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36,259,530
'Why should I feel guilty? I always give my best'. Guilt in Spanish women caring for dependent relatives from a gender perspective.
Aging & mental health
Aging Ment Health
27
9
10.1080/13607863.2022.2135681
eng
2,023
null
null
2,022
10
19
[OBJECTIVES] The sense of guilt in informal caregivers has been associated with lower levels of overall life-satisfaction, an increase in feelings of overwork, stress, and health problems, including anxiety and depression. Even though women who care for dependent relatives have higher levels of feelings of guilt than m...
Family caregiving; gender; guilt; health; thematic analysis; women
null
null
null
null
null
36,259,483
Spontaneous versus manual placental delivery during cesarean delivery: a systematic review and meta-analysis.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
J Matern Fetal Neonatal Med
35
26
10.1080/14767058.2022.2134769
eng
2,022
12
null
2,022
10
19
[OBJECTIVE] Standardized techniques have been established for cesarean delivery to reduce cesarean delivery complication rates. Current recommendations suggest against manual removal of the placenta. The purpose of the present meta-analysis is to evaluate published data and provide a summary of the evidence. [METHODS] ...
Cesarean delivery; blood transfusion; complications; hemorrhage; manual placental removal; meta-analysis
null
null
null
null
null
36,259,305
The Opinions and Practices of Saudi Arabian Dentists about Cervical Margin Relocation.
The journal of contemporary dental practice
J Contemp Dent Pract
23
6
null
eng
2,022
9
23
2,022
6
1
[AIM] The aim of this study was to assess the opinions and practices of different dentists about the cervical margin relocation (CMR) concept. [MATERIALS AND METHODS] A total of 432 general dentists, advanced general dentists (AGDs), periodontists, restorative dentists, and prosthodontists practicing in Saudi Arabia we...
Cervical margin relocation; Crown lengthening surgery
0.295
53
Dentistry
Dentistry
2,022
36,259,227
The association between caffeine and alcohol consumption and IVF/ICSI outcomes: A systematic review and dose-response meta-analysis.
Acta obstetricia et gynecologica Scandinavica
Acta Obstet Gynecol Scand
101
12
10.1111/aogs.14464
eng
2,022
12
null
2,022
10
19
[INTRODUCTION] The objective of this study was to evaluate the association between caffeine and alcohol consumption and in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) outcomes. [MATERIAL AND METHODS] The protocol was registered in the PROSPERO database on May 23, 2021 (registration number: CRD...
alcohol; assisted reproductive technology; caffeine; in vitro fertilization; intracytoplasmic sperm injection; meta-analysis
1.227
126
Medicine; Obstetrics and Gynecology
Medicine
2,022
36,258,189
Do coagulation or fibrinolysis reflect the disease condition in patients with soft tissue sarcoma?
BMC cancer
BMC Cancer
22
1
10.1186/s12885-022-10106-4
eng
2,022
10
18
2,022
10
18
[BACKGROUND] Coagulation and fibrinolysis are distinct processes that are highly correlated. Cells control coagulation and fibrinolysis by expression of tissue factor and urokinase-type plasminogen activator receptor on their surface. Tumor cells express these proteins, adjust their microenvironment and induce tumor ex...
And thrombin-antithrombin III complex; Coagulation; D-dimer; Fibrinolysis; Metastasis; Prognosis; Soft tissue sarcoma; Soluble fibrin
1.137
171
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,258,057
Prostate cancer induced bone pain: pathobiology, current treatments and pain responses from recent clinical trials.
Discover oncology
Discov Oncol
13
1
10.1007/s12672-022-00569-z
eng
2,022
10
18
2,022
10
18
[PURPOSE] Metastatic spread of prostate cancer to the skeleton may result in debilitating bone pain. In this review, we address mechanisms underpinning the pathobiology of metastatic prostate cancer induced bone pain (PCIBP) that include sensitization and sprouting of primary afferent sensory nerve fibres in bone. We a...
Analgesics; Central sensitization; Ectopic nerve fibre sprouting; Fentanyl; Morphine; NSAIDs; Opioids; Prostate cancer induced bone pain (PCIBP)
0.514
47
Endocrinology; Endocrinology, Diabetes and Metabolism; Oncology; Cancer Research; Endocrine and Autonomic Systems
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,022
36,256,662
Health care use and spending for Medicaid patients diagnosed with opioid use disorder receiving primary care in Federally Qualified Health Centers and other primary care settings.
PloS one
PLoS One
17
10
10.1371/journal.pone.0276066
eng
2,022
null
null
2,022
10
18
[INTRODUCTION] This nationwide study builds on prior research, which suggests that Federally Qualified Health Centers (FQHCs) and other primary care providers are associated with increased access to opioid use disorder (OUD) treatment. We compare health care utilization, spending, and quality for Medicaid patients diag...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,256,645
Analytical and clinical validation of a custom 15-gene next-generation sequencing panel for the evaluation of circulating tumor DNA mutations in patients with advanced non-small-cell lung cancer.
PloS one
PLoS One
17
10
10.1371/journal.pone.0276161
eng
2,022
null
null
2,022
10
18
[BACKGROUND] This is a pilot proof-of-concept study to evaluate the utility of a custom 15-gene circulating tumor DNA (ctDNA) panel as a potential companion molecular next-generation sequencing (NGS) assay for identifying somatic single nucleotide variants and indels in non-small-cell lung cancer (NSCLC) patients. The ...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,255,491
Skipping the cord during laparoscopic percutaneous internal ring suturing in children, is it reasonable?
Pediatric surgery international
Pediatr Surg Int
38
12
10.1007/s00383-022-05261-5
eng
2,022
12
null
2,022
10
18
[BACKGROUND] As a minimally invasive procedure, laparoscopic inguinal hernia repair in children was introduced. Percutaneous internal ring suturing (PIRS) is a popular technique. The main concern is that the spermatic cord will be trapped and/or the vasculature of the testes will be damaged in boys. This can be avoided...
Children; Inguinal hernia; Laparoscopy; Spermatic cord
0.575
78
Medicine; Pediatrics, Perinatology and Child Health; Surgery
Medicine
2,022
36,254,924
Management of bronchomalacia in infants post-cardiac surgery using synchronized nasal DuoPAP: A novel technology.
Annals of cardiac anaesthesia
Ann Card Anaesth
25
4
10.4103/aca.aca_112_21
eng
2,022
null
null
null
null
null
[BACKGROUND] Tracheo-bronchomalacia (TBM) is the weakness in the structural integrity of the cartilaginous ring and arch. It may occur in isolation with prematurity or secondarily in association with various congenital anomalies. Bronchomalacia is more commonly associated with congenital heart diseases. The conventiona...
Bronchomalacia; non-invasive ventilation; synchronized DuoPAP; tracheomalacia
null
null
null
null
null
36,254,805
Development of individual fitness score for conformity of prescriptions to the "Guidelines For Pharmacological Therapy of Schizophrenia".
Neuropsychopharmacology reports
Neuropsychopharmacol Rep
42
4
10.1002/npr2.12293
eng
2,022
12
null
2,022
10
18
[AIMS] The Guidelines for the Pharmacotherapy of Schizophrenia were established to improve the quality of medical care, and the EGUIDE project was conducted to train clinicians on guideline usage. A quality indicator (QI) was established to measure the prevalence of the guidelines, and a survey was conducted, which rev...
clinical practice guideline; individual fitness score (IFS); prescription; quality indicator; schizophrenia
0.651
24
Clinical Psychology; Pharmacology; Pharmacology; Psychiatry and Mental Health
Medicine; Pharmacology, Toxicology and Pharmaceutics; Psychology
2,022
36,254,747
A systematic review and meta-analysis of the evidence on inflammation in depressive illness and symptoms in chronic and end-stage kidney disease.
Psychological medicine
Psychol Med
53
12
10.1017/S0033291722003099
eng
2,023
9
null
2,022
10
18
[BACKGROUND] Depression affects approximately 27% of adults with chronic kidney disease (CKD) and end-stage kidney failure (ESKF). Depression in this population is associated with impaired quality of life and increased mortality. The extent of inflammation and the impact on depression in CKD/ESKF is yet to be establish...
Chronic kidney disease (CKD); cytokine; depression; depressive symptoms; end-stage kidney failure (ESKF); inflammation; inflammatory biomarkers; major depressive disorder; meta-analysis; systematic review
2.768
251
Applied Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,023
36,254,721
Association of Chronic Kidney Disease and Complications Following Acute Torsional Ankle Fracture.
