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38,951,433
The OCT2/MATE1 Interaction Between Trifluridine, Metformin and Cimetidine: A Crossover Pharmacokinetic Study.
Clinical pharmacokinetics
Clin Pharmacokinet
63
7
10.1007/s40262-024-01390-3
eng
2,024
7
null
2,024
6
28
[BACKGROUND AND OBJECTIVES] Trifluridine/tipiracil, registered for the treatment of patients with metastatic gastric and colorectal cancer, is a substrate and inhibitor for the organic cation transporter 2 (OCT2) and the multidrug and toxin extrusion protein 1 (MATE1), which raises the potential for drug-drug interacti...
null
1.305
191
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,951,386
Cancer fatalism, social media informational awareness, and education.
Cancer causes control : CCC
Cancer Causes Control
35
10
10.1007/s10552-024-01896-y
eng
2,024
10
null
2,024
6
29
[OBJECTIVE] Understand if cancer fatalism among adult social media users in the United States is linked to social media informational awareness and if the relationship varies by education level. [METHODS] Cross-sectional data from the 2022 Health Information National Trends Survey (n = 3,948) were analyzed using multiv...
Cancer; Consumer health information; Cross-sectional study; Disinformation; Education; Health literacy; Misinformation; Social media; United States
null
null
null
null
null
38,951,359
Meiotic maturation failure in primary ovarian insufficiency: insights from a bovine model.
Journal of assisted reproduction and genetics
J Assist Reprod Genet
41
8
10.1007/s10815-024-03160-3
eng
2,024
8
null
2,024
6
29
[PURPOSE] Oocytes from women presenting primary ovarian insufficiency (POI) generate viable embryos at a lower rate than non-POI women, but the mechanisms responsible for the lower oocyte quality remain elusive. Due to the scarcity of human oocytes for research, animal models provide a promising way forward. We aimed a...
Bovine; Meiosis; Oocyte; Oocyte competence; Primary ovarian insufficiency; Transcriptome
0.868
101
Obstetrics and Gynecology; Developmental Biology; Genetics; Genetics; Medicine; Reproductive Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,950,951
Validation of Different Dementia Code-Based Definitions in a Population-Based Study of Rheumatoid Arthritis.
The Journal of rheumatology
J Rheumatol
51
10
10.3899/jrheum.2024-0299
eng
2,024
10
1
2,024
10
1
[OBJECTIVE] Rheumatoid arthritis (RA) has been associated with an elevated dementia risk. This study aimed to examine how different diagnostic dementia definitions perform in patients with RA compared to individuals without RA. [METHODS] The study population included 2050 individuals (1025 with RA) from a retrospective...
ICD-10; ICD-9; code-based; dementia; rheumatoid arthritis
1.135
201
Rheumatology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
38,950,407
Changes in Urine Drug Screen Sensitivity in Adolescent Opioid Presentations to the Emergency Department.
Pediatric emergency care
Pediatr Emerg Care
40
9
10.1097/PEC.0000000000003173
eng
2,024
9
1
2,024
7
1
[INTRODUCTION] Adolescent overdoses have been rising over the past decade. Emergency department (ED) visits for both acute overdoses and for adolescents in opioid withdrawal have risen post-COVID. Urine drug screens have poor utility in the ED but are routinely obtained for medical clearance and in the management of pa...
null
0.549
79
Emergency Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,024
38,950,071
Systemic Treatment With Cyclosporine A in Children With Severe Vernal Keratoconjunctivitis.
Cornea
Cornea
44
3
10.1097/ICO.0000000000003613
eng
2,025
3
1
2,024
6
27
[PURPOSE] To report our experience with systemic cyclosporine as a treatment for severe vernal keratoconjunctivitis (VKC) in pediatric patients who did not respond to previous treatments. [METHODS] We analyzed the medical records of 6 patients, aged 4 to 15 years, with severe VKC treated with systemic cyclosporine for ...
null
0.955
141
Ophthalmology
Medicine
2,024
38,949,821
COVID-19 Vaccination in the First Trimester and Major Structural Birth Defects Among Live Births.
JAMA pediatrics
JAMA Pediatr
178
8
10.1001/jamapediatrics.2024.1917
eng
2,024
8
1
null
null
null
[IMPORTANCE] COVID-19 vaccination is recommended throughout pregnancy to prevent pregnancy complications and adverse birth outcomes associated with COVID-19 disease. To date, data on birth defects after first-trimester vaccination are limited. [OBJECTIVE] To evaluate the associated risks for selected major structural b...
null
5.085
231
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,949,392
Predictive value of early-phase heart rate reduction for subsequent recovery of left ventricular systolic function in heart failure with reduced ejection fraction.
Cardiology journal
Cardiol J
31
4
10.5603/cj.97021
eng
2,024
null
null
2,024
7
1
[INTRODUCTION] Predictors of heart failure with recovered ejection fraction (HFrecEF) remain to be fully elucidated. This study investigated the impact of heart rate and its change on the recovery of left ventricular ejection fraction (LVEF) in heart failure with reduced ejection fraction (HFrEF). [MATERIAL AND METHODS...
ejection fraction; heart failure; heart rate; improvement
0.613
47
Cardiology and Cardiovascular Medicine; Medicine
Medicine
2,024
38,949,175
Virtual reality-based therapy for chronic low back and neck pain: a systematic review with meta-analysis.
EFORT open reviews
EFORT Open Rev
9
7
10.1530/EOR-23-0197
eng
2,024
7
1
2,024
7
1
[PURPOSE] To compile all the scientific evidence available to date to evaluate the effect of virtual reality based therapy (VRBT) on reducing pain intensity, kinesiophobia, and associated disability, and on increasing the hr-QoL in patients with chronic neck pain (CNP) or chronic low back pain (CLBP). [METHODS] Studies...
chronic low back pain; chronic neck pain; disability; health related-quality of life; kinesiophobia; virtual reality-based therapy
1.776
57
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
38,949,152
NHANES 2011-2014: Objective Physical Activity Is the Strongest Predictor of All-Cause Mortality.
Medicine and science in sports and exercise
Med Sci Sports Exerc
56
10
10.1249/MSS.0000000000003497
eng
2,024
10
1
2,024
7
1
[INTRODUCTION] Objectively measured physical activity (PA) is a modifiable risk factor for mortality. Understanding the predictive performance of PA is essential to establish potential targets for early intervention to reduce mortality among older adults. [METHODS] The study used a subset of the National Health and Nut...
null
1.442
271
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,024
38,949,099
Hypophosphataemia and late-onset sepsis in extremely preterm neonates: A case-control study.
Journal of paediatrics and child health
J Paediatr Child Health
60
7
10.1111/jpc.16589
eng
2,024
7
null
2,024
7
1
[AIM] Late-onset sepsis (LOS) is common in extreme prematurity. These infants are at risk of refeeding syndrome-associated hypophosphataemia. Our objective was to investigate whether hypophosphataemia predisposes to LOS in extremely premature neonates. [METHODS] A retrospective case-control study of neonates born befor...
hyposphataemia; infection; neonate; parenteral nutrition; protein
0.536
90
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,948,978
Analysis of com plication s af te r out-of-ho sp i ta l cardiac a rr est of tar ge t temperat ure management.
JPMA. The Journal of the Pakistan Medical Association
J Pak Med Assoc
74
6
10.47391/JPMA.10129
eng
2,024
6
null
null
null
null
[OBJECTIVE] To analyse the preva lence of complications related to out-of-hospital cardiac arrest patients achieving target temperature management within 360 minutes compared to those taking more than 360 minutes. [METHODS] The retrospective study was conducted at a medical centre in Taiwan, and comprised data from Jan...
null
null
null
null
null
null
38,948,891
Heterogeneous body compositions and all-cause mortality in acute coronary syndrome patients: a ten-year retrospective cohort study.
Journal of geriatric cardiology : JGC
J Geriatr Cardiol
21
5
10.26599/1671-5411.2024.05.006
eng
2,024
5
28
null
null
null
[BACKGROUND] The association of different body components, including lean mass and body fat, with the risk of death in acute coronary syndrome (ACS) patients are unclear. [METHODS] We enrolled adults diagnosed with ACS at our center between January 2011 and December 2012 and obtained follow-up outcomes via telephone qu...
null
null
null
null
null
null
38,948,621
Hematological manifestation of Pediatric Systemic Lupus Erythematosus (SLE) - A single centered cross-sectional study.
