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34,950,317
Chronic Obstructive Pulmonary Disease and Risk of Atrial Arrhythmias After ST-Segment Elevation Myocardial Infarction.
Journal of atrial fibrillation
J Atr Fibrillation
13
4
10.4022/jafib.2360
eng
2,020
12
null
2,020
12
31
[BACKGROUND] ST-segment elevation myocardial infarction (STEMI) and cardiac arrhythmias frequently occur in patients with chronic obstructive pulmonary disease (COPD). However, little is known about the association of COPD with the occurrence of atrial arrhythmias after STEMI. [METHODS] This retrospective analysis cons...
Atrial arrhythmias; Chronic obstructive pulmonary disease; STEMI
0.525
26
Cardiology and Cardiovascular Medicine
Medicine
2,020
34,949,914
Drug Repurposing: Deferasirox Inhibits the Anti-Apoptotic Activity of Mcl-1.
Drug design, development and therapy
Drug Des Devel Ther
15
null
10.2147/DDDT.S323077
eng
2,021
null
null
2,021
12
15
[INTRODUCTION] With the aim of repositioning commercially available drugs for the inhibition of the anti-apoptotic myeloid cell leukemia protein, Mcl-1, implied in various cancers, five molecules, highlighted from a published theoretical screening, were selected to experimentally validate their affinity toward Mcl-1. [...
Deferasirox; Mcl-1; NMR; docking; drug repurposing; dynamics
0.784
108
Pharmaceutical Science; Drug Discovery; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,021
34,949,911
Keratoconus and Visual Performance with Different Contact Lenses.
Clinical ophthalmology (Auckland, N.Z.)
Clin Ophthalmol
15
null
10.2147/OPTH.S345154
eng
2,021
null
null
2,021
12
16
[PURPOSE] To analyze the visual performance in contact lens wearers with keratoconus. [METHODS] A retrospective study including contact lens (CL) wearers was performed. The current best-corrected visual acuity with contact lens (BCVA-CL) and with spectacles (BCVA-S) correction, contrast sensitivity (CS) (by Metrovision...
contact lens; keratoconus; optical quality; visual performance
0.905
84
Ophthalmology
Medicine
2,021
34,949,623
Adequacy and timeliness of antenatal care visits among Ethiopian women: a community-based panel study.
BMJ open
BMJ Open
11
12
10.1136/bmjopen-2021-053357
eng
2,021
12
23
2,021
12
23
[OBJECTIVES] The purposes of the study are; (A) to identify whether Ethiopian women's antenatal care (ANC) visits are adequate and timely and (B) to explore factors that determine these. [DESIGN] Panel study design. [SETTING] Ethiopia. [PARTICIPANTS] A total of 2855 women nested within 217 enumeration areas. [PRIMARY O...
obstetrics; primary care; public health; reproductive medicine
0.982
176
Medicine
Medicine
2,021
34,949,519
Novel instrument to guide nurse-led consultations with parents of three-year-olds in school health services in Flanders: A feasibility study of SPARK36.
Journal of pediatric nursing
J Pediatr Nurs
64
null
10.1016/j.pedn.2021.12.001
eng
2,022
null
null
2,021
12
20
[BACKGROUND] In the framework of new legislation on School Health Services (SHS) in Flanders (Belgium), nurses lead a preventive consultation with every three-year-old child and its parent(s), with the aim of assessing risks in child development and potential parenting problems. This study assesses the feasibility of t...
Child development; Feasibility study; Nurse; Parenting; Primary care; Public health; School health service
0.566
78
Pediatrics
Nursing
2,022
34,949,509
Role of Mental Health in the Association Between E-Cigarettes and Cannabis Use.
American journal of preventive medicine
Am J Prev Med
62
3
10.1016/j.amepre.2021.09.012
eng
2,022
3
null
2,021
12
20
[INTRODUCTION] E-cigarette use may be associated prospectively with subsequent cannabis use among U.S. adolescents. However, it remains unclear whether this association differs by individual mental health status. This longitudinal study examines effect modifications by mental health status. [METHODS] The first 4 waves ...
null
2.181
260
Epidemiology; Public Health, Environmental and Occupational Health
Medicine
2,022
34,947,843
Development and Validation of a Mutational Burden-Associated LncRNA Signature for Improving the Clinical Outcome of Hepatocellular Carcinoma.
Life (Basel, Switzerland)
Life (Basel)
11
12
10.3390/life11121312
eng
2,021
11
28
2,021
11
28
[BACKGROUND] Long non-coding RNAs (lncRNAs) modulate numerous cellular processes, including DNA damage repair. Here, we investigated the clinical importance of lncRNAs associated with mutational burden in hepatocellular carcinoma (HCC). [METHODS] Prognosis-related lncRNAs associated with mutational burden were screened...
TP53; hepatocellular carcinoma; long non-coding RNA; mutational burden; prognosis
0.588
69
Biochemistry, Genetics and Molecular Biology; Ecology, Evolution, Behavior and Systematics; Paleontology; Space and Planetary Science
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Earth and Planetary Sciences
2,021
34,946,358
The Increasing Investment of Real Estate in the Health System-A Comparison between the USA and Europe.
Healthcare (Basel, Switzerland)
Healthcare (Basel)
9
12
10.3390/healthcare9121633
eng
2,021
11
25
2,021
11
25
[BACKGROUND] This study aimed to compare property development and increasing investment in real estate by the healthcare system organizations in the USA and Europe. Real estate investments have upsurged in healthcare due to the multiple benefits to patients and medical practitioners. [METHODS] The approach of acquiring...
Europe; USA; health system; investment; real estate
0.533
33
Health Policy
Medicine
2,021
35,002,264
Direct and Indirect Costs of Asthma Burden in Abu Dhabi: A Retrospective Analysis of Insurance Claims Data from 2015 to 2018.
ClinicoEconomics and outcomes research : CEOR
Clinicoecon Outcomes Res
13
null
10.2147/CEOR.S331499
eng
2,021
null
null
2,021
12
29
[PURPOSE] Asthma causes a high economic burden on the health-care system. Previous research on the cost of asthma in Abu Dhabi was in 2011 and revealed high medical costs. This work aimed to estimate both direct and indirect costs of asthma with trend analysis over a period of four years. [PATIENTS AND METHODS] All dat...
Abu Dhabi; asthma; direct cost; economic burden; indirect cost
0.445
40
Economics, Econometrics and Finance; Health Policy
Economics, Econometrics and Finance; Medicine
2,021
35,002,124
Clinical Features and Outcome of Stroke with COVID-19. COVID-19 Stroke Study Group (CSSG), India.
Annals of Indian Academy of Neurology
Ann Indian Acad Neurol
24
5
10.4103/aian.AIAN_122_21
eng
2,021
null
null
2,021
8
30
[BACKGROUND AND PURPOSE] Occurrence of stroke has been reported among patients with COVID-19. The present study compares clinical features and outcomes of stroke patients with and without COVID-19. [METHODS] The COVID-19 Stroke Study Group (CSSG) is a multicentric study in 18 sites across India to observe and compare t...
COVID-19; SARS-CoV-2; ischemic stroke; stroke; thrombolysis
0.394
46
Neurology
Medicine
2,021
35,001,953
Use of intraoperative mild hyperventilation to decrease the incidence of postoperative shoulder pain after laparoscopic gastric sleeve surgery: A prospective randomised controlled study.
Indian journal of anaesthesia
Indian J Anaesth
65
11
10.4103/ija.ija_576_21
eng
2,021
11
null
2,021
11
23
[BACKGROUND AND AIMS] Post-laparoscopic shoulder pain (PLSP) is a common problem. It is a referred type of pain resulting from irritation of phrenic nerve endings. Multiple manoeuvres were used to decrease its incidence with varying success rates. In this study, we tested the use of mild intraoperative hyperventilation...
Bariatric surgery; hyperventilation; laparoscopy; pain; shoulder
0.738
49
Anesthesiology and Pain Medicine
Medicine
2,021
35,001,813
Treadmill workouts alleviate neuropathic allodynia and scratching behavior in rats following thoracotomy.
Neurological research
Neurol Res
44
6
10.1080/01616412.2021.2024719
eng
2,022
6
null
2,022
1
10
[BACKGROUND] The aim of the experiment was to investigate the effects of treadmill exercise on postthoracotomy pain and the expression of spinal pro-inflammatory and anti-inflammatory cytokines. [METHODS] Animals were randomly distributed into four groups: (a) sham surgery, (b) rats following 60 min thoracotomy and rib...
Exercise; anti-inflammatory cytokine; postthoracotomy hypersensitivity; pro-inflammatory cytokine; scratching behavior; spinal cord
0.543
88
Medicine; Neurology; Neurology
Medicine; Neuroscience
2,022
35,001,472
Risk of major depressive disorder in adolescent and young adult cancer patients in Japan.
