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12,072,614
The effect of midline petrous apex lesions on tests of afferent and efferent auditory function.
Ear and hearing
Ear Hear
23
3
10.1097/00003446-200206000-00006
eng
2,002
6
null
null
null
null
[OBJECTIVES] Historically, audiological procedures have focused on the assessment of the afferent (ascending) cochlear-VIIIth nerve system and have, for the most part, ignored the efferent (descending) auditory system. We report afferent and efferent auditory test results for two cases with a cholesterol cyst of the ri...
null
null
null
null
null
null
12,072,123
Psychological impact of torture: a 3-month follow-up of mass-evacuated Kosovan adults in Sweden. Lessons learnt for prevention.
Acta psychiatrica Scandinavica. Supplementum
Acta Psychiatr Scand Suppl
null
412
10.1034/j.1600-0447.106.s412.7.x
eng
2,002
null
null
null
null
null
[OBJECTIVE] To study the impact of torture on symptomatology among mass displaced adults. [METHOD] A sample (total 131; 70 females, 61 males) of mass displaced adults from Kosovo, in Sweden, completed 3 months after a baseline study on trauma experiences and perceived symptoms, self-rated instruments measuring psychiat...
null
null
null
null
null
null
12,072,075
Comparative frequency of patch test reactions to topical antibiotics.
The British journal of dermatology
Br J Dermatol
146
6
10.1046/j.1365-2133.2002.04662.x
eng
2,002
6
null
null
null
null
[BACKGROUND] Neomycin, clioquinol and fusidic acid are all topical antibiotics widely used in dermatological practice in the U.K., either as a single agent or in combination with topical corticosteroids. However, an adverse effect of topical antibiotics is contact sensitization. [OBJECTIVES] To examine the frequency of...
null
1.248
214
Dermatology; Medicine
Medicine
2,002
12,071,512
Regulation of ER stress proteins by valproate: therapeutic implications.
Bipolar disorders
Bipolar Disord
4
2
10.1034/j.1399-5618.2002.t01-1-40201.x
eng
2,002
4
null
null
null
null
[OBJECTIVES] This paper reviews results of our studies examining the regulation of endoplasmic reticulum (ER) stress proteins by valproate (VPA). and discusses the possible implications in bipolar disorder. [METHODS] Our previous studies in the field are reviewed along with relevant literature. [RESULTS] Using differen...
null
1.596
145
Biological Psychiatry; Psychiatry and Mental Health
Medicine; Neuroscience
2,002
12,071,238
Subcutaneous epinephrine administration decreases lower oesophageal sphincter pressure and gastro-oesophageal pressure gradient in children under general anaesthesia.
European journal of anaesthesiology
Eur J Anaesthesiol
19
3
10.1017/s0265021502000339
eng
2,002
3
null
null
null
null
[BACKGROUND AND OBJECTIVE] Children are vulnerable to regurgitation with a relatively high incidence of aspiration during general anaesthesia which is attributed to the high intragastric pressure, a short oesophagus, an immature laryngeal reflex and incomplete lower oesophageal sphincter muscle function. Subcutaneous a...
null
0.547
94
Anesthesiology and Pain Medicine
Medicine
2,002
12,070,585
Articular chondrocalcinosis in Saudi Arabia.
Saudi medical journal
Saudi Med J
23
5
null
eng
2,002
5
null
null
null
null
[OBJECTIVE] To investigate the prevalence of articular chondrocalcinosis in subjects aged 50 years and above in a radiographic survey through 14 primary care clinics in North Riyadh, Kingdom of Saudi Arabia. [METHODS] Over a period of 7 months extending from September 1998 to March 1999, 153 patients attending 14 prima...
null
null
null
null
null
null
12,070,573
A pilot study of cardiac troponin I in patients with acute myocardial infarction and unstable angina.
Saudi medical journal
Saudi Med J
23
5
null
eng
2,002
5
null
null
null
null
[OBJECTIVE] To assess the value of cardiac troponin I in the initial management of acute myocardial infarction and unstable angina, as well as the concordance between creatine phosphokinase-cardiac isoenzyme and cardiac troponin I. [METHODS] We reviewed retrospectively the charts of 32 patients with acute myocardial in...
null
null
null
null
null
null
12,070,548
Malaria parasitemia during delivery.
Saudi medical journal
Saudi Med J
23
6
null
eng
2,002
6
null
null
null
null
[OBJECTIVE] The aim of this study is to investigate the impact of plasmodium falciparum infection in parturient women in Central Sudan where malaria transmission is mesoendemic. The purpose of this paper is to find out the prevalence of malaria parasitemia and the risk of anemia among parturient women and to suggest ap...
null
null
null
null
null
null
12,070,541
Are women at an increased risk of gestational thyrotoxicosis?
Saudi medical journal
Saudi Med J
23
6
null
eng
2,002
6
null
null
null
null
[OBJECTIVE] To evaluate the relative importance of thyroid hormones and human chorionic gonadotropin in relation to the risk of gestational thyrotoxicosis in Saudi women living in Jeddah, Kingdom of Saudi Arabia. [METHODS] A prospective study was conducted on Saudi healthy pregnant women (N=406) at 12-15 weeks of gesta...
null
null
null
null
null
null
12,070,423
Cyclic nitric oxide release by human granulocytes, and invertebrate ganglia and immunocytes: nano-technological enhancement of amperometric nitric oxide determination.
Medical science monitor : international medical journal of experimental and clinical research
Med Sci Monit
8
6
null
eng
2,002
6
null
null
null
null
[BACKGROUND] Various tissues from vertebrates and invertebrates respond to external signal molecules by rapid release of nitric oxide (NO) mediated by constitutive nitric oxide synthase. [MATERIAL/METHODS] Invertebrate immunocytes were collected from maintained stock and human granulocytes were isolated from leukocyte-...
null
0.186
107
Medicine
Medicine
2,002
12,069,198
Autoimmune hepatitis complicated with antiphospholipid syndrome in pregnancy.
American journal of reproductive immunology (New York, N.Y. : 1989)
Am J Reprod Immunol
47
3
10.1034/j.1600-0897.2002.1c082.x
eng
2,002
3
null
null
null
null
[PROBLEM] There are few reports on the association between autoimmune hepatitis (AIH) and antiphospholipid syndrome; only five reports were found on a MEDLINE search between 1966 and 2001. Therefore, the etiology and the optimal treatment of them are not clear. [METHOD OF STUDY] We encountered a case of AIH complicated...
null
0.669
119
Obstetrics and Gynecology; Reproductive Medicine; Immunology and Allergy; Immunology
Immunology and Microbiology; Medicine
2,002
12,068,988
Evaluation of an amplified Mycobacterium tuberculosis direct test in clinical specimens.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease
Int J Tuberc Lung Dis
6
6
10.5588/09640569513066
eng
2,002
6
null
null
null
null
[SETTING] An increase in tuberculosis cases has been observed since the last decade, and rapid and specific tests are needed to directly detect Mycobacterium tuberculosis in respiratory specimens. The Amplified Mycobacterium Tuberculosis Direct Test (AMTDT) is a direct specimen assay for the identification of M. tuberc...
null
1.444
124
Infectious Diseases; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,002
12,068,255
Detection and localization of protein-acetaldehyde adducts in rat brain after chronic ethanol treatment.