Foot ankle international
Foot Ankle Int
43
12
10.1177/10711007221127026
eng
2,022
12
null
2,022
10
18
[BACKGROUND] Although chronic kidney disease (CKD) has been associated with poor outcomes following traumatic fractures, there is a scarcity of literature describing the effect on outcomes of ankle fractures. We will examine the impact of CKD on clinical outcomes following torsional ankle fracture, including complicati...
ankle fracture; chronic kidney disease; end-stage renal disease
null
null
null
null
null
36,254,535
Minimally Invasive Approaches Are Safe for Concomitant Mitral and Tricuspid Valve Surgery.
Innovations (Philadelphia, Pa.)
Innovations (Phila)
17
5
10.1177/15569845221128297
eng
2,022
9
null
2,022
10
18
[OBJECTIVE] The need for concomitant tricuspid surgery during mitral valve surgery is associated with higher operative risk. We hypothesized that concomitant tricuspid surgery through a minimally invasive thoracotomy (MICS) is associated with noninferior risk compared with a sternotomy. [METHODS] All patients undergoin...
minimally invasive; mitral; outcomes; tricuspid
0.168
14
Economics and Econometrics; Strategy and Management
Business, Management and Accounting; Economics, Econometrics and Finance
2,022
36,254,403
Small non-coding RNA sequencing reveals global dysregulation of piwi-interacting RNA (piRNA) expression in gonadal malignant germ cell tumours.
Andrology
Andrology
11
4
10.1111/andr.13312
eng
2,023
5
null
2,022
10
26
[BACKGROUND] Analyses of small non-coding RNA (ncRNA) expression in malignant germ cell tumours (GCTs) have focused on microRNAs (miRNAs). As GCTs all arise from primordial germ cells, and piwi-interacting RNAs (piRNAs) have important roles in maintaining germline integrity via transposon silencing, we hypothesised tha...
germ cell tumour; microRNA; ncRNA; piRNA; sequencing
1.002
76
Reproductive Medicine; Urology; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,254,179
Good clinical practice recommendations in allergen immunotherapy: Position paper of the Brazilian Association of Allergy and Immunology - ASBAI.
The World Allergy Organization journal
World Allergy Organ J
15
10
10.1016/j.waojou.2022.100697
eng
2,022
10
null
2,022
9
24
[BACKGROUND] Allergen Immunotherapy (AIT) represents one of the pillars in the treatment of allergic diseases. AIT is the only therapeutic strategy with curative potential, promoting the reduction of drug use and long-term symptom control even after the end of the treatment. The European Academy of Allergy, Asthma and ...
Clinical practice; HDM; House dust mite; SCIT; SLIT; Subcutaneous allergen immunotherapy; Sublingual allergen immunotherapy; VIT; Venom-specific immunotherapy
1.097
62
Pulmonary and Respiratory Medicine; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
36,254,097
Effects of different storage temperatures and time on frozen storage stability of steamed bread.
Journal of the science of food and agriculture
J Sci Food Agric
103
4
10.1002/jsfa.12277
eng
2,023
3
15
2,022
11
3
[BACKGROUNDS] This research intended to explore the effects of different frozen storage temperatures and time on the stability of steamed bread. The quality characteristics, moisture content and microstructure of steamed bread were determined after quick-frozen for 30 min at -32 °C and frozen storage at -6, -12, -18, -...
frozen storage; quality; steamed bread; temperature
null
null
null
null
null
36,254,050
PD-1 and CTLA-4 inhibitors in combination vs. alone for the treatment of advanced melanoma: A systematic review and meta-analysis.
Medicine
Medicine (Baltimore)
101
41
10.1097/MD.0000000000030561
eng
2,022
10
14
null
null
null
[BACKGROUND] Metastatic melanoma treatment has drastically changed during the past decade with the advent of immunotherapy. We conducted a meta-analysis, to assess PD-1 and CTLA-4 inhibitors in combination vs. alone for the treatment of advanced melanoma. [METHODS] The EMBASE, Medline via PubMed, Scopus, Cochrane Centr...
null
null
null
null
null
null
36,253,968
Associations of erythrocyte omega-3 fatty acids with cognition, brain imaging and biomarkers in the Alzheimer's disease neuroimaging initiative: cross-sectional and longitudinal retrospective analyses.
The American journal of clinical nutrition
Am J Clin Nutr
116
6
10.1093/ajcn/nqac236
eng
2,022
12
19
null
null
null
[BACKGROUND] The association between omega-3 (ω-3) PUFAs and cognition, brain imaging and biomarkers is still not fully established. [OBJECTIVES] The aim was to analyze the cross-sectional and retrospective longitudinal associations between erythrocyte ω-3 index and cognition, brain imaging, and biomarkers among older ...
Alzheimer disease; biomarkers; brain imaging; cognition; docosahexaenoic acid; eicosapentaenoic acid; mild cognitive impairment; omega-3
1.96
390
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
36,253,913
Subacute Posttraumatic Ascending Myelopathy: Case Report and Systematic Review of the Literature.
Clinical spine surgery
Clin Spine Surg
36
4
10.1097/BSD.0000000000001394
eng
2,023
5
1
2,022
10
18
[STUDY DESIGN] Case report and literature review. [OBJECTION] Aim of this study was to summarize the current evidence base behind subacute posttraumatic ascending myelopathy (SPAM) including the epidemiology, presentation, diagnosis, prognosis, and etiology. [SUMMARY OF BACKGROUND DATA] SPAM is a rare, potentially fata...
null
0.834
45
Orthopedics and Sports Medicine; Surgery; Neurology
Medicine
2,023
36,253,836
Prevalence, antimicrobial resistance, virulence gene profile and molecular typing of Campylobacter species isolated from poultry meat samples.
Veterinary medicine and science
Vet Med Sci
8
6
10.1002/vms3.944
eng
2,022
11
null
2,022
10
17
[BACKGROUND] Campylobacter jejuni and Campylobacter coli are the most significant Campylobacter species responsible for severe gastrointestinal disorders. Raw poultry meat is considered a source of Campylobacter transmission to the human population. [OBJECTIVES] The present study was aimed to assess the prevalence rate...
Campylobacter coli; Campylobacter jejuni; antimicrobial resistance; molecular typing; raw poultry meat; virulence factors
0.451
30
Veterinary
Veterinary
2,022
36,253,832
Breastfeeding by a mother taking cyclosporine for nephrotic syndrome.
International breastfeeding journal
Int Breastfeed J
17
1
10.1186/s13006-022-00514-4
eng
2,022
10
17
2,022
10
17
[BACKGROUND] Cyclosporine is widely used for immunosuppressive treatment of various systematic and local autoimmune diseases. Breastfeeding is conventionally contraindicated when treating with cyclosporine due to its excretion into breast milk, which may cause immune suppression of exposed infants and affect infants` g...
Breastfeeding; Cyclosporine; Nephrotic syndrome
0.99
60
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,022
36,253,804
Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine-resistant treatment-refractory schizophrenia: a 12-week randomized, double-blind, placebo-controlled trial.
Military Medical Research
Mil Med Res
9
1
10.1186/s40779-022-00420-0
eng
2,022
10
18
2,022
10
18
[BACKGROUND] Although clozapine is an effective option for treatment-resistant schizophrenia (TRS), there are still 1/3 to 1/2 of TRS patients who do not respond to clozapine. The main purpose of this randomized, double-blind, placebo-controlled trial was to explore the amisulpride augmentation efficacy on the psychopa...
Amisulpride; Augmentation; Clozapine; Schizophrenia
2.042
53
Medicine
Medicine
2,022
36,253,802
The association between dietary glycemic index and cardio-metabolic risk factors in obese individuals.
BMC nutrition
BMC Nutr
8
1
10.1186/s40795-022-00608-6
eng
2,022
10
17
2,022
10
17
[BACKGROUND] The dietary glycemic index (GI) has been introduced as a novel index to elucidate the potential of foods to increase postprandial glucose. According to the limited available data about the association of GI with cardio-metabolic risk factors such as lipid profile, blood glucose markers, and blood pressure ...
Fatty acid desaturase 2; Glycemic index; Metabolic parameters; Obesity
0.528
36
Medicine; Public Health, Environmental and Occupational Health; Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Medicine; Nursing
2,022
36,253,800
A novel chromatin regulator-related immune checkpoint related gene prognostic signature and potential candidate drugs for endometrial cancer patients.
Hereditas
Hereditas
159
1
10.1186/s41065-022-00253-w
eng
2,022
10
18
2,022
10
18
[BACKGROUND] Endometrial cancer (EC) is the most common gynecologic malignancy in developed countries and its prevalence is increasing. As an emerging therapy with a promising efficacy, immunotherapy has been extensively applied in the treatment of solid tumors. In addition, chromatin regulators (CRs), as essential ups...
