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12,141,589 | The prevalence of foot problems in older women: a cause for concern. | Journal of public health medicine | J Public Health Med | 24 | 2 | 10.1093/pubmed/24.2.77 | eng | 2,002 | 6 | null | null | null | null | [BACKGROUND] Painful feet are an extremely common problem amongst older women. Such problems increase the risk of falls and hamper mobility. The aetiology of painful and deformed feet is poorly understood. [METHODS] Data were obtained during a pilot case-control study about past high heel usage in women, in relation to... | null | null | null | null | null | null |
12,140,641 | Virtual reality as a metric for the assessment of laparoscopic psychomotor skills. Learning curves and reliability measures. | Surgical endoscopy | Surg Endosc | 16 | 12 | 10.1007/s00464-001-8215-6 | eng | 2,002 | 12 | null | 2,002 | 7 | 29 | [BACKGROUND] The objective assessment of the psychomotor skills of surgeons is now a priority; however, this is a difficult task because of measurement difficulties associated with the assessment of surgery in vivo. In this study, virtual reality (VR) was used to overcome these problems. [METHODS] Twelve experienced (>... | null | 1.035 | 178 | Surgery | Medicine | 2,002 |
12,140,639 | Laparoscopic repair of recurrent inguinal hernia. | Surgical endoscopy | Surg Endosc | 16 | 12 | 10.1007/s00464-002-8906-7 | eng | 2,002 | 12 | null | 2,002 | 7 | 29 | [BACKGROUND] Laparoscopic repair is becoming a popular treatment for recurrent inguinal hernia. The true long-term recurrence of this method is unknown. [METHODS] Patients who underwent laparoscopic recurrent inguinal hernia repair at our institution were followed up. Patients were interviewed by phone at least 6 month... | null | 1.035 | 178 | Surgery | Medicine | 2,002 |
12,140,469 | Acne therapy: a methodologic review. | Journal of the American Academy of Dermatology | J Am Acad Dermatol | 47 | 2 | 10.1067/mjd.2002.120912 | eng | 2,002 | 8 | null | null | null | null | [BACKGROUND] Acne is a very common problem with significant physical and psychological morbidity. The evidence basis for its treatment had not been systematically reviewed. Therefore, we performed an evidence review to provide researchers a basis for further studies, and to provide clinicians the background needed to i... | null | 1.349 | 256 | Dermatology | Medicine | 2,002 |
12,140,049 | Graft-vs-host-disease-associated conjunctival chemosis and central serous chorioretinopathy after bone marrow transplant. | American journal of ophthalmology | Am J Ophthalmol | 134 | 2 | 10.1016/s0002-9394(02)01464-2 | eng | 2,002 | 8 | null | null | null | null | [PURPOSE] To describe bilateral conjunctival chemosis and central serous chorioretinopathy in a patient with graft-vs-host disease after bone marrow transplant. [DESIGN] Interventional case report. [METHODS] A 45-year-old Chinese woman developed blurring of vision 16 days after bone marrow transplant for multiple myelo... | null | 1.784 | 221 | Ophthalmology | Medicine | 2,002 |
12,140,048 | Histopathologic study of variation in severity of retinitis pigmentosa due to the dominant rhodopsin mutation Pro23His. | American journal of ophthalmology | Am J Ophthalmol | 134 | 2 | 10.1016/s0002-9394(02)01545-3 | eng | 2,002 | 8 | null | null | null | null | [PURPOSE] To compare histopathologic findings in an autopsy eye of an 87-year-old woman with retinitis pigmentosa and the rhodopsin mutation Pro23His with findings in an autopsy eye of a 77-year-old female relative (first cousin) with retinitis pigmentosa and the same mutation. [DESIGN] Histopathologic study. [METHODS]... | null | 1.784 | 221 | Ophthalmology | Medicine | 2,002 |
12,139,639 | Actin-binding protein fascin expression in skin neoplasia. | Journal of cutaneous pathology | J Cutan Pathol | 29 | 7 | 10.1034/j.1600-0560.2002.290708.x | eng | 2,002 | 8 | null | null | null | null | [BACKGROUND] Fascin containing actin bundles provide mechanical support to cellular protrusions and stress fibers. In cancers, some malignant cells (e.g. subsets of breast and ovarian carcinomas) express fascin. In skin cancer, the role of fascin is unknown. [METHODS] Cases of 61 keratocytic neoplasms, 35 melanocytic n... | null | 0.708 | 89 | Dermatology; Histology; Pathology and Forensic Medicine | Medicine | 2,002 |
12,139,638 | h-Caldesmon as a specific marker of smooth muscle cell differentiation in some soft tissue tumors of the skin. | Journal of cutaneous pathology | J Cutan Pathol | 29 | 7 | 10.1034/j.1600-0560.2002.290707.x | eng | 2,002 | 8 | null | null | null | null | [BACKGROUND] An existing problem in contemporary pathology is the classification and distinction of spindle cell soft tissue tumors of the skin. Markers such as alpha-smooth muscle actin (alpha-SMA) and desmin, considered specific for smooth muscle cell (SMC), have been shown to be expressed in a variety of fibroblasti... | null | 0.708 | 89 | Dermatology; Histology; Pathology and Forensic Medicine | Medicine | 2,002 |
12,139,233 | Paradigms for primary prevention of ovarian carcinoma. | CA: a cancer journal for clinicians | CA Cancer J Clin | 52 | 4 | 10.3322/canjclin.52.4.216 | eng | 2,002 | null | null | null | null | null | [OBJECTIVE] To provide the clinician with current concepts regarding prevention of ovarian cancer. Specifically, in this review, we provide a rationale for chemoprevention of ovarian cancer, a description of promising chemopreventive agents, and an overview of surgical strategies used in the prevention of ovarian cance... | null | null | null | null | null | null |
12,138,990 | Minor tumour shrinkage in nonfunctioning pituitary adenomas by long-term treatment with the dopamine agonist cabergoline. | Pituitary | Pituitary | 4 | 3 | 10.1023/a:1015366923810 | eng | 2,001 | 8 | null | null | null | null | [OBJECTIVE] The purpose of this study was to define safety and efficacy of medical therapy in the treatment of nonfunctioning pituitary tumours. [DESIGN] We studied thirteen patients with a clinically nonfunctioning pituitary macroadenoma for response to cabergoline treatment for 1 year. Twelve/13 patients were already... | null | 0.296 | 84 | Endocrinology; Endocrinology, Diabetes and Metabolism | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
12,137,876 | Preventing adverse obstetric outcomes in women with genetic thrombophilia. | Fertility and sterility | Fertil Steril | 78 | 2 | 10.1016/s0015-0282(02)03222-3 | eng | 2,002 | 8 | null | null | null | null | [OBJECTIVE] To improve fetomaternal outcomes in women with obstetric complications and inherited causes of thrombophilia. [DESIGN] Clinical trial. [SETTING] Thrombophilic women with previous unexplained adverse outcomes. [PATIENT(S)] Twenty-five women with previous severe obstetric complications were treated during and... | null | 1.385 | 252 | Obstetrics and Gynecology; Reproductive Medicine | Medicine | 2,002 |
12,137,256 | Auditing of clinical research ethics in a children's and women's academic hospital. | Clinical and investigative medicine. Medecine clinique et experimentale | Clin Invest Med | 25 | 3 | null | eng | 2,002 | 6 | null | null | null | null | [OBJECTIVE] Canadian and international guidelines for research ethics practices have advocated that research ethics boards (REBs) should implement mechanisms to review and monitor human research. Despite this, few Canadian REBs fulfil this expectation. The objective of this report is to summarize the results of 6 audit... | Biomedical and Behavioral Research; Dalhousie University; Empirical Approach | null | null | null | null | null |
12,137,223 | Deep tendon reflexes: a study of quantitative methods. | The journal of spinal cord medicine | J Spinal Cord Med | 25 | 2 | 10.1080/10790268.2002.11753608 | eng | 2,002 | null | null | null | null | null | [OBJECTIVE] The deep tendon reflex (DTR) is routinely used by clinicians to evaluate the nervous system. Depressed and hyperactive DTRs suggest peripheral and central nervous system compromise, respectively. Limitations of DTRs are: qualitative nature of the assessments based upon subjective grading, and limited inter-... | null | 0.479 | 81 | Neurology | Medicine | 2,002 |
