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35,211,300
Establishing a core outcome measure for pain in patients with autosomal dominant polycystic kidney disease: a consensus workshop report.
Clinical kidney journal
Clin Kidney J
15
3
10.1093/ckj/sfab110
eng
2,022
3
null
2,021
7
6
[BACKGROUND] Pain is the highest prioritized patient-reported outcome in people with autosomal dominant polycystic kidney disease (ADPKD) but remains infrequently and inconsistently measured in clinical trials and poorly managed in clinical settings. A recently completed systematic review of pain in ADPKD identified 26...
ADPKD; measure; pain; patient-reported outcomes; workshop
1.079
69
Nephrology; Transplantation
Medicine
2,022
35,210,953
An Overview of Play Therapy.
Materia socio-medica
Mater Sociomed
33
4
10.5455/msm.2021.33.293-297
eng
2,021
12
null
null
null
null
[BACKGROUND] Play is an essential parameter of children's growth and expression and this is the reason of why the use of play therapy is considered as fundamental means of preventing and dealing with problems and difficulties presented to children. [OBJECTIVE] The aim of this paper is to review the parameters related t...
child and adolescent therapy; children; mental health; pediatric nursing; play therapy
null
14
Economics, Econometrics and Finance; Social Sciences
Economics, Econometrics and Finance; Social Sciences
2,021
35,210,837
LINC01006 and miR-3199 Serve as Novel Markers of Poor Prognosis in Colon Cancer and Regulate Cell Proliferation, Migration and Invasion.
International journal of general medicine
Int J Gen Med
15
null
10.2147/IJGM.S334701
eng
2,022
null
null
2,022
2
16
[PURPOSE] Colon cancer is the most commonly diagnosed gastrointestinal cancer. This research intended to evaluate the prognostic values of LINC01006 and miR-3199 for colon cancer and their effects on cell physiology. [PATIENTS AND METHODS] LINC01006 and miR-3199 expression levels were determined by RT-qPCR. Patients' 5...
LINC01006; colon cancer; miR-3199; prognosis
null
null
null
null
null
35,210,793
Dietary Advanced Glycation End Products Shift the Gut Microbiota Composition and Induce Insulin Resistance in Mice.
Diabetes, metabolic syndrome and obesity : targets and therapy
Diabetes Metab Syndr Obes
15
null
10.2147/DMSO.S346411
eng
2,022
null
null
2,022
2
15
[OBJECTIVE] This study aimed to explore the associations between gut microbiota characteristics and glycometabolic profiles in mice fed diets high in advanced glycation end products (AGEs). [METHODS] C57BL/6 mice were exposed to a heat-treated diet or exogenous AGEs for 24 weeks, and glucose metabolism was assessed via...
advanced glycation end products; diet; gut microbiota; insulin resistance
0.851
71
Internal Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,210,788
Clinical Validation of the Spirohome Clinic Ultrasonic Spirometer in Child and Adolescent Patients.
Journal of asthma and allergy
J Asthma Allergy
15
null
10.2147/JAA.S345189
eng
2,022
null
null
2,022
2
15
[BACKGROUND] Spirometers are critical devices that reveal the respiratory dynamics caused by respiratory problems and their severity and facilitate their diagnosis and follow-up. Hand-held spirometers have emerged relatively recently and offer several advantages over conventional desktop systems. There remains, however...
FEV1; FVC; handheld spirometer; pediatric; portable spirometer; respiratory disease; spirometry; ultrasonic spirometer
0.801
45
Immunology and Allergy; Pulmonary and Respiratory Medicine
Medicine
2,022
35,210,714
Psoas muscle size, possible sarcopenia and frailty, and long-term survival in elderly patients after isolated surgical aortic valve replacement for aortic stenosis.
Indian journal of thoracic and cardiovascular surgery
Indian J Thorac Cardiovasc Surg
38
2
10.1007/s12055-021-01253-7
eng
2,022
3
null
2,022
2
2
[PURPOSE] This study investigated the use of psoas muscle area index (PAI) as an indicator of mortality risk in relation to survival in elderly patients after isolated surgical aortic valve replacement (SAVR) for aortic valve stenosis (AS). [METHODS] Between January 2005 and March 2015, 140 patients with AS, aged ≥ 70 ...
Aortic valve stenosis; Elderly; Isolated surgical aortic valve replacement; Psoas muscles; Sarcopenia
0.243
16
Cardiology and Cardiovascular Medicine; Surgery; Pulmonary and Respiratory Medicine
Medicine
2,022
35,210,330
Recent trends in high-volume Medicare stroke thrombectomy provider characteristics.
Journal of neurointerventional surgery
J Neurointerv Surg
15
4
10.1136/neurintsurg-2021-018611
eng
2,023
4
null
2,022
2
24
[BACKGROUND] Intracranial mechanical thrombectomy (MT) is increasingly indicated for use in acute ischemic stroke patients. We analyzed recent trends in the characteristics and geographic distributions of physicians providing this service with frequency to Medicare beneficiaries. [METHODS] We linked public data sources...
economics; stroke; thrombectomy
1.659
90
Medicine; Neurology; Surgery
Medicine
2,023
35,209,961
Altered prefrontal activation during the inhibition of eating responses in women with bulimia nervosa.
Psychological medicine
Psychol Med
53
8
10.1017/S0033291722000198
eng
2,023
6
null
2,022
2
25
[BACKGROUND] The sense of 'loss of control' (LOC), or a feeling of being unable to stop eating or control what or how much one is eating, is the most salient aspect of binge eating. However, the neural alterations that may contribute to this experience and eating behavior remain poorly understood. [METHODS] We used fun...
Bulimia nervosa; fNIRS; inhibitory control; loss-of-control eating; prefrontal cortex
2.768
251
Applied Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,023
35,209,943
Long-term effect of epigenetic modification in plant-microbe interactions: modification of DNA methylation induced by plant growth-promoting bacteria mediates promotion process.
Microbiome
Microbiome
10
1
10.1186/s40168-022-01236-9
eng
2,022
2
24
2,022
2
24
[BACKGROUND] Soil microbiomes are considered a cornerstone of the next green revolution, and plant growth-promoting bacteria (PGPB) are critical for microbiome engineering. However, taking plant-beneficial microorganisms from discovery to agricultural application remains challenging, as the mechanisms underlying the in...
DNA methylation; Epigenetic modification; Microbiome engineering; Plant growth-promoting bacteria; Rhizosphere microbiome
3.709
163
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,022
35,209,940
Therapeutic efficacy of mesenchymal stem cells for abdominal aortic aneurysm: a meta-analysis of preclinical studies.
Stem cell research therapy
Stem Cell Res Ther
13
1
10.1186/s13287-022-02755-w
eng
2,022
2
24
2,022
2
24
[BACKGROUND] Abdominal aortic aneurysm (AAA) is life-threatening, surgical treatment is currently the only clinically available intervention for the disease. Mesenchymal stem cells (MSCs) have presented eligible immunomodulatory and regenerative abilities which showed favorable therapeutic efficacy in various cardiovas...
Abdominal aortic aneurysm; Cell therapy; Mesenchymal stem cell; Meta-analysis; Preclinical studies
null
null
null
null
null
35,204,037
Dimensions of Tinnitus-Related Distress.
Brain sciences
Brain Sci
12
2
10.3390/brainsci12020275
eng
2,022
2
16
2,022
2
16
[OBJECTIVES] (1) To determine which psychosocial aspects predict tinnitus-related distress in a large self-reported dataset of patients with chronic tinnitus, and (2) to identify underlying constructs by means of factor analysis. [METHODS] A cohort of 1958 patients of the Charité Tinnitus Center, Berlin completed a lar...
comorbidity; factor analysis; predictors; psychological stress; tinnitus
0.752
78
Neuroscience
Neuroscience
2,022
35,204,026
A Social Business Model of Early Intervention and Rehabilitation for People with Disability in Rural Bangladesh.
Brain sciences
Brain Sci
12
2
10.3390/brainsci12020264
eng
2,022
2
14
2,022
2
14
[BACKGROUND] Despite the high burden of childhood disability in low-and middle-income countries (LMICs), the opportunity for early intervention and rehabilitation is very limited. Studies have found that community-based rehabilitation service is effective for children with cerebral palsy (CP); however, such services ar...
cerebral palsy; community-based rehabilitation; disability; early intervention; rehabilitation; social business model; sustainability
0.752
78
Neuroscience
Neuroscience
2,022
35,203,376
Characterization of Collapsin Response Mediator Protein 2 in Colorectal Cancer Progression in Subjects with Diabetic Comorbidity.
Cells
Cells
11
4
10.3390/cells11040727
eng
2,022
2
18
2,022
2
18
[BACKGROUND] Common demographic risk factors are identified in colorectal cancer (CRC) and type 2 diabetes mellitus (DM), nevertheless, the molecular link and mechanism for CRC-DM comorbidity remain elusive. Dysregulated glycogen synthase kinase-3 beta under metabolic imbalance is suggested to accelerate CRC pathogenes...
