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37,025,415 | Lipocalin 2 - mutation screen and serum levels in patients with anorexia nervosa or obesity and in lean individuals. | Frontiers in endocrinology | Front Endocrinol (Lausanne) | 14 | null | 10.3389/fendo.2023.1137308 | eng | 2,023 | null | null | 2,023 | 3 | 21 | [CONTEXT] The bone-derived adipokine lipocalin-2 is relevant for body weight regulation by stimulating the leptin-melanocortin pathway. [OBJECTIVE] We aimed to (i) detect variants in the lipocalin-2 gene (LCN2) which are relevant for body weight regulation and/or anorexia nervosa (AN); (ii) describe and characterize th... | Energy homeostasis; GWAS; bone marrow; lean body mass (LBM); secondary structure of protein | 1.24 | 138 | Endocrinology, Diabetes and Metabolism | Medicine | 2,023 |
37,025,411 | Impact of COVID-19 during pregnancy on placental pathology, maternal and neonatal outcome - A cross-sectional study on anemic term pregnant women from a tertiary care hospital in southern India. | Frontiers in endocrinology | Front Endocrinol (Lausanne) | 14 | null | 10.3389/fendo.2023.1092104 | eng | 2,023 | null | null | 2,023 | 3 | 21 | [BACKGROUND] SARS-CoV-2 infection during pregnancy may cause adverse maternal, neonatal and placental outcomes. While tissue hypoxia is often reported in COVID-19 patients, pregnant women with anemia are suspected to be more prone to placental hypoxia-related injuries. [METHODS] This hospital-based cross-sectional stud... | COVID-19; SARS-CoV-2; anemia; cord blood; placenta; pregnancy | 1.24 | 138 | Endocrinology, Diabetes and Metabolism | Medicine | 2,023 |
37,025,260 | A transcriptomics approach to expand therapeutic options and optimize clinical trials in oncology. | Therapeutic advances in medical oncology | Ther Adv Med Oncol | 15 | null | 10.1177/17588359231156382 | eng | 2,023 | null | null | 2,023 | 3 | 31 | [BACKGROUND] The current model of clinical drug development in oncology displays major limitations due to a high attrition rate in patient enrollment in early phase trials and a high failure rate of drugs in phase III studies. [OBJECTIVE] Integrating transcriptomics for selection of patients has the potential to achiev... | analogous normal tissue biopsies; clinical trials; oncology; transcriptomics; tumor biopsies | 1.529 | 74 | Oncology | Medicine | 2,023 |
37,025,031 | Utility of CT colonography and/or PET-CT preoperatively in obstructing left-sided colorectal cancers - a systematic review. | ANZ journal of surgery | ANZ J Surg | 93 | 6 | 10.1111/ans.18450 | eng | 2,023 | 6 | null | 2,023 | 4 | 6 | [PURPOSE] 15-20% of patients present with near obstructing left-sided colorectal cancer. CT colonography (CTC) or PET-CT has been used to detect synchronous lesions, which may alter preoperative planning of colonic resection. We aim to synthesize the usefulness of CT colonography and/or PET-CT in detecting synchronous ... | CT colonography; PET-CT; carcinoma; colorectal; obstruction; outcomes | 0.453 | 89 | Surgery; Medicine | Medicine | 2,023 |
37,024,851 | CYP2C19 loss-of-function is associated with increased risk of hypertension in a Hakka population: a case-control study. | BMC cardiovascular disorders | BMC Cardiovasc Disord | 23 | 1 | 10.1186/s12872-023-03207-w | eng | 2,023 | 4 | 6 | 2,023 | 4 | 6 | [BACKGROUND] Genetic factors have a certain proportion in the risk factors of hypertension. The purpose was to investigate the relationship of cytochrome P450 2C19 (CYP2C19) polymorphisms with hypertension in Hakka population. [METHODS] The study included 1,872 hypertensive patients and 1,110 controls. The genotypes of... | CYP2C19; Hakka; Hypertension; Polymorphism | 0.646 | 76 | Cardiology and Cardiovascular Medicine | Medicine | 2,023 |
37,024,796 | Elemental profiles in distant tissues during tumor progression. | BMC cancer | BMC Cancer | 23 | 1 | 10.1186/s12885-023-10782-w | eng | 2,023 | 4 | 6 | 2,023 | 4 | 6 | [BACKGROUND] Essential elements have functions in tumor progression by promoting protumoral cellular processes, such as proliferation, and migration, among others. Obtaining an understanding of how these elements relate to tumor progression processes is of great importance for research. Elemental profile studies in dis... | Elemental distribution; Essential mineral elements; Lewis lung carcinoma; SR-XRF; Tumor progression | 1.087 | 171 | Cancer Research; Genetics; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,023 |
37,024,792 | Gonadal transcriptomes reveal sex-biased expression genes associated with sex determination and differentiation in red-tail catfish (Hemibagrus wyckioides). | BMC genomics | BMC Genomics | 24 | 1 | 10.1186/s12864-023-09264-x | eng | 2,023 | 4 | 6 | 2,023 | 4 | 6 | [BACKGROUND] Red-tail catfish (Hemibagrus wyckioides) is an important commercially farmed catfish in southern China. Males of red-tail catfish grow faster than females, suggesting that all-male catfish will produce more significant economic benefits in aquaculture practice. However, little research has been reported on... | Gonadal transcriptome; Hemibagrus wyckioides; RNA-Seq; Sex determination; Sex differentiation | 1.047 | 208 | Biotechnology; Genetics | Biochemistry, Genetics and Molecular Biology | 2,023 |
37,024,758 | Implementing Enhanced Perioperative Care in Emergency General Surgery: A Prospective Multicenter Observational Study. | World journal of surgery | World J Surg | 47 | 6 | 10.1007/s00268-023-06984-9 | eng | 2,023 | 6 | null | 2,023 | 4 | 6 | [INTRODUCTION] ERAS pathway has been proposed as the standard of care in elective abdominal surgery. Guidelines on ERAS in emergency surgery have been recently published; however, few evidences are still available in the literature. The aim of this study was to evaluate the feasibility of an enhanced recovery protocol ... | null | 0.772 | 176 | Surgery | Medicine | 2,023 |
37,024,401 | Reality of drug-induced erythema multiforme: A French pharmacovigilance study. | Therapie | Therapie | 78 | 6 | 10.1016/j.therap.2023.03.004 | eng | 2,023 | null | null | 2,023 | 3 | 10 | [BACKGROUND] Since the 2002 SCAR study, erythema multiforme (EM), a post-infectious disease, has been distinguished from Stevens-Johnson syndrome (SJS), drug-induced. Nevertheless, EM cases are still reported in the French pharmacovigilance database (FPDB). [OBJECTIVES] To describe EM reported in the FPDB and to compar... | Dermatology; Drug reactions; Erythema multiforme | null | null | null | null | null |
37,024,084 | Endoscopic Transorbital Approach for the Management of Spheno-Orbital Meningiomas: Literature Review and Preliminary Experience. | World neurosurgery | World Neurosurg | 176 | null | 10.1016/j.wneu.2023.03.126 | eng | 2,023 | 8 | null | 2,023 | 4 | 5 | [OBJECTIVE] The endoscopic transorbital approach (ETOA) is a minimally invasive approach that could be particularly appropriate for management of spheno-orbital meningiomas. The aim of this study was to perform a systematic review of the literature on the management of spheno-orbital meningiomas via the minimally invas... | Endoscopic transorbital; Skull base surgery; Spheno-orbital meningiomas; Systematic review | 0.654 | 123 | Neurology; Surgery | Medicine | 2,023 |
37,024,080 | Microbiologic and Clinical Description of Postoperative Central Nervous System Infection After Endoscopic Endonasal Surgery. | World neurosurgery | World Neurosurg | 175 | null | 10.1016/j.wneu.2023.03.119 | eng | 2,023 | 7 | null | 2,023 | 4 | 5 | [BACKGROUND] Consensus guidelines for antibiotic prophylaxis in endoscopic endonasal surgery (EES) have not been developed. The study objective was to define the microbiologic and clinical characteristics of post-EES central nervous system (CNS) infections. [METHODS] This was a single-center retrospective study of pati... | CNS; Endonasal; Endoscopic; Meningitis | 0.654 | 123 | Neurology; Surgery | Medicine | 2,023 |
37,023,590 | Knee joint underloading does not evolve after a two-week reintroduction to running program after anterior cruciate ligament reconstruction. | Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine | Phys Ther Sport | 61 | null | 10.1016/j.ptsp.2023.03.003 | eng | 2,023 | 5 | null | 2,023 | 3 | 29 | [OBJECTIVES] Knee underloading patterns have been reported mid- and long-term after return to running post-ACLR, but changes in these patterns during the reintroduction to running are unknown. We evaluated knee biomechanics in individuals within 6 months of ACL-R at the start and completion of a reintroduction to runni... | Jogging; Knee loading; Knee sprain; Osteoarthritis | 0.873 | 66 | Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Medicine; Sports Science | Health Professions; Medicine | 2,023 |
37,023,537 | Tranexamic acid as a novel adjunct in the management of vessel perforation complicating Endovascular Clot Retrieval. | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association | J Stroke Cerebrovasc Dis | 32 | 6 | 10.1016/j.jstrokecerebrovasdis.2023.107067 | eng | 2,023 | 6 | null | 2,023 | 4 | 4 | [AIM] To assess the safety and utility of tranexamic acid (TXA) as an adjunct salvage therapy in iatrogenic vessel perforation complicating endovascular clot retrieval. Iatrogenic vessel perforation and extravasation are known and potentially fatal complications of endovascular clot retrieval (ECR). Various methods of ... | null | 0.678 | 85 | Rehabilitation; Cardiology and Cardiovascular Medicine; Neurology; Surgery | Medicine | 2,023 |
