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36,191,570
Lenvatinib Might Induce Activation of Host Immunity in Patients with Hepatocellular Carcinoma.
Oncology
Oncology
101
1
10.1159/000527306
eng
2,023
null
null
2,022
10
3
[INTRODUCTION] Atezolizumab, an immune checkpoint inhibitor, plus bevacizumab, a monoclonal antibody that binds to vascular endothelial growth factor (VEGF), is an approved first-line systemic treatment for unresectable hepatocellular carcinoma (HCC). Immune checkpoint inhibitors are more effective in patients with HCC...
Hepatocellular carcinoma; Host immunity; Lenvatinib; T helper 1/T helper 2 balance
null
null
null
null
null
36,191,466
Screening patients with autoimmune endocrine disorders for cytokine autoantibodies reveals monogenic immune deficiencies.
Journal of autoimmunity
J Autoimmun
133
null
10.1016/j.jaut.2022.102917
eng
2,022
12
null
2,022
9
30
[BACKGROUND] Autoantibodies against type I interferons (IFN) alpha (α) and omega (ω), and interleukins (IL) 17 and 22 are a hallmark of autoimmune polyendocrine syndrome type 1 (APS-1), caused by mutations in the autoimmune regulator (AIRE) gene. Such antibodies are also seen in a number of monogenic immunodeficiencies...
Autoantibodies; Autoimmune polyendocrine syndrome type 1 (APS-1); Interleukin-22 (IL22); Next generation sequencing
2.594
147
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
36,191,175
Synchronous Teleconsultation and Monitoring Service Targeting COVID-19: Leveraging Insights for Postpandemic Health Care.
JMIR medical informatics
JMIR Med Inform
10
12
10.2196/37591
eng
2,022
12
22
2,022
12
22
[BACKGROUND] Although a great number of teleconsultation services have been developed during the COVID-19 pandemic, studies assessing usability and health care provider satisfaction are still incipient. [OBJECTIVE] This study aimed to describe the development, implementation, and expansion of a synchronous teleconsulta...
COVID-19; delivery of health care; digital health; mobile health; primary health care; public health; remote care; remote consultation; telehealth; telemedicine; telemonitoring; text message; usability
0.963
55
Health Informatics; Health Information Management
Health Professions; Medicine
2,022
36,190,331
Ramucirumab for Patients with Advanced Hepatocellular Carcinoma and Elevated Alpha Fetoprotein Following Non-Sorafenib Systemic Therapy: An Expansion Cohort of REACH-2.
The oncologist
Oncologist
27
12
10.1093/oncolo/oyac183
eng
2,022
12
9
null
null
null
[BACKGROUND] Ramucirumab is indicated for patients with advanced hepatocellular carcinoma (HCC) and α-fetoprotein (AFP) ≥400 ng/mL following sorafenib. Here, we prospectively studied ramucirumab following non-sorafenib systemic therapies. [MATERIALS AND METHODS] This open-label, non-comparative cohort of REACH-2 enroll...
advanced hepatocellular carcinoma (HCC); non-sorafenib; ramucirumab
1.859
199
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,190,214
Prevalence of renal involvement among pediatric patients hospitalized due to coronavirus disease 2019: A multicenter study.
Archivos argentinos de pediatria
Arch Argent Pediatr
120
5
10.5546/aap.2022.eng.310
eng
2,022
10
null
2,022
8
12
[INTRODUCTION] Renal involvement among pediatric patients with coronavirus disease 2019 (COVID-19) ranges between 1.2% and 44%. Given the limited information available locally, the primary objective of this study was to estimate the prevalence of renal involvement in our setting. [POPULATION AND METHODS] Cross-sectiona...
proteinuria; COVID-19; acute kidney injury; child; hematuria
null
null
null
null
null
36,190,111
Derivation and Validation of a Phenoconversion-Related Pattern in Idiopathic Rapid Eye Movement Behavior Disorder.
Movement disorders : official journal of the Movement Disorder Society
Mov Disord
38
1
10.1002/mds.29236
eng
2,023
1
null
2,022
10
3
[BACKGROUND] Idiopathic rapid eye movement sleep behavior disorder (iRBD) represents the prodromal stage of α-synucleinopathies. Reliable biomarkers are needed to predict phenoconversion. [OBJECTIVE] The aim was to derive and validate a brain glucose metabolism pattern related to phenoconversion in iRBD (iRBDconvRP) us...
disease-related pattern; fluorodeoxyglucose positron emitting tomography; phenoconversion; rapid eye movement sleep behavior disorder
2.464
238
Neurology; Neurology
Medicine; Neuroscience
2,023
36,189,777
Association of cannabis use during pregnancy with severe acute respiratory syndrome coronavirus 2 infection: a retrospective cohort study.
Addiction (Abingdon, England)
Addiction
118
2
10.1111/add.16056
eng
2,023
2
null
2,022
10
12
[BACKGROUND AND AIMS] Cannabis use is increasingly common among pregnant individuals and might be a risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We aimed to test whether prenatal cannabis use is associated with increased risk of SARS-CoV-2 infection during pregnancy. [DESIGN] ...
COVID-19; Cannabis; SARS-CoV-2; marijuana; pregnancy; prenatal
2.129
224
Medicine; Psychiatry and Mental Health
Medicine
2,023
36,189,381
Sublingual misoprostol vs. oral misoprostol solution for induction of labor: A retrospective study.
Frontiers in surgery
Front Surg
9
null
10.3389/fsurg.2022.968372
eng
2,022
null
null
2,022
9
15
[INTRODUCTION] Induction of labor (IOL) is one of the most common obstetrical procedures, with an increasing rate. The prostaglandin E1 analogue misoprostol is frequently used as a primary method of labor induction. The optimal dose and route of administration is yet to be ascertained. [AIM] To compare efficiacy and sa...
human; induction of labour; misoprostol; oral; oral misoprostol solution; pregnancy; retrospective; sublingual
0.459
48
Surgery
Medicine
2,022
36,189,196
Short-Term Outcomes of Elective High-Risk PCI with Extracorporeal Membrane Oxygenation Support: A Single-Centre Registry.
Journal of interventional cardiology
J Interv Cardiol
2022
null
10.1155/2022/7245384
eng
2,022
null
null
2,022
9
16
[BACKGROUND] If surgical revascularization is not feasible, high-risk PCI is a viable option for patients with complex coronary artery disease. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) provides hemodynamic support in patients with a high risk for periprocedural cardiogenic shock. [OBJECTIVE] This stud...
null
0.609
58
Cardiology and Cardiovascular Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
36,189,134
A Novel Missense CASR Gene Sequence Variation Resulting in Familial Hypocalciuric Hypercalcemia.
AACE clinical case reports
AACE Clin Case Rep
8
5
10.1016/j.aace.2022.05.002
eng
2,022
null
null
2,022
5
17
[BACKGROUND/OBJECTIVE] Familial hypocalciuric hypercalcemia (FHH) is an uncommon cause of hypercalcemia; however, it is important to consider and rule out in patients with suspected primary hyperparathyroidism (PHPT), ideally, before proceeding with surgery. Herein, we present a patient where this process identified a ...
CCCR, calcium creatinine clearance ratio; CaSR, calcium-sensing receptor; FHH, familial hypocalciuric hypercalcemia; PHPT, primary hyperparathyroidism; PTH, parathyroid hormone; RR, reference range; Sherloc classification system; VUS, variant of unknown significance; familial hypocalciuric hypercalcemia (FHH); genetic ...
0.288
15
Endocrinology, Diabetes and Metabolism
Medicine
2,022
36,188,894
Predicting Individual Treatment Response to rTMS for Motor Recovery After Stroke: A Review and the CanStim Perspective.
Frontiers in rehabilitation sciences
Front Rehabil Sci
3
null
10.3389/fresc.2022.795335
eng
2,022
null
null
2,022
2
10
[BACKGROUND] Rehabilitation is critical for reducing stroke-related disability and improving quality-of-life post-stroke. Repetitive transcranial magnetic stimulation (rTMS), a non-invasive neuromodulation technique used as stand-alone or adjunct treatment to physiotherapy, may be of benefit for motor recovery in subgr...
motor recovery; prediction; rehabilitation; repetitive transcranial magnetic stimulation; review; stroke
null
14
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation
Health Professions; Medicine
2,022
36,188,879
Prevalence and Molecular Evaluation of Hepatitis C Virus Infection among Multi-transfused Thalassemia Patients in South of Iran.
Oman medical journal
Oman Med J
37
5
10.5001/omj.2022.85
eng
2,022
9
null
2,022
9
30
[OBJECTIVES] Information regarding the magnitude of hepatitis C virus (HCV) infection among thalassemia patients is of great importance for health care providers to assess blood safety and improve the quality of screening systems. Therefore, this study evaluated the prevalence, risk factors, and genotypic pattern of HC...
