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36,952,532
Multiple sclerosis and COVID-19: A retrospective study in Iran.
PloS one
PLoS One
18
3
10.1371/journal.pone.0283538
eng
2,023
null
null
2,023
3
23
[OBJECTIVES] Previous studies suggested a higher rate of COVID-19 infection in patients with multiple sclerosis than in the general population, and limited studies addressed the impact of COVID-19 and its vaccination in patients with multiple sclerosis in Iran. We decided to investigate the factors associated with COVI...
null
0.839
467
Multidisciplinary
Multidisciplinary
2,023
36,952,302
Comparative evaluation of 90-day patient outcomes and healthcare encounters following extended day surgery urethroplasty.
Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Can Urol Assoc J
17
6
10.5489/cuaj.8219
eng
2,023
6
null
null
null
null
[INTRODUCTION] Most centers have shifted to an extended day surgery (XDS) model for urethroplasty. Our study characterizes outcomes and unplanned healthcare encounters of patients undergoing XDS urethroplasty compared to case-matched inpatient controls. [METHODS] We conducted a retrospective, two-surgeon, single-center...
null
null
null
null
null
null
36,952,136
Under recognition and treatment of lymphedema in head and neck cancer survivors - a database study.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
31
4
10.1007/s00520-023-07698-3
eng
2,023
3
23
2,023
3
23
[PURPOSE] Head and neck cancer (HNC) will be diagnosed in approximately 54,000 Americans in 2022 with more than 11,000 dying as a result. The treatment of HNC often involves aggressive multimodal therapy including surgery, radiotherapy, and systemic therapy. HNC and its treatments are associated with multiple painful a...
Fibrosis; Function; Head and neck cancer; Lymphedema; Physical therapy; Quality of life; Rehabilitation
1.007
143
Oncology; Rehabilitation; Oncology
Medicine; Nursing
2,023
36,952,050
Prophylactic alpha-blockade for prevention of post-operative urinary retention after inguinal hernia repair: a systematic review and meta-analysis.
Hernia : the journal of hernias and abdominal wall surgery
Hernia
27
6
10.1007/s10029-023-02764-5
eng
2,023
12
null
2,023
3
23
[BACKGROUND] The rate of post-operative urinary retention (POUR) in inguinal hernia repairs (IHR) is estimated to be approximately 5.9% to 38% worldwide. Currently, there are minimal studies on the prophylaxis of POUR after IHR. Pre-operative administration of alpha-blockers such as (but not limited to) Tamsulosin, Pra...
Alpha-blockers; Inguinal hernia repair (IHR); Post-operative urinary retention (POUR)
0.972
89
Surgery
Medicine
2,023
36,951,625
Neurological complications of rotavirus infection in children: A systematic review and meta-analysis.
Acta paediatrica (Oslo, Norway : 1992)
Acta Paediatr
112
7
10.1111/apa.16775
eng
2,023
7
null
2,023
3
30
[AIM] To systematically review the clinical features and outcomes of paediatric patients developing neurological complications associated with a rotavirus infection. [METHODS] A systematic literature review and meta-analysis was performed, including articles published from 1984 to 2020. Neurological complications were ...
CwG; cerebellitis; convulsions; encephalitis; gastroenteritis; rotavirus
null
null
null
null
null
36,951,579
Impact of skeletal muscle volume on patients with BCLC stage-B hepatocellular carcinoma undergoing sorafenib therapy.
Cancer medicine
Cancer Med
12
9
10.1002/cam4.5810
eng
2,023
5
null
2,023
3
23
[AIM] Skeletal muscle volume has been reported to be an important factor that determines overall survival (OS) and post-progression survival (PPS) in patients with hepatocellular carcinoma (HCC). However, the impact of skeletal muscle volume on HCC with Barcelona Clinic Liver Cancer (BCLC) stage B (BCLC-B) remains uncl...
BCLC stage-B; hepatocellular carcinoma; skeletal muscle; sorafenib
1.174
95
Oncology; Radiology, Nuclear Medicine and Imaging; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,951,027
Use of Chicken Embryos as an Angiogenesis Model for Central Nervous System Malignant Tumor Research.
Turkish neurosurgery
Turk Neurosurg
33
3
10.5137/1019-5149.JTN.40861-22.3
eng
2,023
null
null
null
null
null
[AIM] To demonstrate the usability of chicken chorioallantoic membrane (CAM) as an angiogenesis model for the development and treatment of malignant tumors of the central nervous system. [MATERIAL AND METHODS] A fresh tumor tissue piece taken from Glioblastoma patients, a malignant tumor of the central nervous system, ...
null
0.309
36
Neurology; Surgery
Medicine
2,023
36,950,813
Clinicopathologic significance of the delta-like ligand 4, vascular endothelial growth factor, and hypoxia-inducible factor-2α in gallbladder cancer.
Journal of pathology and translational medicine
J Pathol Transl Med
57
2
10.4132/jptm.2023.02.01
eng
2,023
3
null
2,023
3
14
[BACKGROUND] Gallbladder cancer (GBC) is usually detected in advanced stages with a low 5-year survival rate. Delta-like ligand 4 (DLL4), vascular endothelial growth factor (VEGF), and hypoxia-inducible factor-2alpha (HIF2α) have been studied for their role in tumorigenesis and potential for therapeutic target, and mul...
DLL4; Gallbladder neoplasms; Targeted therapy; Vascular endothelial growth factor
0.663
39
Histology; Pathology and Forensic Medicine
Medicine
2,023
36,950,802
Long-term follow-up outcomes of laser-treated port wine stain patients: A double-blinded retrospective study.
Journal of cosmetic dermatology
J Cosmet Dermatol
22
8
10.1111/jocd.15727
eng
2,023
8
null
2,023
3
23
[BACKGROUND] Port wine stains (PWS) can be effectively treated with lasers. However, complete clearance is rarely observed, and data from long-term studies are limited. The study aimed to evaluate the efficacy and complications of long-term laser treatment in patients with PWS. [METHODS] We performed a 25-year double-b...
cosmetic outcome; laser treatment; port wine stain
0.707
67
Dermatology
Medicine
2,023
36,950,407
Clinical effects of Chemotherapy combined with Immunotherapy in patients with advanced NSCLC and the effect on their nutritional status and immune function.
Pakistan journal of medical sciences
Pak J Med Sci
39
2
10.12669/pjms.39.2.6365
eng
2,023
null
null
null
null
null
[OBJECTIVES] To evaluate the clinical effects of chemotherapy combined with immunotherapy in patients with advanced non-small-cell lung cancer (NSCLC) and the effect on their nutritional status and immune function. [METHODS] Total 120 patients with advanced NSCLC admitted to Affiliated Hospital of Hebei University from...
Advanced NSCLC; Chemotherapy; Immune function; Immunotherapy; Nutritional status
null
null
null
null
null
36,950,022
Exercise-induced changes in gene expression do not mediate post exertional malaise in Gulf War illness.
Brain, behavior, immunity - health
Brain Behav Immun Health
29
null
10.1016/j.bbih.2023.100612
eng
2,023
5
null
2,023
3
11
[BACKGROUND] Post-exertional malaise (PEM) is considered a characteristic feature of chronic multi-symptom illnesses (CMI) like Gulf War illness (GWI); however, its pathophysiology remains understudied. Previous investigations in other CMI populations (i.e., Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) have repo...
Exercise test; Gulf war; MeSH terms: Gene expression; Mediation analysis; Symptom flare up; Veterans health
null
null
null
null
null
36,949,877
Effectiveness of Noncertified Pharmacist-Led Antimicrobial Stewardship Programs in a Medium-Sized Hospital Without an Infectious Disease Specialist: A Retrospective Pre-Post Study.
Open forum infectious diseases
Open Forum Infect Dis
10
3
10.1093/ofid/ofad116
eng
2,023
3
null
2,023
3
4
[BACKGROUND] Few studies have reported the outcomes of antimicrobial stewardship programs (ASPs) implemented without infectious disease (ID) physician or pharmacist specialists. We implemented interventions that included providing antimicrobial optimization recommendations through a pharmacist-led team using prospectiv...
antibiotic stewardship; antimicrobial cost; antimicrobial stewardship; length of stay; medium-sized hospital
1.36
74
Infectious Diseases; Oncology
Medicine
2,023
36,949,875
Investigator-Determined Categories for Fever of Unknown Origin (FUO) Compared With International Classification of Diseases-10 Classification of Illness: A Systematic Review and Meta-analysis With a Proposal for Revised FUO Classification.