Psycho-oncology
Psychooncology
31
6
10.1002/pon.5881
eng
2,022
6
null
2,022
1
20
[OBJECTIVE] To estimate the risk of major depressive disorder (MDD) in adolescent and young adult (AYA) patients with cancer in Japan and identify risk factors for MDD among these patients. [METHODS] This was a matched cohort study using a large claims database in Japan. Included patients were aged 15-39 years, newly d...
adolescent; adult; cancer; depressive disorder; major; mood disorders; neoplasms; oncology; psycho-oncology; young adult
1.111
165
Experimental and Cognitive Psychology; Psychiatry and Mental Health; Oncology
Medicine; Psychology
2,022
35,001,360
Mesenchymal Tumors Involving the Pancreas: A Clinicopathologic Analysis and Review of the Literature.
Turk patoloji dergisi
Turk Patoloji Derg
38
1
10.5146/tjpath.2022.01567
eng
2,022
null
null
null
null
null
[OBJECTIVE] Most pancreatic tumors are epithelial, and, among these, more than 90% are of ductal origin. However, a variety of mesenchymal tumors may involve the pancreas and may manifest different clinicopathological characteristics. The literature on mesenchymal tumors in the pancreas is largely limited to individual...
null
null
null
null
null
null
35,000,633
Exploring theories for the exponential 16-year rise in incidence of necrotising otitis externa in England.
The Journal of laryngology and otology
J Laryngol Otol
136
10
10.1017/S0022215121004515
eng
2,022
10
null
2,022
1
10
[BACKGROUND] Necrotising otitis externa is a severe, life-threatening infection. Epidemiological data demonstrate a dramatic rise in reported cases in England from 2002 to 2017. The reasons for this remain elusive. [METHODS] A quantitative descriptive study was undertaken using epidemiological data from the Hospital Ep...
Diabetes Mellitus; Immunosuppression; Osteomyelitis; Otitis Externa
0.57
79
Medicine; Otorhinolaryngology
Medicine
2,022
35,000,544
Health-related quality of life among family caregivers of oesophageal cancer survivors one year after curative intended treatment - a nationwide population-based study.
Acta oncologica (Stockholm, Sweden)
Acta Oncol
61
3
10.1080/0284186X.2021.2023757
eng
2,022
3
null
2,022
1
8
[BACKGROUND] To investigate factors that might influence the quality of life of the family caregivers of oesophageal cancer patients. [MATERIAL AND METHODS] A cross-sectional study within a prospective, population-based nationwide cohort study including family caregivers to oesophageal cancer patients was conducted. Th...
Cancer survivorship; RAND-36; cancer treatment; family caregivers; surgical complications
0.957
124
Medicine; Radiology, Nuclear Medicine and Imaging; Hematology; Oncology
Medicine
2,022
35,000,467
Gene-environment interactions increase the risk of pediatric-onset multiple sclerosis associated with ozone pollution.
Multiple sclerosis (Houndmills, Basingstoke, England)
Mult Scler
28
9
10.1177/13524585211069926
eng
2,022
8
null
2,022
1
8
[BACKGROUND] We previously reported a relationship between air pollutants and increased risk of pediatric-onset multiple sclerosis (POMS). Ozone is an air pollutant that may play a role in multiple sclerosis (MS) pathoetiology. CD86 is the only non-HLA gene associated with POMS for which expression on antigen-presentin...
CD86; DRB1*15; Pediatric onset; multiple sclerosis; ozone pollution
null
null
null
null
null
35,000,430
Comparative Studies of Renin-Null Zebrafish and Mice Provide New Functional Insights.
Hypertension (Dallas, Tex. : 1979)
Hypertension
79
3
10.1161/HYPERTENSIONAHA.121.18600
eng
2,022
3
null
2,022
1
10
[BACKGROUND] The renin-angiotensin system is highly conserved across vertebrates, including zebrafish, which possess orthologous genes coding for renin-angiotensin system proteins, and specialized mural cells of the kidney arterioles, capable of synthesising and secreting renin. [METHODS] We generated zebrafish with CR...
actins; glycosylation; pericytes; renin; zebrafish
2.758
307
Internal Medicine
Medicine
2,022
35,000,368
Peak Voluntary Cough Flow and Oropharyngeal Dysphagia as Risk Factors for Pneumonia.
Annals of rehabilitation medicine
Ann Rehabil Med
45
6
10.5535/arm.21068
eng
2,021
12
null
2,021
12
31
[OBJECTIVE] To investigate the relationship between voluntary peak cough flow (PCF), oropharyngeal dysphagia, and pneumonia in patients who were evaluated with videofluoroscopic swallowing study (VFSS). [METHODS] Patients who underwent both VFSS and PCF measurement on the same day were enrolled retrospectively (n=821)....
Cough; Deglutition disorders; Peak expiratory flow rate; Pneumonia
0.468
47
Rehabilitation
Medicine
2,021
35,000,117
Serum Elabela level is related to endoscopic activity index in patients with active ulcerative colitis.
Irish journal of medical science
Ir J Med Sci
191
3
10.1007/s11845-021-02914-7
eng
2,022
6
null
2,022
1
8
[BACKGROUND] In ulcerative colitis patients, Elabela levels and the relation of Elabela with laboratory parameters is unknown. [AIM] The purpose of this study was to investigate the serum Elabela levels in UC patients and its relationship with other clinical and laboratory findings. [METHODS] Forty-three patients with ...
Elabela; Endoscopic activity index; Ulcerative colitis
0.467
46
Medicine
Medicine
2,022
35,000,096
Clinical utility of expanded NIPT for chromosomal abnormalities and etiology analysis of cytogenetic discrepancies cases.
Journal of assisted reproduction and genetics
J Assist Reprod Genet
39
1
10.1007/s10815-021-02351-6
eng
2,022
1
null
2,022
1
9
[PURPOSE] This study is to assess the performance of expanded noninvasive prenatal testing (NIPT) in detecting chromosome aneuploidies and chromosome copy number variants (CNVs), and elucidate the discordant cases between NIPT and fetal karyotype. [METHODS] A total of 2139 single pregnancies have been recruited and seq...
CNVs; Discordant results; Expanded NIPT; Fetal mosaicism; PPV; Placental mosaicism
0.844
101
Developmental Biology; Genetics; Genetics; Medicine; Obstetrics and Gynecology; Reproductive Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,000,057
Identification of Germline Non-coding Deletions in XIAP Gene Causing XIAP Deficiency Reveals a Key Promoter Sequence.
Journal of clinical immunology
J Clin Immunol
42
3
10.1007/s10875-021-01188-z
eng
2,022
4
null
2,022
1
9
[PURPOSE] X-linked inhibitor of apoptosis protein (XIAP) deficiency, also known as the X-linked lymphoproliferative syndrome of type 2 (XLP-2), is a rare immunodeficiency characterized by recurrent hemophagocytic lymphohistiocytosis, splenomegaly, and inflammatory bowel disease. Variants in XIAP including missense, non...
Deletion; Inherited immunodeficiency; Non-coding exon; Promoter; X-linked inhibitor of apoptosis
2.151
119
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
35,000,041
Male patients with papillary thyroid cancer have a higher risk of extranodal extension.
International journal of clinical oncology
Int J Clin Oncol
27
4
10.1007/s10147-021-02109-1
eng
2,022
4
null
2,022
1
8
[BACKGROUND] There is a sex disparity in papillary thyroid cancer (PTC). Male sex is associated with a higher likelihood of advanced stage disease. This study aimed to examine the significance of sex for extranodal extension (ENE) in PTC. [METHODS] We reviewed the data of PTC patients who had undergone initial surgical...
Extranodal extension; Gender; Lymph node; Metastasis; Papillary thyroid cancer
0.968
78
Medicine; Surgery; Hematology; Oncology
Medicine
2,022
34,999,942
The role of aspirin dose and initiation time in the prevention of preeclampsia and corresponding complications: a meta-analysis of RCTs.
Archives of gynecology and obstetrics
Arch Gynecol Obstet
305
6
10.1007/s00404-021-06349-4
eng
2,022
6
null
2,022
1
9
[PURPOSE] To investigate the role of different dosages and initial times of aspirin in preeclampsia prevention. [METHODS] This meta-analysis was performed based on randomized-control trials (RCTs). RCTs of women assigned to receive low-dose aspirin, placebo, or no treatment were included. Preeclampsia and corresponding...
Aspirin; Meta-analysis; Preeclampsia; Pregnancy complication; Prevention
0.727
90
Medicine; Obstetrics and Gynecology
Medicine
2,022
34,999,903
Characteristics, image findings and clinical outcome of moderate and severe traumatic brain injury among severely injured children: a population-based cohort study.
