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35,398,743 | Survival, functional, and quality of life outcomes between total glossectomy with and without total laryngectomy: A narrative review. | American journal of otolaryngology | Am J Otolaryngol | 43 | 3 | 10.1016/j.amjoto.2022.103440 | eng | 2,022 | null | null | 2,022 | 4 | 5 | [BACKGROUND] A total glossectomy (TG) may be required for advanced tongue tumors. TG with total laryngectomy (TGL) may be indicated in some cases with tumor extension into the larynx or high risk of aspiration. Total glossectomy with laryngeal preservation (TGLP) may preserve phonation ability relative to TGL, yet TGLP... | Head and neck cancer; Outcomes; Survival; Total glossectomy; Total laryngectomy | null | null | null | null | null |
35,398,585 | Impact of "natural" cesarean delivery on peripartum blood loss: a randomized controlled trial. | American journal of obstetrics gynecology MFM | Am J Obstet Gynecol MFM | 4 | 4 | 10.1016/j.ajogmf.2022.100642 | eng | 2,022 | 7 | null | 2,022 | 4 | 8 | [BACKGROUND] Early skin-to-skin contact after vaginal delivery increases milk production and may increase oxytocin release, leading to a reduction in the rate of postpartum hemorrhage. [OBJECTIVE] This study aimed to examine the effect of "natural" cesarean deliveries on perioperative maternal blood loss. [STUDY DESIGN... | blood loss; breastfeeding; natural cesarean delivery; oxytocin level; skin-to-skin contact | null | null | null | null | null |
35,398,029 | Predictive RNA profiles for early and very early spontaneous preterm birth. | American journal of obstetrics and gynecology | Am J Obstet Gynecol | 227 | 1 | 10.1016/j.ajog.2022.04.002 | eng | 2,022 | 7 | null | 2,022 | 4 | 6 | [BACKGROUND] Spontaneous preterm birth remains the main driver of childhood morbidity and mortality. Because of an incomplete understanding of the molecular pathways that result in spontaneous preterm birth, accurate predictive markers and target therapeutics remain elusive. [OBJECTIVE] This study sought to determine i... | Biomarker; cell-free RNA; cervical remodeling; midtrimester loss; pregnancy; preterm labor; spontaneous preterm birth; transcriptome | 3.068 | 274 | Obstetrics and Gynecology | Medicine | 2,022 |
35,397,553 | Engineering cascade biocatalysis in whole cells for bottom-up synthesis of cello-oligosaccharides: flux control over three enzymatic steps enables soluble production. | Microbial cell factories | Microb Cell Fact | 21 | 1 | 10.1186/s12934-022-01781-w | eng | 2,022 | 4 | 9 | 2,022 | 4 | 9 | [BACKGROUND] Soluble cello-oligosaccharides (COS, β-1,4-D-gluco-oligosaccharides with degree of polymerization DP 2-6) have been receiving increased attention in different industrial sectors, from food and feed to cosmetics. Development of large-scale COS applications requires cost-effective technologies for their prod... | Activity ratios; Cello-oligosaccharides; Co-expression; Multi-enzymatic cascade; Whole-cell catalyst | 1.091 | 134 | Applied Microbiology and Biotechnology; Bioengineering; Biotechnology | Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Immunology and Microbiology | 2,022 |
35,397,513 | Difference between medial and lateral tibia plateau in the coronal plane: importance of preoperative evaluation for medial unicompartmental knee arthroplasty. | BMC musculoskeletal disorders | BMC Musculoskelet Disord | 23 | 1 | 10.1186/s12891-022-05298-6 | eng | 2,022 | 4 | 9 | 2,022 | 4 | 9 | [BACKGROUND] Setting bone cutting levels for different joint line orientations of the medial and lateral tibia plateaus in individual patients is not clear. We aimed to evaluate the difference between joint line orientation of the medial and lateral tibia plateaus relative to the horizontal line of mechanical axis of t... | Joint line orientation; Knee osteoarthritis; Medial unicompartmental knee arthroplasty; Total knee replacement | 0.716 | 131 | Orthopedics and Sports Medicine; Rheumatology | Medicine | 2,022 |
35,397,501 | Real-world characteristics, treatment experiences and corticosteroid utilisation of patients treated with tofacitinib for moderate to severe ulcerative colitis. | BMC gastroenterology | BMC Gastroenterol | 22 | 1 | 10.1186/s12876-022-02215-y | eng | 2,022 | 4 | 9 | 2,022 | 4 | 9 | [BACKGROUND] Tofacitinib is an oral, small molecule JAK inhibitor for the treatment of UC. We aimed to describe the real-world treatment experience and corticosteroid utilisation of patients treated with tofacitinib in a US claims database. [METHODS] Patients with a UC diagnosis who initiated tofacitinib, vedolizumab o... | Adherence; Oral corticosteroid; Small molecule Janus kinase inhibitor; Tofacitinib; Tumour necrosis factor inhibitor (TNFi); Ulcerative colitis; Vedolizumab | 0.759 | 99 | Gastroenterology; Medicine | Medicine | 2,022 |
35,397,475 | STAT3 is a biologically relevant therapeutic target in H3K27M-mutant diffuse midline glioma. | Neuro-oncology | Neuro Oncol | 24 | 10 | 10.1093/neuonc/noac093 | eng | 2,022 | 10 | 3 | null | null | null | [BACKGROUND] H3K27M-mutant diffuse midline glioma (DMG) is a lethal brain tumor that usually occurs in children. Despite advances in our understanding of its underlying biology, efficacious therapies are severely lacking. [METHODS] We screened a library of drugs either FDA-approved or in clinical trial using a library ... | DIPG; DMG; H3K27M; STAT3; midline glioma | 4.833 | 178 | Cancer Research; Neurology; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,397,473 | Adult brain tumors in Sub-Saharan Africa: A scoping review. | Neuro-oncology | Neuro Oncol | 24 | 10 | 10.1093/neuonc/noac098 | eng | 2,022 | 10 | 3 | null | null | null | [BACKGROUND] Sub-Saharan African (SSA) neuro-oncologists report high workloads and challenges in delivering evidence-based care; however, these reports contrast with modeled estimates of adult neuro-oncology disease burden in the region. This scoping review aimed to better understand the reasons for this discrepancy by... | Sub-Saharan Africa; epidemiology; global neurosurgery; neuro-oncology; scoping review | 4.833 | 178 | Cancer Research; Neurology; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,397,293 | Non-invasive ways of administering insulin. | Diabetes metabolic syndrome | Diabetes Metab Syndr | 16 | 4 | 10.1016/j.dsx.2022.102478 | eng | 2,022 | 4 | null | 2,022 | 4 | 2 | [BACKGROUND AND AIMS] Insulin is crucial in the management of diabetes. However, requires injection which itself comes with some challenges. Alternative delivery routes have been investigated that are needle-free, with enhanced absorption and bioavailability. This review presents novel non-invasive insulin administrati... | Absorption; Bioavailability; Delivery routes; Diabetes; Hypoglycemia; Insulin | null | null | null | null | null |
35,415,542 | Biomechanical Evaluation of Opponensplasty for Low Median Palsy: A Cadaver Study. | Journal of hand surgery global online | J Hand Surg Glob Online | 3 | 2 | 10.1016/j.jhsg.2020.11.002 | eng | 2,021 | 3 | null | 2,021 | 1 | 17 | [PURPOSE] Impaired thumb opposition associated with advanced carpal tunnel syndrome may be treated by opponensplasty at the time of open carpal tunnel release. However, it is unclear which opponensplasty technique achieves the greatest functional improvement. This study aimed to compare the biomechanics of thumb opposi... | Burkhalter; Carpal tunnel syndrome; Median nerve; Opponensplasty; Tendon transfer | 0.204 | 11 | Rehabilitation; Surgery; Orthopedics and Sports Medicine | Medicine | 2,021 |
35,456,216 | Safety and Efficacy of Short Daily Hemodialysis with Physidia S[3] System: Clinical Performance Assessment during the Training Period. | Journal of clinical medicine | J Clin Med | 11 | 8 | 10.3390/jcm11082123 | eng | 2,022 | 4 | 11 | 2,022 | 4 | 11 | [BACKGROUND] A growing body of scientific evidence indicates that clinical outcomes of hemodialysis patients can be improved with short daily dialysis treatment. Current in-center hemodialysis machines do not fulfill the requirements needed for self-care home hemodialysis (HHD) treatment. In line with the reviviscence ... | end-stage kidney disease; hemodialysis; home therapy; portable artificial kidney | 0.935 | 132 | Medicine | Medicine | 2,022 |
35,455,559 | Orthorexia and Eating Disorders in Adolescents and Young Adults: A Systematic Review. | Children (Basel, Switzerland) | Children (Basel) | 9 | 4 | 10.3390/children9040514 | eng | 2,022 | 4 | 6 | 2,022 | 4 | 6 | [BACKGROUND] In recent years a new term in the field of eating behaviors has emerged, namely "orthorexia". This behavior is associated with significant dietary restrictions and omission of food groups. The aim of the present study is to estimate the possible correlations between orthorexia and eating disorders in young... | adolescents; anorexia; bulimia; eating disorders; mental health; orthorexia; young adults | 0.504 | 56 | Pediatrics, Perinatology and Child Health | Medicine | 2,022 |
