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35,193,914 | Nutrigenetics, omega-3 and plasma lipids/lipoproteins/apolipoproteins with evidence evaluation using the GRADE approach: a systematic review. | BMJ open | BMJ Open | 12 | 2 | 10.1136/bmjopen-2021-054417 | eng | 2,022 | 2 | 22 | 2,022 | 2 | 22 | [OBJECTIVES] Despite the uptake of nutrigenetic testing through direct-to-consumer services and healthcare professionals, systematic reviews determining scientific validity are limited in this field. The objective of this review was to: retrieve, synthesise and assess the quality of evidence (confidence) for nutrigenet... | genetics; lipid disorders; nutrition dietetics | 1.059 | 176 | Medicine | Medicine | 2,022 |
35,193,819 | Cabozantinib in Patients with Advanced Renal Cell Carcinoma Primary Refractory to First-line Immunocombinations or Tyrosine Kinase Inhibitors. | European urology focus | Eur Urol Focus | 8 | 6 | 10.1016/j.euf.2022.02.004 | eng | 2,022 | 11 | null | 2,022 | 2 | 19 | [BACKGROUND] A subset of patients with metastatic renal cell carcinoma (mRCC), deemed as primary refractory, shows progressive disease as the best response to first-line therapy even when treated with novel immune-based combos. [OBJECTIVE] We aimed to assess the outcome of patients treated with second-line cabozantinib... | Cabozantinib; First line; Primary refractory; Renal cell carcinoma; Second line | 1.548 | 60 | Urology | Medicine | 2,022 |
35,193,795 | Immediate Radiology Report Access: A Burden to the Ordering Provider. | Current problems in diagnostic radiology | Curr Probl Diagn Radiol | 51 | 5 | 10.1067/j.cpradiol.2022.01.012 | eng | 2,022 | null | null | 2,022 | 1 | 31 | [PURPOSE] Many practices have eliminated their delayed-release of radiology report programs in response to anticipated penalties under the information-blocking provision of the 21st Century Cures Act. Our purpose is to share the results and suggestions from a survey of our referring providers regarding the impact of th... | null | 0.389 | 43 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,022 |
35,193,702 | Glyphosate induces immune dysregulation in honey bees. | Animal microbiome | Anim Microbiome | 4 | 1 | 10.1186/s42523-022-00165-0 | eng | 2,022 | 2 | 22 | 2,022 | 2 | 22 | [BACKGROUND] Similar to many other animals, the honey bee Apis mellifera relies on a beneficial gut microbiota for regulation of immune homeostasis. Honey bees exposed to agrochemicals, such as the herbicide glyphosate or antibiotics, usually exhibit dysbiosis and increased susceptibility to bacterial infection. Consid... | Cellular immunity; Glyphosate; Honey bees; Humoral immunity; Microbiome; Tylosin | null | null | null | null | null |
35,193,603 | Effects of medical insurance system on the hospitalization cost of acute myocardial infarction patients. | Cost effectiveness and resource allocation : C/E | Cost Eff Resour Alloc | 20 | 1 | 10.1186/s12962-022-00343-6 | eng | 2,022 | 2 | 22 | 2,022 | 2 | 22 | [BACKGROUND] Acute myocardial infarction is still a burden on Chinese patients. Whether different medical insurance system have any influence on the hospitalization cost and therapeutic effect of acute myocardial infarction patient needs further investigation. [METHOD] In this study, 600 patients were stratified by hea... | Acute myocardial infarction; Cost effectiveness; Health insurance status; Nursing | 0.53 | 46 | Health Policy | Medicine | 2,022 |
35,193,580 | CD98hc has a pivotal role in maintaining the immuno-barrier integrity of basal layer cells in esophageal epithelium. | Cancer cell international | Cancer Cell Int | 22 | 1 | 10.1186/s12935-021-02399-5 | eng | 2,022 | 2 | 22 | 2,022 | 2 | 22 | [OBJECTIVES] The current study aims to find the linker between esophageal epithelial carcinogenesis and chronic inflammation and the origin of hyperproliferative cells in precancerous lesions of esophageal squamous cell carcinoma (ESCC). [MATERIALS AND METHODS] Twenty one normal esophageal tissues from cadavers and 180... | Carcinogenesis; Chronic inflammation; Esophageal squamous cell carcinoma | 1.145 | 90 | Genetics; Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,193,408 | Empowering Low-Income Asian American Women to Conduct Human Papillomavirus Self-Sampling Test: A Community-Engaged and Culturally Tailored Intervention. | Cancer control : journal of the Moffitt Cancer Center | Cancer Control | 29 | null | 10.1177/10732748221076813 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Asian American women face disproportionate burden of cervical cancer (CC) than non-Hispanic white women in the U.S. The goal of this study was to assess the feasibility and impact of a culturally tailored intervention to promote Human papillomavirus (HPV) self-sampling test among hard-to-reach Asian Americ... | Asian American women; cervical cancer prevention; community-based participatory research; human papilloma virus; human papillomavirus self-test | null | null | null | null | null |
35,192,634 | Factors associated with antenatal exercise in Arba Minch town, Southern Ethiopia: A community-based cross-sectional study. | PloS one | PLoS One | 17 | 2 | 10.1371/journal.pone.0260840 | eng | 2,022 | null | null | 2,022 | 2 | 22 | [BACKGROUND] Many health risks in pregnant women and their foetuses can be reduced by practicing antenatal exercise. However, the adequate practice of antenatal exercise among pregnant women is low in Ethiopia. Therefore, this study aimed to assess the practice of antenatal exercise and its associated factors among pre... | null | 0.885 | 467 | Multidisciplinary | Multidisciplinary | 2,022 |
35,191,961 | Effect of Physiological Oxygen on Primary Human Corneal Endothelial Cell Cultures. | Translational vision science technology | Transl Vis Sci Technol | 11 | 2 | 10.1167/tvst.11.2.33 | eng | 2,022 | 2 | 1 | null | null | null | [PURPOSE] Primary human corneal endothelial cells (HCEnCs) cultured in room air are exposed to significantly higher O2 concentrations [O2] than what is normally present in the eye. We evaluated the growth and metabolism of HCEnCs cultured under physiological [O2] (2.5%; [O2]2.5) and room air ([O2]A). [METHODS] Primary ... | null | null | null | null | null | null |
35,191,609 | The real-world clinical outcomes and treatment patterns of patients with unresectable locally advanced or metastatic soft tissue sarcoma treated with anlotinib in the post-ALTER0203 trial era. | Cancer medicine | Cancer Med | 11 | 11 | 10.1002/cam4.4613 | eng | 2,022 | 6 | null | 2,022 | 2 | 22 | [BACKGROUND] The ALTER0203 clinical trial showed that anlotinib, a multitargeted tyrosine kinase inhibitor, had antitumor effects on advanced soft tissue sarcoma (STS) after the failure of standard chemotherapy. We aimed to evaluate the real-world efficacy and explore prognostic factors and treatment patterns of anloti... | clinical management; nutrition; prognosis; soft tissue sarcoma; target therapy; tyrosine kinase inhibitors | 1.188 | 95 | Oncology; Radiology, Nuclear Medicine and Imaging; Cancer Research | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,191,466 | PET-Based Radiogenomics Supports mTOR Pathway Targeting for Hepatocellular Carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research | Clin Cancer Res | 28 | 9 | 10.1158/1078-0432.CCR-21-3208 | eng | 2,022 | 5 | 2 | null | null | null | [PURPOSE] This work aimed to explore in depth the genomic and molecular underpinnings of hepatocellular carcinoma (HCC) with increased 2[18F]fluoro-2-deoxy-d-glucose (FDG) uptake in PET and to identify therapeutic targets based on this imaging-genomic surrogate. [EXPERIMENTAL DESIGN] We used RNA sequencing and whole-ex... | null | 4.603 | 392 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,191,411 | Tidal Volume-Dependent Activation of the Renin-Angiotensin System in Experimental Ventilator-Induced Lung Injury. | Critical care medicine | Crit Care Med | 50 | 9 | 10.1097/CCM.0000000000005495 | eng | 2,022 | 9 | 1 | 2,022 | 2 | 22 | [OBJECTIVES] Ventilator-induced lung injury (VILI) is a major contributor to morbidity and mortality in critically ill patients. Mechanical damage to the lungs is potentially aggravated by the activation of the renin-angiotensin system (RAS). This article describes RAS activation profiles in VILI and discusses the effe... | null | 2.785 | 315 | Critical Care and Intensive Care Medicine | Medicine | 2,022 |
35,191,332 | Comparison of histopathological features, survival, and oncological outcome between patients under and above 55-year-old with prostate cancer who underwent radical prostatectomy. | Urologia | Urologia | 90 | 1 | 10.1177/03915603221078266 | eng | 2,023 | 2 | null | 2,022 | 2 | 22 | [BACKGROUND] To compare the disease course, histopathological features and survival rates of prostate cancer (PCa) between patients aged ⩽ 55 and 55 year old. [MATERIALS AND METHODS] In this retrospective study, we enrolled 644 patients with organ-confide prostate cancer who had undergone radical prostatectomy from 20... | Prostate cancer; age groups; radical prostatectomy; survival rate | null | null | null | null | null |
