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39,882,606
Ultra-Early Hematoma Expansion Is Associated With Ongoing Hematoma Growth and Poor Functional Outcome.
Stroke
Stroke
56
4
10.1161/STROKEAHA.124.050131
eng
2,025
4
null
2,025
1
30
[BACKGROUND] There are limited data on ultra-early hematoma growth dynamics and their clinical impact in primary intracerebral hemorrhage (ICH). We aimed to estimate the incidence of hematoma expansion within the hyperacute period of ICH, describe hematoma dynamics over time, investigate the associations between ultra-...
blood pressure; cerebral hemorrhage; hematoma; tomography; tranexamic acid
2.659
370
Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience
Medicine; Neuroscience; Nursing
2,024
39,882,390
Evaluating the effectiveness of genicular radiofrequency ablation for chronic knee pain using the patient-reported outcomes measurement information system (PROMIS) global health-physical health domain: Results of a cross-sectional cohort study.
Interventional pain medicine
Interv Pain Med
4
1
10.1016/j.inpm.2024.100539
eng
2,025
3
null
2,025
1
9
[OBJECTIVE] Evaluate the effectiveness of genicular nerve radiofrequency ablation (GNRFA) for chronic knee pain using the Patient-Reported Outcomes Measurement Information System Global Health, Physical Health score (PROMIS-GH-PH). [METHODS] Patients who underwent GNRFA at a tertiary academic center were identified by ...
Genicular nerve; Knee osteoarthritis; Knee pain; Radiofrequency ablation
0.258
6
Anesthesiology and Pain Medicine
Medicine
2,024
39,882,362
Development and validation of an explainable machine learning prediction model of hemorrhagic transformation after intravenous thrombolysis in stroke.
Frontiers in neurology
Front Neurol
15
null
10.3389/fneur.2024.1446250
eng
2,024
null
null
2,025
1
15
[OBJECTIVE] To develop and validate an explainable machine learning (ML) model predicting the risk of hemorrhagic transformation (HT) after intravenous thrombolysis. [METHODS] We retrospectively enrolled patients who received intravenous tissue plasminogen activator (IV-tPA) thrombolysis within 4.5 h after symptom onse...
acute ischemic stroke; explainability; hemorrhagic transformation; intravenous thrombolysis; machine learning
0.993
118
Neurology; Neurology
Medicine; Neuroscience
2,024
39,882,304
Effects of vitamin D supplementation on the glycaemic indices, lipid profile and liver function tests in patients with cirrhosis: a double-blind randomised controlled trial.
BMJ nutrition, prevention health
BMJ Nutr Prev Health
7
2
10.1136/bmjnph-2024-000938
eng
2,024
null
null
2,024
8
30
[BACKGROUND] Liver cirrhosis is considered a progressive disease that can eventually result in death. Vitamin D deficiency is prevalent in patients with cirrhosis. Few studies have been conducted on the effect of vitamin D supplementation in patients with cirrhosis. [OBJECTIVES] The aim of this study was to identify th...
Nutritional treatment
null
null
null
null
null
39,882,242
Suppression of MCP-1, IFN-γ and IL-6 production of HNSCC ex vivo by pembrolizumab added to docetaxel and cisplatin (TP) exceeding those of TP alone is linked to improved survival.
Frontiers in immunology
Front Immunol
15
null
10.3389/fimmu.2024.1473897
eng
2,024
null
null
2,025
1
15
[BACKGROUND] Adding pembrolizumab, an anti-PD-1 antibody approved for treatment of head and neck squamous cell carcinoma (HNSCC) to neoadjuvant (induction-) chemotherapy utilizing docetaxel and cisplatin (TP) followed by radiotherapy may improve outcome in larynx organ-preservation (LOP) that is investigated in the Eur...
CCL2); biomarker research; monocyte chemoattractant protein 1 (MCP-1; neoadjuvant (induction) chemotherapy; predictive assay for chemoresponse-evaluation
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
39,882,040
Evaluation of Bacillus coagulans LMG S-31876 for immunomodulation and stress: a double-blind, placebo-controlled clinical trial.
Frontiers in nutrition
Front Nutr
11
null
10.3389/fnut.2024.1484499
eng
2,024
null
null
2,025
1
15
[OBJECTIVE] The study aimed to analyze the safety and effectiveness of the ProBC Plus (Bacillus coagulans LMG S-31876) supplement across various health parameters, including stress levels, immunoglobulin levels, biochemical parameters, and vital signs. [METHODS] A randomized, double-blind, placebo-controlled clinical t...
ProBC Plus (Bacillus coagulans LMG S-31876); clinical trials; health; immune system; placebo; stress
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
39,882,031
Return to work after proximal humeral fractures: a single center study comparing conservative versus operative treatment.
Orthopedic reviews
Orthop Rev (Pavia)
17
null
10.52965/001c.128106
eng
2,025
null
null
2,025
1
27
[BACKGROUND] Adequate treatment of proximal humeral fractures (PHF) is essential for restoring shoulder function and expediting return-to-work (RTW). This study aims to assess the impact of conservative and operative treatments on RTW and PHF recovery. [OBJECTIVE AND METHODS] In a retrospective case-control study, 858 ...
permissive weight bearing; proximal humeral fractures; questionnaires; return to work; treatment
null
null
null
null
null
39,881,572
High Rates of Probable Posttraumatic Stress Disorder in an Acute Psychiatric Women's Inpatient Unit: An Opportunity to Improve Diagnosis and Direct Critical Efforts.
Journal of trauma dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)
J Trauma Dissociation
26
2
10.1080/15299732.2024.2448427
eng
2,025
null
null
2,025
1
29
[PURPOSE] Trauma disorders are prevalent and confer high rates of psychiatric comorbidity and functional impairment. Women are more likely to be affected by trauma disorders; however, rates and symptom burden in women's inpatient psychiatric units remains understudied. We hypothesized the prevalence of probable posttra...
Psychiatry; inpatient; posttraumatic stress disorder; suicide
null
null
null
null
null
39,881,367
The kidney reabsorption-related magnesium depletion score is associated with cardiovascular disease and longitudinal mortality in diabetic kidney disease patients.