Alcoholism, clinical and experimental research
Alcohol Clin Exp Res
26
6
null
eng
2,002
6
null
null
null
null
[BACKGROUND] Ethanol is metabolized to acetaldehyde in the cell, which is potentially deleterious because it can react with cellular proteins and form protein-acetaldehyde adducts, which can interfere with normal cellular function. Because the primary site of ethanol action is the brain, the present study was carried o...
null
null
null
null
null
null
12,068,193
Fecal incontinence severity index after fistulotomy: a predictor of quality of life.
Diseases of the colon and rectum
Dis Colon Rectum
45
3
10.1007/s10350-004-6181-5
eng
2,002
3
null
null
null
null
[PURPOSE] The purpose of this study was to use the Fecal Incontinence Severity Index to assess fecal incontinence after fistulotomy and to correlate the Fecal Incontinence Severity Index score with quality-of-life measures. [METHODS] A retrospective chart review was performed on consecutive patients undergoing fistulot...
null
1.235
185
Gastroenterology; Medicine
Medicine
2,002
12,067,375
Oligonucleotide probe for detecting Enterobacteriaceae by in situ hybridization.
Journal of applied microbiology
J Appl Microbiol
93
1
10.1046/j.1365-2672.2002.01668.x
eng
2,002
null
null
null
null
null
[AIMS] To develop oligonucleotide probes for visualizing bacteria belonging to Enterobacteriaceae. [METHODS AND RESULTS] 24-mer oligonucleotide probe (probe D) was designed by comparison of 16S rDNA sequences of 35 species of Enterobacteriaceae, eight species of Vibrionaceae and six species of Pasteurellaceae. The sequ...
null
0.905
195
Applied Microbiology and Biotechnology; Biotechnology; Medicine
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,002
12,066,998
Ultrasonographic assessment of topographic anatomy in volunteers suggests a modification of the infraclavicular vertical brachial plexus block.
British journal of anaesthesia
Br J Anaesth
88
5
10.1093/bja/88.5.632
eng
2,002
5
null
null
null
null
[BACKGROUND] The infraclavicular vertical brachial plexus block, first described by Kilka and coworkers, offers a more proximal spread of anaesthesia for the upper extremity than the classic axillary approach. In this technique, the puncture site is defined as lying at the exact centre of an infraclavicular line (k) be...
null
1.142
222
Anesthesiology and Pain Medicine
Medicine
2,002
12,066,942
Possible association between amniotic fluid micro-organism infection and microflora in the mouth.
BJOG : an international journal of obstetrics and gynaecology
BJOG
109
5
10.1111/j.1471-0528.2002.01349.x
eng
2,002
5
null
null
null
null
[OBJECTIVE] To determine whether oral bacteria are found in the amniotic cavity. [DESIGN] Laboratory based analysis of clinical samples. [SETTING] Royal London Hospital, Whitechapel. [POPULATION] Forty-eight women attending for elective caesarean section. [METHODS] Dental plaque, a high vaginal swab, amniotic fluid and...
null
1.091
195
Obstetrics and Gynecology
Medicine
2,002
12,066,938
The decision-to-delivery interval for emergency caesarean section: is 30 minutes a realistic target?
BJOG : an international journal of obstetrics and gynaecology
BJOG
109
5
10.1111/j.1471-0528.2002.00491.x
eng
2,002
5
null
null
null
null
[OBJECTIVE] To evaluate whether a 30-minute decision-to-delivery interval is a realistic target for emergency caesarean section. [DESIGN] An audit of all emergency caesarean sections over five separate periods. [SETTING] A district general hospital. [PARTICIPANTS] Five groups of women (343 women) with an indication for...
null
1.091
195
Obstetrics and Gynecology
Medicine
2,002
12,066,672
The influence of surface configuration on the retention of posts designed for use with a cast-on technique.
Quintessence international (Berlin, Germany : 1985)
Quintessence Int
32
2
null
eng
2,001
2
null
null
null
null
[OBJECTIVES] The combination of an individually cast core and a prefabricated metal post is one of the many techniques to restore endodontically treated teeth. The surface characteristics of commercially available posts vary considerably and likely influence retention. In this study, the surface configuration of 11 cas...
null
null
null
null
null
null
12,066,670
Tray delivery of potassium nitrate-fluoride to reduce bleaching sensitivity.
Quintessence international (Berlin, Germany : 1985)
Quintessence Int
32
2
null
eng
2,001
2
null
null
null
null
[OBJECTIVE] Tooth sensitivity is a common side effect associated with tooth whitening. The purpose of this study was to determine if bleaching tray delivery of potassium nitrate-fluoride reduces bleaching sensitivity enough to allow continuation of whitening treatment. [METHOD AND MATERIALS] Thirty patients were enroll...
null
null
null
null
null
null
12,066,486
Shock absorbability and hardness of commercially available denture teeth.
The International journal of prosthodontics
Int J Prosthodont
15
3
null
eng
2,002
null
null
null
null
null
[PURPOSE] Composite resin teeth are more widely used than porcelain or acrylic resin teeth in the fabrication of removable dentures because of their high fracture toughness and high abrasion resistance. The purpose of this study was to evaluate the shock absorbability of commercially available artificial posterior teet...
null
0.632
110
Medicine; Oral Surgery
Dentistry; Medicine
2,002
12,065,977
Biomechanical evaluation of an injectable calcium phosphate cement for vertebroplasty.
Spine
Spine (Phila Pa 1976)
27
12
10.1097/00007632-200206150-00010
eng
2,002
6
15
null
null
null
[STUDY DESIGN] Destructive biomechanical tests using fresh cadaveric thoracolumbar vertebral bodies. [OBJECTIVES] To evaluate the compression strength of human vertebral bodies injected with a new calcium phosphate (CaP) cement with improved infiltration properties for augmentation of the vertebral bodies before compre...
null
1.336
300
Neurology; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,002
12,065,955
Natural history of 70 fetuses with a prenatally diagnosed orofacial cleft.
Fetal diagnosis and therapy
Fetal Diagn Ther
17
4
10.1159/000063402
eng
2,002
null
null
null
null
null
[OBJECTIVE] This study is an analysis of neonatal outcome in 70 fetuses diagnosed over a 10-year period as having cleft lip with or without cleft palate (CL-P) by ultrasonographic examination. [METHODS] We describe the natural history of these 70 fetuses with orofacial clefts and select those who may be candidates for ...
null
0.496
75
Medicine; Embryology; Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health; Radiology, Nuclear Medicine and Imaging
Medicine
2,002
12,065,909
Identification and characterisation of the IgE-binding proteins 2S albumin and conglutin gamma in almond (Prunus dulcis) seeds.
International archives of allergy and immunology
Int Arch Allergy Immunol
128
2
10.1159/000059399
eng
2,002
6
null
null
null
null
[BACKGROUND] Almond proteins can cause severe anaphylactic reactions in susceptible individuals. The aim of this study was the identification of IgE-binding proteins in almonds and the characterisation of these proteins by N-terminal sequencing. [METHODS] Five sera were selected from individuals with a positive reactio...
null
0.784
115
Medicine; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,002
12,065,555
Hepatocellular carcinoma in children and adolescents: results from the Pediatric Oncology Group and the Children's Cancer Group intergroup study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
J Clin Oncol
20
12
10.1200/JCO.2002.06.155
eng
2,002
6
15
null
null
null
[PURPOSE] To determine surgical resectability, event-free survival (EFS), and toxicity in children with hepatocellular carcinoma (HCC) randomized to treatment with either cisplatin (CDDP), vincristine, and fluorouracil (regimen A) or CDDP and continuous-infusion doxorubicin (regimen B). [PATIENTS AND METHODS] Forty-six...
null
4.274
646
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
12,065,356
Vocal cord paralysis after surgery for thoracic aortic aneurysm.