Journal of family medicine and primary care
J Family Med Prim Care
13
5
10.4103/jfmpc.jfmpc_1583_23
eng
2,024
5
null
2,024
5
24
[INTRODUCTION] Systemic lupus erythematosus (SLE), the commonest type of lupus, is an autoimmune multisystemic disorder that can affect any organ system of the body, especially blood vessels and connective tissues, causing widespread inflammation. Pediatric onset of SLE is a rare condition with more hematological invol...
AIHA; Anemia; SLE; autoantibodies; hematological manifestations; leucopenia; lymphopenia; neutropenia; pediatric lupus; thrombocytopenia ds DNA
null
null
null
null
null
38,948,581
Safety monitoring of precautionary third dose of COVID-19 vaccines in a district in Northern India.
Journal of family medicine and primary care
J Family Med Prim Care
13
5
10.4103/jfmpc.jfmpc_973_23
eng
2,024
5
null
2,024
5
24
[BACKGROUND] The World Health Organization (WHO) declared Coronavirus disease-19 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) a pandemic on March 11, 2020. On 16[th] January 2021, India began its vaccination programme using two COVID-19 vaccines (Covishield and Covaxin). Precautiona...
COVID-19; Pharmacovigilance Programme of India (PvPI); precautionary dose (booster shots)
null
null
null
null
null
38,948,547
Utilization of adolescent-friendly health services and its determinants in a rural area of Maharashtra.
Journal of family medicine and primary care
J Family Med Prim Care
13
5
10.4103/jfmpc.jfmpc_1507_23
eng
2,024
5
null
2,024
5
24
[CONTEXT] Adolescent phase is a very crucial period in one's life, much emotional and psychological support is needed for an adolescent to bloom into a responsible adult. But unfortunately adolescents do not get the support or they fail to seek support due to lack of awareness. Government of India, to address this issu...
Adolescent friendly health clinics; adolescent friendly health services; late adolescents; rural area; utilization
null
null
null
null
null
38,948,202
Structured peer review: pilot results from 23 Elsevier journals.
PeerJ
PeerJ
12
null
10.7717/peerj.17514
eng
2,024
null
null
2,024
6
25
[BACKGROUND] Reviewers rarely comment on the same aspects of a manuscript, making it difficult to properly assess manuscripts' quality and the quality of the peer review process. The goal of this pilot study was to evaluate structured peer review implementation by: 1) exploring whether and how reviewers answered struct...
Academic journals; Inter-rater agreement; Peer review; Reviewers
0.625
124
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
38,948,086
The Impact of Air Pollution Controls on Health and Health Inequity Among Middle-Aged and Older Chinese: Evidence From Panel Data.
International journal of public health
Int J Public Health
69
null
10.3389/ijph.2024.1606956
eng
2,024
null
null
2,024
6
14
[OBJECTIVES] We evaluated the long-term effects of air pollution controls on health and health inequity among Chinese 45 years of age. [METHODS] Data were derived from the China Health Aging and Retirement Longitudinal Survey and the China National Environmental Monitoring Centre. Decreases in PM2.5 and PM10 were scale...
China; air pollution controls; difference-in-differences; health; health inequality
0.862
89
Health; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,024
38,947,373
Effectiveness and Determinants of Implementing the "Xinjiang Model" for Tuberculosis Prevention and Control: A Quantitative Study.
Infection and drug resistance
Infect Drug Resist
17
null
10.2147/IDR.S459228
eng
2,024
null
null
2,024
6
24
[OBJECTIVE] To analyze the effectiveness of the "Xinjiang Model" for tuberculosis prevention and control in Kashgar Prefecture, Xinjiang, and to explore the determinants of the policy implementation effect. [METHODS] The registration data of pulmonary tuberculosis (PTB) patients in Kashgar Prefecture from 2012 to 2021 ...
Xinjiang; determinants; implementation effect; pulmonary tuberculosis; registered incidence
0.793
74
Infectious Diseases; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,947,239
Causal relationship between type 1 diabetes mellitus and mycoses: a Mendelian randomization study.
Frontiers in medicine
Front Med (Lausanne)
11
null
10.3389/fmed.2024.1408297
eng
2,024
null
null
2,024
6
14
[BACKGROUND] Type 1 diabetes mellitus (T1DM) is frequently associated with various infections, including mycoses; however, the direct link between T1DM and fungal infections remains under-researched. This study utilizes a Mendelian randomization (MR) approach to investigate the potential causal relationship between T1D...
Mendelian randomization analysis; candidiasis; diabetes mellitus type 1; infections; mycoses
0.962
102
Medicine
Medicine
2,024
38,947,063
Exploring self-reported quality of life in developmental language disorder.
medRxiv : the preprint server for health sciences
medRxiv
null
null
10.1101/2024.06.19.24309096
eng
2,024
6
20
2,024
6
20
[PURPOSE] Developmental language disorder (DLD) is a lifelong condition associated with poorer outcomes than neurotypical peers, yet relatively little is known about long-term quality of life in DLD. This preliminary study adopts a neurodiversity-informed approach by exploring self-reported quality of life in an adoles...
null
null
null
null
null
null
38,946,989
Assessing the Risk of Heart Attack: A Bayesian Kernel Machine Regression Analysis of Heavy Metal Mixtures.
Research square
Res Sq
null
null
10.21203/rs.3.rs-4456611/v1
eng
2,024
6
18
2,024
6
18
[BACKGROUND] The assessment of heavy metals' effects on human health is frequently limited to investigating one metal or a group of related metals. The effect of heavy metals mixture on heart attack is unknown. [METHODS] This study applied the Bayesian kernel machine regression model (BKMR) to the 2011-2016 National He...
Bayesian kernel machine regression; Cardiovascular disease; Heart attack; Heavy metal mixtures; NHANES
null
null
null
null
null
38,946,924
Role and Results of Constrained Insert in Computer-Assisted Primary Total Knee Arthroplasty: A Propensity-Matched Study.
Arthroplasty today
Arthroplast Today
27
null
10.1016/j.artd.2024.101423
eng
2,024
6
null
2,024
6
5
[PURPOSE] Mild ligament imbalance is often encountered in the mediolateral plane during complex primary total knee arthroplasty. A constrained (CP) polyethylene insert compatible with the primary femur is useful to manage these cases without the need to fall back on revision implants. The aim of the study was to define...
Constrained insert; Mediolateral instability; Navigation; Total knee arthroplasty
0.918
32
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
38,946,855
Impact of index admission cholecystectomy vs interval cholecystectomy on readmission rate in acute cholangitis: National Readmission Database survey.
World journal of gastrointestinal endoscopy
World J Gastrointest Endosc
16
6
10.4253/wjge.v16.i6.350
eng
2,024
6
16
null
null
null
[BACKGROUND] Elective cholecystectomy (CCY) is recommended for patients with gallstone-related acute cholangitis (AC) following endoscopic decompression to prevent recurrent biliary events. However, the optimal timing and implications of CCY remain unclear. [AIM] To examine the impact of same-admission CCY compared to ...
30-d readmission rates; Acute cholangitis; Gallstone-related complications; In-hospital mortality; National Readmission Database; Resource utilization
null
null
null
null
null
38,946,753
Motivational Interviewing: Addressing Interest Among Health Professions Students.
PRiMER (Leawood, Kan.)
PRiMER
8
null
10.22454/PRiMER.2024.823357
eng
2,024
null
null
2,024
6
24
[BACKGROUND AND OBJECTIVES] Motivational interviewing (MI) is a patient-centered approach to behavior change counseling that is used among health professionals across multiple disciplines. However, MI training has yet to be broadly offered to health professional (HP) students. This study aimed to evaluate student inter...
null
null
null
null
null
null
38,946,752
Virtual Care Integration: Balancing Physician Well-Being.
PRiMER (Leawood, Kan.)
PRiMER
8
null
10.22454/PRiMER.2024.690812
eng
2,024
null
null
2,024
6
11
[BACKGROUND AND OBJECTIVES] According to self-determination theory (SDT), fulfillment of three basic psychological needs-autonomy, competence, and relatedness-positively impacts people's health and well-being. Amid the COVID-19 pandemic, an accelerated adoption of virtual care practices coincided with a decline in the ...
null
null
null
null
null
null
38,946,674
Clinical impacts of immunomodulator withdrawal from anti-tumor necrosis factor combination therapy in pediatric inflammatory bowel disease.
Journal of pediatric gastroenterology and nutrition
J Pediatr Gastroenterol Nutr
79
4
10.1002/jpn3.12299
eng
2,024
10
null
2,024
7
1
[OBJECTIVES] Combination therapy consists of both anti-tumor necrosis factor (anti-TNF) and an immunomodulator (IMM) and has been shown to improve outcomes in patients with inflammatory bowel disease (IBD). This study assesses the impacts of IMM withdrawal from combination therapy to anti-TNF monotherapy in children wi...
biologic; monotherapy; therapeutics
0.885
160
Pediatrics, Perinatology and Child Health; Gastroenterology
Medicine
2,024
38,946,513
Knowledge and awareness about temporomandibular disorder among dentists in India: Questionnaire study and review.