European journal of trauma and emergency surgery : official publication of the European Trauma Society
Eur J Trauma Emerg Surg
48
6
10.1007/s00068-021-01820-y
eng
2,022
12
null
2,022
1
9
[PURPOSE] The aim of this study was to explore patient and injury characteristics, image findings, short-term clinical outcome and time trends of moderate and severe traumatic brain injury in severely injured children. [METHODS] This study is an observational cohort study based on prospectively collected data from an i...
Glasgow Coma Scale; Glasgow Outcome Scale; Mortality; Paediatric trauma; Traumatic brain injury
0.565
54
Critical Care and Intensive Care Medicine; Emergency Medicine; Orthopedics and Sports Medicine; Surgery
Medicine
2,022
34,999,825
Associations of Smokeless Tobacco Use With Cardiovascular Disease Risk: Insights From the Population Assessment of Tobacco and Health Study.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Nicotine Tob Res
24
7
10.1093/ntr/ntab258
eng
2,022
6
15
null
null
null
[INTRODUCTION] Cigarette smoking is strongly associated with the development of cardiovascular disease (CVD). However, evidence is limited as to whether smokeless tobacco (ST) use is associated with CVD. [AIMS AND METHODS] Using data from 4347 adults in the Population Assessment of Tobacco and Health Study (2013-2014),...
null
null
null
null
null
null
34,999,632
Surgical Treatment of the Intraspinal Rib Head Dislocation in Children With Dystrophic Scoliosis Secondary to Type 1 Neurofibromatosis.
Journal of pediatric orthopedics
J Pediatr Orthop
42
3
10.1097/BPO.0000000000002048
eng
2,022
3
1
null
null
null
[BACKGROUND] The purpose of this study was to explore the surgical treatment of intraspinal rib head dislocation (IRH) in children with dystrophic scoliosis secondary to type 1 neurofibromatosis (NF1-DS). [METHODS] From 2006 to 2019, 32 of 128 patients with NF1-DS were found to have IRH and enrolled in this study. Ther...
null
null
null
null
null
null
34,999,444
Cognitive development after perinatal unilateral infarctions: No evidence for preferential sparing of verbal functions.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
Eur J Paediatr Neurol
37
null
10.1016/j.ejpn.2021.12.007
eng
2,022
3
null
2,021
12
12
[BACKGROUND] Even children with extensive perinatal left-sided lesions have been reported to show normal language functions based on right-hemispheric language reorganization. This reorganization can lead to deficits in originary right hemispheric functions ("crowding hypothesis"). In a previous study, however, we iden...
Cognitive performance; Crowding hypothesis; Early brain lesion; Functional magnetic resonance imaging; Language lateralization
0.885
79
Medicine; Pediatrics, Perinatology and Child Health; Neurology
Medicine
2,022
34,999,328
Multiple vitamin co-exposure and mortality risk: A prospective study.
Clinical nutrition (Edinburgh, Scotland)
Clin Nutr
41
2
10.1016/j.clnu.2021.12.010
eng
2,022
2
null
2,021
12
10
[BACKGROUND AND AIMS] Existing epidemiological studies explored the associations of circulating vitamins and mortality focusing on individual vitamin effects, and controversial findings were obtained. The joint effects of multiple vitamin co-exposure are worth studying. The study aimed to elucidate the associations of ...
Co-exposure; K-means clustering; Mortality; Vitamin
1.658
183
Critical Care and Intensive Care Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
34,999,308
Effect of cerebrospinal fluid drainage on clinical outcomes following aneurysmal subarachnoid hemorrhage.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
J Clin Neurosci
97
null
10.1016/j.jocn.2021.12.026
eng
2,022
3
null
2,022
1
6
[OBJECTIVES] We study the relationship between external ventricular drainage (EVD) of cerebrospinal fluid output and functional outcomes in patients with aneurysmal subarachnoid hemorrhage (aSAH). [METHODS] A retrospective chart review of patients presenting to a single center with aSAH was performed. The primary outco...
Aneurysm; Cerebrospinal fluid; Clinical outcomes; External ventricular drain; Subarachnoid hemorrhage; Vasospasm
0.54
104
Medicine; Surgery; Neurology; Neurology; Physiology
Medicine; Neuroscience
2,022
34,999,110
Gene therapy with Pellino-1 improves perfusion and decreases tissue loss in Flk-1 heterozygous mice but fails in MAPKAP Kinase-2 knockout murine hind limb ischemia model.
Microvascular research
Microvasc Res
141
null
10.1016/j.mvr.2022.104311
eng
2,022
5
null
2,022
1
7
[OBJECTIVES] In the United States, over 8.5 million people suffer from peripheral arterial disease (PAD). Previously we reported that Pellino-1(Peli1) gene therapy reduces ischemic damage in the myocardium and skin flaps in Flk-1 [Fetal Liver kinase receptor-1 (Flk-1)/ Vascular endothelial growth factor receptor-2/VEGF...
Hind limb ischemia; Ischemic score; Peli1; Perfusion; VEGF signaling
0.74
103
Biochemistry; Cardiology and Cardiovascular Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,998,584
Prosthetic complications with mandibular bar-retained implant overdentures having distal attachments and metal frameworks: A 2- to 12-year retrospective analysis.
The Journal of prosthetic dentistry
J Prosthet Dent
130
4
10.1016/j.prosdent.2021.11.016
eng
2,023
10
null
2,022
1
5
[STATEMENT OF PROBLEM] Long-term reports on 2-implant-retained overdentures having metal frameworks and bars containing distal attachments are scarce. [PURPOSE] The purpose of this retrospective study was to evaluate prosthetic complications with 2-implant-retained mandibular overdentures with metal frameworks having e...
null
1.177
160
Medicine; Oral Surgery
Dentistry; Medicine
2,023
34,998,434
Identification of a five-miRNA signature as a novel potential prognostic biomarker in patients with nasopharyngeal carcinoma.
Hereditas
Hereditas
159
1
10.1186/s41065-021-00214-9
eng
2,022
1
8
2,022
1
8
[BACKGROUND] MicroRNAs (miRNAs) are involved in the prognosis of nasopharyngeal carcinoma (NPC). This study used clinical data and expression data of miRNAs to develop a prognostic survival signature for NPC patients to detect high-risk subject. [RESULTS] We identified 160 differentially expressed miRNAs using RNA-Seq ...
GEO; KEGG; Nasopharyngeal carcinoma; Prognostic; miRNA
0.565
57
Medicine; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,998,399
The RNA-binding protein GRSF1 promotes hepatocarcinogenesis via competitively binding to YY1 mRNA with miR-30e-5p.
Journal of experimental & clinical cancer research : CR
J Exp Clin Cancer Res
41
1
10.1186/s13046-021-02217-w
eng
2,022
1
8
2,022
1
8
[BACKGROUND] Dysregulation of RNA binding protein (RBP) expression has been confirmed to be causally linked with tumorigenesis. The detailed biological effect and underlying mechanisms of the RBP GRSF1 in hepatocellular carcinoma (HCC) remain unclear. [METHODS] HCC cells with stable knockdown of GRSF1 were established ...
GRSF1; HCC; RBP; YY1; miR-30e-5p
null
null
null
null
null
34,998,215
"Changed our lives": Psychosocial issues experienced by families of early adolescents with leukemia.
European journal of oncology nursing : the official journal of European Oncology Nursing Society
Eur J Oncol Nurs
56
null
10.1016/j.ejon.2021.102077
eng
2,022
2
null
2,021
12
23
[PURPOSE] This research aimed to explore psychosocial problems experienced by families of early adolescents with leukemia. [METHOD] This phenomenology research was done during December 2019-August 2020 and involved eighteen families (47 family members) of early adolescents (10-14 years old) with leukemia. Participants ...
Adolescent; Family experiences; Leukemia; Psychological problems; Social isolation
0.68
74
Oncology; Medicine
Medicine; Nursing
2,022
34,998,116
Screening for autism spectrum disorder in deaf adults with intellectual disability: Feasibility and accuracy of two autism screening instruments.
Research in developmental disabilities
Res Dev Disabil
122
null
10.1016/j.ridd.2021.104167
eng
2,022
3
null
2,022
1
5
[BACKGROUND] There is a lack of autism screening instruments for deaf or hard of hearing (DHH) adults with intellectual disability. [AIMS] This study examined the diagnostic validity of the Pervasive Developmental Disorder in Mental Retardation Scale and the Diagnostic Behavioral Assessment for autism spectrum disorder...
Adults; Assessment; Autism screening; Deaf and hard of hearing; DiBAS-R; Diagnosis; Intellectual disability; PDD-MRS
0.774
117
Clinical Psychology; Developmental and Educational Psychology
Psychology
2,022
34,997,999
Impact of meningococcal C conjugate vaccine on incidence of invasive meningococcal disease in an 18-year time series in Brazil and in distinct Brazilian regions.