CRMP2; colorectal cancer; hyperglycemia; type 2 diabetes mellitus
1.537
158
Biochemistry, Genetics and Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,022
35,203,362
S1P Signalling Axis Is Necessary for Adiponectin-Directed Regulation of Electrophysiological Properties and Oxidative Metabolism in C2C12 Myotubes.
Cells
Cells
11
4
10.3390/cells11040713
eng
2,022
2
17
2,022
2
17
[BACKGROUND] Adiponectin (Adn), released by adipocytes and other cell types such as skeletal muscle, has insulin-sensitizing and anti-inflammatory properties. Sphingosine 1-phosphate (S1P) is reported to act as effector of diverse biological actions of Adn in different tissues. S1P is a bioactive sphingolipid synthesiz...
NMR metabolomics; S1P receptors; adiponectin; electrophysiological properties; oxygen consumption; skeletal muscle; sphingosine 1-phosphate; sphingosine kinase
1.537
158
Biochemistry, Genetics and Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,022
35,203,101
Physicochemical property evaluation of modified oligonucleotides by traveling-wave ion mobility mass spectrometry.
Rapid communications in mass spectrometry : RCM
Rapid Commun Mass Spectrom
36
10
10.1002/rcm.9279
eng
2,022
5
30
null
null
null
[RATIONALE] Therapeutic oligonucleotides have molecular weights of more than 6000 Da. They typically contain chemically modified structures such as phosphorothioate (PS) and a locked nucleic acid (LNA). To determine the effect of the length and chemical modification on the physicochemical properties, various nucleic ac...
null
0.423
152
Analytical Chemistry; Organic Chemistry; Spectroscopy
Chemistry
2,022
35,202,954
Recommendations for a practical implementation of circulating tumor DNA mutation testing in metastatic non-small-cell lung cancer.
ESMO open
ESMO Open
7
2
10.1016/j.esmoop.2022.100399
eng
2,022
4
null
2,022
2
21
[BACKGROUND] Liquid biopsy (LB) is a rapidly evolving diagnostic tool for precision oncology that has recently found its way into routine practice as an adjunct to tissue biopsy (TB). The concept of LB refers to any tumor-derived material, such as circulating tumor DNA (ctDNA) or circulating tumor cells that are detect...
ctDNA mutation testing; non-small-cell lung cancer; patient scenario; precision oncology
2.196
70
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,202,042
Artificial Neural Networks Can Predict Early Failure of Cementless Total Hip Arthroplasty in Patients With Osteoporosis.
The Journal of the American Academy of Orthopaedic Surgeons
J Am Acad Orthop Surg
30
10
10.5435/JAAOS-D-21-00775
eng
2,022
5
15
2,022
2
23
[BACKGROUND] Total hip arthroplasty (THA) done in the aging population is associated with osteoporosis-related complications. The altered bone density in osteoporotic patients is a risk factor for revision surgery. This study aimed to develop and validate machine learning (ML) models to predict revision surgery in pati...
null
1.323
145
Medicine; Orthopedics and Sports Medicine; Surgery
Medicine
2,022
35,201,836
Moral injury appraisals in young people from refugee backgrounds in Melbourne, Australia.
Psychological trauma : theory, research, practice and policy
Psychol Trauma
15
1
10.1037/tra0001214
eng
2,023
1
null
2,022
2
24
[OBJECTIVE] While moral injury can influence psychological outcomes experienced by adult refugees, no research to date has examined moral injury among young refugees. This study aimed to investigate the associations between moral injury and mental health in young people with refugee backgrounds. [METHOD] Participants w...
null
1.552
86
Clinical Psychology; Social Psychology
Psychology
2,023
35,201,460
Upregulation of TCF21 inhibits migration of adrenocortical carcinoma cells.
Discover oncology
Discov Oncol
12
1
10.1007/s12672-021-00417-6
eng
2,021
7
23
2,021
7
23
[BACKGROUND] Adrenocortical carcinomas (ACC) are rare and aggressive cancer. Our previous study has revealed that the transcription factor 21, TCF21, is downregulated in ACC and regulates steroidogenic factor 1 (SF-1) binding to the SF-1 E-box promoter. In addition, it could be found that TCF21 is a predictor of overal...
Adrenocortical carcinoma cells; Matrix metalloproteinases; Methylation; Migration; TCF21
null
47
Cancer Research; Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,021
35,200,249
Digital Dental Models: Is Photogrammetry an Alternative to Dental Extraoral and Intraoral Scanners?
Dentistry journal
Dent J (Basel)
10
2
10.3390/dj10020024
eng
2,022
2
7
2,022
2
7
[BACKGROUND] 3D models are nowadays part of daily clinical practice. Photogrammetry is a brand-new method for transforming small objects into 3D models while keeping their original shape and size. The aim of this study was to evaluate the accuracy, in terms of precision and trueness, of a digital dental model acquired ...
dental extraoral laboratory scanner; digital dental model; digital dentistry; intraoral scanner; photogrammetry; volumetric analysis
0.536
41
Dentistry
Dentistry
2,022
35,200,217
Prolonged Brace Treatment Does Not Result in Improved Acetabular Indices in Infantile Dislocated Hips.
Journal of pediatric orthopedics
J Pediatr Orthop
42
5
10.1097/BPO.0000000000002110
eng
null
null
null
null
null
null
[BACKGROUND] The Pavlik harness (PH) is commonly used to treat infantile dislocated hips. However, significant variability exists in the duration of brace treatment after successful reduction of the dislocated hip. The purpose of this study was to evaluate the effect of prescribed time in brace on acetabular index (AI)...
null
null
null
null
null
null
35,199,772
Knowledge of Oral Cancer among Online Respondent General Dentists: A Cross-sectional Survey.
JNMA; journal of the Nepal Medical Association
JNMA J Nepal Med Assoc
59
243
10.31729/jnma.5651
eng
2,021
11
15
2,021
11
15
[INTRODUCTION] Oral cancer is a worldwide medical issue with expanding paces of occurrence and rising mortality rates. Oral cancer is the sixth most common cancer in Nepal with a prevalence of 4.6%. Examination of the oral cavity includes evaluating all teeth, supporting tissue, and surrounding oral tissue and recordin...
mortality; oral cancer; squamous cell carcinoma.
null
null
null
null
null
35,199,194
Relationship between erosive tooth wear and possible etiological factors among dental students.
Clinical oral investigations
Clin Oral Investig
26
5
10.1007/s00784-022-04425-w
eng
2,022
5
null
2,022
2
24
[OBJECTIVES] The aim of this study was to assess the relationship between erosive tooth wear (ETW) and possible etiological factors in a group of dental students. [MATERIALS AND METHODS] A total of 126 dental students from a public dental school were included in this study. A questionnaire was used to investigate the p...
Dental erosion; Dental students; Erosive tooth wear; Prevention and control; Questionnaire
0.91
108
Dentistry
Dentistry
2,022
35,198,588
Association of Yogurt and Dietary Supplements Containing Probiotic Consumption With All-Cause and Cause-Specific Mortality in US Adults: A Population-Based Cohort Study.
Frontiers in nutrition
Front Nutr
9
null
10.3389/fnut.2022.803076
eng
2,022
null
null
2,022
2
7
[BACKGROUND] Although probiotic intake had beneficial effects on several specific disorders, limited evidence was available about the benefits of probiotic intake in the general population. This study aimed to evaluate the relationship between yogurt (as a natural probiotic source) and dietary supplements containing pr...
NHANES; mortality; population; probiotic; yogurt
0.875
94
Food Science; Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Agricultural and Biological Sciences; Medicine; Nursing
2,022
35,198,505
Medical Device-related Counseling Practice and Barriers among Sudanese Pharmacists: A Questionnaire-Based Study.
Journal of research in pharmacy practice
J Res Pharm Pract
10
3
10.4103/jrpp.JRPP_21_32
eng
2,021
null
null
2,021
12
25
[OBJECTIVE] The aim of the present study was to assess medical devices-related counseling practice and barriers among pharmacists. [METHODS] This was a cross-sectional study conducted using a convenient sample of Sudanese pharmacists. An online-version survey was used to collect data. [FINDINGS] One hundred and thirty ...
Barriers to counseling; Sudanese population; counseling practices; medical devices; medical supply; pharmacists; questionnaire
0.758
1
Pharmacology, Toxicology and Pharmaceutics; Pharmacy; Pharmacology
Health Professions; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,018
35,257,059
Sickle Cell Trait and Kidney Disease in People of African Ancestry With HIV.