Open forum infectious diseases
Open Forum Infect Dis
10
3
10.1093/ofid/ofad104
eng
2,023
3
null
2,023
2
24
[BACKGROUND] Classifying fever of unknown origin (FUO) into categorical etiologies (ie, infections, noninfectious inflammatory, oncologic, miscellaneous, and undiagnosed disorders) remains unstandardized and subject to discrepancies. As some disease classifications change, a systematic review of studies would help phys...
International Classification of Diseases; fever; fever of unknown origin; pyrexia; pyrexia of unknown origin
1.36
74
Infectious Diseases; Oncology
Medicine
2,023
36,949,835
Yoga as an Escape from Depreciating Mental Health due to COVID 19: A Qualitative study analyzing the factors associated with mental status based on the experiences of geriatric population's participation in an Online program during COVID 19 lockdown in India.
International journal of yoga
Int J Yoga
15
3
10.4103/ijoy.ijoy_121_22
eng
2,022
null
null
2,023
1
16
[INTRODUCTION] The COVID-19 pandemic has left an array of direct physical consequences unevenly on the elderly apart from leaving a wide range of indirect consequences of mental health problems on them. This study aims to understand the effect of a Yoga-Meditation based mobile phone application intervention to reduce t...
DASS; geriatric psychiatry; meditation; mental health; quarantine; yoga
null
null
null
null
null
36,949,827
Magnitude of chronic osteomyelitis and its associated factors in children as diagnosed on X-ray visiting at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia: A cross-sectional study.
SAGE open medicine
SAGE Open Med
11
null
10.1177/20503121231161191
eng
2,023
null
null
2,023
3
17
[OBJECTIVES] To assess the magnitude of chronic osteomyelitis and its associated factors in children at Felege Hiwot Comprehensive Specialized Hospital, Bahir Dar, Ethiopia, in 2022. [METHODS] A hospital-based cross-sectional study was done between April 15, 2022 and August 15, 2022, in children with an age of 18 years...
Children; Ethiopia; chronic osteomyelitis; magnitude; radiographic findings
0.615
41
Medicine
Medicine
2,023
36,949,804
What Is Hemidystonia?
Movement disorders clinical practice
Mov Disord Clin Pract
10
3
10.1002/mdc3.13659
eng
2,023
3
null
2,023
2
3
[BACKGROUND] Hemidystonia is defined as dystonia restricted to one side of the body. It is traditionally believed to result from a lesion in the contralateral hemisphere. [OBJECTIVES] To describe a series of hemidystonia patients without lesions on brain imaging. [METHODS] We searched for individuals with potential hem...
classification; diagnosis; dystonia; hemidystonia
0.731
42
Neurology; Neurology
Medicine; Neuroscience
2,023
36,949,549
No evidence for associations between brood size, gut microbiome diversity and survival in great tit (Parus major) nestlings.
Animal microbiome
Anim Microbiome
5
1
10.1186/s42523-023-00241-z
eng
2,023
3
22
2,023
3
22
[BACKGROUND] The gut microbiome forms at an early stage, yet data on the environmental factors influencing the development of wild avian microbiomes is limited. As the gut microbiome is a vital part of organismal health, it is important to understand how it may connect to host performance. The early studies with wild g...
16S rRNA gene; Avian microbiome; Brood size; Gut microbiome; Parus major
null
null
null
null
null
36,949,450
A physical sign of pathological myopia: myopic scleral pit.
BMC ophthalmology
BMC Ophthalmol
23
1
10.1186/s12886-023-02847-y
eng
2,023
3
22
2,023
3
22
[PURPOSE] Myopic scleral pit (MSP) is a rare physical sign of pathological myopia (PM). The aim of this study was to summarize the clinical characteristics of MSP and analyze its correlation with PM. [METHODS] Eight cases with PM and MSP were enrolled in this study. Comprehensive ophthalmic examinations, including subj...
Myopic scleral pit; Pathological myopia; Physical sign
0.749
67
Medicine; Ophthalmology
Medicine
2,023
36,949,405
Histological endometrial dating: a reliable tool for personalized frozen-thawed embryo transfer in patients with repeated implantation failure in natural cycles.
BMC pregnancy and childbirth
BMC Pregnancy Childbirth
23
1
10.1186/s12884-023-05512-w
eng
2,023
3
22
2,023
3
22
[OBJECTIVE] To evaluate the clinical availability and stability of histological endometrial dating as a tool for personalized frozen-thawed embryo transfer (pFET) in patients with repeated implantation failure (RIF) in natural cycles. [METHODS] A total of 1245 RIF patients were recruited to the present study. All of th...
Histological endometrial dating; Personal embryo transfer; Repeated implantation failure; Window of implantation
1.057
122
Obstetrics and Gynecology
Medicine
2,023
36,949,340
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Psychopharmacology
Psychopharmacology (Berl)
240
5
10.1007/s00213-023-06357-z
eng
2,023
5
null
2,023
3
22
[BACKGROUND] Doxorubicin (DOX)-induced neurotoxicity is widely reported in previous studies. Oxidative stress has been validated as a critical event involved in DOX-induced neurotoxicity. As a selective autophagy adaptor protein, p62 is reported to regulate Keap1-Nrf2-ARE antioxidant pathway in response to oxidative st...
Autophagy; CUR; DOX; Keap1-Nrf2-ARE; Oxidative stress
1.053
218
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,023
36,948,512
Comparative effectiveness and safety of analgesic medicines for adults with acute non-specific low back pain: systematic review and network meta-analysis.
BMJ (Clinical research ed.)
BMJ
380
null
10.1136/bmj-2022-072962
eng
2,023
3
22
2,023
3
22
[OBJECTIVE] To evaluate the comparative effectiveness and safety of analgesic medicines for acute non-specific low back pain. [DESIGN] Systematic review and network meta-analysis. [DATA SOURCES] Medline, PubMed, Embase, CINAHL, CENTRAL, ClinicalTrials.gov, clinicialtrialsregister.eu, and World Health Organization's Int...
null
2.803
519
Medicine
Medicine
2,023
36,948,506
Immune and pathologic responses in patients with localized prostate cancer who received daratumumab (anti-CD38) or edicotinib (CSF-1R inhibitor).
Journal for immunotherapy of cancer
J Immunother Cancer
11
3
10.1136/jitc-2022-006262
eng
2,023
3
null
null
null
null
[BACKGROUND] The prostate tumor microenvironment (TME) is immunosuppressive, with few effector T cells and enrichment of inhibitory immune populations, leading to limited responses to treatments such as immune checkpoint therapies (ICTs). The immune composition of the prostate TME differs across soft tissue and bone, t...
Immunomodulation; Immunotherapy; Prostatic Neoplasms; Tumor Microenvironment
3.728
136
Cancer Research; Immunology; Immunology and Allergy; Molecular Medicine; Oncology; Pharmacology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,948,483
Increased actual sling wear is associated with better early patient-reported and image-based outcomes after shoulder surgery.
Journal of shoulder and elbow surgery
J Shoulder Elbow Surg
32
7
10.1016/j.jse.2023.02.127
eng
2,023
7
null
2,023
3
21
[BACKGROUND] Prior studies have failed to show differences in functional outcomes for patient-reported sling use after rotator cuff repair. Temperature-sensing devices are used to more accurately measure brace adherence. The purposes of this study were to quantify actual sling adherence and its predictors and to establ...
Sling; adherence; compliance; outcomes; pain; radiographic
1.855
178
Medicine; Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,023
36,948,354
KIFC3 regulates progression of hepatocellular carcinoma via EMT and the AKT/mTOR pathway.
Experimental cell research
Exp Cell Res
426
1
10.1016/j.yexcr.2023.113564
eng
2,023
5
1
2,023
3
21
[INTRODUCTION] Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related deaths worldwide. Despite an overall downward trend in cancer mortality, HCC-related mortality continues to increase. KIFC3 is involved in cell division and cancers. However, the role of KIFC3 in HCC has yet to be elucidated. [M...
AKT/mTOR pathway; EMT; Hepatocellular carcinoma; Inhibitor; Kinesin
0.947
210
Cell Biology
Biochemistry, Genetics and Molecular Biology
2,023
36,948,131
PINK1/Parkin pathway-mediated mitophagy by AS-IV to explore the molecular mechanism of muscle cell damage.
Biomedicine pharmacotherapy = Biomedecine pharmacotherapie
Biomed Pharmacother
161
null
10.1016/j.biopha.2023.114533
eng
2,023
5
null
2,023
3
21
[BACKGROUND] Functional disorders of mitochondria are closely related to muscle diseases. Many studies have also shown that oxidative stress can stimulate the production of a large number of reactive oxygen species (ROS), which have various adverse effects on mitochondria and can damage muscle cells. [PURPOSE] In this ...
Astragaloside IV; Mitophagy; Myocyte injury; PINK1/Parkin pathway
null
null
null
null
null
36,948,083
Impact of intravesical administration of tranexamic acid on gross hematuria in the emergency department: A before-and-after study.