Chest
Chest
121
6
10.1378/chest.121.6.1911
eng
2,002
6
null
null
null
null
[OBJECTIVE] To determine the incidence, etiology, prognosis, and treatment of vocal cord paralysis (VCP) after surgery for thoracic aortic aneurysm (TAA). [STUDY DESIGN] Retrospective study performed between 1989 and 1995. [SETTING] Academic, tertiary care, referral medical center. [PATIENTS] Seventy-one TAA patients u...
null
1.171
337
Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine
Medicine
2,002
12,064,837
No association of vitamin D receptor gene start codon fok 1 polymorphisms in Chinese patients with systemic lupus erythematosus.
The Journal of rheumatology
J Rheumatol
29
6
null
eng
2,002
6
null
null
null
null
[OBJECTIVE] To examine whether the start codon Fok I of the vitamin D receptor (VDR) gene polymorphism is a marker of susceptibility to or severity of systemic lupus erythematosus (SLE) in Chinese patients in Taiwan. [METHODS] A control group of 90 healthy people and 52 patients with SLE were examined. Using polymerase...
null
1.022
201
Rheumatology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,002
12,064,830
Treatment of chronic knee synovitis with arthroscopic synovectomy: longterm results.
The Journal of rheumatology
J Rheumatol
29
6
null
eng
2,002
6
null
null
null
null
[OBJECTIVE] We examined the longterm results of arthroscopic synovectomy in chronic knee synovitis of rheumatoid arthritis (RA). [METHODS] Forty-one knees of 38 patients (30 women, 8 men), mean age of 42.7 +/- 15.3 years, were evaluated clinically and radiographically at a mean 8.9 years (range 5.0-12.3) after arthrosc...
null
1.022
201
Rheumatology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,002
12,063,950
Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma.
Hepato-gastroenterology
Hepatogastroenterology
49
45
null
eng
2,002
null
null
null
null
null
[BACKGROUND/AIMS] Genetic alterations are considered to play an important role in both the carcinogenesis and biological behavior of human malignancies. However, the clinical implications of intrahepatic cholangiocarcinoma are poorly understood. We investigated the microsatellite instability, K-ras gene mutations and p...
null
0.527
84
Gastroenterology; Medicine; Hepatology
Medicine
2,002
12,063,215
Is percutaneous vertebroplasty without pretreatment venography safe? Evaluation of 205 consecutives procedures.
AJNR. American journal of neuroradiology
AJNR Am J Neuroradiol
23
6
null
eng
2,002
null
null
null
null
null
[BACKGROUND AND PURPOSE] Vertebral venography has been advocated before bone cement injection when performing percutaneous vertebroplasty (PV) for benign or malignant lesions of the spine. Although venography can document sites of potential leakage during subsequent cement application, stagnant contrast agent renders t...
null
null
null
null
null
null
12,063,203
A model of how students link problem-based learning with clinical experience through "elaboration".
Academic medicine : journal of the Association of American Medical Colleges
Acad Med
77
6
10.1097/00001888-200206000-00015
eng
2,002
6
null
null
null
null
[PURPOSE] In 1994, the medical school at the University of Manchester introduced a new integrated course that uses problem-based learning (PBL) throughout the clinical clerkships as the major approach for delivery of the core curriculum. This study explored how students linked PBL and clinical experiences. [METHOD] All...
null
0.78
199
Education; Medicine
Medicine; Social Sciences
2,002
12,063,148
Bipolar disorder in the general population in The Netherlands (prevalence, consequences and care utilisation): results from The Netherlands Mental Health Survey and Incidence Study (NEMESIS).
Journal of affective disorders
J Affect Disord
68
2-3
10.1016/s0165-0327(00)00310-4
eng
2,002
4
null
null
null
null
[BACKGROUND] Little is known about the prevalence of bipolar disorder in the general population, what proportion is receiving care and what factors motivate people to seek help. [METHOD] Data were derived from The Netherlands Mental Health Survey and Incidence Study (NEMESIS), a psychiatric epidemiological study in the...
null
1.427
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,002
12,063,048
Fornix and conjunctiva reconstruction by amniotic membrane in a patient with conjunctival mucosa-associated lymphoid tissue lymphoma.
Japanese journal of ophthalmology
Jpn J Ophthalmol
46
3
10.1016/s0021-5155(02)00476-8
eng
2,002
null
null
null
null
null
[BACKGROUND] Conjunctival mucosa-associated lymphoid tissue (MALT) lymphoma is a rare, low-grade, non-Hodgkin's B-cell lymphoma. Herein, we report our successful management of the large conjunctival defect caused by resection of conjunctival MALT lymphoma by covering it with transplanted amniotic membrane. [CASE] A 28-...
null
0.426
70
Medicine; Ophthalmology
Medicine
2,002
12,063,040
Laser subepithelial keratomileusis for low to moderate myopia: 6-month follow-up.
Japanese journal of ophthalmology
Jpn J Ophthalmol
46
3
10.1016/s0021-5155(02)00473-2
eng
2,002
null
null
null
null
null
[PURPOSE] To examine the effectiveness, safety, and stability of laser subepithelial keratomileusis (LASEK), a modified photorefractive keratectomy for low to moderate myopia. [METHODS] This study evaluated the results of LASEK in 48 myopic patients (84 eyes) with a consecutive 6-month follow-up period. Preoperative my...
null
0.426
70
Medicine; Ophthalmology
Medicine
2,002
12,062,350
Enalapril effects on atrial remodeling and atrial fibrillation in experimental congestive heart failure.
Cardiovascular research
Cardiovasc Res
54
2
10.1016/s0008-6363(02)00243-2
eng
2,002
5
null
null
null
null
[OBJECTIVE] Atrial remodeling contributes to the maintenance of atrial fibrillation (AF) in several cardiac disorders. There is evidence that angiotensin-converting enzyme (ACE) inhibitors reduce the prevalence of AF in patients with congestive heart failure (CHF). There have been no studies performed to assess the eff...
null
null
null
null
null
null
12,062,349
Daily oral verapamil before but not after rapid atrial excitation prevents electrical remodeling.
Cardiovascular research
Cardiovasc Res
54
2
10.1016/s0008-6363(02)00269-9
eng
2,002
5
null
null
null
null
[BACKGROUND] Intravenous verapamil has been reported to prevent electrical remodeling induced by rapid atrial excitation of several minutes to several hours. However, the clinical efficacy of verapamil when taken orally and daily remains controversial. [PURPOSE] We attempted to demonstrate our hypothesis that if verapa...
null
null
null
null
null
null
12,062,335
Thoracic veins and the mechanisms of non-paroxysmal atrial fibrillation.
Cardiovascular research
Cardiovasc Res
54
2
10.1016/s0008-6363(01)00554-5
eng
2,002
5
null
null
null
null
[OBJECTIVE] The purpose of this article is to review the importance of thoracic veins in the maintenance of sustained (non-paroxysmal) atrial fibrillation (AF). [METHODS] Thoracic veins, including the pulmonary veins (PVs), vein of Marshall (VOM) and the superior vena cava (SVC), have muscle sleeves that connect to the...
null
null
null
null
null
null
12,061,743
Prediction of treatment response of head and neck cancers with P-31 MR spectroscopy from pretreatment relative phosphomonoester levels.