35,191,069 | The cost-effectiveness of radial access percutaneous coronary intervention: A propensity-score matched analysis of Victorian data. | Clinical cardiology | Clin Cardiol | 45 | 4 | 10.1002/clc.23798 | eng | 2,022 | 4 | null | 2,022 | 2 | 22 | [BACKGROUND] Despite evidence of the comparative benefits of transradial access percutaneous coronary intervention (PCI) over transfemoral access, its uptake remains highly varied across Australia. Few studies have explored the implications of the choice of access site during PCI from the perspective of the Australian ... | acute coronary syndrome; cost-effectiveness; health economics; percutaneous coronary intervention | 0.806 | 89 | Cardiology and Cardiovascular Medicine; Medicine | Medicine | 2,022 |
35,191,023 | Landscape genetics of the tropical willow Salix humboldtiana: influence of climate, salinity, and orography in an altitudinal gradient. | American journal of botany | Am J Bot | 109 | 3 | 10.1002/ajb2.1824 | eng | 2,022 | 3 | null | 2,022 | 3 | 25 | [PREMISE] Gene flow in riparian ecosystems is influenced by landscape features such as orography, climate, and salinity. The downstream increase in genetic diversity (DIGD) hypothesis states that the unidirectionality of the watercourse causes an accumulation of genetic diversity toward downstream populations, while up... | DIGD hypothesis; Mexico; Salicaceae; gene flow; genetic structure; resistance analysis; riparian tree | 0.863 | 178 | Ecology, Evolution, Behavior and Systematics; Plant Science; Genetics | Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology | 2,022 |
35,190,970 | Treatment Patterns and Outcomes Before and After Humulin R U-500 Initiation Among US Patients with Type 2 Diabetes Previously Prescribed ≤ 200 Units/day of U-100 Insulin. | Diabetes therapy : research, treatment and education of diabetes and related disorders | Diabetes Ther | 13 | 3 | 10.1007/s13300-022-01209-z | eng | 2,022 | 3 | null | 2,022 | 2 | 21 | [INTRODUCTION] Humulin R U-500 (U-500R) utilization has increased in the past few years, raising concerns as U-500R is indicated only for patients requiring 200 units of insulin. Thus, evidence of dispensed total daily dose (dTDD) 200 units of prior U-100 insulin based on pharmacy claims is increasingly used as a cri... | Concentrated insulin; Glycemic control | 1.039 | 59 | Endocrinology, Diabetes and Metabolism; Internal Medicine | Medicine | 2,022 |
35,190,928 | Semaphorin 3D inhibits proliferation and migration of papillary thyroid carcinoma by regulating MAPK/ERK signaling pathway. | Molecular biology reports | Mol Biol Rep | 49 | 5 | 10.1007/s11033-022-07220-8 | eng | 2,022 | 5 | null | 2,022 | 2 | 21 | [BACKGROUND] Semaphorin 3D (SEMA3D) plays an important role in the occurrence and development of multifarious cancers. However, the relationship between SEMA3D and papillary thyroid carcinoma (PTC) remains unclear. This study aimed to investigate the functions and mechanism of SEMA3D in papillary thyroid carcinoma (PTC... | Migration; Papillary thyroid carcinoma; Proliferation; SEMA3D | 0.578 | 96 | Medicine; Genetics; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,190,385 | Baricitinib for relapsing giant cell arteritis: a prospective open-label 52-week pilot study. | Annals of the rheumatic diseases | Ann Rheum Dis | 81 | 6 | 10.1136/annrheumdis-2021-221961 | eng | 2,022 | 6 | null | 2,022 | 2 | 21 | [BACKGROUND/PURPOSE] Preclinical vascular inflammation models have demonstrated effective suppression of arterial wall lesional T cells through inhibition of Janus kinase 3 and JAK1. However, JAK inhibition in patients with giant cell arteritis (GCA) has not been prospectively investigated. [METHODS] We performed a pro... | giant cell arteritis; systemic vasculitis; therapeutics | 6.489 | 300 | Biochemistry, Genetics and Molecular Biology; Immunology; Immunology and Allergy; Rheumatology | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,022 |
35,190,375 | Clinical efficacy of atezolizumab plus bevacizumab and chemotherapy in KRAS-mutated non-small cell lung cancer with STK11, KEAP1, or TP53 comutations: subgroup results from the phase III IMpower150 trial. | Journal for immunotherapy of cancer | J Immunother Cancer | 10 | 2 | 10.1136/jitc-2021-003027 | eng | 2,022 | 2 | null | null | null | null | [BACKGROUND] The efficacy of atezolizumab (A) and/or bevacizumab (B) with carboplatin/paclitaxel (CP) chemotherapy was explored in the phase III, randomized IMpower150 study in patients with non-squamous non-small cell lung cancer (NSCLC) according to KRAS mutations (mKRAS) and co-occurring STK11, KEAP1, or TP53 mutati... | biomarkers; immunotherapy; lung neoplasms; programmed cell death 1 receptor; tumor; tumor biomarkers | 3.403 | 136 | Cancer Research; Immunology; Immunology and Allergy; Molecular Medicine; Oncology; Pharmacology | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,022 |
35,190,300 | Diagnostic role of internal mammary lymph node involvement in tuberculous pleurisy: a multicenter study. | Pulmonology | Pulmonology | 30 | 4 | 10.1016/j.pulmoe.2022.01.010 | eng | 2,024 | null | null | 2,022 | 2 | 18 | [BACKGROUND AND OBJECTIVES] Diagnosis of tuberculous pleurisy (TP) may be challenging and it often requires pleural biopsy. A tool able to increase pre-test probability of TP may be helpful to guide diagnostic work-up and enlargement of internal mammary lymph node (IMLN) has been suggested to play a potential role. The... | Computed tomography; Diagnosis; Internal mammary lymph node; Pleural effusion; Thoracic ultrasound; Tuberculosis; Tuberculous pleurisy | 1.434 | 43 | Pulmonary and Respiratory Medicine | Medicine | 2,024 |
35,190,261 | Characterization of True and False Positive Findings on Contrast-Enhanced Mammography. | Academic radiology | Acad Radiol | 29 | 11 | 10.1016/j.acra.2022.01.006 | eng | 2,022 | 11 | null | 2,022 | 2 | 18 | [RATIONALE AND OBJECTIVES] The purpose of this paper is to characterize true and false positive findings on contrast-enhanced mammography (CEM) and correlate enhancement pattern and method of detection with pathology outcomes. [MATERIALS AND METHODS] This was an IRB-approved retrospective review of diagnostic CEM perfo... | Contrast-enhanced mammography; Diagnostic mammography; False positive | 1.064 | 113 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,022 |
35,189,999 | What predicts persisting social impairment following pediatric traumatic brain injury: contribution of a biopsychosocial approach. | Psychological medicine | Psychol Med | 53 | 8 | 10.1017/S0033291722000186 | eng | 2,023 | 6 | null | 2,022 | 2 | 22 | [BACKGROUND] Psychosocial deficits, such as emotional, behavioral and social problems, reflect the most common and disabling consequences of pediatric traumatic brain injury (TBI). Their causes and recovery likely differ from physical and cognitive skills, due to disruption to developing brain networks and the influenc... | Behavior; brain injury; child; recovery; social cognition; social impairment | 2.768 | 251 | Applied Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,023 |
35,189,958 | circCUL2 induces an inflammatory CAF phenotype in pancreatic ductal adenocarcinoma via the activation of the MyD88-dependent NF-κB signaling pathway. | Journal of experimental clinical cancer research : CR | J Exp Clin Cancer Res | 41 | 1 | 10.1186/s13046-021-02237-6 | eng | 2,022 | 2 | 21 | 2,022 | 2 | 21 | [BACKGROUND] Pancreatic ductal adenocarcinoma (PDAC) is characterized by clusters of cancer cells surrounded by a dense desmoplastic stroma. However, little is known about stromal cell heterogeneity in the pancreatic tumor microenvironment. [METHODS] We conducted circRNA profiling in primary fibroblasts by high-through... | Inflammatory CAF; MyD88; Pancreatic ductal adenocarcinoma; circCUL2 | null | null | null | null | null |
35,189,799 | Research Advancements on Fluorinated and Non-Fluorinated 4- Phenyl(thio)ureido-Substituted 2,2-Dimethylchromans Acting as Inhibitors of Insulin Release and Smooth Muscle Relaxants. | Medicinal chemistry (Shariqah (United Arab Emirates)) | Med Chem | 18 | 8 | 10.2174/1573406418666220221145500 | eng | 2,022 | null | null | null | null | null | [AIMS] The present study aimed at characterizing the impact of the presence or absence of fluorine atoms on the phenyl and benzopyran rings of 4-phenyl(thio)ureido-substituted 2,2- dimethylchromans on their ability to inhibit insulin release from pancreatic β-cells or to relax vascular smooth muscle cells. [METHODS] Mo... | 2; 2-Dimethylchromans; calcium channel blockers; fluorine atoms impact; insulin secretion; potassium channel openers; smooth muscle contractile activity | null | null | null | null | null |
35,189,677 | Obstructive fibrinous pseudomembrane tracheitis after double-lumen tube intubation -a case report. | Korean journal of anesthesiology | Korean J Anesthesiol | 75 | 4 | 10.4097/kja.21460 | eng | 2,022 | 8 | null | 2,022 | 2 | 22 | [BACKGROUND] Obstructive fibrinous pseudomembrane tracheitis (OFPT) is a rare complication of endotracheal intubation. [CASE] We describe the case of a 73-year-old woman who underwent short-term intubation for video-assisted thoracoscopic surgery and developed an acute life-threatening stridor two days after extubation... | Airway management; Airway obstruction; Respiratory insufficiency; Respiratory tract diseases; Tracheal stenosis; Tracheitis | 0.856 | 48 | Anesthesiology and Pain Medicine | Medicine | 2,022 |