Tropical medicine & international health : TM & IH
Trop Med Int Health
27
3
10.1111/tmi.13718
eng
2,022
3
null
2,022
2
1
[OBJECTIVE] To evaluate the impact of meningococcal C conjugate (MCC) vaccine in Brazil. [METHODS] Ecological study assessing all invasive meningococcal disease (IMD) and meningococcal C disease (MenC) cases reported in all age groups, from 2001 to 2019. MCC was implemented in 2010. Data were collected on the DATASUS p...
children; meningococcal meningitis; public health; vaccination
null
null
null
null
null
34,997,748
Assessment of criterion validity of personality disorder diagnosis in adolescents and relations between attachment style and personality disorder diagnosis.
Psychiatria polska
Psychiatr Pol
55
5
10.12740/PP/OnlineFirst/119778
eng
2,021
10
31
2,021
10
31
[OBJECTIVES] Assessment of criterion validity and temporal stability of personality disorder diagnosis in adolescents and relationships between attachment styles and personality disorder diagnosis. [METHODS] 50 adolescents (46 girls and 4 boys, aged 15-17) hospitalized at the department of child and adolescent psychiat...
null
0.357
35
Medicine; Psychiatry and Mental Health
Medicine
2,021
34,997,364
Barriers and facilitators to taking CDK4/6 inhibitors among patients with metastatic breast cancer: a qualitative study.
Breast cancer research and treatment
Breast Cancer Res Treat
192
2
10.1007/s10549-022-06518-2
eng
2,022
4
null
2,022
1
7
[PURPOSE] Most studies of adherence to treatment for breast cancer have focused on early-stage patients. Findings from these studies may not generalize to patients with metastatic breast cancer (MBC). The objective of this study was to identify barriers and facilitators of adherence to cyclin-dependent kinase 4/6 (CDK4...
Breast cancer; CDK4/6 inhibitors; Medication adherence; Metastatic breast cancer; Oral medication; Social ecologic model
1.442
184
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,996,491
INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma.
Journal of experimental & clinical cancer research : CR
J Exp Clin Cancer Res
41
1
10.1186/s13046-021-02216-x
eng
2,022
1
7
2,022
1
7
[BACKGROUND] Increasing evidence has suggested inositol polyphosphate 5-phosphatase family contributes to tumorigenesis and tumor progression. However, the role of INPP5F in hepatocellular carcinoma (HCC) and its underlying mechanisms is unclear. [METHODS] The expression of INPP5F in HCC was analyzed in public database...
ASPH; HCC; INPP5F; Notch signaling pathway; Nuclear-cytoplasmic shuttling
null
null
null
null
null
34,996,324
Longitudinal assessment of disability amongst patients of bipolar and unipolar depressive disorders presenting to a tertiary care center in North India.
The International journal of social psychiatry
Int J Soc Psychiatry
69
1
10.1177/00207640211070158
eng
2,023
2
null
2,022
1
7
[OBJECTIVES] To assess and compare the changes in disability scores associated with Bipolar Depression (BD) and Unipolar Depression (UD) over 1 year. [METHODS] A longitudinal study was taken up in adults diagnosed with unipolar or bipolar depressive disorder with current depressive episode. Diagnosis was made according...
Disability; bipolar depression; depressive disorders; mood disorders; unipolar depression
1.649
86
Medicine; Psychiatry and Mental Health
Medicine
2,023
34,996,101
Craniomaxillofacial Changes Using High-Pull J-Hook Headgear and Mini-Implant Anchorage in Adolescents: A Structural Superimposition Method.
The Journal of clinical pediatric dentistry
J Clin Pediatr Dent
45
6
10.17796/1053-4625-45.6.11
eng
2,021
12
1
null
null
null
[OBJECTIVE] The aim of this study was to compare the craniomaxillofacial changes when using high-pull J-hook headgear (HPJH) and mini-implants (MIs) as maxillary anchorage in adolescents. [STUDY DESIGN] 40 female adolescents with dentoalvolar protrusion were divided into 2 groups; the HPJH group (n=20) and the MI group...
Anchorage; High-pull J-hook headgear; Mini-implant; Structural superimposition
0.358
52
Dentistry; Medicine; Pediatrics, Perinatology and Child Health
Dentistry; Medicine
2,021
34,995,834
Leu226Trp CACNA1A variant associated with juvenile myoclonic epilepsy with and without intellectual disability.
Clinical neurology and neurosurgery
Clin Neurol Neurosurg
213
null
10.1016/j.clineuro.2021.107108
eng
2,022
2
null
2,021
12
30
[OBJECTIVE] Epilepsy is a disease of Central Nervous System (CNS) characterized by abnormal brain activity and recurrent seizures and is considered a clinically and genetically heterogeneous disease. Here, we investigated pathogenic genetic alteration and described the clinical characteristics of three Iranian family m...
Idiopathic generalized epilepsy; Intellectual disability; Juvenile myoclonic epilepsy; Psychiatric disorder; Voltage-gated channel
0.538
89
Medicine; Surgery; Neurology
Medicine
2,022
34,995,826
Surgical Reconstruction of a Traumatic Superior Sagittal Sinus Injury Using Synthetic Vascular Graft in a Resource-Limited Civilian Field Hospital During the Syrian Civil War.
World neurosurgery
World Neurosurg
159
null
10.1016/j.wneu.2021.12.116
eng
2,022
3
null
2,022
1
4
[BACKGROUND] Traumatic dural sinus injuries following penetrating brain injury are rare but are often associated with significant morbidity and mortality. The management of significant defects is operative and can be challenging. In modern civilian practice, patients with these injuries typically receive extensive preo...
Conflict; PTFE graft; Superior sagittal sinus; Syria; Trauma
0.591
123
Neurology; Surgery
Medicine
2,022
34,995,576
Comprehensive analysis of the exocytosis pathway genes in cervical cancer.
The American journal of the medical sciences
Am J Med Sci
363
6
10.1016/j.amjms.2021.12.008
eng
2,022
6
null
2,022
1
5
[BACKGROUND] Cervical cancer (CC) is the fourth most common gynecological malignancy globally. This suggests the need for improved markers for prognosis, better understanding of the molecular mechanism, and targets for therapy. The defective exocytosis pathway is proposed as bona fide drivers of carcinogenesis. This st...
Bioinformatics analysis; Cervical cancer; Drug targets; Exocytosis; Overall survival
0.662
106
Medicine
Medicine
2,022
34,995,487
Pitfalls of Surgeon-Engineer Communication and the Effect of In-House Engineer Training During Digital Planning of Patient-Specific Implants for Orbital Reconstruction.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
J Oral Maxillofac Surg
80
4
10.1016/j.joms.2021.12.003
eng
2,022
4
null
2,021
12
15
[PURPOSE] The use of patient-specific implants for reconstruction of complex orbital floor defects is increasing and requires communication with an industry partner, which warrants investigation. Therefore, the aim of this study was to evaluate the effects of in-house training of engineers on such communication as well...
null
0.649
147
Oral Surgery; Otorhinolaryngology; Surgery
Dentistry; Medicine
2,022
34,995,471
Genotype-Guided Antiplatelet Therapy Versus Standard Therapy for Patients with Coronary Artery Disease: An Updated Systematic Review and Meta-Analysis.
Journal of pharmacy pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
J Pharm Pharm Sci
25
null
10.18433/jpps32140
eng
2,022
null
null
null
null
null
[OBJECTIVE] Previous studies on the efficacy and safety of genotype-guided antiplatelet therapy in patients with coronary artery disease (CAD) or undergoing percutaneous coronary intervention (PCI) have been inconclusive. [AIM] We conducted a meta-analysis to evaluate if the genotype-guided antiplatelet strategy is sup...
null
null
null
null
null
null
34,995,367
Single-dose antibiotic therapy for urinary infections during pregnancy: A systematic review and meta-analysis of randomized clinical trials.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Int J Gynaecol Obstet
159
1
10.1002/ijgo.14087
eng
2,022
10
null
2,022
1
26
[BACKGROUND] During pregnancy, urinary infections are an important cause of maternofetal morbidity and mortality and may lead to several complications. [OBJECTIVE] To verify whether the use of antibiotic therapy in a single dose when compared with multiple doses in lower tract urinary infections during pregnancy is eff...
antibiotic; bacteriuria; cystitis; infection; pregnancy; single dose
null
null
null
null
null
34,995,104
Demographic and Clinical Predictors of Engaging in Tobacco Cessation Counseling at a Comprehensive Cancer Center.
JCO oncology practice
JCO Oncol Pract
18
5
10.1200/OP.21.00458
eng
2,022
5
null
2,022
1
7
[PURPOSE] To address challenges promoting tobacco cessation in oncology settings, it is important to understand characteristics associated with patient engagement in tobacco cessation treatment. This analysis examined predictors of participating in at least one tobacco cessation counseling session among patients referr...
null
1.349
85
Health Policy; Oncology; Oncology
Medicine; Nursing
2,022
34,994,890
Laparoscopic Segmentectomy IV Using Hepatic Round Ligament Approach Combined with Fluorescent Negative Staining Method.
