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37,639,451
Assessing the Impact of the COVID-19 Pandemic on Training at the MD Anderson Cancer Center Anatomical Pathology Fellowship Program.
Archives of pathology & laboratory medicine
Arch Pathol Lab Med
148
5
10.5858/arpa.2023-0166-OA
eng
2,024
5
1
null
null
null
[CONTEXT] To provide high-quality, safe training during the COVID-19 pandemic, our anatomic pathology fellowship program implemented a hybrid virtual/in-person training model with supplemental digital material. [OBJECTIVE] To evaluate the impact of this model. [DESIGN] We examined Accreditation Council for Graduate Med...
null
null
null
null
null
null
37,632,771
Patients with rheumatoid arthritis presenting with mono- or oligo-arthritis and high VAS-ratings remain the most fatigued during 5 years of follow-up.
Rheumatology (Oxford, England)
Rheumatology (Oxford)
63
6
10.1093/rheumatology/kead429
eng
2,024
5
3
null
null
null
[OBJECTIVES] The severity of fatigue in RA has improved very little in recent decades, leaving a large unmet need. Fortunately, not all RA patients suffer from persistent fatigue, but the subgroup of patients who suffer the most is insufficiently recognizable at diagnosis. As disease activity is partly coupled to fatig...
RA; early arthritis; fatigue
1.721
205
Pharmacology; Rheumatology
Medicine
2,024
37,605,414
Identifying Oxidative Stress-Related Genes (OSRGs) as Potential Target for Treating Periodontitis Based on Bioinformatics Analysis.
Combinatorial chemistry high throughput screening
Comb Chem High Throughput Screen
27
8
10.2174/1386207326666230821102623
eng
2,024
null
null
null
null
null
[BACKGROUND] Periodontitis (PD) is a multifactorial inflammatory disease that is closely associated with periodontopathic bacteria. Numerous studies have demonstrated oxidative stress (OS) contributes to inflammation and is a prime factor in the development of PD. It is imperative to explore the function of newly disco...
Periodontitis; bioinformatics; chronic; oxidative stress-related genes (OSRGs); reactive oxygen species.; therapeutic targets
null
null
null
null
null
37,594,249
Exploring the Influence of E-cigarette Ad Features on Perceived Product Appeal and Use Interest Among Young Adults of Varying Tobacco-Use Behaviors.
Nicotine tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Nicotine Tob Res
26
3
10.1093/ntr/ntad150
eng
2,024
2
22
null
null
null
[INTRODUCTION] Exposure to certain features in commercial e-cigarette ads may influence e-cigarette use perceptions. This study explored the reactions toward common features in e-cigarette ads among young adults of various tobacco-use behaviors. [AIMS AND METHODS] We used data from in-depth interviews with U.S. young a...
null
null
null
null
null
null
37,586,834
Nuclear staining for pan-Trk by immunohistochemistry is highly specific for secretory carcinoma of breast: pan-Trk in various subtypes of breast carcinoma.
Journal of clinical pathology
J Clin Pathol
77
11
10.1136/jcp-2023-208989
eng
2,024
10
20
2,024
10
20
[AIMS] Secretory carcinoma of breast (SCB) typically harbours ETV6-NTRK3 gene fusion. Pan-Trk immunohistochemistry analysis (IHC) has been shown to be sensitive for SCB diagnosis. However, weak focal pan-Trk nuclear staining was previously found in 10% of non-secretory breast carcinomas. To further examine pan-Trk IHC ...
Biomarkers, Tumor; Breast Neoplasms; IMMUNOHISTOCHEMISTRY
0.802
158
Pathology and Forensic Medicine; Medicine
Medicine
2,024
37,584,344
Immunogenicity of High-Dose Versus MF59-Adjuvanted Versus Standard Influenza Vaccine in Solid Organ Transplant Recipients: The Swiss/Spanish Trial in Solid Organ Transplantation on Prevention of Influenza (STOP-FLU Trial).
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clin Infect Dis
78
1
10.1093/cid/ciad477
eng
2,024
1
25
null
null
null
[BACKGROUND] The immunogenicity of the standard influenza vaccine is reduced in solid-organ transplant (SOT) recipients, so new vaccination strategies are needed in this population. [METHODS] Adult SOT recipients from 9 transplant clinics in Switzerland and Spain were enrolled if they were 3 months after transplantatio...
immunocompromised; influenza; transplantation; vaccination
2.992
398
Infectious Diseases; Microbiology
Medicine
2,024
37,582,611
Systemic Immune-Inflammation Index is a Prognostic Predictor for Patients With Acute Ischemic Stroke Treated With Intravenous Thrombolysis.
The neurologist
Neurologist
29
1
10.1097/NRL.0000000000000508
eng
2,024
1
1
2,024
1
1
[OBJECTIVE] To investigate whether baseline systemic immune-inflammation index (SII) is associated with 3-month poor prognosis and early neurological outcomes in patients with acute ischemic stroke treated with intravenous thrombolysis. [PATIENTS AND METHODS] A total of 221 consecutive patients were enrolled in the ret...
null
0.302
68
Medicine; Neurology
Medicine
2,024
37,581,527
Preparation, Physicochemical Characterization, and Stability Study of Lippia origanoides Essential Oil-based Nanoemulsion as a Topical Delivery System.
Pharmaceutical nanotechnology
Pharm Nanotechnol
12
3
10.2174/2211738511666230815155614
eng
2,024
null
null
null
null
null
[INTRODUCTION] Fungal diseases are a priority in research, development, and health care, according to the WHO, mainly due to Candida spp. Essential oils (EOs) of the genus Lippia have demonstrated broad antimicrobial biological activity. Previous studies identified the anti-Candida potential of a thymol/p-cymene chemot...
Candida albicans.; Lippia origanoides; Nanoemulsion; essential oil; permeability; stability; thymol
null
null
null
null
null
37,562,022
Large Language Models and Artificial Intelligence: A Primer for Plastic Surgeons on the Demonstrated and Potential Applications, Promises, and Limitations of ChatGPT.
Aesthetic surgery journal
Aesthet Surg J
44
3
10.1093/asj/sjad260
eng
2,024
2
15
null
null
null
[BACKGROUND] The rapidly evolving field of artificial intelligence (AI) holds great potential for plastic surgeons. ChatGPT, a recently released AI large language model (LLM), promises applications across many disciplines, including healthcare. [OBJECTIVES] The aim of this article was to provide a primer for plastic su...
null
1.254
86
Medicine; Surgery
Medicine
2,024
37,545,269
Transcriptomic sequencing analysis of key long noncoding RNAs and mRNAs expression profiles in postoperative recurrence of hepatocellular carcinoma.
Technology and health care : official journal of the European Society for Engineering and Medicine
Technol Health Care
32
2
10.3233/THC-230123
eng
2,024
null
null
null
null
null
[BACKGROUND] Recurrence is the main cause of death in hepatocellular carcinoma (HCC) patients after liver resection. [OBJECTIVE] The long non-coding RNAs (lncRNAs) have been reported participated in progression and prognosis of HCC, however, the vital role of lncRNA in postoperative recurrence of HCC has rarely been sy...
CYP; HCC recurrence; LncRNA; RNA-seq; hepatoma postoperative recurrent model; postoperative recurrence of HCC
null
null
null
null
null
37,533,241
Aminoglycosides: Single- or Multiple-daily Dosing? An Updated Qualitative Systematic Review of Randomized Trials on Toxicity and Efficacy.
Current molecular medicine
Curr Mol Med
24
11
10.2174/1566524023666230801160452
eng
2,024
null
null
null
null
null
[INTRODUCTION] Aminoglycosides are among the first-choice antibiotics for routine clinical use. However, dose-limiting factors such as ototoxicity and nephrotoxicity are considered as serious complications of aminoglycosides. [OBJECTIVE] In this systematic review, the main goal was to investigate the efficacy and incid...
Aminoglycosides; nephrotoxicity; ototoxicity; pharmacokinetics; safety; toxicity.
null
null
null
null
null
37,523,157
Defining Magnetic Resonance Imaging Treatment Response and Remission in Crohn's Disease: A Systematic Review.
Journal of Crohn's colitis
J Crohns Colitis
18
1
10.1093/ecco-jcc/jjad125
eng
2,024
1
27
null
null
null
[BACKGROUND] Magnetic resonance imaging is increasingly used to assess treatment response in Crohn's disease clinical trials. We aimed to describe the definition of MRI response and remission as assessed by magnetic resonance enterography [MRE] to evaluate treatment efficacy in these patients. [METHODS] Electronic data...
inflammatory bowel disease; magnetic resonance enterography; magnetic resonance imaging; transmural healing
null
null
null
null
null
37,491,693
Association of atrial fibrillation with survival in patients with low-flow low-gradient aortic stenosis with preserved ejection fraction undergoing TAVI.
