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38,942,389
Utilizing the Ex-Vivo Bovine Model in Retrograde Intrarenal Surgery Training.
Urology
Urology
191
null
10.1016/j.urology.2024.06.053
eng
2,024
9
null
2,024
6
26
[OBJECTIVE] To present an ex-vivo bovine model for retrograde intrarenal surgery (RIRS) training. [MATERIALS AND METHODS] The model was specifically developed for a pre-congress course organized as part of the National Pediatric Urology Congress. The course involved a 2-day online theoretical segment followed by hands-...
null
0.756
197
Urology
Medicine
2,024
38,942,256
Urinary metabolite concentrations of phthalate and plasticizers in infancy and childhood in the UNC baby connectome project.
Environmental research
Environ Res
259
null
10.1016/j.envres.2024.119467
eng
2,024
10
15
2,024
6
27
[INTRODUCTION] Existing evidence suggests that exposure to phthalates is higher among younger age groups. However, limited knowledge exists on how phthalate exposure, as well as exposure to replacement plasticizers, di(isononyl) cyclohexane-1,2-dicarboxylate (DINCH) and di-2-ethylhexyl terephthalate (DEHTP), change fro...
Childhood; Infancy; Metabolism; Phthalates; Replacement plasticizers
1.822
196
Biochemistry; Environmental Science; Public Health, Environmental and Occupational Health
Biochemistry, Genetics and Molecular Biology; Environmental Science; Medicine
2,024
38,942,194
Exploring the role of DNMT1 in dental papilla cell fate specification during mouse tooth germ development through integrated single-cell transcriptomics and bulk RNA sequencing.
Journal of oral biosciences
J Oral Biosci
66
3
10.1016/j.job.2024.06.010
eng
2,024
9
null
2,024
6
26
[OBJECTIVES] This study aimed to investigate the regulatory mechanisms governing dental mesenchymal cell commitment during tooth development, focusing on odontoblast differentiation and the role of epigenetic regulation in this process. [METHODS] We performed single-cell RNA sequencing (scRNA-seq) of dental cells from ...
Dental mesenchymal cells; Dental papilla; Dnmt1; Tooth development; scRNA-seq
0.601
29
Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine
Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine
2,024
38,942,181
Revisiting GDF9 variants in primary ovarian insufficiency: A shift from dominant to recessive pathogenicity?
Gene
Gene
927
null
10.1016/j.gene.2024.148734
eng
2,024
11
15
2,024
6
26
[BACKGROUND] Primary ovarian insufficiency (POI) affects around 2-4% of women before the age of 40. Genetic factors play an important role in POI. The GDF9 gene has been identified as a significant genetic contributor of POI. However, the pathogenicity and penetrance of GDF9 variants remain uncertain. [METHODS] A next-...
GDF9; Penetrance; Premature ovarian insufficiency
0.682
200
Medicine; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,942,117
Gestational weight gain below recommendations and adverse maternal and child health outcomes for pregnancies with overweight or obesity: a United States cohort study.
The American journal of clinical nutrition
Am J Clin Nutr
120
3
10.1016/j.ajcnut.2024.06.011
eng
2,024
9
null
2,024
6
26
[BACKGROUND] The current Institute of Medicine (IOM) pregnancy weight gain guidelines were developed using the best available evidence but were limited by substantial knowledge gaps. Some have raised concern that the guidelines for individuals affected by overweight or obesity are too high and contribute to short- and ...
cohort study; epidemiology; nutrition; obstetrics; perinatal; public health recommendations
2.111
390
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
38,941,860
Impact of geometric and hemodynamic changes on a mechanobiological model of atherosclerosis.
Computer methods and programs in biomedicine
Comput Methods Programs Biomed
254
null
10.1016/j.cmpb.2024.108296
eng
2,024
9
null
2,024
6
24
[BACKGROUND AND OBJECTIVE] In this work, the analysis of the importance of hemodynamic updates on a mechanobiological model of atheroma plaque formation is proposed. [METHODS] For that, we use an idealized and axisymmetric model of carotid artery. In addition, the behavior of endothelial cells depending on hemodynamica...
2D-axisymmetric model; Atherosclerosis; Carotid artery; Double stenosis phenomenon; Geometry and hemodynamic changes; Three pore model
1.13
150
Computer Science Applications; Health Informatics; Software
Computer Science; Medicine
2,024
38,941,649
The natural course, treatment outcomes, and long-term prognosis of cervical spinal cord arteriovenous shunts.
Journal of neurosurgery
J Neurosurg
141
5
10.3171/2024.4.JNS232552
eng
2,024
11
1
2,024
6
28
[OBJECTIVE] The highly intricate nature of the cervical spinal cord can cause arteriovenous shunts in these segments that may be associated with heightened clinical risks and treatment complexities. In this article, the authors aimed to provide a comprehensive analysis of the detailed natural course, treatment, and cli...
embolization; microsurgery; prognosis; spinal cord arteriovenous shunts; vascular disorders
1.354
244
Neurology; Surgery
Medicine
2,024
38,941,647
Vestibular evaluation with video head impulse test in pediatric cochlear implant patients.
Boletin medico del Hospital Infantil de Mexico
Bol Med Hosp Infant Mex
81
3
10.24875/BMHIM.24000022
eng
2,024
null
null
null
null
null
[BACKGROUND] The cochlear implant (CI) is effective for rehabilitating patients with severe to profound sensorineural hearing loss. However, its placement and use have been associated with various complications, such as those affecting the vestibular system. The objective of this study was to compare vestibular functio...
Cochlear implant; Hearing loss; Hipoacusia; Implante coclear; Vestibular function; Video head impulse test; v-HIT
null
null
null
null
null
38,941,004
Outcomes of oocyte retrievals completed by reproductive endocrinology and infertility fellows versus faculty: a 7-year retrospective review.
Journal of assisted reproduction and genetics
J Assist Reprod Genet
41
8
10.1007/s10815-024-03177-8
eng
2,024
8
null
2,024
6
28
[PURPOSE] To examine outcomes of oocyte retrievals completed by Reproductive Endocrinology and Infertility (REI) fellows versus faculty physicians. [METHODS] This retrospective cohort study examined patients who underwent oocyte retrievals at Mayo Clinic from July 15, 2009, to December 15, 2016. The primary outcome was...
Fellow; Fellowship; Learning curve; Oocyte aspiration; Oocyte retrieval
0.868
101
Obstetrics and Gynecology; Developmental Biology; Genetics; Genetics; Medicine; Reproductive Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,940,924
Translation and cultural adaptation of the Italian version of the Paediatric Palliative Screening Scale.
European journal of pediatrics
Eur J Pediatr
183
9
10.1007/s00431-024-05649-6
eng
2,024
9
null
2,024
6
28
[UNLABELLED] The number of children eligible for Paediatric Palliative Care has dramatically increased over the years, with few tools that can help with early identification. The Paediatric Palliative Screening Scale is a dedicated German, English, and Portuguese screening tool. We aimed to translate and perform a cult...
Assessment needs; Children; Family; Palliative care
0.934
115
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,940,815
The perception of air pollution and its health risk: a scoping review of measures and methods.
Global health action
Glob Health Action
17
1
10.1080/16549716.2024.2370100
eng
2,024
12
31
2,024
6
28
[BACKGROUND] Although there is increasing awareness of the health risks of air pollution as a global issue, few studies have focused on the methods for assessing individuals' perceptions of these risks. This scoping review aimed to identify previous research evaluating individuals' perceptions of air pollution and its ...
Air pollution; air quality; awareness; health risk; health risk perception; standardised scales
0.983
76
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,024
38,940,548
Health-related quality of life instrument with 8 items to measure health-related quality of life among family caregivers of people with dementia: A pilot validation study.
Public health nursing (Boston, Mass.)
Public Health Nurs
41
5
10.1111/phn.13368
eng
2,024
null
null
2,024
6
28
[BACKGROUND] The health-related quality of life instrument with 8 items (HINT-8) was developed to measure health-related quality of life (HRQoL) in Korea. However, the HINT-8 has not yet been validated among the family caregivers of people with dementia (PwD). [DESIGN] A cross-sectional pilot study. [OBJECTIVE] The stu...
caregivers; dementia; family; validation study
0.723
63
Nursing; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,024
38,940,471
Sleep as a contributor to socioeconomic disparities in hypertension: The Midlife in the United States (MIDUS II) Study.
Sleep
Sleep
47
9
10.1093/sleep/zsae142
eng
2,024
9
9
null
null
null
[STUDY OBJECTIVES] Hypertension is highly prevalent and is a major risk factor for cardiovascular disease. There is a higher burden of hypertension among individuals of lower socioeconomic status (SES), yet the role of sleep in understanding socioeconomic disparities in hypertension is unclear. We investigated whether ...
education; health disparities; hypertension; sleep; social determinants of health; socioeconomic status
1.796
248
Behavioral Neuroscience; Clinical Psychology; Neurology; Neuropsychology and Physiological Psychology; Physiology
Medicine; Neuroscience; Psychology
2,024
38,940,449
Current status of advance care planning, palliative care consultation, and end-of-life care in patients with glioblastoma in South Korea.
