pmid
int64
10.6M
40.8M
title
stringlengths
14
606
journal_title
stringlengths
3
239
journal_iso
stringlengths
3
51
volume
stringlengths
1
207
issue
stringclasses
726 values
doi
stringlengths
5
66
language
stringclasses
1 value
pub_date_year
float64
2k
2.03k
pub_date_month
float64
1
12
pub_date_day
float64
1
31
article_date_year
float64
2k
2.03k
article_date_month
float64
1
12
article_date_day
float64
1
31
abstract_text
stringlengths
323
8.65k
keywords
stringlengths
2
1.73k
SJR
float64
0.1
26
H index
float64
0
1.23k
categories
stringlengths
6
264
areas
stringclasses
208 values
sjr_year_source
float64
2k
2.02k
34,985,717
Epidemiology and region-specific risk factors for low Apgar scores in China: a nationwide study.
World journal of pediatrics : WJP
World J Pediatr
18
2
10.1007/s12519-021-00497-y
eng
2,022
2
null
2,022
1
5
[BACKGROUND] Neonatal asphyxia is a serious public health issue. This study aimed to determine the epidemiology and region-specific risk factors for low Apgar scores, an important proxy for neonatal asphyxia, in China from 2015 to 2016. [METHODS] The China Labor and Delivery Survey was a multicenter cross-sectional stu...
Apgar score; China; Epidemiology; Risk factor
0.838
51
Pediatrics, Perinatology and Child Health
Medicine
2,022
34,985,029
Describing Nonfatal Intimate Partner Strangulation Presentation and Evaluation in a Community-Based Hospital: Partnerships Between the Emergency Department and In-House Advocates.
The Journal of head trauma rehabilitation
J Head Trauma Rehabil
37
1
10.1097/HTR.0000000000000742
eng
null
null
null
null
null
null
[OBJECTIVE] To describe characteristics of strangulation, and associated medical care, documentation, and injuries of women after nonfatal intimate partner strangulation (NF-IPS) who present for care to a community-based emergency department (ED) with an associated intimate partner violence (IPV) advocacy program betwe...
null
null
null
null
null
null
34,984,969
Characteristics of Newborns from Mothers with SARS-CoV-2 Infection in a Portuguese Hospital.
Acta medica portuguesa
Acta Med Port
34
10
10.20344/amp.16180
eng
2,021
10
1
2,021
10
1
[INTRODUCTION] Guidance for pregnant women has been particularly problematic since the beginning of the COVID-19 pandemic. The aim of this study was to describe the characteristics and outcomes of pregnant women with SARS-CoV-2 infection and their newborns. [MATERIAL AND METHODS] Case review of clinical records of preg...
Breast Feeding; Infant, Newborn; Pregnancy; Rooming-in Care; SARS-CoV-2
0.262
32
Medicine
Medicine
2,021
34,984,683
A novel adiponectin receptor agonist (AdipoAI) ameliorates type 2 diabetes-associated periodontitis by enhancing autophagy in osteoclasts.
Journal of periodontal research
J Periodontal Res
57
2
10.1111/jre.12969
eng
2,022
4
null
2,022
1
4
[BACKGROUND AND OBJECTIVE] Type 2 diabetes (T2D)-associated periodontitis is severe and refractory in many cases. Considered an inflammatory disease, T2D predisposes to periodontitis by increasing whole-body inflammation. One mechanism of increased inflammation is thatT2D is mediated by loss of production or function o...
Adiponectin receptor agonist; Diet-Induced Obesity; Periodontitis; Type 2 Diabetes; autophagy
0.816
102
Periodontics
Dentistry
2,022
34,984,628
A comprehensive enhanced depth imaging spectral-domain optical coherence tomography analysis of pseudoexfoliation spectrum from non-glaucomatous to advanced stage glaucoma in the aspect of Bruch's membrane opening-minimum rim width.
International ophthalmology
Int Ophthalmol
42
6
10.1007/s10792-021-02181-6
eng
2,022
6
null
2,022
1
5
[PURPOSE] To compare the correlations between lamina cribrosa (LC) and related structures with Bruch's membrane opening-minimum rim width (BMO-MRW) and retinal nerve fiber layer (RNFL) thickness in pseudoexfoliation syndrome (PXS) and different stages of pseudoexfoliation glaucoma (PXG). [METHODS] This prospective cros...
Bruch's; Lamina cribrosa depth; Lamina cribrosa thickness; Membrane opening-minimum rim width; Prelaminar tissue thickness; Pseudoexfoliation glaucoma; Pseudoexfoliation syndrome
0.587
57
Ophthalmology
Medicine
2,022
34,984,529
Variability between the trial and final implant measurements during the sensor-guided total knee arthroplasty.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Knee Surg Sports Traumatol Arthrosc
30
8
10.1007/s00167-021-06795-2
eng
2,022
8
null
2,022
1
4
[PURPOSE] Compartmental load-sensing technology has been used in the attempt to achieve optimal soft tissue balance during total knee arthroplasty (TKA). This study was conducted to investigate the validity of such use of intraoperative sensing technology. [METHODS] Ninety-three knees scheduled to undergo total knee ar...
Intraoperative load-sensing technology; Sensor; Soft tissue balance; Total knee arthroplasty; Validation study
1.789
160
Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,022
34,984,519
Radiologic-pathologic correlation of interstitial lung abnormalities and predictors for progression and survival.
European radiology
Eur Radiol
32
4
10.1007/s00330-021-08378-8
eng
2,022
4
null
2,022
1
5
[OBJECTIVES] To evaluate radiologic and histologic correlations for interstitial lung abnormalities (ILAs) and to investigate radiologic or pathologic features contributing to disease progression and mortality. [METHODS] From 268 patients who underwent surgical lung biopsy between January 2004 and April 2019, 45 patien...
Disease progression; Lung diseases, interstitial; Pathology; Survival analysis; Tomography, X-ray computed
1.733
182
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
34,984,011
Comprehensive Genomic Survey of Antimicrobial-Resistance Bacteria in the Sewage Tank Replacement with Hospital Relocation.
Infection and drug resistance
Infect Drug Resist
14
null
10.2147/IDR.S336418
eng
2,021
null
null
2,021
12
20
[BACKGROUND] Excrement containing antimicrobial-resistant bacteria (ARB) is discharged from the hospital sewage through wastewater treatment plants (WWTP) into rivers, increasing the antimicrobial resistance (AMR) burden on the environment. [PURPOSE] We illustrate the contamination of hospital sewage tanks with ARB har...
antimicrobial resistance; antimicrobial resistance gene; hospital sewage; metagenome analysis; residual antimicrobial reagents; whole genome sequencing
0.944
74
Pharmacology; Pharmacology; Infectious Diseases
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,021
34,983,888
Care Coordination Processes in Transitional Care for Patients With Heart Failure: An Integrative Review Through a Social Network Lens.
The Journal of cardiovascular nursing
J Cardiovasc Nurs
37
6
10.1097/JCN.0000000000000872
eng
null
null
null
2,022
1
5
[BACKGROUND] Transitional care components are well studied, but their coordination has not been systematically reviewed. Viewing transitional care through a social network framework can focus attention on processes leading to information and relationship transferal to ensure continuity and may lead to new strategies to...
null
null
null
null
null
null
34,983,770
Association between hormone replacement therapy and carpal tunnel syndrome: a nationwide population-based study.
BMJ open
BMJ Open
12
1
10.1136/bmjopen-2021-055139
eng
2,022
1
4
2,022
1
4
[OBJECTIVE] Carpal tunnel syndrome (CTS) is the most common compressive focal mononeuropathy, and the increased incidence in postmenopausal and pregnant women suggests its association with oestrogen. The objective of this study is to evaluate the relationship between hormone replacement therapy (HRT) and the occurrence...
epidemiology; gynaecology; neurology; neuromuscular disease
1.059
176
Medicine
Medicine
2,022
34,983,612
Postmarketing safety of orphan drugs: a longitudinal analysis of the US Food and Drug Administration database between 1999 and 2018.
Orphanet journal of rare diseases
Orphanet J Rare Dis
17
1
10.1186/s13023-021-02166-9
eng
2,022
1
4
2,022
1
4
[BACKGROUND] Information about the specific regulatory environment of orphan drugs is scarce and inconsistent. Uncertainties surrounding the postmarketing long-term safety of orphan drugs remain. This study aimed to evaluate the labelling changes of orphan drugs and to identify postmarketing safety-associated approval ...
Adverse events; Medication safety; Orphan drug designation; Postmarketing surveillance
1.12
143
Medicine; Pharmacology; Genetics
Medicine
2,022
34,983,584
"It's more than milk, it's mental health": a case of online human milk sharing.
International breastfeeding journal
Int Breastfeed J
17
1
10.1186/s13006-021-00445-6
eng
2,022
1
4
2,022
1
4
[BACKGROUND] Milk sharing is not a new concept and occurs today via regulated human milk banks and unregulated online milk sharing groups. Exploring and understanding how, and why, mothers use these peers to peer milk sharing groups, is a vehicle to understanding how breastfeeding mothers can be tangibly supported onli...