Diabetology metabolic syndrome
Diabetol Metab Syndr
17
1
10.1186/s13098-025-01598-8
eng
2,025
1
29
2,025
1
29
[BACKGROUND] The kidney reabsorption is essential for maintaining magnesium homeostasis. This study aims to explore the relationship between kidney reabsorption-related magnesium depletion score (MDS) and the occurrence of cardiovascular disease (CVD) and prognosis in diabetic disease kidney (DKD) patients. [METHODS] W...
CVD; DKD; MDS; Magnesium depletion score; Mortality
null
null
null
null
null
39,881,339
Circumstantial risk factors for death after intensive care unit-to-unit inter-hospital transfer-a Swedish registry study.
Scandinavian journal of trauma, resuscitation and emergency medicine
Scand J Trauma Resusc Emerg Med
33
1
10.1186/s13049-025-01325-2
eng
2,025
1
29
2,025
1
29
[BACKGROUND] Unit-to-unit transfer of critically ill patients infers hazards that may cause adverse events. Circumstantial factors associated with mortality after intensive care include days in the ICU, night-time or weekend discharge and capacity transfer as compared to other reasons for transfer. Distance travelled m...
Intensive care transport; Intensive care unit; Mortality; Patient transfer
0.891
73
Critical Care and Intensive Care Medicine; Emergency Medicine
Medicine
2,024
39,881,244
Langerhans cell histiocytosis in children: the value of ultrasound in diagnosis and follow-up.
BMC medical imaging
BMC Med Imaging
25
1
10.1186/s12880-025-01563-x
eng
2,025
1
29
2,025
1
29
[BACKGROUND] Langerhans cell histiocytosis (LCH) is a rare disease, most prevalent in children. Ultrasound is a noninvasive, cheap, and widely available technique. However, systematic elucidation of sonographic features of LCH and treatment related follow-up are relatively few, resulting in overall underestimation of t...
Children; Langerhans cell histiocytosis; Ultrasound
0.701
56
Radiology, Nuclear Medicine and Imaging
Medicine
2,024
39,881,224
An autopsy case with tubular obstruction by impacted swollen blebs due to ischemic acute kidney injury.
BMC nephrology
BMC Nephrol
26
1
10.1186/s12882-025-03949-z
eng
2,025
1
29
2,025
1
29
[BACKGROUND] Oliguric acute kidney injury (AKI) is one of the critical conditions which needs emergent treatment due to the lack of the capacity of excreting toxins and fluids, and plasma membrane bleb formation is considered as one of the characteristic morphologic alterations in ischemic AKI in both animal models and...
Acute kidney injury; Autopsy; Bleb formation; Epon section; Toluidine blue-stain; Tubular obstruction theory
0.805
83
Nephrology
Medicine
2,024
39,881,120
Engaging Patients in Discussions About Medication Deprescribing.
Journal of general internal medicine
J Gen Intern Med
40
8
10.1007/s11606-024-09346-w
eng
2,025
6
null
2,025
1
29
[BACKGROUND] Deprescribing, intentional medication discontinuation or dose reduction, can reduce potentially inappropriate medication use and medication-related harms. Engaging patients in deprescribing discussions may increase likelihood of deprescribing and promote shared decision-making. [OBJECTIVE] To examine the i...
deprescribing; patient education; patient engagement; polypharmacy; shared-decision making
1.992
224
Internal Medicine
Medicine
2,024
39,880,284
Alternative Autologous Vein Grafts versus Single-Segment Great Saphenous Vein in Lower Extremity Bypass Surgery-Single-Center Study.
Annals of vascular surgery
Ann Vasc Surg
114
null
10.1016/j.avsg.2025.01.027
eng
2,025
5
null
2,025
1
27
[BACKGROUND] Studies comparing alternative autologous vein grafts (AAVGs) to single-segment great saphenous vein (ssGSV) grafts report mixed results. The status of AAVG as first choice when ssGSV is unavailable is not unequivocal based on current evidence. Our study compares results between AAVG and ssGSV in lower extr...
null
0.707
87
Cardiology and Cardiovascular Medicine; Medicine; Surgery
Medicine
2,024
39,879,674
Preterm Neonates Exhibit a "Catch-Up" Pattern in Motor Development During the Neonatal Period: A Diffusion Tensor Imaging Study.
Pediatric neurology
Pediatr Neurol
164
null
10.1016/j.pediatrneurol.2025.01.001
eng
2,025
3
null
2,025
1
7
[BACKGROUND] Preterm infants are at high risk for subsequent neurodevelopmental disability. Early developmental characterization of brain and neurobehavioral function is critical for identifying high-risk infants. This study aimed to elucidate the early evolution of sensorimotor function in preterm neonates by explorin...
Diffusion tensor imaging; Neurobehavioral; Postnatal development; Preterm neonates; White matter
0.825
111
Pediatrics, Perinatology and Child Health; Neurology; Neurology; Developmental Neuroscience
Medicine; Neuroscience
2,024
39,879,413
Intracameral voriconazole for severe fungal keratitis: a case series.
Arquivos brasileiros de oftalmologia
Arq Bras Oftalmol
88
3
10.5935/0004-2749.2024-0207
eng
2,025
null
null
2,025
1
27
[PURPOSE] This study aimed to report the use, efficacy, and safety of intracameral voriconazole as an adjuvant treatment for deep fungal keratitis. [METHODS] This was a prospective case series of seven eyes with fungal keratitis with anterior chamber involvement or a corneal ulcer refractory to conventional topical tre...
null
0.384
37
Medicine; Ophthalmology
Medicine
2,024
39,879,393
Effects of Hydration and a Hyaluronic Acid-Containing Lozenge on Voice Parameters in Conjunction With a Vocal Loading Test.
Journal of speech, language, and hearing research : JSLHR
J Speech Lang Hear Res
68
2
10.1044/2024_JSLHR-24-00474
eng
2,025
2
4
2,025
1
29
[PURPOSE] This study explores the effects of water intake and a hyaluronic acid (HA)-containing lozenge on acoustic measurements and vocal oscillation patterns investigated after a vocal loading test (VLT). [METHOD] Ten healthy subjects (five females, five males) read out loud a standardized text for 10 min at a target...
null
0.836
164
Linguistics and Language; Speech and Hearing; Medicine
Health Professions; Medicine; Social Sciences
2,024
39,879,199
HIV-1 resistance mutations and genetic diversity among children failing antiretroviral treatment in five healthcare facilities in Benin, West Africa.