The oncologist
Oncologist
29
11
10.1093/oncolo/oyae159
eng
2,024
11
4
null
null
null
[BACKGROUND] Given the typical trajectory of glioblastoma, many patients lose decision-making capacity over time, which can lead to inadequate advance care planning (ACP) and end-of-life (EOL) care. We aimed to evaluate patients' current ACP and EOL care status. [PATIENTS AND METHODS] We conducted a cohort study on 205...
advance care planning; end-of-life care; glioblastoma; goal-concordant care; palliative care consultation
2.329
199
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,940,447
Is older age an appropriate criterion alone for ordering cervical spine computed tomography after trauma.
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
Acad Emerg Med
32
4
10.1111/acem.14976
eng
2,025
4
null
2,024
6
28
[BACKGROUND] Cervical spine computed tomography (CSCT) scans are frequently performed in older emergency department (ED) trauma patients based on the 65-year-old high-risk criterion of the Canadian Cervical Spine Rule (CCR). We sought to determine the positivity rate of CSCT scans in symptomatic and asymptomatic patien...
age; cervical spine; computed tomography; fracture; trauma
1.225
148
Emergency Medicine; Medicine
Medicine
2,024
38,939,927
Safety of Selective Operative Drainage After Pancreatic Resection: A Retrospective Analysis of 2,607 Patients.
Annals of surgery
Ann Surg
null
null
10.1097/SLA.0000000000006425
eng
2,024
6
28
2,024
6
28
[OBJECTIVE] To assess whether selective omission of operative drains after pancreaticoduodenectomy (PD) and distal pancreatectomy (DP) is associated with adverse perioperative outcomes. [BACKGROUND] The routine use of operative drains after pancreatectomy is widely practiced; however, prospective randomized clinical tr...
null
2.593
360
Surgery
Medicine
2,024
38,939,536
Deep margin elevation in class II cavities: A comparative evaluation of microleakage and interface integrity using confocal laser microscopy and scanning electron microscopy.
Journal of conservative dentistry and endodontics
J Conserv Dent Endod
27
5
10.4103/JCDE.JCDE_155_24
eng
2,024
5
null
2,024
5
10
[AIM] This study aims to evaluate the microleakage between the gingival seat and base material and to assess the interface integrity between the base material and overlying composite in class II cavities restored using deep margin elevation. [MATERIALS AND METHODS] Thirty maxillary molars (n = 30) were taken, and class...
Deep margin elevation; interface integrity; microleakage; scanning electron microscopy
0.66
48
Dentistry
Dentistry
2,024
38,939,288
Exploring the Relationship Between Helicobacter pylori Infection and Biliary Diseases: A Comprehensive Analysis Using the United States National Inpatient Sample (2016-2020).
Cureus
Cureus
16
5
10.7759/cureus.61238
eng
2,024
5
null
2,024
5
28
[BACKGROUND] Helicobacter pylori (H. pylori) infection is widely recognized for its association with gastric diseases. Prior studies on the relationship between H. pylori infection and biliary diseases have faced constraints, including inadequate control of confounding factors and small sample sizes. This study aims to...
biliary diseases; cholecystitis; gallbladder cancer; gallstones; helicobacter pylori; national inpatient sample
null
null
null
null
null
38,939,096
Protection of Gueichih-Fuling-Wan on cerebral ischemia-induced brain injury in rodents is mediated by trans-cinnamaldehyde via inhibition of neuroinflammation and apoptosis.
BioMedicine
Biomedicine (Taipei)
14
2
10.37796/2211-8039.1449
eng
2,024
null
null
2,024
6
1
[BACKGROUND] Stroke is the leading cause of mortality and morbidity worldwide, and an effective therapeutic strategy for the prevention of patients with cerebral ischemia induced brain injury is lacking. Traditional Chinese medicine with neuroprotective activities might be beneficial and provide alternative therapeutic...
Cerebral; Gueichih-Fuling-Wan (GFW); Ischemia; Neuroinflammation and apoptosis; Neuroprotection; Trans-cinnamaldehyde (TCA)
null
null
null
null
null
38,939,039
A Transcriptomic Biomarker Predicting Linezolid-Associated Neuropathy During Treatment of Drug-Resistant Tuberculosis.
Pathogens & immunity
Pathog Immun
9
2
10.20411/pai.v9i2.705
eng
2,024
null
null
2,024
6
25
[BACKGROUND] Neuropathic adverse events occur frequently in linezolid-containing regimens, some of which remain irreversible after drug discontinuation. [OBJECTIVE] We aimed to identify and validate a host RNA-based biomarker that can predict linezolid-associated neuropathy before multidrug-resistant/rifampicin-resista...
SBSN; adverse events; linezolid; multidrug resistance; neurotoxicity; precision medicine; tuberculosis
null
null
null
null
null
38,938,468
Neural activation during natural speech and rests in patients with schizophrenia and schizophrenia spectrum disorders-an fMRI pilot trial.
Frontiers in psychiatry
Front Psychiatry
15
null
10.3389/fpsyt.2024.1402818
eng
2,024
null
null
2,024
6
13
[BACKGROUND] In schizophrenia patients, spontaneous speech production has been hypothesized as correlating with right hemispheric activation, including the inferior frontal and superior temporal gyri as speech-relevant areas. However, robust evidence for this association is still missing. The aim of the present fMRI st...
fMRI; psychopathology; rest; schizophrenia; spontaneous speech
1.192
134
Psychiatry and Mental Health
Medicine
2,024
38,938,379
Association of serum ferritin and all-cause mortality in AKI patients: a retrospective cohort study.
Frontiers in medicine
Front Med (Lausanne)
11
null
10.3389/fmed.2024.1368719
eng
2,024
null
null
2,024
6
13
[BACKGROUND] Serum ferritin (SF) is clinically found to be elevated in many disease conditions, and our research examines serum ferritin in patients with acute kidney injury (AKI) and its implication on the risk of short-term mortality in AKI. [METHODS] Data were extracted from the Medical Information Mart for Intensiv...
acute kidney injury; critical ill patient; hyperferritinemia; mortality; serum ferritin
0.962
102
Medicine
Medicine
2,024
38,937,943
A survey of emergency medical service providers' perspectives regarding relatives influence on acute prehospital treatment of adult patients.
Acta anaesthesiologica Scandinavica
Acta Anaesthesiol Scand
68
9
10.1111/aas.14480
eng
2,024
10
null
2,024
6
27
[BACKGROUND] In the field of prehospital emergency medicine, specialized emergency medical service (EMS) providers interact with acutely ill patients and their relatives. The influence of family presence during in-hospital resuscitation is well described. However, no studies have previously assessed the influence of re...
emergency medicine; emergency medicine providers; family presence during resuscitation; prehospital; prehospital emergency medicine; relatives presence
0.749
126
Anesthesiology and Pain Medicine; Medicine
Medicine
2,024
38,937,900
Impact of cannabidiol on myocardial recovery in patients with acute myocarditis: Rationale & design of the ARCHER trial.
ESC heart failure
ESC Heart Fail
11
5
10.1002/ehf2.14889
eng
2,024
10
null
2,024
6
27
[AIMS] Acute myocarditis, although a rare disease, can be associated with sudden cardiac death or the need for transplantation in both children and young adults. To date, there is no definitive evidence to support the routine use of immunosuppressive therapy or treatment targeting inflammation in patients with myocardi...
CMR; Cannabidiol; Myocarditis; Randomized trial
1.403
57
Cardiology and Cardiovascular Medicine
Medicine
2,024
38,937,870
Using FRAME to adapt an evidence-based dyadic intervention program for people living with dementia in residential aged care: A pilot feasibility study.
Australian occupational therapy journal
Aust Occup Ther J
71
6
10.1111/1440-1630.12978
eng
2,024
12
null
2,024
6
27
[INTRODUCTION] The purpose of this study was to examine the feasibility of adapting and translating an evidence-based occupational therapist-delivered program shown to be effective in the community to residential aged care (RAC). The program aims to improve quality of care and quality of life for people living with dem...
activity participation; carer; dementia; feasibility study; occupational therapy; quality of life; reablement; residential aged care
0.65
56
Occupational Therapy
Health Professions
2,024
38,937,836
The relationship of immune cells with autism spectrum disorder: a bidirectional Mendelian randomization study.
BMC psychiatry
BMC Psychiatry
24
1
10.1186/s12888-024-05927-5
eng
2,024
6
27
2,024
6
27
[BACKGROUND] Observational studies have indicated a correlation between immunological inflammation and the risk of autism spectrum disorder (ASD). However, the causal relationship between immunological inflammation and ASD remains uncertain. [METHODS] Immunity-wide data sources were retrieved from the GWAS catalog. Gen...