Human milk sharing; Online milk sharing; Online social support groups; Online support; Tangible online support
0.99
60
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,022
34,983,563
Circular RNA ciRs-126 promotes hypoxia/reoxygenation cardiac injury possibly through miR-21.
Thrombosis journal
Thromb J
20
1
10.1186/s12959-021-00355-x
eng
2,022
1
4
2,022
1
4
[BACKGROUND] This study aimed to analyze the role of circular RNA ciRs-126 in hypoxia/reoxygenation cardiac injury (H/R). [METHODS] Expression of ciRs-126 and miR-21 in plasma samples from patients with H/R and healthy controls was determined by RT-qPCR. Correlations were analyzed by linear regression. Overexpression o...
Apoptosis; Hypoxia/reoxygenation cardiac injury; ciRs-126; miR-21
0.699
51
Hematology
Medicine
2,022
34,983,538
Drug delivery of 6-bromoindirubin-3'-glycerol-oxime ether employing poly(D,L-lactide-co-glycolide)-based nanoencapsulation techniques with sustainable solvents.
Journal of nanobiotechnology
J Nanobiotechnology
20
1
10.1186/s12951-021-01179-7
eng
2,022
1
4
2,022
1
4
[BACKGROUND] Insufficient solubility and stability of bioactive small molecules as well as poor biocompatibility may cause low bioavailability and are common obstacles in drug development. One example of such problematic molecules is 6-bromoindirubin-3'-glycerol-oxime ether (6BIGOE), a hydrophobic indirubin derivative....
Drug delivery; Indirubin; Inflammation; Nanoparticles; PLGA; Sustainable solvents
1.421
125
Applied Microbiology and Biotechnology; Bioengineering; Biomedical Engineering; Medicine; Molecular Medicine; Nanoscience and Nanotechnology; Pharmaceutical Science
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Engineering; Immunology and Microbiology; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
34,983,428
Similar severity of influenza primary and re-infections in pre-school children requiring outpatient treatment due to febrile acute respiratory illness: prospective, multicentre surveillance study (2013-2015).
BMC infectious diseases
BMC Infect Dis
22
1
10.1186/s12879-021-06988-7
eng
2,022
1
4
2,022
1
4
[BACKGROUND] Influenza virus infections in immunologically naïve children (primary infection) may be more severe than in children with re-infections who are already immunologically primed. We compared frequency and severity of influenza virus primary and re-infections in pre-school children requiring outpatient treatme...
Children; Disease severity; IgG; Immunology; Influenza
1.055
137
Infectious Diseases
Medicine
2,022
34,982,953
The prevalence of refractive error in schoolchildren.
Clinical experimental optometry
Clin Exp Optom
105
8
10.1080/08164622.2021.2003687
eng
2,022
11
null
2,022
1
4
[CLINICAL RELEVANCE] Information on the refractive error prevalence in school-aged children will result in delivering the optimal eye health service to this group. [BACKGROUND] Understanding the prevalence of refractive error in school-aged children is crucial to reduce the consequences of uncorrected refractive error....
Refractive error; anisometropia; astigmatism; hyperopia; myopia; schoolchildren
null
null
null
null
null
34,982,804
Aggressive local treatment for recurrent intrahepatic cholangiocarcinoma-Stereotactic radiofrequency ablation as a valuable addition to hepatic resection.
PloS one
PLoS One
17
1
10.1371/journal.pone.0261136
eng
2,022
null
null
2,022
1
4
[BACKGROUND] To evaluate the efficacy, safety and overall clinical outcome of local treatment for recurrent intrahepatic cholangiocellular carcinoma after hepatic resection. [METHODS] Between 2007 and 2019 72 consecutive patients underwent hepatic resection for primary intrahepatic cholangiocellular carcinoma. If amena...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
34,982,601
Use of Suture-Mediated Closure Devices for Closure of Punctures in Prosthetic Patches or Grafts is Associated With High Rates of Technical Success and Low Complication Rates.
Vascular and endovascular surgery
Vasc Endovascular Surg
56
3
10.1177/15385744211068626
eng
2,022
4
null
2,022
1
4
[OBJECTIVES] Despite the increasing use of endovascular techniques in the management of peripheral vascular disease, there is little data on the safety of percutaneous closure devices in punctures of synthetic vascular material. Our paper sought to address this paucity in the literature by reviewing the incidence of co...
peripheral vascular disease; polytetrafluoroethylene; punctures; vascular closure devices
0.448
56
Surgery; Cardiology and Cardiovascular Medicine; Medicine
Medicine
2,022
34,982,098
Comparison of Drug-Eluting Stent With Bare-Metal Stent in Patients With Symptomatic High-grade Intracranial Atherosclerotic Stenosis: A Randomized Clinical Trial.
JAMA neurology
JAMA Neurol
79
2
10.1001/jamaneurol.2021.4804
eng
2,022
2
1
null
null
null
[IMPORTANCE] In-stent restenosis (ISR) is the primary reason for stroke recurrence after intracranial stenting in patients who were treated with a standard bare-metal stent (BMS). Whether a drug-eluting stent (DES) could reduce the risk of ISR in intracranial atherosclerotic stenosis (ICAS) remains unclear. [OBJECTIVE]...
null
null
null
null
null
null
34,981,754
Classification of maternal thyroid function in early pregnancy using repeated blood samples.
European thyroid journal
Eur Thyroid J
11
2
10.1530/ETJ-21-0055
eng
2,022
2
2
2,022
2
2
[OBJECTIVE] The assessment of maternal thyroid function in early pregnancy is debated. It is well-established that pregnancy-specific reference ranges preferably should be used. We speculated if the use of repeated blood samples drawn in early pregnancy would influence the classification of maternal thyroid function. [...
autoimmunity; hyperthyroidism; hypothyroidism; pregnancy; thyroid function
0.97
32
Endocrinology, Diabetes and Metabolism
Medicine
2,022
34,981,720
Kinetic Characteristics of Neutralizing Antibody Responses Vary among Patients with COVID-19.
Biomedical and environmental sciences : BES
Biomed Environ Sci
34
12
10.3967/bes2021.133
eng
2,021
12
20
null
null
null
[OBJECTIVE] The coronavirus disease 2019 (COVID-19) pandemic continues to present a major challenge to public health. Vaccine development requires an understanding of the kinetics of neutralizing antibody (NAb) responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). [METHODS] In total, 605 serum samp...
Kinetics; Neutralizing antibody; SARS-CoV-2; Sex
null
null
null
null
null
34,981,627
A dinitroaniline herbicide resistance mutation can be nearly lethal to plants.
Pest management science
Pest Manag Sci
78
4
10.1002/ps.6773
eng
2,022
4
null
2,022
1
21
[BACKGROUND] Lolium rigidum is the most important weed in Australian agriculture and pre-emergence dinitroaniline herbicides (e.g., trifluralin) are widely and persistently used for Lolium control. Consequently, evolution of resistance to dinitroaniline herbicides has been increasingly reported. Resistance-endowing tar...
Arg-243-Met; Val-202-Phe; resistance cost; trifluralin
null
null
null
null
null
34,980,974
Risk Stratification of Patients with Stage I Cutaneous Melanoma Using 31-Gene Expression Profiling.
The Journal of clinical and aesthetic dermatology
J Clin Aesthet Dermatol
14
9
null
eng
2,021
9
null
null
null
null
[BACKGROUND] While patients with localized cutaneous melanoma (CM) generally have good five-year melanoma-specific survival rates, identifying patients with localized disease at a high risk of recurrence could allow them access to additional follow-up or surveillance. [OBJECTIVE] We sought to examine the prognostic val...
31-gene expression profile; American Joint Committee on Cancer; cutaneous melanoma; stage I cutaneous melanoma
null
null
null
null
null
34,980,582
Emotion Regulation Mediates Posttraumatic Growth and Cluster B Personality Traits After Childhood Trauma.
Violence and victims
Violence Vict
36
6
10.1891/VV-D-20-00022
eng
2,021
12
1
null
null
null
[OBJECTIVES] Cluster B personality disorder traits and positive psychological change, known as posttraumatic growth (PTG), are both possible outcomes following childhood trauma. However, existing research has not yet explored whether emotion regulation difficulties can simultaneously explain these negative and positive...
childhood trauma; emotion regulation; personality disorder; posttraumatic growth; subjective severity
null
null
null
null
null
34,980,558
Risk factors for subsequent stone events in pediatric nephrolithiasis: A multi-institutional analysis.
Journal of pediatric urology
J Pediatr Urol
18
1
10.1016/j.jpurol.2021.11.012
eng
2,022
2
null
2,021
11
25
[INTRODUCTION] Children with nephrolithiasis have a 50% risk of recurrence 3 years following an index urinary stone event. The American Urological Association guidelines for medical management of nephrolithiasis suggest metabolic evaluations be stratified according to risk of future stone events. However, no such risk ...
