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38,064,596
Clinical Effects of Exercise Combined with Respiratory Training in the Rehabilitation Treatment of Patients with Chronic Obstructive Pulmonary Disease.
Alternative therapies in health and medicine
Altern Ther Health Med
30
8
null
eng
2,024
8
null
null
null
null
[OBJECTIVE] This study aimed to evaluate the impact of exercise and respiratory training for chronic obstructive pulmonary disease (COPD) patients on specific COPD-related outcomes, such as lung function, exercise capacity, and patient prognosis. [METHODS] This work had a retrospective design. The subjects of this stud...
null
null
78
Complementary and Alternative Medicine; Medicine
Medicine
2,024
38,061,768
Frequency and types of errors in clinician-composed death certificates for patients with or without autopsy in a hospital population.
Journal of public health (Oxford, England)
J Public Health (Oxf)
46
1
10.1093/pubmed/fdad255
eng
2,024
2
23
null
null
null
[BACKGROUND] Death certificate (DC) errors are common. At our institution, all deaths have a preliminary death certificate (PDC) written by a clinician and then revised by a pathologist prior to the clinician signing the final death certificate (FDC). In autopsy cases, the FDC is signed by the pathologist who performs ...
autopsy; cause of death; death certificates; death certification
0.953
103
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
38,061,030
Bone turnover change after randomized switch from tenofovir disoproxil to tenofovir alafenamide fumarate in men with HIV.
AIDS (London, England)
AIDS
38
4
10.1097/QAD.0000000000003811
eng
2,024
3
15
2,024
2
1
[OBJECTIVE] Bone loss in people with HIV (PWH) is poorly understood. Switching tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF) has yielded bone mineral density (BMD) increases. PETRAM (NCT#:03405012) investigated whether BMD and bone turnover changes correlate. [DESIGN] Open-label, randomized control...
null
1.209
233
Infectious Diseases; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
38,057,159
Effect of Anamorelin, a Ghrelin Receptor Agonist, on Muscle and Bone in Adults With Osteosarcopenia.
The Journal of clinical endocrinology and metabolism
J Clin Endocrinol Metab
109
3
10.1210/clinem/dgad702
eng
2,024
2
20
null
null
null
[CONTEXT] Anamorelin, a ghrelin receptor agonist known to stimulate the pulsatile release of GH from the pituitary, has the potential to improve musculoskeletal health in adults with osteosarcopenia. [OBJECTIVE] To determine the effect of anamorelin treatment for 1 year on muscle mass and strength and on biochemical ma...
CTX; P1NP; anamorelin; bone turnover; ghrelin receptor agonist; leg strength; osteosarcopenia
2.183
400
Biochemistry; Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,055,778
The value of plasma metanephrine measurements during adrenal vein sampling.
Endocrine connections
Endocr Connect
13
2
10.1530/EC-23-0300
eng
2,024
2
1
2,024
1
12
[OBJECTIVE] The assessment of primary aldosteronism incorporates adrenal vein sampling (AVS) to lateralize aldosterone excess. Current adrenal vein sampling protocols rely on concurrent cortisol measurements to assess successful cannulation and lateralization and may be inaccurate in the setting of autonomous cortisol ...
adrenal vein sampling; metanephrines; primary aldosteronism
0.905
50
Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,050,064
Lessons From the COVID-19 Pandemic Response Implementation: A Case Study of South Sudan and Sierra Leone.
Global health, science and practice
Glob Health Sci Pract
12
Suppl 1
10.9745/GHSP-D-23-00180
eng
2,024
2
20
2,024
2
20
[INTRODUCTION] The COVID-19 pandemic caused havoc to health systems worldwide and in countries that already had weak health systems. There are lessons to be learned that could contribute to improved response preparedness to future public health emergencies, but there is little documentation on best practices in fragile...
null
0.713
48
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,024
38,050,056
Balanced crystalloids (RInger's lactate) versus normal Saline in adults with diabetic Ketoacidosis in the Emergency Department (BRISK-ED): a pilot randomised controlled trial.
Emergency medicine journal : EMJ
Emerg Med J
41
2
10.1136/emermed-2023-213290
eng
2,024
1
22
2,024
1
22
[BACKGROUND] Current diabetic ketoacidosis (DKA) treatment guidelines recommend using normal saline (NS); however, NS may delay DKA resolution by causing more hyperchloremic metabolic acidosis compared with balanced crystalloids. This study's objective was to determine the feasibility of a future multicentred randomise...
clinical management; diabetes; emergency department
0.789
100
Emergency Medicine; Critical Care and Intensive Care Medicine; Medicine
Medicine
2,024
38,050,029
2023 EULAR recommendations for the management of fatigue in people with inflammatory rheumatic and musculoskeletal diseases.
Annals of the rheumatic diseases
Ann Rheum Dis
83
10
10.1136/ard-2023-224514
eng
2,024
9
30
2,024
9
30
[OBJECTIVES] Fatigue is prevalent in people with inflammatory rheumatic and musculoskeletal diseases (I-RMDs) and recognised as one of the most challenging symptoms to manage. The existence of multiple factors associated with driving and maintaining fatigue, and the evidence about what improves fatigue has led to a mul...
health services research; rehabilitation; therapeutics
5.731
300
Biochemistry, Genetics and Molecular Biology; Immunology; Immunology and Allergy; Rheumatology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,024
38,048,611
Rheumatoid arthritis, quantitative parenchymal lung features and mortality among smokers.
Rheumatology (Oxford, England)
Rheumatology (Oxford)
64
1
10.1093/rheumatology/kead645
eng
2,025
1
1
null
null
null
[OBJECTIVES] There have been limited investigations of the prevalence and mortality impact of quantitative CT (QCT) parenchymal lung features in RA. We examined the cross-sectional prevalence and mortality associations of QCT features, comparing RA and non-RA participants. [METHODS] We identified participants with and ...
emphysema; interstitial lung abnormalities; quantitative imaging; rheumatoid arthritis
1.721
205
Pharmacology; Rheumatology
Medicine
2,024
38,048,058
TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Clin Cancer Res
30
4
10.1158/1078-0432.CCR-23-2566
eng
2,024
2
16
null
null
null
[PURPOSE] Mechanisms of primary resistance to inhibitors of the programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) signaling axis in non-small cell lung cancer (NSCLC) are still poorly understood. While some studies suggest the involvement of trophoblast cell surface antigen 2 (TROP2) in modulating tumor ...
null
4.8
392
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,043,007
Subcutaneous fat predicts bone metastasis in breast cancer: A novel multimodality-based deep learning model.
Cancer biomarkers : section A of Disease markers
Cancer Biomark
39
3
10.3233/CBM-230219
eng
2,024
null
null
null
null
null
[OBJECTIVES] This study explores a deep learning (DL) approach to predicting bone metastases in breast cancer (BC) patients using clinical information, such as the fat index, and features like Computed Tomography (CT) images. [METHODS] CT imaging data and clinical information were collected from 431 BC patients who und...
Breast cancer; bone metastases; deep learning; local binary pattern (LBP) features; subcutaneous fat
null
null
null
null
null
38,041,846
Characteristics of delirium among COVID-19 patients.
Bratislavske lekarske listy
Bratisl Lek Listy
125
1
10.4149/BLL_2024_009
eng
2,024
null
null
null
null
null
[OBJECTIVE] This study estimated delirium incidence in Slovak COVID-19 patients, explored treatment associations and examined the impact on hospitalization and mortality. [BACKGROUND] The COVID-19 pandemic caused by SARS-CoV-2 has significantly affected global health. Delirium, a severe form of acute brain dysfunction,...
COVID-19; cognition psychiatric comorbidities of COVID-19.; delirium; psychiatric drugs
null
null
null
null
null
38,041,839
Impact of autologous stem cell transplantation (ASCT) on progression free survival (PFS) in newly diagnosed multiple myeloma patients (NDMM) with high risk cytogenetic abnormalities.
Bratislavske lekarske listy
Bratisl Lek Listy
125
1
10.4149/BLL_2024_002
eng
2,024
null
null
null
null
null
[OBJECTIVES] ASCT has been considered the standard of care for younger patients with NDMM, however, not all the studies published so far have uniformly demonstrated the complete superiority of ASCT over chemotherapy at standard doses. A systematic review and meta-analysis of randomized studies has shown a significant b...
autologous stem cell transplantation; multiple myeloma; overall survival high-risk cytogenetics.; progression free survival
null
null
null
null
null
38,158,723
Vitamin D and vitamin K status in postmenopausal women with normal and low bone mineral density.