European heart journal. Quality of care clinical outcomes
Eur Heart J Qual Care Clin Outcomes
10
3
10.1093/ehjqcco/qcad045
eng
2,024
5
22
null
null
null
[AIMS] There is limited evidence on the prognostic significance of atrial fibrillation (AF) in patients with low flow, low-gradient aortic stenosis with preserved ejection fraction (LFLG-pEF AS). We aimed to evaluate the recovery of stroke volume after transcatheter aortic valve implantation (TAVI) and clinical outcome...
Aortic stenosis; Atrial fibrillation; Transcatheter aortic valve implantation
null
null
null
null
null
37,483,026
Atractylenolide II ameliorates myocardial fibrosis and oxidative stress in spontaneous hypertension rats.
Technology and health care : official journal of the European Society for Engineering and Medicine
Technol Health Care
32
1
10.3233/THC-220601
eng
2,024
null
null
null
null
null
[BACKGROUND] Hypertension is a well-recognized risk factor for cardiovascular, which is also a critical factor in causing myocardial fibrosis (MF). [OBJECTIVE] The study aimed to explore the effect of Atractylenolide II (ATL-II) on MF and oxidative stress in spontaneous hypertension rats (SHR). [METHODS] The body weigh...
Atractylenolide II; apoptosis; myocardial fibrosis; oxidative stress; spontaneous hypertension rats
null
null
null
null
null
37,481,706
DNA Ploidy as a Potential Adjunct Prognostic Marker of Low-Risk Prostate Cancer Progression after Radical Prostatectomy.
Urology journal
Urol J
21
2
10.22037/uj.v20i.7324
eng
2,024
3
24
2,024
3
24
[PURPOSE] Post prostatectomy PSA kinetics and General Grade Groups (GGG) are the strongest prognostic markers of biochemical recurrence (BCR) and prostate cancer (PCa)-specific mortality after radical prostatectomy. Despite having low-risk PCa, some patients will experience BCR, for some, clinically significant BCR. Th...
null
0.363
38
Urology
Medicine
2,024
37,481,694
The burden of cardiovascular disease attributable to high body mass index-an observational study.
European heart journal. Quality of care clinical outcomes
Eur Heart J Qual Care Clin Outcomes
10
2
10.1093/ehjqcco/qcad044
eng
2,024
3
1
null
null
null
[AIM] This study aims to provide a timely and comprehensive estimate of the current burden and temporal trend of cardiovascular disease (CVD) attributable to high body mass index (HBMI). [METHODS] We systematically assessed the current burden and temporal trend of CVD attributable to HBMI by calendar year, age, sex, re...
Cardiovascular Disease; Global Burden of Disease study; High Body Mass Index; Observational Study
null
null
null
null
null
37,461,344
Protective Effects of Liriodendrin on Myocardial Infarction-Induced Fibrosis in Rats via the PI3K/Akt Autophagy Pathway: A Network Pharmacology Study.
Combinatorial chemistry high throughput screening
Comb Chem High Throughput Screen
27
11
10.2174/1386207326666230717155641
eng
2,024
null
null
null
null
null
[BACKGROUND] Liriodendrin (LIR) has been reported to improve cardiac function in rats following myocardial infarction. However, its role and mechanism in reparative myocardial fibrosis remain unclear. [METHODS] In this study, a rat model of myocardial fibrosis was established via left anterior descending artery ligatio...
Autophagy; PI3K-Akt signaling pathway; liriodendrin; myocardial fibrosis; myocardial infarction (MI).; network pharmacology
null
null
null
null
null
37,460,216
Exploring the ChatGPT platform with scenario-specific prompts for vaping cessation.
Tobacco control
Tob Control
34
2
10.1136/tc-2023-058009
eng
2,025
4
1
2,025
4
1
[OBJECTIVE] To evaluate and start a discussion on the potential usefulness of applying Artificial Intelligence (AI)-driven natural language processing technology such as the ChatGPT in tobacco control efforts, specifically vaping cessation. [METHOD] Ten real-world questions about vaping cessation were selected from a R...
Cessation; ChatGPT; E-Cigarettes; Quit; Vaping
2.305
147
Health; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,024
37,455,454
The Effect of Renal Replacement Therapy in a Patient with Mercaptopurine Toxicity: Time to Revise Guidelines.
Current drug safety
Curr Drug Saf
19
2
10.2174/1574886318666230714105801
eng
2,024
null
null
null
null
null
[INTRODUCTION] Mercaptopurine, a thiopurine, is used in various disorders of immune regulation, such as autoimmune hepatitis. Thiopurine metabolism is complex with risk for overdosing, especially when metabolism is impaired by liver dysfunction. Hepatotoxicity may be due to mercaptopurine overdose and is often reversib...
Mercaptopurine toxicity; autoimmune hepatitis; concentrations; hepatotoxicity; renal replacement therapy; thiopurine toxicity.
0.295
43
Pharmacology; Pharmacology; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
37,793,795
Evaluation of effectiveness and safety of the CorPath GRX robotic system in endovascular embolization procedures of cerebral aneurysms.
Journal of neurointerventional surgery
J Neurointerv Surg
16
4
10.1136/jnis-2023-020161
eng
2,024
3
14
2,024
3
14
[BACKGROUND] Robotic-assisted neurointervention was recently introduced, with implications that it could be used to treat neurovascular diseases. [OBJECTIVE] To evaluate the effectiveness and safety of the robotic-assisted platform CorPath GRX for treating cerebral aneurysms. [METHODS] This prospective, international, ...
Aneurysm; Brain; Coil; Stent; Technology
1.634
90
Medicine; Neurology; Surgery
Medicine
2,024
37,791,984
Increased Diagnostic Accuracy of the Labial Gland Biopsy in Primary Sjögren Syndrome When Multiple Histopathological Features Are Included.
Arthritis & rheumatology (Hoboken, N.J.)
Arthritis Rheumatol
76
3
10.1002/art.42723
eng
2,024
3
null
2,024
1
9
[OBJECTIVE] The aim of this study was to evaluate the diagnostic accuracy of the labial salivary gland biopsy based on multiple histopathological features in patients with suspected primary Sjögren syndrome (pSS). [METHODS] Patients from a diagnostic sicca cohort with clinically suspected pSS who underwent a labial gla...
null
null
null
null
null
null
37,781,831
Digitizing fluid balance monitoring may offer a solution for optimizing patient care.
Technology and health care : official journal of the European Society for Engineering and Medicine
Technol Health Care
32
2
10.3233/THC-230664
eng
2,024
null
null
null
null
null
[BACKGROUND] Precise fluid balance monitoring is essential for patient treatment, as incorrect fluid balance can lead to disorders. [OBJECTIVE] This study aimed to assess the accuracy of the digital technology LICENSE (LIquid balanCE moNitoring SystEm) for fluid balance charting and compare it to the standard method (S...
Digital technology; automation; equipment design; monitoring; physiologic; water-electrolyte balance
null
null
null
null
null
37,776,542
Evaluation of Topical Off-the-Shelf Therapies to Reduce the Need to Evacuate Battlefield-Injured Warfighters.
Military medicine
Mil Med
189
7-8
10.1093/milmed/usad390
eng
2,024
7
3
null
null
null
[INTRODUCTION] Immediate evacuation of burn casualties can be challenging in austere environments, and it is predicted to be even more difficult in future multi-domain battlespaces against near-peer foes. Therefore, a need exists to treat burn wounds at the point of injury to protect the exposed injury for an extended ...
null
0.472
83
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
37,774,496
Upregulation of the NKG2D Ligand ULBP2 by JC Polyomavirus Infection Promotes Immune Recognition by Natural Killer Cells.
The Journal of infectious diseases
J Infect Dis
229
6
10.1093/infdis/jiad424
eng
2,024
6
14
null
null
null
[BACKGROUND] JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy (PML), a potentially fatal complication of severe immune suppression with no effective treatment. Natural killer (NK) cells play critical roles in defense against viral infections; however, NK-cell response to JCPyV infection remains...
JC polyomavirus; NK cell antiviral immunity; NKG2D; ULBP
2.038
282
Immunology and Allergy; Infectious Diseases
Medicine
2,024
37,773,654
Investigation on Influencing Factors and Triage Accuracy in General Clinic of Syndrome Hospital.