Kidney international reports
Kidney Int Rep
7
3
10.1016/j.ekir.2021.12.007
eng
2,022
3
null
2,021
12
13
[INTRODUCTION] Sickle cell trait (SCT) has been associated with chronic kidney disease (CKD) in African Americans, although evidence for its impact in Africans and people with HIV is currently lacking. We conducted a cross-sectional study investigating the association between SCT and kidney disease in people of African...
APOL1; Africa; HIV; SCT; kidney; sickle cell trait
1.173
61
Nephrology
Medicine
2,022
35,256,901
Application of Esmolol to Control Heart Rate and Artificial Intelligence Reconstruction Analysis for Rapid Zero-Cooperation Emergency Coronary CTA.
Journal of healthcare engineering
J Healthc Eng
2022
null
10.1155/2022/7363589
eng
2,022
null
null
2,022
2
26
[OBJECTIVE] To investigate a rapid and effective method for the examination of coronary CTA in emergency patients requiring coronary CTA examination, who have faster heart rate (≧80 bpm) or cannot cooperate with the examination due to the inability of breath holding at poor physical conditions. [METHODS] Before coronar...
null
0.404
69
Surgery; Biomedical Engineering; Biotechnology; Health Informatics
Biochemistry, Genetics and Molecular Biology; Engineering; Medicine
2,022
35,256,895
Elevated Thyroid Autoantibodies Aggravate Stroke Severity in Euthyroidism with Acute Ischemic Stroke.
Disease markers
Dis Markers
2022
null
10.1155/2022/8741058
eng
2,022
null
null
2,022
2
26
[INTRODUCTION] Studies have indicated that immune reactions contribute to endothelial dysfunction and atherosclerosis. It is unclear whether thyroid dysfunction or elevated thyroid autoantibodies are associated with atherosclerosis. Therefore, we investigated the influence of thyroid autoimmunity related to elevated th...
null
0.662
85
Biochemistry; Clinical Biochemistry; Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,256,486
FOCUS4 biomarker laboratories: from the benefits to the practical and logistical issues faced during 6 years of centralised testing.
Journal of clinical pathology
J Clin Pathol
76
8
10.1136/jclinpath-2022-208233
eng
2,023
8
null
2,022
3
7
[AIMS] FOCUS4 was a phase II/III umbrella trial, recruiting patients with advanced or metastatic colorectal cancer, between 2014 and 2020. Molecular profiling of patients' formalin-fixed, paraffin-embedded tumour blocks was undertaken at two centralised biomarker laboratories (Leeds and Cardiff), and the results fed di...
biomarkers, tumor; colorectal cancer; immunohistochemistry
0.934
158
Medicine; Pathology and Forensic Medicine
Medicine
2,023
35,256,437
Caring in the silences: why physicians and surgeons do not discuss emergency care and treatment planning with their patients - an analysis of hospital-based ethnographic case studies in England.
BMJ open
BMJ Open
12
3
10.1136/bmjopen-2020-046189
eng
2,022
3
7
2,022
3
7
[BACKGROUND] Despite increasing emphasis on integrating emergency care and treatment planning (ECTP) into routine medical practice, clinicians continue to delay or avoid ECTP conversations with patients. However, little is known about the clinical logics underlying barriers to ECTP conversations. [OBJECTIVE] This study...
palliative care; qualitative research; quality in health care
1.059
176
Medicine
Medicine
2,022
35,256,218
Application of the REVEAL risk score calculator 2.0 in the CHEST study.
Respiratory medicine
Respir Med
195
null
10.1016/j.rmed.2022.106783
eng
2,022
null
null
2,022
3
1
[BACKGROUND] Currently there are no risk assessment recommendations for chronic thromboembolic pulmonary hypertension (CTEPH). The Registry to Evaluate Early and Long-Term PAH Disease Management (REVEAL) risk score (RRS), developed for risk assessment in patients with pulmonary arterial hypertension, has previously pre...
CTEPH; Chronic thromboembolic pulmonary hypertension; Pulmonary hypertension; Riociguat; Risk assessment
1.334
145
Pulmonary and Respiratory Medicine
Medicine
2,022
35,256,198
Risk Factors for New-Onset Diabetes Mellitus After Heart Transplantation: A Nomogram Approach.
Transplantation proceedings
Transplant Proc
54
3
10.1016/j.transproceed.2022.01.030
eng
2,022
4
null
2,022
3
4
[BACKGROUND] New-onset diabetes mellitus after transplantation (NODAT) is a leading cause of morbidity and mortality after heart transplantation (HT), which still remains a clinical challenge. [METHODS] In this study, 522,708 follow-up records of HT were reviewed. After screening, 14,452 patients were analyzed when com...
null
0.316
93
Surgery; Transplantation
Medicine
2,022
35,256,156
Open versus laparoscopic surgery in the management of patients with gallbladder cancer: A systematic review and meta-analysis.
American journal of surgery
Am J Surg
224
1 Pt B
10.1016/j.amjsurg.2022.03.002
eng
2,022
7
null
2,022
3
3
[BACKGROUND] The aim of this meta-analysis was to assess the safety and efficacy of laparoscopic surgery when compared to open surgery in the management of gallbladder cancer. [METHODS] Ovid Cochrane Library, Medline, Embase, Epub, and Scopus were searched. A meta-analysis of selected studies was performed, and a subgr...
Cholecystectomy; Gallbladder cancer; Laparoscopic; Meta-analysis; Open
0.85
173
Surgery; Medicine
Medicine
2,022
35,255,880
The effect of barberry (Berberis integerrima) on lipid profile and systemic inflammation in subjects with cardiovascular risk factors: a randomized controlled trial.
BMC complementary medicine and therapies
BMC Complement Med Ther
22
1
10.1186/s12906-022-03539-8
eng
2,022
3
7
2,022
3
7
[BACKGROUND] Despite significant advances in the management of cardiovascular disease (CVDs), there is still a large burden of CVD in the world. The inclusion of functional foods in the diet may provide beneficial effects on CVD. Purple-black barberry due to its richness in anthocyanins and berberine has shown benefici...
Barberry; CVD; Inflammation; Lipid profile
0.688
123
Complementary and Alternative Medicine
Medicine
2,022
35,255,860
Past dynamics of HIV transmission among men who have sex with men in Montréal, Canada: a mathematical modeling study.
BMC infectious diseases
BMC Infect Dis
22
1
10.1186/s12879-022-07207-7
eng
2,022
3
7
2,022
3
7
[BACKGROUND] Gay, bisexual, and other men who have sex with men (gbMSM) experience disproportionate risks of HIV acquisition and transmission. In 2017, Montréal became the first Canadian Fast-Track City, setting the 2030 goal of zero new HIV infections. To inform local elimination efforts, we estimate the evolving role...
Agent-based model; HIV/AIDS; Mathematical modeling; Treatment and care cascade
1.055
137
Infectious Diseases
Medicine
2,022
35,255,827
Factors influencing fear of falling in community-dwelling older adults in Singapore: a cross-sectional study.
BMC geriatrics
BMC Geriatr
22
1
10.1186/s12877-022-02883-1
eng
2,022
3
7
2,022
3
7
[BACKGROUND] Fear of falling (FoF) has far-reaching implications including activity restriction, functional decline and reduced quality of life. It is a common consequence of falls but may be present even in non-fallers. This study aimed to determine the factors associated with FoF in a segment of Singapore's community...
Community; Falls; Fear of Falling; Frailty; Older adults
1.127
112
Geriatrics and Gerontology
Medicine
2,022
35,255,812
Long-term survival of a patient with liver metastases from clear cell gastric adenocarcinoma after multimodality treatment including interventional oncology techniques: case report.
BMC gastroenterology
BMC Gastroenterol
22
1
10.1186/s12876-022-02150-y
eng
2,022
3
7
2,022
3
7
[BACKGROUND] Gastric cancer (GC) is the fourth most common cancer and the third leading cancer-related cause of death worldwide since most patients are diagnosed at an advanced stage. The majority of GCs are adenocarcinomas (ACs), and the poorly characterized clear cell AC represents a unique subgroup of GCs and is an ...
Gastric cancer; Hepatic metastases; Interventional oncology; Liver resection; Multidisciplinary approach; Portal vein embolization; SIRT; TACE
0.759
99
Gastroenterology; Medicine
Medicine
2,022
35,255,785
Wedelolactone, a Component from Eclipta prostrata (L.) L., Inhibits the Proliferation and Migration of Head and Neck Squamous Cancer Cells through the AhR Pathway.
Current pharmaceutical biotechnology
Curr Pharm Biotechnol
23
15
10.2174/1389201023666220307110554
eng
2,022
null
null
null
null
null
[BACKGROUND] Ecliptae prostrata (L.) L. has been widely used in East Asia with reported biological activities, including anti-cancer properties. [OBJECTIVES] We aimed to investigate the effect of ethyl acetate extract of Ecliptae prostrata (L.) L. (EAE) and its component wedelolactone on the proliferation and migration...