35,189,455 | Deformation-based morphometry identifies deep brain structures protected by ocrelizumab. | NeuroImage. Clinical | Neuroimage Clin | 34 | null | 10.1016/j.nicl.2022.102959 | eng | 2,022 | null | null | 2,022 | 2 | 14 | [BACKGROUND] Despite advancements in treatments for multiple sclerosis, insidious disease progression remains an area of unmet medical need, for which atrophy-based biomarkers may help better characterize the progressive biology. [METHODS] We developed and applied a method of longitudinal deformation-based morphometry ... | Biomarkers; Brain atrophy; Deformation-based morphometry; Multiple sclerosis; Ocrelizumab | null | null | null | null | null |
35,189,011 | A nationwide survey of Italian Centers for Cognitive Disorders and Dementia on the provision of care for international migrants. | European journal of neurology | Eur J Neurol | 29 | 7 | 10.1111/ene.15297 | eng | 2,022 | 7 | null | 2,022 | 3 | 10 | [BACKGROUND] More than 500,000 dementia cases can be estimated among migrants living in Europe. There is the need to collect "real world" data on the preparedness of healthcare services to support the inclusion of migrants in the public health response to dementia. The present study aimed (i) to estimate the number of ... | culture-sensitivity; dementia; diversity; migration | 1.554 | 151 | Neurology; Neurology | Medicine; Neuroscience | 2,022 |
35,188,804 | Utility of Perioperative Measurement of Cell-Free DNA and Circulating Tumor DNA in Informing the Prognosis of GI Cancers: A Systematic Review. | JCO precision oncology | JCO Precis Oncol | 6 | null | 10.1200/PO.21.00337 | eng | 2,022 | 2 | null | null | null | null | [PURPOSE] Current surveillance imaging and tumor markers lack sensitivity for the early detection of recurrence in GI cancers. This study critically evaluates the current literature on the role of sequential measurement of circulating tumor DNA (ctDNA) before and after curative resection in informing recurrence. [METHO... | null | 2.208 | 56 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,188,715 | IgG Anti-Citrullinated Protein Antibody Variable Domain Glycosylation Increases Before the Onset of Rheumatoid Arthritis and Stabilizes Thereafter: A Cross-Sectional Study Encompassing ~1,500 Samples. | Arthritis rheumatology (Hoboken, N.J.) | Arthritis Rheumatol | 74 | 7 | 10.1002/art.42098 | eng | 2,022 | 7 | null | 2,022 | 5 | 28 | [OBJECTIVE] The autoimmune response in rheumatoid arthritis (RA) is marked by the presence of anti-citrullinated protein antibodies (ACPAs). A notable feature of IgG ACPA is the abundant expression of N-linked glycans in the variable domain. However, the presence of ACPA variable domain glycosylation (VDG) across disea... | null | null | null | null | null | null |
35,188,340 | Pattern and predictors of sites of relapse in neuroblastoma: A report from the International Neuroblastoma Risk Group (INRG) project. | Pediatric blood cancer | Pediatr Blood Cancer | 69 | 9 | 10.1002/pbc.29616 | eng | 2,022 | 9 | null | 2,022 | 2 | 21 | [PURPOSE] We sought to analyze biologic, clinical, and prognostic differences according to pattern of failure at the time of first relapse in neuroblastoma. [PATIENTS AND METHODS] Children 21 years diagnosed with neuroblastoma between 1989 and 2017 with known site of first relapse (isolated local vs. distant only vs. c... | neuroblastoma; pattern of failure; relapse; survival | null | null | null | null | null |
35,188,210 | Risk Factors for the Development of IgE-Mediated Food Allergy in Preschool Children with Asthma. | Journal of tropical pediatrics | J Trop Pediatr | 68 | 2 | 10.1093/tropej/fmac008 | eng | 2,022 | 2 | 3 | null | null | null | [BACKGROUND] Food allergy is a component of the atopic march and may have effects on asthma. This study aimed to evaluate the risk factors for confirmed immunoglobulin E-mediated food allergies and their impact on the clinical picture in preschool children with asthma. [METHODS] Clinical history and allergic assessment... | Food allergy; asthma; preschool children | 0.522 | 62 | Medicine; Pediatrics, Perinatology and Child Health; Infectious Diseases | Medicine | 2,022 |
35,187,992 | Financial incentives to improve re-engagement in HIV care: results from a randomized pilot study. | AIDS care | AIDS Care | 35 | 7 | 10.1080/09540121.2022.2041164 | eng | 2,023 | 7 | null | 2,022 | 2 | 19 | [OBJECTIVE] Determine the feasibility, acceptability, and preliminary effectiveness of financial incentives to motivate re-engagement in HIV care in Shinyanga, Tanzania. [METHODS] Out-of-care people living with HIV (PLHIV) were identified from medical records in four clinics and home-based care providers (HBCs) from Ap... | HIV care continuum; adherence; retention | null | null | null | null | null |
35,187,565 | Outpatient parenteral antimicrobial therapy (OPAT) in the UK: findings from the BSAC National Outcomes Registry (2015-19). | The Journal of antimicrobial chemotherapy | J Antimicrob Chemother | 77 | 5 | 10.1093/jac/dkac047 | eng | 2,022 | 4 | 27 | null | null | null | [BACKGROUND] Reporting of outpatient parenteral antimicrobial therapy (OPAT) outcomes with national benchmarking is key to informing service development and supporting quality improvement. [OBJECTIVES] To analyse and report on data collected by the BSAC OPAT National Outcomes Registry from 2015 to 2019. [METHODS] Quart... | null | 1.382 | 229 | Infectious Diseases; Microbiology; Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,022 |
35,187,192 | Perceptions of Telemedicine and Costs Incurred by a Visit to a General Infectious Diseases Clinic: A Survey. | Open forum infectious diseases | Open Forum Infect Dis | 9 | 3 | 10.1093/ofid/ofab661 | eng | 2,022 | 3 | null | 2,022 | 1 | 22 | [BACKGROUND] The costs of attending in-person general infectious diseases clinics and preferences for visit type (telemedicine vs in-person) are not well known. We aimed to measure the time-related, monetary, social, and societal costs associated with travel to an in-person clinic visit and to assess patients' preferen... | infectious diseases consultation; social capital expenditure; telemedicine; telemedicine cost; telemedicine environmental impact | 1.498 | 74 | Infectious Diseases; Oncology | Medicine | 2,022 |
35,186,841 | Higher Risk of Mortality and Virologic Failure in HIV-Infected Patients With High Viral Load at Antiretroviral Therapy Initiation: An Observational Cohort Study in Chongqing, China. | Frontiers in public health | Front Public Health | 10 | null | 10.3389/fpubh.2022.800839 | eng | 2,022 | null | null | 2,022 | 2 | 3 | [BACKGROUND] Viral load (VL) is a strong predictor of human immunodeficiency virus (HIV) disease progression. The aim of this study was to evaluate the effect of high baseline VL on antiretroviral therapy (ART) outcomes among HIV-infected patients. [METHODS] This retrospective study observed HIV-infected patients who h... | HIV/AIDS; antiretroviral therapy; baseline; risk; viral load | 1.125 | 119 | Public Health, Environmental and Occupational Health | Medicine | 2,022 |
35,186,708 | Risk Analysis of Severe Thrombocytopenia in Nasopharyngeal Carcinoma During Concurrent Radio-Chemotherapy. | Frontiers in oncology | Front Oncol | 11 | null | 10.3389/fonc.2021.754624 | eng | 2,021 | null | null | 2,022 | 2 | 2 | [OBJECTIVE] To explore the risk factors and predictive indexes of severe thrombocytopenia during concurrent radio-chemotherapy of nasopharyngeal carcinomas. [METHODS] Retrospective analysis was performed from the hospitalized patients with nasopharyngeal carcinoma from August 2014 to July 2017, and induction chemothera... | concurrent radio-chemotherapy; nasopharyngeal carcinoma; platelet depletion; predictive factors; risk factors | 1.291 | 156 | Oncology; Cancer Research | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
35,186,686 | Comparison of fundus fluorescein angiography and fundus photography grading criteria for early diabetic retinopathy. | International journal of ophthalmology | Int J Ophthalmol | 15 | 2 | 10.18240/ijo.2022.02.11 | eng | 2,022 | null | null | 2,022 | 2 | 18 | [AIM] To compare the assessment outcomes of the characteristics of mild to moderate non-proliferative diabetic retinopathy (NPDR) established by fundus photography and fundus fluorescein angiography (FFA). [METHODS] The fundus photos and FFA results of 260 patients with diabetes mellitus were reviewed. Diabetic retinop... | diabetic retinopathy; fundus fluorescein angiography; grading criteria | 0.565 | 48 | Ophthalmology | Medicine | 2,022 |
35,186,124 | Stereotactic radiotherapy for soft tissue and bone sarcomas: real-world evidence. | Therapeutic advances in medical oncology | Ther Adv Med Oncol | 14 | null | 10.1177/17588359211070646 | eng | 2,022 | null | null | 2,022 | 2 | 14 | [INTRODUCTION] Selected patients with locally advanced or metastatic soft tissue and bone sarcomas (STBS) may benefit from intensive local treatment, such as stereotactic radiotherapy (SRT). This study aimed to summarize the utilization and outcomes of SRT in STBS and to identify predictive factors for progression and ... | image-guided radiation therapy; individualized medicine; metastases; rare diseases; sarcoma; stereotactic body radiotherapy; targeted radiotherapy | 1.514 | 74 | Oncology | Medicine | 2,022 |