Outcomes; Pediatric; Risk factors; Urolithiasis
0.658
63
Pediatrics, Perinatology and Child Health; Urology
Medicine
2,022
34,980,459
CT and MRI features of extraocular muscle granular cell tumour: preliminary experience in eight cases.
Clinical radiology
Clin Radiol
77
4
10.1016/j.crad.2021.12.007
eng
2,022
4
null
2,021
12
31
[AIM] To characterise the computed tomography (CT) and magnetic resonance imaging (MRI) features, in particular the functional MRI characteristics, of extraocular muscle granular cell tumours (GCTs). [MATERIALS AND METHODS] The CT (n=6) and MRI (n=8) features of eight extraocular muscle GCTs cofirmed at histopathology ...
null
0.704
110
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
34,980,163
Repurposing a clinically approved prescription Colquhounia root tablet to treat diabetic kidney disease via suppressing PI3K/AKT/NF-kB activation.
Chinese medicine
Chin Med
17
1
10.1186/s13020-021-00563-7
eng
2,022
1
4
2,022
1
4
[BACKGROUND] Growing clinical evidences show the potentials of Colquhounia root tablet (CRT) in alleviating diabetic kidney disease (DKD). However, its pharmacological properties and underlying mechanisms remain unclear. [METHODS] 'Drug target-Disease gene' interaction network was constructed and the candidate network ...
Colquhounia root tablet; Diabetic kidney disease; Imbalance of immune-inflammation system; Network pharmacology; Tripterygium wilfordii Hook F-based therapeutics
null
null
null
null
null
34,979,947
Association between single nucleotide polymorphism of rs1937 in TFAM gene and longevity among the elderly Chinese population: based on the CLHLS study.
BMC geriatrics
BMC Geriatr
22
1
10.1186/s12877-021-02655-3
eng
2,022
1
3
2,022
1
3
[BACKGROUND] To investigate whether the mitochondrial transcription factor A (TFAM) rs1937 single nucleotide polymorphism (SNP) is associated with longevity. [METHODS] We conducted a case-control study among Chinese long-lived individuals (≥90 years). Data were obtained on 3294 participants who were able to voluntarily...
Long-lived individuals; Longevity; Single nucleotide polymorphism; TFAM; rs1937
1.127
112
Geriatrics and Gerontology
Medicine
2,022
34,979,934
Identification of Pueraria spp. through DNA barcoding and comparative transcriptomics.
BMC plant biology
BMC Plant Biol
22
1
10.1186/s12870-021-03383-x
eng
2,022
1
3
2,022
1
3
[BACKGROUND] Kudzu is a term used generically to describe members of the genus Pueraria. Kudzu roots have been used for centuries in traditional Chinese medicine in view of their high levels of beneficial isoflavones including the unique 8-C-glycoside of daidzein, puerarin. In the US, kudzu is seen as a noxious weed ca...
Comparative transcriptomics; DNA barcoding; Kudzu; Microsatellites
1.159
159
Plant Science
Agricultural and Biological Sciences
2,022
34,979,605
Impact of the COVID-19 Pandemic on HIV Services in Korea: Results from a Cross-Sectional Online Survey.
Infection chemotherapy
Infect Chemother
53
4
10.3947/ic.2021.0112
eng
2,021
12
null
null
null
null
[BACKGROUND] Globally, the coronavirus disease 2019 (COVID-19) pandemic has compromised human immunodeficiency virus (HIV) services. The study aimed to assess the impact of COVID-19 on the access and delivery of HIV care in Korea. [MATERIALS AND METHODS] People living with HIV (PLHIV), people at risk of HIV (PAR) and p...
Anti-retroviral agents; COVID-19; HIV infections; Pre-exposure prophylaxis; SARS-CoV-2
null
null
null
null
null
34,979,333
Oscillometry and Asthma Control in Patients With and Without Fixed Airflow Obstruction.
The journal of allergy and clinical immunology. In practice
J Allergy Clin Immunol Pract
10
5
10.1016/j.jaip.2021.12.026
eng
2,022
5
null
2,022
1
1
[BACKGROUND] Asthma is defined by the presence of reversible airflow limitation, yet persistently abnormal spirometry may develop despite appropriate asthma treatment. Fixed airflow obstruction (FAO) describes abnormal postbronchodilator spirometry that is associated with greater symptom burden and disease severity. Re...
Asthma control; Fixed airflow obstruction; Forced oscillation technique; Oscillometry; Symptoms
null
null
null
null
null
34,979,219
Disparities in Telemedicine Utilization for Urology Patients During the COVID-19 Pandemic.
Urology
Urology
163
null
10.1016/j.urology.2021.11.037
eng
2,022
5
null
2,022
1
1
[OBJECTIVE] To determine the odds of accessing telemedicine either by phone or by video during the COVID-19 pandemic. [METHODS] We performed a retrospective study of patients who were seen at a single academic institution for a urologic condition between March 15, 2020 and September 30, 2020. The primary outcome was to...
null
0.686
197
Urology
Medicine
2,022
34,979,186
Risk factors associated with postpartum depressive symptoms: A multinational study.
Journal of affective disorders
J Affect Disord
301
null
10.1016/j.jad.2021.12.121
eng
2,022
3
15
2,021
12
31
[OBJECTIVE] To evaluate the association between maternal age, parity, gestational number (singleton vs twin), newborn gender and self-reported postpartum depressive symptoms (PDS) in a large multinational sample using survey data from a digital telephone application. [METHODS] Women using the Flo app answered a survey ...
Gestational number; Infant sex; Maternal age; Parity; Postpartum depression
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
34,979,066
Related Fluoxetine and Methylprednisolone Changes of TNF-α and IL-6 Expression in The Hypothyroidism Rat Model of Spinal Cord Injury.
Cell journal
Cell J
23
7
10.22074/cellj.2021.7459
eng
2,021
12
null
2,021
12
29
[OBJECTIVE] Spinal cord injury (SCI) is a serious clinical condition that leads to disability. Following primary injury, proinflammatory cytokines play an important role in the subsequent secondary events. The thyroid hormone (TH) is known as the modulator of inflammatory cytokines and acts as a neuroprotective agent. ...
Fluoxetine; Interleukin-6; Methylprednisolone; Spinal Cord Injury; Tumor Necrosis Factor-Alpha
0.563
43
Cell Biology; Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,021
34,978,744
Are national treatment guidelines for falciparum malaria in line with WHO recommendations and is antimalarial resistance taken into consideration? - A review of guidelines in non-endemic countries.
Tropical medicine international health : TM IH
Trop Med Int Health
27
2
10.1111/tmi.13715
eng
2,022
2
null
2,022
1
13
[OBJECTIVE] Plasmodium falciparum infections are a relatively rare but potentially deadly disease found in returning travellers. We compare the national treatment guidelines of non-endemic countries with the WHO guidelines for the treatment of Plasmodium falciparum infections. [METHODS] Review. We identified non-endemi...
WHO; guidelines; malaria; review; treatment
null
null
null
null
null
34,978,663
Changes in the Expression of Long Non-Coding RNA SDMGC and Its Target Gene, TRIM16, in Patients with Gastric Cancer.
Journal of gastrointestinal cancer
J Gastrointest Cancer
54
1
10.1007/s12029-021-00791-y
eng
2,023
3
null
2,022
1
3
[PURPOSE] Gastric cancer (GC) has been identified worldwide as one of the most common cancer types with a high mortality rate. LncRNA SDMGC has been recognized as an oncogene with regulatory effects on its target gene, TRIM16, which is believed to play a tumor-suppressing role in various cancers. Both these genes are i...
Gastric cancer; Oncogene; SDMGC; TRIM16; Tumor suppressor gene; lncRNA
0.438
54
Gastroenterology; Oncology
Medicine
2,023
35,034,188
Prosthetic voice rehabilitation after laryngoesophagectomy: surgical and functional outcomes.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Eur Arch Otorhinolaryngol
279
8
10.1007/s00405-022-07251-8
eng
2,022
8
null
2,022
1
16
[PURPOSE] Quality of Life (QoL) after extensive head and neck resections is of paramount importance, especially after pharyngolaryngectomy or pharyngolaryngoesophagectomy where complex digestive tract reconstruction is required (with gastric pull-up or colon transposition). Tracheodigestive puncture (TDP) is the only v...
Pharyngolaryngoesophagectomy; Speech restoration; Voice prosthesis
0.857
94
Otorhinolaryngology; Medicine
Medicine
2,022
35,034,167
Prostatic metaplasia of the vagina in transmasculine individuals.
World journal of urology
World J Urol
40
3
10.1007/s00345-021-03907-y
eng
2,022
3
null
2,022
1
16
[PURPOSE] To determine the prevalence of prostatic metaplasia in an expanded cohort of transmasculine individuals undergoing gender-affirming resection of vaginal tissue. [METHODS] Institutional Review Board approval was obtained. Clinical records were reviewed for all transmasculine individuals undergoing vaginal tiss...