37,023,522 | A single case series of imagery rescripting of intrusive autobiographical memories in depression. | Journal of behavior therapy and experimental psychiatry | J Behav Ther Exp Psychiatry | 81 | null | 10.1016/j.jbtep.2023.101854 | eng | 2,023 | 12 | null | 2,023 | 3 | 20 | [BACKGROUND AND OBJECTIVES] Intrusive memories are a common feature of depression, thought to be related to the onset and maintenance of the disorder. Intrusive memories have been successfully targeted in posttraumatic stress disorder through imagery rescripting. Yet there is limited evidence for the effectiveness of t... | Depression; Imagery rescripting; Intrusive memories; Rumination | 0.674 | 94 | Arts and Humanities; Clinical Psychology; Experimental and Cognitive Psychology; Psychiatry and Mental Health | Arts and Humanities; Medicine; Psychology | 2,023 |
37,023,326 | Effectiveness of hospital clowning on pediatric anxiety and pain: Network meta-analysis. | Health psychology : official journal of the Division of Health Psychology, American Psychological Association | Health Psychol | 42 | 4 | 10.1037/hea0001285 | eng | 2,023 | 4 | null | null | null | null | [OBJECTIVE] Anxiety and pain during medical procedures may have adverse short and long-term consequences. We summarize the effectiveness of hospital clown interventions, as compared with medication, the presence of a parent, standard care, and other non-pharmacological distraction interventions on anxiety and pain in m... | null | 1.15 | 194 | Medicine; Psychiatry and Mental Health; Applied Psychology | Medicine; Psychology | 2,023 |
37,023,140 | Knowledge, attitudes, and practices of pediatricians in relation to breastfeeding support: A national survey in Lebanon. | PloS one | PLoS One | 18 | 4 | 10.1371/journal.pone.0281865 | eng | 2,023 | null | null | 2,023 | 4 | 6 | [BACKGROUND] Rates of breastfeeding (BF) remain suboptimal despite overwhelming evidence for its benefits to the mother and child. Pediatricians play an important role in supporting breastfeeding (BF). In Lebanon, the rates of both exclusive and continued BF are critically low. The objective of this study is to examine... | null | 0.839 | 467 | Multidisciplinary | Multidisciplinary | 2,023 |
37,023,021 | COVID-19 and mental health in 8 low- and middle-income countries: A prospective cohort study. | PLoS medicine | PLoS Med | 20 | 4 | 10.1371/journal.pmed.1004081 | eng | 2,023 | 4 | null | 2,023 | 4 | 6 | [BACKGROUND] The Coronavirus Disease 2019 (COVID-19) pandemic and associated mitigation policies created a global economic and health crisis of unprecedented depth and scale, raising the estimated prevalence of depression by more than a quarter in high-income countries. Low- and middle-income countries (LMICs) suffered... | null | 4.198 | 289 | Biochemistry; Biotechnology; Cell Biology; Medicine; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,023 |
37,022,627 | Storytelling, Creativity and Writing as a Tool for Building Sophisticated Social Skills. | Journal of psycholinguistic research | J Psycholinguist Res | 52 | 5 | 10.1007/s10936-023-09949-0 | eng | 2,023 | 10 | null | 2,023 | 4 | 6 | [INTRO] The aim of the work is to prove the effectiveness of the recommendations developed by the authors for introducing the basics of storytelling into the educational process in the context of the development of sophisticated social skills. [METHODS] A survey method was used to determine students' knowledge of story... | Active listening skills; Creative assignment; Journalism; Non-standard approaches; Unique content; communication skills | null | null | null | null | null |
37,021,944 | Preparing Students for Post-COVID Nursing Careers: The Value of International Clinical Placements. | The Journal of nursing education | J Nurs Educ | 62 | 4 | 10.3928/01484834-20230208-03 | eng | 2,023 | 4 | null | 2,023 | 4 | 1 | [BACKGROUND] Prior to the coronavirus disease 2019 (COVID-19) pandemic, international clinical placements (ICPs) for nursing students were used to build cultural humility and global awareness. This study explored the influence of ICPs on nursing students' career planning and views of the nursing role; the findings were... | null | 0.533 | 80 | Education; Nursing | Nursing; Social Sciences | 2,023 |
37,021,929 | Impact of bortezomib-based versus lenalidomide maintenance therapy on outcomes of patients with high-risk multiple myeloma. | Cancer | Cancer | 129 | 14 | 10.1002/cncr.34778 | eng | 2,023 | 7 | 15 | 2,023 | 4 | 6 | [BACKGROUND] Lenalidomide maintenance after autologous stem cell transplant (ASCT) in multiple myeloma (MM) results in superior progression-free survival and overall survival. However, patients with high-risk multiple myeloma (HRMM) do not derive the same survival benefit from lenalidomide maintenance compared with sta... | bortezomib; lenalidomide; maintenance therapy; multiple myeloma; stem cell transplant | 2.887 | 349 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,023 |
37,021,797 | ASO silencing of a glycosyltransferase, Poglut1 , improves the liver phenotypes in mouse models of Alagille syndrome. | Hepatology (Baltimore, Md.) | Hepatology | 78 | 5 | 10.1097/HEP.0000000000000380 | eng | 2,023 | 11 | 1 | 2,023 | 4 | 7 | [BACKGROUND AND AIMS] Paucity of intrahepatic bile ducts (BDs) is caused by various etiologies and often leads to cholestatic liver disease. For example, in patients with Alagille syndrome (ALGS), which is a genetic disease primarily caused by mutations in jagged 1 (JAG1) , BD paucity often results in severe cholestasi... | null | null | null | null | null | null |
37,021,742 | Fetal neurosonography as accurate tool for diagnosis of brain involvement in tuberous sclerosis. | Ultrasound in obstetrics gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology | Ultrasound Obstet Gynecol | 62 | 3 | 10.1002/uog.26213 | eng | 2,023 | 9 | null | null | null | null | [OBJECTIVE] To demonstrate the potential utility of dedicated neurosonography for the diagnosis of fetal brain involvement in tuberous sclerosis complex. [METHODS] This was a multicenter retrospective study of fetuses at high risk for tuberous sclerosis complex. Dedicated neurosonographic, fetal magnetic resonance imag... | fetus; genetics; neurosonography; prenatal diagnosis; rhabdomyoma; tuberous sclerosis complex | null | null | null | null | null |
37,021,475 | Comparison of corticosteroid injection, physiotherapy and combined treatment for patients with chronic subacromial bursitis - A randomised controlled trial. | Clinical rehabilitation | Clin Rehabil | 37 | 9 | 10.1177/02692155231166220 | eng | 2,023 | 9 | null | 2,023 | 4 | 6 | [OBJECTIVE] To investigate whether combination of corticosteroid subdeltoid injections and physiotherapy was more effective than either treatment alone in chronic subacromial bursitis. [DESIGN] Prospective, three-arm randomised controlled trial. [SETTING] Rehabilitation department of an academic hospital. [SUBJECTS] Pa... | Subacromial bursitis; corticosteroid; physical therapy; rehabilitation; subacromial impingement syndrome; therapeutic exercise | 0.949 | 131 | Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation | Health Professions; Medicine | 2,023 |
37,021,234 | The analysis and feedback from the performance of pre-clinical operation skills tests for clerkship in School of Dentistry, National Taiwan University in 2022. | Journal of dental sciences | J Dent Sci | 18 | 2 | 10.1016/j.jds.2023.01.001 | eng | 2,023 | 4 | null | 2,023 | 1 | 18 | [BACKGROUND/PURPOSE] The simulated pre-clinical operation skill test (PCOST) is part of the objective structured clinical examination (OSCE) and designed for clinical practice using manikins, physical typodonts, and instruments in the laboratory. This study tried to evaluate the influencing factors of the PCOST results... | Clerk score; Dental education; Objective structured clinical examination; Pre-clinical operation skills tests; Simulation dental training | 0.758 | 36 | Dentistry | Dentistry | 2,023 |
37,021,033 | Detailed investigation of the lesion formation with a novel contact force sensing catheter with a mesh-shaped irrigation tip. | Journal of arrhythmia | J Arrhythm | 39 | 2 | 10.1002/joa3.12835 | eng | 2,023 | 4 | null | 2,023 | 2 | 27 | [BACKGROUND] Recently, a novel contact force (CF) sensing catheter with mesh-shaped irrigation tip (TactiFlex SE, Abbott) was invented and is expected to be useful for safe and effective radiofrequency ablation. However, this catheter's detailed characteristics of the lesion formation are unknown. [METHODS] With an in ... | TactiFlex catheter; contact force; ex vivo experimental model; lesion size; radiofrequency ablation | 0.545 | 36 | Cardiology and Cardiovascular Medicine | Medicine | 2,023 |
37,021,013 | The efficacy of alpha-lipoic acid in the management of burning mouth syndrome: An updated systematic review of randomized controlled clinical trials. | Health science reports | Health Sci Rep | 6 | 4 | 10.1002/hsr2.1186 | eng | 2,023 | 4 | null | 2,023 | 4 | 3 | [BACKGROUND AND AIMS] Burning mouth syndrome (BMS) causes burning or uncomfortable feelings in the oral cavity without any obvious injuries. This condition's etiopathogenesis is still unknown, consequently, BMS management is very challenging. Alpha-lipoic acid (ALA) is a naturally occurring potent bioactive compound th... | burning mouth syndrome; management; narrative review | 0.578 | 26 | Medicine | Medicine | 2,023 |