35,453,585 | Immunogenicity, Effectiveness, and Safety of COVID-19 Vaccines in Rheumatic Patients: An Updated Systematic Review and Meta-Analysis. | Biomedicines | Biomedicines | 10 | 4 | 10.3390/biomedicines10040834 | eng | 2,022 | 4 | 1 | 2,022 | 4 | 1 | [BACKGROUND] Vaccination is one of the most important measures worldwide to halt the spread of the corona virus disease 2019 (COVID-19). However, the efficacy and safety of these vaccines in rheumatic patients are not well explored. Therefore, we conducted a systematic review and meta-analysis. [METHODS] We performed a... | COVID-19 vaccine; adverse events; flare; immunogenicity; rheumatic disease; safety | 0.897 | 85 | Medicine; Biochemistry, Genetics and Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,453,114 | Assessing the differences in operative and patient-reported outcomes between lateral approaches for lumbar fusion: a systematic review and indirect meta-analysis. | Journal of neurosurgery. Spine | J Neurosurg Spine | 37 | 4 | 10.3171/2022.2.SPINE211164 | eng | 2,022 | 10 | 1 | 2,022 | 4 | 22 | [OBJECTIVE] Anterior-to-psoas lumbar interbody fusion (ATP-LIF), more commonly referred to as oblique lateral interbody fusion, and lateral transpsoas lumbar interbody fusion (LTP-LIF), also known as extreme lateral interbody fusion, are the two commonly used lateral approaches for performing a lumbar fusion procedure.... | ATP; LLIF; LTP; OLIF; XLIF; anterior to psoas; lateral lumbar interbody fusion; lateral to psoas; transpsoas lumbar interbody fusion; oblique lumbar interbody fusion | null | null | null | null | null |
35,453,111 | Early surgical versus endovascular repair of ruptured blood-blister aneurysm of the internal carotid artery: a single-center 20-year experience. | Journal of neurosurgery | J Neurosurg | 137 | 6 | 10.3171/2022.3.JNS2216 | eng | 2,022 | 12 | 1 | 2,022 | 4 | 22 | [OBJECTIVE] Early repair of ruptured blood-blister aneurysms (BBAs) of the internal carotid artery (ICA) remains challenging. Although both surgical and endovascular therapies have been established, their relative superiority remains debated. The authors assessed their single-center experience and compared early decons... | blood-blister aneurysms; cerebral aneurysm; endovascular neurosurgery; endovascular treatment; subarachnoid hemorrhage; surgery; vascular disorders | 1.138 | 244 | Neurology; Surgery | Medicine | 2,022 |
35,453,059 | Lung ultrasound findings following COVID-19 hospitalization: A prospective longitudinal cohort study. | Respiratory medicine | Respir Med | 197 | null | 10.1016/j.rmed.2022.106826 | eng | 2,022 | 6 | null | 2,022 | 4 | 2 | [BACKGROUND] Lung ultrasound (LUS) is a useful tool for diagnosis and monitoring in patients with active COVID-19-infection. However, less is known about the changes in LUS findings after a hospitalization for COVID-19. [METHODS] In a prospective, longitudinal study in patients with COVID-19 enrolled from non-ICU hospi... | COVID-19; Longitudinal follow-up; Lung ultrasound | 1.334 | 145 | Pulmonary and Respiratory Medicine | Medicine | 2,022 |
35,452,601 | Comparison of Tensile Properties and Knot Security of Surgical Sutures: An In Vitro Mechanical Study. | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons | J Oral Maxillofac Surg | 80 | 7 | 10.1016/j.joms.2022.03.014 | eng | 2,022 | 7 | null | 2,022 | 3 | 26 | [PURPOSE] Studies on the mechanical properties and knot security of smaller sutures used in oral and maxillofacial surgery are limited. The objective of this study is to measure the tensile properties and knot security depending on the suture materials, knotting techniques, and number of throws using 5-0 sized sutures.... | null | 0.649 | 147 | Oral Surgery; Otorhinolaryngology; Surgery | Dentistry; Medicine | 2,022 |
35,452,556 | A parsimonious and comprehensive screening tool for adult health behaviors. | Public health nursing (Boston, Mass.) | Public Health Nurs | 39 | 5 | 10.1111/phn.13085 | eng | 2,022 | 9 | null | 2,022 | 4 | 22 | [BACKGROUND] A practical screening tool for early detection of unhealthy behaviors among adults to provide tailored care can have an important role in public health nursing. [PURPOSE] To develop a screening tool with valid psychometric properties for adult health behaviors (AHBs). [METHODS] A cross-sectional study was ... | adult health behaviors; confirmatory factor analysis; life satisfaction; public health nursing; screening tool | 0.697 | 63 | Nursing; Public Health, Environmental and Occupational Health | Medicine; Nursing | 2,022 |
35,452,417 | Therapeutic Effects of Curcumin on Osteoarthritis and Its Protection of Chondrocytes Through the Wnt/Β-Catenin Signaling Pathway. | Alternative therapies in health and medicine | Altern Ther Health Med | 28 | 5 | null | eng | 2,022 | 7 | null | null | null | null | [CONTEXT] Osteoarthritis (OA) is a high-incidence, chronic condition, with an extremely high prevalence among older adults. OA seriously compromises the normal living of OA patients, and it's imperative to find a novel therapy as soon as possible to improve their prognosis and life quality. [OBJECTIVE] The study intend... | null | 0.263 | 78 | Complementary and Alternative Medicine; Medicine | Medicine | 2,022 |
35,452,206 | Comparison of the Near Eye Tool for Refractive Assessment (NETRA) and non-cycloplegic subjective refraction. | BMJ open ophthalmology | BMJ Open Ophthalmol | 7 | 1 | 10.1136/bmjophth-2021-000851 | eng | 2,022 | null | null | 2,022 | 4 | 1 | [OBJECTIVE] The NETRA (Near Eye Tool for Refractive Assessment) is a smartphone-based refractive tool that allows for self-evaluation of refractive error. This study investigates the validity of the NETRA with and without cycloplegia to non-cycloplegic subjective refractions (SR). [METHODS AND ANALYSIS] Participants un... | optics and refraction; public health; telemedicine | 0.913 | 28 | Ophthalmology | Medicine | 2,022 |
35,451,734 | Cardiac Rehabilitation in Advanced aGE after PCI for acute coronary syndromes: predictors of exercise capacity improvement in the CR-AGE ACS study. | Aging clinical and experimental research | Aging Clin Exp Res | 34 | 9 | 10.1007/s40520-022-02130-y | eng | 2,022 | 9 | null | 2,022 | 4 | 22 | [BACKGROUND] The positive effect of cardiac rehabilitation (CR) on outcomes after acute coronary syndromes (ACS) is established. Nevertheless, enrollment rates into CR programs remain low, although ACS carry a high risk of functional decline particularly in the elderly. [AIM] We aimed to determine if a multidisciplinar... | Acute coronary syndrome; Cardiac rehabilitation; Elderly; Exercise capacity | 0.982 | 95 | Aging; Geriatrics and Gerontology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,450,869 | Continuous glucose monitoring demonstrates low risk of clinically significant hypoglycemia associated with sulphonylurea treatment in an African type 2 diabetes population: results from the OPTIMAL observational multicenter study. | BMJ open diabetes research care | BMJ Open Diabetes Res Care | 10 | 2 | 10.1136/bmjdrc-2021-002714 | eng | 2,022 | 4 | null | null | null | null | [INTRODUCTION] People living with diabetes in low-resource settings may be at increased hypoglycemia risk due to food insecurity and limited access to glucose monitoring. We aimed to assess hypoglycemia risk associated with sulphonylurea (SU) and insulin therapy in people living with type 2 diabetes in a low-resource s... | CGM; Developing Countries; Diabetes Mellitus, Type 2; Hypoglycemia | null | null | null | null | null |
35,450,753 | Prognostic and Predictive Role of PD-L1 Expression in Stage III Non-small Cell Lung Cancer Treated With Definitive Chemoradiation and Adjuvant Durvalumab. | International journal of radiation oncology, biology, physics | Int J Radiat Oncol Biol Phys | 113 | 4 | 10.1016/j.ijrobp.2022.03.015 | eng | 2,022 | 7 | 15 | 2,022 | 4 | 19 | [PURPOSE] It is unclear whether programmed death ligand 1 (PD-L1) expression is prognostic or predictive of immunotherapy benefit among patients with stage III non-small cell lung cancer (NSCLC) treated with definitive chemoradiation and adjuvant durvalumab. [METHODS AND MATERIALS] We determined pretreatment tumor PD-L... | null | 2.09 | 286 | Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging | Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy | 2,022 |
35,450,398 | Triple Cross-Linked Hyaluronic Acid Based on Tri-Hyal Technique Has More Durable Effect on Dermal Renewal. | Clinical, cosmetic and investigational dermatology | Clin Cosmet Investig Dermatol | 15 | null | 10.2147/CCID.S362785 | eng | 2,022 | null | null | 2,022 | 4 | 15 | [BACKGROUND] Hyaluronic acid (HA)-based fillers are applied to treat facial wrinkles and volume loss. Many efforts have been made to improve properties of HA to prolong the duration in aesthetic indications. A new cross-linking technique called "Tri-Hyal", could make HAs to achieve desired rheological characteristics. ... | ROS; autophagy; fibroblasts; senescence; skin rejuvenation | 0.624 | 59 | Dermatology | Medicine | 2,022 |
35,450,177 | Clinical outcome of orbital apex syndrome in COVID associated mucormycosis patients in a tertiary care hospital. | International journal of ophthalmology | Int J Ophthalmol | 15 | 4 | 10.18240/ijo.2022.04.01 | eng | 2,022 | null | null | 2,022 | 4 | 18 | [AIM] To share clinical pattern of presentation, the modalities of surgical intervention and the one month post-surgical outcome of rhino-orbito-mucormycosis (ROCM) cases. [METHODS] All COVID associated mucormycosis (CAM) patients underwent comprehensive multidisciplinary examination by ophthalmologist, otorhinolaryngo... | COVID associated mucormycosis; endoscopic paranasal sinus debridement; orbital apex syndrome; orbital exenteration; rhino-orbito-cerebral mucormycosis | 0.565 | 48 | Ophthalmology | Medicine | 2,022 |