Journal of Indian Prosthodontic Society
J Indian Prosthodont Soc
24
3
10.4103/jips.jips_573_23
eng
2,024
7
1
2,024
7
1
[AIM] Temporomandibular disorders (TMD) comprise ailments involving the jaw joint (temporomandibular joint) and its associated anatomical structures. The complexity involved in TMD is primarily due to its broad spectrum of conditions, clinical signs and symptoms variability, and multifactorial etiology. Considering the...
null
0.41
35
Dentistry; Oral Surgery
Dentistry
2,024
38,946,508
Comparative evaluation of bond strength and color stability of polyetheretherketone and zirconia layered with indirect composite before and after thermocycling: An in vitro study.
Journal of Indian Prosthodontic Society
J Indian Prosthodont Soc
24
3
10.4103/jips.jips_36_24
eng
2,024
7
1
2,024
7
1
[AIM] This study investigates the interaction of zirconia and polyetheretherketone (PEEK) with indirect composite in fixed dental prostheses. This investigation aimed to assess the shear bond strength (SBS) and color stability of zirconia and PEEK before and after aging, addressing critical concerns in dental restorati...
null
0.41
35
Dentistry; Oral Surgery
Dentistry
2,024
38,946,138
Empagliflozin to prevent post-operative atrial fibrillation in patients undergoing coronary artery bypass graft surgery: Rationale and design of the EMPOAF trial.
Pacing and clinical electrophysiology : PACE
Pacing Clin Electrophysiol
47
8
10.1111/pace.15038
eng
2,024
8
null
2,024
6
30
[BACKGROUND] Postoperative atrial fibrillation (POAF) is one of the most common types of acute AF and can complicate the treatment course of approximately one third of patients undergoing cardiac surgery. Sodium-glucose cotransporter-2 (SGLT2) inhibitors are among the newest antidiabetic drugs which can be therapeutic ...
CABG; SGLT2 inhibitors; atrial fibrillation; cardiac surgery; empagliflozin
null
null
null
null
null
38,946,132
Sociodemographic precursors of explicit and implicit attitudes towards physical activity.
Psychology health
Psychol Health
null
null
10.1080/08870446.2024.2371964
eng
2,024
6
30
2,024
6
30
[OBJECTIVE] In high-income countries, people with low socio-economic status (SES) engage in less leisure-time physical activity (PA) than those with higher SES. Beyond a materialistic account of this difference, the role of motivational precursors-among which attitudes are emblematic-remains poorly understood, particul...
Socioeconomic; attitudes; health behaviors; health inequalities; implicit; physical activity; sociodemographic
null
null
null
null
null
38,945,735
Incidence and predictors of ipsilateral local recurrence following partial nephrectomy.
Urologic oncology
Urol Oncol
42
10
10.1016/j.urolonc.2024.05.004
eng
2,024
10
null
2,024
6
29
[PURPOSE] Ipsilateral local recurrence (LR) after partial nephrectomy (PN) for renal cell carcinoma (RCC) may result from a metachronous tumor or PN bed recurrence. To date, literature has predominantly reported ipsilateral LRs collectively, although the pathophysiology and prognostic implications of these event may be...
Local Recurrence; Partial Nephrectomy; Renal Cell Carcinoma
0.855
89
Urology; Oncology
Medicine
2,024
38,945,156
Is personal recovery a transdiagnostic concept? Testing the fit of the CHIME framework using narrative experiences.
Journal of mental health (Abingdon, England)
J Ment Health
34
3
10.1080/09638237.2024.2361225
eng
2,025
6
null
2,024
6
30
[BACKGROUND] Personal recovery is operationalized in the CHIME framework (connectedness, hope, identity, meaning in life, and empowerment) of recovery processes. CHIME was initially developed through analysis of experiences of people mainly with psychosis, but it might also be valid for investigating recovery in mood-r...
Autism; Recovery; psychosis; rehabilitation; severe mental illness; stories
1.212
88
Medicine; Psychiatry and Mental Health
Medicine
2,024
38,944,983
Testing the efficacy of a brief online writing intervention on body image and distress in female cancer survivors.
Patient education and counseling
Patient Educ Couns
127
null
10.1016/j.pec.2024.108356
eng
2,024
10
null
2,024
6
25
[OBJECTIVE] This study tested the feasibility and efficacy of two iterations of a low-intensity online writing intervention, Expand Your Horizon (EYH), in improving body image and distress in a cancer population. [METHODS] In study 1 (3-session version of EYH), adult female cancer survivors (N = 201) were randomised to...
Body functionality appreciation; Body image; Cancer survivors; Expressive writing; Females
1.237
168
Medicine
Medicine
2,024
38,944,693
The future of patient education: A study on AI-driven responses to urinary incontinence inquiries.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Int J Gynaecol Obstet
167
3
10.1002/ijgo.15751
eng
2,024
12
null
2,024
6
30
[OBJECTIVE] To evaluate the effectiveness of ChatGPT in providing insights into common urinary incontinence concerns within urogynecology. By analyzing the model's responses against established benchmarks of accuracy, completeness, and safety, the study aimed to quantify its usefulness for informing patients and aiding...
ChatGPT; Urogynecology; expert opinions; quality evaluation; urinary incontinence
null
null
null
null
null
38,944,581
Troubled but in good hands: A qualitative study on patient experiences in diuresis renography examinations.
Radiography (London, England : 1995)
Radiography (Lond)
30
5
10.1016/j.radi.2024.06.009
eng
2,024
8
null
2,024
6
28
[INTRODUCTION] Diuresis renography is a nuclear medicine examination that can distinguish between obstructive and non-obstructive uropathy. Renography has been investigated before, but not from a patient perspective. The aim of this study was to gain knowledge and understanding of patient experiences with the diuresis ...
Interview study; Patient experience; Qualitative study; Renography
0.654
43
Research and Theory; Assessment and Diagnosis; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine; Nursing
2,024
38,944,421
Expression of PD-L1 Is Increased by Methionine Restriction Using Recombinant Methioninase in Human Colorectal Cancer Cells.
Cancer genomics proteomics
Cancer Genomics Proteomics
21
4
10.21873/cgp.20457
eng
2,024
null
null
null
null
null
[BACKGROUND/AIM] It has been recently demonstrated that a methionine-restricted diet increases the response to immune checkpoint inhibitors (ICIs) via an increase in PD-L1 in a syngeneic mouse colorectal-cancer model. Our laboratory has developed recombinant methioninase (rMETase) to restrict methionine. The aim of the...
Colorectal cancer; PD-L1; immune checkpoints; methionine restriction; recombinant methioninase (rMETase)
null
null
null
null
null
38,944,322
Recovery of Full Hyperextension After Anterior Cruciate Ligament Reconstruction Is Associated With Better Functional Outcomes but Greater Anterior Cruciate Ligament-Related Laxity After a Minimum 24-Month Follow-Up.
Arthroscopy : the journal of arthroscopic related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Arthroscopy
41
5
10.1016/j.arthro.2024.06.015
eng
2,025
5
null
2,024
6
27
[PURPOSE] To evaluate patients who had anterior cruciate ligament (ACL) reconstruction with preoperative hyperextension and compare physical examination (KT-1000 and pivot shift) and patient-reported outcome measures of patients who recovered the entire hyperextension with patients who did not. [METHODS] Patients aged ...
null
null
null
null
null
null
38,943,943
Intrauterine gangrene of the right upper limb in a newborn baby: Case report.
International journal of surgery case reports
Int J Surg Case Rep
121
null
10.1016/j.ijscr.2024.109738
eng
2,024
8
null
2,024
5
8
[INTRODUCTION AND IMPORTANCE] Congenital gangrene of the limb in a newborn child is an extremely rare pathology with polyetiological causes that has not been fully studied. Therefore, each case of this pathology has its own characteristics of manifestations and allows you to get closer to solving this problem. [CASE PR...
Congenital gangrene; Limb amputation; Newborn; Thrombosis of the artery
0.238
31
Surgery
Medicine
2,024
38,943,935
Right side traumatic diaphragmatic hernia presented after 20 years with shortness of breath; a rare case presentation, and literature review.
International journal of surgery case reports
Int J Surg Case Rep
121
null
10.1016/j.ijscr.2024.109973
eng
2,024
8
null
2,024
6
27
[INTRODUCTION] A right side diaphragmatic injury was linked to serious trauma to the abdomen, pelvis, and chest. The most significant type of injury was blunt abdominal trauma sustained in a car collision. The left side was more likely than the right to experience herniation. The stomach and colon were the most often h...