PloS one
PLoS One
20
1
10.1371/journal.pone.0317882
eng
2,025
null
null
2,025
1
29
[BACKGROUND] Antiretroviral treatment increases the risk of accumulation of resistance mutations that negatively impact the possibilities of future treatment. This study aimed to present the frequency of HIV-1 antiretroviral resistance mutations and the genetic diversity among children with virological failure in five ...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
39,878,757
Evaluation of the utility of the sFlt-1/PlGF ratio in pregnancy complicated by pre-eclampsia - single-center study. Preliminary analysis.
Ginekologia polska
Ginekol Pol
96
2
10.5603/gpl.101484
eng
2,025
null
null
2,025
1
29
[OBJECTIVES] To evaluate relationship between sFlt-1/PlGF ratio, clinical characteristics and outcomes of pre-eclampsia. [MATERIAL AND METHODS] Retrospective analysis of 29 pregnant women with pre-eclampsia who had measured sFlt-1/PlGF ratio was conducted using electronic medical records from Obstetrics and Perinatolog...
clinical laboratory test; eclampsia; placenta growth factor; pre-eclampsia; sFLT-1 protein
0.399
33
Obstetrics and Gynecology
Medicine
2,024
39,878,306
Clinical outcomes and feasibility of implementing outpatient labor induction with misoprostol: A prospective cohort study.
Acta obstetricia et gynecologica Scandinavica
Acta Obstet Gynecol Scand
104
4
10.1111/aogs.15029
eng
2,025
4
null
2,025
1
29
[INTRODUCTION] In response to the increasing rates of induction of labor (IOL), outpatient IOL has emerged as a potential approach to enhance women's satisfaction while reducing costs and staffing requirements. There is a growing interest in oral misoprostol as an outpatient IOL method, particularly in the Nordic regio...
birth; induction of labor; maternity care; misoprostol; obstetrics; outpatient labor induction
1.274
126
Medicine; Obstetrics and Gynecology
Medicine
2,024
39,878,108
Trafficking of Muscarinic 1 Acetylcholine Receptor Regulated by VPS35 in Alzheimer's Disease.
Current Alzheimer research
Curr Alzheimer Res
21
10
10.2174/0115672050356990250111200217
eng
2,024
null
null
null
null
null
[INTRODUCTION] Muscarinic 1 acetylcholine receptor (M1AChR) is a member of the Gprotein- coupled receptor superfamily, with the dysfunction being linked to the onset of Alzheimer's Disease (AD). [AIMS] Retromer complex with Vacuolar Protein Sorting-35 (VPS35) as the core plays an important role in the transport of biol...
Alzheimer's disease; muscarinic 1 acetylcholine receptors; retromer complex; trafficking.; vacuolar protein sorting-35
null
null
null
null
null
39,877,649
Elevated Plasma CXCL8 Concentrations in Significant Fibrosis but Not in Subclinical Rejection After Adult Liver Transplantation.
Transplantation direct
Transplant Direct
10
3
10.1097/TXD.0000000000001592
eng
2,024
3
null
2,024
2
21
[BACKGROUND] The noninvasive detection of subclinical graft injury including subclinical T cell-mediated rejection (subTCMR) is one of the unresolved challenges after liver transplantation. Recently, serum C-X-C motif chemokine ligand 8 (CXCL8) was proposed as a highly accurate marker of subTCMR in pediatric liver tran...
null
0.694
35
Transplantation
Medicine
2,024
39,877,525
Assessment of Left Ventricular function and Aortic blood flow in children with Tetralogy of Fallot (TOF) attending two health institutions in Enugu Metropolis.
Malawi medical journal : the journal of Medical Association of Malawi
Malawi Med J
36
4
10.4314/mmj.v36i4.7
eng
2,025
1
null
2,025
1
13
[BACKGROUND] Children with Tetralogy of Fallot (TOF) usually present with right heart abnormalities, however much is not known if these children presents with left ventricular dysfunction. [OBJECTIVES] This article is aimed to ascertain the left ventricular function of children with TOF compared with those without any ...
Left ventricular function; TOF; children; echocardiography
0.342
30
Medicine
Medicine
2,024
39,877,507
Assessment of COVID-19 Vaccine Knowledge, Uptake, and Factors Influencing its Uptake Among Medical Students at the University of Jos.
Nigerian medical journal : journal of the Nigeria Medical Association
Niger Med J
65
6
10.60787/nmj.v65i6.555
eng
2,024
null
null
2,025
1
10
[BACKGROUND] COVID-19 vaccination is crucial to containing the pandemic. COVID-19 vaccine knowledge, attitudes, and uptake among medical students are vital, as they are future healthcare professionals expected to promote vaccination. This study assessed the knowledge of the COVID-19 vaccine, its uptake, and associated ...
COVID-19 Vaccine; Factors; Knowledge; Medical Students; Uptake
null
null
null
null
null
39,877,270
Kinematic and muscle co-activation patterns in the dominant arm across forehand stroke phases in wheelchair tennis.
Frontiers in bioengineering and biotechnology
Front Bioeng Biotechnol
12
null
10.3389/fbioe.2024.1518091
eng
2,024
null
null
2,025
1
14
[OBJECTIVE] This study investigated upper limb kinematics and muscle co-activation in wheelchair tennis players during the forehand stroke. By analyzing linear and angular kinematic variables alongside muscle co-activation patterns, the study aimed to provide insights into the biomechanical mechanisms supporting foreha...
EMG; biomechanics; disability; physical activity; wearable sensors
0.974
119
Biomedical Engineering; Biotechnology; Histology; Bioengineering
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Engineering; Medicine
2,024
39,877,143
Parental Acceptance of Moderate Sedation and Associated Techniques for Behavior Management in Saudi Arabia: A Cross-Sectional Study.