Alternative therapies in health and medicine
Altern Ther Health Med
30
1
null
eng
2,024
1
null
null
null
null
[OBJECTIVE] The general practice (GP) system is associated with patient-centeredness, high-quality general practitioners, and comprehensive digital information technology. Therefore, it has been promoted greatly over the recent years in China. However, there is a relatively insufficient number of patients in the genera...
null
null
78
Complementary and Alternative Medicine; Medicine
Medicine
2,024
37,753,853
Oxidative response to accumulation of trace metals in tissue of two bivalves, the Asian green mussel Perna viridis and the blood cockle Tegillarca granosa, living in Pattani Bay, Thailand.
Journal of aquatic animal health
J Aquat Anim Health
36
1
10.1002/aah.10200
eng
2,024
3
null
2,024
1
10
[OBJECTIVE] Using bivalves to indicate aquatic pollutants was favorable for discerning the negative effects of high levels of metal accumulation in tissue. We investigated the correlation between trace metal accumulation and the tissue oxidative response of two bivalves. [METHODS] The Asian green mussel Perna viridis a...
Pattani Bay; bioaccumulation; lipid peroxidation; macroconcentration; oxidative stress
null
null
null
null
null
37,748,801
Water-circulating probes significantly modify lesion length and axon damage in cooled radiofrequency ablations when compared with similar-sized standard radiofrequency probes in rats.
Regional anesthesia and pain medicine
Reg Anesth Pain Med
49
6
10.1136/rapm-2023-104554
eng
2,024
6
3
2,024
6
3
[INTRODUCTION] Preclinical research demonstrated water-cooled radiofrequency (CRF) ablations have a significant impact on structural and functional changes compared to standard radiofrequency (SRF) ablations. Clinical procedures utilizing RF to treat chronic pain conditions also show sustained functional outcomes. We h...
Animal Experimentation; CHRONIC PAIN; Pain Management; Peripheral Nerve Injuries
1.411
130
Anesthesiology and Pain Medicine; Medicine
Medicine
2,024
37,743,172
Disease burden, comorbidities and antecedents of chronic cough phenotypes in Australian adults.
Pulmonology
Pulmonology
31
1
10.1016/j.pulmoe.2023.08.003
eng
2,025
12
31
2,024
11
11
[BACKGROUND AND OBJECTIVES] While adult chronic cough has high burden, its phenotypes, particularly those without aetiologically related underlying conditions, are understudied. We investigated the prevalence, lung function and comorbidities of adult chronic cough phenotypes. [METHODS] Data from 3608 participants aged ...
Chronic cough; Comorbidity; Cough phenotypes; Lung function
1.434
43
Pulmonary and Respiratory Medicine
Medicine
2,024
37,738,461
Concomitant exposure to air pollution, green space and noise, and risk of myocardial infarction: a cohort study from Denmark.
European journal of preventive cardiology
Eur J Prev Cardiol
31
1
10.1093/eurjpc/zwad306
eng
2,024
1
5
null
null
null
[AIMS] The three correlated environmental exposures (air pollution, road traffic noise, and green space) have all been associated with the risk of myocardial infarction (MI). The present study aimed to analyse their independent and cumulative association with MI. [METHODS AND RESULTS] In a cohort of all Danes aged 50 o...
Air pollution; Cohort study; Epidemiology; Green space; Myocardial infarction; Traffic noise
2.119
130
Cardiology and Cardiovascular Medicine; Epidemiology
Medicine
2,024
37,734,729
Differences in Strength and Fatigue Resistance of Scapular Protractors and Retractors Between Symptomatic and Asymptomatic Dyskinesis.
Journal of athletic training
J Athl Train
59
8
10.4085/1062-6050-0092.23
eng
2,024
8
1
null
null
null
[CONTEXT] Scapular dyskinesis is a shoulder dysfunction that can be asymptomatic or associated with pain or weakness. Reduced strength and fatigue resistance of the scapular protractor and retractor muscles that stabilize the scapula might contribute to dyskinesis. [OBJECTIVES] To determine the strength and fatigue res...
closed chain exercise; isokinetic exercise; scapular dyskinesis; shoulder injuries
1.106
139
Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,024
37,728,908
Prenatal Exposure to Nonpersistent Environmental Chemicals and Postpartum Depression.
JAMA psychiatry
JAMA Psychiatry
81
1
10.1001/jamapsychiatry.2023.3542
eng
2,024
1
1
null
null
null
[IMPORTANCE] Postpartum depression (PPD) affects up to 20% of childbearing individuals, and a significant limitation in reducing its morbidity is the difficulty in modifying established risk factors. Exposure to synthetic environmental chemicals found in plastics and personal care products, such as phenols, phthalates,...
null
null
null
null
null
null
37,724,649
Externally validated prediction models for pre-eclampsia: systematic review and meta-analysis.
Ultrasound in obstetrics gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
Ultrasound Obstet Gynecol
63
5
10.1002/uog.27490
eng
2,024
5
null
null
null
null
[OBJECTIVE] This systematic review and meta-analysis aimed to evaluate the performance of existing externally validated prediction models for pre-eclampsia (PE) (specifically, any-onset, early-onset, late-onset and preterm PE). [METHODS] A systematic search was conducted in five databases (MEDLINE, EMBASE, Emcare, CINA...
eclampsia; external validation; prediction; prognostic
null
null
null
null
null
37,713,267
Improved early outcome prediction by MRI-based 3D tumor volume assessment in patients with CNS lymphomas.
Neuro-oncology
Neuro Oncol
26
2
10.1093/neuonc/noad177
eng
2,024
2
2
null
null
null
[BACKGROUND] Central nervous system lymphomas (CNSL) display remarkable clinical heterogeneity, yet accurate prediction of outcomes remains challenging. The IPCG criteria are widely used in routine practice for the assessment of treatment response. However, the value of the IPCG criteria for ultimate outcome prediction...
CNS lymphoma; MRI-based 3D volumetry; circulating tumor DNA; composite biomarker; improved early outcome prediction
6.974
178
Cancer Research; Neurology; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
37,711,133
Comparative Efficacy of Endogenous Stem Cells Recruiting Hydrogels and Stem Cell-loaded Hydrogels in Knee Cartilage Regeneration: A Meta- analysis.
Current stem cell research therapy
Curr Stem Cell Res Ther
19
7
10.2174/1574888X19666230914123443
eng
2,024
null
null
null
null
null
[BACKGROUND] Cartilage defects remain a challenge in diseases such as osteoarthritis (OA) and fractures. Scientists have explored the use of hydrogels in conjunction with stem cell technology as a tissue engineering method to treat cartilage defects in joints. In recent years, research into hydrogels containing stem ce...
Animal trial; cartilage regeneration; heterogeneity.; hydrogel; meta-analysis; stem cell
null
null
null
null
null
37,690,115
Endogenous Glucose Production in Patients With Glycogen Storage Disease Type Ia Estimated by Oral D-[6,6-2H2]-glucose.
The Journal of clinical endocrinology and metabolism
J Clin Endocrinol Metab
109
2
10.1210/clinem/dgad537
eng
2,024
1
18
null
null
null
[CONTEXT] Glycogen storage disease type Ia (GSDIa) is an inborn metabolic disorder characterized by impaired endogenous glucose production (EGP). Monitoring of patients with GSDIa is prioritized because of ongoing treatment developments. Stable isotope tracers may enable reliable EGP monitoring. [OBJECTIVE] The aim of ...
diet; glycogen storage disease type Ia; monitoring; precision medicine; stable isotopes
2.183
400
Biochemistry; Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
37,671,784
LATE RECURRENCE OF RETINAL DETACHMENT: Incidence, Clinical Features, and Surgical Outcomes.
Retina (Philadelphia, Pa.)
Retina
44
1
10.1097/IAE.0000000000003924
eng
2,024
1
1
null
null
null
[PURPOSE] To describe and evaluate demographics, clinical features, prognostic factors, rate of success of surgery, incidence, and visual outcomes in patients with a late recurrence of rhegmatogenous retinal detachment over a 10-year period at a large tertiary referral eye center. [METHODS] A retrospective, observation...
null
1.018
149
Medicine; Ophthalmology
Medicine
2,024
37,669,005
Random Forest for Predicting Treatment Response to Radioiodine and Thyrotropin Suppression Therapy in Patients With Differentiated Thyroid Cancer But Without Structural Disease.
The oncologist
Oncologist
29
1
10.1093/oncolo/oyad252
eng
2,024
1
5
null
null
null
[BACKGROUND] We aimed to develop a machine-learning model for predicting treatment response to radioiodine (131I) therapy and thyrotropin (TSH) suppression therapy in patients with differentiated thyroid cancer (DTC) but without structural disease, based on pre-treatment information. [PATIENTS AND METHODS] Overall, 597...
131I therapy; DTC without structural disease; TSH suppression therapy; random forest; thyroglobulin
2.329
199
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
37,897,240
Syndecan-1 levels predict septic shock in critically ill patients with COVID-19.