ASD; Genetics; Immunity; Mendelian Randomization; SNPs
1.375
151
Psychiatry and Mental Health
Medicine
2,024
38,937,668
penalizedclr: an R package for penalized conditional logistic regression for integration of multiple omics layers.
BMC bioinformatics
BMC Bioinformatics
25
1
10.1186/s12859-024-05850-2
eng
2,024
6
27
2,024
6
27
[BACKGROUND] The matched case-control design, up until recently mostly pertinent to epidemiological studies, is becoming customary in biomedical applications as well. For instance, in omics studies, it is quite common to compare cancer and healthy tissue from the same patient. Furthermore, researchers today routinely c...
Conditional logistic regression; Multiple blocks of predictors/features; Stability selection
1.19
251
Applied Mathematics; Biochemistry; Computer Science Applications; Molecular Biology; Structural Biology
Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics
2,024
38,937,146
Development and Initial Validation of the Novel Scleroderma Clinical Trials Consortium Activity Index.
Arthritis & rheumatology (Hoboken, N.J.)
Arthritis Rheumatol
76
11
10.1002/art.42939
eng
2,024
11
null
2,024
8
26
[OBJECTIVE] Accurate measurement of disease activity in systemic sclerosis (SSc) remains a significant clinical challenge. The Scleroderma Clinical Trials Consortium (SCTC) convened an Activity Index (AI) Working Group (WG) to develop a novel measure of disease activity (SCTC-AI). [METHODS] Using consensus methodology,...
null
null
null
null
null
null
38,936,920
Association of Matrix Metalloproteinase-9 Genotypes With Nasopharyngeal Carcinoma Risk.
In vivo (Athens, Greece)
In Vivo
38
4
10.21873/invivo.13623
eng
2,024
null
null
null
null
null
[BACKGROUND/AIM] The up-regulation of matrix metalloproteinase-9 (MMP-9) expression is a characteristic feature observed across various malignancies, including nasopharyngeal carcinoma (NPC). Nevertheless, the influence of MMP-9 genotype in the context of NPC remains underexplored. This study examined the implications ...
Genotype; Taiwan; matrix metalloproteinase-9; nasopharyngeal carcinoma; polymorphism
null
null
null
null
null
38,936,917
Personalizing Prophylactic Radiotherapy for Hip Heterotopic Ossification: An AMSTAR-2 Compliant Review of Meta-analyses.
In vivo (Athens, Greece)
In Vivo
38
4
10.21873/invivo.13603
eng
2,024
null
null
null
null
null
[BACKGROUND/AIM] Heterotopic ossification (HO) is a common complication following total hip arthroplasty. Various prophylactic treatments have been proposed, including radiotherapy (RT). This review summarizes the evidence from meta-analyses on the efficacy of RT in preventing hip HO. [MATERIALS AND METHODS] A literatu...
Heterotopic ossification; hip; intensity-modulated radiation therapy; prophylaxis; radiotherapy; review
null
null
null
null
null
38,936,784
Fusobacterium nucleatum-infected periodontitis promotes renal interstitial fibrosis in rats through the TGF-β/SMAD2/3 and β-catenin signaling pathways.
Gene
Gene
927
null
10.1016/j.gene.2024.148729
eng
2,024
11
15
2,024
6
25
[OBJECTIVES] Periodontitis is associated with Fusobacterium nucleatum (F.n) infection. Although the colonization of renal tissue by F.n is well documented, its specific role in kidney disease has yet to be determined. This study aimed to investigate the potential association between F.n-induced periodontitis and renal ...
Epithelial-mesenchymal transition; Fusobacterium nucleatum; Periodontitis; Renal interstitial fibrosis
0.682
200
Medicine; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,936,745
CS12192: A novel selective and potent JAK3 inhibitor mitigates acute graft-versus-host disease in bone marrow transplantation.
Transplant immunology
Transpl Immunol
85
null
10.1016/j.trim.2024.102075
eng
2,024
8
null
2,024
6
25
[BACKGROUND] Despite the significant role of JAK3 in various autoimmune diseases, including graft-versus-host disease (GVHD), there has been a lack of potent and selective JAK3 inhibitors specifically studied for GVHD. In our preclinical investigations, we evaluated a novel JAK3 inhibitor called CS12192, which is alrea...
Autoimmune diseases; BMT; CS12192; GVHD; JAK/STAT
0.458
68
Transplantation; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
38,936,646
"Effects of threshold respiratory muscle training on respiratory muscle strength, pulmonary function and exercise endurance after stroke: a meta-analysis".
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
33
8
10.1016/j.jstrokecerebrovasdis.2024.107837
eng
2,024
8
null
2,024
6
25
[BACKGROUND] Most studies on improvements in respiratory muscle strength, activities of daily living (ADL) and quality of life (QoL) in stroke patients receiving threshold respiratory muscle training (TRMT) have small sample sizes, and some studies have contradictory results. [OBJECTIVES] To evaluate the effectiveness ...
Meta-analysis; Pulmonary function; Respiratory muscle strength; Stroke; Threshold respiratory muscle training
0.688
85
Rehabilitation; Cardiology and Cardiovascular Medicine; Neurology; Surgery
Medicine
2,024
38,936,609
A Long-Term Outcome of Symptomatic Middle Cerebral Artery Undergoing Intracranial Angioplasty or Stenting.
World neurosurgery
World Neurosurg
190
null
10.1016/j.wneu.2024.06.114
eng
2,024
10
null
2,024
6
25
[OBJECTIVE] For symptomatic stenosis in the middle cerebral artery (MCA), intracranial angioplasty and stenting are frequently employed. However, limited data exist regarding their long-term impact. Our study demonstrates the long-term advantages in preventing ischemic events through a 5-year follow-up period. [METHODS...
Atherosclerosis; Intracranial angioplasty; Middle cerebral artery; Stenting
0.709
123
Neurology; Surgery
Medicine
2,024
38,936,419
A Systematic Review of Clinical Outcomes of Pedicled Flap Repairs of the Knee Extensor Mechanism.
Journal of reconstructive microsurgery
J Reconstr Microsurg
41
4
10.1055/a-2355-4073
eng
2,025
5
null
2,024
6
27
[BACKGROUND] Rupture of the extensor mechanism of the knee has severe functional morbidity, and repair can be complicated by infection, allograft degeneration, and recurrent rupture. Techniques of autologous tissue repair utilizing pedicled flaps such as the gastrocnemius offer vascularized methods of reconstruction, w...
null
1.063
66
Surgery
Medicine
2,024
38,935,559
Circulating Metabolite Biomarkers of Glycemic Control in Youth-Onset Type 2 Diabetes.
Diabetes care
Diabetes Care
47
9
10.2337/dc23-2441
eng
2,024
9
1
null
null
null
[OBJECTIVE] We aimed to identify metabolites associated with loss of glycemic control in youth-onset type 2 diabetes. [RESEARCH DESIGN AND METHODS] We measured 480 metabolites in fasting plasma samples from the TODAY (Treatment Options for Type 2 Diabetes in Adolescents and Youth) study. Participants (N = 393; age 10-1...
null
6.566
433
Advanced and Specialized Nursing; Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine; Nursing
2,024
38,935,227
Prevalence and risk factors of extended-spectrum beta-lactamase producing E. coli causing urinary tract infections in Iceland during 2012-2021.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Eur J Clin Microbiol Infect Dis
43
9
10.1007/s10096-024-04882-z
eng
2,024
9
null
2,024
6
27
[PURPOSE] To investigate the association of potential risk factors for urinary tract infections (UTI) caused by E. coli producing ESBL vs. not producing ESBL in Iceland. [METHODS] Observational, case-control study including a cohort of 27,747 patients (22,800 females, 4,947 males; 1207 cases, 26,540 controls) of all ag...
Escherichia coli; Antibiotics; Antimicrobial agents; Antimicrobial resistance; Beta-lactamases; Risk factors; Urinary tract infections
null
null
null
null
null
38,935,218
cGMP compliant one-step, one-pot automated [[18]F]FBnTP production for clinical imaging of mitochondrial activity.
EJNMMI radiopharmacy and chemistry
EJNMMI Radiopharm Chem
9
1
10.1186/s41181-024-00274-y
eng
2,024
6
27
2,024
6
27
[BACKGROUND] 4-[[18]F]fluorobenzyl-triphenylphosphonium ([[18]F]FBnTP) is a lipophilic cation PET tracer. The cellular uptake of [[18]F]FBnTP is correlated with oxidative phosphorylation by mitochondria, which has been associated with multiple critical diseases. To date, [[18]F]FBnTP has been successfully applied for i...
Automation; PET; Radiopharmaceutical; [18F]FBnTP
null
null
null
null
null
38,935,140
Modelling impacts of a salt and sugar tax on hypothetical intra-category food substitutions, BMI and environmental footprints in the UK population.
