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35,473,609 | Tryptophan hydroxylase 1 drives glioma progression by modulating the serotonin/L1CAM/NF-κB signaling pathway. | BMC cancer | BMC Cancer | 22 | 1 | 10.1186/s12885-022-09569-2 | eng | 2,022 | 4 | 26 | 2,022 | 4 | 26 | [BACKGROUND] Glioma is one of the main causes of cancer-related mortality worldwide and is associated with high heterogeneity. However, the key players determining the fate of glioma remain obscure. In the present study, we shed light on tumor metabolism and aimed to investigate the role of tryptophan hydroxylase 1 (TP... | Glioma; L1CAM; Serotonin; TPH-1 | 1.137 | 171 | Genetics; Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,473,366 | The Natural History of Initial Antipsychotic Treatment Among Men Admitted to a State Prison. | Psychiatric services (Washington, D.C.) | Psychiatr Serv | 73 | 10 | 10.1176/appi.ps.202100545 | eng | 2,022 | 10 | 1 | 2,022 | 4 | 27 | [OBJECTIVE] This study examined the natural history of antipsychotic medication treatment for men with a psychotic disorder who entered the North Carolina prison system in 2016-2017. [METHODS] The authors used prison records to identify individuals with a psychotic illness who were prescribed an index antipsychotic med... | Adherence; Antipsychotics; Mental health services; Prisons; Psychoses; Schizophrenia | 1.405 | 174 | Medicine; Psychiatry and Mental Health | Medicine | 2,022 |
35,473,346 | Specific acupuncture stimulation of Shenshu (BL23) affects sympathetic nervous activity-associated plasma renin concentration changes. | Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan | J Tradit Chin Med | 42 | 2 | 10.19852/j.cnki.jtcm.2022.02.005 | eng | 2,022 | 4 | null | null | null | null | [OBJECTIVE] To examine whether specific stimulation of Shenshu (BL23) affects sympathetic nervous activity (SNA)-associated plasma renin concentration (PRC). [METHODS] Eight healthy volunteers participated in three pattern conditions in random order: control (Cont), stimulation of Shenshu (BL23), and stimulation of sha... | Acupuncture; Plasma renin concentration; Point BL23 (Shenshu); Sympathetic nervous activity | null | null | null | null | null |
35,472,243 | Safety and Activity of PolyPEPI1018 Combined with Maintenance Therapy in Metastatic Colorectal Cancer: an Open-Label, Multicenter, Phase Ib Study. | Clinical cancer research : an official journal of the American Association for Cancer Research | Clin Cancer Res | 28 | 13 | 10.1158/1078-0432.CCR-22-0112 | eng | 2,022 | 7 | 1 | null | null | null | [PURPOSE] Although chemotherapy is standard of care for metastatic colorectal cancer (mCRC), immunotherapy has no role in microsatellite stable (MSS) mCRC, a "cold" tumor. PolyPEPI1018 is an off-the-shelf, multi-peptide vaccine derived from 7 tumor-associated antigens (TAA) frequently expressed in mCRC. This study asse... | null | 4.603 | 392 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,472,089 | Evolution of Proximal Junctional Kyphosis and Proximal Junctional Failure Rates Over 10 Years of Enrollment in a Prospective Multicenter Adult Spinal Deformity Database. | Spine | Spine (Phila Pa 1976) | 47 | 13 | 10.1097/BRS.0000000000004364 | eng | 2,022 | 7 | 1 | 2,022 | 4 | 21 | [STUDY DESIGN] Retrospective cohort study. [OBJECTIVE] The aim of this study was to investigate the evolution of proximal junctional kyphosis (PJK) rate over 10-year enrollment period within a prospective database. [SUMMARY OF BACKGROUND DATA] PJK is a common complication following adult spinal deformity (ASD) surgery ... | null | 1.197 | 300 | Neurology; Orthopedics and Sports Medicine; Sports Science | Health Professions; Medicine | 2,022 |
35,472,013 | Antibiotic prescribing patterns and guideline-concordant management of acute respiratory tract infections in virtual urgent care settings. | Journal of the American Association of Nurse Practitioners | J Am Assoc Nurse Pract | 34 | 6 | 10.1097/JXX.0000000000000705 | eng | 2,022 | 6 | 1 | 2,022 | 6 | 1 | [BACKGROUND] Antibiotic overprescribing for acute respiratory tract infections (ARTIs) commonly occurs and can lead to higher medical costs, antibiotic resistance, and health complications. Inappropriate prescribing of antibiotics for ARTIs has been shown to occur more frequently in urgent care than other outpatient se... | null | 0.359 | 34 | Nursing; Medicine | Medicine; Nursing | 2,022 |
35,471,670 | Metabolic syndrome may be more frequent in treatment-naive sarcoidosis patients. | Zeitschrift fur Rheumatologie | Z Rheumatol | 83 | Suppl 1 | 10.1007/s00393-022-01210-8 | eng | 2,024 | 2 | null | 2,022 | 4 | 26 | [INTRODUCTION] Sarcoidosis is a chronic granulomatous multisystem inflammatory disease. An association between sarcoidosis and subclinical atherosclerosis has recently been demonstrated. However, there are limited publications on metabolic syndrome (MetS) and its metabolic changes in sarcoidosis. In this study, we eval... | Cardiovasculer diseases; Metabolic syndrome; Obesity; Rheumatoid arthritis; Sarcoidosis | 0.261 | 43 | Rheumatology | Medicine | 2,024 |
35,471,462 | Child and caregiver perspectives on access to psychosocial and educational support in pediatric chronic kidney disease: a focus group study. | Pediatric nephrology (Berlin, Germany) | Pediatr Nephrol | 38 | 1 | 10.1007/s00467-022-05551-z | eng | 2,023 | 1 | null | 2,022 | 4 | 26 | [BACKGROUND] Children with chronic kidney disease (CKD) generally have worse educational and psychosocial outcomes compared with their healthy peers. This can impair their ability to manage their treatment, which in turn can have long-term health consequences through to adulthood. We attempted to capture the experience... | Adolescence; Chronic kidney disease; Education; Mental health; Psychosocial | 0.785 | 128 | Pediatrics, Perinatology and Child Health; Nephrology | Medicine | 2,023 |
35,470,913 | Concomitant aortic valve repair for aortic insufficiency and implantation of left ventricle mechanical support. | Journal of cardiac surgery | J Card Surg | 37 | 7 | 10.1111/jocs.16547 | eng | 2,022 | 7 | null | 2,022 | 4 | 26 | [BACKGROUND] Moderate to severe aortic valve insufficiency (AI) in patients undergoing left ventricular assist device (LVAD) implantation is a significant complication which occurs in up to 10.7% of patients in the INTERMACS database and has profound consequences for survival. Preoperative Impella use is associaed with... | HAART Ring; LVAD; aortic valve regurgitation; aortic valve repair; complications; heart failure; nonischemic cardiomyopathy | 0.445 | 69 | Surgery; Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,022 |
35,470,850 | Downregulating HK2 inhibits proliferation of endometrial stromal cells through a noncanonical pathway involving phosphorylation of signal transducer and activator of transcription 1 in endometriosis. | Biology of reproduction | Biol Reprod | 107 | 2 | 10.1093/biolre/ioac081 | eng | 2,022 | 8 | 9 | null | null | null | [BACKGROUND] Endometriosis is a benign gynecologic disease that causes chronic pelvic pain, dysmenorrhea and infertility and shares several characteristics with malignant tumors, afflicting women of reproductive age. Hexokinase 2 plays an essential role as the first rate-limiting enzyme in the metabolic glycolysis path... | HK2; STAT1; endometrial stromal cells; endometriosis; glycolysis | null | null | null | null | null |
35,470,160 | 2022 EULAR points to consider for remote care in rheumatic and musculoskeletal diseases. | Annals of the rheumatic diseases | Ann Rheum Dis | 81 | 8 | 10.1136/annrheumdis-2022-222341 | eng | 2,022 | 8 | null | 2,022 | 4 | 25 | [BACKGROUND] Remote care and telehealth have the potential to expand healthcare access, and the COVID-19 pandemic has called for alternative solutions to conventional face-to-face follow-up and monitoring. However, guidance is needed on the integration of telehealth into clinical care of people with rheumatic and muscu... | Epidemiology; Health services research; Patient Care Team | 6.489 | 300 | Biochemistry, Genetics and Molecular Biology; Immunology; Immunology and Allergy; Rheumatology | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,022 |
35,470,017 | Systematic review of vascular surgery recruitment strategies for medical students and general surgery residents. | Journal of vascular surgery | J Vasc Surg | 76 | 3 | 10.1016/j.jvs.2022.03.875 | eng | 2,022 | 9 | null | 2,022 | 4 | 22 | [OBJECTIVES] Recruitment into the vascular surgery specialty is an imperative as the specialty faces significant demographic changes. Due to the changing dynamics in vascular surgery training pathways, we sought to review current literature on recruitment strategies and their effectiveness with medical students and gen... | Fellowship; Recruitment; Residency; Surgical education; Systematic review | 2.027 | 225 | Cardiology and Cardiovascular Medicine; Surgery | Medicine | 2,022 |
35,469,994 | Arthroscopic Latarjet for Primary Shoulder Instability With Off-Track Lesions or Revision Surgery Yields Satisfactory Clinical Results and Reliable Return to Sport and Work at Minimum 3-Year Follow-Up. | Arthroscopy : the journal of arthroscopic related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association | Arthroscopy | 38 | 10 | 10.1016/j.arthro.2022.04.004 | eng | 2,022 | 10 | null | 2,022 | 4 | 22 | [PURPOSE] To retrospectively evaluate clinical and radiologic outcomes and return to sport and to work of patients after arthroscopic Latarjet stabilization for primary instability or revision surgery; factors influencing and determining results and potential predictors for clinical outcomes also were evaluated. [METHO... | null | null | null | null | null | null |