Transactions of the Royal Society of Tropical Medicine and Hygiene
Trans R Soc Trop Med Hyg
118
3
10.1093/trstmh/trad077
eng
2,024
3
4
null
null
null
[BACKGROUND] The clinical picture of coronavirus disease 2019 (COVID-19)-associated sepsis is similar to that of sepsis of other aetiologies. The present study aims to analyse the role of syndecan-1 (SDC-1) as a potential predictor of septic shock in critically ill patients with COVID-19. [METHODS] This is a prospectiv...
COVID-19; endothelium; septic shock; vascular biomarkers; vasopressors
0.644
120
Infectious Diseases; Medicine; Parasitology; Public Health, Environmental and Occupational Health
Immunology and Microbiology; Medicine
2,024
37,882,356
Comparative study of a point-of-care test and an enzyme-linked immunosorbent assay (ELISA) for infliximab levels.
Scandinavian journal of gastroenterology
Scand J Gastroenterol
59
2
10.1080/00365521.2023.2269456
eng
2,024
null
null
2,024
1
30
[BACKGROUND] Proactive therapeutic drug monitoring (TDM) is often challenged by long turnaround time when using enzyme-linked immunosorbent assays (ELISAs), especially when analyses are centralised. Point-of-care tests (POCTs) allow rapid assessments, but data on their agreement with existing in-house methodologies are...
ELISA; IBD; infliximab; point-of-care test; therapeutic drug monitoring
0.689
133
Gastroenterology
Medicine
2,024
37,873,911
Potential Neuroprotective Strategies using Smart Drug Delivery Systems for Alzheimer's Disease.
Infectious disorders drug targets
Infect Disord Drug Targets
24
3
10.2174/0118715265254985231012065058
eng
2,024
null
null
null
null
null
[BACKGROUND] Alzheimer's disease (AD) is the most common neurological disorder, affecting more than 50 million individuals worldwide and causing gradual but progressive cognitive decline. The rising cost of medical treatment is mostly attributable to AD. There are now mainly a few slightly symptomatic therapeutic optio...
Alzheimer's disease; neurological disorder.; patents; pathophysiology; smart drug delivery; targeting of Alzheimer's disease
null
null
null
null
null
37,861,050
In-vitro Augmentation of Mesenchymal Stem Cells by Using Adult Bovine Serum.
Current stem cell research therapy
Curr Stem Cell Res Ther
19
9
10.2174/011574888X260118230927050143
eng
2,024
null
null
null
null
null
[BACKGROUND] Umbilical cord mesenchymal stem cells (UC-MSCs) are increasingly being utilized for immune-related disease therapies due to their low immunogenicity. However, the primary culture of UC-MSCs requires the supplementation of serum in the growth medium, which has posed a challenge due to ethical issues related...
Stem cells; adult bovine serum; fetal bovine serum; mesenchymal stem cells; umbilical cord.; viability
null
null
null
null
null
37,855,739
Acute leukemia with cytogenetically cryptic FGFR1 rearrangement and lineage switch during therapy: A case report and literature review.
American journal of clinical pathology
Am J Clin Pathol
161
2
10.1093/ajcp/aqad135
eng
2,024
2
1
null
null
null
[OBJECTIVES] Myeloid/lymphoid neoplasms with FGFR1 rearrangement are a rare group of neoplasms that share features of eosinophilia and lineage promiscuity. First, we described a challenging case of acute leukemia with lineage switch and cytogenetically cryptic FGFR1. Second, we aimed to systemically review this phenome...
FGFR1; RUNX1; acute leukemia; lineage switch; myeloid/lymphoid neoplasms with eosinophilia
0.754
146
Pathology and Forensic Medicine; Medicine
Medicine
2,024
37,851,954
The Determinants of Elevated Pathobiological Determination of Atherosclerosis in Youth Risk Score in Perinatally HIV-Infected Adolescents in South Africa.
Journal of acquired immune deficiency syndromes (1999)
J Acquir Immune Defic Syndr
95
1
10.1097/QAI.0000000000003304
eng
2,024
1
1
null
null
null
[BACKGROUND] Youth living with perinatally acquired HIV infection (YLPHIV) are at risk of developing atherosclerotic cardiovascular disease. [METHODS] We determined the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) coronary arteries (CA) and abdominal aorta (AA) risk scores among YLPHIV who are ≥15 ye...
null
1.04
176
Infectious Diseases; Pharmacology
Medicine
2,024
37,837,204
Systematic Review of Injuries and Chronic Musculoskeletal Pain Among High-speed Boat Operators.
Military medicine
Mil Med
189
3-4
10.1093/milmed/usad377
eng
2,024
2
27
null
null
null
[INTRODUCTION] High-speed boat operators constitute a population at risk of work-related injuries and disabilities. This review aimed to summarize the available knowledge on workplace-related injuries and chronic musculoskeletal pain among high-speed boat operators. [MATERIALS AND METHODS] In this systematic review, we...
null
0.472
83
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
37,833,042
Hemophagocyte morphology and hypertriglyceridemia correlate with diagnosis of hemophagocytic lymphohistiocytosis in patients with bone marrow hemophagocytes.
American journal of clinical pathology
Am J Clin Pathol
161
2
10.1093/ajcp/aqad131
eng
2,024
2
1
null
null
null
[OBJECTIVES] To investigate laboratory and bone marrow findings that can help predict a diagnosis of hemophagocytic lymphohistiocytosis (HLH) for patients who have demonstrated hemophagocytes (HPCs) in the bone marrow. [METHODS] A total of 57 cases from 48 patients with HPCs present on bone marrow examination were incl...
HLH; granulocyte; hemophagocyte; hemophagocytic lymphohistiocytosis; triglyceride
0.754
146
Pathology and Forensic Medicine; Medicine
Medicine
2,024
37,821,210
Comparison of intestinal microbes and metabolites in active VKH versus acute anterior uveitis associated with ankylosing spondylitis.
The British journal of ophthalmology
Br J Ophthalmol
109
3
10.1136/bjo-2023-324125
eng
2,025
2
24
2,025
2
24
[BACKGROUND] It has been reported that the gut microbiome is involved in the pathogenesis of uveitis, but the specific pathogenic microbes and metabolites in different types of uveitis are still unclear. [METHODS] Microbiome and metabolites were detected using 16S ribosomal DNA and LC‒MS/MS (liquid chromatography tande...
Inflammation; Iris; Microbiology; Vitreous
1.806
185
Cellular and Molecular Neuroscience; Ophthalmology; Sensory Systems
Medicine; Neuroscience
2,024
37,815,181
In-silico Investigation of Ginseng Phytoconstituents as Novel Therapeutics Against MAO-A.
Current computer-aided drug design
Curr Comput Aided Drug Des
20
5
10.2174/0115734099266270230925090023
eng
2,024
null
null
null
null
null
[BACKGROUND] Ginseng (Panax ginseng) is a herb of medicinal and nutritional importance. Ginseng has been used since ancient times for the treatment of numerous ailments as it has many therapeutic properties. Several phytoconstituents are present in Panax ginseng that possess a variety of beneficial pharmacological prop...
ADME; MAO-A; diseases; ginesinoside; ginseng; mental health; molecular docking; plants; stachyose.
null
null
null
null
null
37,815,179
Pre-clinical Aspects and Contemporary Treatments of Parkinson's Disease.
CNS neurological disorders drug targets
CNS Neurol Disord Drug Targets
23
8
10.2174/0118715273258646230920074421
eng
2,024
null
null
null
null
null
[BACKGROUND] After Alzheimer's disease, the second slot for the most common neurodegenerative disease, is occupied by Parkinson's disease. The symptoms of Parkinson's are classified as motor symptoms and non-motor symptoms. Motor symptoms involve rigidity, tremors, bradykinesia, and postural instability. Non-motor symp...
animal models; biomarkers; neuropharmacology; pathophysiology; regenerative therapies.; treatment
null
null
null
null
null
37,812,788
Septic and febrile kidney stone presentations during the COVID-19 pandemic What is the effect of reduced access to care during pandemic restrictions?
Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Can Urol Assoc J
18
1
10.5489/cuaj.8450
eng
2,024
1
null
null
null
null
[INTRODUCTION] During the early stages of the COVID-19 pandemic, hospitals shifted their resources and focus toward COVID-19 care and non-deferrable conditions. Renal colic is one of the most common urologic presentations to the emergency department (ED). In our study, we examined whether there was an increase in septi...
null
null
null
null
null
null
37,804,123
Incidence of Dementia and Alzheimer's Disease, Genetic Susceptibility, and Grip Strength Among Older Adults.