Androgens; Metaplasia; Pathology; Transgender persons
1.014
104
Urology
Medicine
2,022
35,034,014
Hippocampal Subfield Volumes and Cognitive Function in Schizophrenia and Mood Disorders.
Neuropsychobiology
Neuropsychobiology
81
3
10.1159/000521102
eng
2,022
null
null
2,022
1
14
[INTRODUCTION] The hippocampus is relevant to cognitive function in schizophrenia (SCZ) and mood disorder patients. Although not anatomically uniform, it is clearly divided into subfields. This study aimed to elucidate the relationship between hippocampal subfield volume and cognitive function in patients with SCZ, bip...
Bipolar disorder; Cognition; Hippocampal subfields; Major depressive disorder; Schizophrenia
0.761
95
Neuropsychology and Physiological Psychology; Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience; Psychology
2,022
35,033,869
The orphan receptor GPRC5B activates pro-inflammatory signaling in the vascular wall via Fyn and NFκB.
Biochemical and biophysical research communications
Biochem Biophys Res Commun
592
null
10.1016/j.bbrc.2022.01.009
eng
2,022
2
12
2,022
1
7
[BACKGROUND AND AIMS] Atherosclerosis is driven by an inflammatory process of the vascular wall. The novel orphan G-protein coupled receptor 5B of family C (GPRC5B) is involved in drosophila sugar and lipid metabolism as well as mice adipose tissue inflammation. Here, we investigated the role of GPRC5B in the pro-ather...
Atherosclerosis; GPCR; GPRC5B; Hyperglycemia; Vascular inflammation
0.791
298
Biophysics; Biochemistry; Cell Biology; Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,022
35,033,411
Predictors of changes in preoperative tumor stage between dynamic computed tomography and gadoxetate disodium-enhanced magnetic resonance imaging for hepatocellular carcinoma.
Journal of the Formosan Medical Association = Taiwan yi zhi
J Formos Med Assoc
121
8
10.1016/j.jfma.2021.12.026
eng
2,022
8
null
2,022
1
13
[BACKGROUND/PURPOSE] Gadoxetate disodium-enhanced magnetic resonance imaging (EOB-MRI) has a higher diagnostic accuracy for hepatocellular carcinoma (HCC) than computed tomography (CT). However, indications for performing EOB-MRI after dynamic CT are not well defined. Therefore, we investigated the clinical factors ass...
Computed tomography; Gadoxetic acid; Hepatocellular carcinoma; Magnetic resonance imaging; Neoplasm staging
null
null
null
null
null
35,033,170
Sedentary lifestyle and body composition in type 2 diabetes.
Diabetology & metabolic syndrome
Diabetol Metab Syndr
14
1
10.1186/s13098-021-00778-6
eng
2,022
1
15
2,022
1
15
[BACKGROUND] Body composition alterations may participate in the pathophysiological processes of type 2 diabetes (T2D). A sedentary lifestyle may be responsible for alterations of body composition and adverse consequences, but on which body composition of patients with T2D and to what extent the sedentary lifestyle has...
Bone mineral density; Fat distribution; Sedentary lifestyle; Skeletal muscle mass
null
null
null
null
null
35,033,109
Conceptualizing and implementing a health workforce registry in Nigeria.
Human resources for health
Hum Resour Health
20
1
10.1186/s12960-022-00706-3
eng
2,022
1
15
2,022
1
15
[BACKGROUND] Nigeria's health sector aims to ensure that the right number of health workers that are qualified, skilled, and distributed equitably, are available for quality health service provision at all levels. Achieving this requires accurate and timely health workforce information. This informed the development of...
HRH evidence; HRH information system; Health workforce registry; Nigeria Health Workforce Registry
1.203
89
Public Administration; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,022
35,033,082
Molecular identification and anti-malarial drug resistance profile of Plasmodium falciparum from patients attending Kisoro Hospital, southwestern Uganda.
Malaria journal
Malar J
21
1
10.1186/s12936-021-04023-3
eng
2,022
1
15
2,022
1
15
[BACKGROUND] The evolution of malaria infection has necessitated the development of highly sensitive diagnostic assays, as well as the use of dried blood spots (DBS) as a potential source of deoxyribonucleic acid (DNA) yield for polymerase chain reaction (PCR) assays. This study identified the different Plasmodium spec...
Dried blood spots; High-resolution melting analysis; Plasmodium species
1.237
126
Infectious Diseases; Parasitology
Immunology and Microbiology; Medicine
2,022
35,033,061
Relationship between gut microbiota and lung function decline in patients with chronic obstructive pulmonary disease: a 1-year follow-up study.
Respiratory research
Respir Res
23
1
10.1186/s12931-022-01928-8
eng
2,022
1
15
2,022
1
15
[OBJECTIVE] Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease characterized by a persistent limitation in airflow. Gut microbiota is closely correlated with lung inflammation. However, gut microbiota has not been studied in patients with declining lung function, due to chronic lung dis...
Chronic obstructive pulmonary disease; Gut microbiota; Lung function decline; Next generation sequencing; Stool sample
1.753
134
Pulmonary and Respiratory Medicine
Medicine
2,022
35,032,880
Neutrophil-to-lymphocyte ratio and monocyte-to-lymphocyte ratio are associated with a 2-year relapse in patients with multiple sclerosis.
Multiple sclerosis and related disorders
Mult Scler Relat Disord
58
null
10.1016/j.msard.2022.103514
eng
2,022
2
null
2,022
1
10
[BACKGROUND] The association between increased neutrophil-to-lymphocyte ratio (NLR) and multiple sclerosis has been demonstrated in several studies. The monocyte-to-lymphocyte ratio (MLR) is an emerging biomarker for disease monitoring. Moreover, there has not been a published Taiwanese study to date. [AIM] To investig...
Monocyte-to-lymphocyte ratio; Multiple sclerosis; Neutrophil-to-lymphocyte ratio; Outcome; Relapse
0.92
70
Medicine; Neurology; Neurology
Medicine; Neuroscience
2,022
35,032,722
Bone suppression on pediatric chest radiographs via a deep learning-based cascade model.
Computer methods and programs in biomedicine
Comput Methods Programs Biomed
215
null
10.1016/j.cmpb.2022.106627
eng
2,022
3
null
2,022
1
10
[BACKGROUND AND OBJECTIVE] Bone suppression images (BSIs) of chest radiographs (CXRs) have been proven to improve diagnosis of pulmonary diseases. To acquire BSIs, dual-energy subtraction (DES) or a deep-learning-based model trained with DES-based BSIs have been used. However, neither technique could be applied to pedi...
Bone suppression; Chest radiograph; Deep learning; Image translation; Pediatric
1.118
150
Computer Science Applications; Health Informatics; Software
Computer Science; Medicine
2,022
35,032,694
Elevated Basal Serum Tryptase: Disease Distribution and Variability in a Regional Health System.
The journal of allergy and clinical immunology. In practice
J Allergy Clin Immunol Pract
10
9
10.1016/j.jaip.2021.12.031
eng
2,022
9
null
2,022
1
12
[BACKGROUND] Hereditary-alpha tryptasemia (HαT) is the most common etiology for elevated basal serum tryptase (BST). However, the utility of tryptase genotyping of individuals with elevated BST in general clinical practice remains undefined. Moreover, studies showing associations between elevated BST and chronic kidney...
Biomarkers; Chronic kidney disease; Disease distribution; Elevated basal tryptase algorithm; Hereditary-alpha tryptasemia; Mastocytosis; Myeloid neoplasms; Tryptase; Variability
null
null
null
null
null
35,032,351
Lung transplantation in the septuagenarian can be successfully performed though long-term results impacted by diseases of aging.
Clinical transplantation
Clin Transplant
36
5
10.1111/ctr.14593
eng
2,022
5
null
2,022
1
27
[BACKGROUND] Advanced age is considered a risk factor for lung transplantation (LTX). We sought to evaluate the long-term outcomes of LTX in the septuagenarian. [METHODS] LTX recipients in the UNOS transplant registry (May 1, 2005-June 12, 2020) were stratified into 18-59, 60-69, and > = 70 years of age. Recipient and ...
chronic lung diseases; lung transplantation; septuagenarian
0.842
90
Transplantation
Medicine
2,022
35,032,217
Estrogen concentration and estrogen receptor-β expression in postmenopausal colon cancer considering patient/tumor background.
Journal of cancer research and clinical oncology
J Cancer Res Clin Oncol
148
5
10.1007/s00432-021-03889-9
eng
2,022
5
null
2,022
1
15
[PURPOSE] A large number of studies have suggested an inhibitory role of estrogens against colorectal cancer (CRC), but persistent controversy exists. CRC characteristics are affected by sex, age, and tumor locus, suggesting the need for a systematic study considering these factors. The purpose of this study was to ver...
