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12,435,988 | Physiology of chronic spinal pain syndromes: from animal models to biomechanics. | Spine | Spine (Phila Pa 1976) | 27 | 22 | 10.1097/00007632-200211150-00026 | eng | 2,002 | 11 | 15 | null | null | null | [STUDY DESIGN] The literature and current research related to spinal pain mechanisms were reviewed, as well as animal models related to its study. [OBJECTIVES] To provide a pragmatic discussion of spinal pain that both reviews relevant research and coherently synthesizes the existing body of literature related to pain,... | null | 1.336 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,002 |
12,435,940 | 23-Hour observation solely for identification of missed injuries after trauma: is it justified? | The Journal of trauma | J Trauma | 53 | 5 | 10.1097/00005373-200211000-00014 | eng | 2,002 | 11 | null | null | null | null | [BACKGROUND] The use of an observation period to identify missed injuries in trauma patients has gained favor in recent years. This study was undertaken in a population of patients with minimal or no identified injuries to determine the following: whether a period of in-patient observation identifies missed injuries; d... | null | null | null | null | null | null |
12,435,832 | The Health Intervention Project: HIV risk reduction among African American women drug users. | Public health reports (Washington, D.C. : 1974) | Public Health Rep | 117 Suppl 1 | Suppl 1 | null | eng | 2,002 | null | null | null | null | null | [OBJECTIVE] This article describes the Health Intervention Project, an intervention for African American women in Atlanta, Georgia, who are crack cocaine users. [METHODS] A formative phase involved ethnographic mapping of the physical and social infrastructure of the study communities and in-depth interviews with women... | null | 0.56 | 111 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
12,435,646 | Clinical assessment of three common tests for superior labral anterior-posterior lesions. | The American journal of sports medicine | Am J Sports Med | 30 | 6 | 10.1177/03635465020300061001 | eng | 2,002 | null | null | null | null | null | [BACKGROUND] Three tests (active compression, anterior slide, and compression rotation) are commonly used to diagnose superior labral anterior-posterior lesions. [HYPOTHESIS] We hypothesized that the accuracy, sensitivity, and specificity for these tests was less than that previously reported and that a click in the sh... | null | 2.183 | 277 | Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science | Health Professions; Medicine | 2,002 |
12,435,644 | The effect of initial graft tension in anterior cruciate ligament reconstruction on the mechanical behaviors of the femur-graft-tibia complex during cyclic loading. | The American journal of sports medicine | Am J Sports Med | 30 | 6 | 10.1177/03635465020300060801 | eng | 2,002 | null | null | null | null | null | [BACKGROUND] Initial graft tension influences clinical results of anterior cruciate ligament reconstruction. [HYPOTHESIS] Under repetitive loading conditions, the effect of initial graft tension on the biomechanical behavior of the femur-graft-tibia complex may depend on the graft and the fixation. [STUDY DESIGN] Ex vi... | null | 2.183 | 277 | Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science | Health Professions; Medicine | 2,002 |
12,434,886 | Whole-body mineral measurements in Swedish adolescents at 17 years compared to 15 years of age. | Acta paediatrica (Oslo, Norway : 1992) | Acta Paediatr | 91 | 10 | 10.1080/080352502760311502 | eng | 2,002 | null | null | null | null | null | [AIM] To provide reference data for bone mineral variables in 15- and 17-y-old adolescents and to analyse the relationships between these variables and measures of bone and body size, gender, puberty, growth, various lifestyle and environmental factors and socioeconomic background. [METHODS] In the same 321 randomly se... | null | null | null | null | null | null |
12,434,608 | The effect of anesthetic techniques on hemostatic function in arthroscopic surgery: evaluation by thromboelastography. | Acta anaesthesiologica Sinica | Acta Anaesthesiol Sin | 40 | 3 | null | eng | 2,002 | 9 | null | null | null | null | [BACKGROUND] Anesthetic techniques are known to affect blood hemostasis, which may be responsible for the pathogenesis of postoperative venous thromboembolism. The purpose of this study was to evaluate the effect of general and spinal anesthesias on blood hemostasis using thromboelastography. [METHODS] Forty patients u... | null | null | null | null | null | null |
12,432,591 | Success rate of complete extraction of common bile duct stones at first endoscopy attempt. | Revista espanola de enfermedades digestivas | Rev Esp Enferm Dig | 94 | 6 | null | eng | 2,002 | 6 | null | null | null | null | [BACKGROUND AND AIM] ERCP with biliary sphincterotomy is the usual method to extract common bile duct stones. However, after sphincterotomy and by means of balloons and Dormia baskets not all stones may be extracted during the first endoscopy session. We present our experience regarding success rate after first ERCP. [... | null | null | null | null | null | null |
12,432,158 | Dissemination of the AHCPR clinical practice guideline in community health centres. | Tobacco control | Tob Control | 11 | 4 | 10.1136/tc.11.4.329 | eng | 2,002 | 12 | null | null | null | null | [OBJECTIVE] To evaluate dissemination of the Agency for Health Care Policy and Research (AHCPR) Smoking cessation clinical practice guideline in community health centres. [DESIGN] Pre- and post-trial. [SETTING] Fourteen community health centres in Rhode Island. [SUBJECTS] Provider performance was assessed with 1798 and... | null | 1.17 | 147 | Health; Public Health, Environmental and Occupational Health | Medicine; Social Sciences | 2,002 |
12,432,135 | Effect of race and/or ethnicity in use of antiretrovirals and prophylaxis for opportunistic infection: a review of the literature. | Public health reports (Washington, D.C. : 1974) | Public Health Rep | 117 | 3 | 10.1093/phr/117.3.233 | eng | 2,002 | null | null | null | null | null | [OBJECTIVE] The authors performed a systematic and critical review of published studies investigating potential associations between race and/or ethnicity and use of HIV-related medications, including antiretroviral medications and medications used for prophylaxis of opportunistic infections. [METHODS] The authors cond... | null | 0.56 | 111 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
12,431,356 | Primary and booster vaccination with DTPw-HB/Hib pentavalent vaccine in Costa Rican children who had received a birth dose of hepatitis B vaccine. | Revista panamericana de salud publica = Pan American journal of public health | Rev Panam Salud Publica | 12 | 4 | 10.1590/s1020-49892002001000005 | eng | 2,002 | 10 | null | null | null | null | [OBJECTIVE] The DTPw-HB/Hib pentavalent combination vaccine has been developed following recommendations of the World Health Organization for the introduction of hepatitis B (HB) and Haemophilus influenzae type b (Hib) vaccines into routine childhood vaccination programs. The objectives of this study were to: 1) analyz... | null | 0.235 | 69 | Public Health, Environmental and Occupational Health | Medicine | 2,002 |
12,430,575 | Regular alcohol intake and fibrinolysis. | The Netherlands journal of medicine | Neth J Med | 60 | 7 | null | eng | 2,002 | 8 | null | null | null | null | [BACKGROUND] Light to moderate alcohol consumption is associated with a reduced risk of coronary heart disease. Stimulation of fibrinolysis has been suggested as one of the mechanisms involved. The present study analyses the effect of regular alcohol consumption on various parameters of fibrinolysis. The question wheth... | null | null | null | null | null | null |
12,429,304 | Renovascular complications of laparoscopic donor nephrectomy. | Urology | Urology | 60 | 5 | 10.1016/s0090-4295(02)01916-7 | eng | 2,002 | 11 | null | null | null | null | [OBJECTIVES] To review the operative renovascular injuries related to our laparoscopic donor nephrectomy experience, since management of intraoperative renovascular complications during laparoscopic nephrectomy can present a serious challenge. [METHODS] During a 6-year period, 353 patients underwent laparoscopic donor ... | null | 1.174 | 197 | Urology | Medicine | 2,002 |