Genotype; Hepatitis C; Iran; Prevalence; Risk Factor; beta-Thalassemia
0.441
49
Medicine
Medicine
2,022
36,188,364
New evidence on the association of occupation with amyotrophic lateral sclerosis: A register-based case-control study in Finland.
Frontiers in neurology
Front Neurol
13
null
10.3389/fneur.2022.859824
eng
2,022
null
null
2,022
9
14
[OBJECTIVES] Amyotrophic lateral sclerosis (ALS) is a serious neurodegenerative disease that usually leads to death within a few years from diagnosis. The risk factors for ALS are still largely unknown. However, it is assumed that environmental factors play a role in disease onset. Occupation is suggested as a potentia...
amyotrophic lateral sclerosis (ALS); case-control; epidemiology; occupation; register study
0.978
118
Neurology; Neurology
Medicine; Neuroscience
2,022
36,188,106
Meta-Analysis of Dyslipidemia and Blood Lipid Parameters on the Risk of Primary Open-Angle Glaucoma.
Computational and mathematical methods in medicine
Comput Math Methods Med
2022
null
10.1155/2022/1122994
eng
2,022
null
null
2,022
9
21
[OBJECTIVE] We aimed to explore the effect of blood lipid parameters on the risk of primary open-angle glaucoma (POAG) by meta-analysis. [METHODS] The databases of PubMed, Scopus, CNKI, and Wanfang were systematically searched from inception to April 2022, and the relevant research literature was obtained, screened, an...
null
null
null
null
null
null
36,187,856
Effect of body temperature on the cyclic fatigue resistance of the nickel-titanium endodontic instruments: A systematic review and meta-analysis of in vitro studies.
Journal of conservative dentistry : JCD
J Conserv Dent
25
4
10.4103/jcd.jcd_55_22
eng
2,022
null
null
2,022
8
2
[AIM] The aim of this systematic review was to compare the effect of body temperature (I) on the cyclic fatigue resistance (O) of nickel-titanium (NiTi) endodontic instruments (P) to that of room temperature (C). [METHODS] The study was registered in the PROSPERO database (CRD42020204286). A systematic search in PubMed...
Cyclic fatigue; dental instrument; endodontics; meta.analysis; nickel-titanium; root canal preparation/instrumentation; root canal therapy/instrumentation; temperature
null
null
null
null
null
36,187,674
Investigation of a group of Iranian theater artists' mental health and attitude toward patients with mental disorders.
Frontiers in public health
Front Public Health
10
null
10.3389/fpubh.2022.990815
eng
2,022
null
null
2,022
9
15
[INTRODUCTION] Stigmatizing attitude toward patients with severe mental disorders is one of the main obstacles of improving the mental health of societies. Media plays an important role in how the public views mental health issues. Thus, we have performed this study to investigate the Iranian theater artists' mental he...
art; community psychiatry; mental health; mental illness; social stigma
1.125
119
Public Health, Environmental and Occupational Health
Medicine
2,022
36,187,651
Promotion of knowledge, attitude, and practice among medical undergraduates regarding infection control measures during COVID-19 pandemic.
Frontiers in public health
Front Public Health
10
null
10.3389/fpubh.2022.932465
eng
2,022
null
null
2,022
9
15
[BACKGROUND] Medical students are exposed to many serious healthcare-associated infections throughout their learning and training time particularly during a pandemic like COVID-19. Therefore, promotion of their knowledge, attitude, and practice regarding infection control measures is a mandatory action. [OBJECTIVE] Thi...
COVID-19; infection control; knowledge; medical students; medical undergraduates; skills; training
1.125
119
Public Health, Environmental and Occupational Health
Medicine
2,022
36,187,365
A randomized controlled trial of a multicomponent online stress reduction intervention in inflammatory bowel disease.
Therapeutic advances in gastroenterology
Therap Adv Gastroenterol
15
null
10.1177/17562848221127238
eng
2,022
null
null
2,022
9
27
[BACKGROUND] Psychological stress negatively impacts inflammatory bowel disease (IBD) outcomes. Patients have prioritized access to online interventions; yet, the data on these have been limited by mixed in-person/online interventions, low adherence, and non-randomized controlled trial (RCT) design. [OBJECTIVES] We ass...
inflammatory bowel disease; online intervention; stress reduction
1.226
71
Gastroenterology
Medicine
2,022
36,187,230
lncRNA DARS-AS1 Modulates TSPAN1-Mediated ITGA2 Hypomethylation by Interaction with miR-194-5p Thus Promoting Ovarian Cancer Progression.
Stem cells international
Stem Cells Int
2022
null
10.1155/2022/4041550
eng
2,022
null
null
2,022
9
22
[OBJECTIVE] Ovarian cancer (OC) is usually called the "silent killer" due to its asymptomatic characteristics until advanced stages, thus being a significant threat to female health worldwide. In this work, we characterized an oncogenic DARS-AS1 role in OC. [METHODS] The aggressiveness behaviors of the OC cell model we...
null
0.857
103
Molecular Biology; Cell Biology
Biochemistry, Genetics and Molecular Biology
2,022
36,187,216
Stent fractures in the superficial femoral artery: predisposing factors and their implications.
Jornal vascular brasileiro
J Vasc Bras
21
null
10.1590/1677-5449.202000142
eng
2,022
null
null
2,022
9
19
[BACKGROUND] Fractures in stents implanted in the superficial femoral artery (SFA) are recognized complications of endovascular management of this arterial territory. [OBJECTIVES] The objective of this study was to determine the prevalence of fractures in stents implanted in the SFA and to identify predisposing factors...
endovascular procedures; peripheral arterial disease; stents
null
null
null
null
null
36,187,194
Integrative analysis of DNA methylation and gene expression identifies genes associated with biological aging in Alzheimer's disease.
Alzheimer's dementia (Amsterdam, Netherlands)
Alzheimers Dement (Amst)
14
1
10.1002/dad2.12354
eng
2,022
null
null
2,022
9
20
[INTRODUCTION] The acceleration of biological aging is a risk factor for Alzheimer's disease (AD). Here, we performed weighted gene co-expression network analysis (WGCNA) to identify modules and dysregulated genesinvolved in biological aging in AD. [METHODS] We performed WGCNA to identify modules associated with biolog...
AD biomarker; Alzheimer's disease; CX3CR1; biological aging; epigenetic clocks; telomere length
null
null
null
null
null
36,187,005
Coronary access following ACURATE neo implantation for transcatheter aortic valve-in-valve implantation: Ex vivo analysis in patient-specific anatomies.
Frontiers in cardiovascular medicine
Front Cardiovasc Med
9
null
10.3389/fcvm.2022.902564
eng
2,022
null
null
2,022
9
14
[BACKGROUND] Coronary access after transcatheter aortic valve implantation (TAVI) with supra-annular self-expandable valves may be challenging or un-feasible. There is little data concerning coronary access following transcatheter aortic valve-in-valve implantation (ViV-TAVI) for degenerated surgical bioprosthesis. [AI...
aortic stenosis; coronary access; transcatheter aortic valve implantation (TAVI)
1.391
81
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,186,940
Correlation of Obesity and Overweight with Cervical Vascular Function Among Healthy Populations.
Diabetes, metabolic syndrome and obesity : targets and therapy
Diabetes Metab Syndr Obes
15
null
10.2147/DMSO.S383880
eng
2,022
null
null
2,022
9
25
[PURPOSE] To study the effects of obesity and overweight on carotid vascular function among healthy populations by carotid ultrasound (CAU) and transcranial Doppler (TCD). [MATERIALS AND METHODS] Basic clinical characteristics, CAU and TCD parameters were collected from recruited healthy individuals. Firstly, all parti...
basilar artery; internal carotid artery; obesity; overweight; vertebral artery
0.851
71
Internal Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,186,896
Saline versus Balanced Crystalloids for Adults with Aneurysmal Subarachnoid Hemorrhage: A Subgroup Analysis of the SMART Trial.
Stroke (Hoboken, N.J.)
Stroke Vasc Interv Neurol
2
4
10.1161/svin.121.000128
eng
2,022
7
null
2,022
5
8
[BACKGROUND] Whether the composition of intravenous crystalloid solutions affects outcomes in adults with aneurysmal subarachnoid hemorrhage (aSAH) remains unknown. Therefore, we determined whether the use of saline is associated with lower risk of disability and death in aSAH patients compared to balanced crystalloids...
Clinical Trial; Critical Care; Intravenous Fluids; Subarachnoid hemorrhage
2.746
370
Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience
Medicine; Neuroscience; Nursing
2,022
36,186,799
Case study of cervical cancer prevention in two sub-Saharan African countries: Rwanda and Sierra Leone.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.928685
eng
2,022
null
null
2,022
9
15
[BACKGROUND] Cervical cancer is a public health issue of global concern. It is a preventable disease but continues to threaten the lives of women, especially in developing countries in sub-Saharan Africa. [METHODS] We selected two African countries in sub-Saharan Africa (the Republic of Rwanda and the Republic of Sierr...