AhR; CYP1A1; CYP1B1; Ecliptae prostrata (L.) L; Wedelolactone; head and neck squamous cancer cells
null
null
null
null
null
35,255,402
Intensive physiotherapy versus home-based exercise and custom-made orthotic insoles in patients with plantar fasciitis: Pilot study.
Foot (Edinburgh, Scotland)
Foot (Edinb)
51
null
10.1016/j.foot.2022.101906
eng
2,022
5
null
2,022
1
7
[BACKGROUND] This prospective pilot study assessed the feasibility of comparing intensive physiotherapy group (IPG), home-based exercise (HBEG) group, and insole group (IG) to find the most effective treatment program for plantar fasciitis. [METHODS] Thirty-nine individuals with plantar fasciitis were selected to parti...
Exercise; Orthotic insole; Plantar fasciitis; Strengthening; Stretching
0.373
46
Podiatry; Medicine; Orthopedics and Sports Medicine
Health Professions; Medicine
2,022
35,255,239
A correlation of thrombin generation assay and clot waveform analysis in patients on warfarin.
Hematology (Amsterdam, Netherlands)
Hematology
27
1
10.1080/16078454.2022.2043573
eng
2,022
12
null
null
null
null
[OBJECTIVES] Thrombin generation assays and activated partial thromboplastin time (aPTT)-based clot waveform analysis (CWA), are some examples of global coagulation assays. Each modality evaluates different aspects of the clot forming process to globally define haemostasis with exclusive measurement parameters. Data on...
Anticoagulants; blood coagulation tests; partial thromboplastin time; thrombin; warfarin
null
null
null
null
null
35,254,733
Soybean dose-response to 2,4-D and dicamba at vegetative and reproductive growth stages.
Pest management science
Pest Manag Sci
78
7
10.1002/ps.6863
eng
2,022
7
null
2,022
5
12
[BACKGROUND] Field experiments were conducted across multiple sites in 2012 and 2013 to describe sensitivity of soybean to 2,4-D (six doses) and dicamba (seven doses) at V3 and R1 growth stages. Further experiments were conducted under greenhouse conditions in 2017 and 2018 to compare soybean response to several dicamb...
auxin herbicides; dose response; hormesis; injury; yield prediction
null
null
null
null
null
35,254,562
Biomechanical and Musculoskeletal Measurements as Risk Factors for Running-Related Injury in Non-elite Runners: A Systematic Review and Meta-analysis of Prospective Studies.
Sports medicine - open
Sports Med Open
8
1
10.1186/s40798-022-00416-z
eng
2,022
3
7
2,022
3
7
[BACKGROUND] Running-related injury (RRI) is highly prevalent among recreational runners and is a key barrier to participation. Atypical lower limb alignment and mechanical function have been proposed to play a role in development of lower extremity injury. The purpose of this study was to investigate relationships bet...
Biomechanics; Meta-analysis; Risk factor; Running-related injury; Screening; Systematic review
1.538
54
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation
Health Professions; Medicine
2,022
35,254,526
FDG-PET/CT for oral focus assessment in head and neck cancer patients.
Clinical oral investigations
Clin Oral Investig
26
6
10.1007/s00784-022-04403-2
eng
2,022
6
null
2,022
3
7
[OBJECTIVES] To compare oral and maxillo-mandibular inflammatory foci on standard oral radiographs (OPT, periapical radiograph) with available fluorine-18-labelled fluoro-2-deoxy-D-glucose-positron emission tomography/computed tomography (FDG-PET/CT) data and to discuss whether additional metabolic information derived ...
Head and neck cancer; Oral focus; Panoramic radiography; Periapical radiography; Radiochemotherapy
0.91
108
Dentistry
Dentistry
2,022
35,254,477
Comprehensive analyses of prognostic biomarkers and immune infiltrates among histone lysine demethylases (KDMs) in hepatocellular carcinoma.
Cancer immunology, immunotherapy : CII
Cancer Immunol Immunother
71
10
10.1007/s00262-022-03167-8
eng
2,022
10
null
2,022
3
7
[BACKGROUND] Histone lysine demethylases (KDMs) are closely related to the occurrence and development of different tumors through epigenetic mechanisms. However, the prognosis and immune infiltration of KDMs in hepatocellular carcinoma (HCC) remain undefined. [METHODS] In the current study, we analyzed the expression o...
Hepatocellular carcinoma; Histone lysine demethylases; Immune infiltrates; Prognosis biomarker
1.663
142
Cancer Research; Immunology; Immunology and Allergy; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,022
35,254,391
Humanistic and Economic Burden of Conversion Therapy Among LGBTQ Youths in the United States.
JAMA pediatrics
JAMA Pediatr
176
5
10.1001/jamapediatrics.2022.0042
eng
2,022
5
1
null
null
null
[IMPORTANCE] Sexual orientation and gender identity change efforts (SOGICE), also called conversion therapy, is a discredited practice attempting to convert lesbian, gay, bisexual, transgender, queer, or questioning (LGBTQ) individuals to be heterosexual and/or cisgender. [OBJECTIVES] To identify and synthesize evidenc...
null
5.109
231
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,254,203
Interventions regarding physicians' sickness certification practice - a systematic literature review with meta-analyses.
Scandinavian journal of primary health care
Scand J Prim Health Care
40
1
10.1080/02813432.2022.2036420
eng
2,022
3
null
2,022
3
7
[OBJECTIVE] A variety of interventions aiming to influence physicians' sickness certification practice have been conducted, most are, however, not evaluated scientifically. The aim of this systematic literature review was to obtain updated knowledge about interventions regarding physicians' sickness certification pract...
Sick leave; delay due to the covid-19 situation); insurance medicine; intervention; meta-analysis; return to work; sickness certification; systematic review
0.738
63
Public Health, Environmental and Occupational Health
Medicine
2,022
35,253,778
PTEN-Induced Putative Kinase 1 Dysfunction Accelerates Synucleinopathy.
Journal of Parkinson's disease
J Parkinsons Dis
12
4
10.3233/JPD-213065
eng
2,022
null
null
null
null
null
[BACKGROUND] Mutations in PTEN-induced putative kinase 1 (PINK1) cause autosomal recessive Parkinson's disease (PD) and contribute to the risk of sporadic PD. However, the relationship between PD-related PINK1 mutations and alpha-synuclein (α-syn) aggregation-a main pathological component of PD-remains unexplored. [OBJ...
Alpha-synuclein; Inflammation; PTEN-induced putative kinase 1; Protein phosphatase 2A
1.325
75
Neurology; Cellular and Molecular Neuroscience
Medicine; Neuroscience
2,022
35,253,776
The Effect of a Structured Medication Review on Quality of Life in Parkinson's Disease.
Journal of Parkinson's disease
J Parkinsons Dis
12
4
10.3233/JPD-213021
eng
2,022
null
null
null
null
null
[BACKGROUND] Drug therapy is important for controlling symptoms in Parkinson's disease (PD). However, it often results in complex medication regimens and could easily lead to drug related problems (DRP), suboptimal adherence and reduced treatment efficacy. A structured medication review (SMR) could address these issues...
clinical trials; drug administration schedule; drug therapy; medication adherence; pharmacists; quality of life
1.325
75
Neurology; Cellular and Molecular Neuroscience
Medicine; Neuroscience
2,022
35,253,738
Nonhypovascular pancreatic ductal adenocarcinomas: CEUS imaging findings and differentiation from other types of solid pancreatic lesions.
Clinical hemorheology and microcirculation
Clin Hemorheol Microcirc
81
2
10.3233/CH-221397
eng
2,022
null
null
null
null
null
[OBJECTIVES] To observe and assess the diagnostic value of contrast-enhanced ultrasound (CEUS) in patients with iso-/hypervascular solid pancreatic lesions. [METHODS] 70 pancreatic lesions (all confirmed by surgery or biopsy pathology) that manifested iso-/hyperenhancement on CEUS were retrospectively studied from Janu...
Ultrasonography; contrast agent; pancreatic neoplasms; pancreatitis
null
null
null
null
null
35,253,714
Transition to the forced telework - a challenge for trade unions identified by the study on working life with COVID-19 in Latvia.
Work (Reading, Mass.)
Work
71
3
10.3233/WOR-211042
eng
2,022
null
null
null
null
null
[BACKGROUND] In general, companies with trade unions perform better in occupational health and safety, therefore, we assume that these companies should have performed better in transition to healthy and safe telework if compared with other companies. [OBJECTIVE] The objective of the study was to assess the role of comp...
Distance work; work from home; worker representation
null
null
null
null
null
35,253,639
Introduction to the Project for Strengthening the ASEAN Regional Capacity on Disaster Health Management (ARCH Project).