Age; Colon cancer; Estrogen; Postmenopausal women
1.017
114
Medicine; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,032,209
Establishment of childhood hepatoblastoma xenografts and evaluation of the anti-tumour effects of anlotinib, oxaliplatin and sorafenib.
Pediatric surgery international
Pediatr Surg Int
38
3
10.1007/s00383-021-05043-5
eng
2,022
3
null
2,022
1
15
[BACKGROUND] Hepatoblastoma (HB) is a common primary malignant liver tumour in children, mainly treated by means of traditional chemotherapy using platinum and doxorubicin (ADM). There has been limited progress in the research and development of new drugs for treating HB. [METHODS] A tumour biopsy from a child with HB ...
Anlotinib; Childhood hepatoblastoma (HB); Oxaliplatin; Patient-derived xenograft (PDX); Sorafenib
0.575
78
Medicine; Pediatrics, Perinatology and Child Health; Surgery
Medicine
2,022
35,031,518
Protein Kinase CK2 Acts as a Molecular Brake to Control NADPH Oxidase 1 Activation and Colon Inflammation.
Cellular and molecular gastroenterology and hepatology
Cell Mol Gastroenterol Hepatol
13
4
10.1016/j.jcmgh.2022.01.003
eng
2,022
null
null
2,022
1
12
[BACKGROUND AND AIMS] NADPH oxidase 1 (NOX1) has emerged as a prime regulator of intestinal mucosa immunity and homeostasis. Dysregulation of NOX1 may cause inflammatory bowel disease (IBD). It is not clear how NOX1 is regulated in vivo under inflammatory conditions. We studied the role of CK2 in this process. [METHODS...
CK2; IBD; NOX1; ROS
2.454
75
Gastroenterology; Hepatology
Medicine
2,022
35,031,496
Platelet-rich plasma vs. corticosteroid injections for the treatment of recalcitrant lateral epicondylitis: a cost-effectiveness Markov decision analysis.
Journal of shoulder and elbow surgery
J Shoulder Elbow Surg
31
5
10.1016/j.jse.2021.12.010
eng
2,022
5
null
2,022
1
11
[BACKGROUND] Both platelet-rich plasma (PRP) and corticosteroid injections may be used to treat lateral epicondylitis. We evaluated the cost-effectiveness of PRP injections vs. corticosteroid injections for the treatment of recalcitrant lateral epicondylitis. [METHODS] Markov modeling was used to analyze the base-case ...
Adrenal cortex hormones; arm; cost-benefit analysis; health care costs; platelet-rich plasma; quality of life; quality-adjusted life-years; tennis elbow
1.666
178
Medicine; Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,022
35,031,269
Clinician perspectives on the need for training on caring for pregnant women with intellectual and developmental disabilities.
Disability and health journal
Disabil Health J
15
2
10.1016/j.dhjo.2021.101262
eng
2,022
4
null
2,021
12
17
[BACKGROUND] Women with intellectual and developmental disabilities (IDDs) experience disparities in obstetric care access and quality, in addition to communication gaps with healthcare providers. Many obstetric providers are untrained and uneducated about critical aspects of providing care to persons with IDDs. [OBJEC...
Graduate medical education; Intellectual disability; Medical education; Obstetrics; Pregnancy; Training
1.635
60
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,022
35,031,227
Combination of Atezolizumab and Obinutuzumab in Patients with Relapsed/Refractory Follicular Lymphoma and Diffuse Large B-Cell Lymphoma: Results from a Phase 1b Study.
Clinical lymphoma, myeloma & leukemia
Clin Lymphoma Myeloma Leuk
22
7
10.1016/j.clml.2021.12.010
eng
2,022
7
null
2,021
12
24
[BACKGROUND] This was an open-label, phase 1b study assessing the safety, tolerability, preliminary efficacy and pharmacokinetics of the combination of atezolizumab and obinutuzumab in patients with relapsed/refractory follicular lymphoma (FL) or diffuse large B-cell lymphoma (DLBCL). There is a mechanistic rationale s...
Atezolizumab; Diffuse large B-cell lymphoma; Follicular lymphoma; Obinutuzumab
null
null
null
null
null
35,031,052
Patients' perspective on supposedly patient-relevant process and outcome parameters: a cross-sectional survey within the 'PRO patients study'.
BMC health services research
BMC Health Serv Res
22
1
10.1186/s12913-021-07437-6
eng
2,022
1
14
2,022
1
14
[BACKGROUND] To be able to make informed choices based on their individual preferences, patients need to be adequately informed about treatment options and their potential outcomes. This implies that studies measure the effects of care based on parameters that are relevant to patients. In a previous scoping review, we ...
Patient involvement; Patient preference; Patient relevance; Patient-centered care; Patient-relevant outcome
0.964
157
Health Policy
Medicine
2,022
35,031,049
Evaluation of a Medicaid performance improvement project to reduce high-dose opioid prescriptions.
BMC health services research
BMC Health Serv Res
22
1
10.1186/s12913-022-07477-6
eng
2,022
1
14
2,022
1
14
[BACKGROUND] In 2015, Oregon's Medicaid program implemented a performance improvement project to reduce high-dose opioid prescribing across its 16 coordinated care organizations (CCOs). The objective of this study was to evaluate the effect of that program on prescription opioid use and outcomes. [METHODS] Using Medica...
Medicaid; Opioids; Overdose
0.964
157
Health Policy
Medicine
2,022
35,031,044
The mediating role of motivated strategies in the relationship between formative classroom assessment and academic well-being in medical students: a path analysis.
BMC medical education
BMC Med Educ
22
1
10.1186/s12909-022-03118-y
eng
2,022
1
14
2,022
1
14
[BACKGROUND] The support of students' academic well-being is one of the main agendas of medical education. For medical students, well-being can help prevent burnout and provides students with grounds for their future healthcare setting. The aim of this study was to examine the mediating role of motivated strategies for...
Academic well-being; Formative assessment; Medical students; Motivated strategies for learning
0.914
107
Education; Medicine
Medicine; Social Sciences
2,022
35,031,000
Prevalence of risk behaviors and correlates of SARS-CoV-2 positivity among in-school contacts of confirmed cases in a Georgia school district in the pre-vaccine era, December 2020-January 2021.
BMC public health
BMC Public Health
22
1
10.1186/s12889-021-12347-7
eng
2,022
1
14
2,022
1
14
[BACKGROUND] There is a continuing risk for COVID-19 transmission in school settings while transmission is ongoing in the community, particularly among unvaccinated populations. To ensure that schools continue to operate safely and to inform implementation of prevention strategies, it is imperative to gain better under...
Behavioral epidemiology; Behaviors; COVID-19; Children; SARS-CoV-2; Schools; Students
1.307
211
Public Health, Environmental and Occupational Health
Medicine
2,022
35,030,538
Efficacy of high flow nasal oxygenation against hypoxemia in sedated patients receiving gastrointestinal endoscopic procedures: A systematic review and meta-analysis.
Journal of clinical anesthesia
J Clin Anesth
77
null
10.1016/j.jclinane.2022.110651
eng
2,022
5
null
2,022
1
12
[STUDY OBJECTIVE] To evaluate the impact of high flow nasal oxygenation (HFNO) on the risk of hypoxemia during gastrointestinal endoscopic procedures (GEPs) under sedation. [DESIGN] Meta-analysis of randomized controlled trials. [SETTING] Gastrointestinal endoscopy. [INTERVENTION] HFNO. [PATIENTS] Adults patients under...
Gastrointestinal endoscopic procedures; High-flow nasal cannula; Hypoxemia; Propofol; Sedation
1.019
86
Anesthesiology and Pain Medicine
Medicine
2,022
35,029,530
The Effectiveness of Serious Games for Alleviating Depression: Systematic Review and Meta-analysis.
JMIR serious games
JMIR Serious Games
10
1
10.2196/32331
eng
2,022
1
14
2,022
1
14
[BACKGROUND] Depression is a common mental disorder characterized by disturbances in mood, thoughts, or behaviors. Serious games, which are games that have a purpose other than entertainment, have been used as a nonpharmacological therapeutic intervention for depression. Previous systematic reviews have summarized evid...
cognitive behavioral therapy; depression; exergames; meta-analysis; serious games; systematic reviews
0.78
45
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Biomedical Engineering; Psychiatry and Mental Health
Engineering; Health Professions; Medicine
2,022
35,029,231
Theta burst stimulation versus high-frequency repetitive transcranial magnetic stimulation for poststroke dysphagia: A randomized, double-blind, controlled trial.
Medicine
Medicine (Baltimore)
101
2
10.1097/MD.0000000000028576
eng
2,022
1
14
null
null
null
[BACKGROUND] Repetitive transcranial magnetic stimulation (rTMS) of high-frequency (10 Hz) on suprahyoid motor cortex has been an evidence-based treatment for poststroke dysphagia. Intermittent theta burst stimulation (iTBS) can be performed in 3 minutes compared with 20 ± 5 minutes for 10 Hz rTMS. This study aimed to ...
null
null
null
null
null
null
35,028,979
Comparison between peritoneal dialysis and hemodialysis on kidney function recovery in incident kidney failure: A nationwide cohort study.