Blunt injury; Case report; Delayed presentation; Diaphragmatic hernia; Surgical management
0.238
31
Surgery
Medicine
2,024
38,943,795
Area deprivation index and social vulnerability index in Milwaukee County: Impact on hospital outcomes after traumatic injuries.
Injury
Injury
55
8
10.1016/j.injury.2024.111693
eng
2,024
8
null
2,024
6
21
[BACKGROUND] Predisposing factors for traumatic injuries are complex and variable. Neighborhood environments may influence injury mechanism or outcomes. The Social Vulnerability Index (SVI) identifies areas at risk for emergencies; Area Deprivation Index (ADI) measures socioeconomic disadvantage. The objective was to a...
Deprivation; Mortality; Neighborhood; Outcomes; Social determinants of health; Socioeconomic status; Trauma, injury; Vulnerability
0.762
151
Emergency Medicine; Surgery; Orthopedics and Sports Medicine
Medicine
2,024
38,943,695
Chemotherapeutic potential of lupeol against cancer in pre-clinical model: A systematic review and meta-analysis.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Phytomedicine
132
null
10.1016/j.phymed.2024.155777
eng
2,024
9
null
2,024
5
31
[BACKGROUND] Extensive research on Lupeol's potential in cancer prevention highlights its ability to target various cancer-related factors. It regulates proliferative markers, modulates signaling pathways, including PI3K/AKT/mTOR, and influences inflammatory and apoptotic mechanisms. Additionally, Lupeol demonstrates s...
Chemosensitization; Chemotherapy; Lupeol; Meta-analysis; Systematic review; Tumor volume; Tumor weight
1.694
150
Complementary and Alternative Medicine; Drug Discovery; Molecular Medicine; Pharmaceutical Science; Pharmacology
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,943,202
Oral vaccination with a recombinant Lactobacillus plantarum expressing the Eimeria tenella rhoptry neck 2 protein elicits protective immunity in broiler chickens infected with Eimeria tenella.
Parasites vectors
Parasit Vectors
17
1
10.1186/s13071-024-06355-w
eng
2,024
6
28
2,024
6
28
[BACKGROUND] Chicken coccidiosis is a protozoan disease that leads to considerable economic losses in the poultry industry. Live oocyst vaccination is currently the most effective measure for the prevention of coccidiosis. However, it provides limited protection with several drawbacks, such as poor immunological protec...
Eimeria tenella; Lactobacillus plantarum; Dcpep; RON2; Vaccine
null
null
null
null
null
38,943,117
Deciphering the SOX4/MAPK1 regulatory axis: a phosphoproteomic insight into IQGAP1 phosphorylation and pancreatic Cancer progression.
Journal of translational medicine
J Transl Med
22
1
10.1186/s12967-024-05377-3
eng
2,024
6
28
2,024
6
28
[OBJECTIVE] This study aims to elucidate the functional role of IQGAP1 phosphorylation modification mediated by the SOX4/MAPK1 regulatory axis in developing pancreatic cancer through phosphoproteomics analysis. [METHODS] Proteomics and phosphoproteomics data of pancreatic cancer were obtained from the Clinical Proteomi...
IQGAP1 phosphorylation; KSEA analysis; MAPK1 kinase; Pancreatic cancer; Phosphoproteomics; SOX4; Tumor growth and metastasis; Tumor typing
1.997
153
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
38,943,111
Best predictive single nephrometry score component to correlate with achievement of trifecta outcome in laparoscopic and robotic surgery.
BMC urology
BMC Urol
24
1
10.1186/s12894-024-01518-4
eng
2,024
6
28
2,024
6
28
[BACKGROUND] To evaluate the predictive value of individual components of the R.E.N.A.L scoring system for Laparoscopic (LPN) and Robotic Partial Nephrectomy (RPN). [METHODS] Patients that had undergone a Laparoscopic (LPN) or Robotic Partial Nephrectomy (RPN) between 2018 and 2023 were reviewed. Our data collection in...
Laparoscopic partial nephrectomy; Nephrometry system; Renal cell carcinoma; Robotic partial nephrectomy; Trifecta outcomes
0.593
57
Medicine; Reproductive Medicine; Urology
Medicine
2,024
38,993,207
The Optimal Model for Copy-Move Forgery Detection in Medical Images.
Journal of medical signals and sensors
J Med Signals Sens
14
null
10.4103/jmss.jmss_35_22
eng
2,024
null
null
2,024
3
26
[BACKGROUND] Digital devices can easily forge medical images. Copy-move forgery detection (CMFD) in medical image has led to abuses in areas where access to advanced medical devices is unavailable. Forgery of the copy-move image directly affects the doctor's decision. The method discussed here is an optimal method for ...
Copy-move forgery detection; discrete cosine transform; discrete wavelet transform; equilibrium optimization; medical image
null
null
null
null
null
38,993,159
Comparing AVPU and Glasgow Coma Scales Among Children Seen by Emergency Medical Services.
Pediatrics
Pediatrics
154
2
10.1542/peds.2024-066168
eng
2,024
8
1
null
null
null
[OBJECTIVES] Consciousness assessment is an important component in the prehospital care of ill or injured children. Both the Glasgow Coma Scale (GCS) and the Alert, Verbal, Pain, Unresponsive (AVPU) scale are used for this purpose. We sought to identify cut points for the GCS to correspond to the AVPU scale for pediatr...
null
2.406
409
Pediatrics, Perinatology and Child Health
Medicine
2,024
38,993,150
An open-label, first-in-human, single agent, dose escalation study for the evaluation of safety and efficacy of SAR442085 in patients with relapsed or refractory multiple myeloma.
European journal of haematology
Eur J Haematol
113
5
10.1111/ejh.14270
eng
2,024
11
null
2,024
7
12
[OBJECTIVES] Cluster of differentiation 38 (CD38) is a key target on multiple myeloma (MM) cells. This multi-centre, Phase 1, single-agent study (NCT04000282) investigated SAR442085, a novel fragment crystallisable (Fc)-modified anti-CD38 monoclonal antibody (mAb), with enhanced affinity towards Fc-gamma receptor on ef...
daratumumab; isatuximab; multiple myeloma; relapsed/refractory
1
99
Hematology; Medicine
Medicine
2,024
38,992,956
Assessment of the piroxicam-incited model of synchronized colitis in T-cell receptor alpha chain-deficient mice.
Animal models and experimental medicine
Animal Model Exp Med
7
4
10.1002/ame2.12456
eng
2,024
8
null
2,024
7
11
[BACKGROUND] A multitude of mouse models are utilized to emulate and study intestinal inflammation. T-cell receptor alpha chain (TCRα)-deficient mice are used as a model of spontaneous colitis that has similarities with human ulcerative colitis. However, colitis is triggered late in the life of the mouse (age: 4-5 mont...
colon; dexamethasone; histology; induction; inflammation; knockout
1.167
33
Biochemistry; Medical Laboratory Technology; Medicine; Veterinary; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine; Veterinary
2,024
38,992,754
Organophosphate ester flame retardant chemicals and maternal depression during pregnancy.
Environmental research
Environ Res
259
null
10.1016/j.envres.2024.119581
eng
2,024
10
15
2,024
7
9
[BACKGROUND] Depression substantially contributes to pregnancy-related morbidity, and pregnancy is increasingly recognized as a vulnerable window for exposure effects on maternal mental health. Exposures to organophosphate esters (OPEs) are ubiquitous and may have neurotoxic effects; however, their impacts on prenatal ...
Maternal depression; Mixtures analysis; Organophosphate esters
1.822
196
Biochemistry; Environmental Science; Public Health, Environmental and Occupational Health
Biochemistry, Genetics and Molecular Biology; Environmental Science; Medicine
2,024
38,992,283
From FUSE to a hands-on electrosurgery course using a cadaveric model.
Surgical endoscopy
Surg Endosc
38
9
10.1007/s00464-024-11033-0
eng
2,024
9
null
2,024
7
11
[INTRODUCTION] Surgical procedures in contemporary practice frequently employ energy-based devices, yet comprehensive education surrounding their safety and effectiveness remains deficient. We propose an innovative course for residents that aims to provide basic electrosurgery knowledge and promote the safe use of thes...