Prehospital and disaster medicine
Prehosp Disaster Med
37
S1
10.1017/S1049023X22000036
eng
2,022
2
null
null
null
null
[BACKGROUND] Southeast Asia is the second biggest region in the world in terms of the total number of natural disasters since 1900. Therefore, the Association of Southeast Asian Nations (ASEAN) initiated regional challenges toward strengthening regional collaboration for disaster prevention and response since the earth...
ARCH Project; ASEAN Coordination and Collaboration Mechanism; Capacity Development; Disaster Health Management; Emergency Medical Team (EMT)
0.477
62
Emergency Medicine; Emergency Nursing
Medicine; Nursing
2,022
35,253,459
Post-Operative Spinal Epidural Hematoma: Are We Discontinuing Aspirin Early Enough?
Global spine journal
Global Spine J
13
8
10.1177/21925682221079259
eng
2,023
10
null
2,022
3
5
[STUDY DESIGN] Retrospective cohort study. [OBJECTIVES] (1) To compare the risk of Spinal Epidural Hematoma (SEH) associated with specific pre-operative and post-operative anticoagulation (AC) and antiplatelet medications (APM). (2) To define the incidence of SEH and identify risk factors for SEH in our population. [ME...
anticoagulation; antiplatelet; aspirin; complication; decompression; drain; fusion; hypertension; spinal epidural hematoma; thoracolumbar
1.264
59
Neurology; Orthopedics and Sports Medicine; Surgery
Medicine
2,023
35,253,331
The effect of do-it-yourself real-time continuous glucose monitoring on psychological and glycemic variables in children with type 1 diabetes: A randomized crossover trial.
Pediatric diabetes
Pediatr Diabetes
23
4
10.1111/pedi.13331
eng
2,022
6
null
2,022
3
13
[BACKGROUND] Continuous glucose monitoring (CGM) decreases fear of hypoglycemia (FOH) and improves glycemic control among those affected by type 1 diabetes (T1D). No studies to date have examined the impact of using do-it-yourself real-time continuous glucose monitoring (DIY RT-CGM) on psychological and glycemic outcom...
continuous glucose monitoring; do-it-yourself; fear of hypoglycemia; type 1 diabetes
1.343
102
Endocrinology, Diabetes and Metabolism; Internal Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,022
35,253,311
CD158a[+] /CD158b[+] NK cell imbalance correlates with hypertension in patients with pre-eclampsia.
American journal of reproductive immunology (New York, N.Y. : 1989)
Am J Reprod Immunol
87
5
10.1111/aji.13532
eng
2,022
5
null
2,022
3
14
[PROBLEM] Preeclampsia, a pregnancy complication with hypertension and proteinuria, seriously threats the health and lives of the mother and the baby. The pathogenesis of pre-eclampsia remains incompletely understood. The role of peripheral natural killer cells (NK cells) in the pre-eclampsia is unclear. [METHOD OF STU...
CD158a; CD158b; blood pressure; natural killer cells; pre-eclampsia
0.835
119
Immunology and Allergy; Obstetrics and Gynecology; Reproductive Medicine; Immunology
Immunology and Microbiology; Medicine
2,022
35,253,182
ATP2B1 gene rs71454161, rs73196661 and rs73196675 polymorphisms in eclampsia.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
26
4
10.26355/eurrev_202202_28118
eng
2,022
2
null
null
null
null
[OBJECTIVE] We aimed to explore the associations of the ATP2B1 gene polymorphisms with eclampsia. [PATIENTS AND METHODS] A total of 150 patients with eclampsia (disease group) and 150 healthy pregnant women (control group) were taken as the subjects of study. The peripheral blood of the two groups of subjects was colle...
null
null
null
null
null
null
35,252,953
Psychological impact of COVID19 on community pharmacists and pharmacy technicians.
Exploratory research in clinical and social pharmacy
Explor Res Clin Soc Pharm
5
null
10.1016/j.rcsop.2022.100118
eng
2,022
3
null
2,022
3
1
[BACKGROUND] The unique situation related to the COVID-19 outbreak and the consequent worldwide lockdown can have a psychological impact on specific populations. Community pharmacists and pharmacy technicians, as essential healthcare workers on the front line who continue to do their jobs during this pandemic, can also...
COVID-19; Lockdown; Pandemic; Pharmacists; Pharmacy technicians
null
12
Health, Toxicology and Mutagenesis; Pharmacology; Pharmacy
Environmental Science; Health Professions; Medicine
2,022
35,252,895
Performance of an RNA-Based Next-Generation Sequencing Assay for Combined Detection of Clinically Actionable Fusions and Hotspot Mutations in NSCLC.
JTO clinical and research reports
JTO Clin Res Rep
3
2
10.1016/j.jtocrr.2022.100276
eng
2,022
2
null
2,022
1
10
[INTRODUCTION] With its expanding list of approved and emerging therapeutic indications, NSCLC is the exemplar tumor type requiring upfront assessment of several biomarkers to guide clinical management. Next-generation sequencing allows identification of different types of molecular alterations, each with specific anal...
Actionable driver mutations; Anchored multiplex PCR; Next-generation sequencing
0.923
25
Oncology; Pulmonary and Respiratory Medicine
Medicine
2,022
35,252,857
Examining the Relationship Between Basic Psychological Needs and Athlete Identity During the COVID-19 Pandemic.
Frontiers in sports and active living
Front Sports Act Living
4
null
10.3389/fspor.2022.814301
eng
2,022
null
null
2,022
2
16
[OBJECTIVES] During COVID-19 athletes have had games canceled, seasons postponed, and social supports lost. These changes negatively impact their motivation, and potentially identity, as athletes. We draw on self-determination theory to examine motivation in sport and its relationship with athlete identity during COVID...
COVID-19; athlete identity; athletes; basic psychological needs; motivation
0.624
28
Anthropology; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Public Health, Environmental and Occupational Health; Tourism, Leisure and Hospitality Management; Physiology
Biochemistry, Genetics and Molecular Biology; Business, Management and Accounting; Health Professions; Medicine; Social Sciences
2,022
35,252,523
Standardizing HIPEC and perioperative care for patients with ovarian cancer in the Netherlands using a Delphi-based consensus.
Gynecologic oncology reports
Gynecol Oncol Rep
39
null
10.1016/j.gore.2022.100945
eng
2,022
2
null
2,022
2
26
[OBJECTIVE] Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is standard of care in the Netherlands in patients with stage III epithelial ovarian cancer following interval cytoreductive surgery (CRS). Differences in patient selection, technical aspects, and perioperative management exist between centers performing HIP...
CRS, Cytoreductive Surgery; Consensus; Delphi; EOC, Epithelial Ovarian Cancer; HIPEC; HIPEC, Hyperthermic Intraperitoneal Chemotherapy; NACT, Neoadjuvant Chemotherapy; Ovarian cancer
0.406
28
Obstetrics and Gynecology; Oncology
Medicine
2,022
35,252,338
Sigmoid Colon Cancer Masquerading as a Right Incarcerated Inguinal Hernia: A Case Study and Literature Review.
Frontiers in surgery
Front Surg
9
null
10.3389/fsurg.2022.832771
eng
2,022
null
null
2,022
2
17
[BACKGROUND] Indirect inguinal hernia and sigmoid colon cancer are both common diseases, but carcinoma within the hernia sac is rare. We present a case of sigmoid colon cancer masquerading as a right incarcerated inguinal hernia. Since such a presentation is rare, and the correct diagnosis is usually made intraoperativ...
colectomy; hernia repair; incarcerated hernia; physical examination; sigmoid colon cancer
0.459
48
Surgery
Medicine
2,022
35,251,548
Patients Lost to Follow-up in Shoulder Arthroplasty: Descriptive Characteristics and Reasons.
Clinics in orthopedic surgery
Clin Orthop Surg
14
1
10.4055/cios21034
eng
2,022
3
null
2,022
2
15
[BACKGROUND] The purpose of this study was to determine the number of patients lost to follow-up yearly in shoulder arthroplasty and investigate the characteristics of the patients lost to follow-up that may differ from those not lost to follow-up. [METHODS] All shoulder arthroplasties performed from January 2008 to De...
Follow-up; Outcomes; Shoulder arthroplasty
null
null
null
null
null
35,251,542
Does Risk Mitigation Reduce 90-Day Complications in Patients Undergoing Total Knee Arthroplasty?: A Cohort Study.
Clinics in orthopedic surgery
Clin Orthop Surg
14
1
10.4055/cios20234
eng
2,022
3
null
2,022
1
14
[BACKGROUND] With ever-increasing demand for total knee arthroplasty (TKA), most healthcare systems around the world are concerned about its socioeconomic burden. Most centers have universally adopted well-defined clinical care pathways to minimize adverse outcomes, maximize volume, and limit costs. However, there are ...
Complications; Risk mitigation; Total knee arthroplasty
null
null
null
null
null
35,251,401
A randomized controlled trial of emergency LCBDE + LC and ERCP + LC in the treatment of choledocholithiasis with acute cholangitis.
Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques
Wideochir Inne Tech Maloinwazyjne
17
1
10.5114/wiitm.2021.108214
eng
2,022
3
null
2,021
7
30
[INTRODUCTION] Emergency biliary drainage is the basic treatment for acute cholangitis caused by choledocholithiasis. [AIM] To compare the effectiveness and safety of emergency laparoscopic common bile duct exploration combined with laparoscopic cholecystectomy (LCBDE + LC) and endoscopic retrograde cholangiopancreatog...
acute cholangitis; choledocholithiasis; endoscopic retrograde cholangiopancreatography; laparoscopic common bile duct exploration
null
null
null
null
null
35,251,174
Clinical Efficacy and Safety of Bevacizumab, Apatinib, and Recombinant Human Endothelial Inhibitor in the Treatment of Advanced Gastric Cancer.
Journal of oncology
J Oncol
2022
null
10.1155/2022/6189833
eng
2,022
null
null
2,022
2
24
[OBJECTIVE] To investigate the clinical efficacy and safety of bevacizumab, apatinib, and recombinant human endothelial inhibitor in the treatment of advanced gastric cancer. [METHODS] The medical data of 204 patients with a medium to advanced gastric cancer assessed for eligibility treated in our hospital from Februar...
null
null
null
null
null
null
35,251,170
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Journal of oncology
J Oncol
2022
null
10.1155/2022/2352360
eng
2,022
null
null
2,022
2
23
[BACKGROUND] Oral submucous fibrosis (OSF) is a potentially malignant disease of the oral cavity. New molecular predictors are needed to identify the high risk of malignant transformation in potentially malignant oral lesions. Our purpose is to explore PTPRZ1 and p120/β-catenin pathogenesis in the carcinogenesis of OSF...
null
null
null
null
null
null
35,250,898
A Whole-Genome Sequencing-Based Study to Delineate the Risk and Characteristics of Tuberculosis Transmission in an Insular Population Over 10 Years in Shanghai.
Frontiers in microbiology
Front Microbiol
12
null
10.3389/fmicb.2021.768659
eng
2,021
null
null
2,022
2
16
[BACKGROUND] Tuberculosis (TB) has remained a tough problem in China. This study aims to identify the risk of tuberculosis transmission and to assess its characteristics. [METHODS] We performed a molecular epidemiological study for patients with culture-positive Mycobacterium tuberculosis (M. tuberculosis) in Shanghai,...
diagnostic delay; epidemiological investigation; genomic cluster; transmission; tuberculosis; whole-genome sequencing
1.314
259
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,021
35,250,861
The Accuracy of Simple and Adjusted Aldosterone Indices for Assessing Selectivity and Lateralization of Adrenal Vein Sampling in the Diagnosis of Primary Aldosteronism Subtypes.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
13
null
10.3389/fendo.2022.801529
eng
2,022
null
null
2,022
2
16
[OBJECTIVE] This study aimed to evaluate the reliability of simple and corrected aldosterone indices for assessing the selectivity and lateralization of adrenal vein sampling (AVS) in patients with primary aldosteronism. [METHODS] Data of all consecutive patients with primary aldosteronism who underwent AVS for subtype...
adrenal glands; adrenal tumor; adrenalectomy; aldosterone; cortisol; endocrine hypertension; hypokalemia; secondary hypertension
1.278
138
Endocrinology, Diabetes and Metabolism
Medicine
2,022
35,250,854
Microvascular Permeability and Texture Analysis of the Skeletal Muscle of Diabetic Rabbits With Critical Limb Ischaemia Based on DCE-MRI.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
13
null
10.3389/fendo.2022.783163
eng
2,022
null
null
2,022
2
18
[BACKGROUND] We evaluated skeletal muscle vascular permeability in diabetic rabbits with critical limb ischaemia using quantitative dynamic contrast agent-enhanced (DCE) magnetic resonance imaging (MRI) and explored the feasibility of using DCE-MRI K[trans]-based texture analysis for assessing early slight ischaemia-re...
critical limb ischaemia; diabetes; permeability parameter; skeletal muscle; texture analysis
1.278
138
Endocrinology, Diabetes and Metabolism
Medicine
2,022
35,250,285
Statin Prescription Patterns and Associated Factors Among Patients with Type 2 Diabetes Mellitus Attending Diabetic Clinic at Muhimbili National Hospital, Dar es Salaam, Tanzania.
Diabetes, metabolic syndrome and obesity : targets and therapy
Diabetes Metab Syndr Obes
15
null
10.2147/DMSO.S347765
eng
2,022
null
null
2,022
2
27
[PURPOSE] To determine statin prescription patterns and associated factors among type 2 diabetes patients attending the diabetic clinic at Muhimbili National Hospital (MNH) in Dar es Salaam, Tanzania. [PATIENTS AND METHODS] A hospital-based cross-sectional study involving outpatients was conducted from September 2020 t...
Tanzania; prescription; statins; type 2 diabetes
0.851
71
Internal Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,250,273
Prevalence of Internet Addiction and its Correlates Among Regular Undergraduate Medicine and Health Science Students at Ambo University. Cross-Sectional Study.
Substance abuse : research and treatment
Subst Abuse
16
null
10.1177/11782218221080772
eng
2,022
null
null
2,022
2
28
[INTRODUCTION] Internet addiction (IA) is causing academic failure, decreased concentration ability, and a negative affective state. In Ethiopia, studies conducted on IA were limited; therefore, this study aimed to assess its prevalence and risk factors among medicine and health science (MHS) students of Ambo Universit...
Internet addiction; students; university
1.063
0
Medicine; Psychiatry and Mental Health
Medicine
2,022
35,250,226
The Association between Diet Quality Scores with Sleep Quality among Employees: A Cross-Sectional Study.
Ethiopian journal of health sciences
Ethiop J Health Sci
32
1
10.4314/ejhs.v32i1.16
eng
2,022
1
null
null
null
null
[BACKGROUND] Numerous factors such as nutrition and diet can affect the quality of sleep of people, especially employees. The aim of this study was to investigate the relationship between university employees' sleep quality and their dietary quality scores (HEI, DII and DASH score). [MATERIALS AND METHODS] This cross-s...
DASH; Healthy Eating Index; Sleep quality
null
null
null
null
null
35,250,223
Malpractice Awareness among Surgeons and Surgical Trainees in Ethiopia.
Ethiopian journal of health sciences
Ethiop J Health Sci
32
1
10.4314/ejhs.v32i1.13
eng
2,022
1
null
null
null
null
[BACKGROUND] In Ethiopia, a country where seeing medical errors is not rare, there is a lack of data concerning the overall awareness of medical malpractice issues among physicians. A recent study showed that 80% of malpractice claims in Ethiopia are related to some form of surgery or operation room activities. [METHOD...
attitudes; knowledge; malpractice; negligence; practices; surgeon
null
null
null
null
null
35,249,851
The impact of the modified frailty index on clinical outcomes for patients with stage IV non-small cell lung cancer receiving chemotherapy.
Journal of geriatric oncology
J Geriatr Oncol
13
5
10.1016/j.jgo.2022.02.015
eng
2,022
6
null
2,022
3
4
[INTRODUCTION] Frailty impacts outcomes for patients with lung cancer, but no brief tools have been assessed in patients with metastatic disease. We evaluated the impact of the Modified Frailty Index (mFI) on clinical outcomes for patients with metastatic non-small cell lung cancer (NSCLC). [METHODS] We conducted a ret...
Cytotoxic chemotherapy; Frailty; Outcomes research; Prognosis; Toxicity
1.025
58
Geriatrics and Gerontology; Oncology
Medicine
2,022
35,249,706
Mechanism-based pharmacodynamic model for propofol haemodynamic effects in healthy volunteers[☆].
British journal of anaesthesia
Br J Anaesth
128
5
10.1016/j.bja.2022.01.022
eng
2,022
5
null
2,022
3
3
[BACKGROUND] The adverse haemodynamic effects of the intravenous anaesthetic propofol are well known, yet few empirical models have explored the dose-response relationship. Evidence suggests that hypotension during general anaesthesia is associated with postoperative mortality. We developed a mechanism-based model that...
haemodynamic effects; healthy volunteers; mechanism-based pharmacodynamic modelling; pharmacology; propofol
2.487
222
Anesthesiology and Pain Medicine
Medicine
2,022
35,249,626
A national landscape: Injury and violence prevention health equity scan findings and implications for the field of practice.
Journal of safety research
J Safety Res
80
null
10.1016/j.jsr.2021.12.026
eng
2,022
2
null
2,021
12
31
[INTRODUCTION] Many federal and national partners have a renewed commitment to addressing health equity and racial equity as a public health issue of concern. These are especially important issues in addressing many injury and violence prevention (IVP) topic areas. In developing and updating approaches to address injur...