Academic radiology
Acad Radiol
9
6
10.1016/s1076-6332(03)80314-8
eng
2,002
6
null
null
null
null
[RATIONALE AND OBJECTIVES] Combinations of chemotherapy and fractionated radiation therapy are the currently preferred nonsurgical treatment methods for squamous cell carcinoma of the head and neck, but to the authors' knowledge there is no reliable marker for predicting therapeutic response. Early identification of no...
null
0.682
113
Radiology, Nuclear Medicine and Imaging
Medicine
2,002
12,060,505
Fluconazole versus ketoconazole in the treatment of tinea versicolor.
The Journal of dermatological treatment
J Dermatolog Treat
13
2
10.1080/095466302317584421
eng
2,002
6
null
null
null
null
[BACKGROUND] A number of effective topical therapies are available for the treatment of tinea versicolor (TV). However, topical antifungals are difficult to apply to a large body surface area and for this reason TV is perhaps more easily treated with systemic agents. [METHODS] A total of 128 patients with TV, aged 15-5...
null
0.3
69
Dermatology
Medicine
2,002
12,060,020
Different neurophysiologic patterns of myoclonus characterize Lennox-Gastaut syndrome and myoclonic astatic epilepsy.
Epilepsia
Epilepsia
43
6
10.1046/j.1528-1157.2002.30301.x
eng
2,002
6
null
null
null
null
[PURPOSE] To study the neurophysiologic characteristics of epileptic myoclonus in patients with Lennox-Gastaut syndrome (LGS) and myoclonic astatic epilepsy (MAE). [METHODS] Three patients with symptomatic LGS (mean age, 15 years +/- 4) and three with cryptogenic MAE (mean age, 9 years +/- 3) were studied. Temporal rel...
null
1.365
228
Neurology; Neurology
Medicine; Neuroscience
2,002
12,059,988
Factorial study of the effects of atorvastatin and fish oil on dyslipidaemia in visceral obesity.
European journal of clinical investigation
Eur J Clin Invest
32
6
10.1046/j.1365-2362.2002.01001.x
eng
2,002
6
null
null
null
null
[BACKGROUND] Dyslipidaemia may account for increased risk of cardiovascular disease in central obesity. Pharmacotherapy is often indicated in these patients, but the optimal approach remains unclear. We investigated the effects of atorvastatin and fish oil on plasma lipid and lipoprotein levels, including remnant-like ...
null
0.907
126
Clinical Biochemistry; Medicine; Biochemistry
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
12,059,913
Bacterial and fungal microleakage of AH26 and AH Plus root canal sealers.
International endodontic journal
Int Endod J
35
5
10.1046/j.1365-2591.2002.00490.x
eng
2,002
5
null
null
null
null
[AIM] To evaluate the penetration of Candida albicans alone and a combination of bacteria through root canals filled with gutta-percha and one or other root canal sealers, AH26 and AH Plus. [METHODOLOGY] Eighty teeth were randomly divided into two groups of 40 teeth each and obturated with gutta-percha using either AH2...
null
0.791
157
Dentistry
Dentistry
2,002
12,057,717
N-acetyl-cysteine treatment improves insulin sensitivity in women with polycystic ovary syndrome.
Fertility and sterility
Fertil Steril
77
6
10.1016/s0015-0282(02)03133-3
eng
2,002
6
null
null
null
null
[OBJECTIVE] To evaluate the effect of N-acetyl-cysteine (NAC) on insulin secretion and peripheral insulin resistance in subjects with polycystic ovary syndrome (PCOS). [DESIGN] Prospective data analysis. [SETTING] Volunteer women in an academic research environment. [PATIENT(S)] Six lean and 31 obese subjects, aged 19-...
null
1.385
252
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,002
12,056,962
Hypopigmentation associated with an adenovirus-mediated gp100/MART-1-transduced dendritic cell vaccine for metastatic melanoma.
Archives of dermatology
Arch Dermatol
138
6
10.1001/archderm.138.6.799
eng
2,002
6
null
null
null
null
[BACKGROUND] Reports of vitiligo associated with metastases and rare cases of spontaneous regression of disease have fueled enthusiasm for immunologic approaches to the treatment of advanced melanoma. More recent strategies have focused on using antigen-presenting dendritic cells as vaccines. [OBSERVATIONS] We observed...
null
null
null
null
null
null
12,056,959
Product-related emphasis of skin disease information online.
Archives of dermatology
Arch Dermatol
138
6
10.1001/archderm.138.6.775
eng
2,002
6
null
null
null
null
[BACKGROUND] In 2000, 41 million people searched for medical information online. The quality of that information is unregulated, variable, and not well studied. [OBJECTIVE] To quantify and compare the numbers and types of Internet sites matched for 10 diverse skin conditions through different search systems. [DESIGN] S...
null
null
null
null
null
null
12,056,730
Feasibility of the ross procedure: its relationship with the bicuspid aortic valve.
The Journal of heart valve disease
J Heart Valve Dis
11
3
null
eng
2,002
5
null
null
null
null
[BACKGROUND AND AIM OF THE STUDY] The feasibility of the Ross procedure, and which patients benefit most from its performance, have not yet been fully established. The study aim was to analyze the relationship between the etiology of aortic valve disease, the feasibility of performing the Ross procedure, and late pulmo...
null
null
null
null
null
null
12,056,406
Should measurement of maximum urinary flow rate and residual urine volume be a part of a "minimal care" assessment programme in female incontinence?
Scandinavian journal of urology and nephrology
Scand J Urol Nephrol
36
2
10.1080/003655902753679418
eng
2,002
null
null
null
null
null
[OBJECTIVE] The aim of this study was to evaluate the value of routine measurements of urinary flow rate and residual urine volume as a part of a "minimal care" assessment programme for women with urinary incontinence in detecting clinical significant bladder emptying problems. [MATERIAL AND METHODS] Four hundred and e...
null
null
null
null
null
null
12,053,130
Posterior cortical atrophy: clinical characteristics and differences compared to Alzheimer's disease.
Dementia and geriatric cognitive disorders
Dement Geriatr Cogn Disord
14
1
10.1159/000058331
eng
2,002
null
null
null
null
null
[BACKGROUND] Predominant and progressive complex visual disorders are often due to posterior cortical atrophy (PCA), a rare early-onset dementing syndrome presenting with visual complaints. In clinicopathological studies, PCA is most commonly considered a form of Alzheimer's disease (AD); no prior study has evaluated c...
null
1.194
127
Geriatrics and Gerontology; Psychiatry and Mental Health; Cognitive Neuroscience
Medicine; Neuroscience
2,002
12,052,426
Computerisation, coding, data retrieval and related attitudes among Swedish general practitioners-a survey of necessary conditions for a database of diseases and health problems.
International journal of medical informatics
Int J Med Inform
65
2
10.1016/s1386-5056(02)00012-6
eng
2,002
6
null
null
null
null
[OBJECTIVE] To investigate necessary conditions for the establishment of a database of diseases and health problems for research and health care planning, based on electronic patient records in everyday clinical use among general practitioners (GPs). [DESIGN] Postal questionnaire study. [SETTING] Primary health care in...
null
0.48
141
Health Informatics
Medicine
2,002
12,052,098
Estimating the effect of changes in body mass index on health state preferences.