The American journal of emergency medicine
Am J Emerg Med
68
null
10.1016/j.ajem.2023.03.020
eng
2,023
6
null
2,023
3
16
[INTRODUCTION] Local applications of tranexamic acid (TXA) have been effective in treating various hemorrhagic conditions. In patients with gross hematuria, the main treatment in the emergency department (ED) is continuous bladder irrigation (CBI). However, CBI has no pharmacological effects except blood clot removal f...
Hematuria; Length of stay; Tranexamic acid
0.858
114
Emergency Medicine; Medicine
Medicine
2,023
36,947,748
Mental health care before and during the COVID-19 pandemic in public healthcare centers of a Chilean municipality.
Medwave
Medwave
23
2
10.5867/medwave.2023.02.2675
eng
2,023
3
22
2,023
3
22
[INTRODUCTION] Globally, the COVID-19 pandemic has affected people's mental health care. This study aims to describe mental health care in the first semester of the COVID-19 pandemic of the year 2020 compared to the first semester of the year 2019 in the public health establishments of the commune of Chillán, Chile. [M...
COVID-19; mental disorders; mental health; pandemic; public health
0.316
19
Issues, Ethics and Legal Aspects; Medicine; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,023
36,947,741
Seroprevalence of severe fever with thrombocytopenia syndrome using specimens from the Korea National Health Nutrition Examination Survey.
PLoS neglected tropical diseases
PLoS Negl Trop Dis
17
3
10.1371/journal.pntd.0011097
eng
2,023
3
null
2,023
3
22
[BACKGROUND] Severe fever with thrombocytopenia syndrome (SFTS) is an acute febrile disease caused by bites from ticks infected with the SFTS virus. In Korea, SFTS patients are observed nationwide, including Jeju Island, but there are currently no data regarding the national prevalence of SFTS, including that of reside...
null
1.258
172
Infectious Diseases; Pharmacology, Toxicology and Pharmaceutics; Public Health, Environmental and Occupational Health
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,947,536
Feeding practices, dietary adequacy, and dietary diversities among caregivers with under-five children: A descriptive cross-section study in Dodoma region, Tanzania.
PloS one
PLoS One
18
3
10.1371/journal.pone.0283036
eng
2,023
null
null
2,023
3
22
[INTRODUCTION] Suboptimal feeding practices among caregivers contribute to nutritional-related health problems in children in low and middle-income countries, such as Tanzania. The continuum of the recommended feeding practices has been an utmost challenge among caregivers during the transition from health facilities t...
null
0.839
467
Multidisciplinary
Multidisciplinary
2,023
36,947,467
Covid-19 Surveillance Testing and Resident Outcomes in Nursing Homes.
The New England journal of medicine
N Engl J Med
388
12
10.1056/NEJMoa2210063
eng
2,023
3
23
null
null
null
[BACKGROUND] Despite widespread adoption of surveillance testing for coronavirus disease 2019 (Covid-19) among staff members in skilled nursing facilities, evidence is limited regarding its relationship with outcomes among facility residents. [METHODS] Using data obtained from 2020 to 2022, we performed a retrospective...
null
20.544
1,231
Medicine
Medicine
2,023
36,947,450
The impact of community-based health insurance on universal health coverage in Ethiopia: a systematic review and meta-analysis.
Global health action
Glob Health Action
16
1
10.1080/16549716.2023.2189764
eng
2,023
12
31
null
null
null
[BACKGROUND] Ideally health insurance aims to provide financial security, promote social inclusion, and ensure equitable access to quality healthcare services for all households. Community-based health insurance has been operating in Ethiopia since 2011. However, its nationwide impact on universal health coverage has n...
Financial risk protection; health service quality; health-related quality of life; healthcare seeking behavior; population coverage
0.896
76
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,023
36,947,314
International primary knee arthroplasty registry review: findings from current reports.
European journal of orthopaedic surgery traumatology : orthopedie traumatologie
Eur J Orthop Surg Traumatol
33
7
10.1007/s00590-023-03521-1
eng
2,023
10
null
2,023
3
22
[INTRODUCTION] International joint registries provide high volumes of information in relation to the performance of total knee arthroplasty on a global scale. Distillation of this data can be challenging, particularly with the establishment of more arthroplasty registries on a yearly basis. We therefore aim to present ...
Knee; Registry; TKA; TKR
null
null
null
null
null
36,947,209
Olaparib in an ovarian cancer patient with end-stage renal disease and hemodialysis.
Cancer chemotherapy and pharmacology
Cancer Chemother Pharmacol
91
4
10.1007/s00280-023-04514-x
eng
2,023
4
null
2,023
3
22
[PURPOSE] For patients with severe renal impairment (CrCl ≤ 30 ml/min) or end-stage renal disease (ESRD), olaparib intake is not recommended as the pharmacokinetics and safety of olaparib have not been evaluated in this patient group. Therefore, this valuable patient group is generally excluded from poly(ADP-ribose) po...
End-stage renal disease; Hemodialysis; Maintenance therapy; Olaparib; Ovarian cancer; PARP inhibitor
0.869
127
Toxicology; Cancer Research; Oncology; Pharmacology; Pharmacology
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,947,046
PhacoTrainer: Deep Learning for Cataract Surgical Videos to Track Surgical Tools.
Translational vision science technology
Transl Vis Sci Technol
12
3
10.1167/tvst.12.3.23
eng
2,023
3
1
null
null
null
[PURPOSE] The purpose of this study was to build a deep-learning model that automatically analyzes cataract surgical videos for the locations of surgical landmarks, and to derive skill-related motion metrics. [METHODS] The locations of the pupil, limbus, and 8 classes of surgical instruments were identified by a 2-step...
null
null
null
null
null
null
36,946,828
Microtomographic, histomorphometric, and molecular features show a normal alveolar bone healing process in iNOS-deficient mice along a compensatory upregulation of eNOS and nNOS isoforms.
Journal of applied oral science : revista FOB
J Appl Oral Sci
31
null
10.1590/1678-7757-2022-0436
eng
2,023
null
null
2,023
3
20
[METHODOLOGY] Inducible nitric oxide synthase (iNOS) is one of the enzymes responsible for the synthesis of nitric oxide (NO), which is an important signaling molecule with effects on blood vessels, leukocytes, and bone cells. However, the role of iNOS in alveolar bone healing remains unclear. This study investigated t...
null
0.688
65
Dentistry; Medicine
Dentistry; Medicine
2,023
36,946,460
Preventive effect of Helicobacter pylori eradication on the coronary heart diseases depending on age and sex with a median follow-up of 51 months.
Helicobacter
Helicobacter
28
4
10.1111/hel.12969
eng
2,023
8
null
2,023
3
22
[BACKGROUND] The association between Helicobacter pylori (HP) infection and coronary heart disease (CHD) is controversial. This study aimed to investigate the effect of H. pylori eradication on CHD, especially in terms of age and sex. [MATERIALS AND METHODS] From May 2003 to March 2022, 4765 subjects with H. pylori inf...
Helicobacter pylori; age; coronary disease; eradication; sex
1.035
94
Gastroenterology; Infectious Diseases; Medicine
Medicine
2,023
36,946,382
Clinical Diagnostic Value of Atypical Glandular Cells in Cervical Cytology: A Single Center Experience From China.
Journal of lower genital tract disease
J Low Genit Tract Dis
27
3
10.1097/LGT.0000000000000730
eng
2,023
7
1
2,023
3
22
[OBJECTIVE] This study aimed to investigate the diagnostic value of atypical glandular cells (AGCs) by analyzing the prevalence and histopathology of AGCs according to cervical cytology. [METHODS] The authors retrospectively reviewed and analyzed the demographic characteristics and histopathological outcomes including ...
null
0.972
56
Medicine; Obstetrics and Gynecology
Medicine
2,023
36,946,250
Strengths and weaknesses in the high-risk baby care network.
Revista da Escola de Enfermagem da U S P
Rev Esc Enferm USP
57
null
10.1590/1980-220X-REEUSP-2022-0150en
eng
2,023
null
null
2,023
3
13
[OBJECTIVE] To characterize the Stork Network in health care for high-risk babies, pointing out its main challenges. [METHOD] questionnaires were applied with those responsible for the babies and with network health professionals. Data were analyzed quantitatively. [RESULTS] statistically relevant variables were: link ...
null
null
null
null
null
null
36,945,452
Prospective Bidirectional Relations Between Depression and Metabolic Health: 30 Year Follow-up from the NHLBI CARDIA Study.
medRxiv : the preprint server for health sciences
medRxiv
null
null
10.1101/2023.03.08.23286983
eng
2,023
3
10
2,023
3
10
[OBJECTIVE] This study investigated prospective bidirectional relationships between depression and metabolic syndrome (MetS), and the moderating effects of race, sex, and health behaviors in a diverse cohort followed for 30 years. [METHODS] Data were analyzed from the NHLBI CARDIA study, a 30 year-prospective study of ...
depression; longitudinal study; metabolic syndrome; race; sex
null
null
null
null
null
36,945,358
Concordance of chest x-ray with chest CT by body mass index.