Chromatin regulators; Endometrial cancer; Immune checkpoints; Prognosis; TCGA
0.565
57
Medicine; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,253,718
Time optimization of gadobutrol-enhanced brain MRI for metastases and primary tumors using a dynamic contrast-enhanced imaging.
BMC medical imaging
BMC Med Imaging
22
1
10.1186/s12880-022-00909-z
eng
2,022
10
17
2,022
10
17
[BACKGROUND] Recent advances in rapid imaging techniques necessitate the reconsideration of the optimal imaging delay time for contrast-enhanced T1-weighted imaging. The aim of our study was to determine the optimal contrast-enhanced T1-weighted imaging delay time from the obtained time-signal intensity curve (TIC) usi...
Contrast agent; Gadobutrol; Intracerebral metastases; MRI; Primary brain tumor
0.535
56
Radiology, Nuclear Medicine and Imaging
Medicine
2,022
36,253,342
Regulator of telomere elongation helicase 1 gene and its association with malignancy.
Cancer reports (Hoboken, N.J.)
Cancer Rep (Hoboken)
6
1
10.1002/cnr2.1735
eng
2,023
1
null
2,022
10
17
[BACKGROUND] With the progression of next-generation sequencing technologies, researchers have identified numerous variants of the regulator of telomere elongation helicase 1 (RTEL1) gene that are associated with a broad spectrum of phenotypic manifestations, including malignancies. At the molecular level, RTEL1 is inv...
G-quadruplex; RTEL1; dyskeratosis congenita; glioma; malignancy; telomere length
0.571
24
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,253,253
Prospective study of adoptive activated αβT lymphocyte immunotherapy for refractory cancers: development and validation of a response scoring system.
Cytotherapy
Cytotherapy
25
1
10.1016/j.jcyt.2022.09.007
eng
2,023
1
null
2,022
10
14
[BACKGROUND AIMS] This prospective clinical study aimed to determine the efficacy and prognostic factors of adoptive activated αβT lymphocyte immunotherapy for various refractory cancers. The primary endpoint was overall survival (OS), and the secondary endpoint was radiological response. [METHODS] The authors treated ...
cellular immunotherapy; prognosis; refractory cancers; scoring system
1.084
109
Transplantation; Cancer Research; Cell Biology; Genetics; Immunology; Immunology and Allergy; Oncology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,023
36,253,097
Neighbourhood natural space and the narrowing of socioeconomic inequality in years of life lost: a cross-sectional ecological analysis of the Scottish Burden of Disease.
Journal of epidemiology and community health
J Epidemiol Community Health
76
12
10.1136/jech-2022-219111
eng
2,022
12
null
2,022
10
17
[BACKGROUND] Natural space is associated with reduced risk of, and narrower socioeconomic inequalities in, diseases that affect older populations, and some contributors to premature mortality in younger individuals. Burden of disease measures such as years of life lost (YLL) are influenced by premature poor health and ...
geography; health inequalities; spatial analysis
2.105
199
Epidemiology; Public Health, Environmental and Occupational Health
Medicine
2,022
36,252,741
Causal analyses with target trial emulation for real-world evidence removed large self-inflicted biases: systematic bias assessment of ovarian cancer treatment effectiveness.
Journal of clinical epidemiology
J Clin Epidemiol
152
null
10.1016/j.jclinepi.2022.10.005
eng
2,022
12
null
2,022
10
15
[BACKGROUND AND OBJECTIVES] Drawing causal conclusions from real-world data (RWD) poses methodological challenges and risk of bias. We aimed to systematically assess the type and impact of potential biases that may occur when analyzing RWD using the case of progressive ovarian cancer. [METHODS] We retrospectively compa...
Causal inference; Comparative effectiveness; Electronic health records; Inverse probability weighting; Longitudinal data; Target trial
3.362
262
Epidemiology
Medicine
2,022
36,252,555
Reduced coupling between the global blood-oxygen-level-dependent signal and cerebrospinal fluid inflow is associated with the severity of small vessel disease.
NeuroImage. Clinical
Neuroimage Clin
36
null
10.1016/j.nicl.2022.103229
eng
2,022
null
null
2,022
10
12
[BACKGROUND] Small vessel disease (SVD) is highly prevalent in the elderly and associated with an increased risk of dementia and stroke. SVD may have disturbed cerebrospinal fluid (CSF) flow, which can compromise waste clearance and accelerate disease progression. [METHODS] We retrospectively included 146 SVD patients ...
CSF dynamics; Cerebral small vessel disease; Perivascular space; gBOLD-CSF coupling
null
null
null
null
null
36,252,468
Purification and characterization of enolase as a novel allergen in Platanus acerifolia pollen.
International immunopharmacology
Int Immunopharmacol
113
Pt A
10.1016/j.intimp.2022.109313
eng
2,022
12
null
2,022
10
14
[BACKGROUND] The pollen from Platanus acerifolia (P. acerifolia) is one of the main causes of allergic disorders. To date, only 4 allergens have been identified from this pollen. But previous studies showed that there still exist under-recognized allergens in it. The aim of this study was to comprehensively investigate...
Allergen; Enolase; Molecular modeling; Platanus acerifolia; Pollen
1.1
155
Pharmacology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,252,245
Effectiveness of Opioid Analgesic Medicines Prescribed in or at Discharge From Emergency Departments for Musculoskeletal Pain : A Systematic Review and Meta-analysis.
Annals of internal medicine
Ann Intern Med
175
11
10.7326/M22-2162
eng
2,022
11
null
2,022
10
18
[BACKGROUND] The comparative benefits and harms of opioids for musculoskeletal pain in the emergency department (ED) are uncertain. [PURPOSE] To evaluate the comparative effectiveness and harms of opioids for musculoskeletal pain in the ED setting. [DATA SOURCES] Electronic databases and registries from inception to 7 ...
null
3.845
445
Internal Medicine; Medicine
Medicine
2,022
36,252,207
Reliability and Minimal Detectable Change of the Standardized Assessment of Reaction Time.
Journal of athletic training
J Athl Train
58
6
10.4085/1062-6050-0391.22
eng
2,023
6
1
null
null
null
[CONTEXT] Postconcussion reaction time deficits are common, but existing assessments lack sport-related applicability. We developed the Standardized Assessment of Reaction Time (StART) tool to emulate the simultaneous cognitive and motor function demands in sport, but its reliability is unestablished. [OBJECTIVES] To d...
mild traumatic brain injury; response time; return to play; visuomotor function
1.141
139
Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,023
36,251,950
A novel variant in the HX repeat motif of ATN1 in a Chinese patient with CHEDDA syndrome and literature review.
Molecular genetics genomic medicine
Mol Genet Genomic Med
10
12
10.1002/mgg3.2068
eng
2,022
12
null
2,022
10
17
[BACKGROUND] CHEDDA syndrome is a rare neurodevelopmental syndrome caused by heterozygous missense or indel variants in the HX repeat motif of ATN1 gene. To date, CHEDDA has been identified in a few ethnic groups, and only 17 patients have been reported in literature, and no case has been reported in any country or reg...
ATN1; CHEDDA; HX repeat motif; developmental delay
null
null
null
null
null
36,251,604
Transmetatarsal Amputations: Outcomes of Primary Healing versus Secondary Healing.
Journal of the American Podiatric Medical Association
J Am Podiatr Med Assoc
112
5
10.7547/21-173
eng
2,022
null
null
null
null
null
[BACKGROUND] Transmetatarsal amputations are limb salvage surgical procedures that preserve limb length and functional ankle joints. Indications for transmetatarsal amputations include forefoot trauma, infection, and ischemia. Prior research demonstrates patients who undergo transmetatarsal amputations have a lower 2-y...
null
0.202
67
Medicine; Orthopedics and Sports Medicine; Podiatry
Health Professions; Medicine
2,022
36,251,387
A "Step-Ramp-Step" Protocol to Identify Running Speed and Power Associated with the Maximal Metabolic Steady State.
Medicine and science in sports and exercise
Med Sci Sports Exerc
55
3
10.1249/MSS.0000000000003066
eng
2,023
3
1
2,022
10
17
[PURPOSE] A previously established Step-Ramp-Step (SRS) exercise protocol was able to accurately predict the work rate associated with the maximal metabolic steady state (MMSS) in cyclists. The purpose of this study was to determine whether a modified SRS protocol could predict the running speed and power associated wi...
null
1.47
271
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,023
36,251,288
Association Between Angiotensin Receptor Blocker Therapy and Incidence of Epilepsy in Patients With Hypertension.
JAMA neurology
JAMA Neurol
79
12
10.1001/jamaneurol.2022.3413
eng
2,022
12
1
null
null
null
[IMPORTANCE] Arterial hypertension is associated with an increased incidence of epilepsy. Results from animal studies suggest that angiotensin receptor blocker (ARB) therapy could inhibit epileptic seizures. However, there is a lack of clinical data to support the use of ARB therapy in humans. [OBJECTIVE] To assess whe...
null
null
null
null
null
null
36,251,237
Young adults in motor vehicle collisions in Norway: user safety errors observed in majority of cases with severe or fatal injuries.