PharmacoEconomics
Pharmacoeconomics
20
6
10.2165/00019053-200220060-00004
eng
2,002
null
null
null
null
null
[OBJECTIVE] To investigate the effect of changes in body mass index (BMI) on health state preferences (HSP). [DESIGN] Multiple regression analysis on pooled data from a clinical study, predicting final HSP as a function of changes in BMI and initial HSP, controlling for age and gender. Subgroup analyses according to cl...
null
0.787
124
Health Policy; Pharmacology; Public Health, Environmental and Occupational Health
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,002
12,051,879
Evaluation of prognostic factors and treatment modalities in ovarian cancer patients with brain metastases.
Gynecologic oncology
Gynecol Oncol
85
3
10.1006/gyno.2002.6653
eng
2,002
6
null
null
null
null
[OBJECTIVE] The objective of this study is to evaluate the impact of different clinical variables and treatment modalities on survival in patients with brain metastases from ovarian carcinoma. [METHODS] Methods included: (1) retrospective chart review of all patients with ovarian cancer and brain metastases from 1986 t...
null
0.994
192
Obstetrics and Gynecology; Oncology
Medicine
2,002
12,051,500
Characteristics of free-roaming cats and their caretakers.
Journal of the American Veterinary Medical Association
J Am Vet Med Assoc
220
11
10.2460/javma.2002.220.1627
eng
2,002
6
1
null
null
null
[OBJECTIVES] To describe the characteristics of unowned, free-roaming cats and their caretakers who participated in a trap-neuter-return (TNR) program and to determine the effect of the program on free-roaming cat colonies. [DESIGN] Prospective study. [SAMPLE POPULATION] 101 caretakers of 920 unowned, free-roaming cats...
null
0.688
137
Veterinary
Veterinary
2,002
12,051,281
Ocular outcomes in low birth weight premature infants with intraventricular hemorrhage.
Journal of pediatric ophthalmology and strabismus
J Pediatr Ophthalmol Strabismus
39
3
10.3928/0191-3913-20020501-07
eng
2,002
null
null
null
null
null
[PURPOSE] To study ocular outcomes in very low birth weight premature infants with intraventricular hemorrhage. [METHODS] Parents of 490 consecutive very low birth weight (less than 1500 g) premature infants who were discharged from the neonatal intensive care unit of our hospital between 1994 and 1996 were asked to en...
null
0.542
55
Medicine; Ophthalmology; Pediatrics, Perinatology and Child Health
Medicine
2,002
12,051,012
Coronary arteriovenous fistula in pediatric patients: a 17-year institutional experience.
Journal of the Formosan Medical Association = Taiwan yi zhi
J Formos Med Assoc
101
3
null
eng
2,002
3
null
null
null
null
[BACKGROUND AND PURPOSE] Coronary arteriovenous fistula (CAVF) is a rare congenital anomaly in pediatric patients. Its clinical manifestations vary considerably and its long-term outcome is not fully understood. This study sought to determine the natural history and long-term outcome in CAVF patients treated over a 17-...
null
null
null
null
null
null
12,050,986
Predictors of adolescent self-rated health. Analysis of the National Population Health Survey.
Canadian journal of public health = Revue canadienne de sante publique
Can J Public Health
93
3
10.1007/BF03404999
eng
2,002
null
null
null
null
null
[OBJECTIVE] To examine what factors predict adolescents' concepts of their health. [METHODS] The study, based on the longitudinal National Population Health Survey, included 1,493 adolescents who were 12-19 at the time of interview. Sex, age, grade, family structure, income, disability, chronic health problems, social ...
null
null
null
null
null
null
12,050,566
Expression, localization and activity of neutral endopeptidase in cultured cells of benign prostatic hyperplasia and prostate cancer.
The Journal of urology
J Urol
168
1
null
eng
2,002
7
null
null
null
null
[PURPOSE] Neutral endopeptidase is a cell surface enzyme that cleaves and inactivates neuropeptides. Neutral endopeptidase is expressed by prostatic epithelial cells and is thought to have a key role in the growth of androgen independent prostate cancer. In contrast to the encouraging data dealing with neutral endopept...
null
1.629
291
Urology
Medicine
2,002
12,050,548
Follicular large cell lymphoma localized to the testis in children.
The Journal of urology
J Urol
168
1
null
eng
2,002
7
null
null
null
null
[PURPOSE] Primary follicular lymphoma of the testis in childhood is rare with only 6 cases previously reported. We present 3 additional cases. [MATERIALS AND METHODS] We extensively analyzed primary follicular lymphoma of the testis in 3 boys. Clinical data were obtained by reviewing patient charts. [RESULTS] The patie...
null
1.629
291
Urology
Medicine
2,002
12,049,303
Treatment of uterine sarcoma. A survey of 49 patients.
Archives of gynecology and obstetrics
Arch Gynecol Obstet
266
2
10.1007/s004040100222
eng
2,002
4
null
null
null
null
[PURPOSE] Surgery, radiotherapy and chemotherapy are employed in the treatment of uterine sarcoma. We claim to evaluate the role of radiotherapy in the treatment of uterine sarcoma. [PATIENTS AND METHODS] We report a retrospective study of 49 patients with uterine sarcoma treated from 1990-1999 at Masaryk Memorial Canc...
null
0.39
90
Medicine; Obstetrics and Gynecology
Medicine
2,002
12,049,296
A favorable outcome of pregnancies in women with primary and secondary recurrent pregnancy loss associated with antiphospholipid syndrome.
Archives of gynecology and obstetrics
Arch Gynecol Obstet
266
2
10.1007/s004040100179
eng
2,002
4
null
null
null
null
[OBJECTIVE] To study the outcome of pregnancies in women with primary and secondary recurrent pregnancy loss associated with antiphospholipid syndrome treated with the standard treatment regimes including intravenous immunoglobulin (IV Ig). [METHODS] Forty three patients with recurrent pregnancy loss associated with an...
null
0.39
90
Medicine; Obstetrics and Gynecology
Medicine
2,002
12,048,654
Goal attainment scaling in the rehabilitation of patients with lower-extremity amputations: a pilot study.
Archives of physical medicine and rehabilitation
Arch Phys Med Rehabil
83
6
10.1053/apmr.2002.32636
eng
2,002
6
null
null
null
null
[OBJECTIVE] To assess the interrater reliability, construct validity, and responsiveness of Goal Attainment Scaling (GAS) among patients who have had lower-extremity amputations. [DESIGN] Pilot study comparing GAS with 2 functional measures with established reliability, validity, and responsiveness values. [SETTING] Re...
null
1.038
225
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science
Health Professions; Medicine
2,002
12,047,306
Longitudinal umbilical vein blood flow changes in normal and growth-retarded fetuses.
Acta obstetricia et gynecologica Scandinavica
Acta Obstet Gynecol Scand
81
6
null
eng
2,002
6
null
null
null
null
[OBJECTIVE] To explore whether the umbilical vein blood flow of growth-retarded fetuses with normal Doppler parameters changes over time differently to that of normally grown fetuses. [METHODS] Fifteen consecutive women whose fetus was diagnosed to be growth restricted were compared with 30 women whose fetus was normal...
null
0.735
126
Medicine; Obstetrics and Gynecology
Medicine
2,002
12,046,092
Presence and density of common bile duct microlithiasis in acute biliary pancreatitis.
World journal of gastroenterology
World J Gastroenterol
8
3
10.3748/wjg.v8.i3.558
eng
2,002
6
null
null
null
null
[AIM] Common bile duct microlithiasis (CBDM) is found in majority of patients with acute biliary pancreatitis (ABP) and no CBD stones in fluoroscopy during urgent ERCP. It is unclear, however, weather CBDM is a cause or the result of the disease. This prospective study was done to investigate the presence and density o...
null
null
null
null
null
null
12,045,885
Postmenopausal hormone use and lens opacities.