Curriculum; Electrosurgery; Energy device; FUSE; Patient safety; Surgical education
1.023
178
Surgery
Medicine
2,024
38,992,238
Patient attitudes and experiences towards exercise during oncological treatment. A qualitative systematic review.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
32
8
10.1007/s00520-024-08649-2
eng
2,024
7
12
2,024
7
12
[PURPOSE] Exercise and physical activity (PA) during oncological treatment have many benefits. However, PA levels and adherence are often low. This systematic review of qualitative literature aims to explore the experience and the perceived barriers and facilitators to exercise and physical activity during treatment. [...
Cancer treatment; Experiences; Physical activity; Qualitative review
1.109
143
Oncology; Rehabilitation; Oncology
Medicine; Nursing
2,024
38,990,646
Exploring the anxiolytic mechanism of Fructus gardeniae based on metabolomics, network pharmacology, and molecular docking.
The Journal of pharmacy and pharmacology
J Pharm Pharmacol
76
10
10.1093/jpp/rgad102
eng
2,024
10
3
null
null
null
[OBJECTIVE] To explore the effect and anxiolytic mechanism of a natural remedy called Fructus gardeniae (FG). [METHODS] The elevated-plus maze (EPM) test was used to confirm the anxiolytic effect of FG. The potential and anxiolytic components, targets, and route processes of FG were investigated using the network pharm...
Fructus gardeniae; anxiety; molecular docking; network pharmacology; untargeted metabolomics
0.717
142
Pharmaceutical Science; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
38,990,578
Waterpipe Tobacco Smoking and Risk of Cancer Mortality.
JAMA oncology
JAMA Oncol
10
9
10.1001/jamaoncol.2024.1939
eng
2,024
9
1
null
null
null
[IMPORTANCE] There has been an increasing trend of using noncigarette products, including waterpipe tobacco (WTP), worldwide. While cigarette smoking is a well-established risk factor for numerous cancers, little is known about the association between WTP smoking and cancer mortality. [OBJECTIVE] To assess the associat...
null
null
null
null
null
null
38,990,571
Secondhand Nicotine Absorption From E-Cigarette Vapor vs Tobacco Smoke in Children.
JAMA network open
JAMA Netw Open
7
7
10.1001/jamanetworkopen.2024.21246
eng
2,024
7
1
2,024
7
1
[IMPORTANCE] With the prevalence of e-cigarette use (vaping) increasing worldwide, there are concerns about children's exposure to secondhand vapor. [OBJECTIVE] To compare nicotine absorption among children who are (1) exposed to secondhand tobacco smoke only or (2) exposed to secondhand vapor only with (3) those expos...
null
3.546
154
Medicine
Medicine
2,024
38,990,557
Long-Term Outcomes of Self-Fit vs Audiologist-Fit Hearing Aids.
JAMA otolaryngology-- head & neck surgery
JAMA Otolaryngol Head Neck Surg
150
9
10.1001/jamaoto.2024.1825
eng
2,024
9
1
null
null
null
[IMPORTANCE] With rising interest in over-the-counter (OTC) hearing aids as an alternative to traditional audiologist-fit devices, understanding their long-term efficacy is crucial. However, given the novelty of the US Food and Drug Administration category of OTC hearing aids, minimal evidence currently supports their ...
null
null
null
null
null
null
38,989,483
A comparative evaluation of the effect of eugenol exposure time on the bond strength of an etch-and-rinse and a self-etch adhesive to dentin: An in vitro study.
Journal of conservative dentistry and endodontics
J Conserv Dent Endod
27
6
10.4103/JCDE.JCDE_136_24
eng
2,024
6
null
2,024
6
6
[AIM] The study aimed to comparatively evaluate the effect of eugenol exposure time on the micro-shear bond strength (μ-SBS) of etch-and-rinse and a self-etch adhesive to dentin. [MATERIALS AND METHODS] One hundred and twelve teeth samples were prepared from bisectioning 56 freshly extracted human mandibular molars and...
Provisional restorations; resin composite; self-adhesive; shear bond strength; zinc oxide eugenol
0.66
48
Dentistry
Dentistry
2,024
38,989,444
Transcatheter arterial chemoembolization with tyrosine kinase inhibitor in the 12-year treatment of hepatic metastases from gastrointestinal stromal tumor: a case report.
Journal of gastrointestinal oncology
J Gastrointest Oncol
15
3
10.21037/jgo-24-403
eng
2,024
6
30
2,024
6
27
[BACKGROUND] Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the digestive tract, with surgery and tyrosine kinase inhibitor (TKI) therapy being its main treatment options. However, long-term use of TKIs may lead to drug resistance, which poses a challenge to the long-term survival of pati...
Gastrointestinal stromal tumor (GIST); case report; imatinib; ripretinib; transcatheter arterial chemoembolization (TACE)
0.687
60
Gastroenterology; Oncology
Medicine
2,024
38,989,439
Identification and validation of Cystatin A as a novel promising therapeutic target for gastric cancer.
Journal of gastrointestinal oncology
J Gastrointest Oncol
15
3
10.21037/jgo-23-941
eng
2,024
6
30
2,024
6
27
[BACKGROUND] The effect of pharmacological treatment of gastric cancer (GC) is limited, thus, it holds significant scientific importance to thoroughly investigate the molecular mechanisms underlying GC development and identify novel molecules capable of substantially extending patients' survival. This study utilized bi...
Cystatin A (CSTA); Gastric cancer (GC); prognosis; tumor microenvironment (TME)
0.687
60
Gastroenterology; Oncology
Medicine
2,024
38,989,411
A single arm phase 2 clinical trial of YIV-906 with neoadjuvant concurrent chemo-radiation therapy in patients with locally advanced rectal cancer.
Journal of gastrointestinal oncology
J Gastrointest Oncol
15
3
10.21037/jgo-24-23
eng
2,024
6
30
2,024
6
25
[BACKGROUND] Pre-operative chemoradiation for rectal cancer is often associated with severe gastrointestinal (GI) toxicity which can interrupt, delay, and/or lead to termination of treatment. In this study, we evaluated whether the addition of YIV-906, a novel herbal medicine proven to reduce GI toxicity associated wit...
Neoadjuvant; radiation; rectal cancer; toxicity
0.687
60
Gastroenterology; Oncology
Medicine
2,024
38,989,237
ARISCAT and LAS VEGAS risk scores for predicting postoperative pulmonary complications after cardiac surgery: a cohort study.
Annals of medicine and surgery (2012)
Ann Med Surg (Lond)
86
7
10.1097/MS9.0000000000002191
eng
2,024
7
null
2,024
5
20
[BACKGROUND] Postoperative pulmonary complications (PPCs) could lead to morbidity, mortality, and prolonged hospital stay. Different risk-scoring systems are used to predict the identification of patients at risk of developing PPCs. The diagnostic accuracies of the Assess Respiratory Risk in Surgical Patients in Catalo...
ARISCAT risk index score; LAS VEGAS risk score; diagnostic accuracy; open-heart surgery; postoperative pulmonary complications (PPC)
null
null
null
null
null
38,989,144
Mechanism of baicalein in treatment of castration-resistant prostate cancer based on network pharmacology and cell experiments.
Frontiers in pharmacology
Front Pharmacol
15
null
10.3389/fphar.2024.1397703
eng
2,024
null
null
2,024
6
26
[OBJECTIVE] Baicalein, one of the most abundant flavonoids found in Chinese herb Scutellaria baicalensis Georgi, exhibits pharmacological activities against various cancers. However, the precise pharmacological mechanism of baicalein in treating castration-resistant prostate cancer (CRPC) remains elusive. This study ai...
baicalein; castration-resistant prostate cancer; cell cycle; cell proliferation; network pharmacology
1.22
175
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,988,992
Projected pooling loss for red nucleus segmentation with soft topology constraints.
Journal of medical imaging (Bellingham, Wash.)
J Med Imaging (Bellingham)
11
4
10.1117/1.JMI.11.4.044002
eng
2,024
7
null
2,024
7
9
[PURPOSE] Deep learning is the standard for medical image segmentation. However, it may encounter difficulties when the training set is small. Also, it may generate anatomically aberrant segmentations. Anatomical knowledge can be potentially useful as a constraint in deep learning segmentation methods. We propose a los...
anatomical priors; connected components; deep learning; loss function; segmentation; topology
0.523
54
Radiology, Nuclear Medicine and Imaging
Medicine
2,024
38,988,431
Profile of gastroduodenal perforation patients admitted in a rural tertiary care hospital: An observational cross-sectional study.
Journal of the West African College of Surgeons
J West Afr Coll Surg
14
3
10.4103/jwas.jwas_140_23
eng
2,024
null
null
2,024
5
24
[BACKGROUND] Gastro-duodenal perforation is a common surgical emergency that remains a formidable health burden worldwide with significant morbidity and mortality. Ulcer disease remains the most common cause of gastro-duodenal perforation. Diagnosing the presence of H. pylori can help eradicate the infection from the c...