Patient preference and adherence
Patient Prefer Adherence
19
null
10.2147/PPA.S499568
eng
2,025
null
null
2,025
1
24
[PURPOSE] This study aimed to evaluate the acceptance of moderate sedation (MS) as a behavior guidance technique (BGT) method among Saudi parents, and also assess their acceptance of other BGTs, including parental separation, papoose board (PB), and nitrous oxide (N2O), used in conjunction with MS. [PATIENTS AND METHOD...
child; dental anxiety; dental care; moderate sedation; parental acceptance; questionnaire
0.693
74
Pharmacology, Toxicology and Pharmaceutics; Social Sciences; Health Policy; Medicine
Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,024
39,876,527
Adult Scissor Bite Case Treatment With Moving Teeth Through Maxillary Sinus.
Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
J Esthet Restor Dent
37
6
10.1111/jerd.13424
eng
2,025
6
null
2,025
1
28
[OBJECTIVE] This case report demonstrates the orthodontic treatment to correct a severe scissor bite and occlusal disharmony in a 26-year-old female patient, including the use of temporary anchorage devices (TADs) and fixed orthodontic appliances. [CLINICAL CONSIDERATIONS] Severe scissor bite is associated with vertica...
3D analysis; maxillary sinus; molar intrusion; scissor bite; temporary anchorage devices (TADs)
1.437
79
Dentistry
Dentistry
2,024
39,876,009
Global, regional, and national burdens of type 1 and type 2 diabetes mellitus in adolescents from 1990 to 2021, with forecasts to 2030: a systematic analysis of the global burden of disease study 2021.
BMC medicine
BMC Med
23
1
10.1186/s12916-025-03890-w
eng
2,025
1
29
2,025
1
29
[BACKGROUND] Adolescent diabetes is one of the major public health problems worldwide. This study aims to estimate the burden of type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) in adolescents from 1990 to 2021, and to predict diabetes prevalence through 2030. [METHODS] We extracted epidemiologic dat...
Adolescent; Diabetes mellitus; Disease burden
2.846
199
Medicine
Medicine
2,024
39,876,003
Reductive acetogenesis is a dominant process in the ruminant hindgut.
Microbiome
Microbiome
13
1
10.1186/s40168-024-02018-1
eng
2,025
1
28
2,025
1
28
[BACKGROUND] The microbes residing in ruminant gastrointestinal tracts play a crucial role in converting plant biomass to volatile fatty acids, which serve as the primary energy source for ruminants. This gastrointestinal tract comprises a foregut (rumen) and hindgut (cecum and colon), which differ in structures and fu...
Acetogens; Fermentation pathway; Hydrogenase; Methanogenesis; Molecular hydrogen
4.117
163
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,024
39,875,979
Economic loss attributable to premature deaths and morbidity among adolescents in India and its states.
BMC medicine
BMC Med
23
1
10.1186/s12916-025-03895-5
eng
2,025
1
29
2,025
1
29
[BACKGROUND] India's large youth population presents a significant opportunity to harness the demographic dividend. The disease burden in adolescents could be a hindrance for the future economy if not appropriately addressed. [METHODS] We utilised the data on the number of adolescent deaths and attributable years lived...
Adolescent; Death; Disease burden; Economic; India; Loss of output; Morbidity
2.846
199
Medicine
Medicine
2,024
39,875,949
Assessing the role of medical entomology in general medicine education in Iran: expert perspectives and curriculum implications.
BMC medical education
BMC Med Educ
25
1
10.1186/s12909-025-06713-x
eng
2,025
1
28
2,025
1
28
[INTRODUCTION] The Ministry of Health, Treatment and Medical Education in Iran has tried integrating the primary science curriculum with the clinical program. This means educational reform has been implemented in most medical schools in Iran. In the study of the medical entomology Discipline, prioritization of educatio...
Curriculum implications; Entomology disciplines; Experts; General medicine; Medical entomology; Program review
0.947
107
Education; Medicine
Medicine; Social Sciences
2,024
39,875,910
Which dietary shifts to improve nutritional quality while reducing diet cost in the French West Indies?
Nutrition journal
Nutr J
24
1
10.1186/s12937-024-01068-3
eng
2,025
1
28
2,025
1
28
[BACKGROUND] The French West Indies are facing increasing rates of obesity and diet-related chronic diseases. Food prices are more than 30% higher compared with mainland France, while a large part of the population is socioeconomically disadvantaged. The affordability of a healthy diet is a key issue. [OBJECTIVE] To id...
Diet affordability; Diet optimization; Economical access to food; Food consumption; Food security; French overseas territories; Linear programming; Nutrition
1.221
119
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
39,875,900
Identification of strengths and weaknesses of the healthcare system for persons living with rare diseases in Catalonia (Spain), and recommendations to improve its comprehensive attention: the "acERca las enfermedades raras" project.
Orphanet journal of rare diseases
Orphanet J Rare Dis
20
1
10.1186/s13023-024-03518-x
eng
2,025
1
29
2,025
1
29
[BACKGROUND] Rare diseases (RDs) are a heterogeneous group of complex and low-prevalence conditions in which the time to establish a definitive diagnosis is often too long. In addition, for most RDs, few to no treatments are available and it is often difficult to find a specialized care team. [OBJECTIVES] The project "...
Comprehensive care; Focus group; Healthcare system; Patient journey; Person living with a rare disease; Rare diseases
1.269
143
Genetics; Medicine; Pharmacology
Medicine
2,024
39,875,789
Sleeve Gastrectomy Versus Semaglutide for Weight Loss in a Severely Obese Minority Cohort: A Propensity-Matched Study.
Obesity surgery
Obes Surg
35
3
10.1007/s11695-025-07712-z
eng
2,025
3
null
2,025
1
29
[BACKGROUND] The rising obesity rates in the USA have led to a surge in various weight loss treatments. Glucagon-like peptide-1 (GLP-1) analogues have shown promise in reducing weight but primarily studied in Caucasian populations. Sleeve gastrectomy (SG) has already proven successful weight loss outcomes. This study a...
Healthcare disparities; Medical weight loss; Sleeve gastrectomy
1.148
164
Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics; Surgery
Medicine; Nursing
2,024
39,875,720
The role of cardiac sympathetic denervation for ventricular arrhythmias: an updated systematic review and meta-analysis.