Clinical chemistry and laboratory medicine
Clin Chem Lab Med
62
7
10.1515/cclm-2023-1443
eng
2,024
6
25
2,024
1
1
[OBJECTIVES] Vitamin D and K are believed to promote bone health, but existing evidence is controversial. This study aimed to measure several metabolites of both vitamins by liquid chromatography tandem mass spectrometry (LC-MS/MS) in a cohort of postmenopausal women with low and normal bone mineral density (BMD). [MET...
bone mineral density; bone turnover markers; postmenopausal women; vitamin D; vitamin K
0.952
127
Biochemistry; Medicine; Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,157,438
State-related Electroencephalography Microstate Complexity during Propofol- and Esketamine-induced Unconsciousness.
Anesthesiology
Anesthesiology
140
5
10.1097/ALN.0000000000004896
eng
2,024
5
1
null
null
null
[BACKGROUND] Identifying the state-related "neural correlates of consciousness" for anesthetics-induced unconsciousness is challenging. Spatiotemporal complexity is a promising tool for investigating consciousness. The authors hypothesized that spatiotemporal complexity may serve as a state-related but not drug-related...
null
null
null
null
null
null
38,157,294
Associations Between Blood Concentrations of Sex Hormones and Physical Function in Community-Dwelling Older Women: A Prospective Cohort Study.
The journals of gerontology. Series A, Biological sciences and medical sciences
J Gerontol A Biol Sci Med Sci
79
4
10.1093/gerona/glad287
eng
2,024
4
1
null
null
null
[BACKGROUND] Blood concentrations of testosterone and estrone tend to increase in women aged ≥70 years, whereas concentrations of their precursor hormone dehydroepiandrosterone decline. It is unknown whether these changes influence physical function. We investigated whether concentrations of these hormones were associa...
dehydroepiandrosterone; estrone; grip strength; testosterone; women
1.334
230
Geriatrics and Gerontology; Aging
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,155,466
Role of Complement-dependent Cytotoxicity Crossmatch and HLA Typing in Solid Organ Transplant.
Reviews on recent clinical trials
Rev Recent Clin Trials
19
1
10.2174/0115748871266738231218145616
eng
2,024
null
null
null
null
null
[BACKGROUND] Solid organ transplantation is a life-saving medical operation that has progressed greatly because of developments in diagnostic tools and histocompatibility tests. Crossmatching for complement-dependent cytotoxicity (CDC) and human leukocyte antigen (HLA) typing are two important methods for checking graf...
CDC crossmatching; HLA; Solid organ; artificial intelligence; bone marrow.; transplantation
null
null
null
null
null
38,154,477
Clinical Characteristics and Risk of Hypoxemia Development in Women Infected with SARS-CoV-2 during Pregnancy.
Yonsei medical journal
Yonsei Med J
65
1
10.3349/ymj.2023.0270
eng
2,024
1
null
null
null
null
[PURPOSE] There is limited information on the clinical characteristics and prognosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy. The clinical features and risk factors for hypoxemia development were investigated in pregnant women with coronavirus disease-2019 (COVID-19). ...
COVID-19; Pregnancy; Severity of Illness Index; risk factors; severe acute respiratory syndrome coronavirus 2
0.827
78
Medicine
Medicine
2,024
38,154,475
Association between Obesity and Heart Failure and Related Atrial Fibrillation: Patient-Level Data Comparisons of Two Cohort Studies.
Yonsei medical journal
Yonsei Med J
65
1
10.3349/ymj.2023.0264
eng
2,024
1
null
null
null
null
[PURPOSE] Heart failure (HF) and atrial fibrillation (AF) frequently coexist, with over 50% patients with HF having AF, while one-third of those with AF develop HF. Differences in obesity-mediated association between HF and HF-related AF among Asians and Europeans were evaluated. [MATERIALS AND METHODS] Using the Korea...
Obesity; atrial fibrillation; body mass index; heart failure
0.827
78
Medicine
Medicine
2,024
38,153,883
Exploring the influence of density-dependence and weather on the spatial and temporal variation in common vole (Microtus arvalis) abundance in Castilla y León, NW Spain.
Pest management science
Pest Manag Sci
80
11
10.1002/ps.7954
eng
2,024
11
null
2,024
1
20
[BACKGROUND] The common vole has invaded the agroecosystems of northwestern Spain, where outbreaks cause important crop damage and management costs. Little is yet known about the factors causing or modulating vole fluctuations. Here, we used 11 years of vole abundance monitoring data in 40 sites to study density-depend...
common vole; population dynamics; spatiotemporal fluctuations; weather modulation
null
null
null
null
null
38,150,386
Systematic Literature Review: Ability of the IBDQ-32 to Detect Meaningful Change in Ulcerative Colitis Health Indicators.
Inflammatory bowel diseases
Inflamm Bowel Dis
30
11
10.1093/ibd/izad282
eng
2,024
11
4
null
null
null
[PURPOSE] Previous reviews produced weak evidence regarding the responsiveness of the Inflammatory Bowel Disease Questionnaire (IBDQ-32) to changes in ulcerative colitis (UC) health indicators. This systematic review and meta-analysis provide an updated synthesis on IBDQ-32 responsiveness. [METHODS] A systematic litera...
IBDQ; responsiveness; ulcerative colitis
1.78
183
Gastroenterology; Immunology and Allergy
Medicine
2,024
38,146,835
High prevalence of venous thrombotic events in Cushing's syndrome: data from ERCUSYN and details in relation to surgery.
European journal of endocrinology
Eur J Endocrinol
190
1
10.1093/ejendo/lvad176
eng
2,024
1
3
null
null
null
[OBJECTIVE] The aim of this study was to evaluate the prevalence of venous thromboembolism (VTE) in patients included in the European Registry on Cushing's syndrome (ERCUSYN), compare their clinical characteristics with those who did not develop VTE and identify risk factors for VTE. [DESIGN] A retrospective observatio...
Cushing's syndrome; ERCUSYN; risk factors; venous thromboembolism
1.81
179
Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,146,054
A framework for assessing the impacts of land-use/cover change and climate change on wheat productivity under 1.5 and 2.0 °C warming at watershed scale.
Journal of the science of food and agriculture
J Sci Food Agric
104
6
10.1002/jsfa.13237
eng
2,024
4
null
2,024
1
8
[BACKGROUND] Irrigation is used extensively to enhance grain production and ensure food security. Many studies have used crop models and global climate models to study the variation of irrigated crop yield in the context of climate change. But most considered the influence of direct climate change but neglected the inf...
Wei River basin; crop model; hydrological model; wheat yield
null
null
null
null
null
38,145,414
The outcomes of considering goals of care in medication reviews for older adults: a systematic review.
Expert review of clinical pharmacology
Expert Rev Clin Pharmacol
17
1
10.1080/17512433.2023.2286321
eng
2,024
1
null
2,024
1
23
[INTRODUCTION] This is a systematic review of prescribing, clinical, patient-reported, and health utilization outcomes of goal-directed medication reviews in older adults. [METHODS] A systematic review was conducted using MEDLINE, EMBASE, SCOPUS and CINAHL databases to identify studies examining outcomes of goal-direct...
Medication review; clinical pharmacology; geriatrics; goal; goals of care; medication optimization; personal goals; polypharmacy
1.072
67
Medicine; Pharmacology; Pharmacology, Toxicology and Pharmaceutics
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,143,385
Validating the Fatigue Scale for Motor and Cognitive Function (FSMC) in chronic stroke.
NeuroRehabilitation
NeuroRehabilitation
54
2
10.3233/NRE-230189
eng
2,024
null
null
null
null
null
[BACKGROUND] Post-stroke fatigue can manifest as both physical and mental fatigue. The Fatigue Scale for Motor and Cognitive Functions (FSMC) evaluates fatigue on the motor and cognitive domains separately, however, the psychometric properties of this measure in stroke have not been reported. [OBJECTIVE] To determine t...
Physical fatigue; exhaustion; mental fatigue; pathological fatigue; perceived effort; tiredness
null
null
null
null
null
38,141,035
Accuracy, acceptability and feasibility of photography for use in trachoma surveys: a mixed methods study in Tanzania.
International health
Int Health
16
4
10.1093/inthealth/ihad111
eng
2,024
7
2
null
null
null
[BACKGROUND] Photography could be used to train individuals to diagnose trachomatous inflammation-follicular (TF) as trachoma prevalence decreases and to ensure accurate field TF grading in trachoma prevalence surveys. We compared photograph and field TF grading and determined the acceptability and feasibility of eyeli...