12,136,368 | Cimicifuga racemosa: a systematic review of its clinical efficacy. | European journal of clinical pharmacology | Eur J Clin Pharmacol | 58 | 4 | 10.1007/s00228-002-0457-2 | eng | 2,002 | 7 | null | 2,002 | 6 | 7 | [BACKGROUND] Cimicifuga racemosa has long been advocated as an alternative to hormone-replacement therapy. However, recent experimental studies and a clinical trial have raised some questions on its utility. The aim of this systematic review is principally to summarise the trial evidence regarding the efficacy of C. ra... | null | 0.622 | 126 | Medicine; Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,002 |
12,135,684 | Delayed administration of carrier marrow can decrease competition on donor stem cells during engraftment and maintain radioprotection of the host. | Experimental hematology | Exp Hematol | 30 | 7 | 10.1016/s0301-472x(02)00834-2 | eng | 2,002 | 7 | null | null | null | null | [OBJECTIVE] The goal of this study was to determine if competitive pressure was placed on hematopoietic stem cells (HSC) by a coinjected "carrier" population that maintains short-term survival of the host. Our hypothesis was that delayed introduction of "carrier" cells would increase engraftment of donor HSC. [MATERIAL... | null | 1.379 | 131 | Cancer Research; Hematology; Cell Biology; Genetics; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
12,135,593 | Limited effects of micronutrient supplementation on strength and physical function after abdominal aortic aneurysmectomy. | Clinical nutrition (Edinburgh, Scotland) | Clin Nutr | 21 | 4 | 10.1054/clnu.2002.0550 | eng | 2,002 | 8 | null | null | null | null | [BACKGROUND] Tissue injury following ischemia-reperfusion is mediated in part by free oxygen radicals. We hypothesized that perioperative micronutrient supplementation would augment antioxidant defenses, minimize muscle injury, and minimize postoperative decreases in muscle strength and physical function following abdo... | null | 0.468 | 183 | Critical Care and Intensive Care Medicine; Nutrition and Dietetics | Medicine; Nursing | 2,002 |
12,133,534 | Follow-up of coronary artery lesions caused by Kawasaki disease and the value of coronary angiography. | Chinese medical journal | Chin Med J (Engl) | 115 | 5 | null | eng | 2,002 | 5 | null | null | null | null | [OBJECTIVE] To investigate the course of coronary artery lesions caused by Kawasaki disease, and the value of coronary angiography (CAG) and two-dimensional echocardiography (2-D Echo) in the evaluation and follow-up of coronary artery lesions. [METHODS] Eighty seven patients with coronary artery lesions caused by Kawa... | null | 0.143 | 84 | Medicine | Medicine | 2,002 |
12,133,302 | Protective immunity induced by the anti-idiotypic monoclonal antibody NP30 of Schistosoma japonicum. | Chinese medical journal | Chin Med J (Engl) | 115 | 4 | null | eng | 2,002 | 4 | null | null | null | null | [OBJECTIVE] To investigate the protective immunity induced by the anti-idiotypic monoclonal antibody NP30 of Schistosoma japonicum in mice. [METHODS] An orthogonal table L(16) (4 x 2(12)) was selected as the experimental design. Eight-week-old Kunming outbred mice (male and female) were randomly divided into 16 experim... | null | 0.143 | 84 | Medicine | Medicine | 2,002 |
12,133,159 | Preferences for patient cost sharing among medicare beneficiaries after HMO plan withdrawals. | Journal of general internal medicine | J Gen Intern Med | 17 | 6 | 10.1046/j.1525-1497.2002.10710.x | eng | 2,002 | 6 | null | null | null | null | [OBJECTIVE] To assess Medicare beneficiaries' willingness to cost share in order to minimize disruptions in coverage from HMO plan withdrawals. [DESIGN] Cross-sectional survey of Medicare beneficiaries from February 1999 to March 1999. [SETTING] Ten U.S. counties with the highest HMO plan withdrawal rates. [PATIENTS/PA... | null | 1.794 | 224 | Internal Medicine | Medicine | 2,002 |
12,133,075 | An oxalate-binding protein with crystal growth promoter activity from human kidney stone matrix. | BJU international | BJU Int | 90 | 3 | 10.1046/j.1464-410x.2002.02849.x | eng | 2,002 | 8 | null | null | null | null | [OBJECTIVE] To fractionate renal-stone matrix proteins, identify the presence of oxalate-binding protein and assess its effect in a calcium oxalate (CaOx) crystal growth system. [MATERIALS AND METHODS] Proteins were isolated from the matrix of kidney stones containing CaOx as the major constituent, using EDTA as a demi... | null | 0.864 | 174 | Urology | Medicine | 2,002 |
12,133,071 | Intestinal and renal handling of oxalate in magnesium-deficient rats. Evaluation of intestinal in vivo 14C-oxalate perfusion. | BJU international | BJU Int | 90 | 3 | 10.1046/j.1464-410x.2002.02811.x | eng | 2,002 | 8 | null | null | null | null | [OBJECTIVE] To clarify in vivo, using isolated small intestinal loops perfused with radioactive 14C-oxalate, whether intestinal hyperabsorption or reduced secretion is important in magnesium deficiency (MgD), as this is a potential cause of calcium oxalate urolithiasis. [MATERIALS AND METHODS] Twenty-four Sprague-Dawle... | null | 0.864 | 174 | Urology | Medicine | 2,002 |
12,132,605 | Clinical effectiveness research in managed-care systems: lessons from the Pediatric Asthma Care PORT. Patient Outcomes Research Team. | Health services research | Health Serv Res | 37 | 3 | 10.1111/1475-6773.00048 | eng | 2,002 | 6 | null | null | null | null | [OBJECTIVE] To highlight the unique challenges of evaluative research on practice behavior change in the "real world" settings of contemporary managed-care organizations, using the experience of the Pediatric Asthma Care PORT (Patient Outcomes Research Team). [STUDY SETTING] The Pediatric Asthma Care PORT is a five-yea... | null | 1.722 | 149 | Health Policy | Medicine | 2,002 |
12,132,520 | Clinical heterogeneity in dysferlinopathy. | Internal medicine (Tokyo, Japan) | Intern Med | 41 | 7 | 10.2169/internalmedicine.41.532 | eng | 2,002 | 7 | null | null | null | null | [OBJECTIVE] To clarify the clinical heterogeneity and genotype-phenotype correlation in dysferlinopathy. [METHODS] We evaluated clinical parameters of 74 dysferlinopathy patients with known dysferlin gene mutations who were previously reported in the literature. [RESULTS] The age at onset varied from 12 to 59 years (me... | null | 0.28 | 83 | Internal Medicine; Medicine | Medicine | 2,002 |
12,131,932 | Stereotactic fibrinolysis of spontaneous intracerebral hematoma using infusion of recombinant tissue plasminogen activator. | Arquivos de neuro-psiquiatria | Arq Neuropsiquiatr | 60 | 2-B | 10.1590/s0004-282x2002000300004 | eng | 2,002 | 6 | null | null | null | null | [PURPOSE] The authors present a prospective study on 10 patients with stereotactic infusion of tissue plasminogen activator (rtPA) intraparenchimal hemorrhage. [METHODS] Between 1999 and 2000, 10 patients with deep seated hematomas in the basal ganglia were selected for stereotactic infusion of rtPA and spontaneous clo... | null | 0.197 | 60 | Neurology; Biological Psychiatry | Medicine; Neuroscience | 2,002 |
12,131,530 | Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension. | Journal of hypertension | J Hypertens | 20 | 7 | 10.1097/00004872-200207000-00020 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] Hypertension is a complex trait with an ill-defined genetic predisposition, in which adrenergic mechanisms seem to be involved even at the early stages. Chromogranin A is a pro-hormone stored and released with catecholamines by exocytosis; its fragment catestatin, formed in vivo, inhibits further catechola... | null | 1.441 | 198 | Cardiology and Cardiovascular Medicine; Internal Medicine; Physiology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