Gastroduodenal perforation; H. pylori; tertiary hospital
null
null
null
null
null
38,988,422
Attitude and concerns on antenatal pelvic floor exercises among pregnant women in Ibadan, Nigeria.
Journal of the West African College of Surgeons
J West Afr Coll Surg
14
3
10.4103/jwas.jwas_142_23
eng
2,024
null
null
2,024
5
24
[AIM] Several studies had investigated the importance and benefit of pelvic floor exercises (PFEs) to the pregnant women and their unborn babies, however, the concerns of antenatal women on the exercise have been sparsely investigated. This study examined the attitude and concerns of pregnant women towards engaging in ...
Antenatal; childbirth; exercise; foetus; pelvic floor; pregnancy
null
null
null
null
null
38,988,411
TB and poverty: the effect of rifampicin-resistant TB on household income.
IJTLD open
IJTLD Open
1
4
10.5588/ijtldopen.23.0607
eng
2,024
4
null
2,024
4
1
[SETTING] The Republic of Moldova, one of Europe's poorest countries, also bears one of the highest burdens of rifampicin-resistant TB (RR-TB). [OBJECTIVES] To trace the patients' journey through TB in terms of the relationship with poverty and assess its determinants. [DESIGN] This cross-sectional study used secondary...
RR-TB; Republic of Moldova; income; out-of-pocket payment; rifampicin-resistant tuberculosis
null
null
null
null
null
38,988,208
Use of Azithromycin Attributable to Acute SARS-CoV-2 Infection.
Pharmacoepidemiology and drug safety
Pharmacoepidemiol Drug Saf
33
7
10.1002/pds.5857
eng
2,024
7
null
null
null
null
[PURPOSE] In the early stages of the COVID-19 pandemic, preliminary results that later proved to be incorrect suggested the possible efficacy of anti-infective drugs such as azithromycin for the treatment of SARS-CoV-2 infection. These preliminary data may have influenced the prescription of azithromycin. However, no i...
ORCHESTRA project; attributable use; azithromycin; defined daily dose
1.022
113
Pharmacology; Epidemiology
Medicine
2,024
38,988,093
Stereophotometric facial changes in edentulous older adults after rehabilitation with complete dentures.
Gerodontology
Gerodontology
42
1
10.1111/ger.12774
eng
2,025
3
null
2,024
7
10
[OBJECTIVES] To evaluate the facial characteristics of edentulous older adults who underwent rehabilitation using complete dentures, and to compare them with dentate individuals. [BACKGROUND] Edentulism rehabilitation with complete dentures aims to restore occlusion and facial aesthetics. [MATERIALS AND METHODS] The st...
complete dentures; edentulism; facial characteristics; gerodontology; older adults; prosthodontic rehabilitation
0.796
69
Dentistry; Geriatrics and Gerontology
Dentistry; Medicine
2,024
38,987,990
The uneven impact of Medicaid expansion on rural and urban Black, Latino/a, and White mortality.
The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association
J Rural Health
41
1
10.1111/jrh.12859
eng
2,025
1
null
2,024
7
10
[PURPOSE] To determine the differential impact of Medicaid expansion on all-cause mortality between Black, Latino/a, and White populations in rural and urban areas, and assess how expansion impacted mortality disparities between these groups. [METHODS] We employ a county-level time-varying heterogenous treatment effect...
Medicaid; mortality; mortality disparities; race and ethnicity; rural
1.609
74
Public Health, Environmental and Occupational Health
Medicine
2,024
38,987,890
Effect of a peer-led emergency department behavioral intervention on non-fatal opioid overdose: 18-month outcome in the Navigator randomized controlled trial.
Addiction (Abingdon, England)
Addiction
119
12
10.1111/add.16581
eng
2,024
12
null
2,024
7
10
[BACKGROUND AND AIMS] Emergency departments (EDs) provide an opportunity to identify people at risk of overdose and reduce the risk. We evaluated the effect of an ED behavioral intervention delivered by peer recovery support specialists (PRSSs) on non-fatal opioid overdose. [DESIGN] Two-arm, randomized trial. [SETTING]...
behavioral intervention; drug overdose; opioid overdose; peer recovery specialist; social work; substance use
2.357
224
Medicine; Psychiatry and Mental Health
Medicine
2,024
38,987,838
Laryngeal cancer incidence trends in the United States over 2000-2020: a population-based analysis.
Archives of public health = Archives belges de sante publique
Arch Public Health
82
1
10.1186/s13690-024-01333-1
eng
2,024
7
10
2,024
7
10
[INTRODUCTION] Laryngeal cancers account for one-third of all head and neck cancers. We aimed to report the incidence trends of laryngeal cancer over 2000-2020 in the United States (US), by age, sex, race/ethnicity, and histological subtypes. [METHODS] Data from the Surveillance, Epidemiology, and End Results 22 databa...
Epidemiology; Head and Neck Cancer; Incidence; Laryngeal Cancer; SEER; Surveillance, epidemiology, and end results; United States
null
null
null
null
null
38,987,694
Association between different obesity patterns and the risk of NAFLD detected by transient elastography: a cross-sectional study.
BMC gastroenterology
BMC Gastroenterol
24
1
10.1186/s12876-024-03303-x
eng
2,024
7
10
2,024
7
10
[BACKGROUND] Obesity has become a major global public health challenge. Studies examining the associations between different obesity patterns and the risk of nonalcoholic fatty liver disease (NAFLD) are limited. This study aimed to investigate the relationships between different obesity patterns and the risk of NAFLD i...
Cross-sectional; Hepatic fibrosis; NAFLD; Obesity patterns; Transient elastography
0.844
99
Gastroenterology; Medicine
Medicine
2,024
38,987,101
Comparison of Propofol-Based Total Intravenous Anesthesia versus Volatile Anesthesia with Sevoflurane for Postoperative Delirium in Adult Coronary Artery Bypass Grafting Surgery: A Prospective Randomized Single-Blinded Study.
Journal of cardiothoracic and vascular anesthesia
J Cardiothorac Vasc Anesth
38
9
10.1053/j.jvca.2024.05.027
eng
2,024
9
null
2,024
5
23
[OBJECTIVES] To compare the incidence of delirium and early (at 1 week) postoperative cognitive dysfunction (POCD) between propofol-based total intravenous anesthesia (TIVA) and volatile anesthesia with sevoflurane in adult patients undergoing elective coronary artery bypass graft surgery (CABG) with cardiopulmonary by...
cardiopulmonary bypass; delirium; postoperative cognitive dysfunction; propofol; sevoflurane; total intravenous anesthesia
0.68
100
Anesthesiology and Pain Medicine; Cardiology and Cardiovascular Medicine
Medicine
2,024
38,986,486
Clinical Characteristics of Necrotizing Enterocolitis Diagnosed by Independent Adjudication of Abdominal Radiographs, Laparotomy, or Autopsy in Preterm Infants in the "Connection Trial".
American journal of perinatology
Am J Perinatol
42
2
10.1055/s-0044-1788275
eng
2,025
1
null
2,024
7
10
[OBJECTIVE] Necrotizing enterocolitis (NEC) classically is diagnosed by radiographic demonstration of pneumatosis intestinalis/portal venous gas (PI/PVG). This study examines clinical characteristics of NEC confirmed by independent evaluation of abdominal radiographs, taken for clinical signs of NEC, or by pathologic f...
null
0.713
87
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,024
38,985,502
Investigating the Use of Serious Games for Cancer Control Among Children and Adolescents: Scoping Review.
JMIR serious games
JMIR Serious Games
12
null
10.2196/58724
eng
2,024
7
10
2,024
7
10
[BACKGROUND] Effective health care services that meet the diverse needs of children and adolescents with cancer are required to alleviate their physical, psychological, and social challenges and improve their quality of life. Previous studies showed that serious games help promote people's health. However, the potentia...
adolescent; adolescents; cancer; cancer control; child; children; game; games; gaming; oncology; paediatric; paediatrics; pediatric; pediatrics; review methodology; review methods; scoping; scoping review; search; searches; searching; serious games; synthesis; teen; teenager; teenagers; teens; youth
1.144
45
Biomedical Engineering; Physical Therapy, Sports Therapy and Rehabilitation; Psychiatry and Mental Health; Rehabilitation
Engineering; Health Professions; Medicine
2,024
38,985,476
Mobile Media Content Exposure and Toddlers' Responses to Attention Prompts and Behavioral Requests.