12,429,063 | The society of genes: networks of functional links between genes from comparative genomics. | Genome biology | Genome Biol | 3 | 11 | 10.1186/gb-2002-3-11-research0064 | eng | 2,002 | 10 | 25 | 2,002 | 10 | 25 | [BACKGROUND] Comparative genomics provides at least three methods beyond traditional sequence similarity for identifying functional links between genes: the examination of common phylogenetic distributions, the analysis of conserved proximity along the chromosomes of multiple genomes, and observations of fusions of gen... | null | null | null | null | null | null |
12,428,697 | Situation analysis of atypical squamous cells of undetermined significance smears in Songklanagarind Hospital. | The journal of obstetrics and gynaecology research | J Obstet Gynaecol Res | 28 | 5 | 10.1046/j.1341-8076.2002.00054.x | eng | 2,002 | 10 | null | null | null | null | [OBJECTIVE] To review the incidence, management, follow-up rate and colposcopic diagnosis of atypical squamous cells of undetermined significance (ASCUS) detected on cervical smears in Songklanagarind Hospital, Thailand. [METHODS] A retrospective study of ASCUS smears taken during January 2000 to March 2001 at Songklan... | null | 0.309 | 68 | Medicine; Obstetrics and Gynecology | Medicine | 2,002 |
12,428,174 | Biochemical deficiency of pyridoxine does not affect interleukin-2 production of lymphocytes from patients with Sjögren's syndrome. | European journal of clinical nutrition | Eur J Clin Nutr | 56 | 11 | 10.1038/sj.ejcn.1601450 | eng | 2,002 | 11 | null | null | null | null | [BACKGROUND] There is evidence that pyridoxine deficiency may alter the immune response. It is not known whether a deficiency of this vitamin is evident in subjects with primary Sjögren's syndrome (SS). [OBJECTIVE] We studied whether subjects with primary SS showed a biochemical deficiency of pyridoxine, and if it is a... | null | 0.945 | 187 | Medicine; Nutrition and Dietetics | Medicine; Nursing | 2,002 |
12,427,639 | Time-of-flight MR angiography of carotid artery stenosis: does a flow void represent severe stenosis? | AJNR. American journal of neuroradiology | AJNR Am J Neuroradiol | 23 | 10 | null | eng | 2,002 | null | null | null | null | null | [BACKGROUND AND PURPOSE] Time-of-flight (TOF) magnetic resonance angiography (MRA) is commonly used to visualize the carotid arteries; however, flow void artifacts can appear. Our purpose was to determine the frequency and diagnostic meaning of flow voids by using real patient data, as part of a larger study of MRA com... | null | null | null | null | null | null |
12,427,612 | CT and MR imaging of solitary extramedullary plasmacytoma of the nasal tract. | AJNR. American journal of neuroradiology | AJNR Am J Neuroradiol | 23 | 10 | null | eng | 2,002 | null | null | null | null | null | [BACKGROUND AND PURPOSE] Solitary extramedullary plasmacytoma (SEP) is rare. The purpose of this study was to determine the CT and MR imaging features of SEP of the nasal tract. [METHODS] We retrospectively reviewed three CT and two MR images of three histologically proved cases in two men and one woman aged 43-66 year... | null | null | null | null | null | null |
12,427,148 | Cost savings of home nocturnal versus conventional in-center hemodialysis. | Kidney international | Kidney Int | 62 | 6 | 10.1046/j.1523-1755.2002.00678.x | eng | 2,002 | 12 | null | null | null | null | [BACKGROUND] Home nocturnal hemodialysis (HNHD) can improve clinical and biochemical factors in people with renal failure, but its cost-effectiveness relative to conventional in-center hemodialysis (IHD) is uncertain. We hypothesized that HNHD would provide more dialysis treatments at a lower total cost than IHD. [METH... | null | null | null | null | null | null |
12,426,925 | Prosthetic heart valve thrombosis: an overview. | WMJ : official publication of the State Medical Society of Wisconsin | WMJ | 101 | 7 | null | eng | 2,002 | null | null | null | null | null | [BACKGROUND] Valvular heart disease represents a significant burden to patients with cardiovascular diseases. Surgical treatment of diseased heart valves represents a significant advancement for these patients. However, there are specific complications related to prosthetic valves, including valve thrombosis. [METHODS]... | null | null | null | null | null | null |
12,426,670 | Radiotherapy confined to the tumor bed following breast conserving surgery current status, controversies, and future projects. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] | Strahlenther Onkol | 178 | 11 | 10.1007/s00066-002-0966-z | eng | 2,002 | 11 | null | null | null | null | [BACKGROUND] The standard technique of radiotherapy (RT) after breast conserving surgery (BCS) is to treat the entire breast up to a total dose of 45-50 Gy with or without tumor bed boost. The majority of local recurrences occur in close proximity to the tumor bed. Thus, the necessity of whole breast radiotherapy has b... | null | 0.54 | 81 | Oncology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,002 |
12,426,544 | Arthroscopic biceps tenodesis: a new technique using bioabsorbable interference screw fixation. | Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association | Arthroscopy | 18 | 9 | 10.1053/jars.2002.36488 | eng | 2,002 | null | null | null | null | null | [PURPOSE] To report a new technique of arthroscopic biceps tenodesis using bioabsorbable interference screw fixation and the early results. [TYPE OF STUDY] Prospective, nonrandomized study. [TECHNIQUE] The principle of arthroscopic biceps tenodesis is simple: after biceps tenotomy, the tendon is exteriorized and double... | null | null | null | null | null | null |
12,426,522 | Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene. | Clinical pharmacology and therapeutics | Clin Pharmacol Ther | 72 | 5 | 10.1067/mcp.2002.129196 | eng | 2,002 | 11 | null | null | null | null | [OBJECTIVE] We investigated the effect of polymorphisms in the P-glycoprotein (P-gp) MDR1 gene on steady-state pharmacokinetics of digoxin in Caucasians. According to earlier data, homozygous TT of the exon 26 complementary deoxyribonucleic acid (cDNA) 3435C>T polymorphism was associated with low P-gp expression in the... | null | null | null | null | null | null |
12,426,287 | Worldwide racial and ethnic distribution of alpha1-antitrypsin deficiency: summary of an analysis of published genetic epidemiologic surveys. | Chest | Chest | 122 | 5 | 10.1378/chest.122.5.1818 | eng | 2,002 | 11 | null | null | null | null | [STUDY OBJECTIVES] Alpha1-antitrypsin (AAT) deficiency is a genetic disease that is widely known in Europe as a disease of white individuals, who, along with their descendants in other parts of the world, are at the highest risk for liver and/or lung disease. There is a limited database of individuals affected by this ... | null | 1.171 | 337 | Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,002 |
12,426,272 | Tissue hypoxia in sleep apnea syndrome assessed by uric acid and adenosine. | Chest | Chest | 122 | 5 | 10.1378/chest.122.5.1686 | eng | 2,002 | 11 | null | null | null | null | [STUDY OBJECTIVE] Although the overnight increase in urinary uric acid/creatinine ratio (DeltaUA/Cr) is considered by some to be a marker of tissue hypoxia in patients with obstructive sleep apnea-hypopnea syndrome (OSAS), this index is not universally accepted. The purpose of this study was to confirm the validity of ... | null | 1.171 | 337 | Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,002 |
12,426,262 | Structural changes of the airway wall impair respiratory function, even in mild asthma. | Chest | Chest | 122 | 5 | 10.1378/chest.122.5.1622 | eng | 2,002 | 11 | null | null | null | null | [STUDY OBJECTIVES] To clarify whether structural changes of the airway wall impair respiratory function in patients with mild asthma, and to determine whether mild asthma should be treated with inhaled steroids. [SETTING] Showa University Hospital in Tokyo. [PATIENTS] Thirteen healthy nonatopic volunteers (control subj... | null | 1.171 | 337 | Cardiology and Cardiovascular Medicine; Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,002 |