Rwanda; Sierra Leone; cervical cancer; screening; vaccination
0.926
102
Medicine
Medicine
2,022
36,186,145
Evaluation of the Nystagmus Information Pack.
The British and Irish orthoptic journal
Br Ir Orthopt J
18
1
10.22599/bioj.269
eng
2,022
null
null
2,022
9
15
[INTRODUCTION] In response to the need for easily accessible, high-quality information about nystagmus, the Nystagmus Information Pack was created and made freely available online in 2017. This study was undertaken to evaluate the content and accessibility of the Nystagmus Information Pack. [METHODS] Clinicians, eye cl...
nystagmus; patient information; questionnaire
null
null
null
null
null
36,186,091
Single-Dose Intramuscular Toxicity Study of SU-Eohyeol Pharmacopuncture in Rats.
Journal of pharmacopuncture
J Pharmacopuncture
25
3
10.3831/KPI.2022.25.3.268
eng
2,022
9
30
null
null
null
[OBJECTIVES] This toxicological study was performed to assess for potential toxicity and to determine the approximate lethal dose of SU-Eohyeol pharmacopuncture (SUEP) following a single intramuscular injection of SUEP into male and female Sprague-Dawley (SD) rats. [METHODS] The groups in our experiment consisted of an...
acupuncture; cervi parvum cornu; jungsongouhyul pharmacopuncture; safety; single intramuscular toxicity; su-eohyeol
0.394
29
Complementary and Alternative Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,185,568
Laparoscopic appendectomy, stump closure and endoloops: A meta-analysis.
World journal of gastrointestinal surgery
World J Gastrointest Surg
14
9
10.4240/wjgs.v14.i9.1060
eng
2,022
9
27
null
null
null
[BACKGROUND] Acute appendicitis (AA) is one of the main indications for urgent surgery. Laparoscopic appendectomy (LA) has shown advantages in terms of clinical results and cost-effectiveness, even if there is still controversy about different devices to utilize, especially with regards to the endoloop (EL) vs endostap...
Acute appendicitis; Endoloops; Laparoscopic appendectomy; Post-operative complications; Stapler
null
null
null
null
null
36,185,537
Percent positivity and phylogenetic analysis of Mycoplasma gallisepticum and Mycoplasma synoviae in commercial poultry from the different States of India.
Veterinary world
Vet World
15
7
10.14202/vetworld.2022.1843-1851
eng
2,022
7
null
2,022
7
28
[BACKGROUND AND AIM] The Indian and global poultry industries suffer significant economic losses due to Mycoplasma gallisepticum (MG) and Mycoplasma synoviae (MS) infections, which adversely affect egg production, hatchability, weight gain, and feed efficiency in farms, thus decreasing the overall production efficiency...
India; Mycoplasma gallisepticum; Mycoplasma synoviae; epidemiology; phylogeny; polymerase chain reaction
0.433
56
Veterinary
Veterinary
2,022
36,185,238
Single cell sequencing analysis and transcriptome analysis constructed the liquid-liquid phase separation(LLPS)-related prognostic model for endometrial cancer.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.1005472
eng
2,022
null
null
2,022
9
14
[BACKGROUND] Endometrial cancer is one of the most common gynecological tumors in developed countries. Our understanding of the pathogenesis of endometrial cancer and the changes in the immune microenvironment are still unclear. It is necessary to explore new biomarkers to guide the diagnosis and treatment of endometri...
endometrial cancer; immune microenvironment; liquid-liquid phase separation; single cell sequencing data; transcriptome data
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,185,186
Clinical features and surgical outcomes of young patients with lung adenocarcinoma manifesting as ground glass opacity.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.979522
eng
2,022
null
null
2,022
9
14
[BACKGROUND] More and more ground glass opacity associated lung adenocarcinoma (GGO-LUAD) have been diagnosed in young patients nowadays. Our study aims to investigate the clinical features and surgical outcomes of young patients with GGO-LUAD. [METHODS] Patients aged ≤ 40 years who were diagnosed as lung adenocarcinom...
clinical features; ground glass opacity; lung adenocarcinoma; prognosis; young patients
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,184,276
Method of venous thromboembolism prophylaxis is not a predictor of pulmonary embolus following elective bariatric surgery: a retrospective cohort study of 135,409 patients.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
Surg Obes Relat Dis
18
12
10.1016/j.soard.2022.08.015
eng
2,022
12
null
2,022
9
5
[BACKGROUND] Patients with obesity are at increased risk of pulmonary embolus (PE), a risk that increases perioperatively and is challenging to manage. [OBJECTIVE] An analysis of the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database was performed to determine predictors of...
Bariatric surgery; Pulmonary embolism; Venous thromboembolism prophylaxis
1.219
113
Surgery
Medicine
2,022
36,184,238
Ultrasound meal accommodation test in critically ill patients with and without feeding intolerance UMAT-ICU.
Clinical nutrition ESPEN
Clin Nutr ESPEN
51
null
10.1016/j.clnesp.2022.07.006
eng
2,022
10
null
2,022
7
20
[BACKGROUND] Gastrointestinal dysfunction (GID) is one of the leading causes of nonavoidable discontinuing or delayed enteral feeding in critically ill patients. The ultrasound meal accommodation test (UMAT) has been used in ambulatory patients to evaluate dyspepsia. The objective of this study was to determine differe...
Enteral nutrition; Feeding intolerance; Ultrasound meal accommodation test
0.685
46
Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Medicine; Nursing
2,022
36,183,601
Identifying pleiotropic genes for major psychiatric disorders with GWAS summary statistics using multivariate adaptive association tests.
Journal of psychiatric research
J Psychiatr Res
155
null
10.1016/j.jpsychires.2022.09.038
eng
2,022
11
null
2,022
9
21
[BACKGROUND] Genome wide association studies (GWAS) have discovered a few of single nucleotide polymorphisms (SNPs) related to major psychiatric disorders. However, it is not completely clear which genes play a pleiotropic role in multiple disorders. The study aimed to identify the pleiotropic genes across five psychia...
GWAS; Multiple adaptive association tests; Pleiotropic; Psychiatric disorders; Summary statistics
1.554
172
Biological Psychiatry; Psychiatry and Mental Health
Medicine; Neuroscience
2,022
36,183,454
Role of human leukocyte antigen in anti-epileptic drugs-induced Stevens-Johnson Syndrome/toxic epidermal necrolysis: A meta-analysis.
Seizure
Seizure
102
null
10.1016/j.seizure.2022.09.011
eng
2,022
11
null
2,022
9
17
[PURPOSE] Antiepileptic drugs (AEDs) are extensively used to manage epilepsy and other comorbidities associated with seizures. Human Leukocyte Antigen (HLA) has a strong association with AED-induced severe cutaneous adverse drug reactions. [OBJECTIVE] We aimed to perform a systematic review and meta-analysis to identif...
Allele; Carbamazepine; Human leukocyte antigen; Phenytoin; Risk; Toxic epidermal necrolysis
0.868
104
Medicine; Neurology; Neurology
Medicine; Neuroscience
2,022
36,183,453
Clinical and electroencephalographic features of epilepsy in patients with triple X syndrome: A case series.
Seizure
Seizure
102
null
10.1016/j.seizure.2022.09.010
eng
2,022
11
null
2,022
9
17
[PURPOSE] Triple X syndrome, is an often undiagnosed chromosomal abnormality with an incidence of 1/1000 females. Main associated disorders are urogenital malformations, premature ovarian failure or primary amenorrhea, gastrointestinal problems, psychiatric disorders and epilepsy. To date, triple X is not related to a ...
Anti-seizure medication (ASM); Focal epilepsy; Levetiracetam (LEV); Triple X syndrome; Valproic acid (VPA)
0.868
104
Medicine; Neurology; Neurology
Medicine; Neuroscience
2,022
36,183,311
Needs assessment of cancer survivors in Alaska.
Cancer causes control : CCC
Cancer Causes Control
33
12
10.1007/s10552-022-01636-0
eng
2,022
12
null
2,022
10
2
[PURPOSE] Little is known about cancer survivors' needs in Alaska. To address this knowledge gap, the Alaska Cancer Partnership conducted a needs assessment survey; our objectives were to identify unmet needs of Alaska's cancer survivors; identify survivor sub-populations that might benefit from targeted interventions ...
Cancer survivors; Cancer survivorship; Needs assessment; Unmet needs
null
null
null
null
null
36,183,207
Use of tracking drugs for the search of intra-hospital adverse reactions: a pharmacovigilance study.
Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria
Farm Hosp
46
3
null
eng
2,022
4
26
2,022
4
26
[OBJECTIVE] To estimate the incidence of potential in-hospital adverse reactions with the use of alert drugs in a general hospital in southern Brazil. Method: Cross-sectional study, carried out in a hospital in southern Brazil. The electronic medical records (TASY®) of patients hospitalized between January and August 2...
null
0.231
28
Pharmacology; Medicine
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,183,096
miR21 deletion in osteocytes has direct and indirect effects on skeletal muscle in a sex-dimorphic manner in mice.
Biology of sex differences
Biol Sex Differ
13
1
10.1186/s13293-022-00465-9
eng
2,022
10
1
2,022
10
1
[BACKGROUND] Osteocytic microRNA21 (miR21) removal alters cytokine production and bone mass by modulating osteoclast and osteoblast differentiation and activity. Removing osteocytic miR21 increases osteoclast/osteoblast numbers and bone mass in male mice, whereas it decreases osteoclasts/osteoblasts without affecting b...
null
1.961
68
Endocrinology; Gender Studies
Biochemistry, Genetics and Molecular Biology; Social Sciences
2,022
36,183,092
Inflammatory aneurysm of ascending aorta and left anterior descending artery.
Journal of cardiothoracic surgery
J Cardiothorac Surg
17
1
10.1186/s13019-022-02006-2
eng
2,022
10
1
2,022
10
1
[BACKGROUND] Inflammatory aortic aneurysms represent less than 5% of ascending aortic aneurysms and are mostly diagnosed intraoperatively. Furthermore, to our knowledge, a case of an accompanying inflammatory LAD aneurysm has not been previously reported. [CASE PRESENTATION] We report an unusual case of a 42-year-old f...
Aortitis; Ascending aorta; Inflammatory aneurysm
0.451
61
Surgery; Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
36,182,812
Vagus nerve stimulation paired with rehabilitation for stroke: Implantation experience from the VNS-REHAB trial.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
J Clin Neurosci
105
null
10.1016/j.jocn.2022.09.013
eng
2,022
11
null
2,022
9
28
[OBJECTIVE] Vagus Nerve Stimulation (VNS) paired with rehabilitation delivered by the Vivistim® Paired VNS™ System was approved by the FDA in 2021 to improve motor deficits in chronic ischemic stroke survivors with moderate to severe arm and hand impairment. Vagus nerve stimulators have previously been implanted in ove...
Chronic stroke; Neuromodulation; Stroke rehabilitation; VNS implantation; Vagus Nerve Stimulation
0.54
104
Medicine; Surgery; Neurology; Neurology; Physiology
Medicine; Neuroscience
2,022
36,182,805
Proxalutamide in patients with AR-positive metastatic breast cancer: Results from an open-label multicentre phase Ib study and biomarker analysis.
European journal of cancer (Oxford, England : 1990)
Eur J Cancer
176
null
10.1016/j.ejca.2022.08.025
eng
2,022
11
null
2,022
9
28
[AIM] Proxalutamide is a novel second-generation non-steroidal androgen receptor (AR) antagonist. This study aimed to evaluate the preliminary efficacy and safety of proxalutamide in patients with AR-positive metastatic breast cancer (AR[+] mBC). [METHODS] In this open-label, dose-expansion, multicentre phase Ib trial,...
Androgen receptor; Androgen receptor antagonist; Biomarker; Efficacy; Metastatic breast cancer; Phase Ib study; Proxalutamide; Safety
2.898
256
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,182,646
The effect of web-based preoperative information on parents of children who are going through elective ambulatory surgery: A systematic review and meta-analysis.
Patient education and counseling
Patient Educ Couns
105
12
10.1016/j.pec.2022.09.006
eng
2,022
12
null
2,022
9
13
[OBJECTIVE] To evaluate the effect of preoperative web-based information to parents of children undergoing elective ambulatory surgery performed with anesthesia. Outcome measures were parental anxiety, knowledge, and satisfaction. [METHOD] The review followed the PRISMA statement. A systematic search of six databases w...
Ambulatory surgery; Parent; Pediatric surgery; Preoperative education; Web-based information
1
168
Medicine
Medicine
2,022
36,182,004
Additional diagnostic value of electron microscopic examination in endomyocardial biopsy in patients with suspected non-ischemic cardiomyopathy.
Journal of cardiology
J Cardiol
81
2
10.1016/j.jjcc.2022.09.012
eng
2,023
2
null
2,022
9
28
[BACKGROUND] Electron microscopy enables a finely detailed analysis of ultra-structural features, and hence, it generally has an added diagnostic value to light microscopy alone. However, no studies have verified the additional diagnostic value of electron microscopic examination in patients with suspected non-ischemic...
Cardiomyopathy; Electron microscopy; Endomyocardial biopsy
0.81
66
Cardiology and Cardiovascular Medicine
Medicine
2,023
36,181,992
The Effect of Stereotactic Body Radiation Therapy for Hepatocellular Cancer on Regional Hepatic Liver Function.
International journal of radiation oncology, biology, physics
Int J Radiat Oncol Biol Phys
115
3
10.1016/j.ijrobp.2022.09.077
eng
2,023
3
1
2,022
9
28
[PURPOSE] To investigate direct radiation dose-related and inflammation-mediated regional hepatic function losses after stereotactic body radiation therapy (SBRT) in patients with hepatocellular carcinoma (HCC) and poor liver function. [METHODS AND MATERIALS] Twenty-four patients with HCC enrolled on an IRB-approved ad...
null
1.992
286
Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy
2,023
36,181,913
Convergent and divergent cognitive impairment of unipolar and bipolar depression: A magnetoencephalography resting-state study.
Journal of affective disorders
J Affect Disord
321
null
10.1016/j.jad.2022.09.126
eng
2,023
1
15
2,022
9
29
[BACKGROUND] Unipolar depression (UD) and bipolar depression (BD) showed convergent and divergent cognitive impairments. Neural oscillations are linked to the foundational cognitive processes. We aimed to investigate the underpinning spectral neuronal power patterns by magnetoencephalography (MEG), which combinates hig...
Bipolar depression; Cognitive impairment; MEG; Magnetoencephalography; Resting-state; Unipolar depression
2.082
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,023
36,180,935
Risk factors for early progression of diffuse low-grade glioma in adults.
Chinese neurosurgical journal
Chin Neurosurg J
8
1
10.1186/s41016-022-00295-z
eng
2,022
10
1
2,022
10
1
[BACKGROUND] To explore the risk factors for early progression of diffuse low-grade glioma in adults. [METHODS] A retrospective analysis of pathologic and clinical data of patients diagnosed with diffuse low-grade gliomas at Southwest Hospital between January 2010 and December 2014. The progression-free survival (PFS) ...
Early progression; Low-grade glioma; Risk factors
0.448
16
Surgery; Neurology; Neurology
Medicine; Neuroscience
2,022
36,180,827
Elevated NT-proBNP levels are associated with CTP ischemic volume and 90-day functional outcomes in acute ischemic stroke: a retrospective cohort study.
BMC cardiovascular disorders
BMC Cardiovasc Disord
22
1
10.1186/s12872-022-02861-w
eng
2,022
9
30
2,022
9
30
[OBJECTIVE] To investigate the impact of N-terminal pro-B-type natriuretic peptide (NT-proBNP) on CTP infarct core volume and poor 90-day functional outcomes in acute ischemic stroke (AIS). [METHODS] A total of 403 hospitalized patients with AIS in the Stroke Center of the First Hospital Affiliated to Soochow Universit...
Acute ischemic stroke; CTP perfusion; N-terminal pro-B-type natriuretic; Outcomes; Treatment decisions
0.601
76
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,180,285
Sulfate-Reducing Bacteria in Patients Undergoing Fixed Orthodontic Treatment.
International dental journal
Int Dent J
73
2
10.1016/j.identj.2022.07.007
eng
2,023
4
null
2,022
9
27
[OBJECTIVES] The oral microbiological environment may be implicated in the corrosion of orthodontic metals. This study aimed to examine the prevalence of sulfate-reducing bacteria (SRB) in orthodontic patients undergoing fixed appliance treatment. [METHODS] Sixty-nine orthodontic and 69 healthy non-orthodontic particip...
Desulfovibrio; Microbial corrosion; Nickel-titanium; Orthodontics; Periodontal disease; Sulfate-reducing bacteria
0.803
81
Dentistry
Dentistry
2,023
36,180,274
Acute Vocal Fold Hemorrhage: Retrospective Analysis in a Voice Unit.
Journal of voice : official journal of the Voice Foundation
J Voice
39
1
10.1016/j.jvoice.2022.07.023
eng
2,025
1
null
2,022
9
28
[OBJECTIVES] To describe our experience in diagnosis, evaluation, management and evolution of adult patients diagnosed with vocal fold hemorrhage (VFH) in the Voice Unit at Universidad Católica Clinical Hospital Santiago, Chile. [STUDY DESIGN] Retrospective chart review. [METHODS] Adult patients diagnosed with VFH betw...