35,469,934 | Left atrial contractile strain predicts recurrence of atrial tachyarrhythmia after catheter ablation. | International journal of cardiology | Int J Cardiol | 358 | null | 10.1016/j.ijcard.2022.04.056 | eng | 2,022 | 7 | 1 | 2,022 | 4 | 22 | [BACKGROUND] Despite improvement in treatment strategies of atrial fibrillation (AF), a considerable number of patients still experience recurrence of atrial tachyarrhythmia (ATA) following catheter ablation (CA). This study aimed to investigate the prognostic value of left atrial (LA) deformation analysis in a large g... | Atrial fibrillation; Catheter ablation; Left atrial strain; Speckle tracking echocardiography | 1.122 | 155 | Cardiology and Cardiovascular Medicine | Medicine | 2,022 |
35,469,897 | PSMA-PET- and MRI-Based Focal Dose Escalated Radiation Therapy of Primary Prostate Cancer: Planned Safety Analysis of a Nonrandomized 2-Armed Phase 2 Trial (ARO2020-01). | International journal of radiation oncology, biology, physics | Int J Radiat Oncol Biol Phys | 113 | 5 | 10.1016/j.ijrobp.2022.04.020 | eng | 2,022 | 8 | 1 | 2,022 | 4 | 22 | [PURPOSE] The bicentric HypoFocal phase 2 trial investigates the implementation of molecular imaging with positron-emission tomography targeting prostate-specific membrane antigen (PSMA-PET) into modern focal dose-escalation radiation therapy (RT) concepts in 2 nonrandomized arms. We present the planned safety analysis... | null | 2.09 | 286 | Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging | Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy | 2,022 |
35,469,731 | Dietary calcium intake in relation to blood lipids and lipoproteins profiles: A systematic review and meta-analysis of epidemiologic studies. | Nutrition, metabolism, and cardiovascular diseases : NMCD | Nutr Metab Cardiovasc Dis | 32 | 7 | 10.1016/j.numecd.2022.03.018 | eng | 2,022 | 7 | null | 2,022 | 3 | 24 | [AIMS] Findings of prior investigations on the association between calcium intake and lipid profiles were inconsistent. We performed a systematic review and meta-analysis on epidemiologic studies to evaluate the relationship of dietary calcium intake with blood lipids and lipoproteins. [DATA SYNTHESIS] A systematic sea... | Calcium intake; Lipid profiles; Meta-analysis; Systematic review | 0.997 | 125 | Cardiology and Cardiovascular Medicine; Medicine; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism | Medicine; Nursing | 2,022 |
35,469,578 | AZD4547 and the Alleviation of Hepatoma Cell Sorafenib Resistance via the Promotion of Autophagy. | Anti-cancer agents in medicinal chemistry | Anticancer Agents Med Chem | 22 | 18 | 10.2174/1871520622666220425124419 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] This study is part of a larger research effort to explore the molecular mechanism of hepatocellular carcinoma, reduce drug resistance and seek new targets. [OBJECTIVE] The objective of this study is to investigate the effect and mechanism of fibroblast growth factor receptor inhibitor AZD4547 on Sorafenib-... | Hepatoma; Sorafenib; Toll-like receptor 4; autophagy; drug resistance; fibroblast growth factor receptor | null | null | null | null | null |
35,469,522 | The role of neoadjuvant conventional transarterial chemoembolization with radiofrequency ablation in the treatment of recurrent hepatocellular carcinoma after initial hepatectomy with microvascular invasion. | International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group | Int J Hyperthermia | 39 | 1 | 10.1080/02656736.2022.2051613 | eng | 2,022 | null | null | null | null | null | [OBJECTIVES] Recurrent hepatocellular carcinoma (HCC) patients with microvascular invasion (MVI)-positive primary tumor is at high risk of re-recurrence while treated with radiofrequency ablation (RFA). We aimed to investigate whether neoadjuvant conventional transarterial chemoembolization (cTACE) was effective in red... | Neoadjuvant treatment; hepatocellular carcinoma; microvascular invasion; radiofrequency ablation; transarterial chemoembolization | 0.762 | 103 | Medicine; Physiology; Physiology; Radiological and Ultrasound Technology; Cancer Research | Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine | 2,022 |
35,469,517 | An inter-professional student-run medication review programme. Reducing adverse drug reactions in a memory outpatient clinic: a controlled clinical trial. | Expert opinion on drug safety | Expert Opin Drug Saf | 21 | 12 | 10.1080/14740338.2022.2069748 | eng | 2,022 | 12 | null | 2,022 | 4 | 28 | [BACKGROUND] We investigated if the addition of an inter-professional student-led medication review team (ISP-team) to standard care can increase the number of detected ADRs and reduce the number of ADRs 3 months after an outpatient visit. [RESEARCH DESIGN AND METHODS] In this controlled clinical trial, patients were a... | Medication safety; elderly care; optimizing medication safety; pharmacotherapy; pharmacovigilance | 0.773 | 96 | Medicine; Pharmacology | Medicine | 2,022 |
35,469,091 | Randomised clinical trial: effect of adding branched chain amino acids to exercise and standard-of-care on muscle mass in cirrhotic patients with sarcopenia. | Hepatology international | Hepatol Int | 16 | 3 | 10.1007/s12072-022-10334-7 | eng | 2,022 | 6 | null | 2,022 | 4 | 25 | [BACKGROUND] The role of branched-chain amino acids (BCAA) in improving muscle mass in cirrhosis is presently debatable. [AIMS] To evaluate the role of BCAA in improving muscle mass in a double-blind randomized placebo-controlled trial in patients with cirrhosis having sarcopenia. [METHODS] Consecutive patients with ci... | End-stage liver disease; Exercise; Leucine; Malnutrition; Quality of life | 1.577 | 70 | Hepatology | Medicine | 2,022 |
35,468,721 | MAPKAPK5-AS1 drives the progression of hepatocellular carcinoma via regulating miR-429/ZEB1 axis. | BMC molecular and cell biology | BMC Mol Cell Biol | 23 | 1 | 10.1186/s12860-022-00420-x | eng | 2,022 | 4 | 25 | 2,022 | 4 | 25 | [BACKGROUND] Hepatocellular carcinoma (HCC) is a common malignancy. Long non-coding RNAs (lncRNAs) partake in the progression of HCC. However, the role of lncRNA MAPKAPK5-AS1 in the development of HCC has not been fully clarified. [METHODS] RNA sequencing data and quantitative real-time polymerase chain reaction (qRT-P... | Hepatocellular carcinoma; MAPKAPK5-AS1; ZEB1; miR-429 | null | null | null | null | null |
35,468,568 | Multiple sclerosis lesions and atrophy in the spinal cord: Distribution across vertebral levels and correlation with disability. | NeuroImage. Clinical | Neuroimage Clin | 34 | null | 10.1016/j.nicl.2022.103006 | eng | 2,022 | null | null | 2,022 | 4 | 13 | [BACKGROUND] The vast majority of magnetic resonance imaging (MRI) studies on multiple sclerosis (MS) covered the spinal cord (SC), if at all, incompletely. [OBJECTIVE] To assess SC involvement in MS, as detectable by whole SC MRI, with regard to distribution across vertebral levels and relation to clinical phenotypes ... | Multiple sclerosis; Spinal cord; Spinal cord atrophy; Spinal cord lesions | null | null | null | null | null |
35,466,697 | Effectiveness and Safety of Lower Dose of Rivaroxaban for Cancer-Related Venous Thromboembolism: A Retrospective Cohort Study. | The Annals of pharmacotherapy | Ann Pharmacother | 56 | 12 | 10.1177/10600280221084418 | eng | 2,022 | 12 | null | 2,022 | 4 | 25 | [BACKGROUND] Primary and recurrent venous thromboembolism (VTE) commonly occur in patients with cancer. However, because of the National Health Insurance regulations, available dosage forms, and clinical conditions, the prescribed dose of rivaroxaban may not be consistent with its recommended dose. [OBJECTIVE] To evalu... | Anti-factor Xa; anticoagulants; cancer; clinical pharmacy; drug utilization evaluation | 0.891 | 125 | Medicine; Pharmacology | Medicine | 2,022 |
35,466,628 | Variety Of Gastrointestinal Duplications In Children: Experience At Tertiary Care Hospital. | Journal of Ayub Medical College, Abbottabad : JAMC | J Ayub Med Coll Abbottabad | 34 | 1 | 10.55519/JAMC-01-8870 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Gastrointestinal duplication is a rare developmental anomaly that can be present anywhere along the GI tract, most often being found in ileum. The purpose of this study is to share our experience in evaluation of the presentation, investigations, management challenges and complications of patients with thi... | null | null | null | null | null | null |
35,466,510 | Mobile shopping beauty live commerce changes in COVID-19 pandemic focused on fun contents of MZ generation in Republic of Korea. | Journal of cosmetic dermatology | J Cosmet Dermatol | 21 | 6 | 10.1111/jocd.14442 | eng | 2,022 | 6 | null | 2,022 | 4 | 24 | [BACKGROUND] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the new virus responsible for the coronavirus disease 2019 (COVID-19) pandemic. According to these circumstances, a study was conducted to prepare a long-term non-face-to-face outpatient treatment service during the COVID-19 pandemic. Given th... | COVID-19; Fun; MZ generation; live commerce; mobile shopping | 0.61 | 67 | Dermatology | Medicine | 2,022 |