35,450,075 | The Associations of rs1799724 and rs361525 With the Risk of Ankylosing Spondylitis Are Dependent on HLA-B27 Status in a Chinese Han Population. | Frontiers in immunology | Front Immunol | 13 | null | 10.3389/fimmu.2022.852326 | eng | 2,022 | null | null | 2,022 | 4 | 5 | [OBJECTIVES] Human leucocyte antigen B27 (HLA-B27) is an important biomarker for ankylosing spondylitis (AS). However, delay in the diagnosis of AS is still common in clinical practice. Several single nucleotide polymorphisms (SNPs) in the coding gene of tumor necrosis factor alpha (TNFα) have been reported to be AS su... | ankylosing spondylitis; early diagnosis; human leucocyte antigen B27; risk prediction; single nucleotide polymorphism; tumor necrosis factor alpha | 2.022 | 259 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,022 |
35,449,820 | Protective Effect and Potential Mechanism of the Traditional Chinese Medicine Shaoyao-Gancao Decoction on Ethanol-Induced Gastric Ulcers in Rats. | Evidence-based complementary and alternative medicine : eCAM | Evid Based Complement Alternat Med | 2022 | null | 10.1155/2022/3069089 | eng | 2,022 | null | null | 2,022 | 4 | 11 | [BACKGROUND] Shaoyao-Gancao decoction (SGD) is a classic prescription in traditional Chinese medicine. SGD is effective in the treatment of gastric and duodenal ulcers. However, the biological activity and possible mechanisms of SGD in the treatment of gastric ulcers have not been fully elucidated. The purpose of this ... | null | null | null | null | null | null |
35,449,105 | Key stakeholders' views, experiences and expectations of patient and public involvement in healthcare professions' education: a qualitative study. | BMC medical education | BMC Med Educ | 22 | 1 | 10.1186/s12909-022-03373-z | eng | 2,022 | 4 | 22 | 2,022 | 4 | 22 | [BACKGROUND] Patients and the public have an integral role in educating healthcare professionals. Authentic partnerships between higher education institutions and patients and the public are essential. This study examined key stakeholders' views, experiences and expectations of patient and public involvement (PPI) incl... | Health professions education; Patient Educator; Patient Partner; Patient and public involvement | 0.914 | 107 | Education; Medicine | Medicine; Social Sciences | 2,022 |
35,449,065 | Quadruple term gestation of quadri-chorionic quadri-amniotic pregnancy after artificial insemination: a case report. | Reproductive health | Reprod Health | 19 | 1 | 10.1186/s12978-022-01400-2 | eng | 2,022 | 4 | 21 | 2,022 | 4 | 21 | [BACKGROUND] To solve infertility, modern science has promoted assisted reproduction techniques such as in vitro fertilization, ovulation induction, and artificial insemination. Quadruple-type multiple pregnancies occur in 1 of every 500,000 pregnancies, and it is estimated that 90% occur due to assisted reproductive t... | Assisted reproductive techniques; Multiple pregnancy; Quadruplet | 1.093 | 84 | Obstetrics and Gynecology; Reproductive Medicine | Medicine | 2,022 |
35,449,057 | Changed health behavior improves subjective well-being and vice versa in a follow-up of 9 years. | Health and quality of life outcomes | Health Qual Life Outcomes | 20 | 1 | 10.1186/s12955-022-01972-4 | eng | 2,022 | 4 | 21 | 2,022 | 4 | 21 | [BACKGROUND] Previous research on health behavior and subjective well-being has mainly focused on interindividual differences or explored certain domains of health behavior. Good health behavior and subjective well-being at baseline can predict each other after a follow-up. In the present cohort study, we explored the ... | Follow-up; Health behavior; Health behavior change; Life satisfaction; Longitudinal; Subjective well-being | 0.993 | 144 | Medicine; Public Health, Environmental and Occupational Health | Medicine | 2,022 |
35,449,050 | Sociodemographic correlates of colorectal cancer screening completion among women adherent to mammography screening guidelines by place of birth. | BMC women's health | BMC Womens Health | 22 | 1 | 10.1186/s12905-022-01694-1 | eng | 2,022 | 4 | 21 | 2,022 | 4 | 21 | [INTRODUCTION] Colorectal cancer screening rates in the U.S. still fall short of national goals, while screening rates for other cancer sites, such as breast, remain high. Understanding characteristics associated with colorectal cancer screening among different groups of women adherent to breast cancer screening guidel... | Breast neoplasms; Colorectal neoplasms; Demography; Early detection of cancer; Female; Mass screening | 0.775 | 73 | Medicine; Obstetrics and Gynecology; Reproductive Medicine | Medicine | 2,022 |
35,449,018 | Clinical variation in the organization of clinical pathways in esophagogastric cancer, a mixed method multiple case study. | BMC health services research | BMC Health Serv Res | 22 | 1 | 10.1186/s12913-022-07845-2 | eng | 2,022 | 4 | 20 | 2,022 | 4 | 20 | [BACKGROUND] Among esophagogastric cancer patients, the probability of having undergone treatment with curative intent has been shown to vary, depending on the hospital of diagnosis. However, little is known about the factors that contribute to this variation. In this study, we sought to understand the organization of ... | Cancer medicine; Esophageal cancer; Gastric cancer; Variation in clinical pathways | 0.964 | 157 | Health Policy | Medicine | 2,022 |
35,448,976 | Development and validation of a prognostic nomogram for gallbladder cancer patients after surgery. | BMC gastroenterology | BMC Gastroenterol | 22 | 1 | 10.1186/s12876-022-02281-2 | eng | 2,022 | 4 | 21 | 2,022 | 4 | 21 | [BACKGROUND] Gallbladder cancer is associated with late diagnosis and poor prognosis. Current study aims to develop a prognostic nomogram for predicting survival of gallbladder cancer patients after surgery. [METHODS] Two large cohorts were included in this analysis. One consisted of 1753 gallbladder cancer patients fr... | Gallbladder cancer; Model; Nomogram; Prognosis | 0.759 | 99 | Gastroenterology; Medicine | Medicine | 2,022 |
35,448,052 | Radiographic and Histomorphologic Evaluation of the Maxillary Bone after Crestal Mini Sinus Lift Using Absorbable Collagen-Retrospective Evaluation. | Dentistry journal | Dent J (Basel) | 10 | 4 | 10.3390/dj10040058 | eng | 2,022 | 4 | 2 | 2,022 | 4 | 2 | [BACKGROUND] After tooth extraction, the alveolar bone loses volume in height and width over time, meaning that reconstructive procedures may be necessary to perform implant placement. In the maxilla, to increase the bone volume, a mini-invasive surgery, such as a sinus lift using the crestal approach, could be perform... | CBCT; bone histology; collagen; hyaluronic acid; mini sinus lift; radiographic evaluation | 0.536 | 41 | Dentistry | Dentistry | 2,022 |
35,447,742 | Validation of the LittlEARS[®] Questionnaire in Hearing Maltese-Speaking Children. | Audiology research | Audiol Res | 12 | 2 | 10.3390/audiolres12020022 | eng | 2,022 | 4 | 11 | 2,022 | 4 | 11 | [OBJECTIVES] To adapt the LittlEARS[®] Auditory Questionnaire into the Maltese language and evaluate the psychometric properties of the Maltese version of the questionnaire for hearing children. [METHODS] The English version of LittlEARS[®] Auditory Questionnaire was adapted into Maltese using a translation/back transl... | LittlEARS; Maltese; auditory questionnaire; hearing screening; normative assessment | 0.371 | 13 | Otorhinolaryngology; Podiatry | Health Professions; Medicine | 2,022 |
35,447,632 | School Closures in the United States and Severe Respiratory Illnesses in Children: A Normalized Nationwide Sample. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies | Pediatr Crit Care Med | 23 | 7 | 10.1097/PCC.0000000000002967 | eng | 2,022 | 7 | 1 | 2,022 | 4 | 21 | [OBJECTIVES] To determine the association between nationwide school closures and prevalence of common admission diagnoses in the pediatric critical care unit. [DESIGN] Retrospective cohort study. [SETTING] National database evaluation using the Virtual Pediatric Systems LLC database. [PATIENTS] All patients admitted to... | null | 1.42 | 111 | Critical Care and Intensive Care Medicine; Pediatrics, Perinatology and Child Health | Medicine | 2,022 |
35,447,547 | Comprehensive polyoxypregnane glycosides report in Caralluma quadrangula using UPLC-ESI-Q-TOF and their antioxidant effects in human plasma. | Biomedicine pharmacotherapy = Biomedecine pharmacotherapie | Biomed Pharmacother | 150 | null | 10.1016/j.biopha.2022.112954 | eng | 2,022 | 6 | null | 2,022 | 4 | 18 | [ETHNOPHARMACOLOGICAL RELEVANCE] Caralluma quadrangula (Forssk.) N.E.Br. (Syns: = Stapelia quadrangula Forssk. = Monolluma quadrangula Forssk.) is an indigenous member of the genus Caralluma and it is a rather common species on rocky hillsides in the southwestern part of Saudi Arabia. Several members of this genus have... | Antioxidant effect; Caralluma quadrangula; DFT; Polyoxypregnane glycosides | null | null | null | null | null |