Annals of surgical oncology
Ann Surg Oncol
29
5
10.1245/s10434-021-11221-5
eng
2,022
5
null
2,022
1
7
[BACKGROUND] Laparoscopic segmentectomy, which maximizes the preservation of the functional hepatic reserve and the possibility for future repeat hepatectomy while ensuring adequate surgical margin, is a feasible alternative to hemihepatectomy for hepatocellular carcinoma (HCC) (Vigano et al. in Ann Surg 270(5):842-851...
null
1.133
210
Surgery; Oncology
Medicine
2,022
34,994,768
Visual Field Characteristics in East Asian Patients With Occult Macular Dystrophy (Miyake Disease): EAOMD Report No. 3.
Investigative ophthalmology visual science
Invest Ophthalmol Vis Sci
63
1
10.1167/iovs.63.1.12
eng
2,022
1
3
null
null
null
[PURPOSE] The purpose of this study was to investigate the perimetric features and their associations with structural and functional features in patients with RP1L1-associated occult macular dystrophy (OMD; i.e. Miyake disease). [METHODS] In this international, multicenter, retrospective cohort study, 76 eyes of 38 pat...
null
null
null
null
null
null
34,994,742
Heterogeneity of cognitive profiles in students with borderline intellectual functioning.
Psychiatria polska
Psychiatr Pol
55
4
10.12740/PP/123165
eng
2,021
8
31
2,021
8
31
[OBJECTIVES] Borderline intellectual functioning (BIF) is aclinical entity of polyetiological nature which manifests in heterogeneity of cognitive deficits. The aim of this study was to identify groups of homogenous cognitive profiles within a heterogeneous population of students with BIF. [METHODS] Cognitive profiles ...
borderline intellectual functioning; cognitive profiles; intelligence quotient
0.357
35
Medicine; Psychiatry and Mental Health
Medicine
2,021
34,994,650
Tumor-Specific and Tumor-Agnostic Molecular Signatures Associated With Response to Immune Checkpoint Inhibitors.
JCO precision oncology
JCO Precis Oncol
5
null
10.1200/PO.21.00008
eng
2,021
11
null
null
null
null
[PURPOSE] Next-generation sequencing (NGS) testing is being incorporated into routine standard of care for patients with cancer. Immune checkpoint inhibitors (CPIs) are approved for use in both tumor-specific and tumor-agnostic indications. We sought to determine tumor type-specific or tumor-agnostic correlations betwe...
null
2.116
56
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,994,523
Association of tumor necrosis factor-α inhibitors and liver cirrhosis in patients with rheumatoid arthritis: A nationwide population-based nested case-control study.
International journal of rheumatic diseases
Int J Rheum Dis
25
3
10.1111/1756-185X.14272
eng
2,022
3
null
2,022
1
7
[AIM] Results from various studies are controversial regarding long-term hepatic effects of tumor necrosis factor (TNF)-α inhibitors. Here we aimed to investigate the development of liver cirrhosis with TNF-α inhibitors use in patients with rheumatoid arthritis (RA). [METHOD] This nested case-control study was based on...
adalimumab; cirrhosis; etanercept; rheumatoid arthritis
0.715
62
Rheumatology
Medicine
2,022
34,994,494
Acquired mild cognitive impairment in adults with Down syndrome: Age-related prevalence derived from single point assessment data normed by degree of intellectual disability.
International journal of geriatric psychiatry
Int J Geriatr Psychiatry
37
2
10.1002/gps.5674
eng
2,022
2
null
null
null
null
[BACKGROUND] Individuals with Down syndrome (DS) are at significant risk for early onset Alzheimer's disease (AD), likely due to the triplication of genes on chromosome 21 that facilitate AD neuropathology. To aid the effective early diagnosis of dementia in DS, we demonstrate the strategy of using single point assessm...
Alzheimer's disease; Down syndrome; ageing; dementia; intellectual disability; mild cognitive impairment; neuropsychological assessment
1.232
157
Geriatrics and Gerontology; Psychiatry and Mental Health
Medicine
2,022
34,994,347
Pharmacological Management of Atrial Fibrillation: A Century of Expert Opinions in Cecil Textbook of Medicine.
American journal of therapeutics
Am J Ther
29
1
10.1097/MJT.0000000000001464
eng
null
null
null
null
null
null
[BACKGROUND] Advances in drug therapy for atrial fibrillation (AF) have had a significant impact on the quality of life of a substantial majority of affected persons, which has contributed to a remarkable decrease in the frequency and severity of thromboembolic complications, hospitalizations, and mortality. [STUDY QUE...
null
null
null
null
null
null
34,994,092
Efficacy and safety of EBUS-TBNA under conscious sedation with meperidine and midazolam.
Thoracic cancer
Thorac Cancer
13
4
10.1111/1759-7714.14286
eng
2,022
2
null
2,022
1
7
[BACKGROUND] According to the guidelines, endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) is the technique of choice for the diagnosis of mediastinal involvement in lung cancer; it is also useful for other mediastinal malignancies and benign pathology. Nevertheless, there is still discussio...
EBUS-TBNA; bronchoscopy; meperidine; midazolam; sedation
0.73
55
Medicine; Oncology; Pulmonary and Respiratory Medicine
Medicine
2,022
34,993,994
Demographic, parental and home environment correlates of traditional and mobile screen time in preschool-aged children.
Child: care, health and development
Child Care Health Dev
48
4
10.1111/cch.12958
eng
2,022
7
null
2,022
1
17
[OBJECTIVES] Research on the correlates of screen time in young children, that could be targeted in future interventions to improve healthy development, has primarily focused on TV viewing with little consideration of mobile devices. The objectives of this study were to examine the associations between a range of demog...
child development; correlates; demographics; mobile; preschoolers; screen time; traditional screen time
0.926
101
Pediatrics, Perinatology and Child Health; Public Health, Environmental and Occupational Health; Developmental and Educational Psychology
Medicine; Psychology
2,022
34,993,096
Evaluation of semi-quantitative measures of [18]F-flutemetamol PET for the clinical diagnosis of Alzheimer's disease.
Quantitative imaging in medicine and surgery
Quant Imaging Med Surg
12
1
10.21037/qims-21-188
eng
2,022
1
null
null
null
null
[BACKGROUND] [18]F-flutemetamol positron emission tomography (PET) is used to assess cortical amyloid-β burden in patients with cognitive impairment to support a clinical diagnosis. Visual classification is the most widely used method in clinical practice although semi-quantification is beneficial to obtain an objectiv...
Centiloid; Flutemetamol; amyloid-beta; positron emission tomography (PET); quantification
0.664
50
Radiology, Nuclear Medicine and Imaging
Medicine
2,022
34,993,095
Evaluation of comprehensive myocardial contractility in children with Kawasaki disease by cardiac magnetic resonance in a large single center.
Quantitative imaging in medicine and surgery
Quant Imaging Med Surg
12
1
10.21037/qims-20-1402
eng
2,022
1
null
null
null
null
[BACKGROUND] Children with Kawasaki disease (KD) and coronary artery lesions (CALs) can develop myocardial ischemia, fibrosis, and abnormal contractility. We aimed to assess the association between myocardial mechanical deformation with myocardial fibrosis, ischemia, and CALs. [METHODS] In total, 76 KD and 20 healthy v...
Cardiac magnetic resonance (CMR); Kawasaki disease (KD); coronary artery aneurysm (CAA); feature tracking; myocardial fibrosis; thrombosis
0.664
50
Radiology, Nuclear Medicine and Imaging
Medicine
2,022
34,992,894
Intravenous Tranexamic Acid Decreases Blood Transfusions and Blood Loss for Patients with Surgically Treated Hip Fractures.
Geriatric orthopaedic surgery rehabilitation
Geriatr Orthop Surg Rehabil
12
null
10.1177/21514593211063668
eng
2,021
null
null
2,021
12
20
[INTRODUCTION] Tranexamic acid can decrease blood loss related to surgery and trauma. The primary objective of this study is to examine if the use of a single dose of peri-operative TXA significantly decreases the rate of allogenic blood transfusions in the setting of operative care of hip fractures. Secondary objectiv...
TXA; blood transfusion; hip fracture surgery; tranexamic acid
null
null
null
null
null
34,992,700
The impact of humanoid robot presence in the paediatric emergency department waiting room: A prospective cohort study.
Paediatrics child health
Paediatr Child Health
26
8
10.1093/pch/pxab027
eng
2,021
12
null
2,021
6
19
[BACKGROUND] The waiting room represents families' first point of contact with the emergency department (ED). We wished to study if a humanoid robot technology presence in the waiting room would improve satisfaction and decrease anxiety for caregivers in the paediatric ED. [METHODS] This observational cohort study was ...