35,186,107 | Efficacy and Safety of Lianhua Qingke Tablets in the Treatment of Mild and Common-Type COVID-19: A Randomized, Controlled, Multicenter Clinical Study. | Evidence-based complementary and alternative medicine : eCAM | Evid Based Complement Alternat Med | 2022 | null | 10.1155/2022/8733598 | eng | 2,022 | null | null | 2,022 | 2 | 10 | [BACKGROUND] Lianhua Qingke (LH) tablets is an effective traditional Chinese medicine against various viral infections, especially in relieving coughing. However, its effects on COVID-19 are unknown. [METHODS] To examine the therapeutic effectiveness of LH tablets in COVID-19 patients with mild and common types, a rand... | null | null | null | null | null | null |
35,185,866 | Determination of CSF GFAP, CCN5, and vWF Levels Enhances the Diagnostic Accuracy of Clinically Defined MS From Non-MS Patients With CSF Oligoclonal Bands. | Frontiers in immunology | Front Immunol | 12 | null | 10.3389/fimmu.2021.811351 | eng | 2,021 | null | null | 2,022 | 2 | 4 | [BACKGROUND] Inclusion of cerebrospinal fluid (CSF) oligoclonal IgG bands (OCGB) in the revised McDonald criteria increases the sensitivity of diagnosis when dissemination in time (DIT) cannot be proven. While OCGB negative patients are unlikely to develop clinically definite (CD) MS, OCGB positivity may lead to an err... | diagnosis; metabolomics (OMICS); multiple sclerosis (MS); oligoclonal band; proteomics | 2.331 | 259 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,021 |
35,185,771 | Dual Antiplatelet Therapy in Patients With Minor Stroke Receiving Intravenous Thrombolysis. | Frontiers in neurology | Front Neurol | 13 | null | 10.3389/fneur.2022.819896 | eng | 2,022 | null | null | 2,022 | 2 | 4 | [INTRODUCTION] Concern over the potential severe bleeding risk of dual antiplatelet therapy for patients with minor stroke after intravenous thrombolysis (IVT) leads to different antiplatelet strategies in the secondary prevention of stroke. Our aim was to investigate the effect of dual antiplatelet therapy on patients... | dual antiplatelet; intravenous thrombolysis; ischemic stroke; minor stroke; secondary prevention | 0.978 | 118 | Neurology; Neurology | Medicine; Neuroscience | 2,022 |
35,185,758 | TTR Gly83Arg Mutation: Beyond Familial Vitreous Amyloidosis. | Frontiers in neurology | Front Neurol | 12 | null | 10.3389/fneur.2021.821003 | eng | 2,021 | null | null | 2,022 | 2 | 3 | [BACKGROUND] Gly83Arg variation is a type of TTR mutation specific to the Chinese population. Patients of hereditary transthyretin amyloidosis (ATTR) with Gly83Arg variation predominantly present with blurred vision and most of these cases are reported by ophthalmologists. There is currently no systematic assessment of... | China; Gly83Arg; extraocular symptoms; ocular symptoms; transthyretin amyloidosis | 1.027 | 118 | Neurology; Neurology | Medicine; Neuroscience | 2,021 |
35,185,745 | Association Between Lipid Accumulation Product and Cognitive Function in Hypertensive Patients With Normal Weight: Insight From the China H-type Hypertension Registry Study. | Frontiers in neurology | Front Neurol | 12 | null | 10.3389/fneur.2021.732757 | eng | 2,021 | null | null | 2,022 | 2 | 3 | [BACKGROUND] Hypertension is a major cardiovascular risk factor for cognitive impairment. Lipid accumulation product (LAP), an index that represents fat overaccumulation in the body, has been shown to be associated with cardiovascular disease. Nevertheless, the relationship between LAP and cognitive function in hyperte... | cognitive function; hypertension; lipid accumulation product; mini-mental state examination; normal-weight | 1.027 | 118 | Neurology; Neurology | Medicine; Neuroscience | 2,021 |
35,185,520 | Predicted Cognitive Conversion in Guiding Early Decision-Tailoring on Patients With Cognitive Impairment. | Frontiers in aging neuroscience | Front Aging Neurosci | 13 | null | 10.3389/fnagi.2021.813923 | eng | 2,021 | null | null | 2,022 | 2 | 2 | [BACKGROUND] Cognitive decline is the most dominant and patient-oriented symptom during the development of Alzheimer's disease (AD) and mild cognitive impairment (MCI). This study was designed to test the feasibility of hybrid convolutional neural networks and long-short-term memory (CNN-LSTM) modeling driven early dec... | cognitive conversion; decision-tailoring; deep learning; medical treatment reassignment; mild cognitive impairment | 1.324 | 135 | Aging; Cognitive Neuroscience | Biochemistry, Genetics and Molecular Biology; Neuroscience | 2,021 |
35,185,418 | Effect of Ultraviolet B Irradiation on Melanin Content Accompanied by the Activation of p62/GATA4-Mediated Premature Senescence in HaCaT Cells. | Dose-response : a publication of International Hormesis Society | Dose Response | 20 | 1 | 10.1177/15593258221075321 | eng | 2,022 | null | null | 2,022 | 2 | 14 | [OBJECTIVE] To explore the effect and mechanism of ultraviolet B (UVB) on melanin synthesis and premature senescence in human immortalized keratinocytes (HaCaT) cells. [METHODS] HaCaT cells were irradiated with 0, 20, 50, 80, 100, 150, and 200 mJ/cm[2] of UVB. NaOH method was used for melanin content assay, cellular ty... | GATA4; UVB; melanin content; p62; premature senescence; tyrosinase (TYR) | 0.472 | 51 | Chemical Health and Safety; Health, Toxicology and Mutagenesis; Public Health, Environmental and Occupational Health; Toxicology | Chemical Engineering; Environmental Science; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,022 |
35,185,320 | Common Ground: Primary Care and Specialty Clinicians' Perceptions of E-Consults in the Veterans Health Administration. | Federal practitioner : for the health care professionals of the VA, DoD, and PHS | Fed Pract | 39 | 1 | 10.12788/fp.0214 | eng | 2,022 | 1 | null | 2,022 | 1 | 12 | [OBJECTIVE] The US Department of Veterans Affairs (VA) introduced electronic consultation (e-consult) to increase access to specialty care. The objective of this study was to understand perceptions of e-consults that may be relevant to increasing adoption in the VA. [METHODS] Deductive and inductive content analysis of... | null | null | null | null | null | null |
35,184,988 | A 20-year experience in cadaveric pediatric en bloc kidney transplantation in adult recipients. | Actas urologicas espanolas | Actas Urol Esp (Engl Ed) | 46 | 2 | 10.1016/j.acuroe.2021.09.003 | eng | 2,022 | 3 | null | 2,022 | 2 | 17 | [BACKGROUND AND OBJECTIVES] En bloc kidney transplantation (EBKT) from pediatric donors into adult recipients increases the donor pool. However, this surgical procedure is not widely performed in many transplant centers. To evaluate the long-term outcomes of EBKT from pediatric donors into adult recipients in a single ... | Adult recipient; En bloc kidney transplant; Kidney transplantation; Pediatric donor; Receptor adulto; Trasplante renal; Trasplante renal en bloque | 0.308 | 30 | Urology | Medicine | 2,022 |
35,184,956 | Intra-articular injection versus interscalene brachial plexus block for acute-phase postoperative pain management after arthroscopic shoulder surgery. | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association | J Orthop Sci | 28 | 3 | 10.1016/j.jos.2022.01.004 | eng | 2,023 | 5 | null | 2,022 | 2 | 17 | [BACKGROUND] The minimally invasive approach of arthroscopic shoulder surgery is beneficial; however, for optimal outcomes, perioperative pain management is essential. This cross-sectional study aimed to examine the analgesic effectiveness of intra-articular injection (IA) versus interscalene brachial plexus block (ISP... | null | 0.531 | 86 | Orthopedics and Sports Medicine; Surgery | Medicine | 2,023 |
35,184,672 | Global contact lens prescribing 2000-2020. | Clinical experimental optometry | Clin Exp Optom | 105 | 3 | 10.1080/08164622.2022.2033604 | eng | 2,022 | 4 | null | 2,022 | 2 | 20 | [CLINICAL RELEVANCE] Contact lens prescribing data serve as a benchmark for eye care clinicians in assessing their own prescribing patterns and provide useful contextual information for researchers and the contact lens industry. [PURPOSE] To document global trends in contact lens prescribing during the first two decade... | Contact lenses; extended wear; global; hydrogel; international; longitudinal survey; multifocal; prescribing; rigid; silicone; soft; toric; trends | null | null | null | null | null |
35,184,419 | Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma. | Cancer communications (London, England) | Cancer Commun (Lond) | 42 | 4 | 10.1002/cac2.12275 | eng | 2,022 | 4 | null | 2,022 | 2 | 20 | [BACKGROUND] Resistance to ferroptosis, a regulated cell death caused by iron-dependent excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma (LUAD). Intracellular antioxidant systems are required for protection against ferroptosis. The purpose of the present study was to investigat... | N-arachidonoyl taurine; RNA-protein interaction; circRNA_101093; desensitization; exosome; ferroptosis; lipid peroxidation; lung adenocarcinoma; poly-unsaturated fatty acid; taurine | null | null | null | null | null |