12,131,527 | Role of echocardiography and carotid ultrasonography in stratifying risk in patients with essential hypertension: the Assessment of Prognostic Risk Observational Survey. | Journal of hypertension | J Hypertens | 20 | 7 | 10.1097/00004872-200207000-00017 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] Echocardiography and carotid ultrasonography, by providing a more accurate assessment of cardiac and vascular damage related to hypertension, may lead to a more precise stratification of the global cardiovascular risk. However, current guidelines do not recommend systematic use of ultrasound examination of... | null | 1.441 | 198 | Cardiology and Cardiovascular Medicine; Internal Medicine; Physiology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
12,131,309 | Is periprostatic local anesthesia for transrectal ultrasound guided prostate biopsy associated with increased infectious or hemorrhagic complications? A prospective randomized trial. | The Journal of urology | J Urol | 168 | 2 | null | eng | 2,002 | 8 | null | null | null | null | [PURPOSE] Periprostatic local anesthesia for prostate biopsy requires 2 or more extra needle punctures and injection of the local anesthetic through the highly colonized rectum. To our knowledge we report the first prospective randomized trial to assess the infectious or hemorrhagic complications associated with this m... | null | 1.629 | 291 | Urology | Medicine | 2,002 |
12,130,966 | How reliable is the Bispectral Index in critically ill patients? A prospective, comparative, single-blinded observer study. | Critical care medicine | Crit Care Med | 30 | 7 | 10.1097/00003246-200207000-00014 | eng | 2,002 | 7 | null | null | null | null | [OBJECTIVE] To establish a correlation between a reliable subjective measure, the Sedation-Agitation Scale (SAS), and an objective tool, the Bispectral Index (BIS), for monitoring critically ill patients with a decreased level of consciousness. [DESIGN] Prospective, comparative, single-blinded observer study. [SETTING]... | null | 0.982 | 315 | Critical Care and Intensive Care Medicine | Medicine | 2,002 |
12,130,607 | Are inequalities in height underestimated by adult social position? Effects of changing social structure and height selection in a cohort study. | BMJ (Clinical research ed.) | BMJ | 325 | 7356 | 10.1136/bmj.325.7356.131 | eng | 2,002 | 7 | 20 | null | null | null | [OBJECTIVES] To investigate whether changing social structure and social mobility related to height generate (inflate) inequalities in height. [DESIGN] Longitudinal 1958 British birth cohort study. [SETTING] England, Scotland, and Wales. [PARTICIPANTS] 10 176 people born 3-9 March 1958 for whom data were available at a... | null | 1.087 | 519 | Medicine | Medicine | 2,002 |
12,130,464 | MR imaging of the brain in pediatric patients: diagnostic value of HASTE sequences. | AJR. American journal of roentgenology | AJR Am J Roentgenol | 179 | 2 | 10.2214/ajr.179.2.1790509 | eng | 2,002 | 8 | null | null | null | null | [OBJECTIVE] The objective of this study was to determine the diagnostic value of half-Fourier single-shot turbo spin-echo (HASTE) sequences in MR imaging of the brain in pediatric patients. [SUBJECTS AND METHODS] HASTE sequences were performed in 80 infants and children. Two radiologists who were unaware of the patient... | null | null | null | null | null | null |
12,130,463 | Correlation on cine MR imaging of size of adenoid and palatine tonsils with degree of upper airway motion in asymptomatic sedated children. | AJR. American journal of roentgenology | AJR Am J Roentgenol | 179 | 2 | 10.2214/ajr.179.2.1790503 | eng | 2,002 | 8 | null | null | null | null | [OBJECTIVE] The objective of this study was to use MR fluoroscopy to evaluate variations in size of the adenoid and palatine tonsils and the relationship between tonsil enlargement and airway motion dynamics in asymptomatic children during sleep. [SUBJECTS AND METHODS] We performed sagittal midline cine MR imaging (fas... | null | null | null | null | null | null |
12,127,816 | Long-term culture of primary human hepatocytes with preservation of proliferative capacity and differentiated functions. | The Journal of surgical research | J Surg Res | 106 | 1 | 10.1006/jsre.2002.6446 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] The aim of this study was to develop a suitable method for the prolonged culture and maintenance of human hepatocytes with preservation of both proliferative capacity and differentiated functions. [MATERIALS AND METHODS] Primary human hepatocytes were isolated from small pieces of liver tissue obtained fro... | null | 0.768 | 131 | Surgery | Medicine | 2,002 |
12,125,984 | Concurrent modified PCV chemotherapy and radiotherapy in newly diagnosed grade IV astrocytoma. | Journal of neuro-oncology | J Neurooncol | 57 | 3 | 10.1023/a:1015797713149 | eng | 2,002 | 5 | null | null | null | null | [UNLABELLED] Adjuvant chemotherapy (CT) in the treatment of grade IV astrocytoma is at best modestly effective. The radiosensitizing effect of CT may confer an advantage to concurrent radiotherapy (RT) and CT. This study investigated concurrent procarbazine, lomustine, and vincristine (PCV) CT in newly diagnosed grade ... | null | 0.666 | 141 | Cancer Research; Neurology; Neurology; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience | 2,002 |
12,125,086 | Carpal tunnel syndrome among apprentice construction workers. | American journal of industrial medicine | Am J Ind Med | 42 | 2 | 10.1002/ajim.10093 | eng | 2,002 | 8 | null | null | null | null | [BACKGROUND] In terms of lost-work time and restricted workdays, surgery, and rehabilitation, one of the most costly occupational musculoskeletal disorders is carpal tunnel syndrome (CTS). The purpose of this study was to determine the prevalence of CTS among apprentice construction workers. [METHODS] This cross-sectio... | null | 0.985 | 120 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
12,124,826 | Initial decline in hemoglobin during neoadjuvant hormonal therapy predicts for early prostate specific antigen failure following radiation and hormonal therapy for patients with intermediate and high-risk prostate cancer. | Cancer | Cancer | 95 | 2 | 10.1002/cncr.10673 | eng | 2,002 | 7 | 15 | null | null | null | [BACKGROUND] Declines in serum hemoglobin (Hgb) levels occur from the use of androgen suppression therapy (AST) in the treatment of prostate cancer patients. We studied whether time to prostate specific antigen (PSA) failure following external beam radiation therapy (RT) and AST could be predicted by the rate of declin... | null | 1.595 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
12,124,667 | Effects of coping on psychological outcome when controlling for background variables: a study of traumatically spinal cord lesioned persons. | Spinal cord | Spinal Cord | 40 | 8 | 10.1038/sj.sc.3101299 | eng | 2,002 | 8 | null | null | null | null | [STUDY DESIGN] Cross-sectional. [OBJECTIVES] In a previous study we found spinal cord lesion (SCL)-related coping factors to be distinctly related to levels of SCL-related psychological outcome. However, we did not control for other potentially confounding variables. In this study we investigated effects of coping stra... | null | 0.618 | 131 | Medicine; Neurology; Neurology | Medicine; Neuroscience | 2,002 |
12,121,707 | Growth hormone increases circulating neutrophil activation and provokes lung microvascular injury in septic peritonitis rats. | The Journal of surgical research | J Surg Res | 105 | 2 | 10.1006/jsre.2002.6374 | eng | 2,002 | 6 | 15 | null | null | null | [BACKGROUND] Growth hormone (GH) has been shown to increase mortality in critical illness, illustrating the need for better understanding of GH treatment. The neutrophil is a key mediator in producing organ injury following shock and trauma and is regulated by GH. Therefore, the purpose of the present study was to exam... | null | 0.768 | 131 | Surgery | Medicine | 2,002 |
12,121,698 | Role of L-selectin in the development of ventilator-associated pneumonia in patients after major surgery. | The Journal of surgical research | J Surg Res | 105 | 2 | 10.1006/jsre.2002.6373 | eng | 2,002 | 6 | 15 | null | null | null | [BACKGROUND] The circulating level of soluble L-selectin (sL-selectin) has been reported to be low in adult respiratory distress syndrome and acute lung injury. This study explores the role of L-selectin in the development of ventilator-associated pneumonia (VAP) in patients undergoing major surgery. [PATIENTS AND METH... | null | 0.768 | 131 | Surgery | Medicine | 2,002 |