Forensic science, medicine, and pathology
Forensic Sci Med Pathol
18
4
10.1007/s12024-022-00541-x
eng
2,022
12
null
2,022
10
17
[PURPOSE] We performed a multidisciplinary investigation of young adults involved in motor vehicle collisions (MVCs) to elucidate injury mechanisms and the role of passive safety equipment such as seat belts and airbags. [METHODS] MVCs resulting in death or serious injuries to the driver or passengers aged 16-24 years ...
Collision investigation; Injury mechanism; Motor vehicle collision; Safety errors; Young adults
0.473
50
Pathology and Forensic Medicine; Medicine
Medicine
2,022
36,250,922
Application value of contrast-enhanced ultrasound in preoperative localization of microwave ablation for primary hyperparathyroidism.
Journal of applied clinical medical physics
J Appl Clin Med Phys
23
12
10.1002/acm2.13802
eng
2,022
12
null
2,022
10
17
[BACKGROUND] Ultrasonography (US) and [99m] Technetium-sestamibi scintigraphy ([99m] Tc-MIBI) are currently first-line imaging modalities to localize parathyroid adenomas with sensitivities of 80% and 84%, respectively. Therefore, finding other modalities to further improve the diagnostic accuracy for preoperative loca...
99mTechnetium-sestamibi; hyperparathyroidism; parathyroid neoplasms; ultrasonography
0.629
64
Radiation; Instrumentation; Medicine; Radiology, Nuclear Medicine and Imaging
Medicine; Physics and Astronomy
2,022
36,250,768
Understanding adolescent girls' and young women's health-seeking for female genital cosmetic surgery: How can clinicians help their patients?
Journal of paediatrics and child health
J Paediatr Child Health
59
1
10.1111/jpc.16248
eng
2,023
1
null
2,022
10
17
[AIM] This study aimed to understand why adolescent girls and young women (AGYW) would seek consultation with a health professional about genital appearance concerns and/or request female genital cosmetic surgery (FGCS). The information derived from these participant interviews can inform clinical practice and help cli...
plastic; surgery; surgeryadolescent; urology/gynaecology
0.499
90
Pediatrics, Perinatology and Child Health
Medicine
2,023
36,250,247
Anti-Inflammatory and Chondro-Protective Effects of Acidic Polysaccharide from Enteromorpha Prolifera in Experimental Models of Osteoarthritis In-Vitro and In-Vivo.
Cartilage
Cartilage
13
4
10.1177/19476035221129573
eng
2,022
12
null
2,022
10
17
[OBJECTIVE] Osteoarthritis (OA) progression has been shown to increase the expression of inflammatory cytokines in joints, leading to the destruction of cartilage matrix. Interleukin (IL)-1β is a potent inflammatory cytokine associated with osteoarthritic synovial fluid. The protective effects of polysaccharides from E...
chondrocyte; enteromorpha prolifera; osteoarthritis; oxidative stress
0.687
52
Physical Therapy, Sports Therapy and Rehabilitation; Biomedical Engineering; Immunology and Allergy
Engineering; Health Professions; Medicine
2,022
36,250,079
Effect of fetoscopic laser surgery on the placental characteristics and birth-weight discordance of twins with twin-to-twin transfusion syndrome.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.942816
eng
2,022
null
null
2,022
9
29
[OBJECTIVE] This study explored the effect of fetoscopic laser surgery on the placental structure and birth-weight discordance of twin-to-twin transfusion syndrome (TTTS). [METHODS] A retrospective cohort study was conducted in TTTS patients who were admitted to the Peking University Third Hospital between April 2014 a...
anastomoses; birth-weight; fetoscopic laser surgery; placental territory; twin-to-twin transfusion syndrome
0.926
102
Medicine
Medicine
2,022
36,250,029
Responsiveness of the Post-Concussion Symptom Scale to Monitor Clinical Recovery After Concussion or Mild Traumatic Brain Injury.
Orthopaedic journal of sports medicine
Orthop J Sports Med
10
10
10.1177/23259671221127049
eng
2,022
10
null
2,022
10
12
[BACKGROUND] The Post-Concussion Symptom Scale (PCSS) is used to assess the number and intensity of symptoms after a concussion/mild traumatic brain injury. However, its responsiveness to monitor clinical recovery has yet to be determined. [PURPOSE] To evaluate the responsiveness of the PCSS to change and longitudinal ...
Post-Concussion Symptoms Scale; concussion; persistent postconcussive symptoms; responsiveness
1.113
68
Orthopedics and Sports Medicine
Medicine
2,022
36,249,477
Design, implementation, and evaluation of an innovative intelligence information management system for premature infants.
Digital health
Digit Health
8
null
10.1177/20552076221127776
eng
2,022
null
null
2,022
10
11
[INTRODUCTION] Low birth weight is the most important condition of neonatal community health and the main cause of neonates' mortality. Identifying the indexes associated with this condition, and factors to prevent, and managing related data can help reduce the birth of premature infants to reduce the mortality rate du...
Premature infant; health information management; neonatal registry; premature birth system; prematurity; system evaluation
0.989
39
Computer Science Applications; Health Policy; Health Informatics; Health Information Management
Computer Science; Health Professions; Medicine
2,022
36,249,089
The impact of COVID-19 on presentation and diagnosis of head and neck squamous cell carcinoma.
Laryngoscope investigative otolaryngology
Laryngoscope Investig Otolaryngol
7
5
10.1002/lio2.893
eng
2,022
8
12
2,022
8
12
[OBJECTIVE] To analyze how the COVID-19 pandemic has influenced trends in head and neck squamous cell carcinoma (HNSCC) presentation and diagnosis-including referral patterns, stage at presentation, and time to diagnosis-over a longitudinal time course. [SETTING] Multicenter tertiary care academic institution. [METHODS...
head and neck cancer; presentation setting
0.701
42
Otorhinolaryngology; Surgery
Medicine
2,022
36,249,024
Obesity may not be related to pathologic response in locally advanced rectal cancer following neoadjuvant chemoradiotherapy.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.994444
eng
2,022
null
null
2,022
9
29
[BACKGROUND] The aim of this study is to evaluate the correlation between body mass index (BMI) and body fat composition (measured with radiological fat parameters (RFP)) and pathological response after neoadjuvant chemoradiotherapy for locally advanced rectal cancer patients. The secondary aim of the study was to asse...
BMI; neoadjuvant chemoradiotherapy; obesity; pathological response; visceral fat
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,248,977
Impact of adjuvant radiation therapy after definitive surgery in senior adults 80 years old with advanced head and neck squamous cell carcinoma on overall survival.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.973245
eng
2,022
null
null
2,022
9
30
[BACKGROUND] Adjuvant radiotherapy (RT) following surgical resection confers a survival benefit for adult patients with locally advanced head and neck squamous cell carcinoma (HNSCC). We aim to investigate if adjuvant RT provides a similar survival advantage to patients ages 80+ through a national curated database. [ME...
National Cancer Database; adjuvant radiotherapy; head and neck cancer; senior adult; survival
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,248,957
Extended endoscopic endonasal approach for resecting anterior intrinsic third ventricular craniopharyngioma.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.998683
eng
2,022
null
null
2,022
9
29
[BACKGROUND] The surgical treatment of the extended endoscopic endonasal approach (EEEA) is a safe and effective treatment for suprasellar craniopharyngiomas. However, due to damage to the hypothalamus and third ventricle floor (TVF), EEEA is generally regarded as unsuitable in treating intrinsic third ventricle cranio...
extended endoscopic endonasal approach; in situ bone flap; intrinsic third ventricular craniopharyngioma; skull base reconstruction; translamina terminalis
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,248,434
LncRNA-PAX8-AS1 Silencing Decreases Cell Viability, Enhances Apoptosis, and Suppresses Doxorubicin Resistance in Myeloid Leukemia via the miR-378g/ERBB2 Axis.
Evidence-based complementary and alternative medicine : eCAM
Evid Based Complement Alternat Med
2022
null
10.1155/2022/2295044
eng
2,022
null
null
2,022
10
6
[OBJECTIVE] Considering the role of lncRNAs reported as regulators in acute myeloid leukemia (AML) progression, the current research aims to investigate the role of PAX8-AS1 in chemo-resistant AML. [METHODS] Human AML cells HL60 and human doxorubicin (ADM)-resistant AML cells (HL60/ADM cells) were used to establish in ...
null
null
null
null
null
null
36,247,899
Patient-Reported Symptoms in the Global Multiple System Atrophy Registry.