37,020,452 | Identifying Conservative Interventions for Individuals with Subacromial Pain Syndrome Prior to Undergoing a Subacromial Decompression: A Scoping Review. | International journal of sports physical therapy | Int J Sports Phys Ther | 18 | 2 | 10.26603/001c.73312 | eng | 2,023 | null | null | 2,023 | 4 | 1 | [BACKGROUND] Subacromial decompression (SAD) surgery remains a common treatment for individuals suffering from subacromial pain syndrome (SAPS), despite numerous studies indicating that SAD provides no benefit over conservative care. Surgical protocols typically recommend surgery only after exhausting conservative meas... | decompression; shoulder impingement syndrome; shoulder pain; surgical | 0.583 | 22 | Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation | Health Professions; Medicine | 2,023 |
37,020,385 | Tuberous sclerosis complex-1 (TSC1) contributes to selective neuronal vulnerability in Alzheimer's disease. | Neuropathology and applied neurobiology | Neuropathol Appl Neurobiol | 49 | 3 | 10.1111/nan.12904 | eng | 2,023 | 6 | null | null | null | null | [AIMS] Selective neuronal vulnerability of hippocampal Cornu Ammonis (CA)-1 neurons is a pathological hallmark of Alzheimer's disease (AD) with an unknown underlying mechanism. We interrogated the expression of tuberous sclerosis complex-1 (TSC1; hamartin) and mTOR-related proteins in hippocampal CA1 and CA3 subfields.... | Alzheimer's disease; molecular biology; neurodegeneration; neuropathology | 1.591 | 111 | Histology; Neurology; Neurology; Pathology and Forensic Medicine; Physiology | Medicine; Neuroscience | 2,023 |
37,020,311 | Strategies to minimise and monitor biases and imbalances by arm in surgical cluster randomised trials: evidence from ChEETAh, a trial in seven low- and middle-income countries. | Trials | Trials | 24 | 1 | 10.1186/s13063-022-06852-2 | eng | 2,023 | 4 | 5 | 2,023 | 4 | 5 | [BACKGROUND] Cluster randomised controlled trials (cRCT) present challenges regarding risks of bias and chance imbalances by arm. This paper reports strategies to minimise and monitor biases and imbalances in the ChEETAh cRCT. [METHODS] ChEETAh was an international cRCT (hospitals as clusters) evaluating whether changi... | Abdominal surgery; Bias; Cluster randomised controlled trial; Global health; Global surgery; Quality assurance; Research methodology; Surgical site infection; Trial management | 0.812 | 103 | Medicine; Pharmacology | Medicine | 2,023 |
37,020,230 | The incomplete circle of Willis is associated with vulnerable intracranial plaque features and acute ischemic stroke. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance | J Cardiovasc Magn Reson | 25 | 1 | 10.1186/s12968-023-00931-2 | eng | 2,023 | 4 | 6 | 2,023 | 4 | 6 | [BACKGROUND] The circle of Willis (CoW) plays a significant role in intracranial atherosclerosis (ICAS). This study investigated the relationship between different types of CoW, atherosclerosis plaque features, and acute ischemic stroke (AIS). [METHODS] We investigated 97 participants with AIS or transient ischemic att... | Circle of Willis; Intracranial atherosclerosis; Ischemic stroke; Magnetic resonance imaging; Transient ischemic attack | 2.242 | 119 | Cardiology and Cardiovascular Medicine; Family Practice; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging | Health Professions; Medicine | 2,023 |
37,020,032 | Does intraoperative patellar eversion affect clinical and functional outcomes in patients undergoing primary total knee arthroplasty? An evidence-based meta-analysis. | International orthopaedics | Int Orthop | 47 | 8 | 10.1007/s00264-023-05797-8 | eng | 2,023 | 8 | null | 2,023 | 4 | 6 | [PURPOSE] This meta-analysis aims to compare the early postoperative recovery, complications encountered, length of hospital stay, and initial functional scores between patellar eversion and non-eversion manoeuvres in patients undergoing during primary total knee arthroplasty (TKA) based on clinical studies available i... | Knee exposure; Outcome analysis; Patellar eversion; Patellar retraction; Total knee arthroplasty | 0.877 | 116 | Orthopedics and Sports Medicine; Surgery | Medicine | 2,023 |
37,019,804 | Smartphone Recordings are Comparable to "Gold Standard" Recordings for Acoustic Measurements of Voice. | Journal of voice : official journal of the Voice Foundation | J Voice | 39 | 4 | 10.1016/j.jvoice.2023.01.031 | eng | 2,025 | 7 | null | 2,023 | 4 | 4 | [PURPOSE] The purpose of this study was to assess the relationship and comparability of cepstral and spectral measures of voice obtained from a high-cost "flat" microphone and precision sound level meter (SLM) vs. high-end and entry level models of commonly and currently used smartphones (iPhone i12 and iSE; Samsung s2... | cepstral analysis; frequency response; smartphones; spectral analysis; voice evaluation | 0.573 | 114 | LPN and LVN; Otorhinolaryngology; Speech and Hearing | Health Professions; Medicine; Nursing | 2,024 |
37,019,724 | Electrotaxis of alveolar epithelial cells in direct-current electric fields. | Chinese journal of traumatology = Zhonghua chuang shang za zhi | Chin J Traumatol | 26 | 3 | 10.1016/j.cjtee.2023.03.003 | eng | 2,023 | 5 | null | 2,023 | 3 | 28 | [PURPOSE] This study aims to elucidate the electrotaxis response of alveolar epithelial cells (AECs) in direct-current electric fields (EFs), explore the impact of EFs on the cell fate of AECs, and lay the foundation for future exploitation of EFs for the treatment of acute lung injury. [METHODS] AECs were extracted fr... | Acute lung injury; Alveolar epithelial cells; Electric fields; Electrotaxis; Migration | null | null | null | null | null |
37,019,327 | Predicting thalassemia using deep neural network based on red blood cell indices. | Clinica chimica acta; international journal of clinical chemistry | Clin Chim Acta | 543 | null | 10.1016/j.cca.2023.117329 | eng | 2,023 | 3 | 15 | 2,023 | 4 | 3 | [BACKGROUND AND OBJECTIVE] The traditional statistical screening method for thalassemia based on red blood cell (RBC) indices is being replaced by machine learning. Here, we developed deep neural networks (DNNs) that outperformed the traditional method for predicting thalassemia. [METHOD] Using a dataset of 8693 record... | ANN; DNN; MCH; MCV; red blood cell indices; thalassemia screening | null | null | null | null | null |
37,019,195 | Evaluation of obstructive sleep apnea among consecutive patients with all patterns of atrial fibrillation using WatchPAT home sleep testing. | American heart journal | Am Heart J | 261 | null | 10.1016/j.ahj.2023.03.014 | eng | 2,023 | 7 | null | 2,023 | 4 | 3 | [BACKGROUND] Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice and is associated with significant morbidity, mortality, and financial burden. Obstructive sleep apnea (OSA) is more common in individuals with AF and may impair the efficacy of rhythm control strategies including cathe... | null | 2.109 | 211 | Cardiology and Cardiovascular Medicine | Medicine | 2,023 |
37,019,089 | Anemia Is Associated with Disease Severity, Hepatic Complications, and Progression of Wilson Disease: A Retrospective Cohort Study. | Digestive diseases (Basel, Switzerland) | Dig Dis | 41 | 4 | 10.1159/000530473 | eng | 2,023 | null | null | 2,023 | 4 | 5 | [INTRODUCTION] Anemia is a common manifestation of chronic liver diseases. It is a predictor of severe disease, a high risk of complications, and poor outcomes in various liver diseases. However, it remains unclear whether anemia serves as a similar indicator in patients with Wilson disease (WD). Therefore, this study ... | Anemia; Disease progression; Hepatic encephalopathy; Liver cirrhosis | 0.744 | 83 | Gastroenterology; Medicine | Medicine | 2,023 |
37,018,860 | Evaluating the effectiveness of interventions: A comprehensive scoring system versus testing for statistical significance. | European journal of obstetrics, gynecology, and reproductive biology | Eur J Obstet Gynecol Reprod Biol | 285 | null | 10.1016/j.ejogrb.2023.03.044 | eng | 2,023 | 6 | null | 2,023 | 4 | 1 | [BACKGROUND] Medical practice relies on reliable research observations. Whether such observations are true is traditionally tested by hypotheses and expressed with P-values. A strict P-value driven interpretation could potentially deny benefits of treatment. [OBJECTIVE] A strict P-value driven interpretation was compar... | Data interpretation; Gynaecology; Obstetrics; P-value; Research data; Statistical significance | null | null | null | null | null |
37,018,593 | Evaluation of Brain Source Localization Methods Based on Test-Retest Reliability With Multiple Session EEG Data. | IEEE transactions on bio-medical engineering | IEEE Trans Biomed Eng | 70 | 7 | 10.1109/TBME.2023.3235377 | eng | 2,023 | 7 | null | 2,023 | 6 | 19 | [OBJECTIVE] Various EEG source localization methods have been proposed for functional brain research. The evaluation and comparison of these methods are usually based on simulated data but not real EEG data, as the ground truth of source localization is unknown. In this study, we aim to evaluate source localization met... | null | null | null | null | null | null |