12,121,310 | Estrogen treatment protects GABA(B) inhibition in the dentate gyrus of female rats after kainic acid-induced status epilepticus. | Epilepsia | Epilepsia | 43 Suppl 5 | null | 10.1046/j.1528-1157.43.s.5.3.x | eng | 2,002 | null | null | null | null | null | [PURPOSE] We used the paired-pulse inhibition paradigm to determine whether the cell loss in the hilus of the dentate gyrus of female rats after kainic acid (KA)-induced status epilepticus (SE) is associated with functional changes in the dentate gyrus. Additionally, we determined whether the lost function could be pre... | null | 1.365 | 228 | Neurology; Neurology | Medicine; Neuroscience | 2,002 |
12,121,207 | Pain in somatoform disorders: is somatoform pain disorder a valid diagnosis? | Acta psychiatrica Scandinavica | Acta Psychiatr Scand | 106 | 2 | 10.1034/j.1600-0447.2002.02219.x | eng | 2,002 | 8 | null | null | null | null | [OBJECTIVE] Investigate the validity of DSM-IIIR somatoform pain disorder (SPD) by comparing subgroups of somatoform disorder patients on several measures of psychopathology. [METHOD] A total of 144 patients with unexplained physical symptoms were referred from non-psychiatric departments. Among these, 127 patients wit... | null | 1.68 | 174 | Psychiatry and Mental Health | Medicine | 2,002 |
12,121,196 | Can we determine a threshold level for allergenic foods by statistical analysis of published data in the literature? | Allergy | Allergy | 57 | 8 | 10.1034/j.1398-9995.2002.23797.x | eng | 2,002 | 8 | null | null | null | null | [BACKGROUND] The aim of this paper was to investigate whether a statistical model could be developed to estimate a "threshold" dose for foods eliciting allergic reactions in susceptible patients. The threshold dose is defined to be one that elicits allergic reactions in a given (small) proportion of susceptible patient... | null | 0.966 | 213 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,002 |
12,120,970 | Exploration of the acute scrotum: a retrospective analysis of 100 consecutive cases. | Irish journal of medical science | Ir J Med Sci | 170 | 3 | 10.1007/BF03173885 | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Acute scrotal pain is a common urological emergency. Urgent exploration is the standard means of management, as no investigation can confidently exclude torsion of testis from the differential diagnoses. In our department, all patients up to the age of 40 years, presenting with acute scrotal pain undergo e... | null | 0.161 | 46 | Medicine | Medicine | 2,001 |
12,120,855 | Parental expressed emotion in depressed adolescents: prediction of clinical course and relationship to comorbid disorders and social functioning. | Journal of child psychology and psychiatry, and allied disciplines | J Child Psychol Psychiatry | 43 | 5 | 10.1111/1469-7610.00048 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] High expressed emotion (EE) predicts worse clinical course for a number of disorders. High EE is more frequent in parents of disordered children than normal controls. It is uncertain whether EE and its components are disorder-specific, whether EE is more closely related to parent characteristics or child c... | null | 1.88 | 252 | Developmental and Educational Psychology; Pediatrics, Perinatology and Child Health; Psychiatry and Mental Health | Medicine; Psychology | 2,002 |
12,120,830 | The nature of newspaper coverage of homicide. | Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention | Inj Prev | 8 | 2 | 10.1136/ip.8.2.121 | eng | 2,002 | 6 | null | null | null | null | [OBJECTIVES] Previous research has shown that some homicides are more likely than others to receive newspaper coverage (for example, homicides by strangers). The present investigation examined whether, once the decision has been made to report on a homicide, the nature of the coverage (that is, how much visibility is g... | null | 0.457 | 99 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
12,120,203 | Autoimmune pancreatitis: possibilities of CT characterization. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] | Pancreatology | 1 | 3 | 10.1159/000055819 | eng | 2,001 | null | null | null | null | null | [BACKGROUND] Pancreatitis is defined as an inflammatory disease of the pancreas, leading to morphological and pathological changes. Recently, an autoimmune pathogenesis of this disease has been proposed. This type of pancreatitis should be differentiated from other pancreatic diseases, since appropriate therapy is effe... | null | null | 92 | Endocrinology; Endocrinology, Diabetes and Metabolism; Gastroenterology; Hepatology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,001 |
12,119,329 | Inhibition of vascular endothelial growth factor-mediated neointima progression with angiostatin or paclitaxel. | Journal of vascular and interventional radiology : JVIR | J Vasc Interv Radiol | 13 | 7 | 10.1016/s1051-0443(07)61847-8 | eng | 2,002 | 7 | null | null | null | null | [PURPOSE] Therapeutic angiogenesis represents a new paradigm for treatment of ischemic vascular syndromes. However, vascular endothelial growth factor (VEGF) enhances the rate and degree of plaque formation. This study evaluates the potential to block these effects nonspecifically with paclitaxel or specifically with a... | null | 1.037 | 150 | Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,002 |
12,118,909 | Correlation between diastolic impairment and lipid metabolism in mild-to-moderate hypertensive postmenopausal women. | American journal of hypertension | Am J Hypertens | 15 | 7 Pt 1 | 10.1016/s0895-7061(02)02934-5 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] Many cardiovascular risk factors are found in hypertensive patients. The aim of this study was to evaluate the correlation between cardiac abnormalities (ie, diastolic and left ventricular hypertrophy) with other cardiovascular risk factors in postmenopausal women with hypertension. [METHODS] A total of 20... | null | 0.969 | 156 | Internal Medicine | Medicine | 2,002 |
12,118,908 | Dopaminergic modulation of aldosterone secretions on changes of sodium intake in aldosterone-producing adenoma. | American journal of hypertension | Am J Hypertens | 15 | 7 Pt 1 | 10.1016/s0895-7061(02)02929-1 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] Impairment of renal dopamine excretion on high-salt diet (HS) may account for increased blood pressure (BP) in hypertensive subjects. Whether such impairment of dopaminergic activity exists in the adrenal gland is unknown. The purpose of this study was to differentiate degrees of dopaminergic inhibition of... | null | 0.969 | 156 | Internal Medicine | Medicine | 2,002 |
12,118,805 | Hydrodynamic function of the second-generation mitroflow pericardial bioprosthesis. | The Annals of thoracic surgery | Ann Thorac Surg | 74 | 1 | 10.1016/s0003-4975(02)03617-2 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] The hydrodynamic function of the smaller size Mitroflow Synergy stented pericardial bioprostheses has been studied in an in vitro fresh tissue aortic root model and compared with previous studies of free-sewn bioprostheses. [METHODS] Three valves of each of the sizes 19, 21, and 23 mm were sutured into fre... | null | 1.504 | 230 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,002 |
12,118,203 | TH1/TH2 balance in the subretinal fluid of patients with rhegmatogenous retinal detachment. | Medical science monitor : international medical journal of experimental and clinical research | Med Sci Monit | 8 | 7 | null | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] The pathogenesis of rhegmatogenous retinal detachments remains unclear, but some data suggest immune system involvement. Cytokines are substances secreted by cells in order to modulate the function of other cells. They exert primarily local effects. Because the TH1/TH2 balance is crucial in the immune resp... | null | 0.186 | 107 | Medicine | Medicine | 2,002 |