12,425,406 | Effects of an augmented postoperative fluid protocol on wound healing in cardiac surgery patients. | American journal of critical care : an official publication, American Association of Critical-Care Nurses | Am J Crit Care | 11 | 6 | null | eng | 2,002 | 11 | null | null | null | null | [BACKGROUND] Cardiac surgery patients are vulnerable to hypoperfusion postoperatively and often have subcutaneous tissue oxygen tension less than 50 mm Hg. Hypovolemia most likely contributes to this hypoperfusion and may lead to impaired wound healing. [OBJECTIVES] To determine if a modified postoperative fluid replac... | null | 0.515 | 95 | Critical Care Nursing; Medicine | Medicine; Nursing | 2,002 |
12,425,403 | An educational project to improve knowledge related to pulse oximetry. | American journal of critical care : an official publication, American Association of Critical-Care Nurses | Am J Crit Care | 11 | 6 | null | eng | 2,002 | 11 | null | null | null | null | [BACKGROUND] Pulse oximetry is a frequently used, noninvasive monitoring tool for assessing arterial blood oxygenation. Physicians, registered nurses, and respiratory therapists are responsible for the accurate interpretation of pulse oximetry data as part of the evaluation and management of acutely and critically ill ... | null | 0.515 | 95 | Critical Care Nursing; Medicine | Medicine; Nursing | 2,002 |
12,423,855 | Differential blood flow in uterine, ophthalmic, and brachial arteries of preeclamptic women. | Obstetrics and gynecology | Obstet Gynecol | 100 | 5 Pt 1 | 10.1016/s0029-7844(02)02244-5 | eng | 2,002 | 11 | null | null | null | null | [OBJECTIVE] To develop a method that employs noninvasive, pulsed Doppler ultrasonography combined with measurement of flow-mediated vasodilation to evaluate characteristic endothelial dysfunction in various degrees of preeclampsia. [METHODS] Uterine, ophthalmic, and brachial arterial blood flow of 99 pregnant women (co... | null | 1.319 | 268 | Obstetrics and Gynecology | Medicine | 2,002 |
12,423,291 | Assessment of periodontal conditions and systemic disease in older subjects. I. Focus on osteoporosis. | Journal of clinical periodontology | J Clin Periodontol | 29 | 9 | 10.1034/j.1600-051x.2002.290902.x | eng | 2,002 | 9 | null | null | null | null | [BACKGROUND] Osteoporosis (OPOR) is a common chronic disease, especially in older women. Patients are often unaware of the condition until they experience bone fractures. Studies have suggested that OPOR and periodontitis are associated diseases and exaggerated by cytokine activity. Panoramic radiography (PMX) allows s... | null | 0.974 | 187 | Periodontics | Dentistry | 2,002 |
12,422,334 | Clinical and electrophysiologic correlates of quantitative sensory testing in patients with incomplete spinal cord injury. | Archives of physical medicine and rehabilitation | Arch Phys Med Rehabil | 83 | 11 | 10.1053/apmr.2002.35101 | eng | 2,002 | 11 | null | null | null | null | [OBJECTIVE] To determine the degree of association among indices of preserved sensation derived from quantitative sensory testing (QST), somatosensory evoked potentials (SEPs), and the clinical characteristics of patients with spinal cord injury (SCI). [DESIGN] A controlled correlational study of diverse measures of pr... | null | 1.038 | 225 | Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science | Health Professions; Medicine | 2,002 |
12,422,250 | Naltrexone in the treatment of alcohol dependence: a Canadian trial. | The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique | Can J Clin Pharmacol | 9 | 3 | null | eng | 2,002 | null | null | null | null | null | [OBJECTIVES] Alcohol dependence is a prevalent psychiatric disorder affecting approximately 12% of the adult population at some point in their lifetime. Psychosocial treatments are associated with only modest success rates. The first Canadian clinical trial with naltrexone, an opiate antagonist, was conducted to evalua... | null | null | null | null | null | null |
12,422,159 | Effectiveness of percutaneous device occlusion for atrial septal defect in adult patients with pulmonary hypertension. | American heart journal | Am Heart J | 144 | 5 | 10.1067/mhj.2002.126121 | eng | 2,002 | 11 | null | null | null | null | [BACKGROUND] Adult patients with atrial septal defect (ASD) and pulmonary hypertension have a more advanced degree of disease, frequently having functional class deterioration and atrial arrhythmias when they are aged >40 years. Surgery at this age prolongs life expectancy and limits functional deterioration. Although ... | null | 1.614 | 211 | Cardiology and Cardiovascular Medicine | Medicine | 2,002 |
12,422,142 | Carotid artery intimal-medial thickness: indicator of atherosclerotic burden and response to risk factor modification. | American heart journal | Am Heart J | 144 | 5 | 10.1067/mhj.2002.124865 | eng | 2,002 | 11 | null | null | null | null | [BACKGROUND] A number of studies have used B-mode ultrasound to measure carotid intimal-medial thickness as an indicator of the severity of carotid atherosclerosis. [METHODS] We reviewed the available data on carotid intimal-medial thickness in defining severity of atherosclerosis, with the use of high-quality studies ... | null | 1.614 | 211 | Cardiology and Cardiovascular Medicine | Medicine | 2,002 |
12,420,041 | Functional status and quality of life following non-Q wave myocardial infarction. | The Canadian journal of cardiology | Can J Cardiol | 18 | 10 | null | eng | 2,002 | 10 | null | null | null | null | [OBJECTIVE] To review the literature on the management of non-Q wave myocardial infarction (NQWMI) with regard to functional status and quality of life outcomes. [BACKGROUND] Recent trials have raised the question of whether all patients with NQWMI should undergo an early routine invasive investigation versus a noninva... | null | 0.476 | 118 | Cardiology and Cardiovascular Medicine | Medicine | 2,002 |
12,419,451 | Application of constrained least-squares techniques to IMRT treatment planning. | International journal of radiation oncology, biology, physics | Int J Radiat Oncol Biol Phys | 54 | 4 | 10.1016/s0360-3016(02)03810-5 | eng | 2,002 | 11 | 15 | null | null | null | [PURPOSE] The purpose of this work was to apply the method of constrained least-squares to inverse treatment planning and to explore its potential for providing a fast interactive planning environment for intensity-modulated radiation therapy (IMRT). [METHODS AND MATERIALS] The description of the dose inside a patient ... | null | 1.712 | 286 | Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging | Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy | 2,002 |
12,419,161 | Effects of tetracycline-controlled antisense bcl-2 expression on the growth and apoptosis of human neuroblastoma cell line SK-N-MC. | Zhonghua bing li xue za zhi = Chinese journal of pathology | Zhonghua Bing Li Xue Za Zhi | 31 | 2 | null | eng | 2,002 | 4 | null | null | null | null | [OBJECTIVE] To study the effects of tetracycline-controlled antisense bcl-2 expression on the growth and apoptosis of human neuroblastoma cell line SK-N-MC and the related mechanisms. [METHODS] The tetracycline-controlled antisense bcl-2 expressing vector PUCCOMB1(CMV)/Asbcl-2 was constructed by inserting a 0.6 kb frag... | null | null | null | null | null | null |
12,519,653 | Areca nut, energy metabolism and hunger in Asian men. | Annals of human biology | Ann Hum Biol | 30 | 1 | 10.1080/03014460210157448 | eng | 2,003 | null | null | null | null | null | [BACKGROUND] The nut of the Areca catechu palm has long been attributed effects on hunger and the digestive process. [OBJECTIVES] The objectives were to assess experimentally effects of areca nut on fasting and postprandial energy metabolism, substrate utilization and hunger. [SUBJECTS AND METHODS] Two randomized, plac... | null | 0.47 | 70 | Aging; Public Health, Environmental and Occupational Health; Epidemiology; Genetics; Physiology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,003 |