35,184,183 | Circulating Proteome and Progression of Type 2 Diabetes. | The Journal of clinical endocrinology and metabolism | J Clin Endocrinol Metab | 107 | 6 | 10.1210/clinem/dgac098 | eng | 2,022 | 5 | 17 | null | null | null | [CONTEXT] Circulating proteomes may provide intervention targets for type 2 diabetes (T2D). [OBJECTIVE] We aimed to identify proteomic biomarkers associated with incident T2D and assess its joint effect with dietary or lifestyle factors on the T2D risk. [METHODS] We established 2 nested case-control studies for inciden... | circulating proteome; prospective study; red meat; type 2 diabetes | 1.776 | 400 | Biochemistry; Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,184,161 | The Association Between Severity of Radiographic Knee OA and Recurrent Falls in Middle and Older Aged Adults: The Osteoarthritis Initiative. | The journals of gerontology. Series A, Biological sciences and medical sciences | J Gerontol A Biol Sci Med Sci | 78 | 1 | 10.1093/gerona/glac050 | eng | 2,023 | 1 | 26 | null | null | null | [BACKGROUND] Knee osteoarthritis (KOA) is the most prevalent type of OA and a leading cause of disability in the United States. Falls are a major public health concern in older adults. Our aim was to examine how the severity of radiographic KOA affects recurrent falls in a cohort of middle-aged and older individuals en... | Falls; Osteoarthritis; Physical function | 1.285 | 230 | Geriatrics and Gerontology; Aging | Biochemistry, Genetics and Molecular Biology; Medicine | 2,023 |
35,184,098 | Identifying Gait Pathology after ACL Reconstruction Using Temporal Characteristics of Kinetics and Electromyography. | Medicine and science in sports and exercise | Med Sci Sports Exerc | 54 | 6 | 10.1249/MSS.0000000000002881 | eng | 2,022 | 6 | 1 | 2,022 | 2 | 18 | [PURPOSE] Asymmetrical gait mechanics after anterior cruciate ligament reconstruction (ACLR) are associated with the development of posttraumatic knee osteoarthritis. Current measures of gait mechanics have focused heavily on peak magnitudes of knee kinematics, kinetics, and joint contact forces but have seldom conside... | null | 1.734 | 271 | Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science | Health Professions; Medicine | 2,022 |
35,183,710 | A Postmortem Analysis of Polyethylene Damage and Periprosthetic Tissue in Rotating Platform and Fixed Bearing Tibial Inserts. | The Journal of arthroplasty | J Arthroplasty | 37 | 6 | 10.1016/j.arth.2022.02.051 | eng | 2,022 | 6 | null | 2,022 | 2 | 18 | [BACKGROUND] Mobile bearing designs are intended to reduce wear, but mixed results were reported from retrieval analyses. Postmortem evaluation (PM) provides the opportunity to assess polyethylene damage in successful implants. We compared damage patterns, MRI presentation, and histology between mobile-bearing and fixe... | bearing; fixed bearing; knee; polyethylene; polyethylene damage; postmortem; rotating platform; tibia | 2.028 | 171 | Orthopedics and Sports Medicine | Medicine | 2,022 |
35,183,690 | Khasianine ameliorates psoriasis-like skin inflammation and represses TNF-α/NF-κB axis mediated transactivation of IL-17A and IL-33 in keratinocytes. | Journal of ethnopharmacology | J Ethnopharmacol | 292 | null | 10.1016/j.jep.2022.115124 | eng | 2,022 | 6 | 28 | 2,022 | 2 | 17 | [ETHNO-PHARMACOLOGICAL RELEVANCE] Khasianine is recently identified as a bioactive compound from Solanum nigrum L. (SNL) which is a traditional Chinese herb (named LongKui in China) and has been clinically applied for treating psoriasis in China but with limited knowledge about the active ingredients. [AIM OF THE STUDY... | Inflammation; Khasianine; Psoriasis; Transactivation | 0.833 | 243 | Drug Discovery; Pharmacology | Pharmacology, Toxicology and Pharmaceutics | 2,022 |
35,183,257 | Effects of service-wide support on regularity of alcohol screening of clients in Australian Aboriginal and Torres Strait Islander Community Controlled Health Services: a cluster randomised trial. | Addiction science clinical practice | Addict Sci Clin Pract | 17 | 1 | 10.1186/s13722-022-00294-6 | eng | 2,022 | 2 | 19 | 2,022 | 2 | 19 | [BACKGROUND] We have previously shown that service-wide support can increase the odds of alcohol screening in any 2-month period in a cluster randomized trial of service-wide support to Aboriginal and Torres Strait Islander Community Controlled Health Services (ACCHS). Here we report an exploratory analysis on whether ... | AUDIT-C; Aboriginal; Alcohol; Alcohol screening; Continuous quality improvement; Indigenous; Primary care; Screening patterns; Torres Strait Islander; Training and support | null | null | null | null | null |
35,183,105 | Expiratory central airway collapse during positive pressure ventilation: a case report. | BMC anesthesiology | BMC Anesthesiol | 22 | 1 | 10.1186/s12871-022-01591-y | eng | 2,022 | 2 | 19 | 2,022 | 2 | 19 | [BACKGROUND] Physiologic narrowing of the central airway occurs during expiration. Conditions in which this narrowing becomes excessive are referred to as expiratory central airway collapse. Expiratory central airway collapse is usually managed by applying positive pressure to the airways, which acts as a pneumatic ste... | Airway obstruction; Case report; Desaturation; Expiratory central airway collapse | 0.609 | 58 | Anesthesiology and Pain Medicine | Medicine | 2,022 |
35,183,030 | Effects of Sarcopenia on Postoperative Outcomes in Patients Who Underwent Gastrectomy for Gastric Cancer. | The Journal of surgical research | J Surg Res | 274 | null | 10.1016/j.jss.2021.12.051 | eng | 2,022 | 6 | null | 2,022 | 2 | 16 | [BACKGROUND] The relationship between sarcopenia and postoperative outcomes in patients with gastric cancer remains controversial. This study aimed to investigate the impact of sarcopenia on short-term outcomes after surgery for gastric cancer. [METHODS] Patients who underwent surgical treatment for gastric cancer were... | Complications; Gastrectomy; Gastric cancer; Muscle strength; Sarcopenia | 0.785 | 131 | Surgery | Medicine | 2,022 |
35,182,316 | Sonographic normal values for the cross-sectional area of the ulnar nerve: a systematic review and meta-analysis. | Journal of ultrasound | J Ultrasound | 26 | 1 | 10.1007/s40477-022-00661-8 | eng | 2,023 | 3 | null | 2,022 | 2 | 19 | [PURPOSE] Nerve size is a commonly used sonographic parameter when assessing suspected entrapment of the ulnar nerve. We aimed to create a robust set of normal values, based on a critical review of published normal values. [METHODS] We performed a systematic evaluation of studies on normal ulnar nerve sizes, identified... | Cross-sectional area; Normal values; Reference values; Ulnar nerve; Ultrasound | 0.379 | 41 | Internal Medicine; Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,023 |
35,182,251 | Optimal lymph-node dissection for pancreatic tail cancer. | Surgery today | Surg Today | 52 | 9 | 10.1007/s00595-022-02463-1 | eng | 2,022 | 9 | null | 2,022 | 2 | 18 | [PURPOSE] The optimal range of lymph-node dissection for pancreatic tail cancer remains unclear. We investigated the location and frequency of lymph-node metastases to identify the correct range of lymph-node dissection for pancreatic tail cancer. [METHODS] We analyzed clinical data retrospectively, on patients who und... | Distal pancreatectomy; Pancreatic ductal carcinoma; Tumor metastasis | 0.753 | 77 | Surgery; Medicine | Medicine | 2,022 |
35,182,155 | Perceived racial discrimination and eating habits: a systematic review and conceptual models. | Nutrition reviews | Nutr Rev | 80 | 7 | 10.1093/nutrit/nuac001 | eng | 2,022 | 6 | 9 | null | null | null | [CONTEXT] There is no systematic review on the relationship between racial discrimination and eating habits. [OBJECTIVE] A systematic review was conducted to synthesize evidence on the association between perceived racial discrimination (PRD) and eating habits. A conceptual model was developed to depict the most common... | conceptual model; eating habits; racism; social epidemiology; systematic review | 1.521 | 185 | Medicine; Nutrition and Dietetics | Medicine; Nursing | 2,022 |
35,182,135 | SIMULATION OF APPROPRIATE RHEOVASOGRAPHIC INDICATORS OF THE FEMUR IN VOLLEYBALL PLAYERS OF ECTOMORPHIC SOMATOTYPE DEPENDING ON ANTHROPOMETRIC FEATURES. | Wiadomosci lekarskie (Warsaw, Poland : 1960) | Wiad Lek | 75 | 1 pt 2 | null | eng | 2,022 | null | null | null | null | null | [OBJECTIVE] The aim of the study was to build regression models of rheovasographic parameters of the femur in volleyball players of ectomorphic somatotype depending on the features of anthropometric indicators. [PATIENTS AND METHODS] Materials and methods: 113 volleyball players of a high level of sportsmanship of adol... | anthropometric parameters; regression models; rheovasography of thigh; volleyball | null | null | null | null | null |
35,182,131 | SURGICAL SITE INFECTION AFTER LAPAROSCOPIC HYSTERECTOMY FOR BENIGN GYNECOLOGICAL DISEASE IN UKRAINE. | Wiadomosci lekarskie (Warsaw, Poland : 1960) | Wiad Lek | 75 | 1 pt 2 | null | eng | 2,022 | null | null | null | null | null | [OBJECTIVE] The aim: To obtain the first estimates of the current incidence, and risk factors for Surgical Site Infection (SSI) after laparoscopic hysterectomy, and antimicrobial resistance of responsible pathogens in Ukraine. [PATIENTS AND METHODS] Materials and methods: We performed a multicenter prospective cohort s... | benign gynecological disease; laparoscopic hysterectomy; risk factors; surgical site infection; antimicrobial resistance | null | null | null | null | null |