12,118,052 | Impact numbers: measures of risk factor impact on the whole population from case-control and cohort studies. | Journal of epidemiology and community health | J Epidemiol Community Health | 56 | 8 | 10.1136/jech.56.8.606 | eng | 2,002 | 8 | null | null | null | null | [OBJECTIVE] To describe new measures of risk from case-control and cohort studies, which are simple to understand and relate to numbers of the population at risk. [DESIGN] Theoretical development of new measures of risk. [SETTING] Review of literature and previously described measures. [MAIN RESULTS] The new measures a... | null | 1.259 | 199 | Epidemiology; Public Health, Environmental and Occupational Health | Medicine | 2,002 |
12,117,878 | Obesity and colorectal cancer risk in women. | Gut | Gut | 51 | 2 | 10.1136/gut.51.2.191 | eng | 2,002 | 8 | null | null | null | null | [BACKGROUND] Several large studies of obesity and colorectal cancer risk have found no association among women but a reasonably consistent positive association among men. In women, a positive association that is stronger among, or limited to, those who are premenopausal has been suggested by studies that stratified ana... | null | 2.104 | 364 | Gastroenterology | Medicine | 2,002 |
12,117,627 | Does early intervention increase latency to relapse in major depressive disorder? Re-evaluation with cognitive behavior therapy. | Journal of affective disorders | J Affect Disord | 70 | 2 | 10.1016/s0165-0327(01)00341-x | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] Major depressive disorder (MDD) has been studied in relation to its propensity for remission and likelihood of relapse. While the general clinical lore suggests that early intervention benefits treatment outcome, the empirical validation of this assumption is inconclusive. Specifically, no studies have bee... | null | 1.427 | 245 | Clinical Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,002 |
12,117,177 | Auckland paediatric liver transplant experience 1990-2000. | The New Zealand medical journal | N Z Med J | 115 | 1154 | null | eng | 2,002 | 5 | 24 | null | null | null | [AIMS] New Zealand is establishing its own Paediatric Liver Transplant Service. However there have been no readily available data on the experience of New Zealand paediatric transplant recipients to date. The aim of our study was to determine numbers and indications for transplant at present, current outcomes and to es... | null | 0.324 | 60 | Medicine | Medicine | 2,002 |
12,116,058 | Malignant vascular tumors in children and adolescents: a report from the Italian and German Soft Tissue Sarcoma Cooperative Group. | Medical and pediatric oncology | Med Pediatr Oncol | 39 | 2 | 10.1002/mpo.10078 | eng | 2,002 | 8 | null | null | null | null | [BACKGROUND] Malignant vascular tumors are extremely rare in childhood and few data on their clinical management are available. We report on a series of 18 children who had malignant vascular tumors, treated from 1980 to 2000 by the Italian and German Soft Tissue Sarcoma Cooperative Group. [PROCEDURE] Twelve patients h... | null | null | null | null | null | null |
12,115,778 | Prevalence of spina bifida and anencephaly during the transition to mandatory folic acid fortification in the United States. | Teratology | Teratology | 66 | 1 | 10.1002/tera.10060 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] In 1992, the United States Public Health Service recommended that all women of childbearing age consume 400 microg of folic acid daily. The Food and Drug Administration authorized the addition of synthetic folic acid to grain products in March 1996 with mandatory compliance by January 1998. The impact of t... | null | null | null | null | null | null |
12,115,301 | The effects of the current World Health Organization/International Society of Urologic Pathologists bladder neoplasm classification system on urine cytology results. | Cancer | Cancer | 96 | 3 | 10.1002/cncr.10621 | eng | 2,002 | 6 | 25 | null | null | null | [BACKGROUND] Historically, the diagnostic accuracy of urine cytology for the detection of urothelial carcinoma has been low, particularly for low-grade lesions. In 1998, the World Health Organization and International Society of Urologic Pathologists (WHO/ISUP) established a new classification system for urothelial neo... | null | 1.595 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,002 |
12,115,240 | Assessment of vascular function in systemic sclerosis: indications of the development of nitrate tolerance as a result of enhanced endothelial nitric oxide production. | Arthritis and rheumatism | Arthritis Rheum | 46 | 5 | 10.1002/art.10191 | eng | 2,002 | 5 | null | null | null | null | [OBJECTIVE] To investigate the relationship between endothelium-dependent and endothelium-independent functions and the stiffness of conduit arteries as well as levels of endothelial activation markers in patients with systemic sclerosis (SSc). [METHODS] Endothelium-dependent (i.e., flow-mediated) and endothelium-indep... | null | null | null | null | null | null |
12,115,196 | Takayasu arteritis: utility and limitations of magnetic resonance imaging in diagnosis and treatment. | Arthritis and rheumatism | Arthritis Rheum | 46 | 6 | 10.1002/art.10251 | eng | 2,002 | 6 | null | null | null | null | [OBJECTIVE] Previous studies have confirmed the poor correlation of symptoms, signs, and levels of acute-phase reactants with disease activity in approximately 50% of all patients with Takayasu arteritis (TA). Invasive angiographic studies demonstrate vessel lumen anatomy, but do not provide qualitative information abo... | null | null | null | null | null | null |
12,115,173 | Etanercept versus methotrexate in patients with early rheumatoid arthritis: two-year radiographic and clinical outcomes. | Arthritis and rheumatism | Arthritis Rheum | 46 | 6 | 10.1002/art.10308 | eng | 2,002 | 6 | null | null | null | null | [OBJECTIVE] To compare the clinical and radiographic outcomes in patients with rheumatoid arthritis (RA) who received monotherapy with either etanercept or methotrexate (MTX) for 2 years and to assess the safety of this therapy. [METHODS] In the Enbrel ERA (early rheumatoid arthritis) trial, 632 patients with early, ac... | null | null | null | null | null | null |
12,115,158 | A randomized controlled trial to evaluate the slow-acting symptom-modifying effects of colchicine in osteoarthritis of the knee: a preliminary report. | Arthritis and rheumatism | Arthritis Rheum | 47 | 3 | 10.1002/art.10455 | eng | 2,002 | 6 | 15 | null | null | null | [OBJECTIVE] To determine if colchicine added to nimesulide may have a beneficial effect on osteoarthritis (OA) of the knee. [METHODS] Colchicine 0.5 mg twice daily or placebo was added to nimesulide (a nonsteroidal antiinflammatory drug) in 36 patients with OA of the knee in a randomized, double-blind, placebo-controll... | null | null | null | null | null | null |
12,114,338 | A 6-month, placebo-controlled study comparing lung function and health status changes in COPD patients treated with tiotropium or salmeterol. | Chest | Chest | 122 | 1 | 10.1378/chest.122.1.47 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] Tiotropium, a once-daily anticholinergic, and salmeterol represent two inhaled, long-acting bronchodilators from different pharmacologic classes. A trial was designed to examine the efficacy and safety of both compounds with multiple outcome measures, including lung function, dyspnea, and health-related qu... | null | 1.171 | 337 | Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,002 |
12,113,884 | A pilot study of the effects of phytoestrogen supplementation on postmenopausal endometrium. | Journal of the Society for Gynecologic Investigation | J Soc Gynecol Investig | 9 | 4 | null | eng | 2,002 | null | null | null | null | null | [OBJECTIVE] This study was designed to assess endometrial histology in postmenopausal women not taking hormone replacement therapy, to evaluate side effects and efficacy of phytoestrogens in treating menopause-associated symptoms, and to determine whether 6 months of phytoestrogen supplementation altered endometrial hi... | null | null | null | null | null | null |