Movement disorders clinical practice
Mov Disord Clin Pract
9
7
10.1002/mdc3.13544
eng
2,022
10
null
2,022
8
29
[BACKGROUND] The Global Multiple System Atrophy Registry (GLOMSAR) was established in 2013. It is an online patient-reported contact registry open and free that relies on self-reported diagnosis by the patient or caregiver. [OBJECTIVES] To report the demographics of patients enrolled in GLOMSAR and the results of an an...
burden; multiple system atrophy; patient advocacy groups; patient registries; synucleinopathies
0.632
42
Neurology; Neurology
Medicine; Neuroscience
2,022
36,247,855
Systematic Review of the Efficacy and Safety of Traditional Chinese Medicine Granules Associated with Hormone When Treating Primary Nephrotic Syndrome in Children.
Contrast media molecular imaging
Contrast Media Mol Imaging
2022
null
10.1155/2022/2520367
eng
2,022
null
null
2,022
9
27
[OBJECTIVE] To systematically evaluate the efficacy and safety of traditional Chinese medicine (TCM) granules associated with hormones when treating primary nephrotic syndrome (PNS) in children. [METHODS] Search online databases such as PubMed, EMBASE, ScienceDirect, Cochrane Library, China Knowledge Network Database (...
null
null
null
null
null
null
36,247,772
Risk factors for repeated recurrence of cerebral aneurysms treated with endovascular embolization.
Frontiers in neurology
Front Neurol
13
null
10.3389/fneur.2022.938333
eng
2,022
null
null
2,022
9
29
[PURPOSE] To explore the risk factors of recurrence after second endovascular embolization of recurrent aneurysms and the characteristics of recurrent refractory aneurysms to help clinical decision-making. [MATERIALS AND METHODS] Forty-nine patients with recurrent aneurysms who underwent repeated embolization were retr...
embolization; refractory; risk factors; saccular aneurysms; second recurrence
0.978
118
Neurology; Neurology
Medicine; Neuroscience
2,022
36,247,479
The impact of UEFA Euro 2020 football championship on Takotsubo Syndrome: Results of a multicenter national registry.
Frontiers in cardiovascular medicine
Front Cardiovasc Med
9
null
10.3389/fcvm.2022.951882
eng
2,022
null
null
2,022
9
28
[OBJECTIVES] The UEFA 2020 European Football Championship held in multiple cities across Europe from June 11 to July 11, 2021, was won by Italy, providing an opportunity to examine the relationship between emotional stress and the incidence of acute cardiovascular events (ACE). [METHODS AND RESULTS] Cardiovascular hosp...
ACS; Takotsubo; angina pectoris; cardiomyopathies; cardiovascular disease
1.391
81
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,247,349
The impact of COVID-19 on police officer activities.
Journal of criminal justice
J Crim Justice
82
null
10.1016/j.jcrimjus.2022.101943
eng
2,022
null
null
2,022
5
31
[OBJECTIVE] This study examined the impact of COVID-19 on police reactive and proactive activities in Houston, Texas. Seven types of police officer reactivity and three distinct categories of proactivity were examined. [METHODS] Weekly calls for service data from January 1, 2018-December 31, 2020 were analyzed through ...
COVID-19; Calls for service; Interrupted time series; Proactivity; Routine activities
null
null
null
null
null
36,247,201
Study on the Association Between Dietary Habits, Patterns and Frailty of the Elderly: A Cross-Sectional Survey from Communities in China.
Clinical interventions in aging
Clin Interv Aging
17
null
10.2147/CIA.S378138
eng
2,022
null
null
2,022
10
13
[OBJECTIVE] The purpose of this study was to explore the effects of Chinese dietary habits and patterns on frailty among elderly people in Xi'an the community. We also sought to provide dietary suggestions for prevention of frailty. [METHODS] A cross-sectional survey was conducted and participants were divided into thr...
dietary pattern; elderly; frailty; nutrients; protein
0.923
114
Medicine; Geriatrics and Gerontology
Medicine
2,022
36,247,188
Diet Quality Indices in Relation to Cardiovascular Risk Factors in T2DM Patients: A Systematic Review.
International journal of preventive medicine
Int J Prev Med
13
null
10.4103/ijpvm.IJPVM_494_20
eng
2,022
null
null
2,022
8
8
[BACKGROUND] Dietary quality indices are practical as an instrument to investigate the extent of adhering to a special diet to prevent cardiovascular disease (CVD) in type 2 diabetes mellitus (T2DM). Considering the lack of any systematic review with regards to this issue, our aim was to examine observational studies t...
Cardiovascular diseases; diabetes mellitus; diet; food quality.
0.472
60
Public Health, Environmental and Occupational Health
Medicine
2,022
36,246,774
Socioeconomic factors and bleeding events in patients with incident atrial fibrillation: A Finnish nationwide cohort study.
International journal of cardiology. Heart vasculature
Int J Cardiol Heart Vasc
43
null
10.1016/j.ijcha.2022.101131
eng
2,022
12
null
2,022
10
10
[BACKGROUND] Low socioeconomic status has been associated with higher risk of ischemic stroke and death in patients with atrial fibrillation (AF). However, whether socioeconomic status affects risk of bleeding events is unknown. We assessed the hypothesis that low income and educational attainment are associated with h...
Adverse outcomes; Atrial fibrillation; Bleeding risk; Income, educational attainment; Socioeconomic status
null
null
null
null
null
36,246,568
Analysis of Adrenocorticotropic Hormone and Cortisol Levels in Acute Respiratory Distress Syndrome COVID-19 Patients.
Disease markers
Dis Markers
2022
null
10.1155/2022/3191285
eng
2,022
null
null
2,022
9
30
[OBJECTIVE] SARS-CoV-2 infection may cause multiple organ failure. However, scarce information can be found on the impact on the endocrine system. This study was conducted to determine plasma Adrenocorticotropic hormone (ACTH) and plasma cortisol levels in a cohort of COVID-19 patients with Acute Respiratory Distress S...
null
0.662
85
Biochemistry; Clinical Biochemistry; Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,245,628
Sutureless aortic valve replacement in high-risk patients with active infective endocarditis.
Journal of thoracic disease
J Thorac Dis
14
9
10.21037/jtd-22-486
eng
2,022
9
null
null
null
null
[BACKGROUND] Surgical aortic valve replacement remains the gold standard of treatment in patients with active infective endocarditis. Such procedures tend to carry a significantly higher operative risk when compared to the conventional aortic valve replacement for a non-infective aortic valve disease. Sutureless aortic...
Infective endocarditis; Perceval; sutureless aortic valve replacement (SU-AVR)
0.646
95
Pulmonary and Respiratory Medicine
Medicine
2,022
36,245,623
Anatomical segmentectomy under uniportal video-assisted thoracoscopic surgery for early staged non-small cell lung cancer: a case report.
Journal of thoracic disease
J Thorac Dis
14
9
10.21037/jtd-21-1624
eng
2,022
9
null
null
null
null
[BACKGROUND] Anatomical segmentectomy has become more and more universal in thoracic surgery because of the increasing detection of pulmonary nodules with ground-glass opacity (GGO), most of which proved early staged non-small cell lung cancer (NSCLC) postoperative. With the advantage of preservation of normal lung tis...
null
0.646
95
Pulmonary and Respiratory Medicine
Medicine
2,022
36,245,604
Development and clinical application of an electronic health record quality control system for pulmonary aspergillosis based on guidelines and natural language processing technology.
Journal of thoracic disease
J Thorac Dis
14
9
10.21037/jtd-22-532
eng
2,022
9
null
null
null
null
[BACKGROUND] There are considerable differences in the diagnosis and treatment of pulmonary aspergillosis (PA) between specialized hospitals and primary hospitals or developed areas and underdeveloped areas in China. There is a lack of electronic systems that assist respiratory physicians in standardizing the diagnosis...
Electronic health records (EHR); guideline-based quality control system; natural language processing (NLP); pulmonary aspergillosis (PA)
0.646
95
Pulmonary and Respiratory Medicine
Medicine
2,022
36,245,600
Ancillary treatment of patients with lung disease due to non-tuberculous mycobacteria: a narrative review.
Journal of thoracic disease
J Thorac Dis
14
9
10.21037/jtd-22-410
eng
2,022
9
null
null
null
null
[BACKGROUND AND OBJECTIVE] Non-tuberculous mycobacterial lung disease (NTM-LD) manifests with bronchiectasis, inflammatory bronchiolitis, nodules, and/or cavitation. Bronchiectasis is characterized by permanently dilated airways wherein mucus accumulates, creating a vicious cycle of chronic injurious inflammation and r...