European journal of nutrition
Eur J Nutr
63
7
10.1007/s00394-024-03452-5
eng
2,024
10
null
2,024
6
27
[PURPOSE] Taxes on unhealthy foods can help improve population health in the United Kingdom (UK), but the health effects of food substitutions resulting from these taxes are often unclear. We investigated the potential impacts of a salt and sugar tax on hypothetical intra-category food substitutions, cost, body-mass in...
Environmental sustainability; Fiscal measures; Food expenditures; Health promotion; Obesity reduction
1.346
125
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
38,935,114
Comprehensive analysis of cuproptosis-related genes involved in immune infiltration and their use in the diagnosis of hepatic ischemia-reperfusion injury: an experimental study.
International journal of surgery (London, England)
Int J Surg
111
1
10.1097/JS9.0000000000001893
eng
2,025
1
1
2,025
1
1
[BACKGROUND] Hepatic ischemia-reperfusion injury (HIRI) is a common injury not only during liver transplantation but also during major hepatic surgery. HIRI causes severe complications and affects the prognosis and survival of patients. Cuproptosis, a newly identified form of cell death, plays an important role in a va...
null
2.076
99
Medicine; Surgery
Medicine
2,024
38,935,086
Favorable prostate-specific antigen levels correlate with a worse prognosis in high-grade prostate cancer: a population-based analysis.
International journal of surgery (London, England)
Int J Surg
111
1
10.1097/JS9.0000000000001884
eng
2,025
1
1
2,025
1
1
[BACKGROUND] To compare the association between prostate-specific antigen (PSA) levels and prostate cancer-specific mortality (PCSM) and the effectiveness of local treatment in patients with high-grade and low-grade prostate cancer (PCa). [METHODS] This retrospective cohort study enrolled patients diagnosed with clinic...
null
2.076
99
Medicine; Surgery
Medicine
2,024
38,934,979
Reappraisal of the Concept and Implications of Pulmonary Hypertension in Degenerative Mitral Regurgitation.
JACC. Cardiovascular imaging
JACC Cardiovasc Imaging
17
10
10.1016/j.jcmg.2024.05.006
eng
2,024
10
null
2,024
6
26
[BACKGROUND] European and U.S. clinical guidelines diverge regarding pulmonary hypertension (PHTN) in degenerative mitral regurgitation (DMR). Gaps in knowledge underpinning these divergences affect risk assessment and management recommendations attached to systolic pulmonary pressure (SPAP) in DMR. [OBJECTIVES] This s...
degenerative mitral regurgitation; echocardiography; mitral valve prolapse; pulmonary hypertension; survival
null
null
null
null
null
38,934,523
Pentoxifylline treatment as a safe method for selecting viable testicular spermatozoa before cryopreservation of a small numbers of spermatozoa in azoospermia individuals.
Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
Arch Ital Urol Androl
96
2
10.4081/aiua.2024.12525
eng
2,024
6
27
2,024
6
27
[BACKGROUND] Single sperm cryopreservation (SSC) is a specific technique especially used in individuals with small numbers of sperm who suffered from non-obstructive azoospermia (NOA). Testicular specimens possess poor motility and low population of viable spermatozoa. Therefore, sperm selection methods such as applyin...
null
null
null
null
null
null
38,934,016
Experiential Learning with Ketamine: A Mixed-Methods Exploratory Study on Prescription and Perception.
Therapeutics and clinical risk management
Ther Clin Risk Manag
20
null
10.2147/TCRM.S462760
eng
2,024
null
null
2,024
6
21
[BACKGROUND] Incorporating unfamiliar therapies into practice requires effective longitudinal learning and the optimal way to achieve this is debated. Though not a novel therapy, ketamine in critical care has a paucity of data and variable acceptance, with limited research describing intensivist perceptions and utiliza...
analgosedation; continuing education; critical care; ketamine; learning theory
0.699
74
Pharmacology, Toxicology and Pharmaceutics; Safety Research; Chemical Health and Safety; Medicine; Pharmacology
Chemical Engineering; Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,024
38,933,977
In vivo comparison of customized zirconia barriers in guided bone regeneration: An experimental study.
Heliyon
Heliyon
10
11
10.1016/j.heliyon.2024.e32070
eng
2,024
6
15
2,024
6
3
[OBJECTIVE] This study aims to evaluate the effects of customized zirconia barrier membranes produced for guided bone regeneration (GBR) approaches on bone healing researched with histological and histomorphometric methods. [METHODS] The digital modeling was used to create zirconia barrier membranes suitable for the de...
Bone regeneration; Customized CAD/CAM-manufactured membranes; Non-resorbable membranes; Titanium; Zirconia
0.644
115
Multidisciplinary
Multidisciplinary
2,024
38,933,885
Nonlinear relationship between serum 25-hydroxyvitamin D and lipid profile in Chinese adults.
Frontiers in nutrition
Front Nutr
11
null
10.3389/fnut.2024.1388017
eng
2,024
null
null
2,024
6
12
[BACKGROUND] Previous studies on the liner associations between serum 25-hydroxyvitamin D [25(OH)D] levels and lipid profiles revealed ambiguous findings. The current study therefore tried to elucidate the possible non-linear associations between 25(OH)D and lipid profiles. [METHODS] This study involved 8,516 adult par...
25-hydroxyvitamin D; cholesterol; lipid profile; non-linear; threshold
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
38,932,894
Association of CIITA (rs8048002) and CLEC2D (rs2114870) gene variants and type 1 diabetes mellitus.
Journal of diabetes and metabolic disorders
J Diabetes Metab Disord
23
1
10.1007/s40200-024-01402-w
eng
2,024
6
null
2,024
4
18
[BACKGROUND] Type I diabetes mellitus (T1DM) is a significant health challenge, especially for children, owing to its chronic autoimmune nature. Although the exact etiology of T1DM remains elusive, the interplay of genetic predisposition, immune responses, and environmental factors are postulated. Genetic factors contr...
CIITA gene (rs8048002); CLEC2D (rs2114870; RegulomeDB; Single nucleotide polymorphisms; T1DM; TaqMan genotyping
0.534
49
Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,024
38,931,891
Heparin Dosing Regimen Optimization in Veno-Arterial Extracorporeal Membrane Oxygenation: A Pharmacokinetic Analysis.
Pharmaceutics
Pharmaceutics
16
6
10.3390/pharmaceutics16060770
eng
2,024
6
6
2,024
6
6
[BACKGROUND] Unfractionated heparin is administered in patients undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Anticoagulation monitoring is recommended, with an anti-activated factor X (anti-Xa) targeting 0.3 to 0.7 IU/mL. Owing to heparin's heterogeneous pharmacokinetic properties, anti-Xa is...
anti-Xa; anticoagulation; extracorporeal membrane oxygenation (ECMO); heparin; pharmacokinetics
null
null
null
null
null
38,931,274
Nutritional Behavior of Patients with Bone Diseases: A Cross-Sectional Study from Austria.
Nutrients
Nutrients
16
12
10.3390/nu16121920
eng
2,024
6
18
2,024
6
18
[BACKGROUND] A balanced diet rich in calcium and protein is recommended for bone-healthy people and osteoporosis patients, but it may also be important for rare bone disease (RBD). Little data is available on RBD and diet. Therefore, the aim of this study was to evaluate the nutritional behavior of patients with RBD. [...
X-linked hypophosphatemia; hypophosphatasia; nutrition; osteogenesis imperfecta; osteoporosis; rare bone disease; vitamin D
1.473
243
Food Science; Nutrition and Dietetics
Agricultural and Biological Sciences; Nursing
2,024
38,930,918
Cerium Dioxide-Dextran Nanocomposites in the Development of a Medical Product for Wound Healing: Physical, Chemical and Biomedical Characteristics.
Molecules (Basel, Switzerland)
Molecules
29
12
10.3390/molecules29122853
eng
2,024
6
15
2,024
6
15
[PURPOSE OF THE STUDY] the creation of a dextran coating on cerium oxide crystals using different ratios of cerium and dextran to synthesize nanocomposites, and the selection of the best nanocomposite to develop a nanodrug that accelerates quality wound healing with a new type of antimicrobial effect. [MATERIALS AND ME...
antimicrobial activity; cerium dioxide; dextran; fibroblasts; gas chromatography; nanocerium; nanocomposite; nanodrug; nanoparticles; polysaccharide; regeneration; wound healing
0.865
261
Analytical Chemistry; Chemistry; Organic Chemistry; Pharmaceutical Science; Physical and Theoretical Chemistry; Drug Discovery; Medicine; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,930,526
Filling the Knowledge Gap Regarding Microbial Occupational Exposure Assessment in Waste Water Treatment Plants: A Scoping Review.