35,466,311 | Prevalence and Clinician Recognition of Avoidant/Restrictive Food Intake Disorder in Patients With Inflammatory Bowel Disease. | Gastroenterology hepatology | Gastroenterol Hepatol (N Y) | 17 | 11 | null | eng | 2,021 | 11 | null | null | null | null | [BACKGROUND] Avoidant/restrictive food intake disorder (ARFID) is a newly described eating disorder. The aims of this study were to evaluate the prevalence of ARFID in patients with inflammatory bowel disease (IBD) and assess provider recognition of an eating disorder in these patients. [METHODS] One hundred patients w... | Inflammatory bowel disease; avoidant/restrictive food intake disorder; eating disorders | null | null | null | null | null |
35,466,109 | Effects of Subdiaphragmatic Vagotomy in the MPTP-induced Neurotoxicity in the Striatum and Colon of Mice. | Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology | Clin Psychopharmacol Neurosci | 20 | 2 | 10.9758/cpn.2022.20.2.389 | eng | 2,022 | 5 | 31 | null | null | null | [OBJECTIVE] Gut-microbiota-brain axis plays a role in the pathogenesis of Parkinson's disease (PD). The subdiaphragmatic vagus nerve serves as a major modulatory pathway between the gut microbiota and the brain. However, the role of subdiaphragmatic vagus nerve in PD pathogenesis are unknown. Here, we investigated the ... | Alpha-synuclein; Brain; Colon; MPTP; Vagus nerve | 0.74 | 47 | Pharmacology; Psychiatry and Mental Health; Behavioral Neuroscience | Medicine; Neuroscience | 2,022 |
35,465,979 | Impact of COVID-19 vaccine-associated side effects on health care worker absenteeism and future booster vaccination. | Vaccine | Vaccine | 40 | 23 | 10.1016/j.vaccine.2022.04.046 | eng | 2,022 | 5 | 20 | 2,022 | 4 | 18 | [BACKGROUND] Short-term side effects related to mRNA vaccines against SARS-CoV-2 are frequent and bothersome, with the potential to disrupt work duties and impact future vaccine decision-making. [OBJECTIVE] To identify factors more likely to lead to vaccine-associated work disruption, employee absenteeism, and future v... | Absenteeism; Booster; COVID-19; Healthcare worker; Hesitancy; Side-effects; Vaccine | 1.493 | 222 | Immunology and Microbiology; Infectious Diseases; Molecular Medicine; Public Health, Environmental and Occupational Health; Veterinary | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Veterinary | 2,022 |
35,465,437 | How to Identify the Indications for Early Intervention in Acute Necrotizing Pancreatitis Patients: A Long-Term Follow-Up Study. | Frontiers in surgery | Front Surg | 9 | null | 10.3389/fsurg.2022.842016 | eng | 2,022 | null | null | 2,022 | 4 | 6 | [AIM] To explore the indications for early intervention in patients with acute necrotizing pancreatitis (ANP) and evaluate the effect of early intervention on the prognosis of ANP patients. [METHODS] The clinical data of patients with ANP who underwent general surgery at Xuanwu Hospital of Capital Medical University fr... | acute necrotizing pancreatitis; complications; infected pancreatic necrosis; percutaneous drainage; persistent organ failure | 0.459 | 48 | Surgery | Medicine | 2,022 |
35,465,426 | Application of Narrative Nursing Combined With Focused Solution Model to Anxiety and Depression in Patients With Lung Tumor During Perioperative Period. | Frontiers in surgery | Front Surg | 9 | null | 10.3389/fsurg.2022.858506 | eng | 2,022 | null | null | 2,022 | 4 | 8 | [BACKGROUND] In the face of the dual pressure of disease and operation, patients with lung tumors in the perioperative period often have adverse psychological states such as anxiety and depression. There are many risk factors affecting the psychological state of patients in the perioperative period, and there is still ... | anxiety; depression; focus resolution mode; lung tumor; narrative care | 0.459 | 48 | Surgery | Medicine | 2,022 |
35,465,378 | A cross-sectional regional study looking at the factors responsible for the low COVID-19 vaccination rate in Nigeria. | The Pan African medical journal | Pan Afr Med J | 41 | null | 10.11604/pamj.2022.41.114.30767 | eng | 2,022 | null | null | 2,022 | 2 | 9 | [INTRODUCTION] COVID-19 vaccination has been rolled out in Nigeria, with low uptake often attributed to shortage of the vaccine. We set out to find out the current trend so far and to the best of our knowledge, our study is one of the early studies since the roll out in the region looking at the real situation on groun... | COVID-19 vaccine hesitancy; COVID-19 virus; public health | 0.33 | 53 | Medicine | Medicine | 2,022 |
35,465,144 | Seasonal Variability Influence on the Prevalence of Diarrhoea among Under-Five-Year-old Children in Kersa District, Eastern Ethiopia: A Community-Based Longitudinal Study. | Environmental health insights | Environ Health Insights | 16 | null | 10.1177/11786302221093480 | eng | 2,022 | null | null | 2,022 | 4 | 17 | [BACKGROUND] The health effects of climate change have been found to be a global concern for the last 2 centuries. However, the effect of climate variability on diarrhoea among under-five-year-old children is perhaps undocumented or otherwise unknown. The aim of the present study was to determine the effect of climate ... | Climate variability; Ethiopia; Under five children; diarrhoea | 0.498 | 32 | Management, Monitoring, Policy and Law; Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health | Environmental Science; Medicine | 2,022 |
35,465,083 | Procedural Safety and Long-Term Clinical Outcomes in Patients Receiving Ultra-Long Everolimus-Eluting Stent: A Single-Center Real-World Experience. | Cardiology research | Cardiol Res | 13 | 2 | 10.14740/cr1357 | eng | 2,022 | 4 | null | 2,022 | 4 | 5 | [BACKGROUND] Diffuse long coronary lesions are difficult to treat percutaneously. The aim of the present study was to assess the procedural safety and long-term efficacy of the ultra-long (48-mm) drug-eluting stent Xience Xpedition. [METHODS] This was an investigator-initiated, observational, all-comers study. A total ... | 48-mm stent; Coronary artery disease; Percutaneous coronary intervention; Xience | 0.46 | 13 | Cardiology and Cardiovascular Medicine | Medicine | 2,022 |
35,464,939 | Active Surveillance Cultures and Procalcitonin in Combination With Clinical Data to Guide Empirical Antimicrobial Therapy in Hospitalized Medical Patients With Sepsis. | Frontiers in microbiology | Front Microbiol | 13 | null | 10.3389/fmicb.2022.797932 | eng | 2,022 | null | null | 2,022 | 4 | 7 | [OBJECTIVE] The prevalence of colonization with multidrug-resistant organisms (MDRO) has increased over the last decade, reaching levels as high as 23% in certain patient populations. Active surveillance cultures (ASC) represent a valuable tool to identify patients colonized with MDRO to apply preventive measures, redu... | MDRO colonization; Sequential Organ Failure Assessment (SOFA); antimicrobial resistance (AMR); nasal and rectal surveillance swab; procalcitonin; quick Sequential Organ Failure Assessment (qSOFA); sepsis; systemic inflammatory response syndrome (SIRS) | 1.19 | 259 | Microbiology; Microbiology | Immunology and Microbiology; Medicine | 2,022 |
35,464,709 | Stigma towards health care providers taking care of COVID-19 patients: A multi-country study. | Heliyon | Heliyon | 8 | 4 | 10.1016/j.heliyon.2022.e09300 | eng | 2,022 | 4 | null | 2,022 | 4 | 18 | [BACKGROUND] Health care providers (HCPs) have always been a common target of stigmatization during widespread infections and COVID-19 is not an exception. [AIM] This study aims to investigate the prevalence of stigmatization during the COVID-19 pandemic among HCPs in seven different countries using the Stigma COVID-19... | COVID-19; Healthcare providers; Mental health; S19-HCPs; Stigma | 0.609 | 115 | Multidisciplinary | Multidisciplinary | 2,022 |
35,464,254 | Effectiveness of Antimicrobial Stewardship Program in Long-Term Care: A Five-Year Prospective Single-Center Study. | Interdisciplinary perspectives on infectious diseases | Interdiscip Perspect Infect Dis | 2022 | null | 10.1155/2022/8140429 | eng | 2,022 | null | null | 2,022 | 4 | 12 | [OBJECTIVE] To report the effectiveness of the antimicrobial stewardship program (ASP) in a long-term care (LTC) facility, by analyzing the change in antimicrobial consumption and cost and multidrug resistance (MDR) rates over a 5-year period. [METHOD] A prospective interventional study was conducted at a 106-bed facil... | null | 0.573 | 37 | Parasitology; Infectious Diseases; Microbiology; Microbiology; Virology | Immunology and Microbiology; Medicine | 2,022 |
35,464,101 | Current Implementation of Digital Dentistry for Removable Prosthodontics in US Dental Schools. | International journal of dentistry | Int J Dent | 2022 | null | 10.1155/2022/7331185 | eng | 2,022 | null | null | 2,022 | 4 | 15 | [OBJECTIVES] Although digital technology has been widely integrated into dental education, there is limited literature investigating the extent of the integration of computer-aided design and computer-aided manufacturing (CAD-CAM) for removable systems in the dental curriculum. The purpose of this study was to assess t... | null | 0.47 | 57 | Dentistry | Dentistry | 2,022 |