37,018,518 | Combinations of Digital Breast Tomosynthesis and Full-field Digital Mammography for Different Density Types of Breasts. | Current medical imaging | Curr Med Imaging | null | null | 10.2174/1573405620666230328085655 | eng | 2,023 | 3 | 28 | 2,023 | 3 | 28 | [BACKGROUND] The combination of FFDM and DBT can significantly improve the diagnostic efficiency of breast cancer, but with the increase of breast radiation absorbed dose. [OBJECTIVES] To compare and analyze the radiation dose and diagnostic performance of different mammography positions combinations of digital breast ... | absorbed radiation dose; cross-sectional synthesis technique; diagnosis; digital breast tomosynthesis; digital mammography; two-view combination | 0.288 | 27 | Internal Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,023 |
37,018,346 | The moderating role of neighborhood disadvantage on the link between functional limitations and self-rated health. | PloS one | PLoS One | 18 | 4 | 10.1371/journal.pone.0283796 | eng | 2,023 | null | null | 2,023 | 4 | 5 | [BACKGROUND] Self-rated health is an important health outcome and determinant of health. Improvements to our understanding on self-rated health could help design plans and strategies to improve self-rated health and achieve other preferred health outcomes. This study examined whether the link between functional limitat... | null | 0.839 | 467 | Multidisciplinary | Multidisciplinary | 2,023 |
37,018,218 | Healthcare resource utilisation and cost of pneumococcal disease from 2003 to 2019 in children ≤17 years in England. | PloS one | PLoS One | 18 | 4 | 10.1371/journal.pone.0283084 | eng | 2,023 | null | null | 2,023 | 4 | 5 | [OBJECTIVE] To estimate healthcare resource utilisation (HCRU) and costs associated with pneumococcal disease (PD) in children aged ≤17 years in England from 2003-2019. [METHODS] A retrospective study in children aged ≤17 years was conducted using the Clinical Practice Research Datalink Gold primary care database and H... | null | 0.839 | 467 | Multidisciplinary | Multidisciplinary | 2,023 |
37,018,013 | Lessons for Vietnam on the Use of Digital Technologies to Support Patient-Centered Care in Low- and Middle-Income Countries in the Asia-Pacific Region: Scoping Review. | Journal of medical Internet research | J Med Internet Res | 25 | null | 10.2196/43224 | eng | 2,023 | 4 | 5 | 2,023 | 4 | 5 | [BACKGROUND] A rapidly aging population, a shifting disease burden and the ongoing threat of infectious disease outbreaks pose major concerns for Vietnam's health care system. Health disparities are evident in many parts of the country, especially in rural areas, and the population faces inequitable access to patient-c... | Asia-Pacific region; Vietnam; clinical; database; digital; digital health; digital health technologies; disease; eHealth; mHealth; mobile health; patient-centered care; self-management; technology; users | 2.02 | 214 | Health Informatics | Medicine | 2,023 |
37,017,876 | Sputum culture and antibiotic resistance in elderly inpatients with exacerbation of chronic obstructive pulmonary disease at a tertiary geriatric hospital in southern Vietnam. | Aging clinical and experimental research | Aging Clin Exp Res | 35 | 6 | 10.1007/s40520-023-02401-2 | eng | 2,023 | 6 | null | 2,023 | 4 | 5 | [OBJECTIVE] To determine the rate of positive culture sputum and related factors as well as the microorganism features and antibiotic susceptibility of pathogens in elderly inpatients with exacerbation of chronic obstructive pulmonary disease (COPD) in Thong Nhat Hospital, Vietnam. [METHODS] This cross-sectional study ... | Antibiogram; Chronic obstructive pulmonary disease (COPD); Exacerbation of COPD; Vietnam | 1.005 | 95 | Aging; Geriatrics and Gerontology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,023 |
37,017,465 | Effect of an N95 respirator and a surgical mask-covered N95 on the cardiovascular responses of dentists treating paediatric patients: A crossover clinical trial. | International journal of paediatric dentistry | Int J Paediatr Dent | 33 | 4 | 10.1111/ipd.13068 | eng | 2,023 | 7 | null | 2,023 | 4 | 12 | [BACKGROUND] The studies on cardiovascular alterations when using an N95 respirator or surgical mask-covered N95 during dental treatments are limited. [AIM] To investigate and compare the cardiovascular responses of dentists treating paediatric patients while wearing an N95 respirator or a surgical mask-covered N95. [D... | N95 respirator; blood pressure; heart rate; oxygen saturation; paediatric dentist; surgical mask | 0.885 | 81 | Dentistry | Dentistry | 2,023 |
37,017,281 | Association Between Vitamin D Levels and COVID-19 Infection in Children: A Case-Control Study. | Turkish archives of pediatrics | Turk Arch Pediatr | 58 | 3 | 10.5152/TurkArchPediatr.2023.22217 | eng | 2,023 | 5 | null | null | null | null | [OBJECTIVE] Coronavirus disease 2019 (COVID-19) infection is seen in all age groups, and its symptoms are very variable. The course of the disease can be asymptomatic or mortal. In pediatric patients, vitamin D is thought to be protective against (COVID-19) with its immunomodulator, antiviral, anti-inflammatory, and ep... | null | 0.321 | 24 | Pediatrics, Perinatology and Child Health | Medicine | 2,023 |
37,017,118 | Economic burden of skin and skin structure infections due to Gram-positive bacteria in patients on hospital at home-based outpatient parenteral antibiotic therapy (OPAT). | Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia | Rev Esp Quimioter | 36 | 3 | 10.37201/req/134.2022 | eng | 2,023 | 6 | null | 2,023 | 4 | 5 | [OBJECTIVE] To describe and quantify resource use and direct health costs associated with skin and skin structure infections (SSSIs) caused by Gram-positive bacteria in adults receiving outpatient parenteral antimicrobial therapy (OPAT), administered by Hospital at Home units (HaH) in Spain. [METHODS] Observational, mu... | Hospital at home; cost analysis; outpatient parenteral antimicrobial therapy; skin and skin structure infections | 0.399 | 35 | Medicine; Microbiology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,023 |
37,016,866 | Reduction of Lower Cervical Facet Dislocation: A Review of All Techniques. | Neurospine | Neurospine | 20 | 1 | 10.14245/ns.2244852.426 | eng | 2,023 | 3 | null | 2,023 | 3 | 31 | [OBJECTIVE] The surgical treatment of lower cervical facet dislocation is controversial. Great advancements on reduction techniques for lower cervical facet dislocation have been made in the past decades. However, there is no article reviewing all the reduction techniques yet. The aim is to review the evolution and adv... | Facet dislocation; Lower cervical spine; Review; Techniques | 1.331 | 37 | Neurology; Surgery | Medicine | 2,023 |
37,016,749 | Online and onsite supervised exercise therapy and education for individuals with knee osteoarthritis - A before and after comparison of two different care delivery models. | Musculoskeletal care | Musculoskeletal Care | 21 | 3 | 10.1002/msc.1765 | eng | 2,023 | 9 | null | 2,023 | 4 | 4 | [OBJECTIVE] To compare the 3 and 12-month changes on pain, function and quality of life between online and onsite delivery of Good Life with Osteoarthritis in Denmark (GLA:D[®]) in individuals with knee osteoarthritis (OA). [DESIGN] Non-inferior comparison of individuals with knee OA receiving physiotherapist-supervise... | exercise; knee; online; osteoarthritis; rehabilitation | 0.56 | 38 | Chiropractics; Nursing; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Rheumatology | Health Professions; Medicine; Nursing | 2,023 |
37,016,604 | A Randomized Double-Blind, Placebo-Controlled Study to Evaluate the Anti-Skin-Aging Effect of LactoSporin - The Extracellular Metabolite from Bacillus coagulans (Weizmannia coagulans) MTCC 5856 in Healthy Female Volunteers. | Clinical, cosmetic and investigational dermatology | Clin Cosmet Investig Dermatol | 16 | null | 10.2147/CCID.S403418 | eng | 2,023 | null | null | 2,023 | 3 | 29 | [PURPOSE] There has been a growing interest in the use of probiotics and their products for skin care, over the last decade. LactoSporin is the extracellular metabolite of a spore-forming probiotic Bacillus coagulans (Weizmannia coagulans) MTCC 5856, with antimicrobial and skin protecting activity. [PATIENTS AND METHOD... | LactoSporin; corneometer; cutometer; dermatological assessments; safety; tewameter | 0.584 | 59 | Dermatology | Medicine | 2,023 |
37,016,481 | Does a Modified Frailty Index Predict 30-day Complications After Long-Bone Nonunion or Malunion Surgery? | Journal of orthopaedic trauma | J Orthop Trauma | 37 | 8 | 10.1097/BOT.0000000000002609 | eng | 2,023 | 8 | 1 | null | null | null | [OBJECTIVE] To assess the ability of a modified frailty index (mFI-5) score, which includes the presence of congestive heart failure, hypertension, chronic obstructive pulmonary disease, diabetes, and nonindependent functional status, and to identify patients at increased risk of complications after surgical treatment ... | null | 0.965 | 150 | Medicine; Orthopedics and Sports Medicine; Surgery; Sports Science | Health Professions; Medicine | 2,023 |