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
J Interv Card Electrophysiol
68
2
10.1007/s10840-025-01997-x
eng
2,025
3
null
2,025
1
29
[INTRODUCTION] The role of the sympathetic nervous system in the initiation and continuation of ventricular tachyarrhythmias (VTA) is well established. However, whether CSD reduces implantable cardioverter-defibrillator (ICD) shocks and recurrent VTA is still uncertain. [METHODS] A comprehensive literature search was p...
Cardiac denervation; Cardiac sympathectomy; Sympathetic denervation; Ventricular fibrillation; Ventricular tachycardia
0.847
66
Cardiology and Cardiovascular Medicine; Medicine; Physiology
Medicine
2,024
39,874,722
Nomogram vs. Depth of invasion for predicting occult lymph node metastasis in cT1-2N0 buccal squamous cell carcinoma.
Oral oncology
Oral Oncol
162
null
10.1016/j.oraloncology.2025.107206
eng
2,025
3
null
2,025
1
27
[OBJECTIVE] To develop a nomogram prediction model for occult lymph node metastasis (LNM) in patients with cT1-2N0 buccal squamous cell carcinoma (BSCC), then to compare its predictive efficacy against depth of invasion (DOI). [METHODS] Clinical data were retrieved for patients undergoing primary tumor resection and ne...
Buccal squamous cell carcinoma; Lasso regression; Nomogram; Occult lymph node metastasis; Prediction
1.326
143
Oncology; Oral Surgery; Cancer Research
Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine
2,024
39,874,555
Outcomes of 100 Squamous Cell Carcinomas of the Upper Limb: 100 Squamous Cell Carcinomas of the Upper Limb.
Annals of plastic surgery
Ann Plast Surg
94
3
10.1097/SAP.0000000000004225
eng
2,025
3
1
2,025
1
27
[BACKGROUND] Rates of recurrence, metastases, and mortality for squamous cell carcinoma (SCC) of the upper limb have not been clearly defined. [OBJECTIVE] We aimed to characterize these tumors and assess the long-term outcomes, comparing with current literature. [METHODS AND MATERIALS] A retrospective review was perfor...
null
0.598
112
Surgery
Medicine
2,024
39,874,326
Heart rate and blood pressure in soccer players differing in sports qualification.
Wiadomosci lekarskie (Warsaw, Poland : 1960)
Wiad Lek
77
12
10.36740/WLek/195549
eng
2,024
null
null
null
null
null
[OBJECTIVE] Aim: To investigate the effects of exercise training on heart rate and blood pressure in soccer players of different skill levels. [PATIENTS AND METHODS] Materials and Methods: 693 soccer players with different sports qualifications were studied. Heart rate (HR) and blood pressure (BP) were measured at rest...
soccer players; sports qualification; bradycardia; hypotonic and hypertensive states; tachycardia
null
null
null
null
null
39,874,004
Spatial Epidemiology of Human Papillomavirus Screening Coverage in Mexico, 2013-2019.
Asian Pacific journal of cancer prevention : APJCP
Asian Pac J Cancer Prev
26
1
10.31557/APJCP.2025.26.1.215
eng
2,025
1
1
2,025
1
1
[OBJECTIVE] We aimed to assess the coverage of a Human Papillomavirus (HPV) screening program for each of the 32 federal states of Mexico, as well as the spatial patterns for HPV infections from 2013 to 2019. [METHODS] We conducted an exploratory, ecological study on data from a national health program in Mexico during...
Human papillomavirus (HPV); Papillomavirus Infections; national health programs; public health; spatial epidemiology
0.53
98
Public Health, Environmental and Occupational Health; Epidemiology; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,873,411
Reflections on the 2024 Final Rule on Public Health Service Policies on Research Misconduct.
Accountability in research
Account Res
32
5
10.1080/08989621.2025.2451168
eng
2,025
7
null
2,025
1
28
[BACKGROUND] The Office of Research Integrity (ORI) of the U.S. Department of Health and Human Services (HHS) recently issued the 2024 Final Rule on Public Health Service Policies on Research Misconduct (42 CFR 93), the first major revision of the regulation in nearly twenty years. Much of the commentary published abou...
Research misconduct; policy; regulation; research integrity; responsible conduct of research
null
null
null
null
null
39,873,381
Intestinal epithelial PTPN23 is essential for gut barrier integrity and prevention of fatal bacterial translocation.
Journal of Crohn's colitis
J Crohns Colitis
19
2
10.1093/ecco-jcc/jjaf016
eng
2,025
2
4
null
null
null
[BACKGROUND AND AIMS] Protein tyrosine phosphatase nonreceptor type 23 (PTPN23) regulates the internalization of growth factor receptors such as the epithelial growth factor receptor (EGFR). Given the crucial function of such receptors in intestinal epithelial cells (IECs), we assessed the involvement of PTPN23 in inte...
intestinal epithelial cells; intestinal homeostasis; transcytosis
null
null
null
null
null
39,873,362
Di Huang Yi Zhi Fang improves cognitive function in APP/PS1 mice by inducing neuronal mitochondrial autophagy through the PINK1-parkin pathway.
Journal of Alzheimer's disease : JAD
J Alzheimers Dis
103
2
10.1177/13872877241299832
eng
2,025
1
null
2,025
1
28
[BACKGROUND] Alzheimer's disease (AD) is an irreversible age-related neurodegenerative condition characterized by the deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles. Di Huang Yi Zhi (DHYZ) formula, a traditional Chinese herbal compound comprising several prescriptions, demonstrates properties that im...
Alzheimer's disease; Di Huang Yi Zhi; autophagy; mitochondrial
1.166
188
Clinical Psychology; Medicine; Psychiatry and Mental Health; Geriatrics and Gerontology; Neuroscience
Medicine; Neuroscience; Psychology
2,024
39,873,292
C9orf72 Alleviates DSS‑Induced Ulcerative Colitis via the cGAS-STING Pathway.
Immunity, inflammation and disease
Immun Inflamm Dis
13
1
10.1002/iid3.70139
eng
2,025
1
null
null
null
null
[PURPOSE] C9orf72 deficiency contributes to severe inflammation in mice. Ulcerative colitis (UC) is a chronic inflammatory disorder with the shortage of clinical success. However, whether C9orf72 is involved in the progression of UC is not fully understood. This study investigated whether C9orf72 could alleviate dextra...