Ophthalmic epidemiology
Ophthalmic Epidemiol
9
3
10.1076/opep.9.3.179.1513
eng
2,002
7
null
null
null
null
[PURPOSE] Women are at higher risk for age-related cataract than men, and it has been hypothesized that this difference is due in part to gender-related hormonal differences. [METHODS] We investigated the association between postmenopausal hormone use and lens opacities in a population of 480 postmenopausal women from ...
null
0.569
78
Ophthalmology; Epidemiology
Medicine
2,002
12,045,646
Validation of new trauma triage rules for trauma attending response to the emergency department.
The Journal of trauma
J Trauma
52
6
10.1097/00005373-200206000-00022
eng
2,002
6
null
null
null
null
[INTRODUCTION] The American College of Surgeons Committee on Trauma has suggested triage criteria for the immediate attendance of a trauma surgeon to an injured patient in the emergency department. This study validates the accuracy of these criteria in identifying high-risk trauma patients and assesses the impact of tr...
null
null
null
null
null
null
12,045,314
Service use among patients with schizophrenia in psychoeducational multiple-family group treatment.
Psychiatric services (Washington, D.C.)
Psychiatr Serv
53
6
10.1176/appi.ps.53.6.749
eng
2,002
6
null
null
null
null
[OBJECTIVES] Outpatient and inpatient mental health service outcomes for outpatients with schizophrenia or schizoaffective disorder who received psychoeducational multiple-family group treatment were compared with outcomes for similar patients who received standard care. [METHODS] A total of 106 outpatients with schizo...
null
0.936
174
Medicine; Psychiatry and Mental Health
Medicine
2,002
12,045,169
Effects of cholesterol and inflammation-sensitive plasma proteins on incidence of myocardial infarction and stroke in men.
Circulation
Circulation
105
22
10.1161/01.cir.0000017327.69909.ff
eng
2,002
6
4
null
null
null
[BACKGROUND] Although cholesterol is a major cardiovascular risk factor, its association with stroke remains controversial. This study explored whether the cholesterol-related incidence of stroke and myocardial infarction is modified by plasma markers of inflammation in a large, population-based cohort with a long foll...
null
5.233
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,002
12,045,167
Effects of xanthine oxidase inhibition with allopurinol on endothelial function and peripheral blood flow in hyperuricemic patients with chronic heart failure: results from 2 placebo-controlled studies.
Circulation
Circulation
105
22
10.1161/01.cir.0000017502.58595.ed
eng
2,002
6
4
null
null
null
[BACKGROUND] In patients with chronic heart failure (CHF), hyperuricemia is a common finding and is associated with reduced vasodilator capacity and impaired peripheral blood flow. It has been suggested that the causal link of this association is increased xanthine oxidase (XO)-derived oxygen free radical production an...
null
5.233
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,002
12,045,084
Low prevalence of Chlamydia trachomatis by urinary ligase chain reaction in women patients in the emergency department.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
Acad Emerg Med
9
6
10.1111/j.1553-2712.2002.tb02308.x
eng
2,002
6
null
null
null
null
[UNLABELLED] Recent studies suggest that women with acute urethral syndrome or abdominal pain, presenting to emergency departments (EDs), have a high prevalence of Chlamydia trachomatis. [OBJECTIVES] To estimate the prevalence of C. trachomatis in women presenting to an ED and to see whether those with dysuria or abdom...
null
0.867
148
Emergency Medicine; Medicine
Medicine
2,002
12,045,060
Long-term outcome of keratolimbal allograft with or without penetrating keratoplasty for total limbal stem cell deficiency.
Ophthalmology
Ophthalmology
109
6
10.1016/s0161-6420(02)00960-0
eng
2,002
6
null
null
null
null
[PURPOSE] To evaluate the long-term outcome of ocular surface reconstruction, including keratolimbal allograft (KLAL) and amniotic membrane transplantation (AMT) with or without penetrating keratoplasty (PKP), in patients with nonambulatory vision secondary to total limbal stem cell deficiency (LSCD). [DESIGN] Retrospe...
null
2.479
297
Ophthalmology
Medicine
2,002
12,044,339
The levels of circulatory cell free fetal DNA in maternal plasma are elevated prior to the onset of preeclampsia.
Hypertension in pregnancy
Hypertens Pregnancy
21
1
10.1081/PRG-120002911
eng
2,002
null
null
null
null
null
[OBJECTIVE] Elevations in cell free fetal DNA has previously been determined in pregnancies affected by preeclampsia. A recent report has indicated that cell free fetal DNA concentrations are elevated early in pregnancy before disease onset. As we have recently performed a prospective study to examine fetal cell traffi...
null
0.748
55
Internal Medicine; Obstetrics and Gynecology
Medicine
2,002
12,044,333
Vascular maternal reactivity and neonatal size in normal pregnancy.
Hypertension in pregnancy
Hypertens Pregnancy
20
3
10.1081/PRG-100107827
eng
2,001
null
null
null
null
null
[OBJECTIVE] The purpose of the present study was to determine the associations of cold pressor test (CPT) cardiovascular reactivity with gestational age at birth and neonatal size in normotensive pregnant women. [METHODS] Seventy (70) healthy pregnant women were enrolled. The CPT consisted of introducing the patients' ...
null
0.464
55
Internal Medicine; Obstetrics and Gynecology
Medicine
2,001
12,044,117
Hypertension and its risk factors in tea garden workers of Assam.
The National medical journal of India
Natl Med J India
15
2
null
eng
2,002
null
null
null
null
null
[BACKGROUND] Hypertension is emerging as a major public health problem in India. The diversity and heterogeneity of distribution of the population makes it difficult to arrive at the precise prevalence. In Assam, reports from hospitals in tea gardens reveal a high prevalence of hypertension among workers in tea gardens...
null
null
null
null
null
null
12,044,000
Ethnic and gender differences in the use of coronary artery revascularisation procedures in New Zealand.
The New Zealand medical journal
N Z Med J
115
1152
null
eng
2,002
4
26
null
null
null
[AIMS] To examine ethnic and gender variations in the use of coronary artery revascularisation procedures in New Zealand and to determine whether the introduction of priority scores affected intervention trends. [METHODS] Analysis of the National Minimum Database for coronary artery bypass graft (CABG) and percutaneous...
null
0.324
60
Medicine
Medicine
2,002
12,043,559
The presence of medical students in practice consultations. Rates of patient consent.
Australian family physician
Aust Fam Physician
31
5
null
eng
2,002
5
null
null
null
null
[OBJECTIVE] To measure the frequency of nonconsent encountered by medical students and describe the influence of gender. [METHOD] An observational study of general practice teaching consultations. [SUBJECTS] 63 students (40% female), 67 general practitioners (30% female), and 2572 patients (56% female). [OUTCOME] 3.4% ...
null
null
null
null
null
null
12,042,690
Assessing inpatient pulmonary rehabilitation using the patient's view of outcome.
Journal of cardiopulmonary rehabilitation
J Cardiopulm Rehabil
22
3
10.1097/00008483-200205000-00013
eng
2,002
null
null
null
null
null
[PURPOSE] Assessment of the patient's view of outcome should complement standardized evaluation methods, especially in multi-intervention rehabilitation programs. Assessment of individualized outcomes has not been used previously in pulmonary rehabilitation studies. Therefore, the authors developed a method for assessi...
null
null
null
null
null
null
12,042,228
Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years. Report from the Avon Longitudinal Study of Parents and Children.