JAMA network open
JAMA Netw Open
7
7
10.1001/jamanetworkopen.2024.18492
eng
2,024
7
1
2,024
7
1
[IMPORTANCE] With personalized touch-screen tablets, young children can choose content and engage in play-like activities. However, tablets may also reduce shared engagement as the action of viewing or touching the screen is often not visible to nearby adults. This may impact communicative gazing and pointing, which is...
null
3.546
154
Medicine
Medicine
2,024
38,985,441
Prevalence of Anal Human Papillomavirus Infection and Anal High-Grade Squamous Intraepithelial Lesions Among Men Who Have Sex With Men 50 Years and Older Living With or Without HIV.
Journal of acquired immune deficiency syndromes (1999)
J Acquir Immune Defic Syndr
96
5
10.1097/QAI.0000000000003450
eng
2,024
8
15
null
null
null
[BACKGROUND] Anal cancer is caused by human papillomavirus (HPV), particularly HPV-16, and is preceded by anal high-grade squamous intraepithelial lesions (HSILs). The incidence of anal cancer is highest among men who have sex with men (MSM) living with HIV (MSMLWH) and increases with age. However, most previous studie...
null
1.04
176
Infectious Diseases; Pharmacology
Medicine
2,024
38,985,170
Global, regional, and national burdens of atopic dermatitis under 14: a trend analysis and future prediction based on the global burden of disease study 2019.
Archives of dermatological research
Arch Dermatol Res
316
7
10.1007/s00403-024-03195-7
eng
2,024
7
10
2,024
7
10
[OBJECTIVE] The aim is to evaluate the global, regional, and national trends in the burden of children and adolescents under 14 from 1990 to 2019, as well as future trend predictions. [METHODS] In Global Burden of Disease (GBD), we reported the incidence, prevalence rate and the years lived with disability (YLDs), the ...
Atopic dermatitis; Average annual percentage change; Bayesian age-period-cohort; Global Burden of Disease; Predictions; Social development index; Trends
null
null
null
null
null
38,985,107
Investigation of efficacy of erector spinae plane block administered in different volumes on intraoperative opioid consumption and postoperative analgesia in breast surgery: Randomized, prospective, double-blind study.
Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology
Agri
36
3
10.14744/agri.2023.82346
eng
2,024
7
null
null
null
null
[OBJECTIVES] We investigated the efficacy of the erector spinae plane block, which has been proven to be effective in breast surgery, on intraoperative opioid consumption and postoperative analgesia when administered in different volumes with the same concentration of local anesthetic. [METHODS] This study is designed ...
null
null
null
null
null
null
38,985,035
Indications and outcomes of liver retransplantation in three medical centers.
Revista do Colegio Brasileiro de Cirurgioes
Rev Col Bras Cir
51
null
10.1590/0100-6991e-20243689-en
eng
2,024
null
null
2,024
7
5
[INTRODUCTION] retransplantation is the only viable treatment for patients with irreversible graft loss. The objective of this study was to analyze the indications and outcomes of liver retransplantation in three medical centers. [METHODS] a total of 66 patients who underwent liver retransplantation from September 1991...
null
null
null
null
null
null
38,984,814
The influence of previous preterm birth with singleton pregnancy on the risk of recurrence in subsequent twin pregnancy: a meta-analysis.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
J Obstet Gynaecol
44
1
10.1080/01443615.2024.2368769
eng
2,024
12
null
2,024
7
10
[BACKGROUND] Preterm birth is a significant obstetrical concern around the globe. With this study, we aimed to determine whether a prior singleton pregnancy preterm birth increases the likelihood of preterm birth in subsequent twin pregnancies. We designed his systematic review to provide valuable information for pregn...
Preterm birth; predictors of prematurity; twin gestation
0.459
61
Obstetrics and Gynecology
Medicine
2,024
38,984,083
Hydroxychloroquine-azithromycin, doubase C, and QTc prolongation in congolese patients with COVID-19: Myth or reality?
World journal of virology
World J Virol
13
2
10.5501/wjv.v13.i2.90668
eng
2,024
6
25
null
null
null
[BACKGROUND] QTc interval prolongation with an increased risk of torsade de pointes (Tsd) has been described in coronavirus disease 2019 (COVID-19) patients treated with hydroxychloroquine (HCQ) and azithromycin (AZI) in Western countries. In the DR Congo, few studies have evaluated the safety of this association or pr...
COVID-19; Doubase C; HCQ-AZT; QTc prolongation; Sub-Saharan Africa
null
null
null
null
null
38,983,666
Minimum 10-year follow-up outcomes of arthroscopic Bankart's repair with metallic anchors: Reliable results with low redislocation rates.
World journal of methodology
World J Methodol
14
2
10.5662/wjm.v14.i2.90280
eng
2,024
6
20
2,024
6
20
[BACKGROUND] With stiff competition from alternative albeit more expensive counterparts, it has become important to establish the applicability of metallic anchors for shoulder instability in the modern era. This can be accomplished, in part, by analysing long-term outcomes. [AIM] To analyse minimum 10-year outcomes fr...
Arthroscopic Bankart repair; Long-term outcomes; Low failure rates; Metallic anchors
null
null
null
null
null
38,983,365
Effects of vaccination against COVID-19 on overactive bladder symptoms on young population.
Frontiers in medicine
Front Med (Lausanne)
11
null
10.3389/fmed.2024.1338317
eng
2,024
null
null
2,024
6
25
[INTRODUCTION] The vaccines developed against COVID-19 have different modes of action, with a primary focus on the spike protein of the virus. Adverse effects following vaccination have been reported, including local and systemic symptoms. Understanding the potential side effects on the urinary tract after vaccination ...
COVID-19; OABSS; lower urinary tract; overactive bladder; vaccinations
0.962
102
Medicine
Medicine
2,024
38,983,183
Risk factor analysis and nomogram prediction model construction of postoperative complications of thoracoscopic non-small cell lung cancer.
Journal of thoracic disease
J Thorac Dis
16
6
10.21037/jtd-24-113
eng
2,024
6
30
2,024
6
12
[BACKGROUND] A series of complications will inevitably occur after thoracoscopic pulmonary resection. How to avoid or reduce postoperative complications is an important research area in the perioperative treatment of thoracic surgery. This study analyzed the risk factors for thoracoscopic postoperative complications of...
Non-small cell lung cancer (NSCLC); complications; nomogram model; thoracoscope
0.624
95
Pulmonary and Respiratory Medicine
Medicine
2,024
38,983,157
Diagnostic utility of adding needle aspiration (using PeriView FLEX needle) to radial endobronchial ultrasound guide sheath transbronchial lung biopsy: a single center retrospective study.
Journal of thoracic disease
J Thorac Dis
16
6
10.21037/jtd-23-1598
eng
2,024
6
30
2,024
6
12
[BACKGROUND] Radial endobronchial ultrasound (rEBUS) guide sheath (GS) transbronchial lung biopsy (TBLB) improves the diagnostic yield of peripheral lung lesions (PLL). However, its diagnostic yield is approximately 60%. We aimed to evaluate the diagnostic utility of adding rEBUS GS transbronchial needle aspiration (TB...
Solitary pulmonary nodule; bronchoscopy; image-guided biopsy; ultrasonography
0.624
95
Pulmonary and Respiratory Medicine
Medicine
2,024
38,983,142
Clipless internal mammary artery harvesting for minimally invasive coronary artery bypass grafting using the shear-tip harmonic scalpel.
Journal of thoracic disease
J Thorac Dis
16
6
10.21037/jtd-23-1810
eng
2,024
6
30
2,024
6
13
[BACKGROUND] The internal mammary artery (IMA) is the most commonly used graft in coronary artery bypass grafting (CABG) because of its superior long-term patency rate. However, its small diameter poses challenges in handling, and any vascular damage that may occur during harvesting can significantly affect surgical ou...
Harmonic scalpel; clipless internal mammary harvesting; minimally invasive cardiac surgery
0.624
95
Pulmonary and Respiratory Medicine
Medicine
2,024
38,982,988
Epidemiology of potential drug- drug interactions in hospitalized patients with type 2 diabetes mellitus in China: a retrospective study.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
15
null
10.3389/fendo.2024.1387242
eng
2,024
null
null
2,024
6
25
[BACKGROUND] Combination therapy was associated with an increased risk of drug- drug interactions (DDIs) in patients with type 2 diabetes mellitus (T2DM). The present study aimed to investigate the epidemiology of potential DDIs (pDDIs), including potential chemical drug-drug interactions (pCDIs) and potential herb-dru...
discharge; drug-drug interactions; herb-drug interactions; hospitalized patients; type 2 diabetes mellitus
1.472
138
Endocrinology, Diabetes and Metabolism
Medicine
2,024
38,982,879
Associations of Cognitive Expectancies With Auditory Hallucinations and Hallucinatory-Like Experiences in Patients With Schizophrenia.