35,463,905 | A Study to Evaluate Accuracy and Validity of the EFAI Computer-Aided Bone Age Diagnosis System Compared With Qualified Physicians. | Frontiers in pediatrics | Front Pediatr | 10 | null | 10.3389/fped.2022.829372 | eng | 2,022 | null | null | 2,022 | 4 | 8 | [STUDY OBJECTIVES] In previous research, we built a deep neural network model based on Inception-Resnet-v2 to predict bone age (EFAI-BAA). The primary objective of the study was to determine if the EFAI-BAA was substantially concordant with the qualified physicians in assessing bone ages. The secondary objective of the... | artificial intelligence; bone age assessment; clinical practice; concordance correlation coefficient (CCC); deep learning | 0.798 | 83 | Pediatrics, Perinatology and Child Health | Medicine | 2,022 |
35,463,844 | Cauda Equina Syndrome Following Lumbar Disc Herniation at L5-S1: A Case Report. | Journal of chiropractic medicine | J Chiropr Med | 20 | 3 | 10.1016/j.jcm.2021.12.007 | eng | 2,021 | 9 | null | 2,022 | 4 | 6 | [OBJECTIVE] The purpose of this article is to describe a patient presenting to a chiropractic clinic with rapidly progressing cauda equina symptoms. [CLINICAL FEATURES] A 30-year-old woman presented to a chiropractic clinic with the onset of saddle distribution sensory loss and urinary retention. The patient had worsen... | Cauda Equina Syndrome; Chiropractic; Low Back Pain; Radiculopathy; Spinal Stenosis | 0.264 | 33 | Chiropractics | Health Professions | 2,021 |
35,463,749 | Metabolomics Fingerprint Predicts Risk of Death in Dilated Cardiomyopathy and Heart Failure. | Frontiers in cardiovascular medicine | Front Cardiovasc Med | 9 | null | 10.3389/fcvm.2022.851905 | eng | 2,022 | null | null | 2,022 | 4 | 7 | [BACKGROUND] Heart failure (HF) is a leading cause of morbidity and mortality worldwide. Metabolomics may help refine risk assessment and potentially guide HF management, but dedicated studies are few. This study aims at stratifying the long-term risk of death in a cohort of patients affected by HF due to dilated cardi... | NMR spectroscopy; heart failure; metabolomics; precision medicine; prognosis | 1.391 | 81 | Cardiology and Cardiovascular Medicine | Medicine | 2,022 |
35,463,080 | Efficacy and Safety of Xiaoyao Recipe in the Treatment of Poststroke Depression: A Systematic Review and Meta-Analysis. | Evidence-based complementary and alternative medicine : eCAM | Evid Based Complement Alternat Med | 2022 | null | 10.1155/2022/4385783 | eng | 2,022 | null | null | 2,022 | 4 | 13 | [BACKGROUND] Poststroke depression (PSD) is a common neuropsychiatric disorder that affects the disability, mortality, functional recovery, and quality of daily life of patients. Xiaoyao Recipe (XYR) is often used to treat PSD and has achieved good clinical effects, but it lacks reliable evidence. [OBJECTIVE] This stud... | null | null | null | null | null | null |
35,462,694 | Dysfunction in the Interaction of Information Between and Within the Bilateral Primary Sensory Cortex. | Frontiers in aging neuroscience | Front Aging Neurosci | 14 | null | 10.3389/fnagi.2022.862107 | eng | 2,022 | null | null | 2,022 | 4 | 8 | [BACKGROUND] Interhemispheric and intrahemispheric long-range synchronization and information communication are crucial features of functional integration between the bilateral hemispheres. Previous studies have demonstrated that disrupted functional connectivity (FC) exists in the bilateral hemispheres of patients wit... | carpal tunnel syndrome; effective connectivity; functional connectivity; interhemispheric; primary sensory cortex; voxel-mirrored homotopic connectivity | 1.211 | 135 | Aging; Cognitive Neuroscience | Biochemistry, Genetics and Molecular Biology; Neuroscience | 2,022 |
35,462,454 | Screening check test to confirm the relative reactivity and applicability of 2,4-dinitrophenylhydrazine impregnated-filters for formaldehyde on other compounds. | Journal of occupational health | J Occup Health | 64 | 1 | 10.1002/1348-9585.12333 | eng | 2,022 | 1 | null | null | null | null | [OBJECTIVES] A simple check test method was designed to confirm whether a 2,4-dinitrophenylhydrazine (DNPH) filter for formaldehyde can be used to measure other compounds. [METHODS] Sample mixtures containing the same concentrations of formaldehyde, acetaldehyde, and acetone were spiked to the DNPH-filter, extracted, a... | DNPH; aldehyde; ketone; passive sampler; reactivity screening | 0.689 | 73 | Public Health, Environmental and Occupational Health | Medicine | 2,022 |
35,462,413 | Elucidation of the impact of four different drying methods on the phenolics, volatiles, and color properties of the peels of four types of citrus fruits. | Journal of the science of food and agriculture | J Sci Food Agric | 102 | 13 | 10.1002/jsfa.11956 | eng | 2,022 | 10 | null | 2,022 | 5 | 30 | [BACKGROUND] Citrus fruit peels are considered to be process waste in the fruit juice industry but they are a valuable raw material due to their volatile and bioactive components. Drying is one of the most common methods to preserve this material. In this study, four drying processes were applied to the peels of four k... | citrus peel; color; drying; microstructure; phenolics; volatiles | null | null | null | null | null |
35,462,384 | Effect of an Educational Video and Information Pamphlet on Knowledge and Attitudes About Electroconvulsive Therapy: A Randomized, Blind, Controlled Study. | The journal of ECT | J ECT | 38 | 3 | 10.1097/YCT.0000000000000848 | eng | 2,022 | 9 | 1 | 2,022 | 4 | 14 | [OBJECTIVE] Electroconvulsive therapy (ECT) is considered an effective, yet underused and stigmatized form of psychiatric treatment. Public misconception can impact informed decision making, and therefore, it is important to educate the community with accurate and realistic representations of modern ECT. The aim of thi... | null | null | null | null | null | null |
35,462,146 | Placenta percreta as a cause of uterine rupture in the second trimester: Case report. | International journal of surgery case reports | Int J Surg Case Rep | 94 | null | 10.1016/j.ijscr.2022.107069 | eng | 2,022 | 5 | null | 2,022 | 4 | 11 | [INTRODUCTION] Placenta accreta spectrum is a very life-threatening obstetrical condition whose rate increased significantly the past years due to the increase of caesarean deliveries. In some rare cases, it can cause uterine rupture which needs to be diagnosed and managed quickly to avoid catastrophic outcomes. [CASE ... | Case report; Haemoperitoneum; Hysterectomy; Placenta percreta; Pregnancy; Uterine rupture | 0.193 | 31 | Surgery | Medicine | 2,022 |
35,461,841 | Association between outdoor artificial light at night and sleep duration among older adults in China: A cross-sectional study. | Environmental research | Environ Res | 212 | Pt B | 10.1016/j.envres.2022.113343 | eng | 2,022 | 9 | null | 2,022 | 4 | 21 | [BACKGROUND] Light after dusk disrupts the circadian rhythms and shifts the timing of sleep later; but it is unknown whether outdoor artificial light at night (ALAN) affects sleep quality. This study aimed to explore the association between residential outdoor ALAN and sleep duration in a nationally representative samp... | ALAN; China; Nighttime light; Outdoor light; Sleep; Sleep duration | 1.635 | 196 | Biochemistry; Environmental Science | Biochemistry, Genetics and Molecular Biology; Environmental Science | 2,022 |
35,460,538 | Identification of the regulatory role of the circ_0004788/miR-515-5p/FGF2 network in nasopharyngeal carcinoma development. | Head neck | Head Neck | 44 | 7 | 10.1002/hed.27066 | eng | 2,022 | 7 | null | 2,022 | 4 | 23 | [BACKGROUND] CircularRNAs (circRNAs) played vital roles in nasopharyngeal carcinoma (NPC). However, the impacts of circ_0004788 on the development of NPC have not been explored. [METHODS] Cell counting kit-8 (CCK-8), 5-Ethynyl-2'-deoxyuridine (EdU) and colony formation assays were applied to determine cell proliferatio... | FGF2; circ_0004788; miR-515-5p; nasopharyngeal carcinoma | null | null | null | null | null |
35,460,496 | Oral sequential therapy in the treatment of post-surgical epidural abscess and subdural empyema. | Infection | Infection | 50 | 5 | 10.1007/s15010-022-01814-x | eng | 2,022 | 10 | null | 2,022 | 4 | 23 | [PURPOSE] The management of post-surgical subdural empyema and subdural abscess is not standardised. The objective was to analyse the efficacy and safety of oral sequential therapy (OST). [METHODS] Retrospective observational study in a tertiary hospital in Vigo (Spain). We included adult patients with subdural abscess... | And safety; Intracranial epidural abscess; Oral sequential therapy; Subdural empyema; Surgical infection | 1.488 | 94 | Infectious Diseases; Medicine; Microbiology | Medicine | 2,022 |