The British journal of psychiatry : the journal of mental science
Br J Psychiatry
180
null
10.1192/bjp.180.6.502
eng
2,002
6
null
null
null
null
[BACKGROUND] Animal experiments suggest that maternal stress and anxiety during pregnancy have long-term effects on the behaviour of the offspring. [AIMS] To test the hypothesis that antenatal maternal anxiety predicts behavioural problems at age 4 years. [METHOD] Data were collected on multiple antenatal and postnatal...
null
2.874
264
Medicine; Psychiatry and Mental Health
Medicine
2,002
12,042,102
Is measurement of stone surface area necessary for SWL treatment of nonstaghorn calculi?
Journal of endourology
J Endourol
16
4
10.1089/089277902753752151
eng
2,002
5
null
null
null
null
[BACKGROUND AND PURPOSE] The size of urinary tract stones is usually assessed by the longest diameter (LD) alone. Logically, however, two-dimensional measurement of the stone surface area (SSA) susceptible to shockwaves would give more useful information for the planning of treatment by extracorporeal shockwave lithotr...
null
0.744
107
Medicine; Urology
Medicine
2,002
12,150,513
Risk of injury to the external branch of the superior laryngeal nerve in thyroidectomy.
The Laryngoscope
Laryngoscope
112
4
10.1097/00005537-200204000-00006
eng
2,002
4
null
null
null
null
[OBJECTIVE] To establish in the Mexican population with thyroid disease the risk of injury to the external branch of the superior laryngeal nerve (EBSLN) based on its anatomical position. [STUDY DESIGN] Non-randomized comparative clinical trial. [METHODS] Seventy-three patients subjected to thyroidectomy because of thy...
null
1.395
183
Otorhinolaryngology
Medicine
2,002
12,150,176
Use of lidocaine-prilocaine patch to decrease intramuscular injection pain does not adversely affect the antibody response to diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b conjugate and hepatitis B vaccines in infants from birth to six months of age.
The Pediatric infectious disease journal
Pediatr Infect Dis J
21
5
10.1097/00006454-200205000-00010
eng
2,002
5
null
null
null
null
[BACKGROUND] Topical lidocaine-prilocaine (EMLA) effectively decreases the pain associated with minor procedures including immunization, although the effect on the antibody response to diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae type b conjugate (DTaP-IPV-Hib) and hepatitis B va...
null
1.243
160
Infectious Diseases; Microbiology; Pediatrics, Perinatology and Child Health
Medicine
2,002
12,150,168
Observed costs and health care use of children in a randomized controlled trial of pneumococcal conjugate vaccine.
The Pediatric infectious disease journal
Pediatr Infect Dis J
21
5
10.1097/00006454-200205000-00002
eng
2,002
5
null
null
null
null
[BACKGROUND] Pneumococcal conjugate vaccine for infants has recently been found to be effective for prevention of meningitis, bacteremia, pneumonia and otitis media, but it is more costly than previously introduced vaccines. [AIM] We sought to determine the savings in medical costs through 36 months of life attributabl...
null
1.243
160
Infectious Diseases; Microbiology; Pediatrics, Perinatology and Child Health
Medicine
2,002
12,149,570
Temporal morphogenesis of herpes simplex virus type 1-infected and brefeldin A-treated human fibroblasts.
Molecular medicine (Cambridge, Mass.)
Mol Med
8
4
null
eng
2,002
4
null
null
null
null
[BACKGROUND] Insights in the herpesvirus-cell interactions are of general cell biology interest, especially to studies of intracellular transport, and of considerable significance in the efforts to generate drugs, vaccines, and gene therapy. However, the pathway of virus particle egress and maturation is a contentious ...
null
1.76
136
Genetics; Genetics; Molecular Medicine; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
12,149,134
Setting of graded levels of a protein in yeast by a t-degron technique as applied to phosphoglycerate mutase.
BMC genetics
BMC Genet
3
null
10.1186/1471-2156-3-13
eng
2,002
7
30
2,002
7
30
[BACKGROUND] Setting of graded levels of a protein for in vivo studies by controlled gene expression has inconveniences, and we here explore the use of the t-degron technique instead. [RESULTS] In a yeast t-degron (ubiquitin-argDHFR(ts))- phosphoglycerate mutase (GPM1) fusion strain, increasing periods of exposure to t...
null
null
null
null
null
null
12,148,110
Response to recombinant hepatitis B vaccine in children and adolescents with chronic renal failure.
American journal of kidney diseases : the official journal of the National Kidney Foundation
Am J Kidney Dis
40
2
10.1053/ajkd.2002.34521
eng
2,002
8
null
null
null
null
[BACKGROUND] Diminished antibody responses to the dosage of hepatitis B (HB) vaccine indicated for healthy adults has led to a greater dosage recommendation (40 microg of HB surface antigen [HBsAg]) for adults with chronic renal failure (CRF), but an appropriate dosage for children with CRF has not been established. [M...
null
1.434
249
Nephrology
Medicine
2,002
12,147,804
Fluvastatin prevents development of arterial stiffness in haemodialysis patients with type 2 diabetes mellitus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Nephrol Dial Transplant
17
8
10.1093/ndt/17.8.1513
eng
2,002
8
null
null
null
null
[BACKGROUND] Arterial stiffness assessed by pulse wave velocity (PWV) predicts all-cause and cardiovascular mortality in diabetic patients with end-stage renal disease. We studied the preventive effects of a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, fluvastatin, on arterial PWV values in this populatio...
null
0.833
203
Medicine; Nephrology; Transplantation
Medicine
2,002
12,147,785
Reduced bone mass in children with idiopathic hypercalciuria and in their asymptomatic mothers.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Nephrol Dial Transplant
17
8
10.1093/ndt/17.8.1396
eng
2,002
8
null
null
null
null
[BACKGROUND] Patients with nephrolithiasis and idiopathic hypercalciuria (IH) may exhibit reduced bone mineral density (BMD). Most studies measuring BMD in IH patients employing dual-energy X-ray absorptiometry (DEXA) have been performed in adults, and no study has been conducted in North-American children. Optimal bon...
null
0.833
203
Medicine; Nephrology; Transplantation
Medicine
2,002
12,147,606
Human optic nerve head astrocytes as a target for endothelin-1.
Investigative ophthalmology & visual science
Invest Ophthalmol Vis Sci
43
8
null
eng
2,002
8
null
null
null
null
[PURPOSE] To determine whether human optic nerve head astrocytes (hONAs) are target cells for the actions of endothelin (ET)-1, a potent vasoactive peptide, by causing astrocyte proliferation, as occurs in glaucomatous optic nerve heads. ET-1 levels are elevated in glaucomatous eyes, and administration of ET-1 to the r...
null
null
null
null
null
null
12,147,593
Laminin alpha5 chain adhesion and signaling in conjunctival epithelial cells.
Investigative ophthalmology & visual science
Invest Ophthalmol Vis Sci
43
8
null
eng
2,002
8
null
null
null
null
[PURPOSE] To identify peptides of the LG4 module of the laminin alpha5 chain that mediate human conjunctival epithelial cell adhesion to the laminin-10 isoform. [METHODS] A peptide corresponding to a major heparin- and cell-binding domain of the LG4 module of the laminin alpha5 chain was analyzed. The attachment of con...
null
null
null
null
null
null
12,147,562
Aerobic training in the 'oldest old': the effect of 24 weeks of training.