12,113,882 | Estrogen receptor alpha and progesterone receptor A and B concentration and localization in the lower uterine segment in term parturition. | Journal of the Society for Gynecologic Investigation | J Soc Gynecol Investig | 9 | 4 | null | eng | 2,002 | null | null | null | null | null | [OBJECTIVE] To determine the localization and concentrations of estrogen receptor alpha and progesterone receptors A and B in the lower uterine segment during term parturition. [METHODS] Biopsies were taken from 70 patients during nonelective cesarean delivery. The patients were at different stages of cervical dilatati... | null | null | null | null | null | null |
12,113,645 | Approaches toward repeated supratherapeutic doses of paracetamol in children: a survey of medical directors of poison centres in North America and Europe. | Drug safety | Drug Saf | 25 | 8 | 10.2165/00002018-200225080-00006 | eng | 2,002 | null | null | null | null | null | [BACKGROUND] During the last few years there has been an increase in the number of reports of liver failure associated with prolonged paracetamol (acetaminophen) administration in children for therapeutic reasons. [OBJECTIVE] To describe the approach taken by medical directors of poison centres regarding the treatment ... | null | 1.006 | 146 | Pharmacology; Pharmacology; Toxicology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,002 |
12,113,467 | Thoracolumbar proprioception in individuals with and without low back pain: intratester reliability, clinical applicability, and validity. | The Journal of orthopaedic and sports physical therapy | J Orthop Sports Phys Ther | 32 | 7 | 10.2519/jospt.2002.32.7.327 | eng | 2,002 | 7 | null | null | null | null | [STUDY DESIGN] Repeated measures design of active spinal position sense in individuals with and without low back pain (LBP). [OBJECTIVES] Reproducibility and validity evaluation of thoracolumbar proprioception measurement. [BACKGROUND] Proprioception studies in peripheral joints and the spine suggest that there may be ... | null | 0.676 | 152 | Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science | Health Professions; Medicine | 2,002 |
12,111,700 | Metallothionein isoform 3 expression inhibits cell growth and increases drug resistance of PC-3 prostate cancer cells. | The Prostate | Prostate | 52 | 2 | 10.1002/pros.10097 | eng | 2,002 | 7 | 1 | null | null | null | [BACKGROUND] The third isoform of metallothionein (MT-3) is overexpressed in prostate cancers and PIN lesions. The expression of MT-3 is highly variable but appears to correlate to Gleason score. The goal of the present study was to determine the effect of MT-3 overexpression on the growth of the PC-3 prostate cancer c... | null | 1.462 | 138 | Oncology; Urology | Medicine | 2,002 |
12,110,098 | Annual PSA tests are not necessary for men with a PSA level below 2 ng/mL: findings of the Imari prostate cancer screening program. | International journal of urology : official journal of the Japanese Urological Association | Int J Urol | 9 | 6 | 10.1046/j.1442-2042.2002.00474.x | eng | 2,002 | 6 | null | null | null | null | [BACKGROUND] Annual changes in prostate specific antigen (PSA) levels detected by the Imari prostate cancer screening program were evaluated to establish a more efficient and cost-saving screening system, especially for men with low PSA levels. [METHODS] Prostate specific antigen-based annual mass screenings for prosta... | null | 0.313 | 83 | Urology | Medicine | 2,002 |
12,110,071 | Screening for depression in patients in long-term care facilities: a randomized controlled trial of physician response. | Journal of the American Geriatrics Society | J Am Geriatr Soc | 50 | 6 | 10.1046/j.1532-5415.2002.50266.x | eng | 2,002 | 6 | null | null | null | null | [OBJECTIVES] To determine the effect of a screening protocol using the Geriatric Depression Scale (GDS) on the frequency of primary care physicians' decisions to prescribe drug therapy or refer long-term care patients with possible depression to mental health care. [DESIGN] Case-finding phase, followed by a randomized ... | null | 1.748 | 273 | Geriatrics and Gerontology | Medicine | 2,002 |
12,110,032 | Experimental diabetes induces functional and structural changes in the peritoneum. | Kidney international | Kidney Int | 62 | 2 | 10.1046/j.1523-1755.2002.00487.x | eng | 2,002 | 8 | null | null | null | null | [BACKGROUND] Peritoneal dialysis (PD) is an established renal replacement therapy in diabetic patients, but the influence of diabetes on the peritoneal membrane (PM) remains debated. We have used functional, biochemical and molecular studies in vivo and in vitro to substantiate the changes induced by diabetes and hyper... | null | null | null | null | null | null |
12,109,225 | NM23 expression as prognostic factor in colorectal carcinoma. | Il Giornale di chirurgia | G Chir | 23 | 3 | null | eng | 2,002 | 3 | null | null | null | null | [BACKGROUND] The current most important prognostic indicator in colorectal carcinoma is tumor stage at the moment of diagnosis. The role of NM23 gene as prognostic factor is controversial. The aim of this study was to investigate NM23 expression. [PATIENTS AND METHODS] The study population included 104 unselected patie... | null | null | null | null | null | null |
12,107,670 | Definitions and methods of cost assessment: an intensivist's guide. ESICM section on health research and outcome working group on cost effectiveness. | Intensive care medicine | Intensive Care Med | 28 | 6 | 10.1007/s00134-002-1279-5 | eng | 2,002 | 6 | null | 2,002 | 4 | 11 | [OBJECTIVE] To define the different types of costs incurred in the care of critically ill patients and to describe some of the most commonly used methods for measuring and allocating these costs. [DESIGN] Literature review. Definitions for opportunity, direct and indirect, fixed, variable, marginal, and total costs are... | null | 0.872 | 246 | Critical Care and Intensive Care Medicine | Medicine | 2,002 |
12,107,554 | Association of carmustine with a lipid emulsion: in vitro, in vivo and preliminary studies in cancer patients. | Cancer chemotherapy and pharmacology | Cancer Chemother Pharmacol | 49 | 6 | 10.1007/s00280-002-0437-3 | eng | 2,002 | 6 | null | 2,002 | 3 | 21 | [PURPOSE] We had previously shown in acute leukemia and in breast and ovary carcinoma patients that a cholesterol-rich emulsion (LDE) that binds to receptors for low-density lipoprotein (LDL) may concentrate in neoplastic tissues. In this study, the potential of LDE as a carrier for anticancer drugs was investigated. [... | null | 0.846 | 127 | Pharmacology; Pharmacology; Toxicology; Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,002 |
12,107,309 | Implant-related fractures of the femur following hip fracture surgery. | The Journal of bone and joint surgery. American volume | J Bone Joint Surg Am | 84 | 7 | 10.2106/00004623-200207000-00004 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND] Most hip fractures are treated surgically, with use of either internal fixation or prosthetic replacement of the femoral head. The presence of these implants increases the risk of a later femoral fracture in susceptible osteoporotic patients. The purpose of this study was to analyze the incidence of and ri... | null | null | null | null | null | null |
12,107,292 | Overtime work, insufficient sleep, and risk of non-fatal acute myocardial infarction in Japanese men. | Occupational and environmental medicine | Occup Environ Med | 59 | 7 | 10.1136/oem.59.7.447 | eng | 2,002 | 7 | null | null | null | null | [OBJECTIVES] To examine the relation between working hours and hours of sleep and the risk of acute myocardial infarction (AMI), with special reference to the joint effect of these two factors. [METHOD] Case-control study in Japan. Cases were 260 men aged 40-79 admitted to hospitals with AMI during 1996-8. Controls wer... | null | 1.209 | 167 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