PeerJ
PeerJ
11
null
10.7717/peerj.15090
eng
2,023
null
null
2,023
3
16
[INTRODUCTION] Patients with suspected thoracic pathology frequently get imaging with conventional radiography or chest x-rays (CXR) and computed tomography (CT). CXR include one or two planar views, compared to the three-dimensional images generated by chest CT. CXR imaging has the advantage of lower costs and lower r...
Body mass index; Chest x-ray; Computed tomography; Diagnostic imaging
0.623
124
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,023
36,944,558
A Pilot Randomized Controlled Trial of Effectiveness of a Psychoeducational Intervention on the Management of Musculoskeletal Chronic Noncancer Pain.
Pain management nursing : official journal of the American Society of Pain Management Nurses
Pain Manag Nurs
24
4
10.1016/j.pmn.2023.01.007
eng
2,023
8
null
2,023
3
21
[AIMS] To investigate the effectiveness of a psychoeducational intervention on pain intensity management in musculoskeletal chronic noncancer pain and to identify relevant variables and preliminary data to allow the design of a randomized controlled trial. [DESIGN] Two arms parallel randomized pilot study. [SUBJECTS AN...
Chronic pain; Pain intensity; Patient education; Quality of life; Self-management
0.494
62
Advanced and Specialized Nursing
Nursing
2,023
36,944,529
Timing of cardiac resynchronization therapy implantation.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Europace
25
5
10.1093/europace/euad059
eng
2,023
5
19
null
null
null
[AIMS] The optimum timing of cardiac resynchronization therapy (CRT) implantation is unknown. We explored long-term outcomes after CRT in relation to the time interval from a first heart failure hospitalization (HFH) to device implantation. [METHODS AND RESULTS] A database covering the population of England (56.3 milli...
Cardiac resynchronization therapy; Heart failure; Heart failure hospitalization; Mortality
null
null
null
null
null
36,944,492
Dual-layered stents reduce cerebral embolism compared with first-generation stents during carotid stenting of high lipid core plaque lesions.
Journal of neurointerventional surgery
J Neurointerv Surg
16
1
10.1136/jnis-2023-020106
eng
2,023
12
19
2,023
12
19
[BACKGROUND] Periprocedural lipid core plaque (LCP) has been detected in carotid arteries assessed by catheter-based near-infrared spectroscopy (NIRS). High LCP is associated with cerebral embolism after carotid artery stenting (CAS) using a first-generation stent. We aimed to evaluate whether dual-layered stents reduc...
Atherosclerosis; Intervention; Stenosis; Stent; Vessel Wall
1.659
90
Medicine; Neurology; Surgery
Medicine
2,023
36,944,411
Characterisation and mobilisation of IncA/C plasmid-mediated antibiotic resistance in Edwardsiella ictaluri.
Journal of global antimicrobial resistance
J Glob Antimicrob Resist
33
null
10.1016/j.jgar.2023.03.005
eng
2,023
6
null
2,023
3
21
[OBJECTIVES] Edwardsiella ictaluri is an important pathogen in farmed raised catfish. Recently, we showed that resistance to tetracycline and florfenicol in the E. ictaluri MS-17-156 strain isolated from channel catfish was facilitated by acquisition of a 135 kb plasmid (named pEIMS-171561). [METHODS] We described the ...
Aquaculture; Catfish; Endogenous microbiota; Multidrug-resistant
0.88
55
Immunology; Immunology and Allergy; Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,023
36,944,164
A Survey to Identify Screen Test Usage by Certified Orthoptists Across the United States of America.
Journal of binocular vision and ocular motility
J Binocul Vis Ocul Motil
73
2
null
eng
2,023
null
null
2,023
3
21
[PURPOSE] To ascertain the use of screen tests for assessing strabismus under binocular viewing conditions by certified orthoptist colleagues around the United States of America. [METHODS] A link to an online survey was distributed to all 440 registered members of the American Association of Certified Orthoptists in ea...
Screen test; strabismus; survey
null
null
null
null
null
36,943,897
Multidirectional corneoconjunctival transposition in the treatment of large keratomalacia in 7 dogs and 5 cats.
Veterinary ophthalmology
Vet Ophthalmol
28
2
10.1111/vop.13086
eng
2,025
3
null
2,023
3
21
[OBJECTIVE] To describe the use of multidirectional corneoconjunctival transposition (CCT) as a surgical treatment for large keratomalacia. [METHOD] A prospective study including dogs and cats initially presenting with keratomalacia larger than 6 × 6 mm and affecting more than half of the corneal thickness. Signalment,...
cat; cornea; dog; graft; keratomalacia
0.568
64
Veterinary
Veterinary
2,024
36,943,830
A retrospective study of risk factors, causative micro-organisms and healthcare resources consumption associated with prosthetic joint infections (PJI) using the Clinical Practice Research Datalink (CPRD) Aurum database.
PloS one
PLoS One
18
3
10.1371/journal.pone.0282709
eng
2,023
null
null
2,023
3
21
[BACKGROUND] Prosthetic joint infection (PJI) is a serious complication after joint replacement surgery and it is associated with risk of mortality and morbidity along with high direct costs. [METHODS] The Clinical Practice Research Datalink (CPRD) data were utilized to quantify PJI incidence after hip or knee replacem...
null
0.839
467
Multidisciplinary
Multidisciplinary
2,023
36,943,769
The development of the normal Schirmer tear test results during the dog's first year of life.
Veterinary ophthalmology
Vet Ophthalmol
26
3
10.1111/vop.13087
eng
2,023
5
null
2,023
3
21
[OBJECTIVE] To evaluate the relationship between lacrimation and age in a homogeneous group of healthy beagle dogs during the first year of life. [MATERIALS AND METHODS] Schirmer tear test I (STT I) was performed at an interval of 12-15 days in both eyes of 16 clinically healthy beagle dogs (eight males and eight femal...
age; canine; lacrimation; puppies; tear production
0.544
64
Veterinary
Veterinary
2,023
36,943,617
Real-Life Data on the Effectiveness and Safety of Cefiderocol in Severely Infected Patients: A Case Series.
Infectious diseases and therapy
Infect Dis Ther
12
4
10.1007/s40121-023-00776-3
eng
2,023
4
null
2,023
3
21
[INTRODUCTION] Real-life data about cefiderocol use to treat extensively drug-resistant bacteria are scarce. We aim to report our early experience in patients with difficult-to-treat infections and limited therapeutic options. [METHODS] Patients treated with cefiderocol from March 2018 to April 2022 in a tertiary-care ...
Acinetobacter baumannii; Cefiderocol; Critically ill patients; Gram-negative bacteria; Multidrug resistance; Pseudomonas aeruginosa
1.351
53
Infectious Diseases; Microbiology
Medicine
2,023
36,943,483
Predictive factors for respiratory failure and in-hospital mortality after surgery for spinal metastasis.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Eur Spine J
32
5
10.1007/s00586-023-07638-z
eng
2,023
5
null
2,023
3
21
[PURPOSE] Spinal metastasis surgeries carry substantial risk of complications. PRF is among complications that significantly increase mortality rate and length of hospital stay. The risk factor of PRF after spinal metastasis surgery has not been investigated. This study aims to identify the predictors of postoperative ...
In-hospital mortality; Postoperative respiratory failure; Preoperative counseling; Prolonged intubation; Spinal metastasis; Unplanned intubation
1.042
173
Orthopedics and Sports Medicine; Surgery
Medicine
2,023
36,943,456
Safety and efficacy of intra-articular injection of platelet-rich plasma for the treatment of ankle osteoarthritis: a systematic review and meta-analysis.
International orthopaedics
Int Orthop
47
8
10.1007/s00264-023-05773-2
eng
2,023
8
null
2,023
3
21
[PURPOSE] To evaluate the safety and efficacy of platelet-rich plasma (PRP) intra-articular injective treatments for ankle osteoarthritis (OA). [METHODS] A systematic literature search was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines in PubMed, Scopus, E...
Ankle osteoarthritis; Arthritis; Intra-articular injection; Meta-analysis; Platelet-rich plasma
0.877
116
Orthopedics and Sports Medicine; Surgery
Medicine
2,023
36,943,303
Detection of antigen Ag85B expression is useful for the diagnosis of tuberculosis, especially for those with an antituberculosis treatment history.