35,447,399 | Maternal exposure to traffic-related ambient particles and risk of gestational diabetes mellitus with isolated fasting hyperglycaemia: A retrospective cohort study in Beijing, China. | International journal of hygiene and environmental health | Int J Hyg Environ Health | 242 | null | 10.1016/j.ijheh.2022.113973 | eng | 2,022 | 5 | null | 2,022 | 4 | 18 | [BACKGROUND] Ambient particles have been associated with gestational diabetes mellitus (GDM), however, no study has evaluated the effects of traffic-related ambient particles on the risks of GDM subgroups classified by oral glucose tolerance test (OGTT) values. [METHODS] A retrospective analysis was conducted among 24,... | Blood glucose level; Gestational diabetes mellitus; Particle number concentration; Positive matrix factorization; Traffic-related air pollution | 1.47 | 126 | Public Health, Environmental and Occupational Health | Medicine | 2,022 |
35,447,222 | Antidepressant medication use by patients accessing a national digital mental health service. | Journal of affective disorders | J Affect Disord | 308 | null | 10.1016/j.jad.2022.04.042 | eng | 2,022 | 7 | 1 | 2,022 | 4 | 18 | [BACKGROUND] Digital mental health services (DMHSs) provide psychological treatments via the internet or phone and are increasingly being offered as part of routine care. This study describes antidepressant (AD) medication use and treatment outcomes in a large sample of routine care patients accessing a DMHS. [METHODS]... | Antidepressant medication; Depression; Digital mental health; Service implementation; Service utilization; Telehealth | 1.988 | 245 | Clinical Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,022 |
35,447,200 | Bioinformatics analysis combined with experimental validation to explore the mechanism of XianLing GuBao capsule against osteoarthritis. | Journal of ethnopharmacology | J Ethnopharmacol | 294 | null | 10.1016/j.jep.2022.115292 | eng | 2,022 | 8 | 10 | 2,022 | 4 | 18 | [ETHNOPHARMACOLOGICAL RELEVANCE] XianLing GuBao Capsule (XLGB) is often used to treat osteoarthritis (OA), osteoporosis, fractures, and other musculoskeleton disorders. However, the molecular mechanism of XLGB for treating OA is still unclear. [AIM OF THE STUDY] This study set out to uncover the molecular mechanism und... | Bioinformatics analysis; MAPK pathway; Osteoarthritis; XianLing GuBao capsule | 0.833 | 243 | Drug Discovery; Pharmacology | Pharmacology, Toxicology and Pharmaceutics | 2,022 |
35,445,877 | Objective evaluation of changes in lens clarity after repeated injections of ranibizumab in patients with neovascular age-related macular degeneration. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie | Graefes Arch Clin Exp Ophthalmol | 260 | 9 | 10.1007/s00417-022-05668-9 | eng | 2,022 | 9 | null | 2,022 | 4 | 21 | [PURPOSE] To objectively evaluate changes in lens densitometry in eyes with neovascular age-related macular degeneration (n-AMD) treated with repeated intravitreal ranibizumab injections during a 12-month period and to compare the results with those in untreated healthy fellow eyes and healthy control eyes. [METHODS] I... | Cataract; Lens densitometry; Ranibizumab; Scheimpflug imaging | null | null | null | null | null |
35,445,818 | Impact of phosphorylation of heat shock protein 27 on the expression profile of periodontal ligament fibroblasts during mechanical strain. | Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie | J Orofac Orthop | 84 | Suppl 2 | 10.1007/s00056-022-00391-w | eng | 2,023 | 4 | null | 2,022 | 4 | 21 | [PURPOSE] Orthodontic tooth movement is a complex process involving the remodeling of extracellular matrix and bone as well as inflammatory processes. During orthodontic treatment, sterile inflammation and mechanical loading favor the production of receptor activator of NF-κB ligand (RANKL). Simultaneously, expression ... | Bone remodeling; Compressive forces; Heat shock proteins; Orthodontic tooth movement; Osteogenesis | null | null | null | null | null |
35,445,720 | Cost-effectiveness analyses of biologic and targeted synthetic disease-modifying anti-rheumatic diseases in patients with rheumatoid arthritis: Three approaches with a cohort simulation and real-world data. | Modern rheumatology | Mod Rheumatol | 33 | 2 | 10.1093/mr/roac038 | eng | 2,023 | 3 | 2 | null | null | null | [OBJECTIVE] To assess the cost-effectiveness of biologic and targeted synthetic disease-modifying anti-rheumatic drugs (b/tsDMARDs) in rheumatoid arthritis. [METHODS] We conducted three analyses: a lifetime analysis with a cohort model (Study A) and two short-term analyses (Studies B and C). Study A evaluated the incre... | Biological drugs; cost-effectiveness; rheumatoid arthritis | 0.727 | 71 | Medicine; Rheumatology | Medicine | 2,023 |
35,445,476 | Calculated parameters of luminal esophageal temperatures predict esophageal injury following conventional and high-power short-duration radiofrequency pulmonary vein isolation. | Journal of cardiovascular electrophysiology | J Cardiovasc Electrophysiol | 33 | 6 | 10.1111/jce.15509 | eng | 2,022 | 6 | null | 2,022 | 4 | 30 | [BACKGROUND] Luminal esophageal temperature (LET) monitoring is not associated with reduced esophageal injury following pulmonary vein isolation (PVI). [OBJECTIVE] Detailed analysis of (the temporal and spatial gradients of) LET measurements may better predict the risk for esophageal injury. [METHODS] Between January 2... | atrial fibrillation; esophageal injury; esophageal temperature monitoring; pulmonary vein isolation | 0.969 | 154 | Cardiology and Cardiovascular Medicine; Physiology | Medicine | 2,022 |
35,445,076 | Percutaneous Cannulated Screw Fixation vs. Plating With Minimally Invasive Longitudinal Approach After Closed Reduction for Intra-Articular Tongue-Type Calcaneal Fractures: A Retrospective Cohort Study. | Frontiers in surgery | Front Surg | 9 | null | 10.3389/fsurg.2022.854210 | eng | 2,022 | null | null | 2,022 | 4 | 4 | [OBJECTIVE] Displaced intra-articular tongue-type fractures are often treated with surgical interventions, and there is a lack of consensus regarding the surgical approach. This retrospective cohort study aimed to compare percutaneous cannulated screw (PCS) fixation and plating with a minimally invasive longitudinal ap... | calcaneus; closed reduction; joint depression type; minimally invasive longitudinal approach; percutaneous cannulated screw fixation; tongue-type fracture | 0.459 | 48 | Surgery | Medicine | 2,022 |
35,445,052 | Cardiovascular Protective Effects of Oral Hypoxia Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat in the Treatment of Type 4 Cardiorenal-Anemia Syndrome: Protocol of a Randomized Controlled Trial. | Frontiers in medicine | Front Med (Lausanne) | 9 | null | 10.3389/fmed.2022.783387 | eng | 2,022 | null | null | 2,022 | 4 | 4 | [BACKGROUND] Patients with chronic kidney disease (CKD) are at high risk of developing heart failure and anemia, which is defined as type 4 cardiorenal-anemia syndrome (CRAS). CRAS aggravates the deterioration of both kidney and heart function, ultimately resulting in a high mortality. This study aims to examine the ef... | anemia; cardiorenal-anemia syndrome; chronic kidney disease; heart failure; roxadustat | 0.926 | 102 | Medicine | Medicine | 2,022 |
35,445,034 | Correlation Between Clinical Factors and Pregnancy Outcome Following Repeat Cerclage: A Retrospective Analysis of a Chinese Population. | Frontiers in medicine | Front Med (Lausanne) | 9 | null | 10.3389/fmed.2022.846755 | eng | 2,022 | null | null | 2,022 | 4 | 4 | [BACKGROUND] The role of repeat cerclage (RC) among patients with prolapsed membranes remains controversial. We aimed to investigate the effectiveness of RC and assess the correlation between clinical factors and pregnancy outcome following RC. [METHODS] The clinical data of patients who underwent RC for prolapsed memb... | gestational age; pregnancy outcome; prolapsed membranes; repeat cerclage; retrospective analysis | 0.926 | 102 | Medicine | Medicine | 2,022 |
35,444,962 | Clinical Characteristics of Bloodstream Infection in Immunosuppressed Patients: A 5-Year Retrospective Cohort Study. | Frontiers in cellular and infection microbiology | Front Cell Infect Microbiol | 12 | null | 10.3389/fcimb.2022.796656 | eng | 2,022 | null | null | 2,022 | 4 | 4 | [INTRODUCTION] Immunosuppressed patients with bloodstream infection are at risk of mortality. Our objective was to assess the independent risk factors of bloodstream infection with mortality in immunosuppressive states. [METHODS] The medical data of a total of 896 patients who were hospitalized in our hospital were col... | bloodstream infection; different subgroups; immunosuppressive states; mortality; prognosis | 1.308 | 136 | Infectious Diseases; Medicine; Microbiology; Microbiology; Immunology | Immunology and Microbiology; Medicine | 2,022 |