Airway clearance; aspiration; bronchiectasis; gastroesophageal reflux; nutrition; vestibular dysfunction
0.646
95
Pulmonary and Respiratory Medicine
Medicine
2,022
36,245,348
Physical activity, sitting time, neck disability and posture in workers using visual display terminals (VDT).
Work (Reading, Mass.)
Work
74
2
10.3233/WOR-205194
eng
2,023
null
null
null
null
null
[BACKGROUND] Musculoskeletal pain represents a major public health problem. Workers who use visual display terminals (VDT) have suffered an increase in neck pain in recent decades. [OBJECTIVE] The aim of this study was to analyze the relationship between physical activity (PA), sitting time, posture, and neck disabilit...
Exercise; computer terminals; neck pain; posture; sedentary time
null
null
null
null
null
36,244,641
Palliative Care Challenges in Nigeria: A qualitative study of interprofessional perceptions.
Journal of pain and symptom management
J Pain Symptom Manage
65
1
10.1016/j.jpainsymman.2022.10.002
eng
2,023
1
null
2,022
10
14
[CONTEXT] Palliative care awareness, education and practice vary widely across global health systems, especially throughout low- and middle-income countries such as Nigeria. Unfortunately, qualitative investigations into the context, experiences and challenges of Nigerian health care professionals providing palliative ...
Cancer; Education; Nigeria; Palliative care; Training
1.186
171
Anesthesiology and Pain Medicine; Neurology; Nursing
Medicine; Nursing
2,023
36,244,275
Changes in electromyographic activity of latent trigger points after a dry needling intervention: a randomised controlled trial.
Physiotherapy
Physiotherapy
117
null
10.1016/j.physio.2022.09.002
eng
2,022
12
null
2,022
9
7
[OBJECTIVE] To analyse the effects of dry needling (DN) in upper trapezius latent trigger points (LTrPs) on pressure pain threshold (PPT) and surface electromyography (sEMG). [DESIGN] Randomized, double-blind, placebo controlled clinical trial. [SETTINGS] Sports Rehabilitation Laboratory, University of Castilla-La Manc...
Dry needling; Electromyography; Latent trigger point; Upper trapezius
null
null
null
null
null
36,244,077
Expectations of the upcoming birth - A survey of women's self-efficacy and birth positions.
Sexual reproductive healthcare : official journal of the Swedish Association of Midwives
Sex Reprod Healthc
34
null
10.1016/j.srhc.2022.100783
eng
2,022
12
null
2,022
10
5
[BACKGROUND] Adopting an upright sacrum flexible position may facilitate physiological childbirth, which many pregnant women wish for. A positive association between women's choice on birthing position and birthing experience has been found. [OBJECTIVE] The aim of this study was to examine women's preferred birth posit...
Birthing positions; Physiological childbirth; Pregnancy; Self-efficacy
null
null
null
null
null
36,243,704
Effects of physiotherapeutic scoliosis-specific exercise in patients with mild juvenile scoliosis.
BMC musculoskeletal disorders
BMC Musculoskelet Disord
23
1
10.1186/s12891-022-05857-x
eng
2,022
10
15
2,022
10
15
[STUDY DESIGN] A combined retrospective and prospective analysis on the therapeutic effect of physiotherapeutic scoliosis-specific exercise (PSSE) in mild juvenile idiopathic scoliosis (JIS) patients. [BACKGROUND] At present, patients with mild JIS are generally treated by observation without any interventional treatme...
Conservative Treatment; Juvenile Idiopathic Scoliosis; Physiotherapeutic Scoliosis Specific Exercise; The angle of trunk rotation
0.716
131
Orthopedics and Sports Medicine; Rheumatology
Medicine
2,022
36,243,684
Perspectives on cancer screening participation in a highly urbanized region: a Q-methodology study in The Hague, the Netherlands.
BMC public health
BMC Public Health
22
1
10.1186/s12889-022-14312-4
eng
2,022
10
15
2,022
10
15
[BACKGROUND] The Netherlands hosts, as many other European countries, three population-based cancer screening programmes (CSPs). The overall uptake among these CSPs is high, but has decreased over recent years. Especially in highly urbanized regions the uptake rates tend to fall below the minimal effective rate of 70% ...
Cancer screening; I-Change model; Participation; Perspectives; Q-methodology; Uptake
1.307
211
Public Health, Environmental and Occupational Health
Medicine
2,022
36,243,677
A conceptual framework for the exploration of the relationship between systems of paramedicine and system performance.
Australasian emergency care
Australas Emerg Care
26
2
10.1016/j.auec.2022.09.004
eng
2,023
6
null
2,022
10
12
[BACKGROUND] Over the past 60 years since its inception, the Anglo-American Paramedic System has continued to grow and evolve. While brief and fragmented accounts of the differences between systems have been noted in the literature, until recently there has been a paucity of research that explores and identifies sub-mo...
Ambulance; EMS system; Leadership; Paramedic; Structure
0.631
36
Emergency Nursing
Nursing
2,023
36,243,595
Metacarpophalangeal Joint Pyrocarbon Arthroplasty for Osteoarthritis: An Analysis of 44 Arthroplasties.
The Journal of hand surgery
J Hand Surg Am
49
5
10.1016/j.jhsa.2022.08.013
eng
2,024
5
null
2,022
10
13
[PURPOSE] The objective of this study was to analyze postoperative outcomes in a group of patients who underwent metacarpophalangeal (MCP) arthroplasty using a pyrocarbon prosthesis for noninflammatory arthritis. [METHODS] An analysis of 44 MCP joint arthroplasties in 30 patients with 2 years of follow-up over a 12-yea...
Arthroplasty; metacarpophalangeal joint; osteoarthritis; pyrocarbon
0.982
142
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
36,243,581
Ulnar shortening osteotomy for posttraumatic ulnar impaction syndrome in adolescent (younger than 18 years) - Based on the Cha Shin assessment.
Injury
Injury
53
12
10.1016/j.injury.2022.10.004
eng
2,022
12
null
2,022
10
7
[PURPOSE] We performed ordinary ulnar shortening osteotomy (USO) in patients younger than 18 years old with secondary ulnar impaction syndrome (UIS) after traumatic events. Here, we report the clinical and radiologic outcomes with a review of the previous literature through a retrospective case series. [METHODS] Twenty...
Adolescent; Physis; Traumatic; Ulnar impaction; Ulnar shortening
0.698
151
Surgery; Emergency Medicine; Orthopedics and Sports Medicine
Medicine
2,022
36,243,254
Magnetic resonance imaging for evaluation of bowel inflammation and disease activity in Crohn's disease: A systematic review and meta-analysis.
Gastroenterologia y hepatologia
Gastroenterol Hepatol
46
5
10.1016/j.gastrohep.2022.10.004
eng
2,023
5
null
2,022
10
13
[BACKGROUND] The aim of this systematic review and meta-analysis was to determine the performance of magnetic resonance imaging (MRI) in the diagnosis of bowel inflammation and disease activity in Crohn's disease (CD). [METHODS] MEDLINE, Embase and Web of Science databases of biomedical literature were systematically s...
Crohn's disease; Enfermedad de Crohn; Magnetic resonance imaging; Meta-analysis; Systematic review
0.263
35
Gastroenterology; Hepatology
Medicine
2,023
36,242,900
Freezing of gait depends on cortico-subthalamic network recruitment following STN-DBS in PD patients.
Parkinsonism related disorders
Parkinsonism Relat Disord
104
null
10.1016/j.parkreldis.2022.10.002
eng
2,022
11
null
2,022
10
8
[INTRODUCTION] Subthalamic deep-brain-stimulation (STN-DBS) is an effective means to treat Parkinson's disease (PD) symptoms. Its benefit on gait disorders is variable, with freezing of gait (FOG) worsening in about 30% of cases. Here, we investigate the clinical and anatomical features that could explain post-operativ...
Deep brain stimulation; Freezing of gait; Magnetic resonance imaging; Parkinson's disease; Subthalamic nucleus; Tractography
null
null
null
null
null
36,242,626
Brain structural abnormalities and cognitive changes in a patient with 17q21.31 microduplication and early onset dementia: a case report.
Journal of neurology
J Neurol
270
2
10.1007/s00415-022-11423-1
eng
2,023
2
null
2,022
10
15
[OBJECTIVES] We describe brain structural damage and cognitive profile evolution of an adult patient with 17q21.31 microduplication, a rare condition associated with psychomotor delay, behavioural disturbances and poor social interaction. [METHODS] A.B., 57 years old, male, displayed obsessive and repetitive behaviours...
17q21.31 microduplication; Case report; Cognitive changes; Voxel-based morphometry; Young-onset dementia
1.552
168
Neurology; Neurology
Medicine; Neuroscience
2,023
36,242,530
Guidelines for Cystic Fibrosis Carrier Screening in the Prenatal/Preconception Period.