American journal of clinical pathology
Am J Clin Pathol
160
1
10.1093/ajcp/aqad012
eng
2,023
7
5
null
null
null
[OBJECTIVES] The present study used immunohistochemistry (IHC) to detect antigen Ag85B in tissue sections and aimed to evaluate its validity in histopathologic diagnosis of tuberculosis (TB). [METHODS] In total, 204 patients with confirmed TB and 40 other diseases were included in the present study. Ziehl-Neelsen (Z-N)...
diagnosis; immunohistochemistry; treatment efficacy; tuberculosis
0.775
146
Pathology and Forensic Medicine; Medicine
Medicine
2,023
36,943,066
Test-Retest and Inter-Rater Reliability of the 20-Meter Ambulation Test in Patients with Parkinson's Disease.
Journal of rehabilitation medicine
J Rehabil Med
55
null
10.2340/jrm.v55.4381
eng
2,023
3
21
2,023
3
21
[OBJECTIVE] In patients with Parkinson's disease, limited sit-to-stand, walk and turn contribute to decreased independence and quality of life. The 20-meter Ambulation Test (AT20) evaluates walking a total of 20 m, over a 10-m distance, back and forth between 2 chairs, starting and ending in a seated position. The aim ...
null
0.808
117
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Medicine; Sports Science
Health Professions; Medicine
2,023
36,942,801
Feasibility and validity of using healthcare databases to conduct cross-national comparative studies of opioid use, its determinants and consequences.
Pharmacoepidemiology and drug safety
Pharmacoepidemiol Drug Saf
32
9
10.1002/pds.5618
eng
2,023
9
null
2,023
5
3
[PURPOSE] A cross-national comparative (CNC) study about opioid utilization would allow the identification of strategies to improve pain management and mitigate risk. However, little is known about the accessibility and validity of information in healthcare databases internationally. This study aimed to identify the fe...
cross-national comparison; drug utilization research; global opioid utilization research; healthcare databases; prescribed opioids
1.106
113
Pharmacology; Epidemiology
Medicine
2,023
36,942,420
Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function.
Obesity (Silver Spring, Md.)
Obesity (Silver Spring)
31
4
10.1002/oby.23715
eng
2,023
4
null
null
null
null
[OBJECTIVE] The aim of this study was to investigate glucose tolerance, glucagon response, and beta cell function during a 1-year maintenance period with either exercise, the glucagon-like peptide-1 receptor agonist liraglutide, or the combination after diet-induced weight loss. [METHODS] In this randomized placebo-con...
null
1.586
234
Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine; Nutrition and Dietetics
Biochemistry, Genetics and Molecular Biology; Medicine; Nursing
2,023
36,942,397
Relationship Between Coronavirus Disease 2019 Vaccination Rates and Rare But Potentially Fatal Adverse Events: A Regression Discontinuity Analysis of Western Countries.
Journal of Korean medical science
J Korean Med Sci
38
11
10.3346/jkms.2023.38.e94
eng
2,023
3
20
2,023
3
20
[BACKGROUND] Owing to limited experience with the new vaccine platforms, discussion of vaccine safety is inevitable. However, media coverage of adverse events of special interest could influence the vaccination rate; thus, evaluating the outcomes of adverse events of special interest influencing vaccine administration ...
COVID-19; Regression Discontinuity Analysis; SARS-CoV-2
0.78
91
Medicine
Medicine
2,023
36,942,199
A split-mouth randomised controlled trial comparing the clinical effects of MVISTA with chorion membrane or connective tissue graft in multiple gingival recessions.
The Saudi dental journal
Saudi Dent J
35
2
10.1016/j.sdentj.2022.12.011
eng
2,023
2
null
2,023
1
2
[OBJECTIVES] Modified form of VISTA (MVISTA), a novel surgical procedure, aims at comprehensive root coverage that maintains the inner continuity of the periosteum and papilla. This technique incorporates any regenerative graft material within the tunnel. The objective of study is to compare the MVISTA for treating mul...
Chorion membrane; Connective tissue graft; Gingival recession; Phenotype; Root coverage
0.52
41
Dentistry
Dentistry
2,023
36,942,138
Association between maxillofacial fractures and brain injuries in trauma patients: a cross-sectional study in the Kingdom of Saudi Arabia.
The Pan African medical journal
Pan Afr Med J
43
null
10.11604/pamj.2022.43.193.36283
eng
2,022
null
null
2,022
12
15
[INTRODUCTION] trauma is on the rise in the Kingdom of Saudi Arabia (KSA) due to rapid urbanization and motorization, posing increased risks of traumatic maxillofacial and brain injuries. Given the high morbidity and mortality associated with these injuries, this study aimed to measure the prevalence and associated fac...
Maxillofacial trauma; Saudi Arabia; maxillofacial fractures; traumatic brain injury
0.33
53
Medicine
Medicine
2,022
37,004,944
Does sex affect the risk of 30-day all-cause mortality in cardiogenic shock?
International journal of cardiology
Int J Cardiol
381
null
10.1016/j.ijcard.2023.03.061
eng
2,023
6
15
2,023
3
31
[BACKGROUND] Mortality rates following cardiogenic shock (CS) have stagnated on an unacceptably high level. Limited data regarding the prognostic value of sex in patients suffering from CS is available. Therefore, this study aims to investigate the prognostic value of sex in patients with CS. [METHODS] Consecutive pati...
Cardiogenic shock; Mortality; Prognosis; Sex
1.126
155
Cardiology and Cardiovascular Medicine
Medicine
2,023
37,004,747
Autoimmunity and immunodeficiency associated with monoallelic LIG4 mutations via haploinsufficiency.
The Journal of allergy and clinical immunology
J Allergy Clin Immunol
152
2
10.1016/j.jaci.2023.03.022
eng
2,023
8
null
2,023
3
31
[BACKGROUND] Biallelic mutations in LIG4 encoding DNA-ligase 4 cause a rare immunodeficiency syndrome manifesting as infant-onset life-threatening and/or opportunistic infections, skeletal malformations, radiosensitivity and neoplasia. LIG4 is pivotal during DNA repair and during V(D)J recombination as it performs the ...
DNA ligase 4; autosomal dominant; haploinsufficiency; immunodeficiency; inborn errors of immunity; primary immunodeficiency
3.701
350
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,023
37,004,629
A process-based approach to health-related quality of life as a "way of living".
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Qual Life Res
32
9
10.1007/s11136-023-03385-2
eng
2,023
9
null
2,023
4
1
[INTRODUCTION] There is an historical initiative to establish common theoretical ground to support a framework for assessing health-related quality of life (HRQL). Our aim was to add to this effort with an analysis of theoretical/philosophical themes embedded in HRQL questionnaires and patient reports. [METHODS AND RES...
Eudaimonia; Health-related quality of life; Hedonia; Life aspirations; Stoicism; Well-being
1.299
179
Public Health, Environmental and Occupational Health
Medicine
2,023
37,004,166
Paediatric rheumatologists do not score the physician's global assessment of juvenile idiopathic arthritis disease activity in the same way.
Rheumatology (Oxford, England)
Rheumatology (Oxford)
62
10
10.1093/rheumatology/kead151
eng
2,023
10
3
null
null
null
[OBJECTIVES] To assess the heterogeneity in factors affecting physician's global assessment of disease activity (PhGA) and in PhGA scoring of multiple JIA patient's case scenarios. [METHODS] An electronic web-based questionnaire of factors potentially considered in PhGA was sent worldwide to members of PRINTO and the P...
JIA; disease activity; outcome measure
1.721
205
Pharmacology; Rheumatology
Medicine
2,023
37,004,070
Assessment of the distribution of human and material resources for eye health in the public sector in Nampula, Mozambique.
Human resources for health
Hum Resour Health
21
1
10.1186/s12960-023-00812-w
eng
2,023
3
31
2,023
3
31
[BACKGROUND] The unavailability of human and material resources can affect access to eye health services, constituting an obstacle in the fight against avoidable visual impairment. This study aimed to assess the availability and distribution of human and material resources for eye health in the public sector in Nampula...
Allied ophthalmic personnel; Distribution; Equipment; Eye health professionals; Eye health services; Mozambique; Nampula; Ophthalmologist; Optometrist
1.577
89
Public Administration; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,023
37,003,502
Immunological evaluation of a recombinant vaccine delivered with an analogous hyaluronic acid chitosan nanoparticle-hydrogel against Toxoplasma gondii in mice.