Performing voice; Phonotrauma; Vocal hemorrhage; Vocal injury
0.573
114
LPN and LVN; Otorhinolaryngology; Speech and Hearing
Health Professions; Medicine; Nursing
2,024
36,180,029
Deep Learning Segmentation, Visualization, and Automated 3D Assessment of Ciliary Body in 3D Ultrasound Biomicroscopy Images.
Translational vision science technology
Transl Vis Sci Technol
11
10
10.1167/tvst.11.10.3
eng
2,022
10
3
null
null
null
[PURPOSE] This study aimed to develop a fully automated deep learning ciliary body segmentation and assessment approach in three-dimensional ultrasound biomicroscopy (3D-UBM) images. [METHODS] Each 3D-UBM eye volume was aligned to the optic axis via multiplanar reformatting. Ciliary muscle and processes were manually a...
null
null
null
null
null
null
36,180,020
P21 deficiency exhibits delayed endochondral ossification during fracture healing.
Bone
Bone
165
null
10.1016/j.bone.2022.116572
eng
2,022
12
null
2,022
9
27
[INTRODUCTION] Endochondral ossification is a complex biological phenomenon involving a variety of factors and cells. Cyclin-dependent kinase inhibitor 1 (p21) inhibits cell cycle progression and is affected by external stress. We recently reported that embryonic endochondral ossification is unaffected by endogenous p2...
Endochondral ossification; Fracture healing; Tibia fracture; p21
1.127
230
Endocrinology, Diabetes and Metabolism; Histology; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,179,383
Child abuse and neglect in Brussels during the COVID-19-lockdown.
Child abuse neglect
Child Abuse Negl
134
null
10.1016/j.chiabu.2022.105903
eng
2,022
12
null
2,022
9
22
[BACKGROUND] It is likely that the circumstances during the COVID-19-lockdown in Belgium increased the incidence and prevalence of child abuse and neglect (CAN) due to exacerbated risk factors and new COVID-19-related stressors. However, traditional reporters had less contact with children which could lead to undetecte...
Child abuse; Child neglect; Covid-19; Lockdown; Maltreatment
null
null
null
null
null
36,179,241
Plasma Amino Acid Concentrations in Children With Severe Malaria Are Associated With Mortality and Worse Long-term Kidney and Cognitive Outcomes.
The Journal of infectious diseases
J Infect Dis
226
12
10.1093/infdis/jiac392
eng
2,022
12
13
null
null
null
[BACKGROUND] Global changes in amino acid levels have been described in severe malaria (SM), but the relationship between amino acids and long-term outcomes in SM has not been evaluated. [METHODS] We measured enrollment plasma concentrations of 20 amino acids using high-performance liquid chromatography in 500 Ugandan ...
acute kidney injury; amino acids; cerebral malaria; chronic kidney disease; cognition
2.386
282
Immunology and Allergy; Infectious Diseases
Medicine
2,022
36,178,602
Role of Strauss ECG criteria as predictor of response in patients undergoing cardiac resynchronization therapy.
The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology
Egypt Heart J
74
1
10.1186/s43044-022-00308-3
eng
2,022
9
30
2,022
9
30
[BACKGROUND] Cardiac resynchronization therapy (CRT) is a standard treatment in patients with heart failure; however, approximately 20-40% of recipients of (CRT) do not respond to it based on the current patients' selection criteria. The purpose of this study was to identify the baseline parameters that predict the CRT...
Cardiac resynchronization therapy; Ejection fraction; Electrocardiogram; End-systolic volume; Global circumferential strain; Global longitudinal strain; Left bundle branch block; New York heart association
0.3
19
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,177,917
The mSteps pilot study: Analysis of the distance walked using a novel smartphone application in multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England)
Mult Scler
28
14
10.1177/13524585221124043
eng
2,022
12
null
2,022
9
30
[BACKGROUND] Clinical studies in multiple sclerosis (MS) often require accurate measurement of walking distance. Utilisation of electronic devices could theoretically improve this. Mobile devices have the potential to continuously monitor health by collecting movement data. Popular fitness trackers record steps taken a...
GPS tracking; Wearable technology; indoor tracking; mSteps; multiple sclerosis
null
null
null
null
null
36,177,827
Spinal anaesthesia with clonidine: pain relief and earlier mobilisation after open nephrectomy - a randomised clinical trial.
The Journal of international medical research
J Int Med Res
50
9
10.1177/03000605221126883
eng
2,022
9
null
null
null
null
[OBJECTIVES] Early mobilisation and effective pain management after open nephrectomy for renal cell carcinoma often include epidural analgesia (EDA), requiring an infusion pump and a urinary catheter, thus impeding mobilisation. Spinal anaesthesia (SpA) may be an alternative. This randomised clinical trial evaluated wh...
Spinal anaesthesia; epidural analgesia; length of stay; mobilisation; mobility index; pain score; partial nephrectomy; radical nephrectomy; randomised clinical trial
0.393
74
Biochemistry; Biochemistry; Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,177,800
Prediction of Neonatal Growth Restriction in Fetuses With Gastroschisis by Early Third Trimester Ultrasonography Utilizing Contemporary Birth Weight Percentiles.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
J Ultrasound Med
42
5
10.1002/jum.16108
eng
2,023
5
null
2,022
9
30
[OBJECTIVE] To identify the estimated fetal weight (EFW) formula and threshold for the optimal prediction of fetal growth restriction (FGR) at 26-34 weeks' in fetuses with gastroschisis. [METHODS] Late second and third trimester ultrasound data were used to calculate the EFW utilizing eight different formulas: Hadlock ...
estimated fetal weight; gastroschisis; growth restriction
0.607
108
Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,023
36,177,672
Gender differences in psychosocial function and self-reported health status in late-diagnosed autistic adults: results from the FACE-ASD national cohort.
Psychological medicine
Psychol Med
53
12
10.1017/S0033291722002902
eng
2,023
9
null
2,022
9
30
[BACKGROUND] While adult outcome in autism spectrum disorder (ASD) is generally measured using socially valued roles, it could also be understood in terms of aspects related to health status - an approach that could inform on potential gender differences. [METHODS] We investigated gender differences in two aspects of o...
Autism spectrum disorder; co-occurring health conditions; gender differences; general functioning; quality of life
2.768
251
Applied Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,023
36,177,667
Epithelial PD-L1 expression at tumor front predicts overall survival in a cohort of oral squamous cell carcinomas from Sudan.
Clinical and experimental dental research
Clin Exp Dent Res
8
6
10.1002/cre2.666
eng
2,022
12
null
2,022
9
30
[BACKGROUND] We recently described the tumor immune microenvironment (TIME) in oral squamous cell carcinomas (OSCC) from Sudan by assessing the core of the lesions. However, the invasive tumor front (ITF) is the most active part of OSCC lesions; thus, TIME should also be characterized at the ITF in this patient cohort....
biomarker; invasive tumor front (ITF); oral squamous cell carcinoma (OSCC); overall survival (OS)
0.481
27
Dentistry
Dentistry
2,022
36,177,603
Mortality and re-revision following single-stage and two-stage revision surgery for the management of infected primary knee arthroplasty in England and Wales : evidence from the National Joint Registry.
Bone joint research
Bone Joint Res
11
10
10.1302/2046-3758.1110.BJR-2021-0555.R1
eng
2,022
10
null
null
null
null
[AIMS] We compared the risks of re-revision and mortality between two-stage revision surgery and single-stage revision surgery among patients with infected primary knee arthroplasty. [METHODS] Patients with a periprosthetic joint infection (PJI) of their primary knee arthroplasty, initially revised with a single-stage ...
Anesthesiologists; Infection; Knee; National Joint Registry; Revision arthroplasty; infected knee arthroplasties; infection; knee; periprosthetic joint infection (PJI); primary knee arthroplasties; randomized controlled trial; revision surgery; two-stage revision surgeries
null
null
null
null
null
36,177,431
Assessment of knee and ankle proprioception during the third trimester of pregnancy and postpartum period among primiparous women: An observational longitudinal study.
Journal of education and health promotion
J Educ Health Promot
11
null
10.4103/jehp.jehp_311_22
eng
2,022
null
null
2,022
7
29
[BACKGROUND] Pregnant women experience falls, particularly in the third trimester. In this population, physiological changes, as well as ligament laxity, might influence joint proprioception and do not return to normal during the postpartum period. The prevalence of falls during pregnancy and postpartum periods imposes...
Ankle proprioception; knee proprioception; postpartum period; pregnancy; reposition error
0.411
30
Education; Medicine
Medicine; Social Sciences
2,022
36,177,409
Learning and quality of life in undergraduate nursing students: An exploratory study in Chile during the COVID-19 pandemic.