The journals of gerontology. Series A, Biological sciences and medical sciences
J Gerontol A Biol Sci Med Sci
79
3
10.1093/gerona/glad224
eng
2,024
3
1
null
null
null
[BACKGROUND] Grip strength has prognostic value for aging-related health outcomes. Whether the associations of grip strength with the risk of dementia and Alzheimer's disease (AD) vary by the genetic risk of AD and related dementias (ADD) is unknown. [METHODS] This study included 148 659 older adults of white British a...
Dementia; Genetic susceptibility; Grip strength; Older adults; UK Biobank
1.334
230
Geriatrics and Gerontology; Aging
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
37,971,959
Opioid tapering in older cancer survivors does not increase psychiatric or drug hospitalization rates.
Journal of the National Cancer Institute
J Natl Cancer Inst
116
4
10.1093/jnci/djad241
eng
2,024
4
5
null
null
null
[BACKGROUND] Opioid tapering in the general population is linked to increases in hospitalizations or emergency department visits related to psychiatric or drug-related diagnoses. Cancer survivors represent a unique population with different opioid indications, prescription patterns, and more frequent follow-up care. Th...
null
5.703
394
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
37,968,940
Dispersal from Africa to the Neotropics was followed by multiple transitions across Neotropical biomes facilitated by frugivores.
Annals of botany
Ann Bot
133
5-6
10.1093/aob/mcad175
eng
2,024
5
10
null
null
null
[BACKGROUND AND AIM] Plant disjunctions have fascinated biogeographers and ecologists for a long time. We use tribe Bocageeae (Annonaceae), a predominantly Neotropical plant group distributed across several present-day Neotropical biomes and with an African-American disjunction, to investigate long-distance dispersal m...
Amazonia; Atlantic Forest; Boreotropics; divergence times; phylogenomics
1.294
215
Plant Science
Agricultural and Biological Sciences
2,024
37,966,910
The predictive accuracy of cardiovascular disease risk prediction tools in inflammatory arthritis and psoriasis: an observational validation study using the Clinical Practice Research Datalink.
Rheumatology (Oxford, England)
Rheumatology (Oxford)
63
12
10.1093/rheumatology/kead610
eng
2,024
12
1
null
null
null
[OBJECTIVES] Cardiovascular risk prediction tools developed for the general population often underperform for individuals with RA, and their predictive accuracy are unclear for other inflammatory conditions that also have increased cardiovascular risk. We investigated the performance of QRISK-3, the Framingham Risk Sco...
ankylosing spondylitis; cardiovascular risk prediction; psoriasis; psoriatic arthritis; rheumatoid arthritis
1.721
205
Pharmacology; Rheumatology
Medicine
2,024
37,957,912
Exploring the Synergistic Effect of Sildenafil and Green Tea Polyphenols on Breast Cancer Stem Cell-like Cells and their Parental Cells: A Potential Novel Therapeutic Approach.
Anti-cancer agents in medicinal chemistry
Anticancer Agents Med Chem
24
4
10.2174/0118715206276925231107060329
eng
2,024
2
22
null
null
null
[BACKGROUND] Many cancer studies have intensely focused on the role of diet, among other factors involved in cancer establishment. The positive effect of green tea polyphenols (GTP) on controlling breast cancer cells has been reported in several studies. Cancer stem cell-like cells (CSC-LCs) possessing self-renewal, me...
Breast cancer; CSC-LCs; MCF-7; MDA-MB-231; combination therapy.; green tea polyphenols
null
null
null
null
null
37,957,859
4D-QSAR and MIA-QSAR Studies of Aminobenzimidazole Derivatives as Fourth-generation EGFR Inhibitors.
Medicinal chemistry (Shariqah (United Arab Emirates))
Med Chem
20
2
10.2174/0115734064258994231106052633
eng
2,024
null
null
null
null
null
[BACKGROUND] The epidermal growth factor receptor (EGFR) protein has been intensively studied as a therapeutic target for non-small cell lung cancer (NSCLC). The aminobenzimidazole derivatives as the fourth-generation EGFR inhibitors have achieved promising results and overcame EGFR mutations at C797S, del19 and T790M ...
4D-QSAR; EGFR inhibitors; MIA-QSAR; NSCLC.; aminobenzimidazole derivatives; molecular dynamic simulation
null
null
null
null
null
37,956,408
Functional assay for assessment of pathogenicity of BAP1 variants.
Human molecular genetics
Hum Mol Genet
33
5
10.1093/hmg/ddad193
eng
2,024
2
18
null
null
null
[BACKGROUND] Pathogenic germline variants in BRCA1-Associated Protein 1 (BAP1) cause BAP1 tumor predisposition syndrome (BAP1-TPDS). Carriers run especially a risk of uveal (UM) and cutaneous melanoma, malignant mesothelioma, and clear cell renal carcinoma. Approximately half of increasingly reported BAP1 variants lack...
BAP1; BAP1-TPDS; HAP1; uveal melanoma; variant interpretation
null
null
null
null
null
37,952,220
A Feasibility Randomized Trial Evaluating Safe Peds: A Virtual Reality Training Program to Teach Children When to Cross Streets Safely.
Journal of pediatric psychology
J Pediatr Psychol
49
4
10.1093/jpepsy/jsad083
eng
2,024
4
15
null
null
null
[OBJECTIVE] Injury as pedestrians is a leading contributor to childhood deaths. This study evaluated the effectiveness of Safe Peds, a fully immersive virtual reality training program to teach children when to cross street safely, with the focus on a number of foundational skills and practicing these in traffic situati...
behavioral training; children; pedestrian; virtual reality
1.052
143
Pediatrics, Perinatology and Child Health; Developmental and Educational Psychology
Medicine; Psychology
2,024
37,950,859
Device-measured physical activity and cardiometabolic health: the Prospective Physical Activity, Sitting, and Sleep (ProPASS) consortium.
European heart journal
Eur Heart J
45
6
10.1093/eurheartj/ehad717
eng
2,024
2
7
null
null
null
[BACKGROUND AND AIMS] Physical inactivity, sedentary behaviour (SB), and inadequate sleep are key behavioural risk factors of cardiometabolic diseases. Each behaviour is mainly considered in isolation, despite clear behavioural and biological interdependencies. The aim of this study was to investigate associations of f...
Cardiometabolic outcomes; Cohort consortium; Compositional data analysis; Physical activity; Sedentary behaviour; Sleep; Standing
null
null
null
null
null
37,950,564
Incidence, predictors, and prognostic impact of rehospitalization after transcatheter aortic valve implantation.
European heart journal. Quality of care clinical outcomes
Eur Heart J Qual Care Clin Outcomes
10
5
10.1093/ehjqcco/qcad067
eng
2,024
8
8
null
null
null
[AIMS] Despite rehospitalization being common after transcatheter aortic valve implantation (TAVI), an in-depth analysis on this topic is missing. This study sought to report on the incidence, predictors, and prognostic impact of rehospitalization within 1 year following TAVI. [METHODS AND RESULTS] All consecutive pati...
Aortic valve stenosis; Predictors; Prognostic impact; Rehospitalization; Transcatheter aortic valve implantation
null
null
null
null
null
37,946,558
Whole-Genome Sequencing Predicting Phenotypic Antitubercular Drug Resistance: Meta-analysis.
The Journal of infectious diseases
J Infect Dis
229
5
10.1093/infdis/jiad480
eng
2,024
5
15
null
null
null
[BACKGROUND] For simultaneous prediction of phenotypic drug susceptibility test (pDST) for multiple antituberculosis drugs, the whole genome sequencing (WGS) data can be analyzed using either a catalog-based approach, wherein 1 causative mutation suggests resistance, (eg, World Health Organization catalog) or noncatalo...
Mycobacterium infections; DNA sequencing analysis; antibacterial agent; systematic review
2.038
282
Immunology and Allergy; Infectious Diseases
Medicine
2,024
37,944,024
Multi-omics analysis revealed the regulation mode of intratumor microorganisms and microbial signatures in gastrointestinal cancer.
Carcinogenesis
Carcinogenesis
45
3
10.1093/carcin/bgad078
eng
2,024
3
11
null
null
null
[OBJECTIVE] Gastrointestinal cancer is one of the most common malignant tumors in the world, and its incidence rate is always high. In recent years, research has shown that microorganisms may play a broad role in the diagnosis, pathogenesis, and treatment of cancer. [METHODS] In this study, samples were first classifie...
null
0.978
227
Medicine; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
37,938,036
Effect of Extracerebral Contamination on Near-infrared Spectroscopy as Revealed during Organ Donation: A Prospective Observational Study in Brain-dead Organ Donors.