35,460,250 | Expression-based Genome-wide Association Study Links OPN and IL1-RA With Newly Diagnosed Type 1 Diabetes in Children. | The Journal of clinical endocrinology and metabolism | J Clin Endocrinol Metab | 107 | 7 | 10.1210/clinem/dgac256 | eng | 2,022 | 6 | 16 | null | null | null | [CONTEXT] Islet autoantibodies (IAbs) are currently the most reliable indicators of islet autoimmunity. However, IAbs do not fully meet the need for the prediction and intervention of type 1 diabetes (T1D). Serological proteins should be great sources for biomarkers. [OBJECTIVE] This work aimed to identify new proteomi... | IL1-RA; biomarker; eGWAS; osteopontin; proteomics; type 1 diabetes | 1.776 | 400 | Biochemistry; Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,460,240 | Baseline factors associated with self-reported disease flares following COVID-19 vaccination among adults with systemic rheumatic disease: results from the COVID-19 global rheumatology alliance vaccine survey. | Rheumatology (Oxford, England) | Rheumatology (Oxford) | 61 | SI2 | 10.1093/rheumatology/keac249 | eng | 2,022 | 6 | 28 | null | null | null | [OBJECTIVE] To examine the frequency of, and risk factors for, disease flare following COVID-19 vaccination in patients with systemic rheumatic disease (SRD). [METHODS] An international study was conducted from 2 April to 16 August 2021, using an online survey of 5619 adults with SRD for adverse events following COVID-... | COVID-19; disease flare; systemic rheumatic diseases; vaccine | 1.721 | 205 | Pharmacology; Rheumatology | Medicine | 2,022 |
35,460,174 | Hepatic exosomes with declined MiR-27b-3p trigger RIG-I/TBK1 signal pathway in macrophages. | Liver international : official journal of the International Association for the Study of the Liver | Liver Int | 42 | 7 | 10.1111/liv.15281 | eng | 2,022 | 7 | null | 2,022 | 5 | 11 | [BACKGROUND AND AIMS] Evidence suggests that interferon alpha (IFNα) plays an essential role in decreasing the HBsAg quantification and elevating the rate of clinical cure in chronic hepatitis B (CHB). However, the mechanisms underlying the effects of the exosomes on the expression of host genes in IFNα treatment remai... | HBsAg; exosome; host immune; interferon alpha; miR-27b-3p | 1.929 | 145 | Hepatology | Medicine | 2,022 |
35,459,986 | Reference equations for the six-minute walking distance in obese Chinese subjects more than 40 years old. | Eating and weight disorders : EWD | Eat Weight Disord | 27 | 7 | 10.1007/s40519-022-01404-8 | eng | 2,022 | 10 | null | 2,022 | 4 | 22 | [BACKGROUND] Studies have shown that the reference equations for the six-minute walking distance (6MWD), which were mainly derived from healthy, normal-weight people, are not suitable for individuals with obesity. The main purpose of this study was to establish reference equations for the 6MWD in obese Chinese subjects... | Exercise testing; Obese people; Reference equation; Six-minute walking test | 0.724 | 66 | Clinical Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,022 |
35,459,755 | Distribution of HIV self-tests by men who have sex with men attending a French sexual health centre: results of the OTO study. | Sexually transmitted infections | Sex Transm Infect | 99 | 2 | 10.1136/sextrans-2022-055417 | eng | 2,023 | 3 | null | 2,022 | 4 | 22 | [OBJECTIVES] HIV self-tests (HSTs) have been deployed to reduce the burden of undiagnosed HIV infections in subpopulations undertested. We assumed that patients attending sexual health centres could themselves distribute HSTs in their close network. This study aimed to assess the proportion and the characteristics of t... | HIV; Homosexuality, Male; Point-of-Care Testing | 1.04 | 115 | Dermatology; Infectious Diseases | Medicine | 2,023 |
35,459,610 | Systematic Review and Meta-Analysis of Outcomes After Operative Treatment of Aberrant Subclavian Artery Pathologies and Suggested Reporting Items. | European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery | Eur J Vasc Endovasc Surg | 63 | 5 | 10.1016/j.ejvs.2022.02.027 | eng | 2,022 | 5 | null | 2,022 | 2 | 25 | [OBJECTIVE] To synthesise and present all available evidence regarding the surgical treatment of patients with aberrant subclavian artery (aSA) pathologies during the last 30 years. The study also aimed to create a checklist of suggested reporting items to help increase reporting homogeneity. [METHODS] A systematic sea... | Aberrant subclavian artery; Arteria lusoria; Dysphagia lusoria; Open aortic repair; Suggested reporting items checklist; TEVAR | 1.341 | 144 | Cardiology and Cardiovascular Medicine; Surgery | Medicine | 2,022 |
35,459,601 | Bibliometric study of refractive surgery and dry eye scientific literature. | Archivos de la Sociedad Espanola de Oftalmologia | Arch Soc Esp Oftalmol (Engl Ed) | 97 | 6 | 10.1016/j.oftale.2022.02.011 | eng | 2,022 | 6 | null | 2,022 | 4 | 19 | [OBJECTIVE] Currently, refractive surgery is a safe and effective procedure, and considered as a risk for development of dry eye. The aim of study is to analyze the scientific publications in the field of ocular dryness secondary to refractive surgery through a bibliometric approach. The temporal period goes since 2001... | Bibliometric; Dry eye; Lotka; Ojo seco; Price; Refractive surgery | 0.218 | 27 | Ophthalmology | Medicine | 2,022 |
35,459,254 | IFI16 induces inflammation in hepatitis B virus-associated glomerulonephritis by regulating the Caspase-1/ IL-1 ß pathway. | Diagnostic pathology | Diagn Pathol | 17 | 1 | 10.1186/s13000-022-01220-9 | eng | 2,022 | 4 | 23 | 2,022 | 4 | 23 | [AIMS AND BACKGROUND] IFI16 plays an important role in innate immunity against invasive microbial infection by sensing double-stranded DNA viruses due to caspase-1-dependent inflammasome activation and subsequent maturation and secretion of IL-1β. However, the role of IFI16 in regulating the immune response to viruses ... | Caspase-1; HBV-DNA; HBV-GN; IFI16 | 0.677 | 66 | Histology; Medicine; Pathology and Forensic Medicine | Medicine | 2,022 |
35,459,146 | Monoexponential, biexponential and diffusion kurtosis MR imaging models: quantitative biomarkers in the diagnosis of placenta accreta spectrum disorders. | BMC pregnancy and childbirth | BMC Pregnancy Childbirth | 22 | 1 | 10.1186/s12884-022-04644-9 | eng | 2,022 | 4 | 22 | 2,022 | 4 | 22 | [BACKGROUND] To investigate the diagnostic value of monoexponential, biexponential, and diffusion kurtosis MR imaging (MRI) in differentiating placenta accreta spectrum (PAS) disorders. [METHODS] A total of 65 patients with PAS disorders and 27 patients with normal placentas undergoing conventional DWI, IVIM, and DKI w... | Diffusion kurtosis imaging; Diffusion-weighted MRI; Intravoxel incoherent motion; PAS disorders | 1.034 | 122 | Obstetrics and Gynecology | Medicine | 2,022 |
35,459,093 | Transcriptome-based biomarker gene screening and evaluation of the extracellular fatty acid-binding protein (Ex-FABP) on immune and angiogenesis-related genes in chicken erythrocytes of tibial dyschondroplasia. | BMC genomics | BMC Genomics | 23 | 1 | 10.1186/s12864-022-08494-9 | eng | 2,022 | 4 | 22 | 2,022 | 4 | 22 | [BACKGROUND] Tibial dyschondroplasia (TD) is a bone disorder in which dead chondrocytes accumulate as a result of apoptosis and non-vascularization in the tibial bone of broiler chickens. The pathogenicity of TD is under extensive research but is yet not fully understood. Several studies have linked it to apoptosis and... | Angiogenesis; Biomarker-genes; Bone-deformity; Broiler; Ex-FABP; Immunity | 1.107 | 208 | Biotechnology; Genetics | Biochemistry, Genetics and Molecular Biology | 2,022 |
35,457,436 | Determinants of Late HIV Presentation at Ndlavela Health Center in Mozambique. | International journal of environmental research and public health | Int J Environ Res Public Health | 19 | 8 | 10.3390/ijerph19084568 | eng | 2,022 | 4 | 11 | 2,022 | 4 | 11 | [BACKGROUND] There has been tremendous progress in the fight against HIV worldwide; however, challenges persist in the control of HIV infection. These challenges include the high prevalence of late presenters. There are many disadvantages of late presentation-from reduced survival of the infected person to the risk of ... | HIV; Mozambique; determinants; late presentation | 0.828 | 229 | Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health | Environmental Science; Medicine | 2,022 |
35,475,131 | Impact of perioperative factors on nadir serum prostate-specific antigen levels after holmium laser enucleation of prostate. | BJUI compass | BJUI Compass | 2 | 3 | 10.1002/bco2.68 | eng | 2,021 | 5 | null | 2,021 | 1 | 5 | [OBJECTIVE] To investigate the relationship of preoperative prostate size, urinary retention, positive urine culture, and histopathological evidence of prostatitis or incidental prostate cancer on baseline and 3-month nadir prostate-specific antigen (PSA) value after Holmium laser enucleation of prostate (HoLEP). [PATI... | HoLEP; endoscopic enucleation for prostate; laser prostatectomy; prostate cancer screening; serum PSA; transurethral resection of prostate | null | 14 | Nephrology; Oncology; Surgery; Urology | Medicine | 2,021 |
35,485,627 | Comparison of the effectiveness of home visits and telephone follow-up on the self-efficacy of patients having un-dergone coronary artery bypass graft surgery (CABG) and the burden of their family caregivers: A randomized con-trolled trial. | Investigacion y educacion en enfermeria | Invest Educ Enferm | 40 | 1 | 10.17533/udea.iee.v40n1e14 | eng | 2,022 | 3 | null | null | null | null | [OBJECTIVES] This study aimed to compare home visits and telephone follow-up effectiveness on patients' self-efficacy undergoing Coro-nary Artery Bypass Graft Surgery -CABG- and caregivers' burden. [METHODS] In this randomized clinical trial, 114 patients undergoing CABG were assigned to the three groups of home visits... | caregivers; coronary artery bypass; house calls; self efficacy; self-management; telenursing | null | null | null | null | null |
