
2,001
11,257,741
Massive fetomaternal transplacental hemorrhage as a perinatology problem, role of ABO fetomaternal compatibility--case studies.
Medical science monitor : international medical journal of experimental and clinical research
Med Sci Monit
7
2
null
eng
2,001
null
null
null
null
null
[BACKGROUND] Massive fetomaternal transplacental hemorrhage is not simply a problem of possible alloimunization in Rh incompatibility but also endangers the fetus (newborn) by massive anemization. Bleeding from placental vessels can occur after small trauma to the gravid uterus with mild or no clinical signs (bleeding ...
null
0.113
107
Medicine
Medicine
2,001
11,257,737
Are antibiotics necessary in nonperforated appendicitis in children? A double blind randomized controlled trial.
Medical science monitor : international medical journal of experimental and clinical research
Med Sci Monit
7
2
null
eng
2,001
null
null
null
null
null
[BACKGROUND] The use of antibiotics in uncomplicated appendicitis in children, remains the area of controversy. The aim of the study was to assess the necessity of antibiotic administration in nonperforated appendicitis in children. [MATERIAL AND METHODS] The design of the study was a double blind randomized controlled...
null
0.113
107
Medicine
Medicine
2,001
11,257,710
Scatter factor-hepatocyte growth factor elevation in the serum of patients with prostate cancer.
The Journal of urology
J Urol
165
4
null
eng
2,001
4
null
null
null
null
[PURPOSE] Scatter factor (SF), also known as hepatocyte growth factor (HGF), has been shown to induce proliferation, scattering and invasiveness in human prostate cancer cell lines. In this study we determined the serum level of SF-HGF in men with metastatic prostate cancer compared to those with localized prostate can...
null
1.655
291
Urology
Medicine
2,001
11,257,664
The use of an artificial urinary sphincter in women with type III incontinence and a negative Marshall test.
The Journal of urology
J Urol
165
4
null
eng
2,001
4
null
null
null
null
[PURPOSE] We evaluate the efficacy of the AMS 800 artificial urinary sphincter in women with type III incontinence. [MATERIALS AND METHODS] We enrolled 207 women with genuine stress incontinence due to intrinsic sphincter deficiency. Primary inclusion criterion was a negative Marshall test. A modified surgical procedur...
null
1.655
291
Urology
Medicine
2,001