Anesthesiology
Anesthesiology
140
2
10.1097/ALN.0000000000004828
eng
2,024
2
1
null
null
null
[BACKGROUND] Near-infrared spectroscopy (NIRS) has been utilized widely in anesthesia and intensive care to monitor regional cerebral oxygen saturation (rScO2). A normal oxygenation of extracerebral tissues may overlay and thereby mask cerebral desaturations, a phenomenon known as extracerebral contamination. The autho...
null
null
null
null
null
null
37,936,542
Risk of Hypertensive Disorders and Preterm Birth in Pregnant Women With Systemic Vasculitides: A Nationwide Population-Based Cohort Study.
Arthritis rheumatology (Hoboken, N.J.)
Arthritis Rheumatol
76
3
10.1002/art.42747
eng
2,024
3
null
2,024
1
19
[OBJECTIVE] Even though systemic vasculitides (SVs) affect primarily patients over 50 years of age, they can occur among women of childbearing age. Preterm birth (PTB) and hypertensive disorders are frequent complications of pregnancy in SVs. This study aims to evaluate the risk of hypertensive disorders and PTB among ...
null
null
null
null
null
null
37,936,257
Silver Lining Study: Missileer Fatigue Mitigation During 2020 Coronavirus Pandemic.
Military medicine
Mil Med
189
5-6
10.1093/milmed/usad415
eng
2,024
5
18
null
null
null
[INTRODUCTION] The U.S. Air Force's Intercontinental Ballistic Missile (ICBM) force stands ready to launch weapons 365 days per year. Since its inception, missileers vigilantly operate launch consoles on a 3-day cycle: minimum 24-hour alert-shift/24-hour travel-admin/24-hour off, leading to concerns that health, morale...
null
0.472
83
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
37,934,758
Crohn's Disease Mortality and Ambient Air Pollution in New York City.
Inflammatory bowel diseases
Inflamm Bowel Dis
30
10
10.1093/ibd/izad243
eng
2,024
10
3
null
null
null
[BACKGROUND] The worldwide increase in Crohn's disease (CD) has accelerated alongside rising urbanization and accompanying decline in air quality. Air pollution affects epithelial cell function, modulates immune responses, and changes the gut microbiome composition. In epidemiologic studies, ambient air pollution has a...
air pollution; inflammatory bowel disease
1.78
183
Gastroenterology; Immunology and Allergy
Medicine
2,024
37,931,982
Perioperative opioid prescribing and iatrogenic opioid use disorder and overdose: a state-of-the-art narrative review.
Regional anesthesia and pain medicine
Reg Anesth Pain Med
49
8
10.1136/rapm-2023-104944
eng
2,024
8
5
2,024
8
5
[BACKGROUND/IMPORTANCE] Considerable attention has been paid to identifying and mitigating perioperative opioid-related harms. However, rates of postsurgical opioid use disorder (OUD) and overdose, along with associated risk factors, have not been clearly defined. [OBJECTIVE] Evaluate the evidence connecting perioperat...
Analgesics, Opioid; Opioid-Related Disorders; Pain Management
1.411
130
Anesthesiology and Pain Medicine; Medicine
Medicine
2,024
37,929,977
WITHDRAWN: Snare traction-assisted method during endoscopic resection for gastric submucosal tumors: a single center case series.
Revista espanola de enfermedades digestivas
Rev Esp Enferm Dig
116
10
10.17235/reed.2023.10034/2023
eng
2,024
10
null
null
null
null
[BACKGROUND] Endoscopic resection (ER) of gastric submucosal tumors (G-SMTs) is challenging due to the difficulty of exposure. Traction-assisted ER has been shown to provide better outcomes than traditional endoscopic operation by exposing the dissection plane. In this study, we investigated the efficacy and safety of ...
null
null
null
null
null
null
37,922,304
Association of Urine Albumin to Creatinine Ratio With Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus.
The Journal of clinical endocrinology and metabolism
J Clin Endocrinol Metab
109
4
10.1210/clinem/dgad645
eng
2,024
3
15
null
null
null
[CONTEXT] The urinary albumin to creatinine ratio (UACR) is a widely used indicator of albuminuria and has predictive value for adverse cardiovascular events. [OBJECTIVE] To evaluate the correlation between the UACR and the risk of developing major adverse cardiovascular events (MACEs) and total mortality in patients w...
major adverse cardiovascular events; total mortality; type 2 diabetes mellitus; urinary albumin to creatinine ratio
2.183
400
Biochemistry; Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
37,910,641
SCLEROMYXEDEMA ASSOCIATED WITH MACULAR EDEMA AND RETINAL HEMORRHAGE.
Retinal cases brief reports
Retin Cases Brief Rep
19
1
10.1097/ICB.0000000000001510
eng
2,025
1
1
null
null
null
[PURPOSE] We discuss a case of macular edema and retinal hemorrhage associated with scleromyxedema. [METHODS] A case report is presented. [RESULTS] A 64-year-old man with history of deep vein thrombosis and pulmonary embolism presented with new-onset rash in the setting of switching anticoagulation treatments. He devel...
null
null
null
null
null
null
37,909,430
Estimating the Size of the Hidden Population of COVID-19.
Infectious disorders drug targets
Infect Disord Drug Targets
24
2
10.2174/0118715265255039231018113634
eng
2,024
null
null
null
null
null
[INTRODUCTION] An asymptomatic population has the same infection as symptomatic individuals, so these individuals can unknowingly spread the virus. It is not possible to predict the rate of epidemic growth by considering only the identified isolated or hospitalized population. In this study, we want to estimate the siz...
COVID-19; estimating; hidden population; outbreaks globally.; patients; respondent-driven sampling
null
null
null
null
null
37,909,385
Using Electronic Health Records and Linked Claims Data to Assess New Medication Use and Primary Nonadherence in Rheumatology Patients.
Arthritis care research
Arthritis Care Res (Hoboken)
76
4
10.1002/acr.25269
eng
2,024
4
null
2,024
1
18
[OBJECTIVE] The objective of this study was to determine the proportion of new medication prescriptions observed in electronic health records (EHR) that represent true incident medication use, accounting for undocumented previous prescriptions (prevalent medication use) and failure to initiate treatment (primary nonadh...
null
null
null
null
null
null
37,907,488
Evaluation of Enhanced Cytotoxicity Effect of Repurposed Drug Simvastatin/Thymoquinone Combination against Breast Cancer Cell Line.
Cardiovascular hematological agents in medicinal chemistry
Cardiovasc Hematol Agents Med Chem
22
3
10.2174/0118715257259037231012182741
eng
2,024
null
null
null
null
null
[INTRODUCTION] Repurposing of drugs for their anticancer potential is gaining a lot of importance in drug discovery. [AIMS] The present study aims to explore the potential of Simvastatin (SIM), a drug used in the treatment of high cholesterol, and Thymoquinone (Nigella Sativa) (THY) for its anti-cancer activity on brea...
Breast cancer; cell apoptosis; cell cycle arrest; drug combination; drug repurposing; mevalonate pathway.; simvastatin
null
null
null
null
null
38,040,450
Incremental value of machine learning for risk prediction in tetralogy of Fallot.
Heart (British Cardiac Society)
Heart
110
8
10.1136/heartjnl-2023-323296
eng
2,024
3
22
2,024
3
22
[OBJECTIVE] Machine learning (ML) can facilitate prediction of major adverse cardiovascular events (MACEs) in repaired tetralogy of Fallot (rTOF). We sought to determine the incremental value of ML above expert clinical judgement for risk prediction in rTOF. [METHODS] Adult congenital heart disease (ACHD) clinicians (≥...
Magnetic Resonance Imaging; Quality of Health Care; Risk Factors; Tetralogy of Fallot
1.781
214
Cardiology and Cardiovascular Medicine
Medicine
2,024
38,032,624
Hypoglossal Nerve Stimulation and Cardiovascular Outcomes for Patients With Obstructive Sleep Apnea: A Randomized Clinical Trial.
JAMA otolaryngology-- head neck surgery
JAMA Otolaryngol Head Neck Surg
150
1
10.1001/jamaoto.2023.3756
eng
2,024
1
1
null
null
null
[IMPORTANCE] Sham-controlled trials are needed to characterize the effect of hypoglossal nerve stimulation (HGNS) therapy on cardiovascular end points in patients with moderate-severe obstructive sleep apnea (OSA). [OBJECTIVE] To determine the effect of therapeutic levels of HGNS, compared to sham levels, on blood pres...
null
null
null
null
null
null
38,031,906
Breaking boundaries: laparoscopic and endoscopic collaboration in appendectomy.