Digital technology; Emergency department; Paediatrics; Waiting room
null
null
null
null
null
34,992,412
Composite Inflammatory Indicators as Early Predictor of Intra-abdominal Infections after General Surgery.
Journal of inflammation research
J Inflamm Res
14
null
10.2147/JIR.S340745
eng
2,021
null
null
2,021
12
21
[OBJECTIVE] To identify rapid and accurate early diagnostic indicators for intra-abdominal infection (IAI) after general surgery. [METHODS] We conducted a retrospective analysis of 3,810 general surgical patients in our hospital from August 2017 to July 2018. The predictive value of PCT, CRP, TNFα, and IL6 on postopera...
C-reactive protein; IL6; intra-abdominal infection; procalcitonin
1.088
58
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,021
34,992,367
Polymeric Nanocarriers for Effective Synergistic Action of Sorafenib Tosylate and Gold-sensitized Gamma Radiation Against HepG2 Cells.
International journal of nanomedicine
Int J Nanomedicine
16
null
10.2147/IJN.S331909
eng
2,021
null
null
2,021
12
23
[PURPOSE] One of the key parameters towards effective and synergistic combinatorial anticancer therapeutic models is the nanocarrier. Nearly all previous studies have been limited to one nanocarrier for one drug. However, a comparative study on two polymeric nanocarriers for the same drug against the same cancer cell a...
PCL; PLGA; biodegradable polymers; drug delivery; flow cytometry; radiotherapy
1.032
193
Bioengineering; Biomaterials; Biophysics; Drug Discovery; Medicine; Organic Chemistry; Pharmaceutical Science; Nanoscience and Nanotechnology
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,021
34,992,364
Anti-Acid Biomimetic Dentine Remineralization Using Inorganic Silica Stabilized Nanoparticles Distributed Electronspun Nanofibrous Mats.
International journal of nanomedicine
Int J Nanomedicine
16
null
10.2147/IJN.S331321
eng
2,021
null
null
2,021
12
21
[BACKGROUND] To manage the sharp pain of dentine hypersensitivity, various materials are utilized to conduct dentine remineralization. However, many prior materials are limited with their single function and complicated operations. In this study, silica and calcium (strontium) carbonates mineralized nano cellulose fibr...
dentine hypersensitivity; electrospinning; mineralization; silica; strontium carbonates
1.032
193
Bioengineering; Biomaterials; Biophysics; Drug Discovery; Medicine; Organic Chemistry; Pharmaceutical Science; Nanoscience and Nanotechnology
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,021
34,991,981
Impact of a pharmacist-run refill and prior authorization program on physician workload.
Journal of the American Pharmacists Association : JAPhA
J Am Pharm Assoc (2003)
62
3
10.1016/j.japh.2021.12.002
eng
2,022
null
null
2,021
12
7
[BACKGROUND] Pharmacist-led programs centralizing prescription renewals and prior authorization processing have been implemented within health care systems; however, their impact on physician efficiency and the perception of impact on workload are unknown. [OBJECTIVES] The primary objective of this study was to measure...
null
0.455
75
Pharmacology; Pharmacy; Pharmacology
Health Professions; Nursing; Pharmacology, Toxicology and Pharmaceutics
2,022
34,991,968
A Lung Cancer Screening Education Program Impacts both Referral Rates and Provider and Medical Assistant Knowledge at Two Federally Qualified Health Centers.
Clinical lung cancer
Clin Lung Cancer
23
4
10.1016/j.cllc.2021.12.002
eng
2,022
6
null
2,021
12
12
[BACKGROUND] Federally Qualified Health Centers (FQHCs) serve minority and low-socioeconomic populations and provide care to high-risk smokers. These centers frequently experience barriers, including low provider and medical assistant (MA) knowledge around lung cancer screening (LCS). Subsequent low LCS referral rates ...
FQHCs; LCS barriers; LDCT; Underserved populations
1.137
78
Pulmonary and Respiratory Medicine; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,991,954
Experiencing Sexual Assault and/or Stalking-Related Behavior is Associated with Binge Drinking and Substance Use Consequences in Deployed U.S. Servicewomen.
Women's health issues : official publication of the Jacobs Institute of Women's Health
Womens Health Issues
32
4
10.1016/j.whi.2021.12.002
eng
2,022
null
null
2,022
1
3
[BACKGROUND] Being deployed is a risk factor for poor postdeployment mental health outcomes in U.S. servicewomen, including harmful drinking. However, to our knowledge, no studies have examined deployment-related sexual assault and exposure to stalking-related behavior in relation to binge drinking and substance use co...
null
1.122
75
Health; Maternity and Midwifery; Obstetrics and Gynecology; Public Health, Environmental and Occupational Health
Medicine; Nursing; Social Sciences
2,022
34,991,674
AHSA1 is a promising therapeutic target for cellular proliferation and proteasome inhibitor resistance in multiple myeloma.
Journal of experimental clinical cancer research : CR
J Exp Clin Cancer Res
41
1
10.1186/s13046-021-02220-1
eng
2,022
1
6
2,022
1
6
[BACKGROUND] Currently, multiple myeloma (MM) is still an incurable plasma cell malignancy in urgent need of novel therapeutic targets and drugs. [METHODS] Bufalin was known as a highly toxic but effective anti-cancer compound. We used Bufalin as a probe to screen its potential targets by proteome microarray, in which ...
AHSA1; Bufalin; Drug resistance; HSP90; KU-177; Multiple myeloma; Proliferation; Proteasomal inhibitor
null
null
null
null
null
34,991,638
Translating Medicaid policy into practice: policy implementation strategies from three US states' experiences enhancing substance use disorder treatment.
Implementation science : IS
Implement Sci
17
1
10.1186/s13012-021-01182-4
eng
2,022
1
6
2,022
1
6
[BACKGROUND] Despite the important upstream impact policy has on population health outcomes, few studies in implementation science in health have examined implementation processes and strategies used to translate state and federal policies into accessible services in the community. This study examines the policy implem...
Health policy; Implementation science; Medicaid; Policy implementation; Public policy; Qualitative; Substance use disorder
2.861
157
Health Informatics; Health Policy; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,022
34,991,506
Association of Covid-19 pandemic-related stress and depressive symptoms among international medical students.
BMC psychiatry
BMC Psychiatry
22
1
10.1186/s12888-021-03671-8
eng
2,022
1
7
2,022
1
7
[BACKGROUND] The outbreak of Covid-19 had negative impacts on the mental stress and induced psychological distress among university students worldwide. This study proposed a moderated mediation model, and hypothesized that the Covid-19 pandemic-related stress was positively related to depressive symptoms among internat...
Coping style; Covid-19; Depressive symptoms; Perceived social support; Stress
1.291
151
Psychiatry and Mental Health
Medicine
2,022
34,991,354
Six-Strand Flexor Pollicis Longus Tendon Repairs With and Without Circumferential Sutures: A Multicenter Study.
Hand (New York, N.Y.)
Hand (N Y)
18
5
10.1177/15589447211057295
eng
2,023
7
null
2,022
1
7
[BACKGROUND] The purpose of this study is to assess outcomes in flexor pollicis longus tendon repairs with 6-strand core sutures with and without circumferential sutures. [METHODS] A 6-strand core suture technique with and without circumferential sutures was used. Thirty-three patients were summarized in the C group (c...
circumferential suture; early active motion; flexor pollicis longus tendon; primary flexor tendon repair; without circumferential suture
0.715
50
Surgery; Orthopedics and Sports Medicine
Medicine
2,023
34,991,248
Marine pollutant exposures and human milk extracellular vesicle-microRNAs in a mother-infant cohort from the Faroe Islands.
Environment international
Environ Int
158
null
10.1016/j.envint.2021.106986
eng
2,022
1
null
2,021
11
20
[BACKGROUND/AIMS] Early life exposures to marine contaminants can adversely impact child health but modes of action are unclear. Human milk contains extracellular vesicles (EVs) that can transport biologically relevant cargo from mother to infant, including microRNAs (miRNAs), and may partly mediate the effects of poll...
Extracellular vesicles; Mercury; Perfluoroalkyl substances; Persistent organic pollutants; microRNA
3.075
274
Environmental Science
Environmental Science
2,022
34,991,199
Elevated thyroid hormones caused by high concentrate diets participate in hepatic metabolic disorders in dairy cows.
Animal bioscience
Anim Biosci
35
8
10.5713/ab.21.0397
eng
2,022
8
null
2,022
1
5
[OBJECTIVE] High concentrate diets are widely used to satisfy high-yielding dairy cows; however, long-term feeding of high concentrate diets can cause subacute ruminal acidosis (SARA). The endocrine disturbance is one of the important reasons for metabolic disorders caused by SARA. However, there is no current report a...