Age and ageing
Age Ageing
31
4
10.1093/ageing/31.4.255
eng
2,002
7
null
null
null
null
[OBJECTIVE] to determine the effects of aerobic training on the maximal aerobic power of healthy, very elderly people. [DESIGN] a 12-week control period followed by 24 weeks of progressive, weight bearing, aerobic training. [SUBJECTS] 26 men and women aged 79 to 91 years conforming to pre-determined health criteria. [M...
null
0.599
175
Aging; Geriatrics and Gerontology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
12,147,110
Patients with a longer duration of symptoms of acute asthma are more likely to require admission to hospital.
Emergency medicine (Fremantle, W.A.)
Emerg Med (Fremantle)
14
2
10.1046/j.1442-2026.2002.00308.x
eng
2,002
6
null
null
null
null
[OBJECTIVE] To determine whether, for patients with moderate or severe asthma presenting to emergency departments, there is a difference in need for hospitalization between those with a duration of symptoms less than 6 h and those with a longer duration of symptoms. [METHODS] This prospective, observational study inves...
null
null
null
null
null
null
12,147,034
Validation of the NucliSens Extractor combined with the AmpliScreen HIV version 1.5 and HCV version 2.0 test for application in NAT minipool screening.
Transfusion
Transfusion
42
6
10.1046/j.1537-2995.2002.00113.x
eng
2,002
6
null
null
null
null
[BACKGROUND] Routine HCV NAT minipool screening (48 donations) of all blood donations was implemented in July 1999 and was combined with HIV NAT in November 2000. This report describes the validation of the NAT methods and the results of quality control testing. [STUDY DESIGN AND METHODS] Nucleic acid was extracted fro...
null
0.611
153
Hematology; Immunology and Allergy; Immunology
Immunology and Microbiology; Medicine
2,002
12,147,027
The United Kingdom National External Quality Assessment Scheme gating and standardization strategy for use in residual WBC counting of WBC-reduced blood components.
Transfusion
Transfusion
42
6
10.1046/j.1537-2995.2002.00116.x
eng
2,002
6
null
null
null
null
[BACKGROUND] Major causes of interlaboratory variation in low-level WBC counting are the gating strategies and staining methods employed. To overcome these limitations, a stable low-level WBC control preparation (termed daily run control [DRC]) was developed that when coupled with a new gating strategy will enable inte...
null
0.611
153
Hematology; Immunology and Allergy; Immunology
Immunology and Microbiology; Medicine
2,002
12,146,987
Multiple-gland disease in primary hyperparathyroidism: a function of operative approach?
Archives of surgery (Chicago, Ill. : 1960)
Arch Surg
137
8
10.1001/archsurg.137.8.896
eng
2,002
8
null
null
null
null
[HYPOTHESIS] The approach to surgery for primary hyperparathyroidism (PHPT) is controversial. To determine whether routine bilateral neck exploration increases the detection of multiple-gland disease compared with a focused unilateral approach, we compared the incidence of single vs multiple-gland disease in patients u...
null
null
null
null
null
null
12,146,843
Acromegaly and cancer risk: a cohort study in Sweden and Denmark.
Cancer causes & control : CCC
Cancer Causes Control
13
5
10.1023/a:1015713732717
eng
2,002
6
null
null
null
null
[OBJECTIVE] Several studies have suggested that patients with acromegaly have an increased risk of benign and malignant neoplasms, especially of the colon. To further investigate this relationship we evaluated cancer risk in population-based cohorts of acromegaly patients in Sweden and Denmark. [METHODS] Nationwide reg...
null
null
null
null
null
null
12,146,527
Effect of polylactide/glycolide (PLGA) membranes loaded with metronidazole on periodontal regeneration following guided tissue regeneration in dogs.
Journal of periodontology
J Periodontol
73
7
10.1902/jop.2002.73.7.694
eng
2,002
7
null
null
null
null
[BACKGROUND] Bioabsorbable membranes have been successfully used for guided tissue regeneration (GTR) and local delivery systems because they are biocompatible and do not require second surgery for removal. Several studies have demonstrated that metronidazole, when applied topically, produced immediate effects on micro...
null
0.932
186
Periodontics
Dentistry
2,002
12,146,032
Fine needle aspiration cytology of bursal cyst.
Acta cytologica
Acta Cytol
46
4
10.1159/000326977
eng
2,002
null
null
null
null
null
[OBJECTIVE] To evaluate the cytomorphology of bursal cyst and assess the efficacy of aspiration cytology in its diagnosis and treatment. [STUDY DESIGN] Nineteen cases of bursal cyst seen over four years were studied. Material was obtained by fine needle aspiration. The smears were stained with May-Grünwald-Giemsa stain...
null
0.502
67
Medicine; Histology; Pathology and Forensic Medicine
Medicine
2,002
12,145,224
Survival in patients with type 2 diabetes in a Swedish community: skaraborg hypertension and diabetes project.
Diabetes care
Diabetes Care
25
8
10.2337/diacare.25.8.1297
eng
2,002
8
null
null
null
null
[OBJECTIVE] To explore risk factors for all-cause mortality in patients with type 2 diabetes treated in primary care. [RESEARCH DESIGN AND METHODS] A prospective population-based study of 400 patients with type 2 diabetes who consecutively completed an annual checkup in primary care in Skara, Sweden, during 1992-1993. ...
null
2.924
433
Advanced and Specialized Nursing; Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine; Nursing
2,002
12,144,987
Life-course socioeconomic and behavioral influences on cardiovascular disease mortality: the collaborative study.
American journal of public health
Am J Public Health
92
8
10.2105/ajph.92.8.1295
eng
2,002
8
null
null
null
null
[OBJECTIVES] This study sought to demonstrate life-course influences on cardiovascular disease (CVD). [METHODS] Data were derived from a prospective observational study in which the main outcome measure was death resulting from CVD. [RESULTS] Combining 4 socioeconomic and behavioral risk indicators into a measure of li...
null
2.167
321
Public Health, Environmental and Occupational Health
Medicine
2,002
12,144,073
Effect of a second-year primary care preceptorship on medical students' career plans.
Southern medical journal
South Med J
95
7
null
eng
2,002
7
null
null
null
null
[BACKGROUND] Preceptorships with community physicians have been incorporated into medical curricula to foster interest in generalist careers. An evaluation of our preceptorship program was undertaken to determine this influence. [METHODS] Students were asked about career interests before and after a second-year communi...
null
null
null
null
null
null
12,142,388
Measurement of the noncomplexed free fraction of tissue inhibitor of metalloproteinases 1 in plasma by immunoassay.
Clinical chemistry
Clin Chem
48
8
null
eng
2,002
8
null
null
null
null
[BACKGROUND] We previously found differences in total concentrations of tissue inhibitor of metalloproteinases 1 (TIMP-1) in plasma from donors and cancer patients. Because TIMP-1 can exist in more than one molecular form, a new immunoassay to specifically detect free TIMP-1 was developed and concentrations were determ...
null
1.355
248
Biochemistry; Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology; Medicine
2,002
12,141,621
Research use of linked health data--a best practice protocol.
Australian and New Zealand journal of public health
Aust N Z J Public Health
26
3
10.1111/j.1467-842x.2002.tb00682.x
eng
2,002
null
null
null
null
null
[OBJECTIVE] This article outlines a protocol for facilitating access to administrative data for the purpose of health services research, when these data are sourced from multiple organisations. This approach is designed to promote confidence in the community and among data custodians that there are benefits of linked h...
null
0.537
92
Public Health, Environmental and Occupational Health
Medicine
2,002