35,519,929 | Comparison of Effect of Non-invasive Ventilation Delivered by Helmet vs Face Mask in Patients with COVID-19 Infection: A Randomized Control Study. | Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine | Indian J Crit Care Med | 26 | 3 | 10.5005/jp-journals-10071-24155 | eng | 2,022 | 3 | null | null | null | null | [BACKGROUND AND AIMS] We compared the effectiveness of non-invasive ventilation (NIV) provided by helmet mask vs face mask in patients with COVID-19. [METHODS AND MATERIALS] Between March and May 2021, a single-center, prospective, open-label randomized controlled research was undertaken. Sixty patients were randomly a... | COVID-19; Critical care unit; Face mask; Helmet continuous positive airway pressure; Hypoxia; Non-invasive ventilation | 0.439 | 45 | Critical Care and Intensive Care Medicine | Medicine | 2,022 |
35,518,787 | JPHYD Inhibits miR-21-5p/Smad7-Mediated Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells. | Journal of oncology | J Oncol | 2022 | null | 10.1155/2022/7823433 | eng | 2,022 | null | null | 2,022 | 4 | 26 | [BACKGROUND] Studies have shown that Jianpi Huayu Decoction (JPHYD) can inhibit the growth of hepatocellular carcinoma cells, but the mechanism of its effect was not clear at present. [METHODS] We assessed the effect of JPHYD using liver cancer cells as in vitro cell model and xenograft tumor as in vivo model. CCK8, Ed... | null | null | null | null | null | null |
35,518,517 | Acute Kidney Injury among Hospital-Admitted COVID-19 Patients: A Study from Jordan. | International journal of general medicine | Int J Gen Med | 15 | null | 10.2147/IJGM.S360834 | eng | 2,022 | null | null | 2,022 | 4 | 29 | [OBJECTIVE] During the COVID-19 pandemic, many patients have been admitted to hospitals with severe respiratory disease and suffered complications. Acute kidney injury (AKI) is among the more dangerous complications contributing to morbidity and mortality among patients. [METHODS] This retrospective study focused on al... | COVID; acute kidney injury; dialysis; mortality | null | null | null | null | null |
35,516,684 | Kangaroo mother care (KMC) for procedural pain in infants: A meta-analysis from the current evidence of randomized control trials and cross-over trials. | Journal of family medicine and primary care | J Family Med Prim Care | 11 | 4 | 10.4103/jfmpc.jfmpc_1383_21 | eng | 2,022 | 4 | null | 2,022 | 3 | 18 | [BACKGROUND] Kangaroo mother care (KMC), which is also known as Skin-to-skin (STS) care, is supposed to be effective in alleviating the pain of the neonates occurring during various procedures carried out in routine medical care or during the medical examination. [OBJECTIVES] The meta-analysis aimed to determine the ef... | Evidence-based medicine; Infant; Kangaroo-Mother Care method; Pain procedural; Skin-to-skin care | null | null | null | null | null |
35,514,053 | A novel deletion mutation accompanied by a point mutation in Lamin A/C gene: Screened from a dilated cardiomyopathy family. | Perfusion | Perfusion | 38 | 4 | 10.1177/02676591221090587 | eng | 2,023 | 5 | null | 2,022 | 5 | 5 | [BACKGROUND] There are 30%-40% of patients with dilated cardiomyopathy (DCM) having genetic causes, among which Lamin A and C gene (LMNA) mutation is the second most frequent DCM-related mutation, and Lamin A/C may be involved in the pathogenesis of DCM through the regulation of gene transcription or the direct effect ... | Lamin A/C; actin cardiopathy; dilated cardiomyopathy; family study; gene mutation | 0.433 | 55 | Advanced and Specialized Nursing; Safety Research; Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging | Medicine; Nursing; Social Sciences | 2,023 |
35,513,971 | Influences of protein levels on the cerebrospinal fluid distribution of ceftazidime & ceftriaxone in the cerebrospinal fluid of patients with inflamed meningitis. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy | J Infect Chemother | 28 | 8 | 10.1016/j.jiac.2022.04.021 | eng | 2,022 | 8 | null | 2,022 | 5 | 2 | [INTRODUCTION] Ceftazidime and ceftriaxone are used to treat various gram-negative pathogens, such as Streptococcus pneumoniae and Pseudomonas aeruginosa, and have shown excellent therapeutic efficacy against bacterial meningitis. However, there is insufficient information on the pharmacokinetic characteristics of thei... | Ceftazidime; Ceftriaxone; Cerebrospinal fluid; Intracerebrospinal distribution; Meningitis | 0.576 | 76 | Pharmacology; Infectious Diseases; Microbiology | Medicine | 2,022 |
35,513,935 | Treatment Outcome Measures for Spasmodic Dysphonia: A Systematic Review. | Journal of voice : official journal of the Voice Foundation | J Voice | 38 | 2 | 10.1016/j.jvoice.2021.10.001 | eng | 2,024 | 3 | null | 2,022 | 5 | 3 | [PURPOSE] This systematic review aims to identify instruments used to evaluate treatment outcomes for people with spasmodic dysphonia. [METHODS] Electronic database (PubMed, Cochrane Library, Embase, and CINAHL) searches and hand-searching identified studies that evaluated treatment approaches for spasmodic dysphonia w... | Laryngeal dystonia; Outcome measures; Spasmodic dysphonia; Systematic review; Treatment outcomes | 0.573 | 114 | LPN and LVN; Otorhinolaryngology; Speech and Hearing | Health Professions; Medicine; Nursing | 2,024 |
35,513,886 | Characteristics of the level of psychomotor abilities of female handball players. | BMC sports science, medicine & rehabilitation | BMC Sports Sci Med Rehabil | 14 | 1 | 10.1186/s13102-022-00475-5 | eng | 2,022 | 5 | 5 | 2,022 | 5 | 5 | [BACKGROUND] Handball is a high-intensity game, during which players run, change directions with or without the ball, interact with the opponent and make different decisions in both offensive and defensive actions. Players' performance may depend on a number of factors, including explosive force, power, speed and agili... | Body composition; Competition class; Movement time; Reaction time; Team sport; Women | null | null | null | null | null |
35,513,850 | A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets. | Genome medicine | Genome Med | 14 | 1 | 10.1186/s13073-022-01048-4 | eng | 2,022 | 5 | 6 | 2,022 | 5 | 6 | [BACKGROUND] Medical digital twins are computational disease models for drug discovery and treatment. Unresolved problems include how to organize and prioritize between disease-associated changes in digital twins, on cellulome- and genome-wide scales. We present a dynamic framework that can be used to model such change... | Inflammatory diseases; Multicellular network models; ScRNA-seq; Upstream regulators | 4.851 | 133 | Genetics; Genetics; Molecular Biology; Molecular Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,513,821 | Australian guideline on offloading treatment for foot ulcers: part of the 2021 Australian evidence-based guidelines for diabetes-related foot disease. | Journal of foot and ankle research | J Foot Ankle Res | 15 | 1 | 10.1186/s13047-022-00538-3 | eng | 2,022 | 5 | 5 | 2,022 | 5 | 5 | [BACKGROUND] Pressure offloading treatment is critical for healing diabetes-related foot ulcers (DFU). Yet the 2011 Australian DFU guidelines regarding offloading treatment are outdated. A national expert panel aimed to develop a new Australian guideline on offloading treatment for people with DFU by adapting internati... | Cast; Diabetes-related foot ulceration; Diabetic foot; Foot ulcer; Footwear; Guidelines; Offloading; Offloading device; Surgery; Treatment | 0.587 | 58 | Orthopedics and Sports Medicine | Medicine | 2,022 |
35,513,766 | Plantar flexion with inversion shows highest elastic modulus of calcaneofibular ligament using ultrasound share wave elastography. | Journal of ultrasound | J Ultrasound | 26 | 4 | 10.1007/s40477-022-00687-y | eng | 2,023 | 12 | null | 2,022 | 5 | 5 | [PURPOSE] The functional role of the calcaneofibular ligament (CFL) is still controversial. We aimed to investigate the anatomical features of the CFL on sonography and the elastic modulus of the CFL in different ankle positions using ultrasound shear-wave elastography (SWE). [METHODS] In 14 cadaveric ankles, the angle... | Anatomy; Ankle sprain; Calcaneofibular ligament; Share wave elastography; Ultrasound | 0.379 | 41 | Internal Medicine; Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,023 |
35,513,506 | Management of acute abdomen during the active disease course of COVID-19 and multisystem inflammatory syndrome in children. | Surgery today | Surg Today | 52 | 9 | 10.1007/s00595-022-02512-9 | eng | 2,022 | 9 | null | 2,022 | 5 | 5 | [PURPOSE] To evaluate the management of children with severe gastrointestinal symptoms during the disease course of COVID-19 and multisystem inflammatory syndrome (MIS-C). [METHODS] After ethical approval, we reviewed the medical records, retrospectively, of children with COVID-19 or MIS-C requiring surgical consultati... | Abdominal pain; COVID-19; Children; Gastrointestinal symptom; MIS-C; Pandemics | 0.753 | 77 | Surgery; Medicine | Medicine | 2,022 |
35,512,850 | Ex ante evaluation of the impact of tobacco control policy measures aimed at the point of sale in the Netherlands. | Tobacco control | Tob Control | 32 | 5 | 10.1136/tobaccocontrol-2021-057205 | eng | 2,023 | 9 | null | 2,022 | 5 | 5 | [INTRODUCTION] The Netherlands aims to implement stricter tobacco control policies targeting the retail environment. This paper is an ex ante policy evaluation of the potential impact of the current tobacco display and advertising ban as well as future tobacco sales bans on tobacco outlet visibility and availability. [... | advertising and promotion; environment; public policy | 1.654 | 147 | Health; Public Health, Environmental and Occupational Health | Medicine; Social Sciences | 2,023 |