Chlamydia trachomatis; Tanzania; acceptability; feasibility; photography; trachoma
0.89
48
Health; Medicine; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,024
38,140,962
Using Military Screening Questions to Anonymously Recruit Post-9/11 Era Service Members and Veterans Using Online Survey Methods.
Military medicine
Mil Med
189
5-6
10.1093/milmed/usad469
eng
2,024
5
18
null
null
null
[INTRODUCTION] The ability to collect data on posttraumatic reactions following military sexual trauma is impacted by data collection methods, such that under-reporting can occur when data are believed to be identifiable. This may be especially true for topics that are sensitive, including sexual trauma. Ensuring parti...
null
0.472
83
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
38,133,615
Guselkumab demonstrates long-term efficacy and maintenance of treatment response postwithdrawal in systemic treatment-naïve patients and nonresponders to fumaric acid esters: results from parts II and III of a randomized active-comparator-controlled phase IIIb trial (POLARIS).
The British journal of dermatology
Br J Dermatol
191
1
10.1093/bjd/ljad523
eng
2,024
6
20
null
null
null
[BACKGROUND] The anti-interleukin-23 antibody guselkumab (GUS) demonstrated favourable week 24 efficacy and safety over fumaric acid esters (FAE) in systemic treatment-naïve patients with moderate-to-severe plaque psoriasis (study part I). [OBJECTIVES] To compare, in study part II, the sustainability of treatment respo...
null
2.459
214
Dermatology; Medicine
Medicine
2,024
38,127,643
Cigarette Prices and Disparities in Smoking Cessation in the United States.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Nicotine Tob Res
26
8
10.1093/ntr/ntad254
eng
2,024
7
22
null
null
null
[INTRODUCTION] Achieving cessation in people with established smoking patterns remains a challenge. Increasing cigarette prices has been one of the most successful strategies for lowering smoking rates. The extent to which it has remained effective in encouraging cessation among adults in recent years and how the effec...
null
null
null
null
null
null
38,127,642
Causes of death among international travellers in Peru, 2017 to 2021.
Journal of travel medicine
J Travel Med
31
1
10.1093/jtm/taad163
eng
2,024
1
28
null
null
null
[BACKGROUND] The wellbeing and safety of international tourists is a paramount concern for governments and stakeholders. Mortality among travellers and the causes of death serve as a significant metric of destination safety. We describe the epidemiology and causes of death among international travellers in Peru. [METHO...
America; Prevention; communicable diseases; injuries; non-communicable diseases
1.562
77
Infectious Diseases; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
38,124,458
Prognostic value of gut microbe-generated metabolite phenylacetylglutamine in patients with heart failure.
European journal of heart failure
Eur J Heart Fail
26
2
10.1002/ejhf.3111
eng
2,024
2
null
2,024
1
25
[AIM] Phenylacetylglutamine (PAGln) is a phenylalanine-derived metabolite produced by gut microbiota with mechanistic links to heart failure (HF)-relevant phenotypes. We sought to investigate the prognostic value of PAGln in patients with stable HF. [METHODS AND RESULTS] Fasting plasma PAGln levels were measured by sta...
Heart failure; Microbiome; Phenylacetylglutamine
null
null
null
null
null
38,124,177
Braid stability after flow diverter treatment of intracranial aneurysms: a systematic review and meta-analysis.
Journal of neurointerventional surgery
J Neurointerv Surg
17
3
10.1136/jnis-2023-021120
eng
2,025
2
14
2,025
2
14
[BACKGROUND] The aim of this study was to evaluate the overall rates of braid changes associated with flow diverter (FD) treatment for intracranial aneurysms (IAs). Additionally, we sought to provide an overview of the currently reported definitions related to these complications. [METHODS] A systematic search was cond...
aneurysm; complication; device; flow diverter; intervention
1.634
90
Medicine; Neurology; Surgery
Medicine
2,024
38,123,971
Top 25 Most-Cited Articles on Robotic-Assisted Lumbar Spine Surgery.
International journal of spine surgery
Int J Spine Surg
18
1
10.14444/8565
eng
2,024
3
4
2,024
3
4
[BACKGROUND] Robot-guided lumbar spine surgery has evolved rapidly with evidence to support its utility and feasibility compared with conventional freehand and fluoroscopy-based techniques. The objective of this study was to assess trends among the top 25 most-cited articles pertaining to robotic-guided lumbar spine su...
clinical outcomes; lumbar; navigation; pedicle screw; robotic spine surgery
0.748
40
Surgery; Orthopedics and Sports Medicine
Medicine
2,024
38,123,516
Quantifying hospital-associated costs, and accompanying travel costs and productivity losses, before and after withdrawing TNF-α inhibitors in juvenile idiopathic arthritis.
Rheumatology (Oxford, England)
Rheumatology (Oxford)
63
SI2
10.1093/rheumatology/kead688
eng
2,024
9
1
null
null
null
[OBJECTIVE] To quantify differences in hospital-associated costs, and accompanying travel costs and productivity losses, before and after withdrawing TNF-α inhibitors (TNFi) in JIA patients. [METHODS] This was a retrospective analysis of prospectively collected data from electronic medical records of paediatric JIA pat...
DMARD; TNFi; biologics; costs; juvenile idiopathic arthritis; treatment; withdrawal
1.721
205
Pharmacology; Rheumatology
Medicine
2,024
38,111,256
Evaluation of ChatGPT's Real-Life Implementation in Undergraduate Dental Education: Mixed Methods Study.
JMIR medical education
JMIR Med Educ
10
null
10.2196/51344
eng
2,024
1
31
2,024
1
31
[BACKGROUND] The recent artificial intelligence tool ChatGPT seems to offer a range of benefits in academic education while also raising concerns. Relevant literature encompasses issues of plagiarism and academic dishonesty, as well as pedagogy and educational affordances; yet, no real-life implementation of ChatGPT in...
AI pedagogy; ChatGPT; LLM; artificial Intelligence; dental education; dental students; dentistry; higher education; large language models; learning assignments; natural language processing; university
1.974
36
Education
Social Sciences
2,024
38,109,102
Maternal Vaccine Effectiveness Against Influenza-Associated Hospitalizations and Emergency Department Visits in Infants.
JAMA pediatrics
JAMA Pediatr
178
2
10.1001/jamapediatrics.2023.5639
eng
2,024
2
1
null
null
null
[IMPORTANCE] Influenza virus infection during pregnancy is associated with severe maternal disease and may be associated with adverse birth outcomes. Inactivated influenza vaccine during pregnancy is safe and effective and can protect young infants, but recent evidence, particularly after the 2009 novel influenza A (H1...
null
5.085
231
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,106,143
The Impact of Low Protein Diet on the Molecular and Cellular Development of the Fetal Kidney.
bioRxiv : the preprint server for biology
bioRxiv
null
null
10.1101/2023.12.04.569988
eng
2,024
8
19
2,024
8
19
[BACKGROUND] Low nephron number has a direct impact on the development of hypertension and chronic kidney disease later in life. While intrauterine growth restriction caused by maternal low protein diet (LPD) is thought to be a significant cause of reduced nephron endowment in impoverished communities, its influence on...
null
null
null
null
null
null
38,105,679
Trends in Severe Obesity Among Children Aged 2 to 4 Years in WIC: 2010 to 2020.
Pediatrics
Pediatrics
153
1
10.1542/peds.2023-062461
eng
2,024
1
1
null
null
null
[OBJECTIVES] To examine the prevalence and trends in severe obesity among 16.6 million children aged 2 to 4 years enrolled in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) from 2010 to 2020. [METHODS] Severe obesity was defined as a sex-specific BMI for age ≥120% of the 95th percenti...
null
2.406
409
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,192,139
Curcumin- β-Cyclodextrin Molecular Inclusion Complex: A Water-Soluble Complex in Fast-dissolving Tablets for the Treatment ofNeurodegenerative Disorders.
Pharmaceutical nanotechnology
Pharm Nanotechnol
12
4
10.2174/0122117385273171231120051021
eng
2,024
null
null
null
null
null
[BACKGROUND] Orally disintegrating tablets (ODTs) have become an excellent choice for delivering drugs as their palatability is greatly improved. In this work, β-cyclodextrin has been used to improve the solubility of curcumin by encapsulating it into the hydrophobic cavity for the treatment of neurodegenerative disord...
Neusilin ULF2; curcumin; fast-dissolving oral tablets; sodium starch glycolate; solubility.
null
null
null
null
null
38,191,477
Identifying employee, workplace and population characteristics associated with COVID-19 outbreaks in the workplace: a population-based study.