Microbial pathogenesis
Microb Pathog
179
null
10.1016/j.micpath.2023.106092
eng
2,023
6
null
2,023
3
30
[BACKGROUND] Toxoplasma gondii (T. gondii) is not only a threat to the public health but it also poses adverse impacts on the livestock industry. This study aimed to develop a recombinant vaccine composed of T. gondii microneme protein 6 (TgMIC6) and T. gondii rhoptry protein 18 (TgROP18). The vaccine was delivered wit...
Chitosan; Hydrogel; Nanoparticle; Toxoplasma gondii; Vaccine
0.753
107
Infectious Diseases; Microbiology
Immunology and Microbiology; Medicine
2,023
37,003,184
Increasing use of newer antiseizure medication during pregnancy: An observational study with special focus on lacosamide.
Seizure
Seizure
107
null
10.1016/j.seizure.2023.02.015
eng
2,023
4
null
2,023
2
20
[INTRODUCTION] Epilepsy is a common neurological disease requiring long-term therapy also during pregnancy. Most studies on pregnancy outcomes in women with epilepsy are based on antiseizure medication (ASM) in monotherapy. However, about 20-30% of epilepsy patients require polytherapy and newer ASMs are an option, whe...
Antiseizure medication; Birth defect; Epilepsy; Lacosamide; Pregnancy outcome; Spontaneous abortion
0.847
104
Medicine; Neurology; Neurology
Medicine; Neuroscience
2,023
37,003,132
Hypoxia-induced UBE2K promotes the malignant progression of HCC.
Pathology, research and practice
Pathol Res Pract
245
null
10.1016/j.prp.2023.154422
eng
2,023
5
null
2,023
3
25
[BACKGROUND] Hypoxia critically drives malignant tumor development and is characteristic of hepatocellular carcinoma (HCC), where HIF-1α plays a crucial role. The ubiquitin-conjugating enzyme E2K (UBE2K) is known to participate in the advancement of several human cancers. However, the role of UBE2K in HCC or whether it...
Cell migration; Cell proliferation; Hepatocellular carcinoma (HCC); Hypoxia; UBE2K
0.677
72
Pathology and Forensic Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
37,002,647
Effect of flowing water on the pharmacokinetic properties of norfloxacin in channel catfish (Ictalurus punctatus) after single-dose oral administration.
Veterinary medicine and science
Vet Med Sci
9
3
10.1002/vms3.1108
eng
2,023
5
null
2,023
3
31
[BACKGROUND] The recirculating aquaculture system (RAS) is a widely used, water-saving and efficient aquaculture model. However, bacterial diseases are common in farmed fish reared at high densities. Although antibiotics effectively treat these diseases, developing efficient methods to increase drug clearance in fish a...
channel catfish; exercise; flowing water; norfloxacin; pharmacokinetics
0.509
30
Veterinary
Veterinary
2,023
37,002,436
Clinical presentation and recurrence of pituitary neuroendocrine tumors: results from a single referral center in Colombia.
Journal of endocrinological investigation
J Endocrinol Invest
46
11
10.1007/s40618-023-02080-w
eng
2,023
11
null
2,023
3
31
[INTRODUCTION] Pituitary neuroendocrine tumors (PitNETs) represent 15-18.2% of all intracranial tumors. Their clinical presentation can range from chronic headache, visual defects, hypopituitarism to hormone excess syndromes. PitNETS are commonly classified as functioning neuroendocrine tumors (F-PitNETs) and non-funct...
Acromegaly; Adrenocorticotropic-secreting pituitary adenoma; Growth hormone-secreting pituitary adenoma; Pituitary neoplasms; Pituitary neuroendocrine tumors; Prolactinoma
1.067
104
Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
37,002,114
Taming the Tiger: Ultra high dose nitroglycerin in managing sympathetic crashing acute pulmonary edema patient.
The American journal of emergency medicine
Am J Emerg Med
67
null
10.1016/j.ajem.2023.03.043
eng
2,023
5
null
2,023
3
24
[INTRODUCTION] Sympathetic Crashing Acute Pulmonary Edema (SCAPE) lies on the end of the acute heart failure syndrome spectrum with pulmonary edema in all lung zones. NTG at lower doses (10-20 μg/min) cause preload reduction, and at higher doses (> 100 μg/min) causes after-load reduction by arterial dilatation. The mai...
Flash pulmonary edema; Hypertensive heart failure; SCAPE; Sympathetic Crashing Acute Pulmonary Edema; Ultra high dose nitroglycerin
0.858
114
Emergency Medicine; Medicine
Medicine
2,023
37,001,393
Correlation between CT imaging and symptom scores in cystic fibrosis associated chronic sinusitis.
American journal of otolaryngology
Am J Otolaryngol
44
4
10.1016/j.amjoto.2023.103858
eng
2,023
null
null
2,023
3
22
[PURPOSE] There are limited guidelines for diagnosing and managing chronic rhinosinusitis (CRS) in the cystic fibrosis (CF) population. While CF patients are known to have significant opacification on paranasal computed tomography (CT), limited evidence suggests that CT findings are not indicative of patients' symptom ...
Chronic rhinosinusitis; Cystic fibrosis; Lund Mackay CT score; Paranasal sinus CT; SNOT-22; Sinus disease; Sinus opacification
null
null
null
null
null
37,001,392
Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study.
Schizophrenia research
Schizophr Res
255
null
10.1016/j.schres.2023.03.020
eng
2,023
5
null
2,023
3
29
[BACKGROUND] Antipsychotic treatment resistance affects up to a third of individuals with schizophrenia, with recent research finding systematic biological differences between antipsychotic resistant and responsive patients. Our aim was to determine whether cognitive impairment at first episode significantly differs be...
Cognition; First episode psychosis; Prospective cohort; Psychosis; Schizophrenia; Treatment resistance
1.374
204
Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience
2,023
37,000,841
The epidemiology of human Taenia solium infections: A systematic review of the distribution in Eastern and Southern Africa.
PLoS neglected tropical diseases
PLoS Negl Trop Dis
17
3
10.1371/journal.pntd.0011042
eng
2,023
3
null
2,023
3
31
[BACKGROUND] Taenia solium is a tapeworm that causes taeniosis in humans and cysticercosis in humans and pigs. Within Eastern and Southern Africa (ESA), information on the presence of human taeniosis and cysticercosis seems scarce. This systematic review aimed to describe the current information available and gaps in t...
null
1.258
172
Infectious Diseases; Pharmacology, Toxicology and Pharmaceutics; Public Health, Environmental and Occupational Health
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
37,000,495
Using Shopping Data to Improve the Diagnosis of Ovarian Cancer: Computational Analysis of a Web-Based Survey.
JMIR cancer
JMIR Cancer
9
null
10.2196/37141
eng
2,023
3
31
2,023
3
31
[BACKGROUND] Shopping data can be analyzed using machine learning techniques to study population health. It is unknown if the use of such methods can successfully investigate prediagnosis purchases linked to self-medication of symptoms of ovarian cancer. [OBJECTIVE] The aims of this study were to gain new domain knowle...
cancer; carcinoma; diagnostic errors; machine learning; nonprescription drugs; oncology; ovarian cancer; ovarian epithelial; ovarian neoplasms; ovary; over-the-counter; pharmaceutical; self-medication; symptom; symptom assessment
0.79
28
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
37,000,386
Cost Per Relapse Avoided for Ozanimod Versus Other Selected Disease-Modifying Therapies for Relapsing-Remitting Multiple Sclerosis in the United States.
Neurology and therapy
Neurol Ther
12
3
10.1007/s40120-023-00463-y
eng
2,023
6
null
2,023
3
31
[INTRODUCTION] This study assessed the cost-effectiveness of ozanimod compared with commonly used disease-modifying therapies (DMTs) for relapsing-remitting multiple sclerosis (RRMS). [METHODS] Annualized relapse rate (ARR) and safety data were obtained from a network meta-analysis (NMA) of clinical trials of RRMS trea...
Cost-effectiveness analysis; Disease-modifying therapies; Ozanimod
1.042
41
Neurology; Neurology
Medicine; Neuroscience
2,023
37,000,240
Clostridium difficile colitis following geriatric hip fracture surgery: incidence, trends, and risk factors from 45,910 patients.
European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Eur J Orthop Surg Traumatol
33
7
10.1007/s00590-023-03523-z
eng
2,023
10
null
2,023
3
31
[PURPOSE] Clostridium difficile colitis is a serious complication in elderly patients undergoing surgery. The objectives of this study were: (1) to use a nationwide sample of patients to report the incidence and timing of C. difficile colitis in geriatric patients who underwent surgery for hip fractures, (2) to identif...
Clostridium difficile colitis; Complications; Geriatrics; Hip fracture; NSQIP
null
null
null
null
null
36,999,953
Racial differences in upper airway collapsibility and loop gain in young adult males.