12,519,432 | Expression levels of H-type alpha(1,2)-fucosyltransferase gene and histo-blood group ABO gene corresponding to hematopoietic cell differentiation. | Transfusion | Transfusion | 43 | 1 | 10.1046/j.1537-2995.2003.00277.x | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND] The expression of ABO antigens on the surface of RBCs is regulated by ABO gene-encoded ABO transferase activity after the formation of the H antigen. The molecular mechanisms that control the expression of the ABO blood group antigens along with erythroid differentiation are one of the most important subje... | null | 0.952 | 153 | Hematology; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,003 |
12,519,315 | Tissue factor pathway inhibitor (TFPI) release after heparin stimulation is increased in Type 1 diabetic patients with albuminuria. | Diabetic medicine : a journal of the British Diabetic Association | Diabet Med | 20 | 1 | 10.1046/j.1464-5491.2003.00786.x | eng | 2,003 | 1 | null | null | null | null | [AIMS] To study heparin-stimulated TFPI release in relation to complications in Type 1 diabetic patients. [SUBJECTS AND METHODS] Nineteen uncomplicated Type 1 diabetic patients (group I) were compared with 18 patients with retinopathy (group II), and nine patients with retinopathy and albuminuria (group III). Blood sam... | null | 0.961 | 171 | Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,003 |
12,519,231 | Preoperative assessment of hepatic function: Utility of a new convenient two-compartment model analysis using galactosyl human serum albumin scintigraphy. | Journal of gastroenterology and hepatology | J Gastroenterol Hepatol | 18 | 1 | 10.1046/j.1440-1746.2003.02920.x | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND AND AIM] Preoperative hepatic function was evaluated using technetium-99 m-diethylenetriaminepenta-acetic acid-galactosyl-human serum albumin (Tc-GSA) and a scintillation camera to detect hepatic Tc-GSA uptake by the asialoglycoprotein receptor. [METHODS] Sixty-two preoperative patients with liver cancer, i... | null | 0.579 | 156 | Gastroenterology; Hepatology | Medicine | 2,003 |
12,519,048 | Behçet's disease: part of the differential diagnosis of the ulcerative vulva. | Clinical and experimental obstetrics & gynecology | Clin Exp Obstet Gynecol | 29 | 3 | null | eng | 2,002 | null | null | null | null | null | [BACKGROUND] Behçet's disease is a heterogeneous pathological entity of unknown etiology, most of the time affecting many organs concurrently. [CASES] We report two cases of women who presented with ulcerations of the vulvar area as the first symptom, highlighting the diagnostic difficulties that were encountered until... | null | null | null | null | null | null |
12,518,376 | A prospective cohort study determining the prevalence of thrombotic events in children with acute lymphoblastic leukemia and a central venous line who are treated with L-asparaginase: results of the Prophylactic Antithrombin Replacement in Kids with Acute Lymphoblastic Leukemia Treated with Asparaginase (PARKAA) Study. | Cancer | Cancer | 97 | 2 | 10.1002/cncr.11042 | eng | 2,003 | 1 | 15 | null | null | null | [BACKGROUND] Thrombotic events (TEs) are serious secondary complications in children with acute lymphoblastic leukemia (ALL) who receive L-asparaginase (ASP) therapy; however, the prevalence of TEs has not been established. The primary objective of the Prophylactic Antithrombin Replacement in Kids with Acute Lymphoblas... | null | 1.864 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,003 |
12,518,182 | Practical considerations for the use of nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 inhibitors in hypertension and kidney disease. | The Canadian journal of cardiology | Can J Cardiol | 18 | 12 | null | eng | 2,002 | 12 | null | null | null | null | [BACKGROUND] Selective cyclo-oxygenase (COX)-2 inhibitors (coxibs) produce the beneficial effects of nonsteroidal anti-inflammatory drugs (NSAIDs) while sparing the COX-1-mediated adverse effects on platelets and the gastrointestinal system. However, due to the presence of constitutive COX-2 in the human kidney, coxibs... | null | 0.476 | 118 | Cardiology and Cardiovascular Medicine | Medicine | 2,002 |
12,518,126 | Cost-effectiveness of pancreatic cancer screening in familial pancreatic cancer kindreds. | Gastrointestinal endoscopy | Gastrointest Endosc | 57 | 1 | 10.1067/mge.2003.28 | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND] Endoscopic screening of families predisposed to pancreatic cancer is increasingly used, but the cost-effectiveness of screening is unknown. [METHODS] A decision analysis was used to compare one-time screening for pancreatic dysplasia with EUS to no screening in a hypothetical cohort of 100 members of famil... | null | 1.133 | 236 | Gastroenterology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,003 |
12,517,552 | Impact of antireflux operation on columnar-lined esophagus. | Journal of the American College of Surgeons | J Am Coll Surg | 196 | 1 | 10.1016/s1072-7515(02)01502-8 | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND] The effect of antireflux operation on the natural history of columnar-lined esophagus (CLE) is not fully understood. The aim of this study was to assess a single center's experience and review the literature on the impact of antireflux operation on CLE without high-grade dysplasia. [STUDY DESIGN] The medic... | null | 1.074 | 212 | Surgery | Medicine | 2,003 |
12,516,904 | Cigarette smoking and hearing loss: lessons from the young adult periodic examinations in Israel (YAPEIS) database. | The Israel Medical Association journal : IMAJ | Isr Med Assoc J | 4 | 12 | null | eng | 2,002 | 12 | null | null | null | null | [BACKGROUND] Some studies have indicated a possible link between cigarette smoking and hearing loss. [OBJECTIVES] To analyze the association between smoking and hearing loss, other than that induced by noise, and to characterize the type of HL impairment found in smokers. [METHODS] We conducted a retrospective cross-se... | null | null | null | null | null | null |
12,516,795 | The influence of head movement on the accuracy of a rapid pointing task. | Optometry (St. Louis, Mo.) | Optometry | 73 | 11 | null | eng | 2,002 | 11 | null | null | null | null | [BACKGROUND] Eye-hand coordination contributes to sports performance. The positive effect of head movement on the accuracy of eye-hand coordination of some subjects has been demonstrated for self-paced or single tasks, but not for rapid, repetititive tasks, such as those sometimes required in sports. The purpose of thi... | null | null | null | null | null | null |
12,516,653 | T and B lymphocyte subsets in patients with unexplained recurrent spontaneous abortion: IVIG versus placebo treatment. | American journal of reproductive immunology (New York, N.Y. : 1989) | Am J Reprod Immunol | 48 | 5 | 10.1034/j.1600-0897.2002.01010.x | eng | 2,002 | 11 | null | null | null | null | [PROBLEM] To investigate circulating lymphocyte subsets in women with recurrent spontaneous abortion (RSA) in relation to pregnancy outcome and to treatment with intravenous immunoglobulin (IVIG). [METHOD OF STUDY] Forty-one women with a history of unexplained RSA were examined during first trimester of pregnancy befor... | null | 0.669 | 119 | Obstetrics and Gynecology; Reproductive Medicine; Immunology and Allergy; Immunology | Immunology and Microbiology; Medicine | 2,002 |
12,516,327 | Uterine rupture in an unscarred uterus after application of fundal pressure. A case report. | The Journal of reproductive medicine | J Reprod Med | 47 | 12 | null | eng | 2,002 | 12 | null | null | null | null | [BACKGROUND] Rupture of an unscarred uterus is rare, with a reported incidence of 1 in 8,000-15,000 pregnancies. We report a case occurring during labor. [CASE] A 33-year-old woman, gravida 3, para 0, abortion 2, was admitted at 40 weeks' gestation with ruptured membranes. Fundal pressure was applied during delivery du... | null | null | null | null | null | null |