C9orf72; ulcerative colitis
0.814
38
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
39,873,189
Pathogenicity assessment of genetic variants identified in patients with severe hypertriglyceridemia: Novel cases of familial chylomicronemia syndrome from the Dyslipidemia Registry of the Spanish Atherosclerosis Society.
Genetics in medicine : official journal of the American College of Medical Genetics
Genet Med
27
5
10.1016/j.gim.2025.101365
eng
2,025
5
null
2,025
1
24
[PURPOSE] Genetic testing is required to confirm a diagnosis of familial chylomicronemia syndrome (FCS). We assessed the pathogenicity of variants identified in the FCS canonical genes to diagnose FCS cases. [METHODS] 245 patients with severe hypertriglyceridemia underwent next-generation sequencing. Preliminary varian...
ACMG/AMP criteria; Familial chylomicronemia syndrome; Next-generation sequencing; Severe hypertriglyceridemia; Variant pathogenicity assessment
2.683
167
Genetics; Medicine
Medicine
2,024
39,873,103
Influence of dual-cure resin-cement curing modes on gingival cytotoxicity and inflammatory responses.
Journal of dental sciences
J Dent Sci
20
1
10.1016/j.jds.2024.04.019
eng
2,025
1
null
2,024
4
30
[BACKGROUND/PURPOSE] Dual-cure resin-cements are used for various dental restorations. However, whether the curing modes of these resin-cements influence gingival inflammation remains unclear. Hence, herein, we evaluated the effects of dual-cure resin-cement curing modes on gingival cytotoxicity and inflammatory respon...
Curing modes; Cytotoxicity; Dual-cure resin-cements; Gingival tissue; Inflammatory responses
0.854
36
Dentistry
Dentistry
2,024
39,873,044
Advancing osseointegration research: A dynamic three-dimensional (3D) in vitro culture model for dental implants.
Journal of dental sciences
J Dent Sci
20
1
10.1016/j.jds.2024.06.018
eng
2,025
1
null
2,024
7
3
[BACKGROUND/PURPOSE] In-vitro studies are essential for understanding cellular responses, but traditional culture systems often neglect the three-dimensional (3D) structure of real implants, leading to limitations in cellular recruitment and behavior largely governed by gravity. The objective of this study was to pione...
Hydrophilic materials; Osseointegration; Osteoblasts; Surface properties
0.854
36
Dentistry
Dentistry
2,024
39,872,991
Magnetic Resonance imaging evaluation of the distance to the popliteal artery in arthroscopic popliteus tendon versus posterior cruciate ligament reconstruction.
Journal of orthopaedics
J Orthop
66
null
10.1016/j.jor.2025.01.007
eng
2,025
8
null
2,025
1
3
[PURPOSE] Wide acceptance of arthroscopically treating posterolateral corner injuries has not occurred. There remains a fear of neurovascular (NV) injury while arthroscopically performing these reconstructions. The study's aim is to compare on Magnetic Resonance Scans the distance of the tibial tunnel in an arthroscopi...
Arthroscopic popliteus bypass; Knee instability; Popliteus tendon; Posterolateral corner
0.67
41
Orthopedics and Sports Medicine
Medicine
2,024
39,872,647
Natural Causes of Sports- and Recreation-Related Deaths in the General Population: A 14-Year Review in Québec, Canada.
CJC open
CJC Open
7
1
10.1016/j.cjco.2024.09.002
eng
2,025
1
null
2,024
9
10
[BACKGROUND] This study analyzed trends in the frequencies and rates of natural deaths associated with sport and recreation activities in Québec, Canada, from January 2006 to December 2019, and investigated their etiology and characteristics. [METHODS] This descriptive retrospective study utilized data from coroner rep...
null
0.65
23
Cardiology and Cardiovascular Medicine
Medicine
2,024
39,872,645
A Hybrid Rehabilitation Program for Adults with Peripheral Artery Disease (HY-PAD): A Pre-Post Intervention Study to Assess Its Feasibility.
CJC open
CJC Open
7
1
10.1016/j.cjco.2024.09.017
eng
2,025
1
null
2,024
10
4
[BACKGROUND] Supervised exercise programs improve walking impairment and quality of life (QoL) in patients with peripheral artery disease (PAD). However, such programs are underutilized, due to their limited accessibility. A feasible and effective exercise program is needed. This study assessed the feasibility of a hyb...
null
0.65
23
Cardiology and Cardiovascular Medicine
Medicine
2,024
39,872,084
Reverse-flow Flaps of the Medial Plantar Region: Review of the Literature With Case Report.
Plastic and reconstructive surgery. Global open
Plast Reconstr Surg Glob Open
13
1
10.1097/GOX.0000000000006471
eng
2,025
1
null
2,025
1
27
[BACKGROUND] Many variations of the reverse flap design elevated on the medial plantar region have emerged since its introduction. Our aim was to review the literature to provide a broader understanding of the various iterations of the reversed blood-flow flap raised on the medial plantar region. Second, we wished to a...
null
0.676
57
Surgery
Medicine
2,024
39,871,677
Exploring the progress and trends of immunotherapy for type 1 diabetes: A comprehensive bibliometric analysis spanning nearly two decades.
Obesity reviews : an official journal of the International Association for the Study of Obesity
Obes Rev
26
5
10.1111/obr.13888
eng
2,025
5
null
2,025
1
28
[INTRODUCTION] Immunotherapy is a crucial treatment for type 1 diabetes (T1D), yet analyses focusing on research priorities and trends in this field are limited. Therefore, this study employs bibliometric methods to systematically explore the current research status of immunotherapy for T1D. [METHODS] Based on the Web ...
bibliometric analysis; immune checkpoint inhibitor; immunotherapy; type 1 diabetes; visualization
3.005
210
Endocrinology, Diabetes and Metabolism; Public Health, Environmental and Occupational Health
Medicine
2,024
39,871,299
Distinct phenotypes of patients and healthcare resource utilization after hospitalization for COVID-19: an observational study.