35,182,129 | CLINICAL PECULIARITIES AND PATHOGENETIC DETERMINANTS OF DEVELOPMENT AND PROGRESSION OF CHRONIC PULMONARY HEART WITH ARTERIAL HYPERTENSION. | Wiadomosci lekarskie (Warsaw, Poland : 1960) | Wiad Lek | 75 | 1 pt 2 | null | eng | 2,022 | null | null | null | null | null | [OBJECTIVE] The aim: To investigate the clinical and pathogenetic peculiarities of formation and course of CCP and the relationship between clinical, hemodynamic and neurohumoral factors of comorbidity development in COPD combined with arterial hypertension (AH). [PATIENTS AND METHODS] Materials and methods: The object... | apoptosis; chronic cor pulmonale; inflammation; mitogenic growth factors; neurohumoral activation | null | null | null | null | null |
35,182,124 | INFLUENCE OF INTERVAL NORMOBARIC HYPOXYTHERAPY ON THE PROCESSES OF ISCHEMIC PRECONDITIONING IN THE MYOCARDIUM OF PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. | Wiadomosci lekarskie (Warsaw, Poland : 1960) | Wiad Lek | 75 | 1 pt 2 | null | eng | 2,022 | null | null | null | null | null | [OBJECTIVE] The aim: Determination of cardioprotective effect of interval normobaric hypoxia in medical rehabilitation of patients with COPD. [PATIENTS AND METHODS] Materials and methods: 123 patients with COPD who received basic drug therapy were examined and were divided into 2 groups. Patients of the main group (93 ... | COPD; cardioprotection; interval normobaric hypoxytherapy; the phenomenon of ischemic preconditioning | null | null | null | null | null |
35,181,886 | Construction of artificial intelligence system of carpal bone age for Chinese children based on China-05 standard. | Medical physics | Med Phys | 49 | 5 | 10.1002/mp.15554 | eng | 2,022 | 5 | null | 2,022 | 3 | 1 | [PURPOSE] The purpose of this study is to construct an automatic carpal bone age evaluation system for Chinese children based on TW3-C Carpal method by deep learning and to evaluate the accuracies in test set and clinical test set. [METHODS] A total of 8184 radiographs of Chinese Han healthy children (2-14 years old) w... | AI-China-05 Carpal; TW3-C Carpal; bone age; deep learning | 1.072 | 218 | Biophysics; Medicine; Radiology, Nuclear Medicine and Imaging | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,181,870 | Effectiveness of a Uniquely Designed Oral Appliance on Obstructive Sleep Apnea Control: A Pilot Study. | European journal of dentistry | Eur J Dent | 16 | 3 | 10.1055/s-0041-1735933 | eng | 2,022 | 7 | null | 2,022 | 2 | 18 | [OBJECTIVES] Obstructive sleep apnea is an inflammatory, chronic, and evolutive disease often needing adequate treatment and follow-up. The oral appliance (OA) is an accepted alternative therapy for obstructive sleep apnea (OSA) control. Due to greater adherence, OA with mandibular advancement (OAm) is being recommende... | null | 0.654 | 53 | Dentistry | Dentistry | 2,022 |
35,181,539 | Off-label usage of RhBMP-2 in posterior cervical fusion is not associated with early increased complication rate and has similar clinical outcomes. | The spine journal : official journal of the North American Spine Society | Spine J | 22 | 7 | 10.1016/j.spinee.2022.02.005 | eng | 2,022 | 7 | null | 2,022 | 2 | 16 | [BACKGROUND CONTEXT] Arthrodesis is important for the success of posterior cervical fusion (PCF), however, there exists limited data regarding the safety and efficacy of bone morphogenic protein (BMP) in PCF. [PURPOSE] The primary objective was to evaluate early postoperative complications associated with BMP in PCF an... | Allograft; Arthrodesis; BMP; Bone morphogenic protein; Myelopathy; Patient-reported outcome; Posterior cervical fusion; Posterior cervical surgery | 1.562 | 143 | Neurology; Orthopedics and Sports Medicine; Surgery | Medicine | 2,022 |
35,180,833 | Associations between hyper-polypharmacy and potentially inappropriate prescribing with clinical and functional outcomes in older adults. | Expert opinion on drug safety | Expert Opin Drug Saf | 21 | 7 | 10.1080/14740338.2022.2044786 | eng | 2,022 | 7 | null | 2,022 | 3 | 1 | [BACKGROUND] Hyper-polypharmacy and potentially inappropriate prescribing (PIP) are common among older inpatients. This study investigated associations between hyper-polypharmacy and PIP with clinical and functional outcomes in older adults at 3-months after hospital discharge. [RESEARCH DESIGN AND METHOD] At discharge... | Functional status; inappropriate prescribing; medication therapy management; mortality; patient readmission; polypharmacy | 0.773 | 96 | Medicine; Pharmacology | Medicine | 2,022 |
35,180,717 | Prevalence of Private and Public Health Insurance Among Transgender and Gender Diverse Adults. | Medical care | Med Care | 60 | 4 | 10.1097/MLR.0000000000001693 | eng | 2,022 | 4 | 1 | null | null | null | [BACKGROUND] Little is known about how health insurance payer types differ between transgender and gender diverse (TGD) people and cisgender people. Much of what is known about insurance coverage among TGD adults has been based on research from claims and electronic health record data, which excludes individuals who ha... | null | 1.293 | 207 | Public Health, Environmental and Occupational Health | Medicine | 2,022 |
35,179,643 | Efficacy of medial rectus plication versus resection for exotropia: a meta-analysis. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie | Graefes Arch Clin Exp Ophthalmol | 260 | 7 | 10.1007/s00417-022-05589-7 | eng | 2,022 | 7 | null | 2,022 | 2 | 18 | [OBJECTIVE] To compare the outcomes of medial rectus plication and medial rectus resection procedures in the treatment of exotropia. [METHODS] Articles from Pubmed, EMBASE, Web of Science, and Cochrane Library databases until July 2021 with a minimum follow-up period of 1 month were retrieved. No restriction on languag... | Exotropia; Meta-analysis; Outcome; Surgical treatment | null | null | null | null | null |
35,179,257 | Replication of gene polymorphisms associated with periodontitis-related traits in an elderly cohort: the Washington Heights/Inwood Community Aging Project Ancillary Study of Oral Health. | Journal of clinical periodontology | J Clin Periodontol | 49 | 5 | 10.1111/jcpe.13605 | eng | 2,022 | 5 | null | 2,022 | 3 | 16 | [AIM] We sought to replicate findings from published genome-wide association studies (GWAS), linking specific candidate gene loci with periodontitis-related clinical/microbial traits. [MATERIALS AND METHODS] In the published GWAS, a total of 2196 single nucleotide polymorphisms associated with periodontitis-related tra... | epidemiology; genome-wide association study; multi-ethnic; periodontal disease; replication | 2.407 | 187 | Periodontics | Dentistry | 2,022 |
35,179,050 | Improvement in arterial enhancement using diluted injection of contrast medium in CT angiography. | Acta radiologica (Stockholm, Sweden : 1987) | Acta Radiol | 64 | 2 | 10.1177/02841851221077400 | eng | 2,023 | 2 | null | 2,022 | 2 | 18 | [BACKGROUND] Arterial enhancement after contrast injection affects the quality of computed tomography angiography (CTA) images. [PURPOSE] To evaluate whether the dilution of contrast medium (CM) for CTA increases arterial enhancement after the adjustment of iodine concentration as per the patient's body weight (BW). [M... | Computed tomography angiography; arterial enhancement; body weight; diluted contrast medium injection; iodine concentration | 0.429 | 82 | Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging | Health Professions; Medicine | 2,023 |
35,179,007 | Patient-reported outcome measures (PROMs) and palliative-care clinician reported outcomes (ClinROs) mutually improve pain and other symptoms assessment of hospitalized cancer-patients. | Scandinavian journal of pain | Scand J Pain | 22 | 3 | 10.1515/sjpain-2021-0162 | eng | 2,022 | 7 | 26 | 2,022 | 2 | 17 | [OBJECTIVES] Patients with malignant diseases are known to have a high symptom burden including pain, and insufficient treatment of pain in this population has been frequently documented. To promote the integration of specialized palliative care and hematology and oncology, this study investigated disease, treatment, a... | cancer pain; neuralgia; pain measurement; patient reported outcome measures; quality of life; symptom assessment | 0.534 | 39 | Anesthesiology and Pain Medicine; Neurology | Medicine | 2,022 |
35,178,719 | Quality and nutritional value of cookies enriched with plant-based protein preparations. | Journal of the science of food and agriculture | J Sci Food Agric | 102 | 11 | 10.1002/jsfa.11821 | eng | 2,022 | 8 | 30 | 2,022 | 3 | 7 | [BACKGROUND] The objective of the study was to determine the effect of addition of plant-based protein preparations in cookie recipes on the quality and nutritional value of the obtained products. Wheat flour was replaced by 10%, 20% or 30% of pea, hemp seed, pumpkin and sunflower seed preparations. Baked cookies were ... | amino acid analysis; chemical composition; cookies; hemp seeds; protein pea; pumpkin seeds; sunflower seeds | null | null | null | null | null |