Seminars in dialysis
Semin Dial
35
3
10.1111/sdi.13050
eng
2,022
5
null
2,022
1
13
[BACKGROUND] Patients with kidney failure who start dialysis have a chance of kidney function recovery. Whether the initial dialysis modality affects the possibility of recovery is not fully understood. [METHODS] We included patients diagnosed with kidney failure requiring dialysis during 2001-2013 from the Taiwan Nati...
null
0.555
93
Nephrology
Medicine
2,022
35,028,930
RENORT: a project to analyze patterns of care in radiation oncology in Spain.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Clin Transl Oncol
24
7
10.1007/s12094-021-02772-w
eng
2,022
7
null
2,022
1
13
[PURPOSE] RENORT is an application (app) developed to assess the role of radiotherapy in the treatment of cancer using the oncology information systems (OIS). [METHODS/PATIENTS] The RENORT app was used to analyze the data for all patients seen and/or treated at six radiation oncology departments in Spain in 2019. This ...
Cancer; OIS; Pattern of care; RENORT; Radiotherapy
null
null
null
null
null
35,028,482
Trichophyton species isolated from asymptomatic patients of the pet-owner pair in Mexico.
Current medical mycology
Curr Med Mycol
7
2
10.18502/cmm.7.2.7029
eng
2,021
6
null
null
null
null
[BACKGROUND AND PURPOSE] Superficial mycoses are the fourth most common cause of disease worldwide. It is not surprising that zoonotic transmission occurs to humans due to close contact with different animals, be it companion or farm animals. Therefore, the objective of this study was to determine the presence of asymp...
Mycoses; Pet; Pet owners
null
null
null
null
null
35,028,055
Orthodontic force regulates metalloproteinase-3 promoter in osteoblasts and transgenic mouse models.
Journal of dental sciences
J Dent Sci
17
1
10.1016/j.jds.2021.11.015
eng
2,022
1
null
2,021
12
4
[BACKGROUND/PURPOSE] Previously we demonstrated up-regulation of matrix metalloproteinase-3 (MMP-3) in human osteoblasts under compression and in bony specimens of experimental orthodontic tooth movement (OTM). Here, we studied the temporal characteristics of compression stimulation in human and mouse osteoblast cell l...
Matrix metalloproteinase-3; Mechanical force; Orthodontic tooth movement; Transgenic mouse
0.667
36
Dentistry
Dentistry
2,022
35,028,021
Comparison of marginal and internal fit of 5-unit zirconia fixed dental prostheses fabricated with CAD/CAM technology using direct and indirect digital scans.
Journal of dental sciences
J Dent Sci
17
1
10.1016/j.jds.2021.07.012
eng
2,022
1
null
2,021
7
30
[BACKGROUND/PURPOSE] Advancements in digital dentistry and the development of intraoral scanners (IOS) have provided clinicians with an accurate and efficient alternative to analog impressions. The aim of this study was to assess the accuracy of the marginal and internal fit of 5-unit monolithic zirconia fixed dental p...
Digital dentistry; Digital impression; Internal fit; Intraoral scans; Zirconia
0.667
36
Dentistry
Dentistry
2,022
35,027,405
Tofacitinib and risk of cardiovascular outcomes: results from the Safety of TofAcitinib in Routine care patients with Rheumatoid Arthritis (STAR-RA) study.
Annals of the rheumatic diseases
Ann Rheum Dis
81
6
10.1136/annrheumdis-2021-221915
eng
2,022
6
null
2,022
1
13
[OBJECTIVES] Recent results from 'ORAL Surveillance' trial have raised concerns regarding the cardiovascular safety of tofacitinib in patients with rheumatoid arthritis (RA). We further examined this safety concern in the real-world setting. [METHODS] We created two cohorts of patients with RA initiating treatment with...
antirheumatic agents; arthritis; epidemiology; rheumatoid; rheumatoid arthritis
6.489
300
Biochemistry, Genetics and Molecular Biology; Immunology; Immunology and Allergy; Rheumatology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,022
35,027,338
Long-Term Clinical Outcomes and Sequelae of Therapy in Early-Stage Orbital Mucosa-Associated Lymphoid Tissue Lymphoma.
Clinical lymphoma, myeloma & leukemia
Clin Lymphoma Myeloma Leuk
22
7
10.1016/j.clml.2021.12.013
eng
2,022
7
null
2,021
12
25
[INTRODUCTION] Orbital mucosa-associated lymphoid tissue (MALT) lymphoma, which are rare and indolent, often present at an early stage. We report the efficacy and safety outcomes of treatment in these patients. [METHODS] We analyzed adult patients with stage IE or IIE orbital MALT lymphoma between 1999 and 2017 treated...
Clinical outcome; Late sequelae; MALT; Orbital lymphoma; Radiotherapy
null
null
null
null
null
35,027,219
Response capability of hospitals to an incident caused by mass gatherings in southeast Iran.
Injury
Injury
53
5
10.1016/j.injury.2021.12.055
eng
2,022
5
null
2,022
1
6
[BACKGROUND AND OBJECTIVES] Hospitals are expected to provide a safe environment for patients, visitors, and employees during emergencies and disasters, as well as provide health care to disaster survivors. The aim of this study was to evaluate the response capability of hospitals to an incident caused by mass gatherin...
Capability; Hospital; Incident; Mass gathering; Response
0.698
151
Surgery; Emergency Medicine; Orthopedics and Sports Medicine
Medicine
2,022
35,027,142
Long-term experience and Visual Acuity outcomes in Peters Anomaly cases.
Archivos de la Sociedad Espanola de Oftalmologia
Arch Soc Esp Oftalmol (Engl Ed)
97
1
10.1016/j.oftale.2021.01.008
eng
2,022
1
null
2,021
11
21
[PURPOSE] To report the results in a series of Peters Anomaly cases, and propose management and treatment approaches according to the alterations associated with each case. [MATERIAL AND METHODS] A retrospective analysis was performed on the records of 27 patients (32 eyes) clinically diagnosed with Peters Anomaly. Eac...
Congenital corneal opacity; Penetrating keratoplasty procedure; Peripheral iridectomy; Peters anomaly; Queratoplastia penetrante
0.218
27
Ophthalmology
Medicine
2,022
35,027,028
Serum rheumatoid factor IgA, anti-citrullinated peptide antibodies with secretory components, and anti-carbamylated protein antibodies associate with interstitial lung disease in rheumatoid arthritis.
BMC musculoskeletal disorders
BMC Musculoskelet Disord
23
1
10.1186/s12891-021-04985-0
eng
2,022
1
13
2,022
1
13
[OBJECTIVE] Rheumatoid arthritis (RA) is often complicated with chronic lung diseases (CLD), including interstitial lung disease (ILD) and airway disease, which occur as extra-articular manifestations. CLD in RA have been associated with the production of rheumatoid factor (RF), anti-citrullinated peptide antibody (ACP...
Anti-citrullinated peptide antibody; IgA; Interstitial lung disease; Nonspecific interstitial pneumonia; Rheumatoid arthritis; Rheumatoid factor; Secretory component; Usual interstitial pneumonia
0.716
131
Orthopedics and Sports Medicine; Rheumatology
Medicine
2,022
35,027,001
Inflammation-scores as prognostic markers of overall survival in lung cancer: a register-based study of 6,210 Danish lung cancer patients.
BMC cancer
BMC Cancer
22
1
10.1186/s12885-021-09108-5
eng
2,022
1
14
2,022
1
14
[BACKGROUND] Inflammation-scores based on general inflammation markers are suggested as prognostic markers of overall survival (OS) in lung cancer. However, whether these inflammation-scores improves the prognostication performed by well-established prognostic markers is unsettled. In a large register-based lung cancer...
Aarhus Composite Biomarker Score (ACBS); Combined NLR and GPS (CNG); Inflammation-score; Lung cancer; Modified Glasgow Prognostic Score (mGPS); Neutrocyte-lymphocyte-raio (NLR)
1.137
171
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,026,963
MicroRNA Expression in Neonates with Late-onset Sepsis - A Cross-sectional Comparative Study.
Immunological investigations
Immunol Invest
51
6
10.1080/08820139.2021.2020282
eng
2,022
8
null
2,022
1
14
[BACKGROUND] Neonatal sepsis is a major health concern among neonates with higher morbidity and mortality rate. Studies have recently speculated the importance of differential expression of circulating mature micro-RNAs (miRNAs) which could serve as diagnostic as well as prognostic markers for risk of mortality in neon...
Biomarker; Neonatal sepsis; late-onset neonatal sepsis; micro RNA
0.596
56
Medicine; Immunology
Immunology and Microbiology; Medicine
2,022
35,026,961
Ratio of Mixed Venous Oxygen Saturation-to-Pulmonary Capillary Wedge Pressure: Insights From the Veterans Affairs Clinical Assessment, Reporting, and Tracking Program.