35,444,825 | The Effect of E-Learning on Self-Efficacy and Sense of Coherence of Cancer Caregivers: Application of the Bandura and Antonovsky Social Cognitive Theory. | Current health sciences journal | Curr Health Sci J | 47 | 4 | 10.12865/CHSJ.47.04.09 | eng | 2,021 | null | null | 2,021 | 12 | 31 | [AIM] Cancer is one of the most important chronic diseases which affects caregivers. Therefore, in this study, we decided to increase the self-efficacy and sense of coherence of caregivers by using virtual learning via mobile to increase the power of managing in such situations. [METHODS] This study is a clinical trial... | Cancer; Caregiver; E-Learning; Self-efficacy; Sense of Coherence | null | null | null | null | null |
35,444,812 | Prevalence and comorbidity of psychiatric disorders among treatment-seeking elite athletes and high-performance coaches. | BMJ open sport exercise medicine | BMJ Open Sport Exerc Med | 8 | 1 | 10.1136/bmjsem-2021-001264 | eng | 2,022 | null | null | 2,022 | 3 | 29 | [OBJECTIVES] Few studies have evaluated the prevalence of psychiatric disorders among treatment-seeking elite athletes (EA) or high-performance coaches (HPC) in psychiatric outpatient settings. [METHODS] Descriptive overview of EA and HPC with psychiatric disorders at two publicly funded psychiatric outpatient treatmen... | anxiety; depression; eating disorders; psychiatry; stress | null | null | null | null | null |
35,444,403 | Endoscopic Bariatric Therapies: Current Status and Future Perspectives. | JSLS : Journal of the Society of Laparoendoscopic Surgeons | JSLS | 26 | 1 | 10.4293/JSLS.2021.00066 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Obesity is a chronic, multifactorial disease associated with multiple cardiometabolic conditions. The successful management of this condition includes a multidisciplinary approach with interventions focused on lifestyle modification, pharmaceutical therapies, and bariatric surgery. Endoscopic bariatric the... | Bariatric surgery; Diabetes; Endoscopic bariatric therapies; Endoscopy; Obesity | null | null | null | null | null |
35,444,387 | Mild Grisel Syndrome: Expanding the Differential for Posttonsillectomy Adenoidectomy Symptoms. | Federal practitioner : for the health care professionals of the VA, DoD, and PHS | Fed Pract | 39 | 2 | 10.12788/fp.0218 | eng | 2,022 | 2 | null | 2,022 | 2 | 18 | [BACKGROUND] Tonsillectomy with or without adenoidectomy is the second most common pediatric surgical procedure in the United States with up to 97% performed as an outpatient.1,2 While it is largely a safe procedure, several complications have been described and are encountered in the emergency department and primary c... | null | null | null | null | null | null |
35,444,033 | Anterior Cervical Discectomy and Fusion With a No-Profile Integrated Fixation Allograft Device: An In Vitro Biomechanical Analysis and Clinical Case Series. | International journal of spine surgery | Int J Spine Surg | 16 | 2 | 10.14444/8224 | eng | 2,022 | 4 | null | null | null | null | [BACKGROUND] No-profile anterior cervical discectomy and fusion (ACDF) devices are commonplace in spinal surgery. Contained within the intervertebral margins, these devices diminish risks associated with anterior cervical plating, while also marginalizing cage migration and subsidence. However, these devices have been ... | ACDF; allograft; biomechanics; cervical; degenerative; integrated; no-profile; zero-Profile | 0.591 | 40 | Orthopedics and Sports Medicine; Surgery | Medicine | 2,022 |
35,443,821 | Decreasing public interest in social psychiatry: An infodemiological study of worldwide Google search volumes from 2004 to 2021. | The International journal of social psychiatry | Int J Soc Psychiatry | 69 | 1 | 10.1177/00207640221090960 | eng | 2,023 | 2 | null | 2,022 | 4 | 20 | [BACKGROUND] While mental disorder is an 'intrinsically social phenomenon', social psychiatry has been reportedly declining. Addressing public interests in social psychiatry was among the suggestions to address this decline. In recent years, public interest in social psychiatry can be explored using Google Trends, an i... | Google; Trends; decline; global; psychiatry; social | 1.649 | 86 | Medicine; Psychiatry and Mental Health | Medicine | 2,023 |
35,443,514 | Association of injection Tocilizumab and inflammatory markers in COVID19. | The Journal of the Association of Physicians of India | J Assoc Physicians India | 70 | 4 | null | eng | 2,022 | 4 | null | null | null | null | [UNLABELLED] The coronavirus disease 2019 (COVID-19) virus has spread all over the world. Scientists are trying to discover drugs as effective treatment for patients with COVID-19. So far about 30 drugs have been introduced that one of them is Tocilizumab. Some reports showed a positive effect of Tocilizumab on Saturat... | null | null | null | null | null | null |
35,443,495 | A Study of Procalcitonin as an Early Predictor of Severity in Acute Pancreatitis. | The Journal of the Association of Physicians of India | J Assoc Physicians India | 70 | 4 | null | eng | 2,022 | 4 | null | null | null | null | [UNLABELLED] Acute Pancreatitis is an acute inflammation of the pancreas.Acute pancreatitis is an acute inflammatory process ranging clinically from mild discomfort with localized inflammation to severe disease involving remote organ systems. There is a continuum from the development of systemic inflammatory response s... | null | null | null | null | null | null |
35,443,487 | Prognostic Role of Ngal in Critically Ill Patients. | The Journal of the Association of Physicians of India | J Assoc Physicians India | 70 | 4 | null | eng | 2,022 | 4 | null | null | null | null | [UNLABELLED] Acute kidney injury (AKI) is a frequently encountered outcome in critically ill patients, accounting for increased mortality. Neutrophil gelatinase associated lipocalin (NGAL) has been of paramount importance as a novel biomarker of AKI. This study is an attempt to assess the use of NGAL in critically ill ... | null | null | null | null | null | null |
35,443,423 | Clinical Profile of Central Nervous System Involvement in Patients with Rhino Orbital Cerebral Mucormycosis. | The Journal of the Association of Physicians of India | J Assoc Physicians India | 70 | 4 | null | eng | 2,022 | 4 | null | null | null | null | [UNLABELLED] Mucormycosis is life threatening fungal infection that occurs in immunocompromised patients. Patients at risk are those with poorly controlled diabetes mellitus, immunosuppressed patients such as those undergoing treatment for hematological cancer or recipients of solid organ and hematopoietic stem cell tr... | null | null | null | null | null | null |
35,443,359 | Correlation of Spo2 Measurement by Pulseoximetry with Arterial Blood Gas Analysis in Patients with Uncontrolled Type 2 Diabetes On Oxygen Therapy. | The Journal of the Association of Physicians of India | J Assoc Physicians India | 70 | 4 | null | eng | 2,022 | 4 | null | null | null | null | [UNLABELLED] Pulse oximetry is widely used as a noninvasive tool for continuous monitoring of artery oxygen saturation (SaO2) but pulse oximeter oxygen saturation (SpO2) may overestimate arterial blood gases-determined SaO2 in acute sickle chest syndrome and severe sepsis. [OBJECTIVES] To estimate difference in Spo2 le... | null | null | null | null | null | null |
35,442,971 | Increased functional connectivity between limbic brain areas in healthy individuals with high versus low sensitivity to cold pain: A resting state fMRI study. | PloS one | PLoS One | 17 | 4 | 10.1371/journal.pone.0267170 | eng | 2,022 | null | null | 2,022 | 4 | 20 | [BACKGROUND] The representation of variability in sensitivity to pain by differences in neural connectivity patterns and its association with psychological factors needs further investigation. This study assessed differences in resting-state functional connectivity (rsFC) and its association to cognitive-affective aspe... | null | 0.885 | 467 | Multidisciplinary | Multidisciplinary | 2,022 |
35,442,583 | Pilot Study of Feeding Tube Education Using a Graphic-Based Course. | WMJ : official publication of the State Medical Society of Wisconsin | WMJ | 121 | 1 | null | eng | 2,022 | 4 | null | null | null | null | [BACKGROUND] Residents receive little formal education about feeding tubes; however, patients experience fewer complications if a formal feeding tube curriculum is implemented. [OBJECTIVE] The aim of this study was to evaluate a graphics-based course for internal medicine residents. [METHODS] Internal medicine resident... | null | null | null | null | null | null |
35,442,580 | Pediatric Respiratory Illness Hospitalizations Prior to COVID-19 and During the First Year of the COVID-19 Pandemic in Southeast Wisconsin. | WMJ : official publication of the State Medical Society of Wisconsin | WMJ | 121 | 1 | null | eng | 2,022 | 4 | null | null | null | null | [BACKGROUND] Public health measures combatting the COVID-19 pandemic also led to a decrease in other pediatric respiratory illnesses. We describe the local pattern of pediatric respiratory hospitalizations in southeast Wisconsin prior to COVID-19 and during the first year of the pandemic. [METHODS] We performed a cross... | null | null | null | null | null | null |