35,512,624 | Change in nurses' psychosocial characteristics pre- and post-electronic medical record system implementation coinciding with the SARS-CoV-2 pandemic: pre- and post-cross-sectional surveys. | International journal of medical informatics | Int J Med Inform | 163 | null | 10.1016/j.ijmedinf.2022.104783 | eng | 2,022 | 7 | null | 2,022 | 4 | 29 | [BACKGROUND] The impacts of electronic medical record implementation on nurses, the largest healthcare workforce, have not been comprehensively examined. Negative impacts on nurses have implications for quality of patient care delivery and workforce retention. [OBJECTIVE] To investigate changes in nurses' well-being, i... | Burnout; Information technology; Nurses; Patient care; SARS-CoV-2; Well-being; Work engagement; Work satisfaction | 1.197 | 141 | Health Informatics | Medicine | 2,022 |
35,512,557 | Associations of maternal prenatal emotional symptoms with neurodevelopment of children and the neonatal meconium microbiota: A prospective cohort study. | Psychoneuroendocrinology | Psychoneuroendocrinology | 142 | null | 10.1016/j.psyneuen.2022.105787 | eng | 2,022 | 8 | null | 2,022 | 4 | 30 | [BACKGROUND] Maternal emotional symptoms during pregnancy increase the risk of neurodevelopmental problems in offspring, and microbiota have been shown to be a potential mechanism underlying the link. However, the associations among maternal prenatal emotional symptoms, the meconium microbiota, and offspring neurodevel... | Child neurodevelopment; Cohort study; Maternal emotional symptoms; Meconium microbiota | 1.391 | 210 | Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Psychiatry and Mental Health; Biological Psychiatry | Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience | 2,022 |
35,511,906 | Strategies for formula constant optimisation for intraocular lens power calculation. | PloS one | PLoS One | 17 | 5 | 10.1371/journal.pone.0267352 | eng | 2,022 | null | null | 2,022 | 5 | 5 | [BACKGROUND] To investigate modern nonlinear iterative strategies for formula constant optimisation and show the application and results from a large dataset using a set of disclosed theoretical-optical lens power calculation concepts. [METHODS] Nonlinear iterative optimisation algorithms were implemented for optimisin... | null | 0.885 | 467 | Multidisciplinary | Multidisciplinary | 2,022 |
35,511,253 | Automated Analysis of Drawing Process to Estimate Global Cognition in Older Adults: Preliminary International Validation on the US and Japan Data Sets. | JMIR formative research | JMIR Form Res | 6 | 5 | 10.2196/37014 | eng | 2,022 | 5 | 5 | 2,022 | 5 | 5 | [BACKGROUND] With the aging of populations worldwide, early detection of cognitive impairments has become a research and clinical priority, particularly to enable preventive intervention for dementia. Automated analysis of the drawing process has been studied as a promising means for lightweight, self-administered cogn... | behavior analysis; cognitive impairment; dementia; digital biomarkers; digital health; machine learning; motor control; multicohort; multination; tablet | 0.592 | 31 | Medicine; Health Informatics | Medicine | 2,022 |
35,511,194 | Clearance of Hepatitis B e Antigen in Untreated Chronic Hepatitis B Virus Infection: A Systematic Review and Meta-analysis. | The Journal of infectious diseases | J Infect Dis | 226 | 10 | 10.1093/infdis/jiac168 | eng | 2,022 | 11 | 11 | null | null | null | [BACKGROUND] In people with hepatitis B virus (HBV) infection, persistence of hepatitis B e antigen (HBeAg) is associated with clinical progression and need for treatment. HBeAg loss represents partial immune control and is a critical event in the natural history of chronic HBV. [METHODS] We conducted a systematic revi... | chronic hepatitis B infection; hepatitis B e antigen; hepatitis B e antigen clearance; natural history | 2.386 | 282 | Immunology and Allergy; Infectious Diseases | Medicine | 2,022 |
35,510,757 | Mentalization-oriented psychodynamic group therapy for patients with personality disorders: a naturalistic prospective cohort study. | Nordic journal of psychiatry | Nord J Psychiatry | 77 | 2 | 10.1080/08039488.2022.2067898 | eng | 2,023 | 2 | null | 2,022 | 5 | 5 | [OBJECTIVES] Patients with personality disorders (PDs) are often treated with non-manualized psychodynamic group therapy (PDT) lasting for several years. Non-manualized PDT often combines a variety of therapeutic approaches from different PDT traditions, including mentalization-based therapy. Currently, little is known... | Clinical practice; group therapy; mentalization; personality disorders; psychodynamic therapy | 0.741 | 69 | Psychiatry and Mental Health | Medicine | 2,023 |
35,510,491 | Effects of the coronavirus disease 2019 pandemic on subjective tinnitus perception. | The Journal of laryngology and otology | J Laryngol Otol | 136 | 5 | 10.1017/S0022215122000640 | eng | 2,022 | 5 | null | 2,022 | 3 | 2 | [OBJECTIVE] This study investigated the effects of the coronavirus disease 2019 pandemic on tinnitus severity and quality of life in individuals with subjective tinnitus. [METHODS] The study was carried out during the coronavirus disease 2019 pandemic. Sixty patients were evaluated with the Tinnitus Handicap Inventory ... | COVID-19; Pandemics; Quality Of Life; Tinnitus, Subjective; Visual Analog Scale | 0.57 | 79 | Medicine; Otorhinolaryngology | Medicine | 2,022 |
35,510,271 | Interim Analysis of STREAMLINE[®] Surgical System Clinical Outcomes in Eyes with Glaucoma. | Clinical ophthalmology (Auckland, N.Z.) | Clin Ophthalmol | 16 | null | 10.2147/OPTH.S358871 | eng | 2,022 | null | null | 2,022 | 4 | 27 | [PURPOSE] To characterize the clinical outcomes of a novel ab interno minimally invasive procedure with the STREAMLINE[®] Surgical System for creation of incisional goniotomies and canal of Schlemm viscodilation in eyes with mild to severe primary open-angle glaucoma (POAG). [METHODS] In a prospective, single-arm, firs... | MIGS; canal of Schlemm; glaucoma; goniotomy; trabecular meshwork; viscodilation | 0.76 | 84 | Ophthalmology | Medicine | 2,022 |
35,509,787 | Epstein-Barr virus-related diffuse large B-cell lymphoma type methotrexate-associated lymphoproliferative disorders presenting in the adrenal gland. | IJU case reports | IJU Case Rep | 5 | 3 | 10.1002/iju5.12429 | eng | 2,022 | 5 | null | 2,022 | 3 | 8 | [INTRODUCTION] Methotrexate-associated lymphoproliferative disorders appear during treatment with methotrexate as an immunosuppressive drug. However, the mechanism and frequency are still unknown, and the treatment is undefined. [CASE PRESENTATION] A 76-year-old woman was admitted to the hospital with back pain, and ma... | DLBCL; EBV; methotrexate; primary adrenal lymphoma | null | null | null | null | null |
35,509,786 | Complete response to pembrolizumab for metastatic urothelial carcinoma in the renal pelvis of allograft kidney. | IJU case reports | IJU Case Rep | 5 | 3 | 10.1002/iju5.12438 | eng | 2,022 | 5 | null | 2,022 | 3 | 25 | [INTRODUCTION] We present a case of urothelial carcinoma in a renal allograft successfully treated with pembrolizumab. [CASE PRESENTATION] A 39-year-old woman presented with nausea and anorexia 9 years after a renal transplantation. Positron emission tomography revealed a neoplasm of the renal pelvis of the allograft a... | immune checkpoint inhibitor; kidney transplantation; pembrolizumab; transplant rejection; urothelial carcinoma | null | null | null | null | null |
35,509,784 | Successful endoscopic treatment using thulium YAG laser for multiple ureteral fibroepithelial polyps in a pediatric patient. | IJU case reports | IJU Case Rep | 5 | 3 | 10.1002/iju5.12432 | eng | 2,022 | 5 | null | 2,022 | 3 | 17 | [INTRODUCTION] Ureteral fibroepithelial polyps are extremely rare and cause ureteropelvic junction obstruction in the pediatric population. Recent advancements in endoscopic treatment, such as holmium:yttrium-aluminum-garnet laser, have created more options for practitioners to treat multiple ureteral fibroepithelial p... | ablation; endoscopic management; multiple fibroepithelial polyps; pediatric; thulium:YAG laser | null | null | null | null | null |
35,509,704 | The association between frailty of older stroke patients during hospitalization and one-year all-cause mortality: A multicenter survey in China. | International journal of nursing sciences | Int J Nurs Sci | 9 | 2 | 10.1016/j.ijnss.2022.02.001 | eng | 2,022 | 4 | null | 2,022 | 2 | 20 | [OBJECTIVE] Frailty is a common geriatric syndrome defined as multiple deficits, impairing the capacity to figure out insult. Previous studies have reported a significant association between frailty and mortality in stroke patients. This study aimed to explore the association between frailty and mortality among older C... | Activities of daily living; Aged; China; Frailty; Stroke | 0.815 | 44 | Nursing | Nursing | 2,022 |