Revista espanola de enfermedades digestivas
Rev Esp Enferm Dig
116
12
10.17235/reed.2023.10092/2023
eng
2,024
12
null
null
null
null
[BACKGROUND] The combination of endoscopy and laparoscopic assistance is gaining attention due to its minimally invasive approach and the potential to improve the safety of surgical treatment for potential malignant tumors at the base of the appendix. [METHODS] Initially, we attempted an endoscopic resection for a pati...
null
null
null
null
null
null
38,031,795
Potential Association of The Pathogenic Kruppel-like Factor 14 (KLF14) and Adiponectin (ADIPOQ) SNVs with Susceptibility to T2DM.
Endocrine, metabolic immune disorders drug targets
Endocr Metab Immune Disord Drug Targets
24
9
10.2174/0118715303258744231117064253
eng
2,024
null
null
null
null
null
[AIM] To evaluate the associations of the pathogenic variants in Kruppel-like Factor 14 (KLF 14) and Adiponectin (ADIPOQ) with susceptibility to type 2 diabetes mellitus (T2DM). [BACKGROUND] Type 2 diabetes mellitus (T2DM) is a pandemic metabolic disease characterized by increased blood sugar and caused by resistance t...
KLF-14 rs972283 SNV; KLF-14.; Single nucleotide variations (SNVs); adiponectin ADIPOQ-rs266729; type 2 diabetes
null
null
null
null
null
38,031,777
Kenaf Seed Cysteine Protease (KSCP) Inhibits the Intrinsic Pathway of the Blood Coagulation Cascade and Platelet Aggregation.
Current protein peptide science
Curr Protein Pept Sci
25
5
10.2174/0113892037265109231114065204
eng
2,024
null
null
null
null
null
[BACKGROUND] Thrombosis is the key event that obstructs the flow of blood throughout the circulatory system, leading to stroke, myocardial infarction and severe cardiovascular complications. Currently, available antithrombotic drugs trigger several life-threatening side effects. [INTRODUCTION] Antithrombotic agents fro...
Anticoagulant; antithrombotic; clot hydrolysis; electrophoresis; kenaf seed cysteine protease; platelet aggregation.
null
null
null
null
null
38,030,959
Fetal premature atrial contractions: natural course, risk factors and adverse outcome.
Ultrasound in obstetrics gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
Ultrasound Obstet Gynecol
63
5
10.1002/uog.27546
eng
2,024
5
null
null
null
null
[OBJECTIVES] Fetal premature atrial contractions (PAC) are usually benign but may be associated with congenital heart defect (CHD) and tachyarrhythmia, which in turn carry a risk of cardiac failure and fetal death. We aimed to explore the frequency of adverse outcome and to identify risk factors for tachyarrhythmia in ...
congenital heart defect; fetal arrhythmia; fetal echocardiography; premature atrial contractions; supraventricular tachycardia
null
null
null
null
null
38,016,180
Exposure to airborne mycotoxins: the riskiest working environments and tasks.
Annals of work exposures and health
Ann Work Expo Health
68
1
10.1093/annweh/wxad070
eng
2,024
1
8
null
null
null
[OBJECTIVES] There is growing interest in the role of airborne mycotoxins in occupational environments, however, their impact on human health still remains poorly investigated. This review aims to provide a comprehensive analysis of the existing literature on the occurrence of inhalable mycotoxins in working environmen...
inhalation; molds; mycotoxin; occupational exposure; risk assessment; toxicity; working task
null
null
null
null
null
38,014,801
Concussion Symptomatology by Symptom Resolution Time in US High School Athletes: Findings From the National Athletic Treatment, Injury and Outcomes Network High School Surveillance Program (NATION-SP).
Journal of athletic training
J Athl Train
59
7
10.4085/1062-6050-0201.23
eng
2,024
7
1
null
null
null
[CONTEXT] Concussions incurred during high school athletics are a significant health concern, and studies examining concussions with a symptom resolution time (SRT) of 15 to 28 days have been limited. [OBJECTIVE] To compare concussions that had an SRT of 15 to 28 days with concussions that had an SRT of greater than 28...
adolescent; head injuries; mild traumatic brain injury; pediatric; youth sports
1.106
139
Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,024
38,014,796
Visual Disruption and Neuromechanics During Landing-Cutting in Individuals With Chronic Ankle Instability.
Journal of athletic training
J Athl Train
59
8
10.4085/1062-6050-0379.23
eng
2,024
8
1
null
null
null
[CONTEXT] Individuals with chronic ankle instability (CAI) demonstrate altered movement patterns when their vision is disturbed during simple tasks, such as single-legged standing and walking. However, it remains unclear whether visual disruption by stroboscopic glasses alters movement patterns during landing-cutting m...
ankle sprains; stroboscopic glasses; visual reliance
1.106
139
Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,024
38,014,534
Scutellarin Alleviates Diabetic Retinopathy via the Suppression of Nucleotide-Binding Oligomerization Domain (NOD)-Like Receptor Pyrin Domain Containing Protein 3 Inflammasome Activation.
Current eye research
Curr Eye Res
49
2
10.1080/02713683.2023.2273777
eng
2,024
2
null
2,024
1
18
[PURPOSE] Diabetic retinopathy, a prevalent complication of diabetes, represents the leading cause of vision loss and blindness among middle-aged and elderly populations. Recent research has demonstrated the ameliorating effects of scutellarin on diabetes-associated complications such as diabetic retinopathy and type 2...
Diabetic retinopathy; NLRP3 inflammasome; inflammation; scutellarin; streptozotocin
0.693
94
Ophthalmology; Cellular and Molecular Neuroscience; Sensory Systems
Medicine; Neuroscience
2,024
38,011,533
Characterization of skin barrier defects using infrared spectroscopy in patients with atopic dermatitis.
Clinical and experimental dermatology
Clin Exp Dermatol
49
5
10.1093/ced/llad416
eng
2,024
4
23
null
null
null
[BACKGROUND] Atopic dermatitis (AD) is characterized by skin barrier defects that are often measured by biophysical tools that observe the functional properties of the stratum corneum (SC). [OBJECTIVES] To employ in vivo infrared spectroscopy alongside biophysical measurements to analyse changes in the chemical composi...
null
0.692
92
Dermatology
Medicine
2,024
38,001,045
Changes in the swallowing pattern and tongue posture during the transition from deciduous to mixed dentition-a longitudinal ultrasonography study.
European journal of orthodontics
Eur J Orthod
46
1
10.1093/ejo/cjad066
eng
2,024
1
1
null
null
null
[BACKGROUND] Given the importance that swallowing pattern and tongue posture might have in the aetiology of malocclusion, it appears important to be aware of the physiological changes of tongue function and its posture. [OBJECTIVES] The study aimed to assess changes of the swallowing pattern and tongue posture during t...
deciduous dentition; mixed dentition; swallowing pattern; tongue posture; ultrasonography
1.012
105
Orthodontics
Dentistry
2,024
38,001,042
Differential Impact of Smoking on Methylome and Transcriptome in Crohn's Disease and Ulcerative Colitis.
Inflammatory bowel diseases
Inflamm Bowel Dis
30
6
10.1093/ibd/izad268
eng
2,024
6
3
null
null
null
[BACKGROUND] Smoking is an environmental factor that differentially impacts Crohn's disease (CD) and ulcerative colitis (UC). The mechanism of impact of smoking on disease risk and clinical outcomes remains to be established. [METHODS] This study used a prospective cohort of patients with CD or UC. Self-reported smokin...
RNA-seq; epigenetics; methylation; smoking; ulcerative colitis
1.78
183
Gastroenterology; Immunology and Allergy
Medicine
2,024
37,983,734
COVID-19 Pandemic is Associated With Increased Prevalence of GERD and Decreased GERD-related Quality of Life: Analysis From 9800 Participants in the Indonesian GERD-Q Study.
Journal of clinical gastroenterology
J Clin Gastroenterol
58
4
10.1097/MCG.0000000000001923
eng
2,024
4
1
2,024
4
1
[INTRODUCTION] The prevalence of gastroesophageal reflux disease (GERD) is expected to increase during the pandemic due to unexpected, sudden lifestyle changes such as decreased physical activity and worsening mental conditions. Here, we aim to explore the difference in the prevalence of GERD and GERD-related quality o...
null
0.993
135
Gastroenterology
Medicine
2,024
37,983,048
Remote Carbon Monoxide Capture via REDCap: Evaluation of an Integrated Mobile Application.
Nicotine tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Nicotine Tob Res
26
6
10.1093/ntr/ntad230
eng
2,024
5
22
null
null
null
[INTRODUCTION] To improve the feasibility of remote biochemical verification of smoking status, our team developed "COast," a mobile app integrated with REDCap that allows a research participant to complete self-report research assessments and provide a breath sample via the iCOQuit Smokerlyzer for the purposes of carb...
null
null
null
null
null
null
37,982,451
The Marketing and Perceptions of Non-Tobacco Blunt Wraps on Twitter.