Glucose Metabolism; High Concentrate Diets; Lactating Dairy Cows; Lipid Metabolism; Thyroid Hormones
0.613
89
Animal Science and Zoology; Veterinary; Food Science; Genetics; Physiology
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Veterinary
2,022
34,991,137
Agreement Between Peak Inspiratory Pressure in Decelerating-Flow Ventilation and Plateau Pressure in Square-Flow Ventilation in Pediatric Acute Respiratory Distress Syndrome.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Pediatr Crit Care Med
23
3
10.1097/PCC.0000000000002884
eng
2,022
3
1
null
null
null
[OBJECTIVES] Acute respiratory distress syndrome guidelines suggest limiting plateau pressures to 28-30 cm H2O. Plateau pressure is most accurately measured in square-flow modes, such as volume control. In children, decelerating-flow modes, such as pressure-regulated volume control and pressure control, are more common...
null
1.42
111
Critical Care and Intensive Care Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,022
34,991,110
Association of Medicaid Expansion Under the Affordable Care Act With Perinatal Care Access and Utilization Among Low-Income Women: A Systematic Review and Meta-analysis.
Obstetrics and gynecology
Obstet Gynecol
139
2
10.1097/AOG.0000000000004647
eng
2,022
2
1
null
null
null
[OBJECTIVE] To synthesize the empirical research evidence about the association between Medicaid expansion under the Affordable Care Act (ACA) and increasing perinatal care access and utilization among low-income women. [DATA SOURCES] We searched MEDLINE through PubMed (1966-present), EMBASE (Ovid), the Cumulative Inde...
null
2.48
268
Obstetrics and Gynecology
Medicine
2,022
34,991,059
Role of immune mediators in predicting hospitalization of SARS-CoV-2 positive patients.
Cytokine
Cytokine
150
null
10.1016/j.cyto.2021.155790
eng
2,022
2
null
2,021
12
25
[BACKGROUND] Several immune mediators (IM) including cytokines, chemokines, and their receptors have been suggested to play a role in COVID-19 pathophysiology and severity. [AIM] To determine if early IM profiles are predictive of clinical outcome and which of the IMs tested possess the most clinical utility. [METHODS]...
COVID-19; Hospitalization; IL-6; Immune mediator; Multiplex assay; SARS-CoV-2
0.897
142
Biochemistry; Hematology; Immunology; Immunology and Allergy; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,022
34,990,899
Reiki practitioners' perceptions of the impact of the COVID-19 pandemic on the experience, practice and future of Reiki.
Complementary therapies in clinical practice
Complement Ther Clin Pract
46
null
10.1016/j.ctcp.2021.101530
eng
2,022
2
null
2,021
12
30
[OBJECTIVES] This study examined the impact of the COVID-19 pandemic on the experience, practice and future of Reiki in the UK, including the personal impact of the pandemic on practitioners and their work, practitioner perceptions of the future of the profession and Reiki delivery, and practitioner experiences and vie...
COVID-19 pandemic; Practice; Reiki
0.664
67
Complementary and Alternative Medicine
Medicine
2,022
34,989,654
The societal economic value of COVID-19 vaccines in the United States.
Journal of medical economics
J Med Econ
25
1
10.1080/13696998.2022.2026118
eng
2,022
null
null
null
null
null
[AIMS] The COVID-19 pandemic has claimed the lives of more than 800,000 people in the United States (US) and has been estimated to carry a societal cost of $16 trillion over the next decade. The availability of COVID-19 vaccines has had a profound effect on the trajectory of the pandemic, with wide-ranging benefits. We...
COVID-19; H; H5; H51; I; I1; I10; I18; cases avoided; coronavirus; life years saved; pandemic; societal value; vaccine
0.74
58
Health Policy
Medicine
2,022
34,989,342
Inpatient Early Intervention for Serious Mental Illnesses Is Associated With Fewer Rehospitalizations Compared With Treatment as Usual in a High-volume Public Psychiatric Hospital Setting.
Journal of psychiatric practice
J Psychiatr Pract
28
1
10.1097/PRA.0000000000000596
eng
2,022
1
6
2,022
1
6
[OBJECTIVE] High-acuity publicly funded inpatient psychiatric settings usually feature short lengths of stay and high readmission rates. This study examined the influence of an early intervention program for serious mental illnesses (SMI) on readmissions at 6 and 12 months postdischarge at a high-volume, urban public i...
null
0.413
63
Psychiatry and Mental Health
Medicine
2,022
34,989,297
Rate and predictors of 30-day readmission for clostridiodes difficile: a United States analysis.
Annals of medicine
Ann Med
54
1
10.1080/07853890.2021.2023211
eng
2,022
12
null
null
null
null
[BACKGROUND] Clostridiodes difficile is a leading cause of healthcare-associated diarrhea. In this study, we aimed to identify the rates and predictors for 30-day readmissions of Clostridiodes difficile Enterocolitis (CDE) in the United States. [METHODS] We conducted a retrospective study of the Nationwide Readmissions...
Clostridiodes difficile Enterocolitis; epidemiology predictors; mortality costs; readmission
1.052
133
Medicine
Medicine
2,022
34,989,044
The status and associated factors of junior nurses' transition shock: A cross-sectional study.
Journal of nursing management
J Nurs Manag
30
3
10.1111/jonm.13543
eng
2,022
4
null
2,022
1
17
[AIM] To analyse junior nurses['] transition shock status and its associated factors. [BACKGROUND] When nurses experience transition shock, turnover intentions followed by turnover behaviour are likely, which is unfavourable for the stable development of nursing teams. [METHODS] Using convenience sampling, 1,148 Chines...
feedback seeking; humanistic care; nurses; transition shock
1.341
103
Leadership and Management
Nursing
2,022
34,988,344
Different Electrophysiological Responses to Pain-Related Visual Stimuli Between Fibromyalgia and Chronic low Back Pain Women: A Pilot Case-Control Study.
Chronic stress (Thousand Oaks, Calif.)
Chronic Stress (Thousand Oaks)
5
null
10.1177/24705470211046881
eng
2,021
null
null
2,021
12
2
[BACKGROUND] Fibromyalgia is a chronic pain syndrome which occurs in the absence of an organic damage, whom causes is still unclear. Aims of this pilot study were to investigate the neural correlates of fibromyalgia in response to pain-related visual stimuli and explore the psychological differences among fibromyalgia,...
ERP; chronic low back pain; fibromyalgia; neural correlates; sLORETA
null
null
null
null
null
34,988,330
Permanent pacemaker post-valve surgery: Do valve type and position matter? A propensity score matching study.
Journal of clinical and translational research
J Clin Transl Res
7
6
null
eng
2,021
12
28
2,021
11
29
[BACKGROUND AND AIM] This study evaluates whether aortic valve replacement (AVR) or mitral valve replacement (MVR) with biological versus mechanical prostheses is independent risk factors for permanent pacemaker (PPM) post-cardiac surgery, alongside traditionally accepted determinants. [METHODS] This study focused on s...
mitral valve; pacemaker; valve surgery
null
null
null
null
null
34,988,237
ACL Size, but Not Signal Intensity, Is Influenced by Sex, Body Size, and Knee Anatomy.
Orthopaedic journal of sports medicine
Orthop J Sports Med
9
12
10.1177/23259671211063836
eng
2,021
12
null
2,021
12
17
[BACKGROUND] Little is known about sex-based differences in anterior cruciate ligament (ACL) tissue quality in vivo or the association of ACL size (ie, volume) and tissue quality (ie, normalized signal intensity on magnetic resonance imaging [MRI]) with knee anatomy. [HYPOTHESIS] We hypothesized that (1) women have sma...
ACL; anatomy; sex differences; signal intensity
1.037
68
Orthopedics and Sports Medicine
Medicine
2,021
34,988,209
A multicenter single-arm trial of sintilimab in combination with chemotherapy for neoadjuvant treatment of resectable esophageal cancer (SIN-ICE study).
Annals of translational medicine
Ann Transl Med
9
22
10.21037/atm-21-6102
eng
2,021
11
null
null
null
null
[BACKGROUND] Preoperative chemotherapy or chemoradiotherapy is the standard treatment for resectable esophageal cancer (EC); however, it is associated with increased postoperative complications and mortality. Recently, Immune Checkpoint inhibitors have been incorporated in the treatment of advanced EC. Its role in the ...
Sintilimab; efficacy; major pathological response (MPR); pathological complete response (pCR); safety
null
null
null
null
null
34,988,208
Effect of cigarette smoke extract on mitochondrial division in mouse quadriceps femoris cells.
Annals of translational medicine
Ann Transl Med
9
22
10.21037/atm-21-5891
eng
2,021
11
null
null
null
null
[BACKGROUND] To observe the effect of cigarette smoke extract (CSE) on mitochondrial division in mouse quadriceps femoris cells and to explore the potential molecular mechanism of skeletal muscle dysfunction (SMD) in patients with chronic obstructive pulmonary disease (COPD). [METHODS] Quadriceps femoris were cultured,...