Occupational and environmental medicine
Occup Environ Med
81
2
10.1136/oemed-2023-109032
eng
2,024
2
2
2,024
2
2
[OBJECTIVES] To identify risk factors that contribute to outbreaks of COVID-19 in the workplace and quantify their effect on outbreak risk. [METHODS] We identified outbreaks of COVID-19 cases in the workplace and investigated the characteristics of the individuals, the workplaces, the areas they work and the mode of co...
COVID-19; Disease Outbreaks; Epidemiology; Public health; Statistics
1.338
167
Public Health, Environmental and Occupational Health
Medicine
2,024
38,191,468
Evidence-practice gap analysis in the role of tick in brucellosis transmission: a scoping review.
Infectious diseases of poverty
Infect Dis Poverty
13
1
10.1186/s40249-023-01170-4
eng
2,024
1
8
2,024
1
8
[BACKGROUND] Brucellosis is a zoonotic affliction instigated by bacteria belonging to the genus Brucella and is characterized by a diverse range of pervasiveness, multiple transmission routes, and serious hazards. It is imperative to amalgamate the current knowledge and identify gaps pertaining to the role of ticks in ...
Brucella; Detection; Human infection; Risk evaluation; Tick
1.592
67
Infectious Diseases; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
38,191,446
Predictors of hospital nursing staff's adherence to safe injection guidelines: application of the protection motivation theory in Fars province, Iran.
BMC nursing
BMC Nurs
23
1
10.1186/s12912-023-01687-x
eng
2,024
1
9
2,024
1
9
[BACKGROUND] Needle stick injuries (NSI) can lead to dangerous infectious diseases for health care workers. This study aimed to determine the predictors of observance of safe injection guidelines in hospital nursing staff, based on protection motivation theory. [METHODS] This cross-sectional study was conducted on the ...
Guideline Adherence; Motivation; Needle-Stick Injuries; Nursing staff
1.272
62
Nursing
Nursing
2,024
38,191,421
Early warning systems for malaria outbreaks in Thailand: an anomaly detection approach.
Malaria journal
Malar J
23
1
10.1186/s12936-024-04837-x
eng
2,024
1
8
2,024
1
8
[BACKGROUND] Malaria continues to pose a significant health threat. Rapid identification of malaria infections and the deployment of active surveillance tools are crucial for achieving malaria elimination in regions where malaria is endemic, such as certain areas of Thailand. In this study, an anomaly detection system ...
Anomaly detection; Early detection; Malaria; Outbreak
1.143
126
Infectious Diseases; Parasitology
Immunology and Microbiology; Medicine
2,024
38,191,396
The residency levels' effect on pediatric dental rehabilitation operation time.
BMC medical education
BMC Med Educ
24
1
10.1186/s12909-023-05009-2
eng
2,024
1
8
2,024
1
8
[BACKGROUND] Postgraduate pediatric dental residents' competency, to perform dental rehabilitation procedures under General anesthesia (GA), at different levels of training is challenging for operation time control. An adequate operation time (OT) for children decreases morbidity risk and improves hospital time utiliza...
Dental procedure; General anesthesia; Operation time; Pediatric dental rehabilitation; Pediatric dental resident; Senior vs. junior
0.947
107
Education; Medicine
Medicine; Social Sciences
2,024
38,191,357
Risk factor analysis and risk prediction study of obesity in steelworkers: model development based on an occupational health examination cohort dataset.
Lipids in health and disease
Lipids Health Dis
23
1
10.1186/s12944-023-01994-x
eng
2,024
1
8
2,024
1
8
[BACKGROUND] Obesity is increasingly recognized as a grave public health concern globally. It is associated with prevalent diseases including coronary heart disease, fatty liver, type 2 diabetes, and dyslipidemia. Prior research has identified demographic, socioeconomic, lifestyle, and genetic factors as contributors t...
Obesity; Random forest; Risk factor analysis; Risk prediction; Steelworkers
1.24
105
Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,191,330
Establishment of a prognostic risk prediction model incorporating disulfidptosis-related lncRNA for patients with prostate cancer.
BMC cancer
BMC Cancer
24
1
10.1186/s12885-023-11778-2
eng
2,024
1
8
2,024
1
8
[PURPOSE] Prostate cancer (PCa) is one of the major tumor diseases that threaten men's health globally, and biochemical recurrence significantly impacts its prognosis. Disulfidptosis, a recently discovered cell death mechanism triggered by intracellular disulfide accumulation leading to membrane rupture, is a new area ...
AC026401.3; Biochemical recurrence-free survival; Disulfidptosis; Prostate cancer; lncRNA
1.178
171
Cancer Research; Genetics; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,191,305
Thyroid abscess associated with thyrotoxicosis caused by Yersinia enterocolitica subsp. palearctica in a patient with follicular adenoma of the thyroid gland.
BMC infectious diseases
BMC Infect Dis
24
1
10.1186/s12879-024-08974-1
eng
2,024
1
8
2,024
1
8
[BACKGROUND] Yersinia enterocolitica is a gram-negative zoonotic bacterial pathogen that is typically transmitted via the fecal-oral route. The most common clinical manifestation of a Y. enterocolitica infection is self-limited gastroenteritis. Although various extraintestinal manifestations of Y. enterocolitica infect...
Bacteremia; Thyroid abscess; Yersinia enterocolitica
1.035
137
Infectious Diseases
Medicine
2,024
38,190,888
Maternal Deaths Using Coroner's Data: A Latent Class Analysis.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
J Obstet Gynaecol Can
46
4
10.1016/j.jogc.2024.102349
eng
2,024
4
null
2,024
1
6
[OBJECTIVE] Knowledge regarding the antecedent clinical and social factors associated with maternal death around the time of pregnancy is limited. This study identified distinct subgroups of maternal deaths using population-based coroner's data, and that may inform ongoing preventative initiatives. [METHODS] A detailed...
cause of death; coroner; maternal mortality; overdose; pregnancy; suicide
0.575
86
Obstetrics and Gynecology
Medicine
2,024
38,190,883
Barriers to Office Hysteroscopy in Fellowship Education and Practice.
Journal of minimally invasive gynecology
J Minim Invasive Gynecol
31
4
10.1016/j.jmig.2024.01.003
eng
2,024
4
null
2,024
1
6
[STUDY OBJECTIVE] To identify the top 3 perceived barriers to performing office hysteroscopy (OH) by minimally invasive gynecologic surgery (MIGS) faculty and fellows and identify opportunities for education on this key topic that will be most effective in fellowship training and MIGS practice. [DESIGN] Cross-sectional...
Educational barriers; Fellowship education; Office hysteroscopy
0.829
97
Obstetrics and Gynecology
Medicine
2,024
38,190,341
Association Between Cannabis Use and Opioid Consumption, Pain, and Respiratory Complications After Surgery: A Retrospective Cohort Analysis.
Anesthesia and analgesia
Anesth Analg
139
4
10.1213/ANE.0000000000006785
eng
2,024
10
1
2,024
1
8
[BACKGROUND] Cannabis is a widely used illicit drug with effects on different pain pathways. However, interactions between cannabis and postoperative pain are unclear. Cannabis smoking also affects the lungs, but the impact of cannabis use on postoperative pulmonary complications is unknown. We hypothesized that preope...
null
1.161
237
Anesthesiology and Pain Medicine
Medicine
2,024
38,190,119
Central Body Fat Distribution and Kidney Function after Living Kidney Donation.
Clinical journal of the American Society of Nephrology : CJASN
Clin J Am Soc Nephrol
19
4
10.2215/CJN.0000000000000403
eng
2,024
4
1
2,024
1
8
[BACKGROUND] In most screening guidelines, high body mass index (BMI) is considered a contraindication for kidney donation. New insights suggest that central body fat distribution might provide greater power in assessing kidney risk. This study aimed to determine whether BMI and central body fat distribution measures a...
null
2.377
197
Critical Care and Intensive Care Medicine; Epidemiology; Nephrology; Transplantation
Medicine
2,024
38,190,074
Deep Learning Algorithm Trained on Oblique Cervical Radiographs to Predict Outcomes of Transforaminal Epidural Steroid Injection for Pain from Cervical Foraminal Stenosis.
Pain and therapy
Pain Ther
13
1
10.1007/s40122-023-00573-3
eng
2,024
2
null
2,024
1
8
[INTRODUCTION] We developed a convolutional neural network (CNN) model to predict treatment outcomes of transforaminal epidural steroid injection (TFESI) for controlling cervical radicular pain due to cervical foraminal stenosis. [METHODS] We retrospectively recruited 293 patients with cervical TFESI due to cervical ra...