Sleep
Sleep
46
12
10.1093/sleep/zsad091
eng
2,023
12
11
null
null
null
[STUDY OBJECTIVES] Previous studies reported that the apnea-hypopnea index was similar in young adult Black and White participants. However, whether this similarity reflects an analogous combination of apneas and hypopneas is unknown. Likewise, the physiological mechanisms underlying this similarity has not been explor...
airway collapsibility; loop gain; racial differences
1.717
248
Neurology; Physiology
Medicine
2,023
36,999,931
The baseline comorbidity burden affects survival in elderly patients with acute myeloid leukemia receiving hypomethylating agents: Results from a multicentric clinical study.
Cancer medicine
Cancer Med
12
10
10.1002/cam4.5858
eng
2,023
5
null
2,023
3
31
[BACKGROUND] In older patients with acute myeloid leukemia (AML), the definition of fitness, prognosis, and risk of death represents an open question. [METHODS] In the present study, we tested the impact on survival of disease- and patient-related parameters in a large cohort of elderly AML patients homogeneously assig...
acute myeloid leukemia; elderly; fitness; hypomethylating agents; prognosis
1.174
95
Oncology; Radiology, Nuclear Medicine and Imaging; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,999,817
Post-operative complications after colorectal cancer surgery increased with higher BMI.
Danish medical journal
Dan Med J
70
4
null
eng
2,023
3
27
2,023
3
27
[INTRODUCTION] Because of conflicting evidence regarding overweight and post-operative complications, this study focused on post-operative complications and death within 30 and 90 days after curatively intended surgery for colorectal cancer and its association with BMI. [METHODS] The study included all patients who had...
null
0.425
59
Medicine
Medicine
2,023
36,999,794
Effect of body habitus on surgical outcomes following bilateral axillo-breast approach robotic thyroidectomy: a retrospective cohort study.
International journal of surgery (London, England)
Int J Surg
109
5
10.1097/JS9.0000000000000279
eng
2,023
5
1
2,023
5
1
[INTRODUCTION] BMI has been shown to predict perioperative outcomes in patients undergoing surgery. Most studies assessing the role of body habitus in thyroid surgery have focused on open surgery, with few studies assessing patients undergoing robotic surgery. The present study evaluated the effects of BMI on surgical ...
null
2.895
99
Medicine; Surgery
Medicine
2,023
36,999,555
YWHAE loss of function causes a rare neurodevelopmental disease with brain abnormalities in human and mouse.
Genetics in medicine : official journal of the American College of Medical Genetics
Genet Med
25
7
10.1016/j.gim.2023.100835
eng
2,023
7
null
2,023
3
28
[PURPOSE] Miller-Dieker syndrome is caused by a multiple gene deletion, including PAFAH1B1 and YWHAE. Although deletion of PAFAH1B1 causes lissencephaly unambiguously, deletion of YWHAE alone has not clearly been linked to a human disorder. [METHODS] Cases with YWHAE variants were collected through international data s...
14-3-3; Brain abnormalities; Miller-Dieker syndrome; Neurodevelopmental disorders; YWHAE
2.697
167
Genetics; Medicine
Medicine
2,023
36,999,462
Correlation between expression of Lin28B and C-myc in patients with laryngeal squamous cell carcinoma and clinicopathological features and prognosis.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Zhong Nan Da Xue Xue Bao Yi Xue Ban
48
2
10.11817/j.issn.1672-7347.2023.220421
eng
2,023
2
28
null
null
null
[OBJECTIVES] Laryngeal squamous cell carcinoma (LSCC) is a common malignant tumor of head and neck. Screening of target genes for malignant tumor therapy is one of the focuses of cancer research, with proto-oncogene and tumor suppressor gene as the breakthrough. It has become an urgent need to find the target gene rela...
C-myc; Lin28B; clinicopathological features; laryngeal squamous cell carcinoma; prognosis
null
null
null
null
null
36,999,451
Quality of life in mothers of children with psoriasis.
Journal of cosmetic dermatology
J Cosmet Dermatol
22
9
10.1111/jocd.15737
eng
2,023
9
null
2,023
3
31
[BACKGROUND] Patients' and their mothers' quality of life is severely affected by childhood psoriasis. Almost all children have a chronic illness that lasts until adulthood, which puts them at risk for lifelong difficulties like stigma, psychiatric comorbidity, and suicide. [OBJECTIVE] Evaluation of the effects of chil...
Family Dermatology Life Quality Index (FDLQI); childhood psoriasis; quality of life (QoL)
0.707
67
Dermatology
Medicine
2,023
36,999,263
Depression Symptoms and Inflammation in Chronic Functional Constipation Patients.
Acta medica Indonesiana
Acta Med Indones
55
1
null
eng
2,023
1
null
null
null
null
[BACKGROUND] Inflammation in chronic functional constipation (CFC) occurs systemically and has association with depressive symptoms. Biomarkers of inflammation can be assessed by the neutrophil to lymphocyte ratio and platelet to lymphocyte ratio. These inflammation biomarkers are stable, cheap, and widely available. T...
Chronic functional constipation; depressive symptoms; inflammation; lymphocyte to neutrophil ratio; platelet to lymphocyte ratio
null
null
null
null
null
36,999,211
Risk-reducing salpingo-oophorectomy for Japanese women with hereditary breast and ovarian cancer: a single-institution 10-year experience.
Japanese journal of clinical oncology
Jpn J Clin Oncol
53
6
10.1093/jjco/hyad020
eng
2,023
6
1
null
null
null
[BACKGROUND] For women diagnosed with hereditary breast and ovarian cancer, the clinical guidelines recommend risk-reducing salpingo-oophorectomy at age 35-40 years or after completion of childbearing. However, there is limited information regarding the current status of risk-reducing salpingo-oophorectomy in Japan. [M...
BRCA; ovarian cancer; risk-reducing salpingo-oophorectomy (RRSO); surveillance
0.612
98
Medicine; Radiology, Nuclear Medicine and Imaging; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,999,015
Design of a multi-epitopic vaccine against Epstein-Barr virus via computer-based methods.
Frontiers in immunology
Front Immunol
14
null
10.3389/fimmu.2023.1115345
eng
2,023
null
null
2,023
3
14
[BACKGROUND] Scientific findings have shown that Epstein-Barr virus (EBV) plays a key role in the development of some tumor diseases. Therefore, this study intends to take a practical step in controlling the pathogenicity of this virus by designing an effective vaccine based on the virus Capsid Envelope and Epstein-Bar...
EBV; adjuvant; cellular immunity; humoral immunity; multi-epitope vaccine; structural proteins
1.868
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,023
36,998,584
Update on neuromonitoring procedures applied during surgery of the spine - observational study.
Reumatologia
Reumatologia
61
1
10.5114/reum/160209
eng
2,023
null
null
2,023
3
8
[INTRODUCTION] Motor evoked potentials (MEPs) are currently considered as a more useful method for neurophysiological intraoperative monitoring than somatosensory evoked potentials in cases of surgery applied to patients with adolescent idiopathic scoliosis. The non-invasive approach is preferred to modify MEP recordin...
health care and safety management; neuromonitoring; spinal cord neural transmission; spine surgery
0.379
30
Immunology and Allergy; Rheumatology; Immunology
Immunology and Microbiology; Medicine
2,023
36,998,481
Investigation of risk factors associated with impaired glucose regulation: Using the momentum equation to assess the impact of risk factors on community residents.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
14
null
10.3389/fendo.2023.1145847
eng
2,023
null
null
2,023
3
14
[OBJECTIVE] To identify risk factors for impaired glucose regulation (IGR) and assess their impact on community residents, this study used a questionnaire to conduct cross-sectional surveys and analysis. [METHODS] Overall, 774 residents of an urban community in northern China (Jian city) participated in this study. Tra...
general population; hypertension; impaired glucose regulation; risk factors; type 2 diabetes mellitus
1.24
138
Endocrinology, Diabetes and Metabolism
Medicine
2,023
36,998,448
Scoring model to predict postoperative neurological deterioration in spinal schwannoma.
Frontiers in oncology
Front Oncol
13
null
10.3389/fonc.2023.1086299
eng
2,023
null
null
2,023
3
14
[BACKGROUND] Spinal schwannomas (SSs) are benign tumors affecting the nerve sheath, accounting for 25% of spinal nerve root tumors. Surgery represents the mainstay of treatment for SS patients. Following surgery, approximately 30% of patients experienced developed new or worsening neurological deterioration, which prob...
functional outcome; prognosis; scoring model; spinal schwannoma; spinal surgery
1.066
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,998,318
Contribution of clinical information to the predictive performance of plasma β-amyloid levels for amyloid positron emission tomography positivity.