Chronic obstructive pulmonary disease (COPD); Dynamin related protein 1 (Drp-1); cigarette smoke extract (CSE); quadriceps femoris
null
null
null
null
null
34,987,714
Comparison of condylar position in normal occlusion, Class II Division 1, Class II Division 2 and Class III malocclusions using CBCT imaging.
Journal of clinical and experimental dentistry
J Clin Exp Dent
13
12
10.4317/jced.58970
eng
2,021
12
null
2,021
12
1
[BACKGROUND] The aim of this study was to establish the condylar position in a group of patients with normal occlusion, compared to Class II Div 1, Class II Div 2 and Class III malocclusions using CBCT imaging. [MATERIAL AND METHODS] Retrospective case-control study carried out by analyzing CBCT images of 80 patients. ...
null
0.403
44
Dentistry
Dentistry
2,021
34,987,344
Transition practice before entering primary school: A longitudinal study of children with and without special needs across a year.
Hong Kong journal of occupational therapy : HKJOT
Hong Kong J Occup Ther
34
2
10.1177/15691861211013427
eng
2,021
12
null
2,021
5
18
[INTRODUCTION] The transition to primary school is a significant milestone for children. Transition periods can offer new opportunities to build skills, relationships, and experiences that strengthen self-efficacy. In Singapore, parents play an important role in supporting transition as preschools and primary schools o...
Occupational therapy; early childhood; parent interview; school readiness; strategies
0.21
22
Occupational Therapy
Health Professions
2,021
34,987,195
Preliminary clinical validation of a new picture-based visual acuity test in children with amblyopia: a comparison of The Auckland Optotypes and crowded logMAR letters.
Eye (London, England)
Eye (Lond)
36
12
10.1038/s41433-021-01840-3
eng
2,022
12
null
2,022
1
6
[BACKGROUND/AIMS] Amblyopia is the most common visual deficit in children and accurate visual acuity (VA) assessment is essential for diagnosis. While ETDRS high-contrast logMAR VA is the reference standard test for adults, less agreement exists for pre-literate children. A new picture optotype acuity test (The Aucklan...
null
null
null
null
null
null
34,986,918
Impact of fetal haemodynamics on surgical and neurodevelopmental outcomes in patients with Ebstein anomaly and tricuspid valve dysplasia.
Cardiology in the young
Cardiol Young
32
11
10.1017/S1047951121004935
eng
2,022
11
null
2,022
1
6
[OBJECTIVES] To evaluate the impact of fetal haemodynamics on surgical and neurodevelopmental outcomes in severe Ebstein anomaly and tricuspid valve dysplasia. [METHODS] Thirty-four fetuses with Ebstein anomaly/tricuspid valve dysplasia were referred from 2013 to 2019 for fetal echocardiography and clinical management....
Ebstein anomaly; Fetal haemodynamics; neurodevelopment
0.387
68
Cardiology and Cardiovascular Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,022
34,986,909
Does a prenatal diagnosis affect mortality and morbidity for neonatal arterial switch operation.
Cardiology in the young
Cardiol Young
32
10
10.1017/S1047951121004819
eng
2,022
10
null
2,022
1
6
[BACKGROUND] The effect of prenatal diagnosis on prognosis in patients with transposition of the great arteries is not clear. In this study, we compared the outcomes after arterial switch operation. [METHODS] Outcome of 112 patients who had arterial switch operation in the neonatal period were analysed. The patients we...
Arterial switch operation; newborn; prenatal diagnosis; transposition of great arteries
0.387
68
Cardiology and Cardiovascular Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,022
34,986,892
The risk of malignancy in patients with IgG4-related disease: a systematic review and meta-analysis.
Arthritis research therapy
Arthritis Res Ther
24
1
10.1186/s13075-021-02652-2
eng
2,022
1
5
2,022
1
5
[BACKGROUND] The relationship between IgG4-related disease (IgG4-RD) and the risk of malignancy is still controversial. This article focused on assessing the risk of cancer in patients with IgG4-RD by meta-analysis. [METHODS] We conducted a systematic review of the literature and meta-analysis characterizing the associ...
IgG4-RD; Malignancy; Meta-analysis; SIR
null
null
null
null
null
34,986,876
Neddylation-dependent protein degradation is a nexus between synaptic insulin resistance, neuroinflammation and Alzheimer's disease.
Translational neurodegeneration
Transl Neurodegener
11
1
10.1186/s40035-021-00277-8
eng
2,022
1
6
2,022
1
6
[BACKGROUND] The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease. It has been proposed that neuroinflammation might be an intervening variable, but ...
Alzheimer's disease; Cullins; IRS1; Insulin; MLN-4924; Metabolic syndrome; Neddylation
2.571
67
Cellular and Molecular Neuroscience; Cognitive Neuroscience; Neurology
Medicine; Neuroscience
2,022
34,986,688
The use of AVF.SIM system for the surgical planning of arteriovenous fistulae in routine clinical practice.
The journal of vascular access
J Vasc Access
24
5
10.1177/11297298211062695
eng
2,023
9
null
2,022
1
6
[BACKGROUND] The number of patients treated with hemodialysis (HD) in Europe is more than half a million and this number increases annually. The arteriovenous fistula (AVF) is the vascular access (VA) of first choice, but the clinical outcome is still poor. A consistent number of AVFs fails to reach the desired blood f...
Arteriovenous fistula; computational modeling; hemodialysis; surgical planning; vascular access
0.463
51
Nephrology; Surgery
Medicine
2,023
34,986,670
Cardioprotective effects of alantolactone on isoproterenol-induced cardiac injury and cobalt chloride-induced cardiomyocyte injury.
International journal of immunopathology and pharmacology
Int J Immunopathol Pharmacol
36
null
10.1177/20587384211051993
eng
2,022
null
null
null
null
null
[OBJECTIVES] Alantolactone (AL) is a compound extracted from the roots of Inula Racemosa that has shown beneficial effects in cardiovascular disease. However, the cardioprotective mechanism of AL against hypoxic/ischemic (H/I) injury is still unclear. This research aimed to determine AL's ability to protect the heart a...
L-type calcium channel currents; alantolactone; calcium influx; cardio-protection; oxidative stress
null
null
null
null
null
34,986,557
Serial Multiple Mediation of the Correlation Between Internet Addiction and Depression by Social Support and Sleep Quality of College Students During the COVID-19 Epidemic.
Psychiatry investigation
Psychiatry Investig
19
1
10.30773/pi.2021.0147
eng
2,022
1
null
2,022
1
7
[OBJECTIVE] This cross-sectional study explores the serial multiple mediation of the correlation between internet addiction and depression by social support and sleep quality of college students during the COVID-19 epidemic. [METHODS] We enrolled 2,688 students from a certain university in Wuhu, China. Questionnaire me...
Addictive disorder; Depressive disorder; Epidemiology; Sleep disorder
0.716
57
Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience
2,022
34,986,555
A New Acute-At-Home Child and Adolescent Clinical Service: Evaluation of Impact.
Psychiatry investigation
Psychiatry Investig
19
1
10.30773/pi.2021.0158
eng
2,022
1
null
2,022
1
7
[OBJECTIVE] An Acute at Home (AAH) clinical service was implemented to reduce emergency and inpatient admissions to the regional tertiary child and adolescent mental health system. This paper examines describes the served the population and impact on emergency and inpatient admissions. [METHODS] Analysis of re-admissio...
Acute at home; Adolescent; Adverse childhood experience; Child; Measureable treatment plan; Mental health; Shaping demand
0.716
57
Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience
2,022
34,986,374
Socioeconomic status, alcohol use disorders, and depression: A population-based study.
Journal of affective disorders
J Affect Disord
301
null
10.1016/j.jad.2021.12.132
eng
2,022
3
15
2,022
1
2
[BACKGROUND] Depressive disorders (DD) and alcohol use disorders (AUD) frequently co-occur. They are key to understanding the current increases in "deaths of despair" among individuals with lower socioeconomic status (SES). The aim of this study was to assess the prospective bidirectional associations between AUD and D...
Alcohol consumption; Cohort; Depressive disorders; Educational attainment; General population; Interaction; Severity of mental disorders
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
34,985,733
Better intraoperative cardiopulmonary stability and similar postoperative results of spontaneous ventilation combined with intubation than non-intubated thoracic surgery.
General thoracic and cardiovascular surgery
Gen Thorac Cardiovasc Surg
70
6
10.1007/s11748-021-01768-1
eng
2,022
6
null
2,022
1
5
[OBJECTIVES] Non-intubated spontaneous ventilation video-assisted thoracic surgery lobectomy is a well-known procedure, but there are doubts regarding its safety. To solve this problem, we developed a safe procedure for spontaneous ventilation thoracic surgery (spontaneous ventilation with intubation). This study analy...
Intubation; Non-intubated; Spontaneous ventilation; Video-assisted thoracic surgery
0.481
50
Surgery; Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022