35,178,548 | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection by Intranasal or Intratesticular Route Induces Testicular Damage. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | Clin Infect Dis | 75 | 1 | 10.1093/cid/ciac142 | eng | 2,022 | 8 | 24 | null | null | null | [BACKGROUND] The role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the pathogenesis of testicular damage is uncertain. [METHODS] We investigated the virological, pathological, and immunological changes in testes of hamsters challenged by wild-type SARS-CoV-2 and its variants with intranasal or dir... | COVID-19; SARS-CoV-2; coronavirus; hamster; testicle | 3.995 | 398 | Infectious Diseases; Microbiology | Medicine | 2,022 |
35,178,459 | Crucial Genes in Aortic Dissection Identified by Weighted Gene Coexpression Network Analysis. | Journal of immunology research | J Immunol Res | 2022 | null | 10.1155/2022/7585149 | eng | 2,022 | null | null | 2,022 | 2 | 7 | [BACKGROUND] Aortic dissection (AD) is a lethal vascular disease with high mortality and morbidity. Though AD clinical pathology is well understood, its molecular mechanisms remain unclear. Specifically, gene expression profiling helps illustrate the potential mechanism of aortic dissection in terms of gene regulation ... | null | 0.899 | 122 | Medicine; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,022 |
35,177,907 | Reduced Peripheral Nerve Conduction Velocity is Associated with Alzheimer's Disease: A Cross-Sectional Study from China. | Neuropsychiatric disease and treatment | Neuropsychiatr Dis Treat | 18 | null | 10.2147/NDT.S349005 | eng | 2,022 | null | null | 2,022 | 2 | 11 | [PURPOSE] Elderly individuals with degenerative diseases of the central nervous system are more likely to develop peripheral neuropathy; however, research is limited as to whether the decline in peripheral nerve conduction can be used as a biomarker of Alzheimer's disease (AD). [PATIENTS AND METHODS] This study enrolle... | biomarker; cognition; mild cognitive impairment; peripheral motor nerve velocity | 0.789 | 98 | Psychiatry and Mental Health; Biological Psychiatry | Medicine; Neuroscience | 2,022 |
35,177,906 | A Nomogram for Individualized Prediction of Stress-Related Gastrointestinal Bleeding in Critically Ill Patients with Primary Intracerebral Hemorrhage. | Neuropsychiatric disease and treatment | Neuropsychiatr Dis Treat | 18 | null | 10.2147/NDT.S342861 | eng | 2,022 | null | null | 2,022 | 2 | 9 | [PURPOSE] To establish and validate a nomogram model for predicting stress-related gastrointestinal bleeding in critically ill patients with primary intracerebral hemorrhage. [PATIENTS AND METHODS] From January 2018 to March 2021, we conducted a hospital-based study by screening eligible patients with acute intracerebr... | decision curve analysis; intracerebral hemorrhage; nomogram; prediction; stress-related gastrointestinal bleeding | 0.789 | 98 | Psychiatry and Mental Health; Biological Psychiatry | Medicine; Neuroscience | 2,022 |
35,177,561 | Prognostic Utility of Procalcitonin, Presepsin, and the VACO Index for Predicting 30-day Mortality in Hospitalized COVID-19 Patients. | Annals of laboratory medicine | Ann Lab Med | 42 | 4 | 10.3343/alm.2022.42.4.406 | eng | 2,022 | 7 | 1 | null | null | null | [BACKGROUND] Biomarkers and clinical indices have been investigated for predicting mortality in patients with coronavirus disease (COVID-19). We explored the prognostic utility of procalcitonin (PCT), presepsin, and the Veterans Health Administration COVID-19 (VACO) index for predicting 30-day-mortality in COVID-19 pat... | 30-Day mortality; COVID-19; Prediction; Presepsin; Procalcitonin; VACO index | null | null | null | null | null |
35,177,560 | Digital Morphology Analyzer Sysmex DI-60 vs. Manual Counting for White Blood Cell Differentials in Leukopenic Samples: A Comparative Assessment of Risk and Turnaround Time. | Annals of laboratory medicine | Ann Lab Med | 42 | 4 | 10.3343/alm.2022.42.4.398 | eng | 2,022 | 7 | 1 | null | null | null | [BACKGROUND] Digital morphology (DM) analyzers are increasingly being used for white blood cell (WBC) differentials. We assessed the laboratory efficiency of the Sysmex DI-60 system (DI-60; Sysmex, Kobe, Japan) in comparison with manual counting in leukopenic samples. [METHODS] In total, 40 peripheral blood smear sampl... | DI-60; Laboratory efficiency; Leukopenia; Risk; Turnaround time; WBC differential | null | null | null | null | null |
35,177,526 | Hemivertebra Resection and Spinal Arthrodesis by Single-Stage Posterior Approach in Congenital Scoliosis and Kyphoscoliosis: Results at 9.6 Years Mean Follow-up. | International journal of spine surgery | Int J Spine Surg | 16 | 1 | 10.14444/8188 | eng | 2,022 | 2 | null | 2,022 | 2 | 17 | [BACKGROUND] Congenital kyphoscoliosis due to hemivertebra is generally treated surgically because of high risk of curve progression and high risk of nervous system complications. Modern posterior access surgical techniques, including total hemivertebra resection, can completely correct deformity without additional ant... | congenital scoliosis; hemivertebra resection; posterior vertebral arthrodesis | 0.591 | 40 | Orthopedics and Sports Medicine; Surgery | Medicine | 2,022 |
35,177,263 | Starr frame-assisted minimally invasive internal fixation for pelvic fractures: Simultaneous anterior and posterior ring stability. | Injury | Injury | 54 Suppl 2 | null | 10.1016/j.injury.2022.02.025 | eng | 2,023 | 4 | null | 2,022 | 2 | 10 | [OBJECTIVE] We aimed to investigate the surgical techniques, efficacy, and safety of Starr frame-assisted minimally invasive internal fixation for simultaneous anterior and posterior ring stability in pelvic fractures. [METHODS] The clinical data of 22 patients with anterior and posterior pelvic ring injuries who under... | INFIX; Minimally invasive internal fixation; Pelvic fracture; Starr frame | 0.728 | 151 | Emergency Medicine; Surgery; Orthopedics and Sports Medicine | Medicine | 2,023 |
35,177,249 | Population-Based Trends in Amputations and Revascularizations for Peripheral Artery Disease From 1990 to 2009. | Mayo Clinic proceedings | Mayo Clin Proc | 97 | 5 | 10.1016/j.mayocp.2021.10.021 | eng | 2,022 | 5 | null | 2,022 | 2 | 15 | [OBJECTIVE] To determine trends in amputations and revascularizations for peripheral artery disease (PAD) in a well-defined population. [METHODS] A population-based cohort study of Olmsted County, Minnesota, residents with PAD undergoing amputation or revascularization was conducted between January 1, 1990, and Decembe... | null | 2.056 | 221 | Medicine | Medicine | 2,022 |
35,177,040 | Understanding how context and culture in six communities can shape implementation of a complex intervention: a comparative case study. | BMC health services research | BMC Health Serv Res | 22 | 1 | 10.1186/s12913-022-07615-0 | eng | 2,022 | 2 | 17 | 2,022 | 2 | 17 | [BACKGROUND] Contextual factors can act as barriers or facilitators to scaling-up health care interventions, but there is limited understanding of how context and local culture can lead to differences in implementation of complex interventions with multiple stakeholder groups. This study aimed to explore and describe t... | Case study; Interprofessional health care teams; Primary care; Qualitative research; Volunteers | 0.964 | 157 | Health Policy | Medicine | 2,022 |
35,177,019 | Adapting and testing a brief intervention to reduce maternal anxiety during pregnancy (ACORN): report of a feasibility randomized controlled trial. | BMC psychiatry | BMC Psychiatry | 22 | 1 | 10.1186/s12888-022-03737-1 | eng | 2,022 | 2 | 17 | 2,022 | 2 | 17 | [BACKGROUND] We investigated the acceptability and feasibility of a new brief intervention for maternal prenatal anxiety within maternity services in London and Exeter, UK. [METHODS] One hundred fourteen pregnant individuals attending their 12-week scan at a prenatal clinic with elevated symptoms of anxiety (GAD-7 scor... | Antenatal; Anxiety; Pregnancy; Randomised controlled trial; Therapy | 1.291 | 151 | Psychiatry and Mental Health | Medicine | 2,022 |
35,177,015 | Coexistence of diabetes mellitus and pre-existing cardiovascular disease and mortality in Chinese patients on peritoneal dialysis. | BMC nephrology | BMC Nephrol | 23 | 1 | 10.1186/s12882-022-02702-0 | eng | 2,022 | 2 | 17 | 2,022 | 2 | 17 | [BACKGROUND] Little is known about the association between the coexistence of diabetes mellitus (DM) and pre-existing cardiovascular disease (CVD) and mortality in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). [METHODS] A retrospective cohort study of 2939 Chinese incident CAPD patients was cond... | Cardiovascular disease; Diabetes mellitus; Mortality; Peritoneal dialysis | 0.746 | 83 | Nephrology | Medicine | 2,022 |
35,176,991 | Fangchinoline Inhibited Proliferation of Neoplastic B-lymphoid Cells and Alleviated Sjögren's Syndrome-like Responses in NOD/Ltj Mice via the Akt/mTOR Pathway. | Current molecular pharmacology | Curr Mol Pharmacol | 15 | 7 | 10.2174/1874467215666220217103233 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Fangchinoline is a bisbenzylisoquinoline alkaloid extracted from Stephania tetrandra S. Moore that is conventionally used as an analgesic, antirheumatic, and antihypertensive drug in China. However, the application of Fanchinoline in Sjögren syndrome (SS) remains unreported. [OBJECTIVE] This study aimed to... | Akt/mTOR pathway; B cells; Fangchinoline; LY294002; lymphocytic focus; wild-type ICR mice | null | null | null | null | null |