Microorganisms
Microorganisms
12
6
10.3390/microorganisms12061144
eng
2,024
6
4
2,024
6
4
[BACKGROUND] Wastewater treatment plants (WWTPs) are crucial in the scope of European Commission circular economy implementation. However, bioaerosol production may be a hazard for occupational and public health. A scoping review regarding microbial contamination exposure assessment in WWTPs was performed. [METHODS] Th...
assays; bacteria; fungi; microbial contamination assessment; sampling methods; wastewater treatment plants
1.009
112
Microbiology; Microbiology; Virology
Immunology and Microbiology; Medicine
2,024
38,929,881
Chronic Pelvic Pain in Congestion Pelvic Syndrome: Clinical Impact and Electromyography Pelvic Floor Activity Prior to and after Endovascular Treatment.
Journal of personalized medicine
J Pers Med
14
6
10.3390/jpm14060661
eng
2,024
6
20
2,024
6
20
[BACKGROUND] This study aims to characterize the clinical impact of endovascular treatment in Chronic Pelvic Pain (CPP) patients due to Pelvic Congestion Syndrome (PCS) and to assess the diagnostic value of surface electromyography (sEMG) studies of pelvic floor musculature (PFM) in PCS patients pre- and post-endovascu...
chronic pelvic pain; congestion pelvic syndrome; electromyography; pelvic floor activity; sclero-embolization
0.863
62
Medicine
Medicine
2,024
38,929,849
Sequence Alignment between TRIM33 Gene and Human Noncoding RNAs: A Potential Explanation for Paraneoplastic Dermatomyositis.
Journal of personalized medicine
J Pers Med
14
6
10.3390/jpm14060628
eng
2,024
6
13
2,024
6
13
[BACKGROUND] This computational analysis investigated sequence complementarities between the TRIM33 gene and human noncoding (nc)RNAs and characterized their interactions in the context of paraneoplastic dermatomyositis. [METHODS] TRIM33 FASTA sequence (NCBI Reference Sequence: NC_000001.11) was used for BLASTN analysi...
TRIM33; bioinformatics; cancer; dermatomyositis; ncRNAs
0.863
62
Medicine
Medicine
2,024
38,929,323
Contribution of Treatment with Ear Popper for Hearing in Children with Middle Ear Effusion.
Children (Basel, Switzerland)
Children (Basel)
11
6
10.3390/children11060744
eng
2,024
6
18
2,024
6
18
[OBJECTIVES] we aim to assess the contribution of the EarPopper device to hearing in children with middle ear effusion (MEE). [METHODS] The study has three parts, including 1. tympanometry and audiometry before and six weeks after using the EarPopper to evaluate the treatment's effect over time compared to a control gr...
EarPopper; auto inflation; middle ear effusion; tympanometry
0.674
56
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,927,343
Impact of Early Surfactant Administration on Ductus Arteriosus Assessed at 24 h in Preterm Neonates Less than 32 Weeks of Gestational Age.
Biomedicines
Biomedicines
12
6
10.3390/biomedicines12061136
eng
2,024
5
21
2,024
5
21
[BACKGROUND AND OBJECTIVES] The purpose of this study was to investigate whether early surfactant administration affects the status of ductus arteriosus (DA) in preterm infants ≤ 32 weeks of gestational age (GA) within 24 h of birth. [MATERIALS AND METHODS] It is a prospective study conducted from 1 March 2022 to 31 De...
ductus arteriosus; echographic parameters; preterm infants; surfactant
1.114
85
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,926,656
The effect of late presentation on HIV related mortality among adolescents in public hospitals of north showa zone Oromiya, Ethiopia; 2022: a retrospective cohort study.
BMC infectious diseases
BMC Infect Dis
24
1
10.1186/s12879-024-09550-3
eng
2,024
6
26
2,024
6
26
[BACKGROUND] Late human immunodeficiency virus (HIV) diagnosis is the most prominent cause of HIV/AIDS-related mortality and also increases the risk of transmission and spread of the disease in society. Adolescents are the most vulnerable population's age group for HIV infection in several settings, but expanding acces...
Adolescence; Ethiopia; HIV-related mortality; Late presentation
1.035
137
Infectious Diseases
Medicine
2,024
38,926,058
RAS-activated PI3K/AKT signaling sustains cellular senescence via P53/P21 axis in experimental models of psoriasis.
Journal of dermatological science
J Dermatol Sci
115
1
10.1016/j.jdermsci.2024.03.002
eng
2,024
7
null
2,024
3
7
[BACKGROUND] Psoriasis is a chronic immune-mediated skin disease in which upper epidermal keratinocytes exhibit a senescent-like phenotype. In psoriatic skin, a variety of inflammatory cytokines can activate intracellular pathways including phosphatidylinositol 3-kinase (PI3K)/AKT signaling and RAS effectors. AKT and R...
AKT; Keratinocytes; Psoriasis; RAS; Senescence
1.082
115
Dermatology; Biochemistry; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,925,656
The impact of lifestyle on cardiovascular risk in patients with gout: a population-based cohort study.
European heart journal. Quality of care clinical outcomes
Eur Heart J Qual Care Clin Outcomes
11
4
10.1093/ehjqcco/qcae048
eng
2,025
6
23
null
null
null
[AIMS] Gout is associated with a significant burden of cardiovascular disease. The aim of this study was to evaluate the impact of a favourable lifestyle on incident cardiovascular events in patients with gout. [METHODS] We identified 9 110 patients with gout from the UK Biobank cohort based on self-report and/or hospi...
Cardiovascular risk; Gout; Lifestyle behaviour; Uric acid
null
null
null
null
null
38,924,994
The features of male breast cancer in China: A real-world study.
Breast (Edinburgh, Scotland)
Breast
76
null
10.1016/j.breast.2024.103762
eng
2,024
8
null
2,024
6
22
[BACKGROUND] Male breast cancer (MBC) is a rare disease. Although several large-scale studies have investigated MBC patients in other countries, the features of MBC patients in China have not been fully explored. This study aims to explore the features of Chinese MBC patients comprehensively. [METHODS] We retrospective...
Characteristics; China; Male breast cancer; Prognosis; Treatment
2.348
106
Cancer Research; Medicine; Oncology; Surgery
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,924,897
Preoperative depression is an independent risk factor for short-term morbidities in autologous and implant-based breast reconstruction.
Journal of plastic, reconstructive aesthetic surgery : JPRAS
J Plast Reconstr Aesthet Surg
95
null
10.1016/j.bjps.2024.05.060
eng
2,024
8
null
2,024
6
13
[BACKGROUND] Depression is notably common among patients who have undergone mastectomy. Several post-mastectomy patients opt for elective breast reconstruction. However, evidence on the influence of preoperative depression on breast reconstruction outcomes remains limited. This study aimed to evaluate the effect of pre...
Autologous; Breast reconstruction; Complications; Depression; Implant
null
null
null
null
null
38,924,844
Evaluation of the correlation between trigeminal nerve atrophy and trigeminal neuralgia using multimodal image fusion: A single-center retrospective study.
Clinical neurology and neurosurgery
Clin Neurol Neurosurg
243
null
10.1016/j.clineuro.2024.108387
eng
2,024
8
null
2,024
6
14
[BACKGROUND] 3D-Slicer is an open-source medical image processing and visualization software. In the surgical treatment of trigeminal neuralgia, it is commonly used to predict the responsible vessels. However, there are few reports on the use of 3D-Slicer software to quantitatively measure the bilateral trigeminal nerv...
3D-FIESTA; 3D-TOF-MRA; 3D-slicer; Offending vessel; Primary trigeminal neuralgia atrophy
0.594
89
Medicine; Surgery; Neurology
Medicine
2,024
38,924,830
Periodic limb movements during sleep in children with neuromuscular disease or cerebral palsy - An important potential contributor to sleep-related morbidity.
Sleep medicine
Sleep Med
121
null
10.1016/j.sleep.2024.06.017
eng
2,024
9
null
2,024
6
22
[OBJECTIVES] Poor sleep is frequently reported in children with neuromuscular diseases (NMD) and cerebral palsy (CP) however breathing disorders during sleep are often the clinical focus. Periodic limb movements (PLMs) have an increased prevalence in adults with NMD and may contribute to sleep disturbance in this popul...
Cerebral palsy; Duchenne muscular dystrophy; Myopathy; Neuromuscular; Periodic limb movement; Spinal muscular atrophy
1.231
159
Medicine
Medicine
2,024
38,924,731
Dupilumab for Eosinophilic Esophagitis in Patients 1 to 11 Years of Age.
The New England journal of medicine
N Engl J Med
390
24
10.1056/NEJMoa2312282
eng
2,024
6
27
null
null
null
[BACKGROUND] Dupilumab is a human monoclonal antibody that blocks interleukin-4 and interleukin-13 pathways and has shown efficacy in five different atopic diseases marked by type 2 inflammation, including eosinophilic esophagitis in adults and adolescents. [METHODS] In this phase 3 trial, we randomly assigned, in a 2:...
null
19.076
1,231
Medicine
Medicine
2,024
38,924,592
Integrative analysis reveals different feature of intrahepatic cholangiocarcinoma subtypes.