BMC health services research
BMC Health Serv Res
25
1
10.1186/s12913-025-12308-5
eng
2,025
1
27
2,025
1
27
[BACKGROUND] Little is known about postdischarge healthcare resource use (HCU) among patients hospitalized for coronavirus disease 2019 (COVID-19). The objective was to identify distinct profiles of patients based on postdischarge cares. [METHODS] This was a retrospective cohort study using the French National Health S...
Cluster analysis; Healthcare resource use; SARS-C
1.174
157
Health Policy
Medicine
2,024
39,871,290
Supporting students through the COVID-19 pandemic: the perspectives of food pantry workers.
BMC nutrition
BMC Nutr
11
1
10.1186/s40795-025-01009-1
eng
2,025
1
27
2,025
1
27
[BACKGROUND] College students in the United States are disproportionately impacted by food insecurity, which is associated with diminished health outcomes and poor academic performance. One key resource to support students through periods of food insecurity are on-campus food pantries, which distribute food, personal h...
COVID-19; College students; Colleges and universities; On-campus food pantry; Qualitative research
0.656
36
Medicine; Nutrition and Dietetics; Public Health, Environmental and Occupational Health; Endocrinology, Diabetes and Metabolism
Medicine; Nursing
2,024
39,871,244
Impact of family socio-economic status on the prognosis of heart transplantation in children.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-21363-w
eng
2,025
1
27
2,025
1
27
[BACKGROUND] Low family socio-economic status is a known factor that can contribute to increased mortality for patients with cardiovascular disease. However, in developing countries, the prognostic impact of socio-economic level on pediatric HTx is unclear. [METHODS] We conducted a retrospective cohort analysis of chil...
Children; Heart transplantation; Prognosis; Socio-economic status
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
39,871,230
A grounded theory study on medical students' proxy online health information seeking behavior.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-21394-3
eng
2,025
1
27
2,025
1
27
[BACKGROUND] Although Internet has become the main way of access to health and medical information for most young people today, it might not be the case with older people. The elderly that have difficulty using the Internet rely largely on their family members to obtain and evaluate online health and medical informatio...
Family members; Grounded theory; Internet; Medical students; Proxy online health information seeking behavior
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
39,871,217
Physical, chemical and biological properties of MTA Angelus and novel AGM MTA: an in vitro analysis.
BMC oral health
BMC Oral Health
25
1
10.1186/s12903-025-05517-1
eng
2,025
1
27
2,025
1
27
[INTRODUCTION] Mineral trioxide aggregate (MTA) is a calcium silicate-based cement that has changed conventional dental therapeutic approaches. This study aimed to evaluate physical, chemical and biological properties of novel AGM MTA, in comparison with MTA Angelus. [METHODS] The samples were prepared according to the...
Calcium ion release; Cytotoxicity; Dental materials; MTA-Angelus; Materials testing; Mineral trioxide aggregate; Radiopacity; Setting time; Toxicity; pH analysis
0.843
80
Dentistry
Dentistry
2,024
39,871,211
Evaluation of placental growth factor, Vitamin D, and systemic inflammatory index as predictive biomarkers for preeclampsia severity: a retrospective cohort study.
BMC pregnancy and childbirth
BMC Pregnancy Childbirth
25
1
10.1186/s12884-025-07187-x
eng
2,025
1
27
2,025
1
27
[AIM] Our study aimed to evaluate the predictive value of Placental growth factor (PlGF), Vitamin D, and systemic inflammatory index for assessing preeclampsia risk and severity. [MATERIALS AND METHODS] This retrospective cohort study included 457 pregnant individuals who delivered at our hospital between March 2023 an...
Pan-Immune Inflammation Value; Placental Growth Factor; Preeclampsia; Risk Prediction; Vitamin D
1.069
122
Obstetrics and Gynecology
Medicine
2,024
39,871,143
Antibiotic susceptibility and molecular characterization based on whole-genome sequencing of Staphylococcus aureus causing invasive infection in children and women living in Southwest China during 2018-2023.
BMC microbiology
BMC Microbiol
25
1
10.1186/s12866-025-03758-2
eng
2,025
1
27
2,025
1
27
[BACKGROUND] Staphylococcus aureus is one of the most common pathogens that colonizes human skin/mucous membranes, where it causes local infection that can progress to invasive infection, resulting in high morbidity and mortality worldwide. This study aimed to investigate the antibiotic susceptibility and molecular cha...
Spa; Staphylococcus aureus; Antibiotic resistance; Invasive infection; Multilocus sequence typing; Virulence factors; Whole-genome sequencing
1.032
147
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,024
39,870,308
Prospective Validation of CAR-HEMATOTOX and a Simplified Version Predict Survival in Patients with Large B-Cell Lymphoma Treated with Anti-CD19 CAR T-Cells: Data from CART-SIE Study.
Transplantation and cellular therapy
Transplant Cell Ther
31
4
10.1016/j.jtct.2025.01.888
eng
2,025
4
null
2,025
1
25
[BACKGROUND] Anti-CD19 CAR T-cells have revolutionized outcomes in relapsed/refractory large B-cell lymphomas. Long-term follow-up underscored the role of hematological toxicity in nonrelapse mortality, largely driven by infections, leading to the development of the CAR-HEMATOTOX (HT) score for predicting neutropenia. ...
CAR-HEMATOTOX score validation; anti-CD19 CAR T-cells; secondary primary malignancies; toxicity
null
null
null
null
null
39,870,228
β-pinene ameliorates ICV-STZ induced Alzheimer's pathology via antioxidant, anticholinesterase, and mitochondrial protective effects: In-silico and in-vivo studies.
European journal of pharmacology
Eur J Pharmacol
991
null
10.1016/j.ejphar.2025.177307
eng
2,025
3
15
2,025
1
25
[INTRODUCTION] Alzheimer's disease (AD) is a leading cause of dementia, characterized by progressive neurodegeneration and cognitive dysfunction. The disease aetiology is closely associated with proteinopathies, mitochondrial abnormalities, and elevated ROS generation, which are some of the primary markers for AD brain...
Alzheimer's disease; Antioxidants; In-silico; Memory; Mitochondrial dysfunction; Streptozotocin
1.197
210
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
39,870,074
Technical Stroke Regulations Discriminate Pacing Effectiveness During a 5-km Indoor Pool Race.