37,016,381 | Post-traumatic stress disorders, anxiety, and depression in college students during the COVID-19 pandemic: a cross-sectional study. | BMC psychiatry | BMC Psychiatry | 23 | 1 | 10.1186/s12888-023-04660-9 | eng | 2,023 | 4 | 4 | 2,023 | 4 | 4 | [OBJECTIVES] The COVID-19 pandemic has caused an increase in psychiatric disorders in college students, particularly posttraumatic stress disorders (PTSD), depression, and anxiety. While existing studies assess the prevalence of these disorders and their predictors, they overlook potential complications caused by comor... | Anxiety; COVID-19; College students; Depression; PTSD | 1.301 | 151 | Psychiatry and Mental Health | Medicine | 2,023 |
37,016,340 | Design and analysis of outcomes following SARS-CoV-2 infection in veterans. | BMC medical research methodology | BMC Med Res Methodol | 23 | 1 | 10.1186/s12874-023-01882-z | eng | 2,023 | 4 | 4 | 2,023 | 4 | 4 | [BACKGROUND] Understanding how SARS-CoV-2 infection impacts long-term patient outcomes requires identification of comparable persons with and without infection. We report the design and implementation of a matching strategy employed by the Department of Veterans Affairs' (VA) COVID-19 Observational Research Collaborato... | COVID-19; Causal inference; Longitudinal; Matching; Retrospective; Study design; Veterans | 1.632 | 176 | Epidemiology; Health Informatics | Medicine | 2,023 |
37,016,313 | Quality of systematic reviews on timing of complementary feeding for early childhood allergy prevention. | BMC medical research methodology | BMC Med Res Methodol | 23 | 1 | 10.1186/s12874-023-01899-4 | eng | 2,023 | 4 | 4 | 2,023 | 4 | 4 | [BACKGROUND] Only rigorously prepared analyses can provide the highest level of evidence to inform decision-making. Several recent systematic reviews (SRs) examined the hypothesis that the early introduction of specific allergenic complementary foods (CFs) to infants may lead to a lower incidence of one or more allergi... | Allergy prevention; Complementary feeding; Methodological quality; Risk of bias; Systematic review | 1.632 | 176 | Epidemiology; Health Informatics | Medicine | 2,023 |
37,016,284 | Cytokines in primary headache disorders: a systematic review and meta-analysis. | The journal of headache and pain | J Headache Pain | 24 | 1 | 10.1186/s10194-023-01572-7 | eng | 2,023 | 4 | 4 | 2,023 | 4 | 4 | [BACKGROUND] The role of inflammation and cytokines in the pathophysiology of primary headache disorders is uncertain. We performed a systematic review and meta-analysis to synthesise the results of studies comparing peripheral blood cytokine levels between patients with migraine, tension-type headache, cluster headach... | Cytokine; Immunology; Migraine disorders; Neurogenic inflammation; Tension-type headache | 1.791 | 97 | Anesthesiology and Pain Medicine; Medicine; Neurology | Medicine | 2,023 |
37,015,843 | Assessing the Prevalence and Associated Risk Factors for Presbylarynx in the Elderly Laryngology Population. | Journal of voice : official journal of the Voice Foundation | J Voice | null | null | 10.1016/j.jvoice.2023.03.006 | eng | 2,023 | 4 | 2 | 2,023 | 4 | 2 | [OBJECTIVE] The primary objective of this study was to assess the prevalence of presbylarynx and its associated features in an elderly population representative of patients seen in a tertiary care laryngology practice. The secondary objective of this study was to compare laryngeal electromyography (LEMG) findings, coex... | null | 0.578 | 114 | LPN and LVN; Otorhinolaryngology; Speech and Hearing | Health Professions; Medicine; Nursing | 2,023 |
37,015,786 | Stress load and volunteer motivation of patient volunteers in Fangcang shelter hospitals in Shanghai, China during the COVID-19 pandemic: a cross-sectional survey. | BMJ open | BMJ Open | 13 | 4 | 10.1136/bmjopen-2022-066930 | eng | 2,023 | 4 | 4 | 2,023 | 4 | 4 | [OBJECTIVES] This study aims to assess the volunteer motivation and stress load of patient volunteers in the Fangcang shelter hospitals (FSHs), examine their associations, and explore the potential influence factors of volunteer motivation. [DESIGN] Cross-sectional online survey conducted from 21 April to 20 May 2022. ... | COVID-19; adult psychiatry; health services administration management; mental health; public health | 0.971 | 176 | Medicine | Medicine | 2,023 |
37,015,760 | Cancer cell genotype associated tumor immune microenvironment exhibits differential response to therapeutic STING pathway activation in high-grade serous ovarian cancer. | Journal for immunotherapy of cancer | J Immunother Cancer | 11 | 4 | 10.1136/jitc-2022-006170 | eng | 2,023 | 4 | null | null | null | null | [BACKGROUND] High-grade serous ovarian carcinoma (HGSC) is the most lethal gynecologic malignancy characterized by resistance to chemotherapy and high rates of recurrence. HGSC tumors display a high prevalence of tumor suppressor gene loss. Given the type 1 interferon regulatory function of BRCA1 and PTENgenes and thei... | Genital Neoplasms, Female; Immunomodulation; Immunotherapy; Interferon Inducers; Tumor Microenvironment | 3.728 | 136 | Cancer Research; Immunology; Immunology and Allergy; Molecular Medicine; Oncology; Pharmacology | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,023 |
37,015,754 | Helicobacter pylori promotes colorectal carcinogenesis by deregulating intestinal immunity and inducing a mucus-degrading microbiota signature. | Gut | Gut | 72 | 7 | 10.1136/gutjnl-2022-328075 | eng | 2,023 | 7 | null | 2,023 | 4 | 4 | [OBJECTIVE] Helicobacter pylori infection is the most prevalent bacterial infection worldwide. Besides being the most important risk factor for gastric cancer development, epidemiological data show that infected individuals harbour a nearly twofold increased risk to develop colorectal cancer (CRC). However, a direct ca... | Helicobacter pylori; colonic microflora; colorectal cancer; immune response; signaling | 8.052 | 364 | Gastroenterology | Medicine | 2,023 |
37,015,675 | OCTAve: 2D En Face Optical Coherence Tomography Angiography Vessel Segmentation in Weakly-Supervised Learning With Locality Augmentation. | IEEE transactions on bio-medical engineering | IEEE Trans Biomed Eng | 70 | 6 | 10.1109/TBME.2022.3232102 | eng | 2,023 | 6 | null | 2,023 | 5 | 19 | [OBJECTIVE] While the microvasculature annotation within Optical Coherence Tomography Angiography (OCTA) can be leveraged using deep-learning techniques, expensive annotation processes are required to create sufficient training data. One way to avoid the expensive annotation is to use a type of weak annotation in which... | null | null | null | null | null | null |
37,015,340 | Nationwide Trends and Determinants of Germline BRCA1/2 Testing in Patients With Breast and Ovarian Cancer. | Journal of the National Comprehensive Cancer Network : JNCCN | J Natl Compr Canc Netw | 21 | 4 | 10.6004/jnccn.2022.7257 | eng | 2,023 | 4 | null | null | null | null | [BACKGROUND] Germline genetic testing (GT) for BRCA1/2 is instrumental in identifying patients with breast and ovarian cancers who are eligible for PARP inhibitors (PARPi). Little is known about recent trends and determinants of GT since PARPi were approved for these patients. [PATIENTS AND METHODS] We performed a retr... | Ovarian cancer; breast cancer; germline genetic testing; guideline adherence | null | null | null | null | null |
37,015,322 | Racial/Ethnic Differences in Risk Factors Associated With Severe COVID-19 Among Older Adults With ADRD. | Journal of the American Medical Directors Association | J Am Med Dir Assoc | 24 | 6 | 10.1016/j.jamda.2023.02.111 | eng | 2,023 | 6 | null | 2,023 | 3 | 9 | [OBJECTIVE] To examine racial/ethnic differences in risk factors, and their associations with COVID-19-related outcomes among older adults with Alzheimer's disease and related dementias (ADRD). [DESIGN] Observational study. [SETTING AND PARTICIPANTS] National Medicare claims data and the Minimum Data Set 3.0 from April... | COVID-19; Older adults with ADRD; machine learning; racial/ethnic differences | 1.592 | 136 | Geriatrics and Gerontology; Health Policy; Medicine; Nursing | Medicine; Nursing | 2,023 |
37,015,310 | The Relation Between Obesity and Mortality in Postcardiotomy Venoarterial Membrane Oxygenation. | The Annals of thoracic surgery | Ann Thorac Surg | 116 | 1 | 10.1016/j.athoracsur.2023.03.025 | eng | 2,023 | 7 | null | 2,023 | 4 | 2 | [BACKGROUND] Obesity is an important health problem in cardiac surgery and among patients requiring postcardiotomy venoarterial extracorporeal membrane oxygenation (V-A ECMO). Still, whether these patients are at risk for unfavorable outcomes after postcardiotomy V-A ECMO remains unclear. The current study evaluated th... | null | 1.203 | 230 | Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery | Medicine | 2,023 |
37,015,210 | International Variability of Renal and Cardiovascular Outcomes and Mortality in Patients with Type 2 Diabetes Mellitus in Europe. | Kidney blood pressure research | Kidney Blood Press Res | 48 | 1 | 10.1159/000528438 | eng | 2,023 | null | null | 2,023 | 4 | 4 | [INTRODUCTION] Type 2 diabetes and its complications represent a huge burden to public health. With this prospective, observational cohort study, we aimed to estimate and to compare the incidence rate (IR) of renal and cardiovascular outcomes and all-cause mortality in patients with type 2 diabetes in different Europea... | Cardiovascular disease; Diabetes mellitus; Diabetic nephropathy; Epidemiology; Outcome | null | null | null | null | null |