35,442,450 | Association of Playing College American Football With Long-term Health Outcomes and Mortality. | JAMA network open | JAMA Netw Open | 5 | 4 | 10.1001/jamanetworkopen.2022.8775 | eng | 2,022 | 4 | 1 | 2,022 | 4 | 1 | [IMPORTANCE] Exposure to repetitive head impacts from playing American football (including impacts resulting in symptomatic concussions and subconcussive trauma) is associated with increased risk for later-life health problems, including cognitive and neuropsychiatric decline and neurodegenerative disease. Most researc... | null | 4.108 | 154 | Medicine | Medicine | 2,022 |
35,442,432 | Effect of Culturally Tailored, Internet-Delivered Cognitive Behavioral Therapy for Insomnia in Black Women: A Randomized Clinical Trial. | JAMA psychiatry | JAMA Psychiatry | 79 | 6 | 10.1001/jamapsychiatry.2022.0653 | eng | 2,022 | 6 | 1 | null | null | null | [IMPORTANCE] Black women are at risk for insomnia disorder. Despite interest in addressing sleep health disparities, there is limited research investigating the efficacy of criterion-standard treatment (cognitive behavioral therapy for insomnia [CBT-I]) among this racial minority population. [OBJECTIVE] To compare the ... | null | null | null | null | null | null |
35,442,391 | Prevalence, Comorbidity, and Sociodemographic Correlates of Psychiatric Disorders Reported in the All of Us Research Program. | JAMA psychiatry | JAMA Psychiatry | 79 | 6 | 10.1001/jamapsychiatry.2022.0685 | eng | 2,022 | 6 | 1 | null | null | null | [IMPORTANCE] All of Us is a landmark initiative for population-scale research into a variety of health conditions, including psychiatric disorders. [OBJECTIVE] To analyze the prevalence, comorbidity, and sociodemographic covariates of psychiatric disorders in the All of Us biobank. [DESIGN, SETTING, AND PARTICIPANTS] W... | null | null | null | null | null | null |
35,442,361 | Prevalence of molecular and serological tests of the new coronavirus (SARS-CoV-2) in Carlos Chagas laboratory - Sabin group in Cuiabá. | Revista da Associacao Medica Brasileira (1992) | Rev Assoc Med Bras (1992) | 68 | 3 | 10.1590/1806-9282.20210769 | eng | 2,022 | 3 | null | null | null | null | [BACKGROUND] Coronavirus disease 2019, which is caused by the new severe acute respiratory syndrome coronavirus 2, became a pandemic in 2020 with a mortality rate of 2% and high transmissibility, thus making studies with an epidemiological profile essential. [OBJECTIVES] The aim of this study was to characterize the po... | null | 0.318 | 51 | Medicine | Medicine | 2,022 |
35,442,193 | The Clinical Variant Analysis Tool: Analyzing the evidence supporting reported genomic variation in clinical practice. | Genetics in medicine : official journal of the American College of Medical Genetics | Genet Med | 24 | 7 | 10.1016/j.gim.2022.03.013 | eng | 2,022 | 7 | null | 2,022 | 4 | 19 | [PURPOSE] Genomic test results, regardless of laboratory variant classification, require clinical practitioners to judge the applicability of a variant for medical decisions. Teaching and standardizing clinical interpretation of genomic variation calls for a methodology or tool. [METHODS] To generate such a tool, we di... | Exome sequencing; Genomic medicine; Precision medicine; Variant classification; Variant interpretation | 2.745 | 167 | Genetics; Medicine | Medicine | 2,022 |
35,442,093 | Comparative study of conventional diffusion-weighted imaging and introvoxel incoherent motion in assessment of pathological grade of clear cell renal cell carcinoma. | The British journal of radiology | Br J Radiol | 95 | 1133 | 10.1259/bjr.20210485 | eng | 2,022 | 5 | 1 | 2,022 | 2 | 9 | [OBJECTIVE] To quantitatively compare the diagnostic values of conventional diffusion-weighted imaging (DWI) and introvoxel incoherent motion (IVIM) analysis of microstructural differences for clear cell renal cell carcinoma (ccRCC). [METHODS] Multiple b value DWIs and IVIMs were performed in patients with 146 ccRCCs, ... | null | 0.757 | 128 | Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,022 |
35,441,889 | Adult brainstem glioma differential diagnoses: an MRI-based approach in a series of 68 patients. | Journal of neurology | J Neurol | 269 | 8 | 10.1007/s00415-022-11070-6 | eng | 2,022 | 8 | null | 2,022 | 4 | 20 | [BACKGROUND] Brainstem gliomas are rare in adults. The diagnosis is often difficult, as some teams still consider brainstem biopsies dangerous and often avoid this procedure. The aim of this study was to describe differential diagnoses that can mimic brainstem glioma, to help clinicians avoid diagnostic and therapeutic... | Brainstem; Differential diagnoses; Gliomas; Magnetic resonance imaging | 1.556 | 168 | Neurology; Neurology | Medicine; Neuroscience | 2,022 |
35,441,470 | Weight regain and cardiometabolic effects after withdrawal of semaglutide: The STEP 1 trial extension. | Diabetes, obesity metabolism | Diabetes Obes Metab | 24 | 8 | 10.1111/dom.14725 | eng | 2,022 | 8 | null | 2,022 | 5 | 19 | [AIM] To explore changes in body weight and cardiometabolic risk factors after treatment withdrawal in the STEP 1 trial extension. [MATERIALS AND METHODS] STEP 1 (NCT03548935) randomized 1961 adults with a body mass index ≥ 30 kg/m[2] (or ≥ 27 kg/m[2] with ≥ 1 weight-related co-morbidity) without diabetes to 68 weeks o... | GLP-1 analogue; antiobesity drug; clinical trial; obesity therapy; phase III study; weight control | null | null | null | null | null |
35,441,433 | Home monitoring of lung function, symptoms and quality of life after admission with COVID-19 infection: The HOMECOMIN' study. | Respirology (Carlton, Vic.) | Respirology | 27 | 7 | 10.1111/resp.14262 | eng | 2,022 | 7 | null | 2,022 | 4 | 19 | [BACKGROUND AND OBJECTIVE] To develop targeted and efficient follow-up programmes for patients hospitalized with coronavirus disease 2019 (COVID-19), structured and detailed insights in recovery trajectory are required. We aimed to gain detailed insights in long-term recovery after COVID-19 infection, using an online h... | COVID-19; chronic lung disease; coronavirus disease; eHealth; health-related quality of life; home spirometry; patient-reported outcome measures; telemedicine | 1.294 | 113 | Pulmonary and Respiratory Medicine | Medicine | 2,022 |
35,441,345 | Outcome and prognostic factors in patients undergoing salvage therapy for recurrent esophagogastric cancer after multimodal treatment. | Journal of cancer research and clinical oncology | J Cancer Res Clin Oncol | 149 | 4 | 10.1007/s00432-022-04016-y | eng | 2,023 | 4 | null | 2,022 | 4 | 19 | [PURPOSE] Perioperative systemic treatment has significantly improved the outcome in locally advanced esophagogastric cancer. However, still the majority of patients relapse and die. Data on the optimal treatment after relapse are limited, and clinical and biological prognostic factors are lacking. [METHODS] Patients w... | Esophagogastric cancer; MSI; Perioperative treatment; Relapse; Salvage treatment | 1.023 | 114 | Medicine; Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,023 |
35,441,331 | Assessment of Textbook Oncologic Outcomes Following Proctectomy for Rectal Cancer. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract | J Gastrointest Surg | 26 | 6 | 10.1007/s11605-021-05213-9 | eng | 2,022 | 6 | null | 2,022 | 4 | 19 | [BACKGROUND] Outcomes of rectal adenocarcinoma vary considerably. Composite "textbook oncologic outcome" (TOO) is a single metric that estimates optimal clinical performance for cancer surgery. [METHODS] Patients with stage II/III rectal adenocarcinoma who underwent single-agent neoadjuvant chemoradiation and proctecto... | Rectal adenocarcinoma; Textbook outcomes | 0.97 | 149 | Surgery; Gastroenterology | Medicine | 2,022 |
35,441,198 | Social Participation's Association with Falls and Frailty in Malaysia: A Cross-Sectional Study. | The Journal of frailty aging | J Frailty Aging | 11 | 2 | 10.14283/jfa.2021.31 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] The global population is ageing rapidly, with the most dramatic increases in developing countries like Malaysia. Older people are at increased risk of multimorbidity, frailty and falls. [OBJECTIVES] In this study we aimed to determine the relationship between social participation, frailty and falls in Mala... | Healthy ageing; community; falls; frailty; social isolation | null | null | null | null | null |
35,441,069 | Acellular Dermal Matrices in Breast Reconstruction: CARE Trial 5-Year Outcomes Data for More Than 9500 Patients. | Plastic and reconstructive surgery. Global open | Plast Reconstr Surg Glob Open | 10 | 4 | 10.1097/GOX.0000000000004258 | eng | 2,022 | 4 | null | 2,022 | 4 | 14 | [UNLABELLED] Few studies have assessed long-term complications in women undergoing implant-based breast reconstruction with use of an acellular dermal matrix (ADM). This study compared outcomes over 5 years in women undergoing breast reconstruction procedures with and without ADM. [METHODS] Complications data in patien... | null | 0.671 | 57 | Surgery | Medicine | 2,022 |
35,441,067 | Final 24-hour Drain Output and Postoperative Day Are Poor Indicators for Appropriate Drain Removal. | Plastic and reconstructive surgery. Global open | Plast Reconstr Surg Glob Open | 10 | 4 | 10.1097/GOX.0000000000004160 | eng | 2,022 | 4 | null | 2,022 | 4 | 14 | [UNLABELLED] Drains are used in plastic surgery to remove excess fluid while ameliorating complications. However, there is a paucity of evidence supporting guiding parameters on when to discontinue a drain. The aim of our study was to determine whether two of the most common parameters, drain volume 24 hours before rem... | null | 0.671 | 57 | Surgery | Medicine | 2,022 |