Obstetrical gynecological survey
Obstet Gynecol Surv
77
10
10.1097/OGX.0000000000001062
eng
2,022
10
null
null
null
null
[IMPORTANCE] Cystic fibrosis (CF) is one of the most common autosomal recessive disorders. Carrier screening for CF should be offered to all women considering becoming pregnant or who are pregnant. Understanding the available screening tests, their limitations, and the benefits of screening is of paramount importance t...
null
null
null
null
null
null
36,242,017
Reading activities compensate for low education-related cognitive deficits.
Alzheimer's research therapy
Alzheimers Res Ther
14
1
10.1186/s13195-022-01098-1
eng
2,022
10
14
2,022
10
14
[BACKGROUND] The incidence of cognitive impairment is increasing with an aging population. Developing effective strategies is essential to prevent dementia. Higher education level is associated with better baseline cognitive performance, and reading activities can slow down cognitive decline. However, it is unclear whe...
Cognition; Education; Reading activities
null
null
null
null
null
36,241,997
TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway.
Journal of neuroinflammation
J Neuroinflammation
19
1
10.1186/s12974-022-02619-3
eng
2,022
10
14
2,022
10
14
[BACKGROUND] Microglia, the innate immune cells in the central nervous system, play an essential role in brain homeostasis, neuroinflammation and brain infections. Dysregulated microglia, on the other hand, are associated with neurodegenerative diseases, yet the mechanisms underlying pro-inflammatory gene expression in...
CREB; Inflammation; Retina; TREM2; Tropomyosin 1
2.439
168
Cellular and Molecular Neuroscience; Immunology; Neurology; Neuroscience
Immunology and Microbiology; Neuroscience
2,022
36,241,972
MSPCD: predicting circRNA-disease associations via integrating multi-source data and hierarchical neural network.
BMC bioinformatics
BMC Bioinformatics
23
Suppl 3
10.1186/s12859-022-04976-5
eng
2,022
10
14
2,022
10
14
[BACKGROUND] Increasing evidence shows that circRNA plays an essential regulatory role in diseases through interactions with disease-related miRNAs. Identifying circRNA-disease associations is of great significance to precise diagnosis and treatment of diseases. However, the traditional biological experiment is usually...
Circrna-disease associations; High-order features; Multi-source data; Neural network
1.1
251
Applied Mathematics; Biochemistry; Computer Science Applications; Molecular Biology; Structural Biology
Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics
2,022
36,240,990
Independent inter and intra-observer agreement of the Schizas's classification of degenerative lumbar stenosis: Comparison among three levels of surgical training.
Revista espanola de cirugia ortopedica y traumatologia
Rev Esp Cir Ortop Traumatol
67
3
10.1016/j.recot.2022.10.003
eng
2,023
null
null
2,022
10
12
[INTRODUCTION AND OBJECTIVES] Lumbar spinal stenosis is a common age-related condition that affects the quality of life. Multiple classifications have been developed to quantify the severity of stenosis affecting comparison between studies and homogenous communication among surgeons and researchers. Even though this cl...
Acuerdo independiente; Estenosis espinal lumbar; Independent agreement; Lumbar spinal stenosis; Schizas's classification
0.228
20
Orthopedics and Sports Medicine; Surgery
Medicine
2,023
36,240,956
Association of glycated albumin to hemoglobin A1c ratio with all-cause and cardiovascular mortality among US adults: A population-based cohort study.
Diabetes research and clinical practice
Diabetes Res Clin Pract
193
null
10.1016/j.diabres.2022.110116
eng
2,022
11
null
2,022
10
12
[AIMS] To investigate the association of glycated albumin to hemoglobin A1c (GA/HbA1c) ratio, an indicator of blood glucose fluctuations, with all-cause and cardiovascular mortality among US adults. [METHODS] This cohort study used data from the National Health and Nutrition Examination Survey 1999-2004. Participants w...
Epidemiology; Glycated albumin; Glycated albumin to HbA1c ratio; Hemoglobin A1c; Mortality; National Health and Nutrition Examination Survey
1.634
146
Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,240,715
Histopathological scoring system role in evaluation of electronic cigarette's impact on respiratory pathway in albino rat: Biochemical, histo-morphometric and ultrastructural study.
Tissue cell
Tissue Cell
79
null
10.1016/j.tice.2022.101945
eng
2,022
12
null
2,022
9
28
[BACKGROUND] Electronic cigarettes have gained growing popularity especially among adolescents and young adults. Although the dominant consideration by consumers and the companies claims, whether electronic smoking is indeed a much safer alternative to traditional smoking is hotly debated. [AIM] To declare the biochemi...
E-cigarette; E-liquid; Lung; Nicotine; Respiratory epithelium
null
null
null
null
null
36,240,518
Standardizing Tobacco Cessation Counseling Using the 5 A's Intervention.
Journal of nursing care quality
J Nurs Care Qual
38
2
10.1097/NCQ.0000000000000671
eng
null
null
null
2,022
10
12
[BACKGROUND] Tobacco use is the leading cause of preventable death due to cardiovascular disease. [LOCAL PROBLEM] Tobacco cessation counseling (TCC) is varied among providers, leading to suboptimal willingness to make a quit attempt. [METHODS] We used a quality improvement framework to pilot the 5 A's for TCC from Apri...
null
null
null
null
null
null
36,240,005
Lisaftoclax in Combination with Alrizomadlin Overcomes Venetoclax Resistance in Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia: Preclinical Studies.
Clinical cancer research : an official journal of the American Association for Cancer Research
Clin Cancer Res
29
1
10.1158/1078-0432.CCR-22-0978
eng
2,023
1
4
null
null
null
[PURPOSE] Despite approval of B-cell lymphoma (BCL)-2 inhibitor venetoclax for certain hematologic malignancies, its broader clinical benefit is curtailed by resistance. Our study aimed to determine if treatment with novel anticancer agents targeting BCL-2 and mouse double minute 2 (MDM2) could overcome venetoclax resi...
null
4.623
392
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,240,004
Impact of the COVID-19 Pandemic on the Implementation of Mobile Health to Improve the Uptake of Hydroxyurea in Patients With Sickle Cell Disease: Mixed Methods Study.
JMIR formative research
JMIR Form Res
6
10
10.2196/41415
eng
2,022
10
14
2,022
10
14
[BACKGROUND] Hydroxyurea therapy is effective for reducing complications related to sickle cell disease (SCD) and is recommended by National Health Lung and Blood Institute care guidelines. However, hydroxyurea is underutilized, and adherence is suboptimal. We wanted to test a multilevel mobile health (mHealth) interve...
adherence; hydroxycarbamide; implementation science; self-efficacy; sickle cell anemia
0.592
31
Medicine; Health Informatics
Medicine
2,022
36,239,966
Characterization of the Retinal Microvasculature and FAZ Changes in Ischemic Stroke and Its Different Types.
Translational vision science technology
Transl Vis Sci Technol
11
10
10.1167/tvst.11.10.21
eng
2,022
10
3
null
null
null
[PURPOSE] This study aimed to assess morphological changes in the retinal microvasculature and foveal avascular zone (FAZ) in patients with ischemic stroke and its different subtypes. [METHODS] Thirty-three patients with ischemic stroke (14 with nonlacunar infarction and 19 with lacunar infarction) and 27 control parti...
null
null
null
null
null
null
36,239,940
Association of Neighborhood Conditions and Resources for Children With Life Expectancy at Birth in the US.
JAMA network open
JAMA Netw Open
5
10
10.1001/jamanetworkopen.2022.35912
eng
2,022
10
3
2,022
10
3
[IMPORTANCE] To address inequities in life expectancy, we must understand the associations of modifiable socioeconomic and structural factors with life expectancy. However, the association of limited neighborhood resources and deleterious physical conditions with life expectancy is not well understood. [OBJECTIVE] To e...
null
4.108
154
Medicine
Medicine
2,022
36,239,783
Transcutaneous electrical acupoint stimulation for suspected laryngopharyngeal reflux disease.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Eur Arch Otorhinolaryngol
280
4
10.1007/s00405-022-07698-9
eng
2,023
4
null
2,022
10
14
[PURPOSE] To determine the efficacy of transcutaneous electrical acupoint stimulation (TEAS) combined with proton pump inhibitor (PPI) therapy on symptoms and signs of patients with suspected laryngopharyngeal reflux disease (LPRD). [METHODS] This was a prospective randomized controlled study. Seventy patients with ref...