Cervical spine; Convolutional neural network; Deep learning; Foraminal stenosis; Outcome; Prediction; Transforaminal epidural steroid injection
1.034
41
Anesthesiology and Pain Medicine; Neurology
Medicine
2,024
38,190,036
Pulmonary artery sarcoma and severe valvular diseases in late-septuagenarian women: was 2-stage surgery an appropriate strategy? A case report.
Surgical case reports
Surg Case Rep
10
1
10.1186/s40792-023-01805-6
eng
2,024
1
8
2,024
1
8
[BACKGROUND] Pulmonary artery sarcomas (PASs) are rare, and complete tumor resection is often difficult at the time of detection. We encountered a case of PAS that was thought to be resectable; however, the patient had severe symptomatic valvular disease. We faced a difficult decision regarding the surgical strategy. [...
Pulmonary artery sarcoma; Surgical approach; Surgical strategy; Two-stage surgery; Valvular disease
null
null
null
null
null
38,189,852
Correlation Between Insulin Resistance and Urinary Incontinence in Female Patients with Type 2 Diabetes Mellitus.
International urogynecology journal
Int Urogynecol J
35
2
10.1007/s00192-023-05715-x
eng
2,024
2
null
2,024
1
8
[INTRODUCTION AND HYPOTHESIS] Patients with type 2 diabetes mellitus (T2DM) are at a high risk of developing urinary incontinence; however, its pathogenesis is unclear. The purpose of this study is to explore the relationship between insulin resistance and urinary incontinence and its severity in female patients with T...
ICIQ-SF; Insulin resistance; Type 2 diabetes mellitus; Urinary incontinence
0.778
109
Obstetrics and Gynecology; Urology
Medicine
2,024
38,189,724
Work-related stress is associated with low work ability, but not with poor self-rated health: A cross-sectional study in primary healthcare.
Work (Reading, Mass.)
Work
78
4
10.3233/WOR-230141
eng
2,024
null
null
null
null
null
[BACKGROUND] People seeking care at primary healthcare centres may be exposed to work-related stress, increasing the risk of future sick leave. Thus, it is important to identify work-related stress, and to explore how stress relates to work ability and health. [OBJECTIVE] To investigate the association between work-rel...
Occupational health; mental health; occupational stress; primary care; primary prevention; work performance
null
null
null
null
null
38,189,533
Beyond the Gut: A Systematic Review and Meta-analysis of Advanced Therapies for Inflammatory Bowel Disease-associated Extraintestinal Manifestations.
Journal of Crohn's & colitis
J Crohns Colitis
18
6
10.1093/ecco-jcc/jjae002
eng
2,024
6
3
null
null
null
[BACKGROUND AND AIMS] Extraintestinal manifestations are frequent in patients with inflammatory bowel disease and have a negative impact on quality of life. Currently, however, there is no evidence available to determine which drug should be recommended for these patients beyond anti-tumour necrosis factor [anti-TNF] t...
Extraintestinal manifestations; biological products; inflammatory bowel disease
null
null
null
null
null
38,189,106
Making oral comprehension interventions TIDieR: A narrative synthesis of interventions improving comprehension in children from 1 to 5 years with language difficulties.
International journal of language & communication disorders
Int J Lang Commun Disord
59
4
10.1111/1460-6984.12998
eng
2,024
null
null
2,024
1
8
[BACKGROUND] Oral comprehension difficulties are prevalent in preschool children with language difficulties and are frequently the target of speech and language therapy (SLT) intervention. To support the implementation of research to practice, there is a need to identify effective interventions for this population and ...
TIDieR; comprehension; intervention; language difficulties; preschool
null
null
null
null
null
38,186,562
High-Throughput Computing to Automate Population-Based Studies to Detect the 30-Day Risk of Adverse Outcomes After New Outpatient Medication Use in Older Adults with Chronic Kidney Disease: A Clinical Research Protocol.
Canadian journal of kidney health and disease
Can J Kidney Health Dis
11
null
10.1177/20543581231221891
eng
2,024
null
null
2,024
1
6
[BACKGROUND] Safety issues are detected in about one third of prescription drugs in the years following regulatory agency approval. Older adults, especially those with chronic kidney disease, are at particular risk of adverse reactions to prescription drugs. This protocol describes a new approach that may identify cred...
adverse drug events; automation; chronic kidney disease; drug; drug safety; high-throughput computing; machine learning; medication; pharmaco-epidemiology; pharmaco-informatics; pharmacovigilance; postmarket drug surveillance; real-world data
0.651
37
Nephrology
Medicine
2,024
38,186,292
Corrected Age at Bayley Assessment and Developmental Delay in Extreme Preterms.
Pediatrics
Pediatrics
153
2
10.1542/peds.2023-063654
eng
2,024
1
1
null
null
null
[BACKGROUND AND OBJECTIVES] Research on outcomes of prematurity frequently examines neurodevelopment in the toddler years as an end point, but the age range at examination varies. We aimed to evaluate whether the corrected age (CA) at Bayley-III assessment is associated with rates of developmental delay in extremely pr...
null
2.406
409
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,185,988
The impact of prediabetes and diabetes on endothelial function in a large population-based cohort.
Blood pressure
Blood Press
33
1
10.1080/08037051.2023.2298309
eng
2,024
12
null
2,024
1
7
[BACKGROUND] Diabetes and prediabetes are well-recognized risk factors for cardiovascular disease (CVD) and are marked by vascular endothelial dysfunction (ED). However, there is a scarcity of thorough population-based studies examining ED in individuals with diabetes/prediabetes free from manifest CVD. Here, we examin...
Cardiovascular disease; Diabetes; Endothelial dysfunction; Prediabetes; Reactive hyperaemia index
0.551
58
Cardiology and Cardiovascular Medicine; Internal Medicine; Medicine
Medicine
2,024
38,185,460
Optimal Frequency in Repetitive Transcranial Magnetic Stimulation for the Management of Chronic Pain: A Network Meta-Analysis of Randomized Controlled Trials.
World neurosurgery
World Neurosurg
184
null
10.1016/j.wneu.2024.01.010
eng
2,024
4
null
2,024
1
6
[OBJECTIVE] Repetitive Transcranial Magnetic Stimulation (rTMS) has been shown to be effective for pain modulation in a variety of pathological conditions causing neuropathic pain. The purpose of this study is to conduct a network meta-analysis (NMA) of randomized control trials to identify the most optimal frequency r...
Network meta-analysis; Optimal frequency; Pain; rTMS
0.709
123
Neurology; Surgery
Medicine
2,024
38,184,602
Early left ventricular microvascular dysfunction in diabetic pigs: a longitudinal quantitative myocardial perfusion CMR study.
Cardiovascular diabetology
Cardiovasc Diabetol
23
1
10.1186/s12933-023-02106-w
eng
2,024
1
6
2,024
1
6
[BACKGROUND] Microvascular pathology is one of the main characteristics of diabetic cardiomyopathy; however, the early longitudinal course of diabetic microvascular dysfunction remains uncertain. This study aimed to investigate the early dynamic changes in left ventricular (LV) microvascular function in diabetic pig mo...
Diabetes; Microvascular dysfunction; Myocardial microvascular reserve function.; Quantitative myocardial perfusion
3.353
121
Cardiology and Cardiovascular Medicine; Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,024
38,184,489
Pharmacokinetics, Pharmacodynamics, and Safety of Single Dose HSK7653 Tablets in Chinese Subjects with Normal or Impaired Renal Function.
Clinical pharmacokinetics
Clin Pharmacokinet
63
2
10.1007/s40262-023-01333-4
eng
2,024
2
null
2,024
1
6
[OBJECTIVE] HSK7653 is a novel, ultralong-acting dipeptidyl peptidase-4 (DPP-4) inhibitor, promising for type 2 diabetes mellitus with a dosing regimen of once every 2 weeks. This trial investigates the pharmacokinetics (PKs), pharmacodynamics (PDs),and safety of HSK7653 in outpatients with normal or impaired renal fun...
null
1.305
191
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,183,964
Time-driven activity-based costing (TDABC) of direct-to-angiography pathway for acute ischemic stroke patients with suspected large vessel occlusion.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
33
3
10.1016/j.jstrokecerebrovasdis.2023.107516
eng
2,024
3
null
2,024
1
6
[INTRODUCTION] Direct-to-angiography (DTA) is a novel care pathway for endovascular treatment (EVT) of acute ischemic stroke (AIS) that has been shown to reduce time-to-treatment and improve clinical outcomes for EVT-eligible patients. The institutional costs of adopting the DTA pathway and the many factors affecting c...