35,440,451 | Is carotid artery atherosclerosis associated with poor cognitive function assessed using the Mini-Mental State Examination? A systematic review and meta-analysis. | BMJ open | BMJ Open | 12 | 4 | 10.1136/bmjopen-2021-055131 | eng | 2,022 | 4 | 19 | 2,022 | 4 | 19 | [OBJECTIVES] To determine associations between carotid atherosclerosis assessed by ultrasound and the Mini-Mental State Examination (MMSE), a measure of global cognitive function. [DESIGN] Systematic review and meta-analysis. [METHODS] MEDLINE and EMBASE databases were searched up to 1 May 2020 to identify studies asse... | Cardiovascular imaging; Dementia; Ultrasound; VASCULAR MEDICINE | 1.059 | 176 | Medicine | Medicine | 2,022 |
35,440,378 | Graft repair of arteriovenous fistula aneurysms is associated with decreased long-term patency. | American journal of surgery | Am J Surg | 224 | 1 Pt A | 10.1016/j.amjsurg.2022.04.009 | eng | 2,022 | 7 | null | 2,022 | 4 | 15 | [INTRODUCTION] Arteriovenous fistula (AVF) aneurysms are a chronic complication which can be disfiguring, painful, and can rupture. Here, we compare the outcomes between three different methods of AVF aneurysm repair. [METHODS] One-way ANOVA, Chi-square, and Fisher Exact analyses were used to compare demographics. Mult... | null | 0.85 | 173 | Surgery; Medicine | Medicine | 2,022 |
35,439,928 | The effect of subdiaphragmatic vagotomy on heart rate variability and lung inflammation in rats with severe hemorrhagic shock. | BMC cardiovascular disorders | BMC Cardiovasc Disord | 22 | 1 | 10.1186/s12872-022-02594-w | eng | 2,022 | 4 | 19 | 2,022 | 4 | 19 | [BACKGROUND] The influence of cutting the sub-diaphragmatic branch of the vagus nerve on heart rate variability (HRV) and inflammatory reaction to severe hemorrhagic shock has not been determined prior to this study. [METHODS] Male Sprague-Dawley rats were divided into four groups of Sham, sub-diaphragmatic vagotomized... | HRV; Shock; Vagus nerve; iNOS | 0.601 | 76 | Cardiology and Cardiovascular Medicine | Medicine | 2,022 |
35,439,881 | A clinical and radiographic comparative evaluation of custom-made zirconia crowns using CAD-CAM and stainless steel crowns in primary molars. | Journal of the Indian Society of Pedodontics and Preventive Dentistry | J Indian Soc Pedod Prev Dent | 40 | 1 | 10.4103/jisppd.jisppd_269_21 | eng | 2,022 | null | null | null | null | null | [BACKGROUND AND AIM OF STUDY] Early childhood caries is a multifactorial disease process affecting children below 71 months of age and continues to be a global health problem. Stainless steel crowns (SSCs) are widely used and are very popular in pediatric dentistry due to its superiority and durability when compared wi... | clinical evaluation; parental satisfaction; preformed stainless steel crowns; radiographic evaluation | null | null | null | null | null |
35,439,758 | A Composite of Hepatocyte Growth Factor- and 5α-Dihydrotestosterone-Gelatin Microspheres with Adipose-Derived Stem Cells Enhances Wound Healing. | Skin pharmacology and physiology | Skin Pharmacol Physiol | 35 | 4 | 10.1159/000524188 | eng | 2,022 | null | null | 2,022 | 4 | 19 | [INTRODUCTION] Reconstructing sebaceous glands is one goal of functionally healing patients who have suffered severe burns, instead of the simple pursuit of wound closure. Effective regeneration of skin appendages remains a challenge in skin wound management and research. [OBJECTIVE] The aim of this study was to evalua... | Adipose-derived stem cells; Gelatin microspheres; Hepatocyte growth factor; Sebaceous glands; Wound healing | 0.534 | 89 | Dermatology; Medicine; Pharmacology; Physiology | Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,022 |
35,439,757 | Small RNA Sequencing Reveals Exosomal miRNAs as Unique Feature Markers in Unprovoked Venous Thromboembolism. | Acta haematologica | Acta Haematol | 145 | 5 | 10.1159/000524569 | eng | 2,022 | null | null | 2,022 | 4 | 19 | [INTRODUCTION] Venous thromboembolism (VTE) is a common cardiovascular disease. MicroRNAs (miRNAs) play a key role in VTE; however, the role of exosomal miRNAs in VTE remains unknown. Therefore, we aimed to identify key exosomal miRNAs and their potential mechanisms in VTE. [METHODS] We collected 31 samples from unprov... | Biomarker; Exosomal microRNA sequencing; MicroRNA-messenger RNA network; Venous thromboembolism; qPCR | 0.719 | 65 | Hematology; Medicine | Medicine | 2,022 |
35,439,632 | Development and psychometric testing of learning immersion scale in clinical simulation: A methodological study. | Nurse education today | Nurse Educ Today | 113 | null | 10.1016/j.nedt.2022.105363 | eng | 2,022 | 6 | null | 2,022 | 4 | 10 | [BACKGROUND] Immersion during clinical simulation has been suggested to be important for learning effects. However, no valid and reliable instruments have been available for measuring the learner's immersion during simulation experience. [OBJECTIVES] To develop a Learning Immersion Scale in Simulation (LISS) and evalua... | Immersion; Instrument; Reliability; Scale; Simulation training; Validity | 0.946 | 109 | Education; Nursing | Nursing; Social Sciences | 2,022 |
35,439,246 | Evaluation of an online intervention for improving stroke survivors' health-related quality of life: A randomised controlled trial. | PLoS medicine | PLoS Med | 19 | 4 | 10.1371/journal.pmed.1003966 | eng | 2,022 | 4 | null | 2,022 | 4 | 19 | [BACKGROUND] The aim of this trial was to evaluate the effectiveness of an online health behaviour change intervention-Prevent 2nd Stroke (P2S)-at improving health-related quality of life (HRQoL) amongst stroke survivors at 6 months of follow-up. [METHODS AND FINDINGS] A prospective, blinded-endpoint randomised control... | null | 4.223 | 289 | Biochemistry; Biotechnology; Cell Biology; Medicine; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,438,777 | US Severe Acute Respiratory Syndrome Coronavirus 2 Epsilon Variant: Highly Transmissible but With an Adjusted Muted Host T-Cell Response. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | Clin Infect Dis | 75 | 11 | 10.1093/cid/ciac295 | eng | 2,022 | 11 | 30 | null | null | null | [BACKGROUND] The multiple mutations comprising the epsilon variant demonstrate the independent convergent evolution of severe acute respiratory syndrome coronavirus (SARS-CoV-2), with its spike protein mutation L452R present in the delta (L452R), kappa (L452R), and lambda (L452Q) variants. [METHODS] Coronavirus disease... | COVID; T-cell response; proteomics; transcriptomics; variant | 3.995 | 398 | Infectious Diseases; Microbiology | Medicine | 2,022 |
35,438,765 | β-Lactam-Resistant Streptococcus pneumoniae Dynamics Following Treatment: A Dose-Response Meta-analysis. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | Clin Infect Dis | 75 | 11 | 10.1093/cid/ciac293 | eng | 2,022 | 11 | 30 | null | null | null | [BACKGROUND] Patient exposure to antibiotics promotes the emergence of drug-resistant pathogens. The aim of this study was to identify whether the temporal dynamics of resistance emergence at the individual-patient level were predictable for specific pathogen-drug classes. [METHODS] Following a systematic review, a nov... | antibiotics; drug resistance; penicillin | 3.995 | 398 | Infectious Diseases; Microbiology | Medicine | 2,022 |
35,438,638 | Adapting the Use of Digital Content to Improve the Learning of Numeracy Among Children With Autism Spectrum Disorder in Rwanda: Thematic Content Analysis Study. | JMIR serious games | JMIR Serious Games | 10 | 2 | 10.2196/28276 | eng | 2,022 | 4 | 19 | 2,022 | 4 | 19 | [BACKGROUND] Many teachers consider it challenging to teach children with autism spectrum disorder (ASD) in an inclusive classroom due to their unique needs and challenges. The integration of information communication technology (ICT) in the education system allows children with ASD to improve their learning. However, ... | ASD; ICT; Rwanda; autism; behavior; children; communication; communication technology; e-learning; education; gamification; learning; online content; school; school-age children; teachers; teaching | 0.78 | 45 | Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Biomedical Engineering; Psychiatry and Mental Health | Engineering; Health Professions; Medicine | 2,022 |
35,438,210 | The effect of treatment delay on quality of life and overall survival in head and neck cancer patients. | European journal of cancer care | Eur J Cancer Care (Engl) | 31 | 4 | 10.1111/ecc.13589 | eng | 2,022 | 7 | null | 2,022 | 4 | 19 | [OBJECTIVE] Head and neck squamous cell carcinomas (HNSCC) are rapidly developing tumours, and substantial delay in treatment initiation is associated with decreased overall survival. The effect of delay on health-related quality of life (HRQOL) is unknown. The aim of this study was to assess the impact of delay on QOL... | head and neck neoplasms; overall survival; quality of life; time-to-treatment; treatment delay | 0.694 | 84 | Oncology | Medicine | 2,022 |