Circulation. Heart failure
Circ Heart Fail
15
2
10.1161/CIRCHEARTFAILURE.121.008838
eng
2,022
2
null
2,022
1
14
[BACKGROUND] Hemodynamic values from right heart catheterization aid diagnosis and clinical decision-making but may not predict outcomes. Mixed venous oxygen saturation percentage and pulmonary capillary wedge pressure relate to cardiac output and congestion, respectively. We theorized that a novel, simple ratio of the...
cardiac catheterization; diagnosis; heart failure; hemodynamics; outcome assessment
null
null
null
null
null
35,026,491
Efficacy and utilization of smartphone applications for smoking cessation among low-income adults: Secondary analysis of the iCanQuit randomized trial.
Drug and alcohol dependence
Drug Alcohol Depend
231
null
10.1016/j.drugalcdep.2021.109258
eng
2,022
2
1
2,021
12
31
[INTRODUCTION] Evidence of digital interventions that are efficacious among low-income populations is scarce. In a secondary analysis, we determined the efficacy and utilization of an Acceptance and Commitment Therapy (ACT)-based smartphone application (iCanQuit) versus a U.S. Clinical Practice Guidelines (USCPG)-based...
Acceptance & Commitment Therapy; QuitGuide; Smartphone applications; iCanQuitLow-income; smoking cessation
1.562
193
Pharmacology; Pharmacology; Psychiatry and Mental Health; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,026,061
Allelic dropout in PAH affecting the results of genetic diagnosis in phenylketonuria.
Journal of pediatric endocrinology & metabolism : JPEM
J Pediatr Endocrinol Metab
35
3
10.1515/jpem-2021-0336
eng
2,022
3
28
2,022
1
14
[OBJECTIVES] Phenylketonuria (PKU) is an inherited autosomal recessive disorder of phenylalanine metabolism. It is mainly caused by a deficiency in phenylalanine hydroxylase (PAH) and frequently diagnosed with Sanger sequencing. To some extent, allelic dropout can explain the inconsistency in genotype and phenotype. [M...
allelic dropout; phenylketonuria (PKU); variant
null
null
null
null
null
35,025,034
Phylogenetic relationship and genetic diversity of Turkish peanut viruses.
Molecular biology reports
Mol Biol Rep
49
3
10.1007/s11033-022-07137-2
eng
2,022
3
null
2,022
1
13
[BACKGROUND] Viral diseases of peanuts (Arachis hypogaea) have never been reported in Turkey. Analyzing genetic diversity using phylogenetic analysis is important to understanding disease complexes. [METHODS AND RESULTS] Samples were taken from 63 plants showing virus-like symptoms from two major cultivation regions in...
PStV; PeMoV; Phylogenetic; Similarity; TuYV
0.578
96
Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,024,923
Modified Frailty Index to Assess Risk in Elderly Patients Undergoing Distal Pancreatectomy: A Retrospective Single-Center Study.
World journal of surgery
World J Surg
46
4
10.1007/s00268-021-06436-2
eng
2,022
4
null
2,022
1
13
[BACKGROUND] To compare the postoperative course of elderly patients (≥70 years) submitted to minimally invasive (MIDP) versus open distal pancreatectomy (ODP) and to evaluate if the modified Frailty Index (mFI) predicts the surgical course of elderly patients submitted to DP. [METHODS] Data of patients aged ≥70 who un...
null
0.902
176
Surgery
Medicine
2,022
35,024,838
Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections: A Randomized Clinical Trial.
JAMA network open
JAMA Netw Open
5
1
10.1001/jamanetworkopen.2021.37277
eng
2,022
1
4
2,022
1
4
[IMPORTANCE] The consumption of broad-spectrum drugs has increased as a consequence of the spread of multidrug-resistant (MDR) Escherichia coli. Finding alternatives for these infections is critical, for which some neglected drugs may be an option. [OBJECTIVE] To determine whether fosfomycin is noninferior to ceftriaxo...
null
4.108
154
Medicine
Medicine
2,022
35,024,785
Corneal Confocal Microscopy in Type 1 Diabetes Mellitus: A Six-Year Longitudinal Study.
Translational vision science & technology
Transl Vis Sci Technol
11
1
10.1167/tvst.11.1.17
eng
2,022
1
3
null
null
null
[PURPOSE] The current study describes corneal nerve morphology using in vivo confocal microscopy (IVCM) in patients with type 1 diabetes (T1D) who were followed up for 6 years, and it examines the relationship between corneal parameters and metabolic control of glucose and peripheral neuropathy. [METHODS] Sixty-two par...
null
null
null
null
null
null
35,024,740
Morphometric study for determining the anteroposterior position of the mental foramen in dentate human subjects.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Rom J Morphol Embryol
62
2
10.47162/RJME.62.2.18
eng
2,021
null
null
null
null
null
[BACKGROUND] The mental foramen (MnF) is the place where the mental nerve and mental artery exit the body of the mandible, being an important landmark for dentoalveolar surgery. [MATERIALS AND METHODS] For the assessment of MnF topography, we performed a direct morphometric study and two morphometric imaging studies th...
null
null
null
null
null
null
35,024,462
Imaging response assessment for predicting outcomes after bioselection chemotherapy in larynx cancer: A secondary analysis of two prospective trials.
Clinical and translational radiation oncology
Clin Transl Radiat Oncol
33
null
10.1016/j.ctro.2021.12.006
eng
2,022
3
null
2,021
12
23
[BACKGROUND AND PURPOSE] Bioselection with induction chemotherapy in larynx cancer is associated with excellent larynx preservation and disease-specific survival but requires visual inspection of the primary tumor. We retrospectively compare clinical and imaging response in bioselected patients to develop predictive mo...
Bioselection imaging; Chemoradiation; Laryngectomy; Locally advanced laryngeal cancer
1.104
37
Radiology, Nuclear Medicine and Imaging; Oncology
Medicine
2,022
35,024,139
Identification of polo-like kinase 1 as a therapeutic target in murine lupus.
Clinical & translational immunology
Clin Transl Immunology
11
1
10.1002/cti2.1362
eng
2,022
null
null
2,022
1
6
[INTRODUCTION] The signalling cascades that contribute to lupus pathogenesis are incompletely understood. We address this by using an unbiased activity-based kinome screen of murine lupus. [METHODS] An unbiased activity-based kinome screen (ABKS) of 196 kinases was applied to two genetically different murine lupus stra...
PLK1; SLE; drug target; kinase activity
null
null
null
null
null
35,023,953
TPMT mRNA Expression: A Novel Prognostic Biomarker for Patients with Colon Cancer by Bioinformatics Analysis.
International journal of general medicine
Int J Gen Med
15
null
10.2147/IJGM.S338575
eng
2,022
null
null
2,022
1
6
[BACKGROUND] To explore the clinicopathological significance and prognostic value of thiopurine methyltransferase (TPMT) in patients with colon cancer by bioinformatics analysis. [MATERIALS AND METHODS] The clinicopathological information and TPMT expression data were downloaded from The Cancer Genome Atlas (TCGA) and ...
bioinformatics analysis; colon cancer; prognosis; thiopurine methyltransferase
null
null
null
null
null
35,023,868
Prominent Ear Correction Using Full-Thickness Cartilage Strip: An Incomplete Cutting Technique.
Annals of plastic surgery
Ann Plast Surg
88
2
10.1097/SAP.0000000000002899
eng
2,022
2
1
null
null
null
[BACKGROUND] Prominent ears are one of the most well-known facial disfigurements influencing youngsters. Approximately 5% of the population suffers from some degree of ear prominence. More than 200 techniques have been used for the surgical correction of prominent ears, referring that no single "best" method exists and...
null
0.608
112
Surgery
Medicine
2,022
35,023,807
Incidence of corneal adverse events in patients with multiple myeloma and their clinical and economic impact: A real-world retrospective cohort study.
Journal of medical economics
J Med Econ
25
1
10.1080/13696998.2022.2029088
eng
2,022
null
null
null
null
null
[AIMS] Ocular toxicities are common adverse events (AEs) associated with anticancer agents. There is a paucity of data documenting their impact on patient care. This study assessed the clinical and economic burden of corneal AEs and related symptoms (collectively termed corneal AEs) in patients receiving multiple myelo...
I; I00; I1; I10; Multiple myeloma; corneal adverse events; economic burden; healthcare resource utilization; hematology; real-world; toxicity
0.74
58
Health Policy
Medicine
2,022
35,023,501
THE BONE-BRAIN AXIS? BIOPSYCHOSOCIAL ASPECTS OF ORTHOPEDICS AND A MENTAL WELLBEING ACTION PLAN IN MUSCULOSKELETAL CARE.