Substance use misuse
Subst Use Misuse
59
4
10.1080/10826084.2023.2280572
eng
2,024
null
null
2,024
2
8
[OBJECTIVE] Non-tobacco blunt wraps (N-TBWs), which entered the marketplace in 2017, are being promoted as an alternative to traditional TBWs (e.g., cigarillos) for blunt smoking. The lack of studies on these novel products warrants an investigation. This study was the first to explore blunt smokers' perceptions about ...
Non-tobacco blunt wraps; cannabis regulation; harm reduction; machine learning; social media; tobacco regulation; topic modeling
null
null
null
null
null
37,977,193
Brief Report: Incidence and Management of Complex Kidney Situations Among On-Demand and Daily HIV Pre-Exposure Prophylaxis Users.
Journal of acquired immune deficiency syndromes (1999)
J Acquir Immune Defic Syndr
95
3
10.1097/QAI.0000000000003346
eng
2,024
3
1
null
null
null
[BACKGROUND] We evaluated complex pre-exposure prophylaxis (PrEP) situations linked to kidney issues in a cohort of on-demand and daily PrEP users. [SETTING] We conducted a single-center retrospective cohort study in France including all PrEP users who received a tenofovir disoproxil (TD)-emtricitabine (FTC) prescripti...
null
1.04
176
Infectious Diseases; Pharmacology
Medicine
2,024
37,976,098
Regional and temporal differences in the associations between cardiovascular disease and its classic risk factors: an analysis of 49 cohorts from 11 European countries.
European journal of preventive cardiology
Eur J Prev Cardiol
31
5
10.1093/eurjpc/zwad359
eng
2,024
3
27
null
null
null
[AIMS] The regional and temporal differences in the associations between cardiovascular disease (CVD) and its classic risk factors are unknown. The current study examined these associations in different European regions over a 30-year period. [METHODS AND RESULTS] The study sample comprised 553 818 individuals from 49 ...
Cardiovascular disease; Coronary heart disease; Europe; Risk factor; Stroke
2.119
130
Cardiology and Cardiovascular Medicine; Epidemiology
Medicine
2,024
37,973,197
Outcome data from 15 years of cystic fibrosis newborn screening in a large UK region.
Archives of disease in childhood
Arch Dis Child
109
4
10.1136/archdischild-2023-325955
eng
2,024
3
19
2,024
3
19
[BACKGROUND] The West Midlands Newborn Bloodspot Screening Laboratory is one of 16 in the UK and serves two tertiary paediatric cystic fibrosis (CF) centres (Staffordshire Children's Hospital at Royal Stoke and Birmingham Children's Hospital). CF newborn bloodspot screening (NBS) in this region started in November 2006...
cystic fibrosis; epidemiology
0.972
169
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,091,605
ACUTE ATROPHIC EVOLUTION OF DRUSENOID PIGMENT EPITHELIUM DETACHMENT AFTER PHOTOBIOMODULATION.
Retinal cases brief reports
Retin Cases Brief Rep
19
2
10.1097/ICB.0000000000001529
eng
2,025
3
1
null
null
null
[PURPOSE] The aim of this study was to report the acute onset of macular atrophy soon after photobiomodulation (PBM) administration in a patient with intermediate age-related macular degeneration. [METHODS] Optical coherence tomography was performed in the study eye before and after PBM. [RESULTS] A patient with drusen...
null
null
null
null
null
null
38,090,864
Prosthetic Limb Attachment via Electromagnetic Attraction Through a Closed Skin Envelope.
IEEE transactions on bio-medical engineering
IEEE Trans Biomed Eng
71
5
10.1109/TBME.2023.3342652
eng
2,024
5
null
2,024
4
22
[OBJECTIVE] Current socket-based methods of prosthetic limb attachment are responsible for many of the dominant problems reported by persons with amputation. In this work, we introduce a new paradigm for attachment via electromagnetic attraction between a bone-anchored ferromagnetic implant and an external electromagne...
null
null
null
null
null
null
38,088,437
Residual leaks following percutaneous left atrial appendage occlusion and outcomes: a meta-analysis.
European heart journal
Eur Heart J
45
3
10.1093/eurheartj/ehad828
eng
2,024
1
14
null
null
null
[BACKGROUND AND AIMS] Residual leaks are not infrequent after left atrial appendage occlusion. However, there is still uncertainty regarding their prognostic implications. The aim of this study is to evaluate the impact of residual leaks after left atrial appendage occlusion. [METHODS] A literature search was conducted...
Left atrial appendage occlusion; Meta-analysis; Peri-device leak; Prognosis; Thromboembolism
null
null
null
null
null
38,086,734
Persistence and recovery of dinotefuran in eastern hemlock (Tsuga canadensis) foliage and twigs by UPLC-MS/MS and ELISA.
Pest management science
Pest Manag Sci
80
4
10.1002/ps.7926
eng
2,024
4
null
2,024
1
31
[BACKGROUND] Dinotefuran, a systemic neonicotinoid insecticide, is approved for control of hemlock woolly adelgid (HWA) (Adelges tsugae Annand), an invasive sap-feeding insect that can kill eastern hemlocks (Tsuga canadensis). Dinotefuran is highly water soluble, facilitating more rapid translocation and HWA control th...
Adelges tsugae; Tsuga canadensis; dinotefuran; hemlock woolly adelgid control; insecticide residue analysis; pest management
null
null
null
null
null
38,085,236
Sympathicotomy for isolated facial blushing: long-term follow-up of a randomized trial.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Eur J Cardiothorac Surg
65
3
10.1093/ejcts/ezad414
eng
2,024
3
1
null
null
null
[OBJECTIVES] Thoracoscopic sympathicotomy may be an effective treatment for disabling facial blushing in selected patients. Short- and mid-term results are good but very long-term results are scarce in the medical literature and there is no knowledge which extent of sympathicotomy is better long-term for isolated facia...
Facial blushing; Hyperhidrosis; Sympathicotomy
1.033
158
Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,024
38,073,353
Modern robotics platform associated with reduced 90-day complications in hospital setting.
Technology and health care : official journal of the European Society for Engineering and Medicine
Technol Health Care
32
5
10.3233/THC-231198
eng
2,024
null
null
null
null
null
[BACKGROUND] Early complications in total knee arthroplasty (TKA) associated with modern robotics platforms integrated with digital balancing technology have not been investigated. [OBJECTIVE] The objective was to compare 90-day complication rates between a manual technique and a modern robotic-assisted ligament balanc...
ASC; Total knee arthroplasty; ambulatory surgical center; complications; hospital; robotics; soft tissue
null
null
null
null
null
38,073,151
Invasive fusariosis in patients with leukaemia in the era of mould-active azoles: increasing incidence, frequent breakthrough infections and lack of improved outcomes.
The Journal of antimicrobial chemotherapy
J Antimicrob Chemother
79
2
10.1093/jac/dkad377
eng
2,024
2
1
null
null
null
[OBJECTIVES] Historically, patients with leukaemia and invasive fusariosis (IF) have experienced poor outcomes in the setting of persistent immunosuppression. Herein, we retrospectively reviewed the incidence, presentation and outcomes of IF that are scarcely studied in contemporary cohorts of leukaemia patients. [METH...
null
1.209
229
Infectious Diseases; Microbiology; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,071,540
Using crowdsourcing at an academic conference to develop STI testing messaging for public dissemination.
Sexually transmitted infections
Sex Transm Infect
100
2
10.1136/sextrans-2023-056002
eng
2,024
2
19
2,024
2
19
[OBJECTIVES] We provide a guide to conducting a crowdsourcing activity at an international sexually transmitted infection (STI) conference to design public messaging about STI testing and disseminating that messaging via social media. [METHODS] A speaker gave a presentation at a conference plenary session on the concep...
Chlamydia Infections; Communication; gonorrhoea
1.019
115
Dermatology; Infectious Diseases
Medicine
2,024
38,064,609
Effectiveness and Safety of Low-Dose Radiotherapy in Eosinophilic Lymphoid Granuloma.
Alternative therapies in health and medicine
Altern Ther Health Med
30
8
null
eng
2,024
8
null
null
null
null
[OBJECTIVE] To investigate the efficacy and safety of low-dose radiotherapy in treating eosinophilic lymphoid granuloma. [METHOD] This study included a total of 20 patients diagnosed with eosinophilic lymphoid granuloma. All patients underwent low-dose three-dimensional conformal intensity-modulated radiotherapy for th...
null
null
78
Complementary and Alternative Medicine; Medicine
Medicine
2,024