Journal of education and health promotion
J Educ Health Promot
11
null
10.4103/jehp.jehp_295_22
eng
2,022
null
null
2,022
7
29
[BACKGROUND] Coronavirus disease 2019 (COVID-19) is a global pandemic that has modified all social and, especially, learning instances. The purpose of this study was to determine the perception of final-year nursing students at a university in southern Chile regarding the impact of the pandemic on their learning, and c...
Academic Training; educational techniques; nursing education; pandemics
0.411
30
Education; Medicine
Medicine; Social Sciences
2,022
36,176,557
The effect of neurologic music therapy in patients with cerebral palsy: A systematic narrative review.
Frontiers in neurology
Front Neurol
13
null
10.3389/fneur.2022.852277
eng
2,022
null
null
2,022
9
13
[BACKGROUND] Cerebral palsy (CP) is one of the most common causes of disability in children. It is characterized by impairment in motor function and coordination and difficulties in performing daily life activities. Previous research supports that neurologic music therapy (NMT) was effective in improving motor function...
cerebral palsy; motor; music; music therapy; neurologic music therapy; rehabilitation
0.978
118
Neurology; Neurology
Medicine; Neuroscience
2,022
36,229,832
Combining deep sequencing and conventional molecular approaches reveals broad diversity and distribution of fleas and Bartonella in rodents and shrews from Arctic and Subarctic ecosystems.
Parasites & vectors
Parasit Vectors
15
1
10.1186/s13071-022-05446-w
eng
2,022
10
13
2,022
10
13
[BACKGROUND] Bartonella are intracellular bacteria that are transmitted via animal scratches, bites and hematophagous arthropods. Rodents and their associated fleas play a key role in the maintenance of Bartonella worldwide, with > 22 species identified in rodent hosts. No studies have addressed the occurrence and dive...
Arctic; Bartonella; Canada; Fleas; Rodents; Subarctic; Vector-borne disease; Zoonoses
null
null
null
null
null
36,229,804
Leveraging 13 million responses to the U.S. COVID-19 Trends and Impact Survey to examine vaccine hesitancy, vaccination, and mask wearing, January 2021-February 2022.
BMC public health
BMC Public Health
22
1
10.1186/s12889-022-14286-3
eng
2,022
10
13
2,022
10
13
[BACKGROUND] The urgency of the COVID-19 pandemic called upon the joint efforts from the scientific and private sectors to work together to track vaccine acceptance and prevention behaviors. [METHODS] Our study utilized individual responses to the Delphi Group at Carnegie Mellon University U.S. COVID-19 Trends and Impa...
Big data; COVID-19 vaccine; COVID-19 vaccine hesitancy; Health surveys; Mask wearing behavior; Social media
1.307
211
Public Health, Environmental and Occupational Health
Medicine
2,022
36,229,776
Clinical and prognostic analysis of 42 children with malignant rhabdoid tumor of the kidney: a 7-year retrospective multi-center study.
BMC pediatrics
BMC Pediatr
22
1
10.1186/s12887-022-03643-1
eng
2,022
10
13
2,022
10
13
[OBJECTIVE] To discuss the clinical and prognostic indicators of pediatric malignant rhabdoid tumor of the kidney (MRTK), and to increase the understanding of the occurrence and development of MRTK. [METHODS] From July 2014 to September 2021, all cases were confirmed by postoperative pathological examination. Among the...
Children; Diagnosis and treatment; Malignant rhabdoid tumor of the kidney; Multi-centers; Prognostic analysis
0.742
106
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,229,390
Adjustment of progesterone administration after endometrial transcriptomic analysis does not improve reproductive outcomes in women with adenomyosis.
Reproductive biomedicine online
Reprod Biomed Online
46
1
10.1016/j.rbmo.2022.09.007
eng
2,023
1
null
2,022
9
15
[RESEARCH QUESTION] Do patients with adenomyosis present a dysregulated endometrial receptivity that can be reversed with personalized embryo transfer (PET) by transcriptomic-based progesterone adjustment, improving IVF outcomes? [DESIGN] A multicentre, retrospective, cohort study that transcriptomically analysed the e...
Adenomyosis; IVF outcomes; Progesterone; Receptive endometrium; Transcriptomic analysis
1.214
139
Developmental Biology; Obstetrics and Gynecology; Reproductive Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,229,335
The Impact of Chemotherapy Prescription on Long-Term Survival Outcomes in Early-Stage Invasive Lobular Carcinoma - A Systematic Review and Meta-Analysis.
Clinical breast cancer
Clin Breast Cancer
22
8
10.1016/j.clbc.2022.09.005
eng
2,022
12
null
2,022
9
20
[INTRODUCTION] Invasive lobular carcinoma (ILCs) are typically endocrine responsive breast cancers which respond poorly to chemotherapy. The long-term survival advantage of prescribing chemotherapy in such cases remains unclear. To perform a systematic review and meta-analysis assessing, the impact of prescribing chemo...
Oncological outcomes; Systemic chemotherapy
0.862
85
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,229,242
Biomechanical analysis of odontoid and transverse atlantal ligament in humans with ponticulus posticus variation under different loading conditions: Finite element study.
Injury
Injury
53
12
10.1016/j.injury.2022.10.003
eng
2,022
12
null
2,022
10
6
[PURPOSE] Ponticulus posticus (PP) is a variation of the bone bridge that appears in the first cervical vertebra and through which the vertebral artery passes. Odontoid fractures are common spinal bone fractures in older people. This study aims to investigate the effect of neck movements on the odontoid and transverse ...
Biomechanics; Finite element method; Ponticulus posticus; Transverse ligament
0.698
151
Surgery; Emergency Medicine; Orthopedics and Sports Medicine
Medicine
2,022
36,229,177
Effect of atropine, orthokeratology and combined treatments for myopia control: a 2-year stratified randomised clinical trial.
The British journal of ophthalmology
Br J Ophthalmol
107
12
10.1136/bjo-2022-321272
eng
2,023
11
22
2,023
11
22
[PURPOSE] To investigate the 2-year efficacy of atropine, orthokeratology (ortho-k) and combined treatment on myopia. To explore the factors influencing the efficacy. [METHODS] An age-stratified randomised controlled trial. Children (n=164) aged 8-12 years with spherical equivalent refraction of -1.00 to -6.00 D were s...
Child health (paediatrics); Contact lens; Optics and Refraction
1.862
185
Cellular and Molecular Neuroscience; Ophthalmology; Sensory Systems
Medicine; Neuroscience
2,023
36,228,550
Association of air pollutants and osteoporosis risk: The modifying effect of genetic predisposition.
Environment international
Environ Int
170
null
10.1016/j.envint.2022.107562
eng
2,022
12
null
2,022
10
3
[BACKGROUND] Limited studies have examined the association between air pollutants and osteoporosis incidence; however, the results are conflicting. We aimed to quantify the effects of selected air pollutants on osteoporosis risk and explore the modifying effect of genetic predisposition. [METHODS] A total of 422,955 su...
Additive interaction; Air pollution; Genetic susceptibility; Osteoporosis; Polygenic risk score
3.075
274
Environmental Science
Environmental Science
2,022
36,228,319
Evaluating the Potential for ABO-incompatible Islet Transplantation: Expression of ABH Antigens on Human Pancreata, Isolated Islets, and Embryonic Stem Cell-derived Islets.
Transplantation
Transplantation
107
4
10.1097/TP.0000000000004347
eng
2,023
4
1
2,023
3
31
[BACKGROUND] ABO-incompatible transplantation has improved accessibility of kidney, heart, and liver transplantation. Pancreatic islet transplantation continues to be ABO-matched, yet ABH antigen expression within isolated human islets or novel human embryonic stem cell (hESC)-derived islets remain uncharacterized. [ME...
null
1.371
224
Transplantation
Medicine
2,023
36,228,269
Real-world Evidence of COVID-19 Vaccines Effectiveness in Solid-organ Transplant Recipient Population in Colombia: A Study Nested in the Esperanza Cohort.
Transplantation
Transplantation
107
1
10.1097/TP.0000000000004411
eng
2,023
1
1
2,022
12
8
[BACKGROUND] Solid-organ transplant recipients (SOTRs) have a higher risk of coronavirus disease 2019 (COVID-19) complications and death and a less powerful and lasting response to vaccines and to natural infection. In Colombia, this population was prioritized in the National Vaccination Plan against COVID-19 and recei...
null
1.371
224
Transplantation
Medicine
2,023
36,228,178
Enhancing Administrative Claims Data: Feasibility, Validation and Application of Linking Medicare Claims Data and National Marrow Donor Program Search Data.