Wiadomosci lekarskie (Warsaw, Poland : 1960)
Wiad Lek
74
11 cz 1
null
eng
2,021
null
null
null
null
null
[OBJECTIVE] The aim: To review the biopsychosocial aspects of psychiatric comorbidity in patients with musculoskeletal conditions and recommend a relevant mental health action plan. [PATIENTS AND METHODS] Materials and methods: Keywords (orthopedics, psychiatry, mental health) were used to list down and analyze the lit...
biopsychosocial model; mental health; orthopedics; psychiatry
null
null
null
null
null
35,023,287
Comparing effectiveness of first-line antiretroviral therapy between peri-urban and rural clinics in KwaZulu-Natal, South Africa.
HIV medicine
HIV Med
23
7
10.1111/hiv.13231
eng
2,022
8
null
2,022
1
12
[OBJECTIVES] Viral suppression (VS) is the hallmark of successful antiretroviral therapy (ART) programmes. We sought to compare clinic retention, virological outcomes, drug resistance and mortality between peri-urban and rural settings in South Africa after first-line ART. [METHODS] Beginning in July 2014, 1000 (500 pe...
clinic retention; disposition; drug resistance; virological failure; virological suppression
0.989
88
Health Policy; Pharmacology; Infectious Diseases
Medicine
2,022
35,023,242
Systematic review and meta-analysis of anal motor and rectal sensory dysfunction in male and female patients undergoing anorectal manometry for symptoms of faecal incontinence.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Colorectal Dis
24
5
10.1111/codi.16047
eng
2,022
5
null
2,022
1
30
[AIM] Manometry is the best established technique to assess anorectal function in faecal incontinence. By systematic review, pooled prevalences of anal hypotonia/hypocontractility and rectal hypersensitivity/hyposensitivity in male and female patients were determined in controlled studies using anorectal manometry. [ME...
anorectal manometry; faecal incontinence; hypersensitivity; hypocontractility; hyposensitivity; hypotonia
0.948
110
Gastroenterology
Medicine
2,022
35,023,213
Play-based groups for children with cerebral palsy and their parents: A qualitative interview study about the impact on mothers' well-being.
Child: care, health and development
Child Care Health Dev
48
4
10.1111/cch.12962
eng
2,022
7
null
2,022
2
1
[BACKGROUND] Cerebral palsy (CP) is the most common childhood physical disability in developed countries. Parents of children with CP experience difficulties that can result in reduced well-being. Health professionals supporting children with CP have been encouraged to focus on parental well-being as this forms part of...
cerebral palsy; child disability; groups; parents; social support; well-being
0.926
101
Pediatrics, Perinatology and Child Health; Public Health, Environmental and Occupational Health; Developmental and Educational Psychology
Medicine; Psychology
2,022
35,023,123
Prenatal Genetic Testing for X-Linked Hypohidrotic Ectodermal Dysplasia.
Advances in experimental medicine and biology
Adv Exp Med Biol
1339
null
10.1007/978-3-030-78787-5_41
eng
2,021
null
null
null
null
null
[INTRODUCTION] Hypohidrotic ectodermal dysplasia (HED) is an X-linked recessive disorder, characterised by abnormally developed ectodermal tissues (sweat glands, enamel, hair, nails). HED is caused by mutations of the EDA1 gene (Xq13.1) which codes for ectodysplasin A, a transmembrane signalling protein, which plays a ...
Ectodermal dysplasia; Mutation; Prenatal testing; X-linked recessive inheritance
null
null
null
null
null
35,023,097
Kisspeptin and the Genetic Obesity Interactome.
Advances in experimental medicine and biology
Adv Exp Med Biol
1339
null
10.1007/978-3-030-78787-5_15
eng
2,021
null
null
null
null
null
[BACKGROUND] Kisspeptin (encoded by the KISS1 gene in humans) is an excitatory neuromodulatory peptide implicated in multiple homeostatic systems, including anti-oxidation, glucose homeostasis, nutrition, locomotion, etc. Therefore, in the current obesity epidemic, kisspeptin is gaining increasing interest as a researc...
Genetic obesity; Homeostasis; Interactome; Kisspeptin; Kisspeptin signal transduction pathway; Stress; Systems biology
null
null
null
null
null
35,022,886
Application of interdisciplinary collaborative hospice care for terminal geriatric cancer patients: a prospective randomized controlled study.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
30
4
10.1007/s00520-022-06816-x
eng
2,022
4
null
2,022
1
12
[BACKGROUND] Hospice care (HC) is specialized medical care for terminal patients who are nearing the end of life. Interdisciplinary collaborative hospice care (ICHC) is where experts from different disciplines and patients/caregivers form a treatment team to establish shared patient care goals. However, the ICHC effica...
Geriatric cancer patients; Hospice care; Interdisciplinary collaborative hospice care; Life-sustaining treatments; Palliative care; Terminal patients
0.984
143
Oncology
Medicine
2,022
35,022,546
Associations between weight loss history and factors related to type 2 diabetes risk in the Stop Diabetes study.
International journal of obesity (2005)
Int J Obes (Lond)
46
5
10.1038/s41366-021-01061-4
eng
2,022
5
null
2,022
1
12
[BACKGROUND] Frequent weight loss attempts are related to maladaptive eating behaviours and higher body mass index (BMI). We studied associations of several type 2 diabetes (T2D) risk factors with weight loss history, defined as the frequency of prior weight loss attempts, among Finnish adults at increased risk for T2D...
null
1.438
258
Endocrinology, Diabetes and Metabolism; Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
35,022,177
Development and validation of a prehospital-stage prediction tool for traumatic brain injury: a multicentre retrospective cohort study in Korea.
BMJ open
BMJ Open
12
1
10.1136/bmjopen-2021-055918
eng
2,022
1
12
2,022
1
12
[OBJECTIVES] Predicting diagnosis and prognosis of traumatic brain injury (TBI) at the prehospital stage is challenging; however, using comprehensive prehospital information and machine learning may improve the performance of the predictive model. We developed and tested predictive models for TBI that use machine learn...
accident & emergency medicine; neurological injury; trauma management
1.059
176
Medicine
Medicine
2,022
35,022,158
COVID-19 Assessment and Testing in Rural Communities During the Pandemic: Cross-sectional Analysis.
JMIR public health and surveillance
JMIR Public Health Surveill
8
2
10.2196/30063
eng
2,022
2
8
2,022
2
8
[BACKGROUND] The COVID-19 pandemic exacerbated the need for urgent improvements in access to health care for rural, remote, and underserviced communities. The Renfrew County Virtual Triage and Assessment Centre (VTAC) was designed to provide access to COVID-19 testing and assessment with a family physician. The goal wa...
COVID-19; access; assessment; community paramed; digital health; healthcare; online health; pandemic; physician; testing; virtual care; virtual health
1.547
64
Health Informatics; Public Health, Environmental and Occupational Health
Medicine
2,022
35,022,079
MR-based radiomics-clinical nomogram in epithelial ovarian tumor prognosis prediction: tumor body texture analysis across various acquisition protocols.
Journal of ovarian research
J Ovarian Res
15
1
10.1186/s13048-021-00941-7
eng
2,022
1
12
2,022
1
12
[BACKGROUND] Epithelial ovarian cancer (EOC) is the most malignant gynecological tumor in women. This study aimed to construct and compare radiomics-clinical nomograms based on MR images in EOC prognosis prediction. [METHODS] A total of 186 patients with pathologically proven EOC were enrolled and randomly divided into...
Computer-aided diagnosis; Epithelial ovarian cancer; MR images; Prognosis; Radiomics
0.965
66
Obstetrics and Gynecology; Oncology
Medicine
2,022
35,022,052
Transformational Change in maternity services in England: a longitudinal qualitative study of a national transformation programme 'Early Adopter'.
BMC health services research
BMC Health Serv Res
22
1
10.1186/s12913-021-07375-3
eng
2,022
1
12
2,022
1
12
[BACKGROUND] Large system transformation in health systems is designed to improve quality, outcomes and efficiency. Using empirical data from a longitudinal study of national policy-driven transformation of maternity services in England, we explore the utility of theory-based rules regarding 'what works' in large syste...
Health Care Reform / organization & administration; Health Policy; Health systems change; Large-scale change; National Health Service
0.964
157
Health Policy
Medicine
2,022
35,022,039
Comparison of different feature extraction methods for applicable automated ICD coding.
BMC medical informatics and decision making
BMC Med Inform Decis Mak
22
1
10.1186/s12911-022-01753-5
eng
2,022
1
12
2,022
1
12
[BACKGROUND] Automated ICD coding on medical texts via machine learning has been a hot topic. Related studies from medical field heavily relies on conventional bag-of-words (BoW) as the feature extraction method, and do not commonly use more complicated methods, such as word2vec (W2V) and large pretrained models like B...
Automated ICD coding; BERT; Bag-of-words; Feature extraction; Interpretability; Word2vec
0.94
107
Health Policy; Computer Science Applications; Health Informatics
Computer Science; Medicine
2,022