12,516,010 | Urinary incontinence in the geriatric population. | The Mount Sinai journal of medicine, New York | Mt Sinai J Med | 70 | 1 | null | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND] Urinary incontinence is a widespread, yet potentially treatable, problem in the geriatric population. [METHODS] We reviewed the geriatric and urologic literature to provide an update on the definition, diagnosis, and treatment of geriatric urinary incontinence. [RESULTS] Urinary incontinence affects 15-30%... | null | null | null | null | null | null |
12,515,872 | Impact of whole-body 18F-FDG PET on staging and managing patients for radiation therapy. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine | J Nucl Med | 44 | 1 | null | eng | 2,003 | 1 | null | null | null | null | [UNLABELLED] Whole-body PET with (18)F-FDG has proven to be a very effective imaging modality for staging of malignant tumors. This study was performed to evaluate the impact of (18)F-FDG PET on staging and managing patients for radiation therapy. [METHODS] The treatment records of 202 consecutive patients (98 male, 10... | null | 1.475 | 247 | Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,003 |
12,514,694 | Evidence-based emergency medicine. Update: do ophthalmic nonsteroidal anti-inflammatory drugs reduce the pain associated with simple corneal abrasion without delaying healing? | Annals of emergency medicine | Ann Emerg Med | 41 | 1 | 10.1067/mem.2003.38 | eng | 2,003 | 1 | null | null | null | null | [INTRODUCTION] Some studies have suggested that ophthalmic nonsteroidal anti-inflammatory drugs (NSAIDs) decrease the pain associated with corneal abrasions without impairing healing. This evidence-based emergency medicine (EBEM) critical appraisal reviews the literature, including additional studies appearing since th... | null | 1.212 | 178 | Emergency Medicine | Medicine | 2,003 |
12,514,438 | Antimicrobial susceptibilities of Neisseria gonorrhoeae strains isolated in Java, Indonesia. | Sexually transmitted diseases | Sex Transm Dis | 30 | 1 | 10.1097/00007435-200301000-00006 | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND] Despite the rapid spread of antibiotic resistance in gonococci all over Southeast Asia, there is only limited surveillance for antibiotic susceptibility in Indonesia. [GOAL] This study was undertaken to determine the frequency and diversity of antimicrobial resistance in gonococcal isolates from cohorts of... | null | 1.26 | 115 | Dermatology; Infectious Diseases; Microbiology; Public Health, Environmental and Occupational Health | Medicine | 2,003 |
12,514,421 | Agreement analysis of variables involved in lipodystrophy syndrome definition in HIV-infected patients. | Journal of acquired immune deficiency syndromes (1999) | J Acquir Immune Defic Syndr | 32 | 1 | 10.1097/00126334-200301010-00015 | eng | 2,003 | 1 | 1 | null | null | null | [BACKGROUND] Lipodystrophy studies in HIV-infected patients have usually defined abnormalities in body fat by clinical evaluation and patient questionnaires. Despite the risk for bias with these subjective approaches, agreement analysis among the large number of variables employed was seldom performed. [OBJECTIVE] To a... | null | 1.889 | 176 | Infectious Diseases; Pharmacology | Medicine | 2,003 |
12,514,418 | HIV knowledge and risk factors among men who have sex with men in Ho Chi Minh City, Vietnam. | Journal of acquired immune deficiency syndromes (1999) | J Acquir Immune Defic Syndr | 32 | 1 | 10.1097/00126334-200301010-00012 | eng | 2,003 | 1 | 1 | null | null | null | [OBJECTIVES] To describe health risk behavior, knowledge, and attitudes about HIV/AIDS and its prevention in men who have sex with men (MSM) in Ho Chi Minh City (HCMC), Vietnam. [METHODS] A cross-sectional survey of 219 MSM using a standardized questionnaire. [RESULTS] Men who have sex with men were easy to locate and ... | null | 1.889 | 176 | Infectious Diseases; Pharmacology | Medicine | 2,003 |
12,514,388 | Effect of chronic and short-term erythropoietin treatment on random flap survival in rats: an experimental study. | The Laryngoscope | Laryngoscope | 113 | 1 | 10.1097/00005537-200301000-00016 | eng | 2,003 | 1 | null | null | null | null | [OBJECTIVE] The use of perioperative erythropoietin (EPO) therapy is gaining popularity to avoid blood transfusion and correct anemia in head and neck cancer surgery. The purpose of the study was to determine the effect of various doses and durations of EPO treatment on random flap survival. [STUDY DESIGN] A McFarlane ... | null | 1.415 | 183 | Otorhinolaryngology | Medicine | 2,003 |
12,514,144 | Desmopressin does not decrease blood loss and transfusion requirements in patients undergoing hepatectomy. | Canadian journal of anaesthesia = Journal canadien d'anesthesie | Can J Anaesth | 50 | 1 | 10.1007/BF03020180 | eng | 2,003 | 1 | null | null | null | null | [PURPOSE] To determine the effects of desmopressin on coagulation and blood loss in patients undergoing elective partial hepatectomy. [METHODS] A randomized, controlled and double-blind study on 59 patients who received either 0.3 micro g x kg(-1) of desmopressin or an equal volume of normal saline (control) infused in... | null | null | null | null | null | null |
12,512,765 | Socioeconomic and racial/ethnic disparities in unintended pregnancy among postpartum women in California. | Maternal and child health journal | Matern Child Health J | 6 | 4 | 10.1023/a:1021158016268 | eng | 2,002 | 12 | null | null | null | null | [OBJECTIVE] We examined social disparities in unintended pregnancy among postpartum women to better understand 1) the role of socioeconomic factors in racial/ethnic disparities and 2) factors that might explain both socioeconomic and racial/ethnic disparities in the risk for unintended pregnancy among women who give bi... | null | 0.566 | 109 | Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health; Public Health, Environmental and Occupational Health; Epidemiology | Medicine | 2,002 |
12,512,243 | Patterns and perceptions of complementary and alternative medicine (CAM) among leukaemia patients visiting haematology clinic of a north Indian tertiary care hospital. | Pharmacoepidemiology and drug safety | Pharmacoepidemiol Drug Saf | 11 | 8 | 10.1002/pds.782 | eng | 2,002 | 12 | null | null | null | null | [PURPOSE] The use of complementary and alternative medicine (CAM) in cancer treatments is widespread with substantial number of patients deserting conventional cancer therapies in favour of unproven methods. The present study aimed at discovering the prevalence of use of CAM cancer therapies in leukaemia patients visit... | null | 0.239 | 113 | Pharmacology; Epidemiology | Medicine | 2,002 |
12,511,156 | Laparoscopic vs conventional ileocolectomy for primary Crohn disease. | Archives of surgery (Chicago, Ill. : 1960) | Arch Surg | 138 | 1 | 10.1001/archsurg.138.1.76 | eng | 2,003 | 1 | null | null | null | null | [HYPOTHESIS] Laparoscopic ileocolectomy can reduce the length of hospital stay and hospital charges compared with conventional surgery in the treatment of primary Crohn disease. [DESIGN] Nonrandomized, comparative, retrospective analysis of a prospective database. [SETTING] University hospital tertiary care center for ... | null | null | null | null | null | null |
12,512,038 | Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan. | Gastroenterology | Gastroenterology | 124 | 1 | 10.1053/gast.2003.50019 | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND AND AIMS] The NOD2 variants R702W, G908R, and L1007fsinsC are strongly associated with Crohn's disease (CD) in both European and American populations, but whether this susceptibility extends to all ethnic groups remains unknown. Except for the L1007fsinsC mutation, which produces a truncated NOD2 protein, t... | null | 3.421 | 482 | Gastroenterology | Medicine | 2,003 |