Care pathways; Costs; DTA; Stroke; TDABC
0.688
85
Rehabilitation; Cardiology and Cardiovascular Medicine; Neurology; Surgery
Medicine
2,024
38,183,462
Comparison of substernal and posterior mediastinal route of reconstruction after minimally invasive esophagectomy for esophageal cancer.
Langenbeck's archives of surgery
Langenbecks Arch Surg
409
1
10.1007/s00423-023-03215-6
eng
2,024
1
6
2,024
1
6
[BACKGROUND] Substernal (ST) and posterior mediastinal (PM) routes are the two most common for reconstruction after esophagectomy with cervical anastomosis. Recent evidence showed similar outcomes between the routes; thus, the superior choice remained controversial. This study aimed to compare the short-term outcomes o...
Esophageal cancer; McKeown minimally invasive esophagectomy; Posterior mediastinal route; Substernal route
0.694
94
Surgery
Medicine
2,024
38,183,433
Programmed cell death 4 governs NLRP3-mediated pyroptosis in septic lung disorders.
Molecular biology reports
Mol Biol Rep
51
1
10.1007/s11033-023-08948-7
eng
2,024
1
6
2,024
1
6
[INTRODUCTION] Sepsis is a pathogenic syndrome of prolonged excessive inflammation and immunosuppression produced by invading pathogens. Programmed cell death 4 (PDCD4) may be implicated in a range of inflammatory lesions, and this study aimed to confirm the involvement of PDCD4 in septic lung injury. [MATERIALS AND ME...
NLRP3; PDCD4; Pyroptosis; Septic lung injury
0.71
96
Genetics; Medicine; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,183,165
Prevalence of acute periapical abscesses in head and neck cancer patients receiving radiotherapy.
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
Spec Care Dentist
44
3
10.1111/scd.12952
eng
2,024
null
null
2,024
1
5
[AIMS] Head and neck cancer is a serious condition affecting the life of patients. Radiotherapy is commonly used to treat such conditions. The aim of this study was to assess the prevalence of acute periapical abscesses (PAs) in patients who received radiotherapy for head and neck cancer. [METHODS AND RESULTS] Data on ...
Abscess; Cancer; Dental Abscess; Head & Neck Cancer; Oropharynx; Periapical Abscess; Radiotherapy
0.39
51
Dentistry
Dentistry
2,024
38,182,656
Mid-term real world outcomes of the Hydrus[®] Microstent in open angle glaucoma.
Eye (London, England)
Eye (Lond)
38
8
10.1038/s41433-023-02920-2
eng
2,024
6
null
2,024
1
5
[PURPOSE] To evaluate the mid-term clinical results and the safety aspects of the Hydrus[®] Microstent (Ivantis, Inc, Irvine, CA) in a real-life setting. [DESIGN] Retrospective case series. [METHODS] Hydrus[®] Microstent was implanted in phakic eyes (88 eyes, 87.1%) and in pseudophakic eyes (13 eyes, 12.9%), respective...
null
null
null
null
null
null
38,182,128
Chronic neutropenia in childhood: experience of a tertiary center.
Jornal de pediatria
J Pediatr (Rio J)
100
3
10.1016/j.jped.2023.12.003
eng
2,024
null
null
2,024
1
2
[OBJECTIVE] To assess the prevalence of chronic neutropenia (CN) and the clinical profile of patients with CN aged up to 18 years, followed in the pediatric hematology, rheumatology, or immunology outpatient clinic of a tertiary medical center from May 1, 2018, to 30 April 2019. [METHODS] Retrospective observational st...
Autoimmune neutropenia; Childhood; Chronic neutropenia; Idiopathic neutropenia
0.707
66
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,181,396
Differences in Pain Experience Among Different Racial and Ethnic Groups.
Physical therapy
Phys Ther
104
10
10.1093/ptj/pzae001
eng
2,024
10
2
null
null
null
[OBJECTIVE] The objective of this study was to examine the role of pain catastrophizing and pain self-efficacy as possible mediators of race-based differences in pain intensity and to evaluate the possible moderating role of race on the relationship between pain catastrophizing and pain self-efficacy with pain outcomes...
Catastrophizing; Intensity; Pain; Race; Self-Efficacy
1.233
184
Physical Therapy, Sports Therapy and Rehabilitation
Health Professions
2,024
38,181,055
Phase II Study of the Liposomal Formulation of Eribulin (E7389-LF) in Combination with Nivolumab: Results from the Small Cell Lung Cancer Cohort.
Cancer research communications
Cancer Res Commun
4
1
10.1158/2767-9764.CRC-23-0313
eng
2,024
1
29
null
null
null
[PURPOSE] E7389-LF is a liposomal formulation of eribulin that contributes to tumor vascular remodeling. The phase II part of this phase Ib/II study assessed the efficacy/safety of E7389-LF in combination with nivolumab in several disease cohorts; herein, we report results from the small cell lung cancer (SCLC) cohort....
null
1.569
15
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,180,796
Dissemination Strategies for mHealth Apps: Systematic Review.
JMIR mHealth and uHealth
JMIR Mhealth Uhealth
12
null
10.2196/50293
eng
2,024
1
5
2,024
1
5
[BACKGROUND] Among the millions of mobile apps in existence, thousands fall under the category of mobile health (mHealth). Although the utility of mHealth apps has been demonstrated for disease diagnosis, treatment data management, and health promotion strategies, to be effective they must reach and be used by their ta...
adoption; app; apps; consumer; digital marketing; dissemination; engagement; mHealth; mHealth apps; market; marketing; marketing strategies; mobile health; mobile health apps; mobile phone; onboarding; systematic; systematic review
1.787
107
Health Informatics
Medicine
2,024
38,180,756
Xylazine in Overdose Deaths and Forensic Drug Reports in US States, 2019-2022.
JAMA network open
JAMA Netw Open
7
1
10.1001/jamanetworkopen.2023.50630
eng
2,024
1
2
2,024
1
2
[IMPORTANCE] Xylazine is increasingly reported in street drugs and fatal overdoses in the US, yet state-level data are limited, hampering local public health responses. [OBJECTIVE] To gather available state-level data on xylazine involvement in overdose deaths and in forensic drug reports. [DESIGN, SETTING, AND PARTICI...
null
3.546
154
Medicine
Medicine
2,024
38,180,537
Factorial structure of the Internet Gaming Disorder questionnaire in the Italian setting: a single-factored ailment or a multifaceted condition?
European child adolescent psychiatry
Eur Child Adolesc Psychiatry
33
8
10.1007/s00787-023-02322-5
eng
2,024
8
null
2,024
1
5
[INTRODUCTION] Internet Gaming Disorder (IGD) according to DSM-5 is a behavioral addiction needing additional study. IGD in youth is correlated with anxiety, depression, attention problems, interpersonal problems, social phobia, behavior problems and low academic achievement. The aim of the present research is to contr...
Addiction; Anxiety; Depression; Internet Gaming Disorder; Videogames
null
null
null
null
null
38,179,726
Prevalence and risk factors of non-tuberculous mycobacterial pulmonary isolates and infection in interstitial lung disease associated with systemic autoimmune disease.
Clinical and experimental rheumatology
Clin Exp Rheumatol
42
5
10.55563/clinexprheumatol/c4oq1k
eng
2,024
5
null
2,024
1
3
[OBJECTIVES] Non-tuberculous mycobacterial (NTM) lung disease (NTM-LD) prevalence is increasing worldwide. In this study, we aimed to evaluate the clinical significance of NTM pulmonary isolates (NTM-PI) and NTM-LD in patients with systemic autoimmune disease (SAD) who had a concurrent interstitial lung disease (ILD) d...
null
1.004
112
Immunology; Immunology and Allergy; Rheumatology
Immunology and Microbiology; Medicine
2,024
38,179,583
Physically Active Adults with Low Back Pain do not Demonstrate Altered Deadlift Mechanics: A Novel Application of Myotonometry to Estimate Inter-Muscular Load Sharing.
International journal of sports physical therapy
Int J Sports Phys Ther
19
1
10.26603/001c.90707
eng
2,024
null
null
2,024
1
2
[BACKGROUND] Rehabilitation clinicians that work with physically active populations are challenged with how to safely return patients back to performing deadlift movements following low back injury. Application of reliable and valid tests and measures to quantify impairments related to low back pain (LBP) enhances clin...