Liver international : official journal of the International Association for the Study of the Liver
Liver Int
44
9
10.1111/liv.16015
eng
2,024
9
null
2,024
6
25
[BACKGROUND AND AIMS] Intrahepatic cholangiocarcinoma (iCCA) has two main histological subtypes: large and small duct-type iCCA, which are characterized by different clinicopathological features. This study was conducted with the purpose of expanding our understanding of their differences in molecular features and immu...
PPP1R1B; intrahepatic cholangiocarcinoma
2.001
145
Hepatology
Medicine
2,024
38,924,140
Coping as a mediator of the relationship between kinesiophobia and illness perception in atrial fibrillation patients: A cross-sectional mediation analysis.
Journal of advanced nursing
J Adv Nurs
81
2
10.1111/jan.16262
eng
2,025
2
null
2,024
6
24
[AIM(S)] To explore the mediating role of coping styles in the association between illness perception and kinesiophobia in atrial fibrillation patients. [DESIGN] A cross-sectional survey. [METHODS] Between June 2021 and November 2022, data were collected using a self-designed demographic questionnaire, the Brief Illnes...
atrial fibrillation; illness perception; kinesiophobia; medical coping styles; nurse
1.398
187
Nursing
Nursing
2,024
38,924,113
Who's most at risk? A person-centered approach to understanding the long-term relationship between early social media use and later depression across adolescence.
Journal of adolescence
J Adolesc
96
7
10.1002/jad.12362
eng
2,024
10
null
2,024
6
26
[INTRODUCTION] Person-centered analyses examined the relationship between social media use and depression over an 8-year period. The purpose was to examine the varying ways early social media use was associated with the development of depressive symptoms with a hypothesis that social media would not have a uniform asso...
adolescence; depression; longitudinal; mixture modeling; social media
1.506
145
Developmental and Educational Psychology; Pediatrics, Perinatology and Child Health; Psychiatry and Mental Health; Social Psychology
Medicine; Psychology
2,024
38,923,662
Reconstructive surgery for women with female genital mutilation: A scoping review.
BJOG : an international journal of obstetrics and gynaecology
BJOG
131
12
10.1111/1471-0528.17886
eng
2,024
11
null
2,024
6
24
[BACKGROUND] Female genital mutilation (FGM) is a global public health concern. However, reconstructive surgery remains unavailable in many countries. [OBJECTIVES] This scoping review, guided by Joanna Briggs Institute (JBI) principles, explores indications, referral routes, eligibility, care pathways and clinical outc...
clitoral reconstruction; cutting; emotional support; female genital mutilation; labia reconstruction; model of care; outcome assessment; psychosexual counselling; psychosexual therapy; reconstructive surgery; referral pathway
1.786
195
Obstetrics and Gynecology
Medicine
2,024
38,923,267
Dezocine as preemptive analgesia alleviates ultrapulse CO2 fractional laser treatment induced pain in patients with acne scars.
Journal of cosmetic dermatology
J Cosmet Dermatol
23
10
10.1111/jocd.16410
eng
2,024
10
null
2,024
6
24
[BACKGROUND] Ultrapluse CO2 fractional laser technology has emerged as an effective treatment for scar management. However, one drawback of this modality is the pain caused during the procedure. This study aims to explore the efficacy and safety of dezocine (DZC) as preemptive analgesia for reduction of pain induced by...
acne scars; dezocine; reduction of pain; ultrapluse CO2 fractional laser
0.764
67
Dermatology
Medicine
2,024
38,923,248
Comparable results in total knee arthroplasty using the ROSA knee system versus the conventional technique: A retrospective propensity-matched cohort study.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Knee Surg Sports Traumatol Arthrosc
32
12
10.1002/ksa.12330
eng
2,024
12
null
2,024
6
23
[PURPOSE] Robotic-assisted total knee arthroplasty (RA-TKA) is an increasingly popular alternative that may increase the accuracy of conventional TKA techniques. This study aims to evaluate RA-TKA accuracy and compare its radiographic and clinical outcomes to conventional TKA (cTKA). [METHODS] A retrospective examinati...
ROSA; accuracy; robotic assisted system; total knee arthroplasty
1.95
160
Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,024
38,923,047
Athletic prognosis following arthroscopic removal of osteochondral fragments of the proximal dorsal sagittal ridge of the fetlock in Thoroughbreds intended for flat racing.
Veterinary surgery : VS
Vet Surg
53
6
10.1111/vsu.14129
eng
2,024
8
null
2,024
6
24
[OBJECTIVE] To establish racing prognosis in Thoroughbred yearlings with proximal sagittal ridge osteochondral lesions and compare them to dorsoproximal and palmar/plantar first phalanx osteochondral lesions. [ANIMALS] A total of 47 horses had proximal sagittal ridge lesions, 34 had palmar/plantar first phalanx lesions...
null
0.748
94
Veterinary
Veterinary
2,024
38,922,898
Comprehensive assessment of combined inorganic and organic fertilization strategies on cotton cultivation: implications for sustainable agriculture.
Journal of the science of food and agriculture
J Sci Food Agric
104
14
10.1002/jsfa.13673
eng
2,024
11
null
2,024
6
26
[BACKGROUND] The integration of inorganic and organic fertilizers is increasingly being recommended to address the demand for sustainable cotton cultivation and to mitigate the ecological impacts of reliance on inorganic fertilizers. However, the nuanced effects of this combined fertilization approach on soil quality, ...
cotton yield; organic fertilizer; soil quality; sustainable production
null
null
null
null
null
38,922,895
A cross-sectional study of academic success measures, grit, and resilience among US dental students.
Journal of dental education
J Dent Educ
88
11
10.1002/jdd.13627
eng
2,024
11
null
2,024
6
23
[PURPOSE] This study explored themes previously identified as central to holistic professional school success, as related to traditional academic achievement, resilience, and grit measures. [METHODS] This cross-sectional study surveyed third- and fourth-year US dental students. Items addressed themes previously identif...
academic performance; academic success; grit; predental; professional education; professional student; psychological psychometrics; resilience
0.496
83
Dentistry; Education; Medicine
Dentistry; Medicine; Social Sciences
2,024
38,922,339
Tumor-Agnostic Genomic and Clinical Analysis of BRAF Fusions Identifies Actionable Targets.
Clinical cancer research : an official journal of the American Association for Cancer Research
Clin Cancer Res
30
17
10.1158/1078-0432.CCR-23-3981
eng
2,024
9
3
null
null
null
[PURPOSE] Even though BRAF fusions are increasingly detected in standard multigene next-generation sequencing panels, few reports have explored their structure and impact on clinical course. [EXPERIMENTAL DESIGN] We collected data from patients with BRAF fusion-positive cancers identified through a genotyping protocol ...
null
4.8
392
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,920,241
Mitigating adverse social determinants of health in the vulnerable population: Insights from a home visitation programme.
Annals of the Academy of Medicine, Singapore
Ann Acad Med Singap
53
3
10.47102/annals-acadmedsg.2023119
eng
2,024
3
27
2,024
3
27
[INTRODUCTION] Low-income families are exposed to adverse childhood experiences and psychosocial risks that impact child development. At the KK Women's and Children's Hospital in Singapore, Kids Integrated Development Service (KIDS0-3) is a home visitation programme that aims to optimise the development of children fro...
adverse childhood experiences; child development outcomes; low-income families; maternal psychosocial risks; toxic stress
0.358
70
Medicine
Medicine
2,024
38,919,634
Assessing and managing patients with borderline personality disorder requesting medical assistance in dying.
Frontiers in psychiatry
Front Psychiatry
15
null
10.3389/fpsyt.2024.1364621
eng
2,024
null
null
2,024
6
11
[BACKGROUND] When physician assisted dying (referred to as Medical Assistance in Dying or MAiD in this article) is available for individuals with mental disorders as the sole underlying medical condition (MD-SUMC), patients with borderline personality disorder (BPD) frequently request MAiD. Psychiatrists and other clin...
assessment; borderline personality disorder; irremediability; management; medical assistance in dying; treatment resistant
1.192
134
Psychiatry and Mental Health
Medicine
2,024
38,919,606
Differences in risk of serious infections between patients with secondary versus primary nephropathy following rituximab treatment: a retrospective cohort study.
Frontiers in immunology
Front Immunol
15
null
10.3389/fimmu.2024.1390997
eng
2,024
null
null
2,024
6
11
[BACKGROUND] The incidence of severe infections (SIs) in patients with autoimmune nephropathy after rituximab (RTX) treatment varies significantly. Our study aims to identify high-risk populations, specifically by comparing the differences in the risk of SIs between patients with primary nephropathy and those with neph...
autoimmune kidney disease; risk factors; rituximab; secondary nephropathy; severe infection
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
38,919,512
Chronic Liver Enzyme Elevation and Use of Contemporary ARVs Among People With HIV.