12,511,748 | Plasma metalloproteinase-9 concentration predicts hemorrhagic transformation in acute ischemic stroke. | Stroke | Stroke | 34 | 1 | null | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND AND PURPOSE] Matrix metalloproteinase-9 (MMP-9) activity has been associated with hemorrhagic transformation (HT) in experimental models of cerebral ischemia. Our aim was to investigate the relationship between MMP-9 concentrations in blood within 24 hours of stroke onset and subsequent HT of cerebral infar... | null | 2.852 | 370 | Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience | Medicine; Neuroscience; Nursing | 2,003 |
12,511,719 | Inhaled short acting beta agonist use in COPD and the risk of acute myocardial infarction. | Thorax | Thorax | 58 | 1 | 10.1136/thorax.58.1.43 | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND] A recent study found that short acting beta agonists used in the treatment of asthma and chronic obstructive pulmonary disease (COPD) may increase the risk of acute myocardial infarction. We investigated this hypothesis in patients with COPD already at high risk of cardiac disease. [METHODS] The Saskatchew... | null | 1.286 | 259 | Pulmonary and Respiratory Medicine | Medicine | 2,003 |
12,511,671 | Evaluation of liver diffusion isotropy and characterization of focal hepatic lesions with two single-shot echo-planar MR imaging sequences: prospective study in 66 patients. | Radiology | Radiology | 226 | 1 | 10.1148/radiol.2261011904 | eng | 2,003 | 1 | null | null | null | null | [PURPOSE] To (a) evaluate liver diffusion isotropy, (b) compare two diffusion-weighted magnetic resonance (MR) imaging sequences for the characterization of focal hepatic lesions by using two or four b values, and (c) determine an apparent diffusion coefficient (ADC) threshold value to differentiate benign from maligna... | null | 2.544 | 346 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,003 |
12,510,728 | Management of scleral rupture during retinal detachment surgery: a case report. | European journal of ophthalmology | Eur J Ophthalmol | 12 | 6 | 10.1177/112067210201200619 | eng | 2,002 | null | null | null | null | null | [PURPOSE] Rupture of the sclera occurring during retinal detachment surgery is generally associated with unfavourable anatomic and visual outcomes. Re-operation after a failed scleral buckle procedure and pre-existing scleral thinning are considered the main risk factors for scleral rupture. [CASE REPORT] We describe t... | null | 0.497 | 69 | Medicine; Ophthalmology | Medicine | 2,002 |
12,510,694 | Improvement in papilledema and visual loss after endovascular stent placement in dural sinus thrombosis. | Neuro-ophthalmology (Aeolus Press) | Neuroophthalmology | 26 | 2 | 10.1076/noph.26.2.85.10310 | eng | 2,001 | 9 | null | null | null | null | [OBJECTIVE] To report two cases of cerebral venous sinus thrombosis with papilledema and visual loss that improved after endovascular stent placement. [MATERIALS AND METHODS] Retrospective case series from a tertiary ophthalmic center. [RESULTS] Two cases of venous sinus occlusion treated with angioplasty and stenting ... | null | null | null | null | null | null |
12,508,959 | Th1/Th2 balance in childhood idiopathic nephrotic syndrome. | Clinical nephrology | Clin Nephrol | 58 | 6 | 10.5414/cnp58393 | eng | 2,002 | 12 | null | null | null | null | [AIMS] In view of the conflicting evidence of helper T cell type 1 (Th1) or type 2 (Th2) pattern of cytokine synthesis in childhood idiopathic nephrotic syndrome (INS) this study examined the balance of Th1 and Th2 which are characterized by intracellular cytokine production of interferon-gamma (IFNgamma) and interleuk... | null | null | null | null | null | null |
12,508,694 | Independent prognostic value of hormone receptor expression and S-phase fraction in advanced breast cancer. | Analytical and quantitative cytology and histology | Anal Quant Cytol Histol | 24 | 6 | null | eng | 2,002 | 12 | null | null | null | null | [OBJECTIVE] TO assess the prognostic value of immunocytochemically assessed hormone receptor expression and DNA flow cytometry data in advanced breast cancer. [STUDY DESIGN] This prospective study with long-term follow-up evaluated the above parameters in relation to overall survival in 392 patients with advanced breas... | null | null | null | null | null | null |
12,508,690 | DNA cytometry in pleomorphic adenomas with cytologic atypia. | Analytical and quantitative cytology and histology | Anal Quant Cytol Histol | 24 | 6 | null | eng | 2,002 | 12 | null | null | null | null | [OBJECTIVE] To investigate the nuclear DNA content of pleomorphic adenomas with cytologic atypia. [STUDY DESIGN] Analysis was performed on new, fuchsin-stained samples of 10 selected cases of pleomorphic adenoma with cytologic atypia. Morphometric analysis was done by a computer-assisted image cytometry system and cons... | null | null | null | null | null | null |
12,507,741 | The role of cyclothymia in atypical depression: toward a data-based reconceptualization of the borderline-bipolar II connection. | Journal of affective disorders | J Affect Disord | 73 | 1-2 | 10.1016/s0165-0327(02)00329-4 | eng | 2,003 | 1 | null | null | null | null | [OBJECTIVE] Recent data, including our own, indicate significant overlap between atypical depression and bipolar II. Furthermore, the affective fluctuations of patients with these disorders are difficult to separate, on clinical grounds, from cyclothymic temperamental and borderline personality disorders. The present a... | null | 1.879 | 245 | Clinical Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,003 |
12,507,737 | Bipolar II with and without cyclothymic temperament: "dark" and "sunny" expressions of soft bipolarity. | Journal of affective disorders | J Affect Disord | 73 | 1-2 | 10.1016/s0165-0327(02)00320-8 | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND] In the present report deriving from the French national multi-site EPIDEP study, we focus on the characteristics of Bipolar II (BP-II), divided on the basis of cyclothymic temperament (CT). In our companion article (Hantouche et al., this issue), we found that this temperament in its self-rated version cor... | null | 1.879 | 245 | Clinical Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,003 |
12,507,126 | Staged stent-assisted angioplasty for symptomatic intracranial vertebrobasilar artery stenosis. | Journal of neurosurgery | J Neurosurg | 97 | 6 | 10.3171/jns.2002.97.6.1294 | eng | 2,002 | 12 | null | null | null | null | [OBJECT] Medically refractory symptomatic vertebrobasilar atherosclerotic disease has a poor prognosis. Studies have shown that longer (> or = 10 mm), eccentric, high-grade (> 70%) stenoses portend increased procedure-related morbidity. The authors reviewed their experience to determine whether a staged procedure consi... | null | 1.429 | 244 | Neurology; Surgery | Medicine | 2,002 |
12,506,593 | Randomised trials in the South African Medical Journal, 1948-1997. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde | S Afr Med J | 92 | 11 | null | eng | 2,002 | 11 | null | null | null | null | [OBJECTIVE] To describe randomised controlled trials (RCTs) published in the South African Medical Journal (SAMJ) over a 50-year period from 1948 to 1997 with regard to number, topic and quality. [METHODS] We hand searched all issues of the SAMJ published during the study period to identify all published RCTs. [OUTCOME... | null | null | null | null | null | null |
12,506,298 | Correlation of blood volume values and pulmonary artery catheter measurements. | Saudi medical journal | Saudi Med J | 23 | 11 | null | eng | 2,002 | 11 | null | null | null | null | [OBJECTIVE] To correlate the values generated by direct total blood volume measurement with pulmonary artery catheter parameters and commonly used laboratory values in the management of critically ill patients. [METHODS] This study was carried out at the Lutheran Medical Center, Brooklyn, New York, United States of Ame... | null | null | null | null | null | null |
12,506,099 | Identification of the gene and the mutation responsible for the mouse nob phenotype. | Investigative ophthalmology & visual science | Invest Ophthalmol Vis Sci | 44 | 1 | 10.1167/iovs.02-0501 | eng | 2,003 | 1 | null | null | null | null | [PURPOSE] The available evidence indicates that the naturally occurring mouse mutant nob (no b-wave) provides an animal model for the complete form of human X-linked congenital stationary night blindness (CSNB1). The goals of the present study were to identify the nob gene defect, to characterize the expression pattern... | null | null | null | null | null | null |