Muscle stiffness; clinical decision making; neuromuscular function; rehabilitation
0.77
22
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Orthopedics and Sports Medicine
Health Professions; Medicine
2,024
38,178,555
The role of nursing care continuity report in predicting length of hospital stay in older people: A retrospective cohort study.
Journal of clinical nursing
J Clin Nurs
33
5
10.1111/jocn.16953
eng
2,024
5
null
2,024
1
4
[BACKGROUND] The Nursing Care Continuity Report (NCCR) is a tool for evaluating the quality of nursing care during hospital admission. [AIM] To explore the role of the NCCR in predicting longer length of stay (LOS) in older adults (≥65 years) admitted to a tertiary hospital and determine possible clinical differences a...
Barthel index; Norton scale; Nursing Care Continuity Report; hospitalisation; pain; pressure ulcer
1.322
131
Medicine; Nursing
Medicine; Nursing
2,024
38,178,261
Selective regulation of endophytic bacteria and gene expression in soybean by water-soluble humic materials.
Environmental microbiome
Environ Microbiome
19
1
10.1186/s40793-023-00546-1
eng
2,024
1
4
2,024
1
4
[BACKGROUND] As part of the plant microbiome, endophytic bacteria play an essential role in plant growth and resistance to stress. Water-soluble humic materials (WSHM) is widely used in sustainable agriculture as a natural and non-polluting plant growth regulator to promote the growth of plants and beneficial bacteria....
Community assembly; Endophyte; Ethylene; Sphingobium; Transcriptomic; Water-soluble humic materials
null
null
null
null
null
38,178,210
PiRNA hsa_piR_019949 promotes chondrocyte anabolic metabolism by inhibiting the expression of lncRNA NEAT1.
Journal of orthopaedic surgery and research
J Orthop Surg Res
19
1
10.1186/s13018-023-04511-z
eng
2,024
1
4
2,024
1
4
[BACKGROUND] Osteoarthritis is a prevalent degenerative joint condition typically found in individuals who are aged 50 years or older. In this study, the focus is on PIWI-interacting RNA (piRNA), which belongs to a category of small non-coding RNAs. These piRNAs play a role in the regulation of gene expression and the ...
Chondrocyte; NEAT1; NLRP3; Osteoarthritis; piRNA
0.877
75
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
38,177,609
Designing viable, durable physical activity programs for cancer survivors: reflections from program participants and organizational leaders.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
32
1
10.1007/s00520-023-08264-7
eng
2,024
1
5
2,024
1
5
[PURPOSE] Despite recommendations for cancer survivors to participate in routine physical activity (PA), offering programs that fit both survivors' needs and sponsoring organizations' resources remains a challenge. The purpose of this study is to explore the perspectives of cancer survivors and organizational stakehold...
Cancer; Organizational stakeholders; Physical activity; Qualitative research; Survivorship
1.109
143
Oncology; Rehabilitation; Oncology
Medicine; Nursing
2,024
38,176,897
ATP citrate lyase (ACLY)-dependent immunometabolism in mucosal T cells drives experimental colitis in vivo.
Gut
Gut
73
4
10.1136/gutjnl-2023-330543
eng
2,024
3
7
2,024
3
7
[OBJECTIVE] Mucosal T cells play a major role in inflammatory bowel disease (IBD). However, their immunometabolism during intestinal inflammation is poorly understood. Due to its impact on cellular metabolism and proinflammatory immune cell function, we here focus on the enzyme ATP citrate lyase (ACLY) in mucosal T cel...
EXPERIMENTAL COLITIS; INFLAMMATORY BOWEL DISEASE; MUCOSAL IMMUNOLOGY; T LYMPHOCYTES
8.874
364
Gastroenterology
Medicine
2,024
38,175,140
Capturing the holistic value of biosimilars in Europe - part 1: a historical perspective.
Expert review of pharmacoeconomics outcomes research
Expert Rev Pharmacoecon Outcomes Res
24
2
10.1080/14737167.2023.2297926
eng
2,024
2
null
2,024
1
25
[INTRODUCTION] Approved biosimilars exhibit comparable efficacy, safety, and immunogenicity to reference products. This report provides perspectives on the societal value of biosimilars within Europe and potential factors that have influenced market dynamics. [METHODS] An independent, self-administered survey or one-on...
Biosimilar; Europe; drug benefits; medicines policy; quality of care; reimbursement
null
null
null
null
null
38,174,786
Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials: a meta-epidemiological study.
The Cochrane database of systematic reviews
Cochrane Database Syst Rev
1
1
10.1002/14651858.MR000034.pub3
eng
2,024
1
4
2,024
1
4
[BACKGROUND] Researchers and decision-makers often use evidence from randomised controlled trials (RCTs) to determine the efficacy or effectiveness of a treatment or intervention. Studies with observational designs are often used to measure the effectiveness of an intervention in 'real world' scenarios. Numerous study ...
null
1.623
341
Medicine; Pharmacology
Medicine
2,024
38,174,571
Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study.
Stroke
Stroke
55
2
10.1161/STROKEAHA.123.043777
eng
2,024
2
null
2,024
1
4
[BACKGROUND] The effectiveness of intravenous thrombolysis (IVT) before endovascular treatment (EVT) has been investigated in randomized trials and meta-analyses. These studies mainly concerned anterior circulation occlusions. We aimed to investigate clinical, technical, and safety outcomes of IVT before EVT in posteri...
posterior circulation; stroke; thrombectomy; thrombolytic therapy
2.659
370
Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience
Medicine; Neuroscience; Nursing
2,024
38,173,041
Association of health behaviors with function and health-related quality of life among patients with Parkinson's disease.
Israel journal of health policy research
Isr J Health Policy Res
13
1
10.1186/s13584-023-00588-3
eng
2,024
1
3
2,024
1
3
[BACKGROUND] Current evidence on chronic conditions favors promotion of health behaviors as a mean to positively impact health outcomes. In Parkinson's disease, performing health behaviors is indicated as a means to fight the long-lasting burden of the disease. Understanding actual engagement in health behaviors and pa...
Health behaviors; Health related quality of life; Patient activation; Structural equation modeling
0.632
33
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,024
38,173,020
Building a resilient health system for universal health coverage and health security: a systematic review.
Global health research and policy
Glob Health Res Policy
9
1
10.1186/s41256-023-00340-z
eng
2,024
1
4
2,024
1
4
[BACKGROUND] Resilient health system (RHS) is crucial to achieving universal health coverage (UHC) and health security. However, little is known about strategies towards RHS to improve UHC and health security. This systematic review aims to synthesise the literature to understand approaches to build RHS toward UHC and ...
Health security; Health system; Resilient; Universal health coverage
1.242
36
Epidemiology; Health Policy; Health; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,024
38,172,991
Virus-like particle-mediated delivery of structure-selected neoantigens demonstrates immunogenicity and antitumoral activity in mice.
Journal of translational medicine
J Transl Med
22
1
10.1186/s12967-023-04843-8
eng
2,024
1
3
2,024
1
3
[BACKGROUND] Neoantigens are patient- and tumor-specific peptides that arise from somatic mutations. They stand as promising targets for personalized therapeutic cancer vaccines. The identification process for neoantigens has evolved with the use of next-generation sequencing technologies and bioinformatic tools in tum...
Cancer vaccine; Immunotherapy; Neoantigen; T cell response; Virus-like particle
1.997
153
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,172,965
Altered neurophysiological responses during empathy for pain in insomnia: evidence from an EEG study in non-clinical samples.
Journal of physiological anthropology
J Physiol Anthropol
43
1
10.1186/s40101-023-00351-2
eng
2,024
1
3
2,024
1
3
[BACKGROUND] This study aims to investigate the behavioral and neurophysiological changes accompanying the empathy for pain among individuals with insomnia in nonclinical samples, which has been scarcely explored in the existing literature despite the deleterious effects of sleep disturbance on social behavior, and int...
Empathy for pain; Event-related potentials; Insomnia; Time-frequency analysis
0.668
63
Anthropology; Human Factors and Ergonomics; Orthopedics and Sports Medicine; Public Health, Environmental and Occupational Health; Physiology; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine; Social Sciences
2,024
38,172,899
Pain management in German hospices: a cross-sectional study.
BMC palliative care
BMC Palliat Care
23
1
10.1186/s12904-023-01291-5
eng
2,024
1
3
2,024
1
3
[BACKGROUND AND OBJECTIVES] Pain management is a necessary component of palliative care as most patients suffer from pain during the final phase of life. Due to the complex causation of pain in the last phase of life, it is important to utilize methods other than pharmacotherapeutic options in order to achieve adequate...