12,105,858 | IIIc isoform of fibroblast growth factor receptor 1 is overexpressed in human pancreatic cancer and enhances tumorigenicity of hamster ductal cells. | Gastroenterology | Gastroenterology | 123 | 1 | 10.1053/gast.2002.34174 | eng | 2,002 | 7 | null | null | null | null | [BACKGROUND AND AIMS] Fibroblast growth factors (FGFs) are mitogenic polypeptides that signal via FGF receptors (FGFRs). Pancreatic ductal adenocarcinomas (PDACs) overexpress multiple FGFs, implying a potential for growth modulation. In this study we investigated the importance of the IIIc splice variant of FGFR-1 (FGF... | null | 3.536 | 482 | Gastroenterology | Medicine | 2,002 |
12,105,358 | Endovascular coil embolization of cerebral aneurysm remnants after incomplete surgical obliteration. | Stroke | Stroke | 33 | 7 | 10.1161/01.str.0000019600.39315.d0 | eng | 2,002 | 7 | null | null | null | null | [INTRODUCTION] The presence of an aneurysm remnant after incomplete or unsuccessful surgical clipping is associated with persistent risk of regrowth and rupture, and additional treatment is generally recommended. Attempts at surgical re-exploration are technically difficult and carry significant risk. Endovascular ther... | null | 2.816 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,002 |
12,102,671 | Levetiracetam does not alter the pharmacokinetics of an oral contraceptive in healthy women. | Epilepsia | Epilepsia | 43 | 7 | 10.1046/j.1528-1157.2002.57701.x | eng | 2,002 | 7 | null | null | null | null | [PURPOSE] This study was designed to evaluate whether levetiracetam, a novel antiepileptic drug (AED), influences the pharmacokinetics of steroid oral contraceptives. [METHODS] During a run-in phase, 18 healthy female patients received an oral contraceptive containing ethinyl estradiol, 0.03 mg, and levonorgestrel, 0.1... | null | 1.365 | 228 | Neurology; Neurology | Medicine; Neuroscience | 2,002 |
12,102,387 | Assessment of genetic and environmental influences on differential ratings of within-family experiences and relationships in twins. | Psychological medicine | Psychol Med | 32 | 4 | 10.1017/s0033291702005639 | eng | 2,002 | 5 | null | null | null | null | [BACKGROUND] Although there is evidence that genetic factors influence individual differences in environmental risk exposure, there are few findings on genetic effects on differential parenting. The present study sought to examine this issue. [METHODS] The sample comprised 1,117 pairs of like-sex male and female twins,... | null | 2.44 | 251 | Applied Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,002 |
12,102,380 | Characterizing the effects of sertraline in post-traumatic stress disorder. | Psychological medicine | Psychol Med | 32 | 4 | 10.1017/s0033291702005469 | eng | 2,002 | 5 | null | null | null | null | [BACKGROUND] Sertraline has a proved efficacy in post-traumatic stress disorder (PTSD), but it is unknown which symptoms respond or in what sequence this occurs. Such information might be useful clinically and heuristically. [METHOD] The study examined the effects of sertraline on the individual symptoms of PTSD. It al... | null | 2.44 | 251 | Applied Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,002 |
12,102,131 | Improved confocal characterization of targets in nuclei of cytogenetic preparations. | Analytical and quantitative cytology and histology | Anal Quant Cytol Histol | 24 | 3 | null | eng | 2,002 | 6 | null | null | null | null | [OBJECTIVE] To show that cellular preparations requiring depth analysis of different domains stained by molecular cytogenetic methods (fluorescence in situ hybridization and primed in situ) can be improved by regularized factor analysis of medical image sequences (FAMIS) to isolate fluorescent probes by means of intens... | null | null | null | null | null | null |
12,101,538 | Emergency radiology in Canada: a national survey. | Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes | Can Assoc Radiol J | 53 | 3 | null | eng | 2,002 | 6 | null | null | null | null | [OBJECTIVE] To document the existing radiology services available to emergency physicians in hospitals across Canada and to preview future trends and needs. [METHODS] Questionnaires (n = 130) regarding the type, availability and satisfaction with radiology services were distributed to radiologists and emergency physici... | null | null | null | null | null | null |
12,101,192 | Total research productivity in a pathology discipline. | Journal of clinical pathology | J Clin Pathol | 55 | 7 | 10.1136/jcp.55.7.495 | eng | 2,002 | 7 | null | null | null | null | [AIMS] To investigate the research productivity of all staff in chemical pathology. [METHODS] Chemical pathologists or biochemical scientists were identified from publicly available sources. All journals, their impact factors (IFs), and individual publications over the period of 1995 to 1999 were identified from electr... | null | 0.759 | 158 | Medicine; Pathology and Forensic Medicine | Medicine | 2,002 |
12,101,156 | Recognition of death and termination of cardiac resuscitation attempts by UK ambulance personnel. | Emergency medicine journal : EMJ | Emerg Med J | 19 | 4 | 10.1136/emj.19.4.345 | eng | 2,002 | 7 | null | null | null | null | [OBJECTIVES] To identify whether the practice of the UK ambulance trusts comply with national recommendations with respect to when ambulance personnel are allowed to recognise death and/or terminate resuscitation attempts in the adult, normothermic, non-traumatic cardiac arrest. [METHODS] Questionnaire study of 39 ambu... | null | 0.286 | 100 | Critical Care and Intensive Care Medicine; Emergency Medicine; Medicine | Medicine | 2,002 |
12,100,923 | Selective bladder preservation by combined modality protocol treatment: long-term outcomes of 190 patients with invasive bladder cancer. | Urology | Urology | 60 | 1 | 10.1016/s0090-4295(02)01650-3 | eng | 2,002 | 7 | null | null | null | null | [OBJECTIVES] To evaluate the outcomes of patients with muscle-invasive Stage T2-4a bladder carcinoma managed by transurethral surgery and concurrent chemoradiation. [METHODS] A total of 190 patients were treated on institutional prospective protocols using concurrent cisplatin-containing chemotherapy and radiotherapy a... | null | 1.174 | 197 | Urology | Medicine | 2,002 |
12,100,689 | Association of psoriasis vulgaris with HLA class I and class II antigens in the Turkish population, according to the age at onset. | International journal of dermatology | Int J Dermatol | 41 | 6 | null | eng | 2,002 | 6 | null | null | null | null | [BACKGROUND] Association of psoriasis vulgaris with HLA antigens reference to age at onset has been reported in different racial or ethnic populations. [OBJECTIVE] Our purpose was to determine the distribution of HLA markers in the Turkish population according to the age at onset of the psoriasis vulgaris. [METHODS] HL... | null | 0.474 | 111 | Dermatology | Medicine | 2,002 |
12,100,627 | Study of HHV-8 DNA sequences in archival biopsies from lesional skin of Kaposi's sarcoma, various mesenchymal tumors and related reactive conditions. | Journal of cutaneous pathology | J Cutan Pathol | 29 | 5 | 10.1034/j.1600-0560.2002.290503.x | eng | 2,002 | 5 | null | null | null | null | [BACKGROUND] HHV-8 has been identified as the causative agent of Kaposi's sarcoma (KS) and some lymphoproliferative disorders. In addition, there are anecdotal reports on the presence of HHV-8 in other tumors, especially cutaneous epithelial and mesenchymal neoplasms. The aim of the study was to ascertain the value of ... | null | 0.708 | 89 | Dermatology; Histology; Pathology and Forensic Medicine | Medicine | 2,002 |
12,100,349 | Subjective quality of life: validity issues with depressed patients. | Acta psychiatrica Scandinavica | Acta Psychiatr Scand | 106 | 1 | 10.1034/j.1600-0447.2002.02204.x | eng | 2,002 | 7 | null | null | null | null | [OBJECTIVE] To compare depressed patients at different stages of illness and healthy controls on objective and subjective quality of life (QOL) measures and to determine the responsiveness of subjective QOL ratings to change in depression. [METHOD] A cohort of 56 depressed in-patients was followed-up for up to 16 month... | null | 1.68 | 174 | Psychiatry and Mental Health | Medicine | 2,002 |