12,506,075 | Phospholipase A2 activity in normal and Staphylococcus aureus-infected rabbit eyes. | Investigative ophthalmology & visual science | Invest Ophthalmol Vis Sci | 44 | 1 | 10.1167/iovs.02-0548 | eng | 2,003 | 1 | null | null | null | null | [PURPOSE] To quantify phospholipase A(2) (PLA(2)) activity in normal rabbit eyes and in eyes with Staphylococcus aureus keratitis. [METHODS] PLA(2) was assayed by the killing of S. aureus at 33 degrees C or by the release of arachidonic acid from S. aureus labeled with radioactive oleic acid. Rabbit corneas were intras... | null | null | null | null | null | null |
12,506,059 | The cell-layer- and cell-type-specific distribution of GalNAc-transferases in the ocular surface epithelia is altered during keratinization. | Investigative ophthalmology & visual science | Invest Ophthalmol Vis Sci | 44 | 1 | 10.1167/iovs.02-0181 | eng | 2,003 | 1 | null | null | null | null | [PURPOSE] It has been hypothesized that the biosynthesis of O-linked glycans on proteins, particularly on the highly O-glycosylated mucins, by the corneal and conjunctival epithelium is necessary for the protection and maintenance of a healthy ocular surface. The initial step in O-glycosylation is the enzymatic additio... | null | null | null | null | null | null |
12,506,056 | Fenestrations enhance tear mixing under silicone-hydrogel contact lenses. | Investigative ophthalmology & visual science | Invest Ophthalmol Vis Sci | 44 | 1 | 10.1167/iovs.02-0348 | eng | 2,003 | 1 | null | null | null | null | [PURPOSE] Extended wear of conventional hydrogel soft contact lenses (SCLs) is associated with adverse ocular responses. Some of these ocular events are thought to result from inadequate tear mixing in the postlens tear film (PoLTF). Therefore, strategies to increase tear mixing may improve the safety of extended-wear ... | null | null | null | null | null | null |
12,505,813 | Untreated initial psychosis: relation to cognitive deficits and brain morphology in first-episode schizophrenia. | The American journal of psychiatry | Am J Psychiatry | 160 | 1 | 10.1176/appi.ajp.160.1.142 | eng | 2,003 | 1 | null | null | null | null | [OBJECTIVE] Studies of patients experiencing their first episode of psychosis have demonstrated that they typically remain undiagnosed and untreated for 1-2 years. It has been postulated that prolonged untreated psychosis may have serious effects: poor response to neuroleptic medications, poor clinical outcomes, and di... | null | 4.518 | 405 | Psychiatry and Mental Health | Medicine | 2,003 |
12,505,729 | Modeling individual variation in biomarker response to combination immunosuppression with stimulated lymphocyte responses-potential clinical implications. | Journal of immunological methods | J Immunol Methods | 272 | 1-2 | 10.1016/s0022-1759(02)00326-5 | eng | 2,003 | 1 | 15 | null | null | null | [BACKGROUND] In mitogen-stimulated lymphocyte responses (sLR), cytokines and cell-surface receptors in peripheral human blood lymphocytes (PBL) are sensitive to cyclosporine (CsA), and can predict its in vivo effect with pharmacodynamic (PD) modeling. This is not known for multiple-agent combinations. [METHODS] Twenty-... | null | 1.298 | 151 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,003 |
12,505,114 | Association of educational status with heart rate recovery: a population-based propensity analysis. | The American journal of medicine | Am J Med | 113 | 8 | 10.1016/s0002-9343(02)01324-4 | eng | 2,002 | 12 | 1 | null | null | null | [PURPOSE] An abnormally attenuated heart rate recovery after exercise is a predictor of mortality that is thought to reflect decreased parasympathetic activity. Lower educational level may be associated with automatic imbalance. We sought to assess the association of educational level with heart rate recovery. [SUBJECT... | null | 1.979 | 262 | Medicine | Medicine | 2,002 |
12,504,627 | Weekly low-dose carboplatin and paclitaxel in the treatment of recurrent ovarian and peritoneal cancer. | Gynecologic oncology | Gynecol Oncol | 88 | 1 | 10.1006/gyno.2002.6859 | eng | 2,003 | 1 | null | null | null | null | [OBJECTIVES] Weekly paclitaxel alone has moderate activity in the salvage treatment of recurrent ovarian cancer and is associated with a favorable toxicity profile. Combination paclitaxel and carboplatin is a well-established first-line regimen for ovarian cancer. The purpose of this study was to evaluate weekly low-do... | null | 1.087 | 192 | Obstetrics and Gynecology; Oncology | Medicine | 2,003 |
12,504,036 | Evidence-based estimate of appropriate radiotherapy utilization rate for prostate cancer. | International journal of radiation oncology, biology, physics | Int J Radiat Oncol Biol Phys | 55 | 1 | 10.1016/s0360-3016(02)03866-x | eng | 2,003 | 1 | 1 | null | null | null | [PURPOSE] Current estimates of the proportion of cancer patients who will require radiotherapy (RT) are based almost entirely on expert opinion. The objective of this study was to use an evidence-based approach to estimate the proportion of incident cases of prostate cancer that should receive RT at any point in the ev... | null | 2.258 | 286 | Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging | Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy | 2,003 |
12,504,034 | Analysis of in-field control and late toxicity for adults with early-stage Hodgkin's disease treated with chemotherapy followed by radiotherapy. | International journal of radiation oncology, biology, physics | Int J Radiat Oncol Biol Phys | 55 | 1 | 10.1016/s0360-3016(02)03915-9 | eng | 2,003 | 1 | 1 | null | null | null | [PURPOSE] We analyzed in-field (IF) control in adults with early-stage Hodgkin's disease who received chemotherapy followed by radiotherapy (RT) in terms of the (1) chemotherapeutic regimen used and number of cycles delivered, (2) response to chemotherapy, and (3) initial tumor size. Cardiac toxicity and second maligna... | null | 2.258 | 286 | Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging | Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy | 2,003 |
12,503,037 | An analysis of prognostic factors and the five-year survival rate in childhood acute lymphoblastic leukemia. | Medical science monitor : international medical journal of experimental and clinical research | Med Sci Monit | 8 | 12 | null | eng | 2,002 | 12 | null | null | null | null | [BACKGROUND] Acute Lymphoblastic Leukemia (ALL) is the most common malignancy in childhood. With newer drug protocols the five-year survival rate is now close to 80%. Various factors have been reported to be important for prognosis and should be considered when planning [MATERIAL/METHODS] In a cross-sectional study, pr... | null | 0.186 | 107 | Medicine | Medicine | 2,002 |
12,503,027 | Actions of paracetamol on cyclooxygenases in tissue and cell homogenates of mouse and rabbit. | Medical science monitor : international medical journal of experimental and clinical research | Med Sci Monit | 8 | 12 | null | eng | 2,002 | 12 | null | null | null | null | [BACKGROUND] Paracetamol is a potent analgesic and antipyretic drug, but has only weak anti-inflammatory activity. Unlike aspirin-like drugs, paracetamol does not damage the stomach mucosa or inhibit the aggregation of platelets. The analgesic action of paracetamol is on the central nervous system. In vitro, paracetamo... | null | 0.186 | 107 | Medicine | Medicine | 2,002 |
12,502,958 | Annular crystalline keratopathy in association with immunoglobulin therapy for pyoderma gangrenosum. | Cornea | Cornea | 22 | 1 | 10.1097/00003226-200301000-00021 | eng | 2,003 | 1 | null | null | null | null | [PURPOSE] To report on a patient with a clinical presentation of annular crystalline keratopathy after immunoglobulin therapy for pyoderma gangrenosum. [METHODS] Case report of a 6-year-old boy with biopsy-proven history of pyoderma gangrenosum who had undergone several cycles of systemic immunoglobulin therapy. The li... | null | 1.298 | 141 | Ophthalmology | Medicine | 2,003 |