Health disparities; Health equity; Injury and violence prevention; Racial equity; Social determinants of health
1.109
110
Safety, Risk, Reliability and Quality
Engineering
2,022
35,249,617
Promoting farming sustainability: The effects of age, training, history of accidents and social-psychological variables on the adoption of on-farm safety behaviors.
Journal of safety research
J Safety Res
80
null
10.1016/j.jsr.2021.12.018
eng
2,022
2
null
2,021
12
28
[INTRODUCTION] Occupational safety and health (OSH) have a remarkable impact on the sustainability of firms and organizations. However, the sustainability perspective has often focused primarily on environmental and economic concerns, leaving key social and workplace aspects, such as OSH, underemphasized. The link betw...
Italy; Near misses; Occupational safety; Safety training; Sustainable agriculture; Theory of Planned Behavior
1.109
110
Safety, Risk, Reliability and Quality
Engineering
2,022
35,249,535
Impact of different cover letter content and incentives on non-response bias in a sample of Veterans applying for Department of Veterans Affairs disability benefits: a randomized, 3X2X2 factorial trial.
BMC medical research methodology
BMC Med Res Methodol
22
1
10.1186/s12874-022-01531-x
eng
2,022
3
6
2,022
3
6
[BACKGROUND] Non-random non-response bias in surveys requires time-consuming, complicated, post-survey analyses. Our goal was to see if modifying cover letter information would prevent non-random non-response bias altogether. Our secondary goal tested whether larger incentives would reduce non-response bias. [METHODS] ...
Combat; Factorial design; Leverage salience theory; Mailed survey; Military sexual trauma; Non-response Bias; Randomized trial; Sexual assault
1.778
176
Epidemiology; Health Informatics
Medicine
2,022
35,249,412
Treatment of redo-microvascular decompression or internal neurolysis plus microvascular decompression for recurrent trigeminal neuralgia: a review of long-term effectiveness and safety.
The Journal of international medical research
J Int Med Res
50
3
10.1177/03000605221080721
eng
2,022
3
null
null
null
null
[OBJECTIVE] We examined the clinical characteristics and outcomes of patients with recurrent trigeminal neuralgia (TN) and assessed the long-term efficacy and safety of microvascular decompression (MVD) to treat typical recurrent TN. [METHODS] We identified 3024 patients who underwent MVD for treatment of TN at the Chi...
Recurrent trigeminal neuralgia; efficacy; long-term outcome; microvascular decompression; pain; safety; treatment
0.393
74
Biochemistry; Biochemistry; Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,248,877
Therapeutic drug monitoring of sertraline in children and adolescents: A naturalistic study with insights into the clinical response and treatment of obsessive-compulsive disorder.
Comprehensive psychiatry
Compr Psychiatry
115
null
10.1016/j.comppsych.2022.152301
eng
2,022
5
null
2,022
2
26
[BACKGROUND] Sertraline is a selective serotonin reuptake inhibitor with specific indications in child and adolescent psychiatry. Notwithstanding its frequent use and clinical benefits, the relationship between pharmacokinetics, pharmacodynamics, efficacy, and tolerability of sertraline across indications, particularly...
TDM; antidepressants; pharmacovigilance; selective serotonin reuptake inhibitors; steady state concentration
1.869
128
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
35,248,790
Influence of residual anterior laxity on functional outcomes after anterior cruciate ligament reconstruction.
Orthopaedics traumatology, surgery research : OTSR
Orthop Traumatol Surg Res
108
3
10.1016/j.otsr.2022.103264
eng
2,022
5
null
2,022
3
4
[INTRODUCTION] Residual laxity can persist after anterior cruciate ligament (ACL) reconstruction. This increased anterior translation can be measured with a knee arthrometer. Nevertheless, the measurement parameters and functional impact of this residual laxity are not well understood. The aims of this study were to (1...
Anterior cruciate ligament reconstruction; Knee arthrometer; Knee instability; Laxity
null
null
null
null
null
35,248,742
Vascular Surgeon Burnout and Resilience in the United Kingdom: A Report from the Vascular Society Workforce Committee.
Annals of vascular surgery
Ann Vasc Surg
84
null
10.1016/j.avsg.2022.01.032
eng
2,022
8
null
2,022
3
3
[BACKGROUND] Occupational burnout is a growing concern in frontline roles such as vascular surgery, and is associated with medical errors and shortened careers. Our aim is to measure burnout, resilience, and associated risk factors among vascular surgeons (VS) in the United Kingdom (UK). [METHODS] We carried out an ele...
null
0.65
87
Cardiology and Cardiovascular Medicine; Medicine; Surgery
Medicine
2,022
35,248,571
Endoscopic gastroplasty versus laparoscopic sleeve gastrectomy: a noninferiority propensity score-matched comparative study.
Gastrointestinal endoscopy
Gastrointest Endosc
96
1
10.1016/j.gie.2022.02.050
eng
2,022
7
null
2,022
3
3
[BACKGROUND AND AIMS] Endoscopic bariatric therapies are less-invasive alternatives to bariatric surgery, and endoscopic gastroplasty (ESG) represents the latest evolution. This study aims to compare weight loss, safety, and comorbidity resolution of ESG compared with laparoscopic sleeve gastrectomy (LSG). [METHODS] Th...
null
2.046
236
Gastroenterology; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,248,104
RUNX1 inhibits the antiviral immune response against influenza A virus through attenuating type I interferon signaling.
Virology journal
Virol J
19
1
10.1186/s12985-022-01764-8
eng
2,022
3
5
2,022
3
5
[BACKGROUND] Influenza A viruses (IAVs) are zoonotic, segmented negative-stranded RNA viruses. The rapid mutation of IAVs results in host immune response escape and antiviral drug and vaccine resistance. RUNX1 is a transcription factor that not only plays essential roles in hematopoiesis, but also functions as a regula...
A549; IFN; IRF3; Influenza A virus; RUNX1; STAT1
1.092
104
Infectious Diseases; Virology
Immunology and Microbiology; Medicine
2,022
35,248,061
Inequal distribution of nursing personnel: a subnational analysis of the distribution of nurses across 58 countries.
Human resources for health
Hum Resour Health
20
1
10.1186/s12960-022-00720-5
eng
2,022
3
5
2,022
3
5
[BACKGROUND] Nursing personnel are critical for enabling access to health service in primary health care. However, the State of the World's Nursing 2020 report showed important inequalities in nurse availability between countries. [METHODS] The purpose of this study/analysis was to describe the differences in nurse-to-...
Demography; Health workforce; Healthcare disparities; Nursing
1.203
89
Public Administration; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,022
35,248,030
Medical student's perception of the COVID-19 pandemic effect on their education and well-being: a cross-sectional survey in the United States.
BMC medical education
BMC Med Educ
22
1
10.1186/s12909-022-03197-x
eng
2,022
3
5
2,022
3
5
[BACKGROUND] The effects of drastic curricular changes necessitated by the COVID-19 pandemic on medical students' education and wellbeing have remained largely unstudied. Out study aimed to characterize how medical students were affected by the pandemic, specifically how limitations introduced by the pandemic may have ...
COVID-19; Coronavirus; Medical education; Pandemic; Student wellbeing; United States
0.914
107
Education; Medicine
Medicine; Social Sciences
2,022
35,248,020
Different inflammatory blood markers correlate with specific outcomes in incident HPV-negative head and neck squamous cell carcinoma: a retrospective cohort study.
BMC cancer
BMC Cancer
22
1
10.1186/s12885-022-09327-4
eng
2,022
3
5
2,022
3
5
[BACKGROUND] Inflammatory blood markers have been associated with oncological outcomes in several cancers, but evidence for head and neck squamous cell carcinoma (HNSCC) is scanty. Therefore, this study aims at investigating the association between five different inflammatory blood markers and several oncological outco...
Blood markers; Head and neck cancer; Inflammatory system; Local recurrence; Overall survival
1.137
171
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,247,938
Evaluating Public Participation in a Deliberative Dialogue: A Single Case Study.
International journal of health policy and management
Int J Health Policy Manag
11
11
10.34172/ijhpm.2022.6588
eng
2,022
12
6
2,022
2
28
[BACKGROUND] Deliberative dialogues (DDs) are used in policy-making and healthcare research to enhance knowledge exchange and research implementation strategies. They allow organized dissemination and integration of relevant research, contextual considerations, and input from diverse stakeholder perspectives. Despite r...
Community Engagement; Deliberative Dialogue; Knowledge Translation; Public Engagement; Public Involvement; Stakeholder Consultation
1.155
56
Health Information Management; Health Policy; Health; Leadership and Management; Management, Monitoring, Policy and Law
Environmental Science; Health Professions; Medicine; Nursing; Social Sciences
2,022
35,247,631
The Critical and Diverse Roles of CD4[-]CD8[-] Double Negative T Cells in Nonalcoholic Fatty Liver Disease.