37,014,967 | Polyphonic perspectives: a focus group study of interprofessional staff's perceptions of music therapy at an inpatient unit for children in mental health care. | International journal of qualitative studies on health and well-being | Int J Qual Stud Health Well-being | 18 | 1 | 10.1080/17482631.2023.2197750 | eng | 2,023 | 12 | null | null | null | null | [PURPOSE] In an inpatient unit for children in mental health care, a variety of services are provided through interprofessional collaborations. Music therapy is a relatively recent proposition in this context, but there is increasing acceptance for music therapy as a therapeutic method. However, there is limited knowle... | Children; Focus group interviews; Interprofessional perspectives; Mental health care; Music Therapy | 0.768 | 51 | Fundamentals and Skills; Issues, Ethics and Legal Aspects; Gerontology; Health Policy | Medicine; Nursing | 2,023 |
37,014,516 | Leukoaraiosis severity is related to increased risk of early neurological deterioration in acute ischemic stroke: a retrospective observational study. | Acta neurologica Belgica | Acta Neurol Belg | 123 | 4 | 10.1007/s13760-023-02249-3 | eng | 2,023 | 8 | null | 2,023 | 4 | 4 | [OBJECTIVES] The relationship between leukoaraiosis and early neurological deterioration in acute cerebral infarction patients remains controversial. We tried to determine whether an association existed between leukoaraiosis and early neurological deterioration in patients with acute ischemic stroke. [MATERIALS AND MET... | Cerebral infarction; Early neurological deterioration; Leukoaraiosis; Stroke | 0.58 | 44 | Medicine; Neurology | Medicine | 2,023 |
37,014,390 | Post hip fracture orthogeriatric care-a Canadian position paper addressing challenges in care and strategies to meet quality indicators. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA | Osteoporos Int | 34 | 6 | 10.1007/s00198-022-06640-3 | eng | 2,023 | 6 | null | 2,023 | 4 | 4 | [INTRODUCTION] Osteoporosis is a major disease state associated with significant morbidity, mortality, and health care costs. Less than half of the individuals sustaining a low energy hip fracture are diagnosed and treated for the underlying osteoporosis. [OBJECTIVE] A multidisciplinary Canadian hip fracture working gr... | Clinical guidelines; Hip fracture; Orthogeriatric care; Quality indicators | 1.111 | 201 | Endocrinology, Diabetes and Metabolism; Medicine | Medicine | 2,023 |
37,014,367 | Reconsidering the effectiveness of low-dose aspirin in prevention of pre-eclampsia among otherwise low risk twin gestations: A historical cohort study. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics | Int J Gynaecol Obstet | 162 | 3 | 10.1002/ijgo.14754 | eng | 2,023 | 9 | null | 2,023 | 4 | 4 | [OBJECTIVE] To investigate the effectiveness of low-dose aspirin (LDA) in the prevention of pre-eclampsia (PE) among otherwise low-risk twin gestations. [METHODS] A historical cohort study consisting of all pregnant individuals with dichorionic diamniotic (DCDA) twin pregnancy who delivered between 2014 and 2020. Patie... | low-dose aspirin; placenta pre-eclampsia; preterm pre-eclampsia; twin gestation | null | null | null | null | null |
37,014,141 | Investigating the effect of the pH of foot care product formulations on pedal skin in diabetic and non-diabetic subjects. | International journal of cosmetic science | Int J Cosmet Sci | 45 | 4 | 10.1111/ics.12861 | eng | 2,023 | 8 | null | 2,023 | 4 | 27 | [OBJECTIVE] The use of skin care formulations with acidic pHs is seen as an effective method to maintain the acidic mantel of the skin; however, because the skin pH varies depending on the area of the body and as data are lacking for the skin pH of the feet, there was a need to examine whether this assumption holds tru... | claim substantiation; foot creams; safety testing; skin moisture; skin pH | 0.552 | 83 | Chemistry; Colloid and Surface Chemistry; Dermatology; Drug Discovery; Pharmaceutical Science; Aging | Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,023 |
37,013,871 | Impact of leadership on the nursing workforce during the COVID-19 pandemic. | BMJ leader | BMJ Lead | 7 | 1 | 10.1136/leader-2021-000588 | eng | 2,023 | 3 | null | 2,022 | 5 | 13 | [BACKGROUND] The aim was to determine how the learning about protective factors from previous pandemics was implemented and the impact of this on nurses' experience. [METHODS] Secondary data analysis of semistructured interview transcripts exploring the barriers and facilitators to changes implemented to support the su... | COVID-19; analysis; communication; healthcare planning; nurse | 0.483 | 19 | Leadership and Management; Strategy and Management; Health Policy | Business, Management and Accounting; Medicine; Nursing | 2,023 |
37,013,870 | Reflection of leadership skills by a clinical educator. | BMJ leader | BMJ Lead | 7 | 1 | 10.1136/leader-2021-000477 | eng | 2,023 | 3 | null | 2,022 | 3 | 30 | [BACKGROUND] A leader can only motivate people to do what they want them to do to convince them that it is advantageous. No one can be forced into leadership. Through my experience, I learnt that excellent leadership realises the desired results by getting people to do their best. [METHOD] Therefore, I would like to re... | COVID-19; clinical leadership; continuous improvement; leadership assessment; medical leadership | 0.483 | 19 | Leadership and Management; Strategy and Management; Health Policy | Business, Management and Accounting; Medicine; Nursing | 2,023 |
37,013,632 | Hyperlipasemia in dogs with acute kidney injury treated with and without hemodialysis. | Journal of veterinary internal medicine | J Vet Intern Med | 37 | 3 | 10.1111/jvim.16693 | eng | 2,023 | null | null | 2,023 | 4 | 4 | [BACKGROUND] Hyperlipasemia has been reported in dogs with acute kidney injury (AKI) but associations with AKI severity, hemodialysis (HD) treatment, and outcome have not been extensively evaluated. [OBJECTIVES] Investigate the prevalence and clinical relevance of hyperlipasemia in dogs with AKI, treated with and witho... | acute pancreatitis; canine; lipase; pancreatic enzymes; renal replacement therapy | 0.988 | 130 | Medicine; Veterinary | Medicine; Veterinary | 2,023 |
37,013,580 | A novel small molecule, AS1, reverses the negative hedonic valence of noxious stimuli. | BMC biology | BMC Biol | 21 | 1 | 10.1186/s12915-023-01573-7 | eng | 2,023 | 4 | 3 | 2,023 | 4 | 3 | [BACKGROUND] Pain is the primary reason people seek medical care, with chronic pain affecting ~ 20% of people in the USA. However, many existing analgesics are ineffective in treating chronic pain, while others (e.g., opioids) have undesirable side effects. Here, we describe the screening of a small molecule library us... | Analgesic; Aversion; Dopamine; Drug discovery; Pain; Reward circuitry; Valence; Zebrafish | null | null | null | null | null |
37,013,566 | Use of LARS for soft tissue function reconstruction during tumor-type hemi-shoulder replacement achieves a good prognosis: a retrospective cohort study. | World journal of surgical oncology | World J Surg Oncol | 21 | 1 | 10.1186/s12957-023-03008-7 | eng | 2,023 | 4 | 4 | 2,023 | 4 | 4 | [BACKGROUND] Shoulder soft tissue function reconstruction during tumor-type hemishoulder replacement is an important step to restore shoulder function. This study evaluates the functional prognosis and postoperative complications of ligament advanced reinforcement system (LARS)-assisted soft tissue functional reconstru... | Function reconstruction; LARS; Limb salvage; Muscle dynamic system; Tumor-type hemi-shoulder replacement | 0.733 | 82 | Surgery; Oncology | Medicine | 2,023 |
37,013,526 | Assessing bystander first aid: development and validation of a First Aid Quality Assessment (FAQA) tool. | BMC emergency medicine | BMC Emerg Med | 23 | 1 | 10.1186/s12873-023-00811-z | eng | 2,023 | 4 | 4 | 2,023 | 4 | 4 | [BACKGROUND] Injuries are one of the leading causes of death worldwide. Bystanders at the scene can perform first aid measures before the arrival of health services. The quality of first aid measures likely affects patient outcome. However, scientific evidence on its effect on patient outcome is limited. To properly as... | Bystander; First aid; Injury; Trauma; Validate | 0.745 | 51 | Emergency Medicine | Medicine | 2,023 |
37,013,515 | Psychosocial and behavioral outcomes in the adult workforce during the COVID-19 pandemic: a 1-Year longitudinal survey. | BMC public health | BMC Public Health | 23 | 1 | 10.1186/s12889-023-15536-8 | eng | 2,023 | 4 | 3 | 2,023 | 4 | 3 | [BACKGROUND] Efforts to limit the spread of COVID-19 have included public space closures, mask usage, and quarantining. Studies regarding the impact of these measures on the psychosocial and behavioral health outcomes of the workforce have focused frequently on healthcare employees. To expand the literature base, we de... | Behavioral health; COVID-19; Longitudinal study; Psychosocial health | 1.253 | 211 | Public Health, Environmental and Occupational Health | Medicine | 2,023 |
37,013,438 | Vaccine-Induced or Hybrid Immunity and COVID-19-Associated Mortality During the Omicron Wave. | Deutsches Arzteblatt international | Dtsch Arztebl Int | 120 | 13 | 10.3238/arztebl.m2023.0051 | eng | 2,023 | 3 | 31 | null | null | null | [BACKGROUND] It is not yet entirely clear to what extent vaccine-induced or hybrid immunity offers protection from death during the omicron wave of the COVID-19 pandemic in Germany. [METHODS] In this retrospective study, we evaluated 470 159 cases aged ≥ 60 years in the German federal state of Bavaria who tested positi... | null | 0.468 | 97 | Medicine | Medicine | 2,023 |