35,176,883 | Assessing the Accuracy of International Classification of Diseases (ICD) Coding for Delirium. | Journal of applied gerontology : the official journal of the Southern Gerontological Society | J Appl Gerontol | 41 | 5 | 10.1177/07334648211067526 | eng | 2,022 | 5 | null | 2,022 | 2 | 17 | [OBJECTIVE] We assessed the accuracy of the ICD-10 code for delirium (F05) and its relationship with delirium discharge summary documentation. [METHODS] We performed a retrospective chart review at three academic hospitals. The Chart-based Delirium Identification Instrument (CHART-DEL) was used to identify 108 hospital... | ICD-10; aged; delirium; hospital discharge; medical documentation; medical record | null | null | null | null | null |
35,176,838 | Ocular Dominance in Open-angle Glaucoma: The Shifting Trend Depending on Stage of the Disease. | Korean journal of ophthalmology : KJO | Korean J Ophthalmol | 36 | 3 | 10.3341/kjo.2021.0165 | eng | 2,022 | 6 | null | 2,022 | 2 | 18 | [PURPOSE] To investigate the characteristics and distribution of ocular dominance in primary open-angle glaucoma eyes. In addition, we tried to catch any trend of ocular dominance according to the stage of disease. [METHODS] Two hundred participants with bilateral open-angle glaucoma underwent ocular dominant testing b... | Glaucoma; Ocular dominance; Primary open angle glaucoma | 0.425 | 41 | Ophthalmology | Medicine | 2,022 |
35,176,659 | Timing of pericardiocentesis and clinical outcomes: Is earlier pericardiocentesis better? | The American journal of emergency medicine | Am J Emerg Med | 54 | null | 10.1016/j.ajem.2022.01.062 | eng | 2,022 | 4 | null | 2,022 | 2 | 3 | [BACKGROUND] Pericardial tamponade is critical clinical diagnosis that requires prompt management and intervention. However, it is unknown if early pericardiocentesis is associated with better or worse patient outcomes. [METHODS] A retrospective chart review was performed on all emergency department patients from two l... | Pericardial tamponade; Pericardiocentesis; Point-of-care ultrasound (POCUS); Transthoracic echocardiography (TTE) | 0.88 | 114 | Emergency Medicine; Medicine | Medicine | 2,022 |
35,176,658 | Evaluation of emergency service nurses' patient handover and affecting factors: A descriptive study. | International emergency nursing | Int Emerg Nurs | 61 | null | 10.1016/j.ienj.2022.101154 | eng | 2,022 | 3 | null | 2,022 | 2 | 14 | [AIM] The aim of the study was to determine the patient handover efficacy level of emergency room nurses and the influencing factors. [METHOD] This descriptive, cross-sectional study was completed with (n = 120) emergency room nurses of two different state hospitals from April 26 to May 26, 2021. The "Nurses descriptiv... | Emergency nursing; Nursing; Patient handover; Patient safety | 0.569 | 54 | Emergency Nursing | Nursing | 2,022 |
35,175,782 | SPARC, a Novel Regulator of Vascular Cell Function in Pulmonary Hypertension. | Circulation | Circulation | 145 | 12 | 10.1161/CIRCULATIONAHA.121.057001 | eng | 2,022 | 3 | 22 | 2,022 | 2 | 17 | [BACKGROUND] Pulmonary hypertension (PH) is a life-threatening disease, characterized by excessive pulmonary vascular remodeling, leading to elevated pulmonary arterial pressure and right heart hypertrophy. PH can be caused by chronic hypoxia, leading to hyper-proliferation of pulmonary arterial smooth muscle cells (PA... | apoptosis; endothelial cells; hypertension, pulmonary; hypoxia; myocytes, smooth muscle | 7.8 | 691 | Cardiology and Cardiovascular Medicine; Physiology | Medicine | 2,022 |
35,175,362 | Return to work after injury in Hong Kong: prospective multi-center cohort study. | European journal of trauma and emergency surgery : official publication of the European Trauma Society | Eur J Trauma Emerg Surg | 48 | 4 | 10.1007/s00068-022-01899-x | eng | 2,022 | 8 | null | 2,022 | 2 | 17 | [PURPOSE] Trauma remains a major cause of morbidity and disability worldwide; however, reliable data on the health status of an urban Asian population after injury are scarce. The aim was to evaluate 1-year post-trauma return to work (RTW) status in Hong Kong. [METHODS] This was a prospective, multi-center cohort study... | Patient-reported outcome measures; Return to work; Trauma center; Wounds and injuries | 0.565 | 54 | Critical Care and Intensive Care Medicine; Emergency Medicine; Orthopedics and Sports Medicine; Surgery | Medicine | 2,022 |
35,175,345 | Use of Lipid-, Blood Pressure-, and Glucose-Lowering Pharmacotherapy in Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease. | JAMA network open | JAMA Netw Open | 5 | 2 | 10.1001/jamanetworkopen.2021.48030 | eng | 2,022 | 2 | 1 | 2,022 | 2 | 1 | [IMPORTANCE] Based on contemporary estimates in the US, evidence-based therapies for cardiovascular risk reduction are generally underused among patients with type 2 diabetes and atherosclerotic cardiovascular disease (ASCVD). [OBJECTIVE] To determine the use of evidence-based cardiovascular preventive therapies in a b... | null | 4.108 | 154 | Medicine | Medicine | 2,022 |
35,175,316 | Effect of Capecitabine Maintenance Therapy Plus Best Supportive Care vs Best Supportive Care Alone on Progression-Free Survival Among Patients With Newly Diagnosed Metastatic Nasopharyngeal Carcinoma Who Had Received Induction Chemotherapy: A Phase 3 Randomized Clinical Trial. | JAMA oncology | JAMA Oncol | 8 | 4 | 10.1001/jamaoncol.2021.7366 | eng | 2,022 | 4 | 1 | null | null | null | [IMPORTANCE] Capecitabine maintenance therapy improves survival outcomes in various cancer types, but data are limited on the efficacy and safety of capecitabine maintenance therapy in metastatic nasopharyngeal carcinoma (NPC). [OBJECTIVE] To investigate the efficacy and safety of capecitabine maintenance therapy in me... | null | null | null | null | null | null |
35,175,214 | Refinement of a Parent-Child Shared Asthma Management Mobile Health App: Human-Centered Design Study. | JMIR pediatrics and parenting | JMIR Pediatr Parent | 5 | 1 | 10.2196/34117 | eng | 2,022 | 2 | 17 | 2,022 | 2 | 17 | [BACKGROUND] The school-age years, approximately ages 7 through 11, represent a natural transition when children begin assuming some responsibility for their asthma management. Previously, we designed a theoretically derived, tailored parent-child shared asthma management mobile health app prototype, Improving Asthma C... | asthma; family health informatics; mHealth; participatory design; prototype; school-age children; usability | 0.778 | 22 | Pediatrics, Perinatology and Child Health; Biomedical Engineering; Health Informatics | Engineering; Medicine | 2,022 |
35,175,065 | Dynamic interplay of cognitive functioning and depressive symptoms in patients with Parkinson's disease. | Neuropsychology | Neuropsychology | 36 | 4 | 10.1037/neu0000795 | eng | 2,022 | 5 | null | 2,022 | 2 | 17 | [OBJECTIVE] We examine the trajectories of and the dynamic interplay between cognitive functioning and depressive symptoms in patients with Parkinson's disease (PD) in comparison to healthy controls (HC) from an intraindividual perspective. [METHOD] The DeNoPa study is a single-center, observational, longitudinal study... | null | 0.9 | 150 | Neuropsychology and Physiological Psychology | Psychology | 2,022 |
35,174,728 | A New Framework for Investigating the Biological Basis of Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 5]: Mechanical Stress, Vulnerability and Time. | Global spine journal | Global Spine J | 12 | 1_suppl | 10.1177/21925682211057546 | eng | 2,022 | 2 | null | null | null | null | [STUDY DESIGN] Literature Review (Narrative). [OBJECTIVE] To propose a new framework, to support the investigation and understanding of the pathobiology of DCM, AO Spine RECODE-DCM research priority number 5. [METHODS] Degenerative cervical myelopathy is a common and disabling spinal cord disorder. In this perspective,... | cervical; degeneration; disability; disc herniation; myelopathy; ossification posterior longitudinal ligament; questionnaire; recovery; spondylosis; spondylotic; stenosis | 1.043 | 59 | Neurology; Orthopedics and Sports Medicine; Surgery | Medicine | 2,022 |
35,174,652 | Modified Medial Collateral Ligament Indentation Technique in Total Knee Arthroplasty with Severe Type II Valgus Deformity. | Orthopaedic surgery | Orthop Surg | 14 | 4 | 10.1111/os.13230 | eng | 2,022 | 4 | null | 2,022 | 2 | 17 | [OBJECTIVE] To explore the feasibility and clinical efficacy of a modified medial collateral ligament indentation technique in total knee arthroplasty (TKA) with severe type II valgus deformity. [METHODS] Consecutive patients with Krackow type II valgus deformity 20° who underwent a primary unilateral TKA between May 2... | Arthroplasty; Constrained condylar knee; Medial collateral ligament; Medial indentation; Valgus | 0.634 | 46 | Orthopedics and Sports Medicine; Surgery | Medicine | 2,022 |
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