Hospice; Pain management; Pain medication; Palliative care; Palliative sedation
1.046
62
Medicine
Medicine
2,024
38,172,828
The association between hyperuricemia and insulin resistance surrogates, dietary- and lifestyle insulin resistance indices in an Iranian population: MASHAD cohort study.
Nutrition journal
Nutr J
23
1
10.1186/s12937-023-00904-2
eng
2,024
1
4
2,024
1
4
[BACKGROUND] Previous studies have reported insulin resistance (IR) to be associated with hyperuricemia. In this study, we aimed to assess the possible associations between the empirical dietary index for IR (EDIR), the empirical lifestyle index for IR (ELIR), and non-insulin-based surrogates (triglyceride-glucose (TyG...
Empirical dietary index for insulin resistance; Empirical lifestyle index for insulin resistance; Hyperuricemia; Insulin resistance
1.221
119
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
38,172,743
Mechanisms by which silencing long-stranded noncoding RNA KCNQ1OT1 alleviates myocardial ischemia/reperfusion injury (MI/RI)-induced cardiac injury via miR-377-3p/HMOX1.
BMC cardiovascular disorders
BMC Cardiovasc Disord
24
1
10.1186/s12872-023-03693-y
eng
2,024
1
3
2,024
1
3
[BACKGROUND] The key complication of myocardial infarction therapy is myocardial ischemia/reperfusion injury (MI/RI), and there is no effective treatment. The present study elucidates the mechanism of action of lncRNA KCNQ1OT1 in alleviating MI/RI and provides new perspectives and therapeutic targets for cardiac injury...
HMOX1; Myocardial ischemia-reperfusion injury; Oxidative stress; lncRNA KCNQ1OT1; miR-377-3p
0.708
76
Cardiology and Cardiovascular Medicine
Medicine
2,024
38,171,619
Social and clinical vulnerability in stroke and STEMI management during the COVID-19 pandemic: a registry-based study.
BMJ open
BMJ Open
14
1
10.1136/bmjopen-2023-073933
eng
2,024
1
3
2,024
1
3
[OBJECTIVE] This study aims to evaluate whether the first wave of the COVID-19 pandemic resulted in a deterioration in the quality of care for socially and/or clinically vulnerable stroke and ST-segment elevation myocardial infarction (STEMI) patients. [DESIGN] Two cohorts of STEMI and stroke patients in the Aquitaine ...
COVID-19; Health Equity; Health Services Accessibility; Health policy; Organisation of health services; Quality in health care
1.016
176
Medicine
Medicine
2,024
38,171,499
Association Between Baseline Gait Parameters and Future Fall Risk in Patients With De Novo Parkinson's Disease: Forward Versus Backward Gait.
Journal of clinical neurology (Seoul, Korea)
J Clin Neurol
20
2
10.3988/jcn.2022.0299
eng
2,024
3
null
2,024
1
1
[BACKGROUND AND PURPOSE] Falls are not uncommon even in patients with early stages of Parkinson's disease (PD). The aims of this study were to determine the relationships between gait parameters and falls and identify crucial gait parameters for predicting future falls in patients with de novo PD. [METHODS] We prospect...
Parkinson's disease; backward gait; falls; forward gait; gait parameters
0.1
4
Neurology; Neurology
Medicine; Neuroscience
2,016
38,171,416
Improved Structure and Function in Early-Detected Second-Eye Neovascular Age-Related Macular Degeneration: FASBAT/Early Detection of Neovascular Age-Related Macular Degeneration Report 1.
Ophthalmology. Retina
Ophthalmol Retina
8
6
10.1016/j.oret.2023.12.012
eng
2,024
6
null
2,024
1
1
[PURPOSE] Visual acuity (VA) and structural biomarker assessment before and 24-months after early detection and routine treatment of second-eye involvement with neovascular age-related macular degeneration (nAMD) and additional comparison with the first eye affected. [DESIGN] Prospective, 22-center observational study ...
Early detection; Hyperreflective material; Intraretinal fluid; Neovascular age-related macular degeneration; Second eyes
1.982
53
Ophthalmology
Medicine
2,024
38,171,211
The Diagnostic Role of Repeated Biopsy of Thyroid Nodules with Atypia of Undetermined Significance with Architectural Atypia on Core-Needle Biopsy.
Endocrinology and metabolism (Seoul, Korea)
Endocrinol Metab (Seoul)
39
2
10.3803/EnM.2023.1818
eng
2,024
4
null
2,024
1
3
[BACKGRUOUND] We aimed to evaluate the utility of repeat biopsy of thyroid nodules classified as atypia of undetermined significance with architectural atypia (IIIB) on core-needle biopsy (CNB). [METHODS] This retrospective study evaluated patients with thyroid nodules categorized as IIIB on CNB between 2013 and 2015. ...
Core needle biopsy; Thyroid; Thyroid nodule; Ultrasonography
1.487
53
Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,170,669
Nasal Lining Repair: A Comprehensive Literature Review.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
Dermatol Surg
50
3
10.1097/DSS.0000000000004063
eng
2,024
3
1
2,024
1
3
[BACKGROUND] Currently, there are limited reviews in the dermatology literature on how to approach reconstruction of nasal lining in full-thickness nasal defects resulting from Mohs micrographic surgery. Given variable training and experience, dermatologic surgeons may seek additional references to help reconstruct cer...
null
0.558
146
Dermatology; Medicine; Surgery
Medicine
2,024
38,170,574
Early Detection of Molecular Residual Disease and Risk Stratification for Children with Acute Myeloid Leukemia via Circulating Tumor DNA.
Clinical cancer research : an official journal of the American Association for Cancer Research
Clin Cancer Res
30
6
10.1158/1078-0432.CCR-23-2589
eng
2,024
3
15
null
null
null
[PURPOSE] Patient-tailored minimal residual disease (MRD) monitoring based on circulating tumor DNA (ctDNA) sequencing of leukemia-specific mutations enables early detection of relapse for pre-emptive treatment, but its utilization in pediatric acute myelogenous leukemia (AML) is scarce. Thus, we aim to examine the rol...
null
4.8
392
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,170,546
Peripheral microvascular function is linked to cardiac involvement on cardiovascular magnetic resonance in systemic sclerosis-related pulmonary arterial hypertension.
European heart journal. Cardiovascular Imaging
Eur Heart J Cardiovasc Imaging
25
5
10.1093/ehjci/jeae001
eng
2,024
4
30
null
null
null
[AIMS] Systemic sclerosis (SSc) is characterized by vasculopathy, inflammation, and fibrosis, and carries one of the worst prognoses if patients also develop pulmonary arterial hypertension (PAH). Although PAH is a known prognosticator, patients with SSc-PAH demonstrate disproportionately high mortality, presumably due...
cardiac magnetic resonance imaging; nailfold capillaroscopy; parametric mapping; pulmonary arterial hypertension; systemic sclerosis
null
null
null
null
null
38,170,306
Comparison of neuroprotective effects of a topiramate-loaded biocomposite based on mesoporous silica nanoparticles with pure topiramate against methylphenidate-induced neurodegeneration.
Molecular biology reports
Mol Biol Rep
51
1
10.1007/s11033-023-09011-1
eng
2,024
1
3
2,024
1
3
[BACKGROUND] Methylphenidate (MPH) abuse has been criticized for its role in neurodegeneration. Also, a high risk of seizure was reported in the first month of MPH treatment. Topiramate, a broad-spectrum Antiepileptic Drug (AED), has been used as a neuroprotective agent in both aforementioned complications. Nanotechnol...
Apoptosis; Inflammation; Methylphenidate; Nanoparticles; Oxidative stress; Seizure; Topiramate
0.71
96
Genetics; Medicine; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,170,270
The efficacy of ultrasound-guided erector spinae plane block (ESPB) versus freehand ESPB in postoperative pain management after lumbar spinal fusion surgery: a randomized, non-inferiority trial.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Eur Spine J
33
3
10.1007/s00586-023-08101-9
eng
2,024
3
null
2,024
1
3
[PURPOSE] Spine surgeries have experienced exponential growth over the past 2 decades. These surgeries are often accompanied by long and severe perioperative pain, presenting a significant management challenge. This study aims to assess and compare the efficacy of two techniques for postoperative pain (POP) management ...
Freehand erector spinae plane block; Lumbar spinal fusion surgery; Postoperative pain; Ultrasound-guided erector spinae plane block
1.076
173
Orthopedics and Sports Medicine; Surgery
Medicine
2,024