JCO clinical cancer informatics
JCO Clin Cancer Inform
6
null
10.1200/CCI.22.00069
eng
2,022
10
null
null
null
null
[PURPOSE] Administrative claims data provide real-world service utilization of acute myeloid leukemia (AML) treatment, but lacks insight into treatment delays or barriers. The National Marrow Donor Program (NMDP)/Be The Match Search (Search) data contains information on donor search, but lacks information on treatment ...
null
1.602
41
Cancer Research; Health Informatics; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,227,963
NSAIDs affect dendritic cell cytokine production.
PloS one
PLoS One
17
10
10.1371/journal.pone.0275906
eng
2,022
null
null
2,022
10
13
[BACKGROUND] Immunotherapy is now considered as the new pillar in treatment of cancer patients. Dendritic cells (DCs) play an essential role in stimulating anti-tumor immune responses, as they are capable of cross-presenting exogenous tumor antigens in MHCI complexes to activate naïve CD8+ T cells. Analgesics, like non...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,227,919
The economic burden of low back pain in KwaZulu-Natal, South Africa: A prevalence-based cost-of-illness analysis from the healthcare provider's perspective.
PloS one
PLoS One
17
10
10.1371/journal.pone.0263204
eng
2,022
null
null
2,022
10
13
[BACKGROUND] Low back pain (LBP) is a multifactorial and the most prevalent musculoskeletal disorder, whose economic burden is of global concern. Evidence suggests that the burden of LBP in increasing and will continue rising with the greatest burden occurring in low-and-middle-income-countries (LMICs). This study soug...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,227,893
Role of fluid-phase complement system regulation in the development of hepatitis C virus-associated glomerulonephritis.
PloS one
PLoS One
17
10
10.1371/journal.pone.0276017
eng
2,022
null
null
2,022
10
13
[OBJECTIVES] It is not known why only some hepatitis C virus (HCV) infected patients develop glomerulonephritis (GN). Therefore, we investigated the role of soluble complement regulators in the development of HCV associated GN. [METHODS] Patients with HCV associated GN who were admitted to our nephrology unit between J...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,227,688
Two-year free of complications during antiviral therapy predicts stable re-compensation in immediate-treatment HBV-related decompensated cirrhosis.
Scandinavian journal of gastroenterology
Scand J Gastroenterol
58
4
10.1080/00365521.2022.2132532
eng
2,023
4
null
2,022
10
13
[BACKGROUND AND AIMS] Disease progression could be altered or even reversed in decompensated patients with HBV-related cirrhosis once they initiate antiviral therapy. However, little is known about the stable re-compensation in these patients. [METHODS] In this retrospective study, HBV-related liver cirrhosis patients ...
Decompensated cirrhosis; Hepatitis B Virus; immediate-treatment; re-compensation
0.669
133
Gastroenterology
Medicine
2,023
36,227,499
Circ_0002111/miR-134-5p/FSTL1 signal axis regulates tumor progression and glycolytic metabolism in papillary thyroid carcinoma cells.
Journal of endocrinological investigation
J Endocrinol Invest
46
4
10.1007/s40618-022-01921-4
eng
2,023
4
null
2,022
10
13
[BACKGROUND] Circular RNAs (circRNAs) have essential roles in the malignant progression of papillary thyroid carcinoma (PTC). Circ_0002111 was reported to facilitate cell proliferation and invasion abilities in PTC. This study was performed to explore the regulatory mechanism of circ_0002111 in PTC progression. [METHOD...
Circ_0002111; FSTL1; Papillary thyroid carcinoma; miR-134-5p
1.067
104
Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,227,433
Hyperuricemia: an unrecognized risk factor for kidney-related sequelae in children with hemolytic uremic syndrome.
Pediatric nephrology (Berlin, Germany)
Pediatr Nephrol
38
5
10.1007/s00467-022-05753-5
eng
2,023
5
null
2,022
10
13
[BACKGROUND] Chronic kidney-related sequelae after STEC-HUS occur in 20-40% of patients. Hyperuricemia (HU) may cause acute and chronic toxicity involving the kidneys. We retrospectively assessed if there was an association between the presence of HU during the acute illness and that of kidney-related sequelae in child...
Chronic kidney disease; Escherichia coli; Hemolytic uremic syndrome; Hyperuricemia; Uric acid
0.785
128
Pediatrics, Perinatology and Child Health; Nephrology
Medicine
2,023
36,227,352
Cannabis containing equivalent concentrations of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) induces less state anxiety than THC-dominant cannabis.
Psychopharmacology
Psychopharmacology (Berl)
239
11
10.1007/s00213-022-06248-9
eng
2,022
11
null
2,022
10
13
[RATIONALE] Delta-9-tetrahydrocannabinol (THC), an active component of cannabis, can cause anxiety in some users during intoxication. Cannabidiol (CBD), another constituent of cannabis, has anxiolytic properties suggesting that cannabis products containing CBD in addition to THC may produce less anxiety than THC-only p...
Anxiety; Cannabidiol; Delta-9-tetrahydrocannabinol; Healthy
1.05
218
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,022
36,227,293
Opportunities and challenges in using instrumental variables to study causal effects in nonrandomized stress and trauma research.
Psychological trauma : theory, research, practice and policy
Psychol Trauma
15
6
10.1037/tra0001370
eng
2,023
9
null
2,022
10
13
[OBJECTIVE] Researchers are often interested in assessing the causal effect of an exposure on an outcome when randomization is not ethical or feasible. Estimating causal effects by controlling for confounders can be unconvincing because important potential confounders remain unmeasured. Study designs leveraging instrum...
null
1.552
86
Clinical Psychology; Social Psychology
Psychology
2,023
36,226,902
Olanzapine/samidorphan combination consistently mitigates weight gain across various subgroups of patients.
CNS spectrums
CNS Spectr
28
4
10.1017/S1092852922000967
eng
2,023
8
null
2,022
10
13
[OBJECTIVE] A combination of olanzapine and the opioid receptor antagonist samidorphan (OLZ/SAM) has been approved in the United States for the treatment of adults with schizophrenia or adults with bipolar I disorder. In a phase 3 study in adults with schizophrenia (ENLIGHTEN-2), OLZ/SAM treatment was associated with s...
Antipsychotic; Lybalvi; body mass index; body weight; clinical trial; outpatients; schizophrenia
0.944
94
Neurology; Psychiatry and Mental Health
Medicine
2,023
36,226,783
Provider and patient sex disparities in opioid prescribing and patient outcomes.
Journal of opioid management
J Opioid Manag
18
5
10.5055/jom.2022.0737
eng
2,022
null
null
null
null
null
[OBJECTIVE] To assess sex disparities in opioid prescribing practices and patient outcomes. [DESIGN] A retrospective cross-sectional study. [SETTING] Thirty-three primary care clinics in an academic health system. [PARTICIPANTS] 2,738 adults prescribed 10+ outpatient opioid prescriptions within 12 months. [MAIN OUTCOME...
null
null
null
null
null
null
36,226,311
Predictive model to identify multiple failure to biological therapy in patients with rheumatoid arthritis.
Therapeutic advances in musculoskeletal disease
Ther Adv Musculoskelet Dis
14
null
10.1177/1759720X221124028
eng
2,022
null
null
2,022
10
6
[BACKGROUND] Despite advances in the treatment of rheumatoid arthritis (RA) and the wide range of therapies available, there is a percentage of patients whose treatment presents a challenge for clinicians due to lack of response to multiple biologic and target-specific disease-modifying antirheumatic drugs (b/tsDMARDs)...
b/tsDMARDs; difficult-to-treat rheumatoid arthritis; refractory rheumatoid arthritis
1.102
54
Orthopedics and Sports Medicine; Rheumatology
Medicine
2,022
36,226,237
YAP Overexpression in Breast Cancer Cells Promotes Angiogenesis through Activating YAP Signaling in Vascular Endothelial Cells.
Analytical cellular pathology (Amsterdam)
Anal Cell Pathol (Amst)
2022
null
10.1155/2022/5942379
eng
2,022
null
null
2,022
10
3
[PURPOSE] The YAP signaling pathway is altered and implicated as oncogenic in human mammary cancers. However, roles of YAP signaling that regulate the breast tumor angiogenesis have remained elusive. Tumor angiogenesis is coordinated by the activation of both cancer cells and vascular endothelial cells. Whether the YAP...
null
0.681
38
Medicine; Pathology and Forensic Medicine; Cancer Research; Cell Biology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,226,025
Dermoscopy of Oral Mucosal Lesions: Experience from a Tertiary Care Center in North India and Review of Literature.
Indian dermatology online journal
Indian Dermatol Online J
13
3
10.4103/idoj.idoj_661_21
eng
2,022
null
null
2,022
5
5
[BACKGROUND] Patients with mucosal lesions form a significant number of routine outpatients presenting to the dermatology department where diagnostic confirmation using histopathological examination of mucosal biopsy is neither feasible nor warranted in every patient. [OBJECTIVE] To study the dermoscopic features of va...