12,100,322 | Differential diagnosis between thymoma and non-thymoma by dynamic MR imaging. | Acta radiologica (Stockholm, Sweden : 1987) | Acta Radiol | 43 | 3 | 10.1080/j.1600-0455.2002.430306.x | eng | 2,002 | 5 | null | null | null | null | [PURPOSE] To evaluate the usefulness of dynamic MR imaging for differential diagnosis of anterior mediastinal tumors. [MATERIAL AND METHODS] Fifty-nine patients with anterior mediastinal tumors were examined. According to histological diagnosis confirmed by surgery or biopsy, 31 had thymomas and 28 had non-thymoma lesi... | null | 0.548 | 82 | Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging | Health Professions; Medicine | 2,002 |
12,100,321 | High-resolution carotid artery MRA. Comparison with fast dynamic acquistion and duplex ultrasound scanning. | Acta radiologica (Stockholm, Sweden : 1987) | Acta Radiol | 43 | 3 | 10.1080/j.1600-0455.2002.430305.x | eng | 2,002 | 5 | null | null | null | null | [PURPOSE] To determine whether the diagnostic accuracy of contrast-enhanced MR angiography (CE-MRA) of the carotid arteries is improved by using a slow-injection, high-resolution technique. [MATERIAL AND METHODS] In 22 patients suspected to have internal carotid artery (ICA) stenosis at duplex ultrasound scanning (DUS)... | null | 0.548 | 82 | Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging | Health Professions; Medicine | 2,002 |
12,100,223 | The effect of rizatriptan, ergotamine, and their combination on human peripheral arteries: a double-blind, placebo-controlled, crossover study in normal subjects. | British journal of clinical pharmacology | Br J Clin Pharmacol | 54 | 1 | 10.1046/j.1365-2125.2002.01403.x | eng | 2,002 | 7 | null | null | null | null | [AIMS] To compare the peripheral vasoconstrictor effects of ergotamine, rizatriptan, and their combination, in normal subjects. [METHODS] This was a double-blind, four-way, crossover study. Sixteen young male volunteers, selected as responders to the vasoconstrictor effect of 0.5 mg ergotamine i.v., were administered 1... | null | 0.808 | 176 | Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,002 |
12,100,075 | Lipid profiles in untreated severe congenital isolated growth hormone deficiency through the lifespan. | Clinical endocrinology | Clin Endocrinol (Oxf) | 57 | 1 | 10.1046/j.1365-2265.2002.01568.x | eng | 2,002 | 7 | null | null | null | null | [OBJECTIVE] Growth hormone deficiency (GHD) is associated with adverse changes in lipid profile. However, changes in lipids through life in a homogeneous group of GHD subjects have not been defined. [PATIENTS AND MEASUREMENTS] We examined lipid levels in a group of untreated severely GHD patients with a mutation in the... | null | 1.061 | 169 | Endocrinology, Diabetes and Metabolism | Medicine | 2,002 |
12,099,658 | The novel technique of delivering targeted intraoperative radiotherapy (Targit) for early breast cancer. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology | Eur J Surg Oncol | 28 | 4 | 10.1053/ejso.2002.1275 | eng | 2,002 | 6 | null | null | null | null | [AIM] We believe that conservative treatment of early breast cancer may not require radiotherapy that encompasses the whole breast in all patients. We have developed a novel therapeutic approach that allows targeted intraoperative radiotherapy (Targit) to be safely and accurately delivered in a standard operating theat... | null | 0.549 | 123 | Medicine; Oncology; Surgery | Medicine | 2,002 |
12,098,144 | Effectiveness of a lateral-wedge insole on knee varus torque in patients with knee osteoarthritis. | Archives of physical medicine and rehabilitation | Arch Phys Med Rehabil | 83 | 7 | 10.1053/apmr.2002.33225 | eng | 2,002 | 7 | null | null | null | null | [OBJECTIVES] To test whether a lateral-wedged insole, inclined at 5 degrees or 10 degrees, significantly reduces knee varus torque during walking in patients with knee osteoarthritis compared with both using no insole and with wearing nonwedged control insoles of the same material and average thickness. [DESIGN] Patien... | null | 1.038 | 225 | Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science | Health Professions; Medicine | 2,002 |
12,096,938 | Learning curve for endovascular abdominal aortic aneurysm repair: evaluation of a 277-patient single-center experience. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists | J Endovasc Ther | 9 | 3 | 10.1177/152660280200900302 | eng | 2,002 | 6 | null | null | null | null | [PURPOSE] To determine the minimum number of stent-graft deployments that an interventional team with endovascular skills must do to be considered well trained in endovascular abdominal aortic aneurysm (AAA) exclusion. [METHODS] The records of 277 consecutive patients (236 men; median age 73 years, range 49-91) undergo... | null | 1.466 | 112 | Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,002 |
12,096,298 | Addressing the support needs of women at high risk for breast cancer: evidence-based care by advanced practice nurses. | Oncology nursing forum | Oncol Nurs Forum | 29 | 6 | 10.1188/02.ONF.E77-E84 | eng | 2,002 | 7 | null | null | null | null | [PURPOSE/OBJECTIVES] To identify support needs of women at high risk for breast cancer and enhance an evidence-based service. [DESIGN] Descriptive study. [SETTING] A comprehensive, breast-health service for high-risk women. [SAMPLE] 97 high-risk women with a 1.66% or greater five-year risk of breast cancer, atypical hy... | null | null | null | null | null | null |
12,207,111 | In vitro effect of fluticasone propionate on interleukin 8 production by monocytes obtained from patients affected by moderate-severe allergic asthma. | Pharmacology | Pharmacology | 66 | 2 | 10.1159/000065626 | eng | 2,002 | 10 | null | null | null | null | [BACKGROUND] Interleukin-8 (IL-8), a potent chemotactic and activating factor for neutrophils and eosinophils, may be a crucial factor in severe asthma. The aim of this study was to evaluate the effect of fluticasone propionate (FP), a corticosteroid with potent anti-inflammatory activity, on the in vitro release of IL... | null | 0.452 | 70 | Medicine; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,002 |
12,207,129 | Intravitreal penetration of cefepime after systemic administration to humans. | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde | Ophthalmologica | 216 | 4 | 10.1159/000063838 | eng | 2,002 | null | null | null | null | null | [PURPOSE] To investigate the penetration of cefepime (a fourth-generation cephalosporin) into the vitreous after single-dose intravenous administration to human subjects. [METHODS] Thirty phakic patients about to undergo vitreous surgery received 1 g (group 1, 15 patients) or 2 g cefepime (group 2, 15 patients) in a si... | null | null | null | null | null | null |
12,206,939 | Does a pelvic belt influence sacroiliac joint laxity? | Clinical biomechanics (Bristol, Avon) | Clin Biomech (Bristol) | 17 | 7 | 10.1016/s0268-0033(02)00045-1 | eng | 2,002 | 8 | null | null | null | null | [OBJECTIVE] To evaluate the influence of different positions and tensions of a pelvic belt on sacroiliac joint laxity in healthy young women. [BACKGROUND] Clinical experience has shown that positive effects can be obtained with different positions and tensions of a pelvic belt. A functional approach to the treatment of... | null | null | null | null | null | null |
12,206,402 | Bacterial and yeast flora of root surface caries in elderly, ethnic Chinese. | Oral diseases | Oral Dis | 8 | 4 | 10.1034/j.1601-0825.2002.01796.x | eng | 2,002 | 7 | null | null | null | null | [OBJECTIVES] Root caries is emerging as a significant problem in the middle aged and elderly. As little data is available on the microbiology of root caries in Chinese cohorts, we evaluated 30 such lesions in elderly, institutionalized, ethnic Chinese. [METHODS] Samples of carious dentine were aseptically taken from ro... | null | 0.34 | 109 | Dentistry; Otorhinolaryngology | Dentistry; Medicine | 2,002 |
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