Cellular and molecular gastroenterology and hepatology
Cell Mol Gastroenterol Hepatol
13
6
10.1016/j.jcmgh.2022.02.019
eng
2,022
null
null
2,022
3
2
[BACKGROUND AND AIMS] Hepatic inflammation is a hallmark of nonalcoholic fatty liver disease (NAFLD). Double negative T (DNT) cells are a unique subset of T lymphocytes that do not express CD4, CD8, or natural killer cell markers, and studies have suggested that DNT cells play critical and diverse roles in the immune s...
GZMB; IL17A; NAFLD
2.454
75
Gastroenterology; Hepatology
Medicine
2,022
35,247,513
Improved Accuracy of Coronal Alignment Can Be Attained Using 3D-Printed Patient-Specific Instrumentation for Knee Osteotomies: A Systematic Review of Level III and IV Studies.
Arthroscopy : the journal of arthroscopic related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Arthroscopy
38
9
10.1016/j.arthro.2022.02.023
eng
2,022
9
null
2,022
3
2
[PURPOSE] To evaluate the accuracy and precision of postoperative coronal plane alignment using 3D-printed patient-specific instrumentation (PSI) in the setting of proximal tibial or distal femoral osteotomies. [METHODS] A systematic review evaluating the accuracy of 3D-printed PSI for coronal plane alignment correctin...
null
null
null
null
null
null
35,247,336
The three-dimensional structural configuration of the central retinal vessel trunk and branches as a glaucoma biomarker.
American journal of ophthalmology
Am J Ophthalmol
240
null
10.1016/j.ajo.2022.02.020
eng
2,022
8
null
2,022
3
2
[PURPOSE] To assess whether the 3-dimensional (3D) structural configuration of the central retinal vessel trunk and its branches (CRVTB) could be used as a diagnostic marker for glaucoma. [DESIGN] Retrospective, deep-learning approach diagnosis study. [METHODS] We trained a deep learning network to automatically segmen...
null
1.895
221
Ophthalmology
Medicine
2,022
35,247,194
Improving the Safety of Medicines via Digital Technology: An Assessment of the Scope and Quality of Risk Minimization Websites in the United States and United Kingdom.
Drug safety
Drug Saf
45
3
10.1007/s40264-022-01165-4
eng
2,022
3
null
2,022
3
5
[INTRODUCTION] EHealth holds tremendous promise for enhancing drug safety initiatives known as risk minimization programs. Little is known, however, regarding the scope and quality of existing risk minimization websites. [METHODS] Two publicly accessible repositories, REMS@FDA [1] and Electronic Medicines Compendium [2...
null
1.105
146
Pharmacology; Pharmacology; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,246,911
Trajectories of muscle quantity, quality and function measurements in hospitalized older adults.
Geriatrics gerontology international
Geriatr Gerontol Int
22
4
10.1111/ggi.14366
eng
2,022
4
null
2,022
3
4
[AIM] Acute sarcopenia is defined by the development of incident sarcopenia (low muscle quantity/quality and function) within 6 months of a stressor event. However, outcome measures for clinical trials have not been validated. This study aimed to characterize changes in muscle quantity, quality, strength, and physical ...
acute sarcopenia; deconditioning; echogenicity; physical function; ultrasound
null
null
null
null
null
35,246,899
Effect of Internal Design Modification on the Mechanical Properties of Laser Sintered Cobalt-Chromium Multi-Unit Metal-Ceramic Frameworks.
Journal of prosthodontics : official journal of the American College of Prosthodontists
J Prosthodont
31
9
10.1111/jopr.13501
eng
2,022
12
null
2,022
3
22
[PURPOSE] The purpose of the study was to assess the effect of internal design modifications on the mechanical properties of multi-unit Cobalt-Chromium (Co-Cr) metal-ceramic frameworks manufactured by direct metal laser sintering. [MATERIAL AND METHODS] Four-unit fixed partial denture metal-ceramic frameworks were digi...
Direct metal laser sintering; flexural modulus; flexural strength; internal modification
1.225
87
Dentistry
Dentistry
2,022
35,246,484
Associations between high ambient temperatures and asthma exacerbation among children in Philadelphia, PA: a time series analysis.
Occupational and environmental medicine
Occup Environ Med
79
5
10.1136/oemed-2021-107823
eng
2,022
5
null
2,022
3
4
[OBJECTIVES] High ambient temperatures may contribute to acute asthma exacerbation, a leading cause of morbidity in children. We quantified associations between hot-season ambient temperatures and asthma exacerbation in children ages 0-18 years in Philadelphia, PA. [METHODS] We created a time series of daily counts of ...
asthma; climate; environment; environmental pollution; public health
1.149
167
Public Health, Environmental and Occupational Health
Medicine
2,022
35,246,361
High Survivorship of a Modular Titanium Baseplate Independent of Body Mass Index and Malalignment.
The Journal of arthroplasty
J Arthroplasty
37
6S
10.1016/j.arth.2022.02.006
eng
2,022
6
null
2,022
2
18
[BACKGROUND] Tibial component aseptic loosening remains problematic in primary total knee arthroplasty (TKA). Influential factors include component design, metallurgy, and cement technique. Additionally, reports advocate for longer tibial stem fixation in high body mass index (BMI) patients. We have utilized a single s...
aseptic loosening; postoperative malalignment; survivorship; titanium baseplate; total knee arthroplasty
2.028
171
Orthopedics and Sports Medicine
Medicine
2,022
35,246,286
Changes in Burnout and Satisfaction With Work-Life Integration in Physicians and the General US Working Population Between 2011 and 2020.
Mayo Clinic proceedings
Mayo Clin Proc
97
3
10.1016/j.mayocp.2021.11.021
eng
2,022
3
null
null
null
null
[OBJECTIVE] To evaluate the prevalence of burnout and satisfaction with work-life integration (WLI) among physicians and US workers in 2020 relative to 2011, 2014, and 2017. [METHODS] Between November 20, 2020, and March 23, 2021, we surveyed US physicians and a probability-based sample of the US working population usi...
null
2.056
221
Medicine
Medicine
2,022
35,246,207
An update on radiomics techniques in primary liver cancers.
Infectious agents and cancer
Infect Agent Cancer
17
1
10.1186/s13027-022-00422-6
eng
2,022
3
4
2,022
3
4
[BACKGROUND] Radiomics is a progressing field of research that deals with the extraction of quantitative metrics from medical images. Radiomic features detention indirectly tissue features such as heterogeneity and shape and can, alone or in combination with demographic, histological, genomic, or proteomic data, be use...
Cholangiocarcinoma; Hepatocellular carcinoma; Machine learnings; Radiomics; Texture analysis
0.583
50
Cancer Research; Epidemiology; Infectious Diseases; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,246,120
Increased serum LOXL2 concentration in pelvic inflammatory disease with pelvic adhesion.
BMC women's health
BMC Womens Health
22
1
10.1186/s12905-022-01640-1
eng
2,022
3
4
2,022
3
4
[BACKGROUND] Lysyl oxidase-like 2 (LOXL2) belongs to a family of the LOX secretory enzyme, which involves the cross-linkage of extracellular matrix (ECM) proteins. Here, we aimed to analyze the correlation between serum LOXL2 and pelvic adhesion in chronic pelvic inflammatory disease (PID). [METHODS] A total of 143 pat...
Lysyl oxidase-like 2; Pelvic adhesion; Pelvic inflammatory disease
0.775
73
Medicine; Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,022
35,246,119
Design and evaluation of a mobile-based nutrition education application for infertile women in Iran.
BMC medical informatics and decision making
BMC Med Inform Decis Mak
22
1
10.1186/s12911-022-01793-x
eng
2,022
3
4
2,022
3
4
[BACKGROUND] The prevalence of infertility in Iran is higher than the world average. Furthermorte, education and nutrition are among the effective factors in improving the quality of life of women with infertility. According to the significant role of smartphones in people's lives as well as health education, the prese...
Infertility; Mobile app; Mobile health; Nutrition education; Usability
0.94
107
Health Policy; Computer Science Applications; Health Informatics
Computer Science; Medicine
2,022
35,245,822
Reliability of negative cone specimens of the cervix: A review.
Annals of diagnostic pathology
Ann Diagn Pathol
58
null
10.1016/j.anndiagpath.2022.151929
eng
2,022
6
null
2,022
2
26
[OBJECTIVES] Cervical conization specimens with a negative result for high-grade lesion are not infrequent in clinical practice and there are no protocols to address this issue. The purpose of this manuscript is to analyze factors that affect the reliability on these situations and provide recommendations to guide the ...
Cervical intraepithelial neoplasia; Conization; HPV; Ki-67 antigen; Negative results; p16
0.603
69
Medicine; Pathology and Forensic Medicine
Medicine
2,022