37,013,292 | A gender-based study of symptoms and risk factors associated with mortality in COVID-19 patients in a tertiary care hospital, Lahore. | JPMA. The Journal of the Pakistan Medical Association | J Pak Med Assoc | 72 | 11 | 10.47391/JPMA.4867 | eng | 2,022 | 11 | null | null | null | null | [OBJECTIVE] To determine the symptoms and risk factors associated with gender-specific mortality among coronavirus disease-2019 patients. [METHODS] The retrospective, descriptive, cross-sectional study was conducted at the coronavirus disease-2019 ward of the Jinnah Hospital, Lahore, Pakistan, and comprised record of c... | Mortality, Gender, Risk factors. | null | null | null | null | null |
37,013,282 | Assessment of quality of life of stroke survivors and their caregivers presenting to a tertiary care hospital in Pakistan. | JPMA. The Journal of the Pakistan Medical Association | J Pak Med Assoc | 72 | 11 | 10.47391/JPMA.3911 | eng | 2,022 | 11 | null | null | null | null | [OBJECTIVE] To determine the quality of life of stroke survivors and their caregivers presenting to a tertiary care setup. [METHODS] The descriptive study was conducted from July to December 2019 at the Neurology Department, Pakistan Institute of Medical Sciences, Islamabad, Pakistan, and comprised patients of either g... | null | null | null | null | null | null |
37,013,243 | Outcome Analysis of En bloc Resection and Reconstruction by Non-vascularized Proximal Fibular Autograft in Giant Cell Tumor of Distal Radius supplemented with Brachytherapy. | Journal of orthopaedic case reports | J Orthop Case Rep | 12 | 11 | 10.13107/jocr.2022.v12.i11.3418 | eng | 2,022 | 11 | null | null | null | null | [INTRODUCTION] Giant cell tumors of the bone are aggressive and potentially malignant lesions. Juxtaarticular giant cell tumors of the lower end radius are common and is a challenge for reconstruction after tumor excision. Several reconstructive procedures like vascularized and non-vascularized fibular graft, osteoarti... | GCT; brachytherapy; en bloc resection; recurrence | null | null | null | null | null |
37,013,225 | Closed Reduction of Chronically Subluxated knee with Deftix (Made in India Hexapod). | Journal of orthopaedic case reports | J Orthop Case Rep | 12 | 11 | 10.13107/jocr.2022.v12.i11.3410 | eng | 2,022 | 11 | null | null | null | null | [INTRODUCTION] The aim of the study was to study results of (made in India) hexapod external fixator (HEF) (deft fix)-assisted correction in a case of knee subluxation with malunited medial tibial condyle fracture. [METHODOLOGY] A subject with knee subluxation was selected for application of hexapod and Ilizarov ring f... | Hexapod fixator; deftfix; external fixator; knee subluxation | null | null | null | null | null |
37,012,548 | Incremental value of radiomics-based heterogeneity to the existing risk criteria in predicting recurrence of hepatocellular carcinoma after liver transplantation. | European radiology | Eur Radiol | 33 | 9 | 10.1007/s00330-023-09591-3 | eng | 2,023 | 9 | null | 2,023 | 4 | 4 | [OBJECTIVES] The aim of the study was to evaluate the association between the radiomics-based intratumoral heterogeneity (ITH) and the recurrence risk in hepatocellular carcinoma (HCC) patients after liver transplantation (LT), and to assess its incremental to the Milan, University of California San Francisco (UCSF), M... | Hepatocellular carcinoma; Heterogeneity; Liver transplantation; Outcome; Radiomics | 1.656 | 182 | Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,023 |
37,011,886 | Frailty and Time at Home After Post-Acute Care in Skilled Nursing Facilities. | Journal of the American Medical Directors Association | J Am Med Dir Assoc | 24 | 7 | 10.1016/j.jamda.2023.02.106 | eng | 2,023 | 7 | null | 2,023 | 3 | 31 | [OBJECTIVES] To examine the association of a claims-based frailty index with time at home, defined as the number of days alive and spent out of hospital or skilled nursing facility (SNF). [DESIGN] Cohort Study. [SETTING AND PARTICIPANTS] A 5% Medicare random sample of fee-for-service beneficiaries, who had continuous p... | Frailty; post-acute care; skilled nursing facility; time at home | 1.592 | 136 | Geriatrics and Gerontology; Health Policy; Medicine; Nursing | Medicine; Nursing | 2,023 |
37,011,760 | Surgery or Endovascular Treatment in Patients with Anterior Communicating Artery Aneurysm: A Systematic Review and Meta-Analysis. | World neurosurgery | World Neurosurg | 175 | null | 10.1016/j.wneu.2023.03.111 | eng | 2,023 | 7 | null | 2,023 | 4 | 1 | [BACKGROUND AND OBJECTIVE] Although randomized controlled trials have compared surgery versus endovascular treatment for intracranial aneurysms, the literature is sparse in terms of subgroup analysis for anterior communicating artery (ACoA) aneurysm management. This systematic review and meta-analysis sought to compare... | Aneurysm; Anterior communicating artery; Clip; Coil; Endovascular; Meta-analysis; Surgery | 0.654 | 123 | Neurology; Surgery | Medicine | 2,023 |
37,011,665 | An Australian exploratory study of individual physical functioning and wellbeing of rural clients with chronic diseases whose structured exercise groups were cancelled due to social distancing requirements of the COVID-19 pandemic. | Australian journal of primary health | Aust J Prim Health | 29 | 5 | 10.1071/PY22229 | eng | 2,023 | 10 | null | null | null | null | [BACKGROUND] The primary aim of this study was to describe if there was a change in physical functioning of rural clients with chronic diseases who were unable to attend their structured exercise groups during the COVID-19 pandemic. The secondary aim was to describe their physical activity during lockdown and their wel... | null | null | null | null | null | null |
37,011,597 | Prevalence and Risk Score for Hypertonic Dehydration among Community-Dwelling Older Adults: An Analysis of the Bangkok Falls Study. | Gerontology | Gerontology | 69 | 8 | 10.1159/000530359 | eng | 2,023 | null | null | 2,023 | 4 | 3 | [INTRODUCTION] Dehydration is associated with morbidity, and many factors affect dehydration in older adults including age and medication use. This study determined the prevalence of hypertonic dehydration (HD) and factors affecting HD in older adults and developed a risk score (a set of consistent weights that assign ... | Community-dwelling older adults; Hypertonic dehydration; Risk score | 0.985 | 120 | Geriatrics and Gerontology; Aging | Biochemistry, Genetics and Molecular Biology; Medicine | 2,023 |
37,011,578 | Increased arterial stiffness and accelerated atherosclerosis in Takayasu arteritis. | Seminars in arthritis and rheumatism | Semin Arthritis Rheum | 60 | null | 10.1016/j.semarthrit.2023.152199 | eng | 2,023 | 6 | null | 2,023 | 3 | 29 | [INTRODUCTION] Cardiovascular diseases are the leading causes of morbidity and mortality in patients with Takayasu arteritis (TAK). Arterial stiffness and accelerated atherosclerosis have been reported in TAK, however, morphological changes in the arterial wall have not been adequately addressed. Shear wave elastograph... | Arterial stiffness; Atherosclerosis; Carotid artery; Shear wave elastography; Systemic lupus erythematosus; Takayasu arteritis; Ultrasonography | 1.721 | 139 | Anesthesiology and Pain Medicine; Rheumatology | Medicine | 2,023 |
37,011,526 | Efficacy, safety, and tolerability of soticlestat as adjunctive therapy for the treatment of seizures in patients with Dup15q syndrome or CDKL5 deficiency disorder in an open-label signal-finding phase II study (ARCADE). | Epilepsy behavior : EB | Epilepsy Behav | 142 | null | 10.1016/j.yebeh.2023.109173 | eng | 2,023 | 5 | null | 2,023 | 4 | 1 | [OBJECTIVE] Chromosome 15q duplication (Dup15q) syndrome and cyclin‑dependent kinase-like 5 deficiency disorder (CDD) are rare neurodevelopmental disorders associated with epileptic encephalopathies, with a lack of specifically approved treatment options. ARCADE assessed the efficacy and safety of adjunctive soticlesta... | 24S-hydroxycholesterol; CDKL5 deficiency disorder; Cholesterol 24-hydroxylase; Developmental and epileptic encephalopathies; Dup15q syndrome; Soticlestat | null | null | null | null | null |
37,010,596 | Axillary lymph node status and invasive lobular breast cancer : Analysis of the Clinical Tumor Register of the AGO Austria. | Wiener klinische Wochenschrift | Wien Klin Wochenschr | 135 | 17-18 | 10.1007/s00508-023-02162-y | eng | 2,023 | 9 | null | 2,023 | 4 | 3 | [BACKGROUND] Invasive lobular carcinoma (ILC) represents the second most common type of invasive breast cancer (BC). Although ILC generally have good prognostic properties (positive estrogen receptor, ER, low tumor grade), they are generally diagnosed at a more advanced stage. The data on the axillary lymph node status... | Axillary lymph node metastasis; Invasive breast cancer; Invasive ductal carcinoma; Invasive lobular carcinoma; Pathological node stage | 0.651 | 65 | Medicine | Medicine | 2,023 |