35,438,031 | Accuracy of digital templating in uncemented primary total hip arthroplasty: which factors are associated with accuracy of preoperative planning? | Hip international : the journal of clinical and experimental research on hip pathology and therapy | Hip Int | 33 | 3 | 10.1177/11207000221082026 | eng | 2,023 | 5 | null | 2,022 | 4 | 19 | [BACKGROUND] Preoperative planning is a fundamental step for successful total hip arthroplasty (THA). Studies have highlighted the accuracy of preoperative digital templating for estimating acetabular cup and stem size. Stem design such as single-wedge metadiaphyseal (Type 1 stem) versus mid-short stem (microplasty) an... | Accuracy; THA; digital templating; preoperative planning; stem design; surgical approach | 0.8 | 50 | Surgery; Orthopedics and Sports Medicine | Medicine | 2,023 |
35,438,028 | Revision Hip Arthroscopy With Labral Reconstruction for Irreparable Labral Tears in Athletes: Minimum 2-Year Outcomes With a Benchmark Control Group. | The American journal of sports medicine | Am J Sports Med | 50 | 6 | 10.1177/03635465221085030 | eng | 2,022 | 5 | null | 2,022 | 4 | 19 | [BACKGROUND] The incidence of revision hip arthroscopy with labral reconstruction in athletes is increasing. However, the outcomes of revision hip arthroscopy with labral reconstruction in athletes have not been well established. [PURPOSES] (1) To report minimum 2-year patient-reported outcome (PRO) scores and return t... | femoroacetabular impingement; labral reconstruction; return to sports | 2.477 | 277 | Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science | Health Professions; Medicine | 2,022 |
35,437,252 | Prevalence and predictors of influenza vaccination in long-term care homes: a cross-national retrospective observational study. | BMJ open | BMJ Open | 12 | 4 | 10.1136/bmjopen-2021-057517 | eng | 2,022 | 4 | 18 | 2,022 | 4 | 18 | [OBJECTIVE] To compare facility-level influenza vaccination rates in long-term care (LTC) homes from four countries and to identify factors associated with influenza vaccination among residents. [DESIGN AND SETTING] Retrospective cross-sectional study of individuals residing in LTC homes in New Brunswick (Canada), New ... | epidemiology; geriatric medicine; immunology; infection control; public health | 1.059 | 176 | Medicine | Medicine | 2,022 |
35,437,207 | An epidermal keratinocyte homogenate induced type 2 and proinflammatory cytokine expression in cultured dermal cells. | Journal of dermatological science | J Dermatol Sci | 106 | 2 | 10.1016/j.jdermsci.2022.04.002 | eng | 2,022 | 5 | null | 2,022 | 4 | 7 | [BACKGROUND] The "itch-scratch cycle" is a clinically well-known cause of exacerbation of atopic dermatitis (AD), but the underlying molecular mechanisms remain largely unknown. [OBJECTIVE] To test our hypothesis that some molecules released from damaged epidermal keratinocytes by scratching inducetype 2 responses in i... | null | 1.118 | 115 | Biochemistry; Dermatology; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,437,022 | Magnetic resonance imaging as a first-choice imaging modality in carpal tunnel syndrome: new evidence. | Acta radiologica (Stockholm, Sweden : 1987) | Acta Radiol | 64 | 2 | 10.1177/02841851221094227 | eng | 2,023 | 2 | null | 2,022 | 4 | 18 | [BACKGROUND] Carpal tunnel syndrome (CTS) is the most common type of peripheral nerve compression. Magnetic resonance imaging (MRI) is becoming more popular in practice in the evaluation of CTS. [PURPOSE] To evaluate the diagnostic value of MRI in CTS. [MATERIAL AND METHODS] A cross-sectional study of 39 wrists was con... | Boston Carpal Tunnel Questionnaire; Carpal tunnel syndrome; electrophysiology; magnetic resonance imaging | 0.429 | 82 | Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging | Health Professions; Medicine | 2,023 |
35,436,969 | Associations of the baseline level and change in glycosylated hemoglobin A1c with incident hypertension in non-diabetic individuals: a 3-year cohort study. | Diabetology metabolic syndrome | Diabetol Metab Syndr | 14 | 1 | 10.1186/s13098-022-00827-8 | eng | 2,022 | 4 | 18 | 2,022 | 4 | 18 | [BACKGROUND] Diabetes mellitus increases the risk of developing hypertension. The relationship between glycosylated hemoglobin A1c (HbA1c) level and incident hypertension remains controversial. This study examined the associations of the baseline level and change in the HbA1c level over 3 years with incident hypertensi... | Blood pressure; Cohort; Glycosylated hemoglobin A1c; Hypertension | null | null | null | null | null |
35,436,903 | Epidemiology and associated injuries in paediatric diaphyseal femur fractures treated at a limited resource zonal referral hospital in northern Tanzania. | BMC musculoskeletal disorders | BMC Musculoskelet Disord | 23 | 1 | 10.1186/s12891-022-05320-x | eng | 2,022 | 4 | 18 | 2,022 | 4 | 18 | [BACKGROUND] Diaphyseal femur fractures contribute up to 40% of paediatric orthopaedic admissions with the World Health Organisation data showing youth are particularly vulnerable and road traffic injuries are the leading cause of death for children and young adults. Different mechanisms results to these injuries and t... | Childhood; Femur; Fracture; Orthopaedic Injuries | 0.716 | 131 | Orthopedics and Sports Medicine; Rheumatology | Medicine | 2,022 |
35,436,868 | Resolution of severe eosinophilic peritonitis in a patient on continuous ambulatory peritoneal dialysis by changing from Dianeal peritoneal dialysis solution to Stay-Safe Balance solution: a case report. | BMC nephrology | BMC Nephrol | 23 | 1 | 10.1186/s12882-022-02786-8 | eng | 2,022 | 4 | 18 | 2,022 | 4 | 18 | [BACKGROUND] Eosinophilic peritonitis is a well-known complication at the initiation of peritoneal dialysis. It is often due to an allergic reaction to peritoneal dialysis solution or sometimes to the peritoneal dialysis catheter itself. Most cases are self-limiting with expected spontaneous resolution within a few wee... | Peritoneal dialysis; allergic reaction; case report; eosinophilic peritonitis; treatment | 0.746 | 83 | Nephrology | Medicine | 2,022 |
35,436,572 | Image postproduction analysis as a tool for evaluating topical photodynamic therapy in the treatment of oral lichen planus. | Photodiagnosis and photodynamic therapy | Photodiagnosis Photodyn Ther | 39 | null | 10.1016/j.pdpdt.2022.102868 | eng | 2,022 | 9 | null | 2,022 | 4 | 15 | [BACKGROUND] Topical Photodynamic Therapy (PDT) is a minimally invasive technique used in various medical specialties. The method involves the use of a light source and a photosensitizer leading to the release of Reactive Oxygen Species and a cytotoxic effect on lesional tissue. PDT can treat various lesions , and in p... | Lichen planus; OLP; OPMD; Photodynamic therapy; Postproduction analysis; ROS; Reactive oxygen species | 0.633 | 73 | Biophysics; Dermatology; Pharmacology; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,436,524 | Representativeness of trial participants: linking the EORTC boost-no boost trial to the Netherlands cancer registry. | Journal of clinical epidemiology | J Clin Epidemiol | 148 | null | 10.1016/j.jclinepi.2022.04.014 | eng | 2,022 | 8 | null | 2,022 | 4 | 15 | [BACKGROUND AND OBJECTIVES] To evaluate the representativeness of Dutch patients participating in the European Organization for Research and Treatment of Cancer EORTC boost-no-boost trial to the target breast cancer patient population. [METHODS] All female breast cancer patients diagnosed between 1989 and 1996, aged ≤7... | Boost radiation therapy; Breast cancer; Data linkage; Registry; Representativeness; Trial | 3.362 | 262 | Epidemiology | Medicine | 2,022 |
35,436,498 | Deep Submucosal Invasion Is Not an Independent Risk Factor for Lymph Node Metastasis in T1 Colorectal Cancer: A Meta-Analysis. | Gastroenterology | Gastroenterology | 163 | 1 | 10.1053/j.gastro.2022.04.010 | eng | 2,022 | 7 | null | 2,022 | 4 | 15 | [BACKGROUND AND AIMS] Deep submucosal invasion (DSI) is considered a key risk factor for lymph node metastasis (LNM) and important criterion to recommend surgery in T1 colorectal cancer. However, metastatic risk for DSI is shown to be low in the absence of other histologic risk factors. This meta-analysis determines th... | Deep Submucosal Invasion; Lymph Node Metastasis; Risk Stratification; T1 Colorectal Cancer | 7.645 | 482 | Gastroenterology; Hepatology | Medicine | 2,022 |
35,435,870 | Multisystem Inflammatory Syndrome in Children and Acute Kidney Injury: Retrospective Study of Five Italian PICUs. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies | Pediatr Crit Care Med | 23 | 7 | 10.1097/PCC.0000000000002955 | eng | 2,022 | 7 | 1 | 2,022 | 4 | 18 | [OBJECTIVES] Multisystem inflammatory syndrome in children (MIS-C) manifests with heart dysfunction and respiratory failure some weeks after a severe acute respiratory syndrome coronavirus disease 2 infection. The aim of our study was to explore the prevalence, severity, timing, and duration of acute kidney injury (AKI... | null | 1.42 | 111 | Critical Care and Intensive Care Medicine; Pediatrics, Perinatology and Child Health | Medicine | 2,022 |
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