Mucocele; mucoscopy; oral mucosa; oral ulcers; pigmentary disorders; squamous cell carcinoma; vascular lesions
0.25
24
Dermatology; Infectious Diseases; Immunology and Allergy; Microbiology
Medicine
2,022
36,225,873
The association of healthy eating index with periodontitis in National Health and Nutrition Examination Study 2011-2012.
Frontiers in nutrition
Front Nutr
9
null
10.3389/fnut.2022.999620
eng
2,022
null
null
2,022
9
26
[AIM] Periodontitis is a chronic inflammatory disorder caused by periodontopathic bacteria that causes inflammation of the supporting tissues around teeth. Previous studies have found that daily dietary nutritional intake can influence the development of periodontal disease. However, research on the Healthy Eating Inde...
dietary structure; healthy eating index; periodontal disease; periodontitis
0.875
94
Food Science; Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Agricultural and Biological Sciences; Medicine; Nursing
2,022
36,225,799
Case report: Fluoroscopic-assisted closed reduction and minimally invasive femoral capital physeal fracture repair in four calves.
Frontiers in veterinary science
Front Vet Sci
9
null
10.3389/fvets.2022.970220
eng
2,022
null
null
2,022
9
26
[OBJECTIVE] To describe a minimally invasive osteosynthesis (MIO) femoral capital physeal fracture (FCPF) repair technique using multiple smooth Steinmann pins in four calves. [STUDY DESIGN] Case series. [ANIMAL] Four calves ( 60 days of age). [METHODS] Medical records at a single referral hospital were searched for ca...
calves; capital; femur; fluoroscopy; fracture; physeal
0.737
85
Veterinary
Veterinary
2,022
36,225,447
Factors Affecting the Decision Regarding COVID-19 Vaccination in the Saudi Public in the Central Region.
Cureus
Cureus
14
9
10.7759/cureus.28874
eng
2,022
9
null
2,022
9
7
[INTRODUCTION] In response to the disease, multiple companies created coronavirus disease 2019 (COVID-19) vaccinations. These vaccines were developed utilizing a variety of technologies and at an unprecedented rate, leading many people to question their efficacy and safety, as well as what they thought about how well t...
covid-19; hesitancy; myths; vaccination; vaccine acceptance
null
null
null
null
null
36,225,114
Quality of rural colonoscopy outperforms key performance indicators in a multi-centre prospective clinical study.
ANZ journal of surgery
ANZ J Surg
93
3
10.1111/ans.18072
eng
2,023
3
null
2,022
10
12
[BACKGROUND] High-quality colonoscopy is vital for the detection and removal of adenomatous polyps and early diagnosis of colorectal cancer. The aim of this study was to prospectively assess the quality and safety of colonoscopies performed in the non-metropolitan setting. Key performance indicators measured include co...
adenoma detection rate; colonoscopy; colorectal cancer; multicentre study; rural surgery
0.453
89
Surgery; Medicine
Medicine
2,023
36,224,762
Correlations between serum hepatitis B core-related antigen and hepatitis B surface antigen in patients with hepatitis B cirrhosis and a hepatitis B virus-DNA-negative status: a retrospective study.
The Journal of international medical research
J Int Med Res
50
10
10.1177/03000605221130714
eng
2,022
10
null
null
null
null
[OBJECTIVE] This study aimed to examine the correlations between serum hepatitis B core-related antigen (HBcrAg) and hepatitis B surface antigen (HBsAg) titers in patients with hepatitis B cirrhosis and a hepatitis B virus (HBV)-DNA-negative status. [METHODS] We retrospectively analyzed the data and blood samples of pa...
HBV-DNA-negative; Hepatitis B cirrhosis; hepatitis B core-related antigen; hepatitis B surface antigen; liver; serological marker
0.393
74
Biochemistry; Biochemistry; Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,224,639
CRISPR/Cas9-mediated deletion of Interleukin-30 suppresses IGF1 and CXCL5 and boosts SOCS3 reducing prostate cancer growth and mortality.
Journal of hematology oncology
J Hematol Oncol
15
1
10.1186/s13045-022-01357-6
eng
2,022
10
13
2,022
10
13
[BACKGROUND] Metastatic prostate cancer (PC) is a leading cause of cancer death in men worldwide. Targeting of the culprits of disease progression is an unmet need. Interleukin (IL)-30 promotes PC onset and development, but whether it can be a suitable therapeutic target remains to be investigated. Here, we shed light ...
CRISPR/Cas9; CXCL5; IGF1; Interleukin-30; Prostate cancer; Tumor microenvironment
null
null
null
null
null
36,224,524
Treatment outcomes in recurrent versus de novo metastatic pancreatic adenocarcinoma: a real world study.
BMC cancer
BMC Cancer
22
1
10.1186/s12885-022-10130-4
eng
2,022
10
12
2,022
10
12
[BACKGROUND] A majority of patients undergoing curative intent surgery for pancreatic ductal adenocarcinoma (PDAC) will unfortunately develop recurrent disease. Treatment outcomes for patients with metastatic disease remain suboptimal. In this study, we evaluated clinical outcomes of patients with recurrent PDAC who re...
De Novo; Overall survival; Pancreatic ductal adenocarcinoma; Real-world outcomes; Recurrent
1.137
171
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,223,779
NONPERFORATING INTRASCLERAL STABBING FOR SUTURELESS 23G SCLEROTOMY CLOSURE.
Retina (Philadelphia, Pa.)
Retina
43
2
10.1097/IAE.0000000000003648
eng
2,023
2
1
null
null
null
[PURPOSE] The need for suturing leaking sclerotomies have not been eliminated completely in transconjunctival sutureless vitrectomy (TSV). This study aims to describe a novel technique for 23-gauge (G) sclerotomy closure in TSV surgery and discuss its effectiveness. [MATERIALS AND METHODS] Two hundred and thirty cases ...
null
1.214
149
Medicine; Ophthalmology
Medicine
2,023
36,223,285
Baseline 10-2 Visual Field Loss as a Predictor for Future Glaucoma Progression.
Journal of glaucoma
J Glaucoma
32
1
10.1097/IJG.0000000000002138
eng
2,023
1
1
2,022
10
12
[PRCIS] Presence of baseline 10-2 visual field (VF) loss was the strongest predictor of future rate of 24-2 VF loss and development of new 24-2 progression events, suggesting a role for 10-2 VF testing in baseline glaucoma risk analysis. [PURPOSE] The purpose of this study is to examine the relationship between baselin...
null
0.995
105
Ophthalmology
Medicine
2,023
36,223,006
Comparison of magnetic resonance imaging findings in patients with intermittent closed lock and acute closed lock of the temporomandibular joint: a cross-sectional retrospective study.
Oral radiology
Oral Radiol
39
3
10.1007/s11282-022-00659-2
eng
2,023
7
null
2,022
10
12
[OBJECTIVE] This study aimed to estimate the disc status in intermittent closed lock (ICL) and permanent closed lock (CL) temporomandibular disorders (TMDs) to test the hypothesis that the disc morphology and degree of anterior disc displacement affect the outcomes of these disorders. [MATERIALS AND METHODS] All patien...
Acute closed lock; Anterior disc displacement; Disc deformity; Intermittent closed lock; Magnetic resonance imaging; Temporomandibular joint
0.602
28
Dentistry; Radiology, Nuclear Medicine and Imaging
Dentistry; Medicine
2,023
36,222,979
Hepatitis D virus infection in a large cohort of immigrants in southern Italy: a multicenter, prospective study.
Infection
Infection
50
6
10.1007/s15010-022-01938-0
eng
2,022
12
null
2,022
10
12
[BACKGROUND] Since few data are available in the literature on the prevalence of anti-Delta-positive subjects in immigrant populations, the aim of the present study was to evaluate the demographic and virological characteristics of HDV infection in a large cohort of immigrants living in southern Italy. [METHODS] Betwee...
Anti-Delta; HBV infection; HDV infection; Immigrants; Viral hepatitis
1.488
94
Infectious Diseases; Medicine; Microbiology
Medicine
2,022
36,222,835
Helicoverpa armigera preference and performance on three cultivars of short-duration pigeonpea (Cajanus cajan): the importance of whole plant assays.
Pest management science
Pest Manag Sci
79
2
10.1002/ps.7230
eng
2,023
2
null
2,022
10
27
[BACKGROUND] Helicoverpa armigera is a major pest of pigeonpea (Cajanus cajan). Efforts to develop pigeonpea varieties resistant to H. armigera attack have been met with limited success, despite reports of high levels of resistance to H. armigera in wild relatives of pigeonpea and reports of low to moderate levels of r...
antibiosis; antixenosis; bioassay; host-plant resistance; larval performance; oviposition behaviour
null
null
null
null
null