Open forum infectious diseases
Open Forum Infect Dis
11
6
10.1093/ofid/ofae308
eng
2,024
6
null
2,024
6
8
[BACKGROUND] While use of some older antiretroviral drugs (ARVs) is associated with chronic liver enzyme elevation (cLEE), the impact of newer ARVs remains unknown. [METHODS] People with HIV enrolled in the RESPOND cohort who started an ARV after January 1, 2012 were included (baseline). The primary outcome was first c...
Chronic liver enzyme elevation (cLEE); HCV; ART; HIV
1.441
74
Infectious Diseases; Oncology
Medicine
2,024
38,919,392
Employing advanced supervised machine learning approaches for predicting micronutrient intake status among children aged 6-23 months in Ethiopia.
Frontiers in nutrition
Front Nutr
11
null
10.3389/fnut.2024.1397399
eng
2,024
null
null
2,024
6
11
[BACKGROUND] Although micronutrients (MNs) are important for children's growth and development, their intake has not received enough attention. MN deficiency is a significant public health problem, especially in developing countries like Ethiopia. However, there is a lack of empirical evidence using advanced statistica...
Ethiopia; children; machine learning algorithm; micronutrient supplementation; prediction
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
38,918,995
Virtual Screening, Molecular Dynamics Simulation, and Bioactivity Assessment Validate T13074 as a Dual-Target EGFR/c-Met Inhibitor.
Current medicinal chemistry
Curr Med Chem
null
null
10.2174/0109298673305941240605050450
eng
2,024
6
24
2,024
6
24
[OBJECTIVES] The objective of this study is to identify dual-target inhibitors against EGFR/c-Met through virtual screening, dynamic simulation, and biological activity evaluation. This endeavor is aimed at overcoming the challenge of drug resistance induced by L858R/T790M mutants. [METHODS] Active structures were gath...
EGFR resistance; ROC-based virtual screening; biological activity evaluation; c-Met; drug discovery; dynamic simulation.
0.778
210
Biochemistry; Drug Discovery; Molecular Medicine; Organic Chemistry; Pharmacology
Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
2,024
38,918,808
Locally advanced breast cancer patients should be cautious about the immediate breast reconstruction after mastectomy: a pooling analysis of safety and efficacy.
World journal of surgical oncology
World J Surg Oncol
22
1
10.1186/s12957-024-03444-z
eng
2,024
6
25
2,024
6
25
[BACKGROUND] The purpose of this study was to compare safety and efficacy outcomes between immediate breast reconstruction (IBR) and mastectomy alone in locally advanced breast cancer patients. [METHODS] We conducted a comprehensive literature search of PUBMED, EMBASE, and Cochrane databases. The primary outcomes evalu...
Immediate breast reconstruction; Locally advanced breast cancer; Meta-analysis; Overall survival; Surgical complication
0.782
82
Surgery; Oncology
Medicine
2,024
38,918,693
Does a high threshold of sensory responsiveness affect the development of pretend play in children on the autism spectrum?
Journal of neurodevelopmental disorders
J Neurodev Disord
16
1
10.1186/s11689-024-09551-y
eng
2,024
6
25
2,024
6
25
[BACKGROUND] Among the current avenues of research into the origins and development of the autism spectrum, those concerning atypical levels of sensory responsiveness are gaining increasing relevance. Researchers note the relationship of sensory responsiveness in children on the autism spectrum to their motor, cognitiv...
Autism spectrum; Level of sensory responsiveness; Pretend play
1.296
64
Cognitive Neuroscience; Neurology; Pathology and Forensic Medicine; Pediatrics, Perinatology and Child Health
Medicine; Neuroscience
2,024
38,918,668
Morphological Changes and Inflammation Preceded the Pathogenesis of 1,2-Dimethylhydrazine-Induced Colorectal Cancer.
Asian Pacific journal of cancer prevention : APJCP
Asian Pac J Cancer Prev
25
6
10.31557/APJCP.2024.25.6.2059
eng
2,024
6
1
2,024
6
1
[OBJECTIVE] This study examined the morphological changes in the colonic mucosa and the presence of inflammation in rats induced with 1,2-dimethylhydrazine (DMH) 30 mg/kg BW over 9, 11, and 13 weeks without a latency period. [METHODS] Hematoxylin and eosin staining was performed to assess the morphology and characteris...
CRC; Cyclooxygenase-2; aberrant crypt foci; dimethylhydrazine; tumor necrosis factor-
0.53
98
Public Health, Environmental and Occupational Health; Epidemiology; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,918,272
Point-of-care ultrasonography in Ukraine: a survey of anesthesiologists-intensivists participating in ultrasonography courses.
Canadian journal of anaesthesia = Journal canadien d'anesthesie
Can J Anaesth
71
10
10.1007/s12630-024-02789-z
eng
2,024
10
null
2,024
6
25
[PURPOSE] Despite the potential value of point-of-care ultrasonography (POCUS) in resource-limited environments, it is not widely used in low- and middle-income countries compared with high-income countries. We sought to evaluate the current POCUS practice of Ukrainian anesthesiologists who attended POCUS courses to gu...
Ukraine; anesthesiology; critical care; point-of-care ultrasonography (POCUS); practice standardization; survey
null
null
null
null
null
38,918,090
Evaluating the Prevalence of Cardiac Surgery-associated Acute Kidney Injury After Septal Myectomy Combined With Concomitant Procedures in Obstructive Hypertrophic Cardiomyopathy.
Journal of cardiothoracic and vascular anesthesia
J Cardiothorac Vasc Anesth
38
10
10.1053/j.jvca.2024.05.038
eng
2,024
10
null
2,024
5
31
[OBJECTIVES] Hypertrophic obstructive cardiomyopathy (HOCM) may be treated by septal myectomy. Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication, but little is known about its incidence after septal myectomy. The objectives of this work were to evaluate the prevalence of CSA-AKI after se...
acute kidney injury; beta-blockers; cardiac surgery; hypertrophic cardiomyopathy; myectomy; perioperative risk
0.68
100
Anesthesiology and Pain Medicine; Cardiology and Cardiovascular Medicine
Medicine
2,024
38,917,695
Insights from European Reference Network for rare neurological disorders study surveys on diagnosis, treatment, and management of NKX2-1-related disorders.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
Eur J Paediatr Neurol
51
null
10.1016/j.ejpn.2024.06.007
eng
2,024
7
null
2,024
6
19
[BACKGROUND] NKX2-1-related disorder (NKX2-1-RD) is a rare disease characterized by a triad of primary hypothyroidism, neonatal respiratory distress, and neurological features, including chorea. [OBJECTIVE] This study aimed to identify discrepancies in the management of NKX2-1-RD among European Union (EU) specialists. ...
Chorea; NKX2-1
0.836
79
Pediatrics, Perinatology and Child Health; Medicine; Neurology
Medicine
2,024
38,916,821
Outcomes of older adults with early-stage triple-negative breast cancer (TNBC) receiving chemotherapy: a single-institution experience.
Breast cancer research and treatment
Breast Cancer Res Treat
207
1
10.1007/s10549-024-07309-7
eng
2,024
8
null
2,024
6
25
[BACKGROUND] Despite lower chemotherapy use in older triple-negative breast cancer (TNBC) patients, their outcomes match younger counterparts. We compared outcomes in early-stage TNBC patients by age receiving chemotherapy at a major cancer center with a national TNBC database. [METHODS] Retrospective study using insti...
Anthracycline; Breast cancer; Chemotherapy; Older adults; Stage; Triple-negative breast cancer
1.351
184
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,916,216
The Role of Routine Pathologic Assessment After Pediatric Osteochondroma Excision.
Journal of pediatric orthopedics
J Pediatr Orthop
44
8
10.1097/BPO.0000000000002750
eng
2,024
9
1
2,024
6
21
[BACKGROUND] Osteochondromas are benign osseous lesions often excised for pain, growth abnormalities, and aesthetic concerns. While characteristic clinical and radiographic features leave little diagnostic ambiguity in most cases of osteochondroma, pathologic analysis to confirm the diagnosis and screen for malignancy ...
null
null
null
null
null
null
38,915,465
Intravenous thrombolysis versus dual antiplatelet therapy for patients with acute minor ischaemic stroke: a systematic review and meta-analysis.
Frontiers in pharmacology
Front Pharmacol
15
null
10.3389/fphar.2024.1377475
eng
2,024
null
null
2,024
6
10
[BACKGROUND AND PURPOSE] The efficacy of intravenous thrombolysis (IVT) in patients with acute minor ischaemic stroke (AMIS) remains unclear. We performed a meta-analysis to compare the efficacy and safety of IVT and dual antiplatelet therapy (DAPT) in patients with AMIS. [METHODS] The Embase, Cochrane Library, PubMed,...
acute ischaemic stroke; dual antiplatelet therapy; intravenous thrombolysis; meta-analysis; minor stroke
1.22
175
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,915,400
Healthcare resource utilization patterns in psoriasis patients using biologic and conventional treatments in Finland.