Laryngopharyngeal reflux disease; Proton pump inhibitor; Transcutaneous electrical acupoint stimulation; Treatment
0.792
94
Otorhinolaryngology; Medicine
Medicine
2,023
36,239,761
Evaluation of resuscitation with angiography, percutaneous techniques and operative repair (RAPTOR): hybrid suite introduction and initial use at a level I urban trauma centre.
European journal of trauma and emergency surgery : official publication of the European Trauma Society
Eur J Trauma Emerg Surg
49
2
10.1007/s00068-022-02115-6
eng
2,023
4
null
2,022
10
14
[PURPOSE] The aim of this study was to describe the utilization of the RAPTOR suite (hybrid theatre) for trauma patients. Ideally, this is used to achieve haemorrhage control in time-critical patients that may require damage control surgery (DCS) and/or interventional radiological (IR) procedures concurrently. [METHODS...
Damage control; Haemorrhage; Hybrid theatre; Interventional radiology; RAPTOR suite; Trauma
0.661
54
Critical Care and Intensive Care Medicine; Emergency Medicine; Orthopedics and Sports Medicine; Surgery
Medicine
2,023
36,239,641
Aberrant Mucin Expression Profiles Associate With Pediatric Inflammatory Bowel Disease Presentation and Activity.
Inflammatory bowel diseases
Inflamm Bowel Dis
29
4
10.1093/ibd/izac217
eng
2,023
4
3
null
null
null
[BACKGROUND] Intestinal mucosal healing is nowadays preferred as the therapeutic endpoint in inflammatory bowel disease (IBD), but objective measurements at the molecular level are lacking. Because dysregulated mucin expression is suggested to be involved in mucosal barrier dysfunction in IBD, we investigated mucin exp...
biomarkers; intestinal mucosal barrier; pediatric IBD
1.55
183
Gastroenterology; Immunology and Allergy
Medicine
2,023
36,239,574
Feasibility of implementing a web-based tool built from pharmacy claims data (e-MEDRESP) to monitor adherence to respiratory medications in primary care.
Current medical research and opinion
Curr Med Res Opin
38
12
10.1080/03007995.2022.2135835
eng
2,022
12
null
2,022
11
4
[OBJECTIVE] e-MEDRESP is a novel web-based tool that provides easily interpretable information on patient adherence to asthma/chronic obstructive pulmonary disease (COPD) medications, using pharmacy claims data. This study investigated the feasibility of implementing e-MEDRESP in primary care. [MATERIAL AND METHODS] In...
COPD; Medication adherence; asthma; drug monitoring; health records; medical records systems
0.643
125
Medicine
Medicine
2,022
36,239,318
Hyperfunctional Laryngeal Behavior: Is It the Cause or Consequence of Vocal Fold Polyps?
The Annals of otology, rhinology, and laryngology
Ann Otol Rhinol Laryngol
132
9
10.1177/00034894221129906
eng
2,023
9
null
2,022
10
14
[OBJECTIVES] To evaluate the relationship between arytenoid adduction asymmetry (AAA) and the demographic and morphological characteristics of true vocal fold (TVF) polyps and establish the cause and effect relationship between AAA and TVF polyps. [METHODS] Videolaryngostroboscopic findings of 163 patients with TVF pol...
arytenoid cartilage; glottis/physiopathology; laryngoscopy; muscle tonus; polyps
0.615
107
Medicine; Otorhinolaryngology
Medicine
2,023
36,239,069
Hepatitis C virus monitoring in inpatient psychiatry: Doctors' practice.
Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists
Australas Psychiatry
31
1
10.1177/10398562221133277
eng
2,023
2
null
2,022
10
14
[OBJECTIVES] Current guidelines recommend routine Hepatitis C virus (HCV) monitoring in people with serious mental illness. We sought to determine the rates at which doctors practising in inpatient psychiatry units monitor the HCV exposure risk and HCV infection status of their patients. [METHODS] Electronic medical re...
Hepatitis C virus; hepatitis C risk factors; inpatient; serious mental illness
0.504
49
Psychiatry and Mental Health
Medicine
2,023
36,238,993
Microarray data reveal potential genes that regulate triple-negative breast cancer.
The Journal of international medical research
J Int Med Res
50
10
10.1177/03000605221130188
eng
2,022
10
null
null
null
null
[OBJECTIVE] Triple-negative breast cancer (TNBC) is characterized by a lack of targeted therapies and poor patient prognosis, and its underlying pathological mechanisms remain unclear. This study aimed to identify potential key genes and related pathways that are required for TNBC development. [METHODS] We screened the...
Bioinformatics; CDK1; cell cycle; key genes; miR-143-3p; triple-negative breast cancer
0.393
74
Biochemistry; Biochemistry; Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,238,957
Risk Factors for Midline Catheter Failure: A Secondary Analysis of an Existing Trial.
Therapeutics and clinical risk management
Ther Clin Risk Manag
18
null
10.2147/TCRM.S383502
eng
2,022
null
null
2,022
10
7
[OBJECTIVE] While midline catheters (MCs) are considered to be a reliable form of vascular access, up to 25% of the placements culminate in failure. We aimed to explore risk factors for MC failure. [METHODS] We performed an analysis of existing randomized controlled trial data involving a comparison of two midline cath...
complications; midline catheter; midline catheter failure; risk factors; vascular access; vesicants
0.652
74
Pharmacology, Toxicology and Pharmaceutics; Safety Research; Chemical Health and Safety; Medicine; Pharmacology
Chemical Engineering; Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,022
36,238,940
An Exploratory Study on the Mediating Effect of Clinical Competence in the Relationship Between Grit and Field Adaptation in Newly Graduated Nurses.
SAGE open nursing
SAGE Open Nurs
8
null
10.1177/23779608221127979
eng
2,022
null
null
2,022
10
9
[INTRODUCTION] Even under difficult situations, individuals with psychological resources such as positive psychological capital and resilience are less likely to consider turnover. Grit is a psychological factor that predicts success at work in other industries, but little is known about its impact on newly graduated n...
clinical competence; field adaptation; grit; mediating effect; newly graduated nurses; self-questionnaire
0.443
24
Nursing
Nursing
2,022
36,238,287
Time evolution of cytokine profiles associated with mortality in COVID-19 hospitalized patients.
Frontiers in immunology
Front Immunol
13
null
10.3389/fimmu.2022.946730
eng
2,022
null
null
2,022
9
27
[BACKGROUND] High cytokine levels have been associated with severe COVID-19 disease. Although many cytokine studies have been performed, not many of them include combinatorial analysis of cytokine profiles through time. In this study we investigate the association of certain cytokine profiles and its evolution, and mor...
COVID-19; cytokines; hospitalized patients; mortality; principal component analysis - PCA
2.022
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
36,237,759
Role of Neoadjuvant Chemotherapy in Ovarian Serous Cancer Followed by Debulking.
Cureus
Cureus
14
9
10.7759/cureus.28909
eng
2,022
9
null
2,022
9
7
[BACKGROUND] Ovarian cancers are one of the most common gynecological cancers and serous tumor is one of the most common histological form of extrauterine female genital tract tumors. While ovarian serous carcinoma is a well-studied human gynecologic malignancy, this high-grade tumor remains lethal. [CASE DESCRIPTION] ...
abdominal pain; ca-125 levels; laparotomy; neoadjuvant chemotherapy; ovary; serous cystadenocarcinoma
null
null
null
null
null
36,237,655
Exploring the Effects of a Neck Strengthening Program on Purposeful Soccer Heading Biomechanics and Neurocognition.
International journal of sports physical therapy
Int J Sports Phys Ther
17
6
10.26603/001c.38327
eng
2,022
null
null
2,022
10
2
[BACKGROUND] Cervical (neck) strengthening has been proposed as an important factor in concussion prevention. The purpose of the study was to determine if a six-week cervical strengthening program affected neurocognition and purposeful soccer heading biomechanics. The hypothesis was that the neck strengthening program ...
CNS vital signs; cervical strength; concussion prevention
0.398
22
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Orthopedics and Sports Medicine
Health Professions; Medicine
2,022
36,233,711
Sex-Related Differences in Clinical Outcomes in Patients with Atrial Fibrillation and Coronary Artery Disease: A Sub-Study of the MISOAC-AF Randomized Controlled Trial.
Journal of clinical medicine
J Clin Med
11
19
10.3390/jcm11195843
eng
2,022
10
1
2,022
10
1
[BACKGROUND] There is limited "real-world" data on the prognostic role of gender in comorbid atrial fibrillation (AF) and coronary artery disease (CAD). [METHODS] In this post-hoc analysis of the MISOAC-AF randomized trial (NCT: 02941978), consecutive patients with AF and CAD who were discharged from the cardiology war...
atrial fibrillation; coronary artery disease; prognosis; sex
0.935
132
Medicine
Medicine
2,022