Frontiers in aging neuroscience
Front Aging Neurosci
15
null
10.3389/fnagi.2023.1126799
eng
2,023
null
null
2,023
3
14
[BACKGROUND] Early detection of β-amyloid (Aβ) accumulation, a major biomarker for Alzheimer's disease (AD), has become important. As fluid biomarkers, the accuracy of cerebrospinal fluid (CSF) Aβ for predicting Aβ deposition on positron emission tomography (PET) has been extensively studied, and the development of pla...
apolipoprotein E; cerebrospinal fluid; plasma; positron emission tomography
1.173
135
Aging; Cognitive Neuroscience
Biochemistry, Genetics and Molecular Biology; Neuroscience
2,023
36,998,289
Effectiveness of Fortified Garlic Extract Oral Capsules as Adjuvant Therapy in Hospitalized Patients with Coronavirus Disease 2019: A Triple-Blind Randomized Controlled Clinical Trial.
Current therapeutic research, clinical and experimental
Curr Ther Res Clin Exp
98
null
10.1016/j.curtheres.2023.100699
eng
2,023
null
null
2,023
3
14
[BACKGROUND] Herbal medicines have been extensively used to treat coronavirus disease 2019 (COVID-19). Garlic, known to exert antiviral and anti-inflammatory effects, can be coadministered with standard treatments to combat COVID-19. [OBJECTIVES] The aim of the study was to evaluate the efficacy and safety profile of G...
2725; COVID-19; SARS-CoV-2; diallyl polysulfides; garlic extract; noncritically ill
null
null
null
null
null
36,998,284
Comparison of anthropometric parameters and laboratory test results before and after the COVID-19 outbreak among Chinese children aged 3-18 years.
Frontiers in public health
Front Public Health
11
null
10.3389/fpubh.2023.1048087
eng
2,023
null
null
2,023
3
14
[OBJECTIVE] To compare the physiological health of Chinese children around the COVID-19 lockdown. [METHODS] We extracted data on children's anthropometric and laboratory parameters from May to November in both 2019 and 2020 from the Health Checkup Center, Children's Hospital, Zhejiang University School of Medicine, Han...
COVID-19 lockdown; children; lipid metabolism; obesity; vitamin D deficiency
0.895
119
Public Health, Environmental and Occupational Health
Medicine
2,023
36,998,075
Menstrual health and hygiene among Juang women: a particularly vulnerable tribal group in Odisha, India.
Reproductive health
Reprod Health
20
1
10.1186/s12978-023-01603-1
eng
2,023
3
30
2,023
3
30
[BACKGROUND] Menstruation is a normal biological process that all women go through, yet it is shrouded in secrecy, taboos, and even stigma in many societies. Studies have shown that women from socially disadvantaged groups are more likely to have preventable reproductive health issues and have less understanding of hyg...
India; Menstrual hygiene practices; Tribal women
1.083
84
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,023
36,998,054
Frequency and correlates of lifetime suicidal ideation and suicide attempts among consecutively hospitalized youth with anorexia nervosa and bulimia nervosa: results from a retrospective chart review.
Borderline personality disorder and emotion dysregulation
Borderline Personal Disord Emot Dysregul
10
1
10.1186/s40479-023-00216-1
eng
2,023
3
31
2,023
3
31
[BACKGROUND] Youth with eating disorders (EDs) face an increased risk of a premature suicide death. Precursors of completed suicide are suicidal ideation and suicide attempts, which need to be well understood to prevent suicide. However, epidemiological data on the lifetime prevalence and clinical correlates of suicida...
Anorexia nervosa; Bulimia nervosa; Eating disorder; Inpatients; Suicidal ideation; Suicidality; Suicide attempt; Youth
1.373
37
Clinical Psychology; Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience; Psychology
2,023
36,997,856
A clinical frailty scale obtained from MDT discussion performs poorly in assessing frailty in haemodialysis recipients.
BMC nephrology
BMC Nephrol
24
1
10.1186/s12882-023-03126-0
eng
2,023
3
30
2,023
3
30
[BACKGROUND] The Clinical Frailty Scale (CFS) is a commonly utilised frailty screening tool that has been associated with hospitalisation and mortality in haemodialysis recipients, but is subject to heterogenous methodologies including subjective clinician opinion. The aims of this study were to (i) examine the accurac...
Clinical Frailty Scale; Frailty; Haemodialysis; Hospitalisation; Mortality
0.697
83
Nephrology
Medicine
2,023
36,997,793
Relationship Between Oral Temperature and Bacteremia in Hospitalized Patients.
Journal of general internal medicine
J Gen Intern Med
38
12
10.1007/s11606-023-08168-6
eng
2,023
9
null
2,023
3
30
[BACKGROUND] Early recognition and treatment of bacteremia can be lifesaving. Fever is a well-known marker of bacteremia, but the predictive value of temperature has not been fully explored. [OBJECTIVE] To describe temperature as a predictor of bacteremia and other infections. [DESIGN] Retrospective review of electroni...
bacteremia; blood culture; fever; sepsis; temperature
1.732
224
Internal Medicine
Medicine
2,023
36,997,474
Reducing touching eyes, nose and mouth ('T-zone') to reduce the spread of infectious disease: A prospective study of motivational, volitional and non-reflective predictors.
British journal of health psychology
Br J Health Psychol
28
4
10.1111/bjhp.12660
eng
2,023
11
null
2,023
3
30
[BACKGROUND] The route into the body for many pathogens is through the eyes, nose and mouth (i.e., the 'T-zone') via inhalation or fomite-based transfer during face touching. It is important to understand factors that are associated with touching the T-zone to inform preventive strategies. [PURPOSE] To identify theory-...
COVID-19; T-zone; automaticity; face touching; health action process approach; infection control
1.992
110
Applied Psychology; Medicine
Medicine; Psychology
2,023
36,997,363
Diagnostic accuracy for hemoperitoneum, influence on prehospital times and time-to-definitive treatment of prehospital FAST: A systematic review and individual participant data meta-analysis.
Injury
Injury
null
null
10.1016/j.injury.2023.03.024
eng
2,023
3
20
2,023
3
20
[BACKGROUND] Focused assessment sonography for trauma (FAST) performed in the prehospital setting may improve trauma care by influencing treatment decisions and reducing time to definitive care, but its accuracy and benefits remain uncertain. This systematic review evaluated the diagnostic accuracy of prehospital FAST ...
Abdominal injuries; Emergency medical services; Focused assessment with sonography for trauma; Humans; Nonpenetrating; Wounds
0.728
151
Emergency Medicine; Surgery; Orthopedics and Sports Medicine
Medicine
2,023
36,996,771
Interleukin-33 and Soluble ST2 Levels in Infants with Hypoxic-Ischemic Encephalopathy.
Neonatology
Neonatology
120
3
10.1159/000529679
eng
2,023
null
null
2,023
3
30
[INTRODUCTION] Interleukin (IL)-33 and its receptor ST2L play key roles in the IL-33/ST2 signaling pathway. Soluble ST2 (sST2) inhibits the proper function of IL-33. sST2 levels are increased in patients with several neurological diseases, but in infants with hypoxic-ischemic encephalopathy (HIE), IL-33 and sST2 levels...
Asphyxia; Hypoxic-ischemic encephalopathy; Interleukin-33; Soluble ST2
0.874
101
Pediatrics, Perinatology and Child Health; Developmental Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,996,685
Food addiction is strongly associated with type 2 diabetes.
Clinical nutrition (Edinburgh, Scotland)
Clin Nutr
42
5
10.1016/j.clnu.2023.03.014
eng
2,023
5
null
2,023
3
20
[BACKGROUND AND AIMS] Individuals can develop an addiction-like attraction towards highly processed foods, which has led to the conceptualization of food addiction, a phenotype linked to obesity. In this study, we investigated whether food addiction is associated with type 2 diabetes (T2D). [METHODS] 1699 adults from t...
Epidemiology; Food addiction; General populations; Mental disorders; Obesity; Type 2 diabetes
1.893
183
Critical Care and Intensive Care Medicine; Nutrition and Dietetics
Medicine; Nursing
2,023
36,996,575
Investigating the robustness of the AlignRT InBore™ co-calibration process and determining the overall tracking errors.
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Phys Med
108
null
10.1016/j.ejmp.2023.102567
eng
2,023
4
null
2,023
3
28
[OBJECTIVE] To determine the overall tracking errors inherent to the co-calibration procedure of AlignRT InBore™'s (Vision RT Ltd., London, UK) ceiling-mounted and ring-mounted cameras. [METHODS] Extrinsic calibration errors related to the mismatch between ceiling and InBore cameras' isocentres and treatment isocentre ...
Closed-bore linacs; Co-calibration; MV calibration; SGRT
0.943
71
Biophysics; Medicine; Physics and Astronomy; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy
2,023