37,010,342 | Provider and Patient Experiences of Delays in Primary Care During the Early COVID-19 Pandemic. | Journal for healthcare quality : official publication of the National Association for Healthcare Quality | J Healthc Qual | 45 | 3 | 10.1097/JHQ.0000000000000380 | eng | null | null | null | 2,023 | 3 | 13 | [BACKGROUND] The necessary suspension of nonacute services by healthcare systems early in the COVID-19 pandemic was predicted to cause delays in routine care in the United States, with potentially serious consequences for chronic disease management. However, limited work has examined provider or patient perspectives ab... | null | null | null | null | null | null |
37,009,901 | Medical student perspectives on substance misuse education in the medical undergraduate programme: a grounded theory approach. | BMC medical education | BMC Med Educ | 23 | 1 | 10.1186/s12909-023-04145-z | eng | 2,023 | 4 | 2 | 2,023 | 4 | 2 | [BACKGROUND] Substance misuse teaching within the undergraduate medical curriculum has been underrepresented compared to more traditional medical topics. In response several national curriculum reviews such as the most recent UK department of health initiative (DOH) have identified deficiencies in substance misuse educ... | Addiction in medical school; Curriculum change; Informal learning; Student voice; Substance misuse education | 0.935 | 107 | Education; Medicine | Medicine; Social Sciences | 2,023 |
37,009,618 | Prognostic value of preoperative chemotherapy for thymic epithelial tumors: A propensity-matched analysis based on the SEER database. | Frontiers in surgery | Front Surg | 10 | null | 10.3389/fsurg.2023.1108699 | eng | 2,023 | null | null | 2,023 | 3 | 17 | [BACKGROUND] The aim of this study was to assess the impact of preoperative chemotherapy on long-term survival (≥1 month) in patients with thymic epithelial tumors (TETs) and conditions suitable for chemotherapy using data from surveillance, epidemiology, and end-result databases. [METHODS] This retrospective study con... | chemotherapy; end results program; epidemiology; preoperative chemotherapy; surveillance | 0.436 | 48 | Surgery | Medicine | 2,023 |
37,009,539 | Management and Complications of Dexamethasone Intravitreal Implant Migration Into the Anterior Chamber. | Journal of vitreoretinal diseases | J Vitreoretin Dis | 6 | 6 | 10.1177/24741264221138166 | eng | 2,022 | null | null | 2,022 | 12 | 7 | [PURPOSE] To report patient demographics, the clinical course, and visual outcomes across a case series of patients who experienced dexamethasone (DEX) intravitreal implant (Ozurdex, Allergan, Inc) migration into the anterior chamber (AC), with a focus on the corneal transplantation rate. [METHODS] In this retrospectiv... | corneal transplant; dexamethasone intravitreal implant; implant migration | null | 14 | Ophthalmology | Medicine | 2,022 |
37,009,538 | Posterior Polar Hemispheric Choroidal Dystrophy: Case Report and Presentation of Genetic Screening. | Journal of vitreoretinal diseases | J Vitreoretin Dis | 6 | 6 | 10.1177/24741264221080381 | eng | 2,022 | null | null | 2,022 | 5 | 13 | [PURPOSE] Posterior polar hemispheric choroidal dystrophy is a rare dystrophy affecting the choroid and retina with a characteristic clinical appearance that distinguishes it from a broad variety of other retinal diseases. The disease process has a morphology described in the literature that preferentially affects the ... | ERG; genetic testing; inherited retinal disease; posterior polar annular choroidal dystrophy; posterior polar hemispheric choroidal dystrophy | null | 14 | Ophthalmology | Medicine | 2,022 |
37,009,158 | The modulatory effects of gut microbes and metabolites on blood-brain barrier integrity and brain function in sepsis-associated encephalopathy. | PeerJ | PeerJ | 11 | null | 10.7717/peerj.15122 | eng | 2,023 | null | null | 2,023 | 3 | 28 | [BACKGROUND] Intestinal microbiota homeostasis and the gut-brain axis are key players associated with host health and alterations in metabolic, inflammatory, and neurodegenerative disorders. Sepsis-associated encephalopathy (SAE), which is closely associated with bacterial translocation, is a common secondary organ dys... | Microbiome-gut-brain axis; Neuroinflammation; Sepsis-associated encephalopathy; Short-chain fatty acids | 0.623 | 124 | Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience | Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience | 2,023 |
37,008,317 | Relationship between rheumatoid arthritis and cardiovascular comorbidity, causation or co-occurrence: A Mendelian randomization study. | Frontiers in cardiovascular medicine | Front Cardiovasc Med | 10 | null | 10.3389/fcvm.2023.1099861 | eng | 2,023 | null | null | 2,023 | 3 | 17 | [BACKGROUND] In recent years, the incidence rates of rheumatoid arthritis (RA) and heart disease (HD) have noticeably increased worldwide. Previous studies have found that patients with RA are more likely to develop HD, while the cause and effect have still remained elusive. In this study, Mendelian randomization (MR) ... | Mendelian randomization analysis; arrhythmia; atrial fibrillation; genome-wide association study; ischemic heart disease; myocardial infarction; rheumatoid arthritis | 0.863 | 81 | Cardiology and Cardiovascular Medicine | Medicine | 2,023 |
37,007,558 | Early administration of mucoactive agents and ventilator-free days: a propensity score-matched study. | Annals of translational medicine | Ann Transl Med | 11 | 5 | 10.21037/atm-22-4340 | eng | 2,023 | 3 | 15 | 2,023 | 2 | 24 | [BACKGROUND] Mucoactive agents are often prescribed for the management of airway secretions. However, it is unclear whether they improve respiratory outcomes in mechanically ventilated patients. [METHODS] We examined the association between the early administration of mucoactive agents in ventilated patients and increa... | Airway management; critically ill; mechanical ventilation; propensity score; ventilator-free days (VFDs) | null | null | null | null | null |
37,007,106 | A distress thermometer with a cutoff score of ≥ 6 is the optimal point to identify highly distressed patients with advanced cancer stages in resource-limited countries without palliative care services. | Frontiers in oncology | Front Oncol | 13 | null | 10.3389/fonc.2023.970164 | eng | 2,023 | null | null | 2,023 | 3 | 15 | [PURPOSE] Although the distress thermometer (DT) scale has been widely validated and used in different cancer types and settings, an optimal cutoff score of DT is not defined to screen advanced cancer patients. The study aimed to define the optimal DT's cutoff score among advanced cancer patients in resource-limited co... | advanced cancer patients; distress thermometer; healthcare system; palliative care; screening | 1.066 | 156 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,023 |
37,007,095 | Development and validation of machine learning models for predicting prognosis and guiding individualized postoperative chemotherapy: A real-world study of distal cholangiocarcinoma. | Frontiers in oncology | Front Oncol | 13 | null | 10.3389/fonc.2023.1106029 | eng | 2,023 | null | null | 2,023 | 3 | 15 | [BACKGROUND] Distal cholangiocarcinoma (dCCA), originating from the common bile duct, is greatly associated with a dismal prognosis. A series of different studies based on cancer classification have been developed, aimed to optimize therapy and predict and improve prognosis. In this study, we explored and compared seve... | AFR; DeepSurv; distal cholangiocarcinoma; individualized treatment; machine learning; post-operative chemotherapy; risk stratification | 1.066 | 156 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,023 |
37,006,723 | Investigating the Mechanism of Action of Schisandra chinensis Combined with Coenzyme Q10 in the Treatment of Heart Failure Based on PI3K-AKT Pathway. | Drug design, development and therapy | Drug Des Devel Ther | 17 | null | 10.2147/DDDT.S393995 | eng | 2,023 | null | null | 2,023 | 3 | 27 | [PURPOSE] To study the active components, drug targets and mechanism of Schisandra chinensis (S.chinensis) combined with coenzyme Q10 (CQ10) in the treatment of heart failure (HF). [METHODS] Network pharmacology combined with the gene expression omnibus chip method to analyze the main pathways by which S.chinensis comb... | Schisandra chinensis; coenzyme Q10; heart failure; mechanism validation; molecular docking; network pharmacology | 0.999 | 108 | Drug Discovery; Pharmaceutical Science; Pharmacology | Pharmacology, Toxicology and Pharmaceutics | 2,023 |
37,006,549 | Association of common mental disorders and related multimorbidity with subsequent labor market marginalization among refugee and Swedish-born young adults. | Frontiers in public health | Front Public Health | 11 | null | 10.3389/fpubh.2023.1054261 | eng | 2,023 | null | null | 2,023 | 3 | 16 | [BACKGROUND] Common mental disorders (CMDs), multimorbidity, and refugee status are associated with poor labor market outcome. Little is known about how these factors interact in young adults. [OBJECTIVE] We aimed to i) investigate whether the association of CMDs and multimorbidity with labor market marginalization (LM... | common mental disorders; disability pension; disease network; multimorbidity; refugee; unemployment | 0.895 | 119 | Public Health, Environmental and Occupational Health | Medicine | 2,023 |
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