35,509,702 | Application of rational emotive behavior therapy in patients with colorectal cancer undergoing adjuvant chemotherapy. | International journal of nursing sciences | Int J Nurs Sci | 9 | 2 | 10.1016/j.ijnss.2022.02.002 | eng | 2,022 | 4 | null | 2,022 | 2 | 28 | [OBJECTIVE] This study aimed to explore the effects of our rational emotive behavior therapy (REBT) program on symptoms, anxiety, depression, and sleep state in patients with colorectal cancer (CRC) undergoing chemotherapy. [METHODS] From October 2020 to May 2021, fifty-six patients with CRC in a hospital in the Hunan ... | Adjuvant chemoradiotherapy; Anxiety; Colorectal neoplasms; Depression; Patients; Rational emotive behavior therapy | 0.815 | 44 | Nursing | Nursing | 2,022 |
35,509,536 | Intracranial ancient schwannoma originating from vestibular nerve: A case report and review of the literature. | Surgical neurology international | Surg Neurol Int | 13 | null | 10.25259/SNI_71_2022 | eng | 2,022 | null | null | 2,022 | 4 | 15 | [BACKGROUND] Ancient schwannoma (AS) is a subtype of schwannoma with degenerative features, which often progresses slowly over a long period of time. Intracranial AS is a rare benign tumor and there are no detailed reports of AS originating from the vestibular nerve. [CASE DESCRIPTION] Herein, we present the case of a ... | Cyst; Intracranial ancient schwannoma; Pathology; Vestibular schwannoma | 0.256 | 48 | Surgery; Neurology | Medicine | 2,022 |
35,509,486 | Factors influencing the degree of participation in surgical decision-making among Chinese patients with prostate cancer: A qualitative research. | Asian journal of urology | Asian J Urol | 9 | 2 | 10.1016/j.ajur.2021.08.003 | eng | 2,022 | 4 | null | 2,021 | 8 | 27 | [OBJECTIVE] There was increasingly demand of participation in surgical decision-making among Chinese patients with prostate cancer. However, due to the complex healthcare system and advanced care settings, it is quite challenging for the patients to gain sufficient support from the institute and the government. This re... | Decision-making; Influence factors; Participation; Prostate cancer; Qualitative research; Surgery | 0.623 | 31 | Urology | Medicine | 2,022 |
35,509,432 | Career Preferences among Nursing Students: A Cross-Sessional Study. | SAGE open nursing | SAGE Open Nurs | 8 | null | 10.1177/23779608221094538 | eng | 2,022 | null | null | 2,022 | 4 | 28 | [INTRODUCTION] It is estimated that mores nurses are needed in the future, nursing students' career preferences are important to contribute the shortage of nursing manpower in Macao. Little is known regarding the preferences for nursing students' career preferences and related factors among nursing students. [OBJECTIVE... | Macao; career preference; nursing students | 0.443 | 24 | Nursing | Nursing | 2,022 |
35,509,385 | Drug absorption in bariatric surgery patients: A narrative review. | Health science reports | Health Sci Rep | 5 | 3 | 10.1002/hsr2.605 | eng | 2,022 | 5 | null | 2,022 | 4 | 26 | [BACKGROUND] Despite the increase in the number of bariatric surgeries performed, little is known about the impact of the surgery on drug absorption. Unpredictability is assumed with drugs, given the anatomical changes after surgery. [OBJECTIVE] To evaluate the impact of bariatric surgery on drug absorption based on th... | bariatric surgery; drug absorption; drug use; pharmacotherapy; therapeutics | 0.543 | 26 | Medicine | Medicine | 2,022 |
35,509,282 | Multimodal imaging evaluation of occult macular dystrophy associated with a novel RP1L1 variant. | American journal of ophthalmology case reports | Am J Ophthalmol Case Rep | 26 | null | 10.1016/j.ajoc.2022.101550 | eng | 2,022 | 6 | null | 2,022 | 4 | 21 | [PURPOSE] Occult Macular Dystrophy (OMD) is an autosomal dominant inherited retinal dystrophy caused by mutations in the retinitis pigmentosa 1-like 1 (RP1L1) gene. The present study describes a novel RP1L1 variant, identified for the first time in two Italian sisters diagnosed with OMD, along with multimodal imaging f... | Macular dystrophy without fundus abnormalities; Miyake disease; Multimodal imaging; OCT Angiography; Occult macular dystrophy; RP1L1 | null | null | null | null | null |
35,509,266 | Histone demethylase KDM5A regulates the functions of human periodontal ligament stem cells during periodontitis via the miR-495-3p/HOXC8 axis. | Regenerative therapy | Regen Ther | 20 | null | 10.1016/j.reth.2021.12.002 | eng | 2,022 | 6 | null | 2,022 | 4 | 22 | [INTRODUCTION] Periodontitis is the sixth most common human disease and epigenetic regulation is identified to affect the functions of stem cells. This research aims to analyze the role of histone demethylase Lysine-specific demethylase 5A (KDM5A) in human periodontal ligament stem cells (hPDLSCs) with periodontitis. [... | Histone demethylase; KDM5A; Periodontitis; Stem cell function; hPDLSCs; miR-495-3p | 0.802 | 37 | Biomaterials; Biomedical Engineering; Developmental Biology | Biochemistry, Genetics and Molecular Biology; Engineering; Materials Science | 2,022 |
35,509,150 | In Silico Finite Element Analysis of Implant-Supported CAD-CAM Resin Composite Crowns. | Journal of prosthodontics : official journal of the American College of Prosthodontists | J Prosthodont | 32 | 3 | 10.1111/jopr.13531 | eng | 2,023 | 3 | null | 2,022 | 6 | 17 | [PURPOSE] The aim of this study was to evaluate the mechanical behavior of an implant-supported crown made using computer-aided design and computer-aided manufacturing (CAD-CAM) resin composite (RC) blocks in the posterior region. [MATERIAL AND METHODS] Four commercially available CAD-CAM RC blocks were used in this st... | CAD-CAM; dental implant; elastic modulus; finite element analysis; three-point bending test | 1.475 | 87 | Dentistry | Dentistry | 2,023 |
35,509,139 | What are the risk factors for acute otitis media treatment failure? | International journal of pediatric otorhinolaryngology | Int J Pediatr Otorhinolaryngol | 158 | null | 10.1016/j.ijporl.2022.111158 | eng | 2,022 | 7 | null | 2,022 | 4 | 27 | [OBJECTIVE] To identify risk factors associated with acute otitis media treatment failure (AOMTF) among 13-valent pneumococcal conjugate vaccine (PCV) immunized children. [METHODS] In this retrospective study, we identified children 12 years who were admitted to our hospital November 2017-October 2020. Children were ca... | Acute otitis media; Admission; Antibiotics; Failure; Guidelines; Treatment | 0.554 | 96 | Medicine; Otorhinolaryngology; Pediatrics, Perinatology and Child Health | Medicine | 2,022 |
35,509,094 | Disturbance of serum lipid metabolites and potential biomarkers in the Bleomycin model of pulmonary fibrosis in young mice. | BMC pulmonary medicine | BMC Pulm Med | 22 | 1 | 10.1186/s12890-022-01972-6 | eng | 2,022 | 5 | 4 | 2,022 | 5 | 4 | [BACKGROUND] Altered metabolic pathways have recently been considered as potential drivers of idiopathic pulmonary fibrosis (IPF) for the study of drug therapeutic targets. However, our understanding of the metabolite profile during IPF formation is lacking. [METHODS] To comprehensively characterize the metabolic disor... | Biomarkers; Metabolites; Mice; Pulmonary fibrosis | 0.999 | 85 | Pulmonary and Respiratory Medicine | Medicine | 2,022 |
35,509,051 | Air pollution, residential greenness, and metabolic dysfunction biomarkers: analyses in the Chinese Longitudinal Healthy Longevity Survey. | BMC public health | BMC Public Health | 22 | 1 | 10.1186/s12889-022-13126-8 | eng | 2,022 | 5 | 4 | 2,022 | 5 | 4 | [BACKGROUND] We hypothesize higher air pollution and fewer greenness exposures jointly contribute to metabolic syndrome (MetS), as mechanisms on cardiometabolic mortality. [METHODS] We studied the samples in the Chinese Longitudinal Healthy Longevity Survey. We included 1755 participants in 2012, among which 1073 were ... | Aging; Air pollution; Greenness; Interaction; Metabolic syndrome | 1.307 | 211 | Public Health, Environmental and Occupational Health | Medicine | 2,022 |
35,508,957 | Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4. | Clinical and molecular hepatology | Clin Mol Hepatol | 28 | 3 | 10.3350/cmh.2022.0039 | eng | 2,022 | 7 | null | 2,022 | 5 | 4 | [BACKGROUND/AIMS] Binge drinking leads to many disorders, including alcoholic hepatosteatosis, which is characterized by intrahepatic neutrophil infiltration and increases the risk of hepatocellular carcinoma (HCC). Molecular mechanisms may involve the migration of bacterial metabolites from the gut to the liver and th... | Alcoholics; Extracellular traps; Hepatocellular carcinoma; Hepatosteatosis; Lipopolysaccharides; Toll-like receptor 4 | 2.014 | 65 | Hepatology; Medicine; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
35,508,927 | Effects of Resistance Circuit Training on Health-Related Physical Fitness in People With Paraplegia: A Pilot Randomized Controlled Trial. | Annals of rehabilitation medicine | Ann Rehabil Med | 46 | 2 | 10.5535/arm.22012 | eng | 2,022 | 4 | null | 2,022 | 4 | 30 | [OBJECTIVE] To evaluate the efficacy and safety of 8 weeks of resistance circuit training in people with paraplegia due to spinal cord injury. [METHODS] Participants were randomized into experimental and control groups. Although the intensity and sequence of movements of the exercise programs were identical in both gro... | Circuit-based exercise; Paraplegia; Spinal cord injuries | 0.365 | 47 | Rehabilitation | Medicine | 2,022 |
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