12,502,664 | Life course influences on insulin resistance: findings from the British Women's Heart and Health Study. | Diabetes care | Diabetes Care | 26 | 1 | 10.2337/diacare.26.1.97 | eng | 2,003 | 1 | null | null | null | null | [OBJECTIVE] To assess the independent associations of a broad range of early life risk factors and adult obesity with adult insulin resistance. [RESEARCH DESIGN AND METHODS] This was a cross-sectional study of 1,394 women, aged 60-79 years, from 23 British towns. [RESULTS] There was a strong (independent of confounding... | null | 3.169 | 433 | Advanced and Specialized Nursing; Endocrinology, Diabetes and Metabolism; Internal Medicine | Medicine; Nursing | 2,003 |
12,502,138 | Vaccination for hepatitis A virus is not required for patients with chronic liver disease in India. | The National medical journal of India | Natl Med J India | 15 | 5 | null | eng | 2,002 | null | null | null | null | null | [BACKGROUND] Hepatitis A virus (HAV) vaccination is recommended worldwide for patients with chronic liver disease to prevent decompensation due to superinfection with HAV. India being endemic for HAV, the prevalence of pre-existing antibodies against HAV due to subclinical exposure to the virus in childhood among patie... | null | null | null | null | null | null |
12,501,074 | Aspirin consumption during the first trimester of pregnancy and congenital anomalies: a meta-analysis. | American journal of obstetrics and gynecology | Am J Obstet Gynecol | 187 | 6 | 10.1067/mob.2002.127376 | eng | 2,002 | 12 | null | null | null | null | [OBJECTIVE] The purpose of this study was to determine, on the basis of published reports, whether aspirin use during the first trimester of pregnancy is associated with an increased risk of congenital malformations. [STUDY DESIGN] We reviewed the literature for published studies that reported exposure to aspirin durin... | null | 1.509 | 274 | Obstetrics and Gynecology | Medicine | 2,002 |
12,501,073 | Fetal hepatic calcifications: prenatal diagnosis and outcome. | American journal of obstetrics and gynecology | Am J Obstet Gynecol | 187 | 6 | 10.1067/mob.2002.127899 | eng | 2,002 | 12 | null | null | null | null | [OBJECTIVE] The purpose of this study was to provide information on the causes and postnatal outcomes of fetal liver calcifications that were detected by ultrasound imaging. [STUDY DESIGN] Cases with fetal liver calcifications that were encountered between 1992 and 2001 were evaluated. A detailed fetal ultrasound imagi... | null | 1.509 | 274 | Obstetrics and Gynecology | Medicine | 2,002 |
12,501,065 | Cytometric features of cell nuclei of adenocarcinoma in situ and invasive adenocarcinoma of the cervix. | American journal of obstetrics and gynecology | Am J Obstet Gynecol | 187 | 6 | 10.1067/mob.2002.127906 | eng | 2,002 | 12 | null | null | null | null | [OBJECTIVE] The goal of this study was to characterize adenocarcinoma in situ (ACIS) and invasive adenocarcinoma (AdCa) of the cervix by using image histometric measurements of nuclear morphometric features. [STUDY DESIGN] Archival pathology slides and tissue blocks from 37 patients with ACIS, 18 with invasive AdCa, an... | null | 1.509 | 274 | Obstetrics and Gynecology | Medicine | 2,002 |
12,500,173 | Removal of dental amalgam and other metal alloys supported by antioxidant therapy alleviates symptoms and improves quality of life in patients with amalgam-associated ill health. | Neuro endocrinology letters | Neuro Endocrinol Lett | 23 | 5-6 | null | eng | 2,002 | null | null | null | null | null | [OBJECTIVES] The purpose of this study was to evaluate treatment of patients suffering from chronic ill health with a multitude of symptoms associated with metal exposure from dental amalgam and other metal alloys. [SETTING AND DESIGN] We included 796 patients in a retrospective study using a questionnaire about sympto... | null | null | null | null | null | null |
12,500,042 | Smoking, blood pressure and serum cholesterol-effects on 20-year mortality. | Epidemiology (Cambridge, Mass.) | Epidemiology | 14 | 1 | 10.1097/00001648-200301000-00010 | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND] To study the impact of smoking and blood pressure conditional on serum total cholesterol levels, we investigated the 20-year mortality risk associated with high systolic blood pressure (> or =140 mmHg) and smoking, at low (<5.2 mmol/Liter), medium (5.2-6.49mmol/Liter), and high (> or =6.5 mmol/Liter) serum... | null | 1.934 | 203 | Epidemiology | Medicine | 2,003 |
12,499,889 | Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen in stable kidney transplant recipients: a randomized, controlled study. | Transplantation | Transplantation | 74 | 12 | 10.1097/00007890-200212270-00015 | eng | 2,002 | 12 | 27 | null | null | null | [BACKGROUND] Long-term maintenance immunosuppression with cyclosporine (CsA) is associated with chronic transplant nephropathy and adverse effects on blood pressure and lipid profile. Several nonrandomized studies suggest that CsA might safely be withdrawn from immunosuppressive regimens containing mycophenolate mofeti... | null | 1.476 | 224 | Transplantation | Medicine | 2,002 |
12,499,332 | Serum lycopene concentrations and carotid atherosclerosis: the Kuopio Ischaemic Heart Disease Risk Factor Study. | The American journal of clinical nutrition | Am J Clin Nutr | 77 | 1 | 10.1093/ajcn/77.1.133 | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND] Interest in lycopene is growing rapidly following the recent publication of epidemiologic studies in which high circulating lycopene concentrations were associated with reductions in cardiovascular disease. Lycopene is one of the major carotenoids in the Western diet and is probably one of the protective f... | null | 2.664 | 390 | Medicine; Nutrition and Dietetics | Medicine; Nursing | 2,003 |
12,499,099 | Weekly low-dose docetaxel in advanced non-small cell lung cancer previously treated with two chemotherapy regimens. | Lung cancer (Amsterdam, Netherlands) | Lung Cancer | 39 | 1 | 10.1016/s0169-5002(02)00306-9 | eng | 2,003 | 1 | null | null | null | null | [BACKGROUND] The role of salvage chemotherapy in advanced non-small cell lung cancer (NSCLC) is still controversial, but the recent development of a number of active antineoplastic agents has created new possibilities for disease management. The aim of this study was to evaluate the activity and safety of weekly doceta... | null | 0.813 | 154 | Pulmonary and Respiratory Medicine; Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,003 |
12,498,842 | Evaluation of the prophylactic use of mitomycin-C to inhibit haze formation after photorefractive keratectomy. | Journal of cataract and refractive surgery | J Cataract Refract Surg | 28 | 12 | 10.1016/s0886-3350(02)01701-7 | eng | 2,002 | 12 | null | null | null | null | [PURPOSE] To evaluate the results of the prophylactic use of mitomycin-C to inhibit haze formation after excimer laser photorefractive keratectomy (PRK) for medium and high myopia in eyes that were not good candidates for laser in situ keratomileusis (LASIK). [SETTING] Carones Ophthalmology Center, Milan, Italy. [METHO... | null | 1.771 | 169 | Ophthalmology; Sensory Systems; Surgery | Medicine; Neuroscience | 2,002 |
12,498,604 | Comparison of nasalance scores obtained from the Nasometer and the NasalView. | The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association | Cleft Palate Craniofac J | 40 | 1 | 10.1597/1545-1569_2003_040_0040_consof_2.0.co_2 | eng | 2,003 | 1 | null | null | null | null | [OBJECTIVE] Nasalance scores obtained from the Nasometer and the NasalView were compared for five different sentences. [DESIGN] Vowel content was controlled in the design of the five stimulus sentences. One sentence was loaded with high-front vowels, one with high-back vowels, one with low-front vowels, one with low-ba... | null | 0.677 | 96 | Otorhinolaryngology; Oral Surgery | Dentistry; Medicine | 2,003 |
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