Schizophrenia bulletin
Schizophr Bull
51
3
10.1093/schbul/sbae115
eng
2,025
5
8
null
null
null
[BACKGROUND] Various neurocognitive models explore perceptual distortions and hallucinations in schizophrenia and the general population. A variant of predictive coding account suggests that strong priors, like cognitive expectancy, may influence perception. This study examines if stronger cognitive expectancies result...
auditory verbal hallucinations; predictive coding; psychosis; strong priors; top-down
2.138
228
Psychiatry and Mental Health
Medicine
2,024
38,982,783
Effect of the Cluster Nursing through Empowerment Education on Patients Undergoing Radical Prostatectomy: A Retrospective Study.
Archivos espanoles de urologia
Arch Esp Urol
77
5
10.56434/j.arch.esp.urol.20247705.74
eng
2,024
6
null
null
null
null
[BACKGROUND] Radical prostatectomy (RP) is a treatment method for prostate cancer (PCa). However, patients usually experience urinary incontinence and a reduction in quality of life after surgery. Seeking a nursing programme is necessary to improve the prognosis of patients undergoing RP. This study aims to explore the...
clinical governance; education; empowerment; patient care bundles; prostate
null
null
null
null
null
38,982,726
Laying train tracks en route: How institutional education leaders navigate complexity during mandated curriculum change.
Medical education
Med Educ
58
12
10.1111/medu.15464
eng
2,024
12
null
2,024
7
9
[INTRODUCTION] Institutional education leaders serve key roles in leading major curricular change within residency education, yet little is known about how they accomplish these goals on the ground. Change management principles have predominantly been developed and described in the hierarchical context of management sc...
null
1.439
171
Education; Medicine
Medicine; Social Sciences
2,024
38,982,656
Patient preferences for preventive migraine treatments among Canadian adults: A discrete choice experiment.
Headache
Headache
65
1
10.1111/head.14781
eng
2,025
1
null
2,024
7
9
[OBJECTIVE] To evaluate preferences for key attributes of injected or infused preventive migraine treatments and assess heterogeneity in preferences among Canadian participants with migraine. [BACKGROUND] Current treatment options for migraine prevention differ in their attributes, including mode of administration, eff...
Canada; discrete choice experiment; intravenous; migraine; migraine prevention; patient preference
1.426
146
Neurology; Neurology
Medicine; Neuroscience
2,024
38,982,468
Chrysin-loaded PEGylated liposomes protect against alloxan-induced diabetic neuropathy in rats: the interplay between endoplasmic reticulum stress and autophagy.
Biological research
Biol Res
57
1
10.1186/s40659-024-00521-1
eng
2,024
7
9
2,024
7
9
[BACKGROUND] Diabetic neuropathy (DN) is recognized as a significant complication arising from diabetes mellitus (DM). Pathogenesis of DN is accelerated by endoplasmic reticulum (ER) stress, which inhibits autophagy and contributes to disease progression. Autophagy is a highly conserved mechanism crucial in mitigating ...
Alloxan-induced diabetes; Autophagy; Chrysin PEGylated liposomes; Endoplasmic reticulum stress; Neuropathy
null
null
null
null
null
38,982,427
IPSC-NSCs-derived exosomal let-7b-5p improves motor function after spinal cord Injury by modulating microglial/macrophage pyroptosis.
Journal of nanobiotechnology
J Nanobiotechnology
22
1
10.1186/s12951-024-02697-w
eng
2,024
7
9
2,024
7
9
[BACKGROUND] Following spinal cord injury (SCI), the inflammatory storm initiated by microglia/macrophages poses a significant impediment to the recovery process. Exosomes play a crucial role in the transport of miRNAs, facilitating essential cellular communication through the transfer of genetic material. However, the...
Exosomes; Neuroinflammation; Pyroptosis; Spinal cord injury
2.282
125
Applied Microbiology and Biotechnology; Bioengineering; Biomedical Engineering; Medicine; Molecular Medicine; Nanoscience and Nanotechnology; Pharmaceutical Science
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Engineering; Immunology and Microbiology; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,981,829
Preoperative Nonselective Chest Computed Tomography Prior to Primary Cardiac Surgery Results in Meaningful Change to Surgical Management: Systematic Review and Pooled Prevalence Meta-Analysis.
Heart, lung circulation
Heart Lung Circ
33
9
10.1016/j.hlc.2024.04.302
eng
2,024
9
null
2,024
7
8
[BACKGROUND] Routine screening chest computed tomography (CT) prior to primary cardiac surgery is advocated by some surgeons due to the purported benefits of identifying significant aortic calcification that impacts ongoing management, such as performing anaortic off-pump surgery or adjusting cannulation strategy. Addi...
Cardiac surgery; Cerebrovascular accident; Computed tomography
null
null
null
null
null
38,980,911
Blastocystis colonization and associations with population parameters in Thai adults.
PLoS neglected tropical diseases
PLoS Negl Trop Dis
18
7
10.1371/journal.pntd.0012292
eng
2,024
7
null
2,024
7
9
[BACKGROUND] Blastocystis is a unicellular eukaryote commonly found in the intestinal tract of humans and other animals. The prevalence of Blastocystis has been investigated in both developed and developing countries, yet its occurrence and distribution in rural locations has been less studied. Herein, we aimed to exam...
null
1.37
172
Infectious Diseases; Pharmacology, Toxicology and Pharmaceutics; Public Health, Environmental and Occupational Health
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
38,980,587
Laparoscopic Extended Segmentectomy VIII Guided by Three-Dimensional Reconstruction and Hepatic Veins with a Cranio-Caudal Approach.
Annals of surgical oncology
Ann Surg Oncol
31
10
10.1245/s10434-024-15766-z
eng
2,024
10
null
2,024
7
9
[INTRODUCTION] Minimally invasive resection of segment VIII is a technically challenging procedure, made even more challenging when the resection is extended to segment IV and/or segment VII. Parenchymal-sparing resections are frequently used in the management of liver metastases but expose to the risk of R1 resection,...
null
1.152
210
Surgery; Oncology
Medicine
2,024
38,980,421
To scan or not to scan? A retrospective cohort study analysing the efficacy of routine post-operative CT after brain biopsy.
Acta neurochirurgica
Acta Neurochir (Wien)
166
1
10.1007/s00701-024-06180-1
eng
2,024
7
9
2,024
7
9
[PURPOSE] Postoperative management following elective cranial surgery, particularly after biopsy procedures, varies significantly across neurosurgical centres. Routine postoperative head CT scans, traditionally performed to detect complications such as intracranial bleeding or cerebral oedema, lack substantial evidence...
Brain Biopsy; CT scan; Neuro-oncology
0.736
112
Surgery; Neurology
Medicine
2,024
38,980,396
Limited impact of traumatic brain injury on the post-traumatic inflammatory cellular response.
European journal of trauma and emergency surgery : official publication of the European Trauma Society
Eur J Trauma Emerg Surg
50
6
10.1007/s00068-024-02574-z
eng
2,024
12
null
2,024
7
9
[PURPOSE] Trauma triggers a systemic inflammatory cellular response due to tissue damage, potentially leading to a secondary immune deficiency. Trauma severity is quantified by the Injury Severity Score (ISS). Severe Traumatic Brain Injury (TBI) is associated with high ISSs due to high lethality, despite limited tissue...
Infection; Inflammation; Injury; Neutrophil; Trauma; Traumatic brain injury
0.757
54
Emergency Medicine; Surgery; Critical Care and Intensive Care Medicine; Orthopedics and Sports Medicine
Medicine
2,024
38,979,481
The immunologic outcomes and adverse events of COVID-19 vaccine booster dose in immunosuppressed people: A systematic review.
Preventive medicine reports
Prev Med Rep
44
null
10.1016/j.pmedr.2024.102778
eng
2,024
8
null
2,024
5
31
[INTRODUCTION] This study examines the efficacy and safety of three COVID-19 booster vaccines including mRNA-based vaccines (BNT162b2 (BioNTech/Pfizer) and/or mRNA-1273 (Moderna)), Non-Replicating Viral-Vector vaccines (ChAdOx1 nCoV-19 vaccine (AstraZeneca) and/or Ad26. COV2.S (Johnson Johnson)), and Protein Subunit v...
Adverse events; Booster dose; COVID-19; Immunogenicity; Immunologic outcomes; SARS-CoV-2
1.008
60
Public Health, Environmental and Occupational Health; Health Informatics
Medicine
2,024