Frontiers in immunology
Front Immunol
15
null
10.3389/fimmu.2024.1374829
eng
2,024
null
null
2,024
6
10
[INTRODUCTION AND AIM] Psoriasis vulgaris is associated with a significant healthcare burden, which increases over time as the disease progresses. The aim of this retrospective, population-based registry study was to characterize healthcare resource utilization (HCRU) in patients with psoriasis using biologics and oral...
Psoriasis vulgaris; biologic; biological treatment; healthcare resource utilization; oral immunosuppressants; real-world evidence
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
38,915,206
UBE2S promotes glycolysis in hepatocellular carcinoma by enhancing E3 enzyme-independent polyubiquitination of VHL.
Clinical and molecular hepatology
Clin Mol Hepatol
30
4
10.3350/cmh.2024.0236
eng
2,024
10
null
2,024
6
25
[BACKGROUND/AIMS] Ubiquitination is widely involved in the progression of hepatocellular carcinoma (HCC) by regulating various cellular processes. However, systematic strategies for screening core ubiquitin-related genes, clarifying their functions and mechanisms, and ultimately developing potential therapeutics for pa...
Glycolysis; Hepatocellular carcinoma; Ube2S protein, human; Ubiquitination; VHL protein, human
3.635
65
Hepatology; Medicine; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,915,067
Occurrence of pendelluft during ventilator weaning with T piece correlated with increased mortality in difficult-to-wean patients.
Journal of intensive care
J Intensive Care
12
1
10.1186/s40560-024-00737-z
eng
2,024
6
24
2,024
6
24
[BACKGROUND] Difficult-to-wean patients, typically identified as those failing the initial spontaneous breathing trial (SBT), face elevated mortality rates. Pendelluft, frequently observed in patients experiencing SBT failure, can be conveniently detected through bedside monitoring with electrical impedance tomography ...
Difficult-to-wean; Electrical impedance tomography; Mortality; Pendelluft
1.286
59
Critical Care and Intensive Care Medicine
Medicine
2,024
38,914,997
Sex dimorphism of IL-17-secreting peripheral blood mononuclear cells in ankylosing spondylitis based on bioinformatics analysis and machine learning.
BMC musculoskeletal disorders
BMC Musculoskelet Disord
25
1
10.1186/s12891-024-07589-6
eng
2,024
6
24
2,024
6
24
[BACKGROUND] Ankylosing spondylitis (AS) with radiographic damage is more prevalent in men than in women. IL-17, which is mainly secreted from peripheral blood mononuclear cells (PBMCs), plays an important role in the development of AS. Its expression is different between male and female. However, it is still unclear w...
Ankylosing spondylitis; Bioinformatics analysis; Interleukin-17; Machine learning; Sex dimorphism
0.805
131
Orthopedics and Sports Medicine; Rheumatology
Medicine
2,024
38,914,876
Efficacy and Safety of Trazodone and Gabapentin Fixed-Dose Combination in Patients Affected by Painful Diabetic Neuropathy: Randomized, Controlled, Dose-Finding Study.
Pain and therapy
Pain Ther
13
4
10.1007/s40122-024-00624-3
eng
2,024
8
null
2,024
6
24
[INTRODUCTION] Up to 50% of diabetic patients with neuropathy suffer from chronic pain, namely painful diabetic neuropathy (PDN), an unmet medical need with significant impact on quality of life. Gabapentin is widely used for PDN, albeit with frequent dose-limiting effects. Trazodone, an antidepressant with multi-modal...
Painful diabetic neuropathy; Trazodone
1.034
41
Anesthesiology and Pain Medicine; Neurology
Medicine
2,024
38,914,871
Aphakia treatment with sutureless scleral fixation or retropupillary iris-claw intraocular lens implantation: visual acuity, anterior segment and keratometry outcomes.
International ophthalmology
Int Ophthalmol
44
1
10.1007/s10792-024-03187-6
eng
2,024
6
24
2,024
6
24
[PURPOSE] Evaluation of anterior segment parameters using the Scheimpflug corneal topography 1 year after surgery in patients who underwent sutureless scleral fixation intraocular lens (SFIOL) implantation using the modified Yamane technique and retropupillary iris-claw intraocular lens (RPIOL) implantation. [METHODS] ...
Anterior segment structures; Aphakia; Iris claw; Modified Yamane technique; Scheimpflug corneal topography; Sutureless scleral fixation
0.642
57
Ophthalmology
Medicine
2,024
38,914,446
Implementation of an ISO 15189 accredited next generation sequencing service for cell-free total nucleic acid (cfTNA) analysis to facilitate driver mutation reporting in blood: the experience of a clinical diagnostic laboratory.
Journal of clinical pathology
J Clin Pathol
null
null
10.1136/jcp-2024-209514
eng
2,024
8
7
2,024
8
7
[AIMS] Next generation sequencing (NGS) on tumour tissue is integral to the delivery of personalised medicine and targeted therapy. NGS on liquid biopsy, a much less invasive technology, is an emerging clinical tool that has rapidly expanded clinical utility. Gene mutations in cell-free total nucleic acids (cfTNA) circ...
DIAGNOSIS; DNA; Pathology, Molecular
0.802
158
Pathology and Forensic Medicine; Medicine
Medicine
2,024
38,913,799
Cervical Dissection in Patients With Tandem Lesions Is Associated With Distal Embolism and Lower Recanalization Success.
Stroke
Stroke
55
7
10.1161/STROKEAHA.123.046148
eng
2,024
7
null
2,024
6
24
[BACKGROUND] Tandem lesions consist of cervical internal carotid artery (ICA) stenosis or occlusion, most commonly of atherosclerosis or dissection etiology, plus a large vessel occlusion. In this study, we compare outcomes in patients with atherosclerosis versus dissection of the cervical ICA. [METHODS] This multicent...
atherosclerosis; carotid artery, internal; dissection; ischemic stroke; thrombectomy
2.659
370
Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience
Medicine; Neuroscience; Nursing
2,024
38,913,796
Re-Imagining Hospital Patient Room Design for People After stroke: A Randomized Controlled Study Using Virtual Reality.
Stroke
Stroke
55
7
10.1161/STROKEAHA.124.046252
eng
2,024
7
null
2,024
6
24
[BACKGROUND] The hospital's physical environment can impact health and well-being. Patients spend most of their time in their hospital rooms. However, little experimental evidence supports specific physical design variables in these rooms, particularly for people poststroke. The study aimed to explore the influence of ...
hospitals; research design; stroke; virtual reality
2.659
370
Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience
Medicine; Neuroscience; Nursing
2,024
38,913,440
Stellate ganglion block for visceral pain in elderly patients undergoing video-assisted thoracoscopic lung cancer surgery: a randomized, controlled trial.
International journal of surgery (London, England)
Int J Surg
110
11
10.1097/JS9.0000000000001867
eng
2,024
11
1
2,024
11
1
[BACKGROUND] Visceral pain occurs commonly following thoracic surgery, but an effective method to relieve visceral pain in thoracic surgery remains controversial. The authors test the effect of stellate ganglion blocks (SGB) on perioperative visceral pain following video-assisted thoracoscopic surgery (VATS). [METHODS]...
null
2.076
99
Medicine; Surgery
Medicine
2,024
38,913,436
Prognostic factors of extracorporeal shockwave therapy in the treatment of nonunion in long bones: a retrospective study.
International journal of surgery (London, England)
Int J Surg
110
10
10.1097/JS9.0000000000001848
eng
2,024
10
1
2,024
10
1
[BACKGROUND] Nonunion of long bone fractures is a significant complication following surgical fixation, with an incidence ranging from 5 to 10%. Surgical intervention is the standard treatment for nonunions, but it may come with potential complications. Nonoperative approaches, such as Extracorporeal Shockwave Therapy ...
null
2.076
99
Medicine; Surgery
Medicine
2,024
38,913,347
Seroprevalence of hepatitis A virus among people born before and after implementation of universal vaccination in Argentina.
Infectious diseases (London, England)
Infect Dis (Lond)
56
11
10.1080/23744235.2024.2370975
eng
2,024
11
null
2,024
6
24
[BACKGROUND] Until 2005, when a single dose of vaccine was implemented in one-year-old children, the Hepatitis A virus (HAV) was responsible for approximately 90% of acute hepatitis cases in the paediatric population in Argentina. However, despite vaccination success, sporadic outbreaks of HAV still occur among adults....
Hepatitis A virus; seroprevalence; single dose; universal vaccination
0.957
84
Immunology and Microbiology; Medicine; Infectious Diseases; Microbiology
Immunology and Microbiology; Medicine
2,024