International journal of sports physiology and performance
Int J Sports Physiol Perform
20
3
10.1123/ijspp.2024-0305
eng
2,025
3
1
2,025
1
27
[PURPOSE] To investigate technical regulation mechanisms of long-distance swimmers that differentiate optimal pacing strategies and the underlying kinematic parameters. [METHODS] Twenty-one national and international swimmers were equipped with a sacrum-worn inertial measurement unit performed during 5000-m indoor Fren...
critical velocity; kinematics; open-water; race strategy; swimming
1.61
102
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,024
39,869,216
Impact of anatomical features of non-thrombotic left iliac venous compression on the development of venous leg ulcers based on CT venography.
Abdominal radiology (New York)
Abdom Radiol (NY)
50
8
10.1007/s00261-024-04772-0
eng
2,025
8
null
2,025
1
27
[PURPOSE] To explore the anatomical features of left iliac vein (LIV) in non-thrombotic venous leg ulcers (VLUs) and to identify the impact of these anatomical features on VLUs based on computed tomography venography (CTV). [METHODS] This is a retrospective, single-center study of a database (2021-2023) of 431 patients...
CT venography; Iliac venous compression syndrome; Leg ulcers; Lumbar vertebral osteophytes
0.817
91
Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging; Urology; Gastroenterology
Health Professions; Medicine
2,024
39,868,975
Operationalising a Haemophilia Gene Editing Lexicon for Practical Use.
Haemophilia : the official journal of the World Federation of Hemophilia
Haemophilia
31
2
10.1111/hae.15155
eng
2,025
3
null
2,025
1
27
[INTRODUCTION] Gene editing therapies offer the possibility of substantial improvement in treatment and quality of life for people with haemophilia (PWH) in a landscape of dynamic therapeutic advancement. Developing a common and understandable language to discuss gene editing will be essential to ensure these treatment...
CRISPR; blood coagulation disorders; gene editing; haemophilia; lexicon; visual aids
0.926
107
Medicine; Genetics; Hematology
Medicine
2,024
39,868,741
Effectiveness of gua sha with Masanggoubang oil in rats with chronic soft tissue injury.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Adv Clin Exp Med
34
3
10.17219/acem/186865
eng
2,025
3
null
null
null
null
[BACKGROUND] Chronic soft tissue injury is characterized by sterile inflammation and pain. Gua sha with Masanggoubang oil (GSMO) treatment has been found to possess anti-inflammatory and analgesic effects. [OBJECTIVES] To explore the mechanism of GSMO in chronic soft tissue injuries. [MATERIAL AND METHODS] Fifty male r...
M1 macrophage polarization; chronic soft tissue injury; gua sha with Masanggoubang oil
null
null
null
null
null
39,868,685
Prevalence and risks of sleep bruxism in children and adolescents presenting for orthodontic treatment.
European journal of orthodontics
Eur J Orthod
47
1
10.1093/ejo/cjaf002
eng
2,024
12
4
null
null
null
[OBJECTIVES] This study determined the prevalence and risks of definite sleep bruxism (SB) among children and adolescents presenting for orthodontic treatment. [METHODS] This was a cross-sectional study of 7-16-year-old subjects pursuing orthodontic treatment for the first time. The presence or absence of SB was determ...
adolescent; mandibular movement; sleep bruxism
1.012
105
Orthodontics
Dentistry
2,024
39,868,518
Insights Into Causal Effects of Genetically Proxied Lipids and Lipid-Modifying Drug Targets on Cardiometabolic Diseases.
Journal of the American Heart Association
J Am Heart Assoc
14
3
10.1161/JAHA.124.038857
eng
2,025
2
4
2,025
1
27
[BACKGROUND] The differential impact of serum lipids and their targets for lipid modification on cardiometabolic disease risk is debated. This study used Mendelian randomization to investigate the causal relationships and underlying mechanisms. [METHODS] Genetic variants related to lipid profiles and targets for lipid ...
Mendelian randomization; cardiometabolic diseases; colocalization; drug targets; eQTL; lipids
2.189
152
Cardiology and Cardiovascular Medicine
Medicine
2,024
39,868,503
Increase in IAA levels by EPSPS copy number variation relates to fitness advantage in Eleusine indica.
Pest management science
Pest Manag Sci
81
6
10.1002/ps.8637
eng
2,025
6
null
2,025
1
27
[BACKGROUND] Long-term use of chemical weed control has led to some weedy species evolving herbicide resistance traits with fitness advantage. Our previous studies revealed glyphosate resistance in an Eleusine indica population due to copy number variation of 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) comes wi...
EPSPS copy number variation; auxin; fitness advantage; glyphosate; targeted metabolome
null
null
null
null
null
39,868,373
Intraoperative circulation predict prolonged length of stay after head and neck free flap reconstruction: a retrospective study based on machine learning.
Frontiers in oncology
Front Oncol
14
null
10.3389/fonc.2024.1473447
eng
2,024
null
null
2,025
1
10
[BACKGROUND] Head and neck free flap reconstruction presents challenges in managing intraoperative circulation, potentially leading to prolonged length of stay (PLOS). Limited research exists on the associations between intraoperative circulation and PLOS given the difficulty of manual quantification of intraoperative ...
free flap reconstruction; intraoperative circulation; machine learning; prolonged length of stay; time series data
1.075
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,868,227
Proximal tubule cells contribute to the thin descending limb of the loop of Henle during mouse kidney development.
bioRxiv : the preprint server for biology
bioRxiv
null
null
10.1101/2025.01.14.633065
eng
2,025
3
24
2,025
3
24
[BACKGROUND] The thin descending limb of the loop of Henle is crucial for urine concentration, as it facilitates passive water reabsorption. Despite its importance, little is known about how this nephron segment forms during kidney development. [METHODS] We assembled a large single-cell RNA sequencing (scRNA-seq) datas...
null
null
null
null
null
null
39,867,853
Epicardial fat tissue, a hidden enemy against the early recovery of left ventricular systolic function after transcatheter aortic valve implantation.
International journal of cardiology. Heart vasculature
Int J Cardiol Heart Vasc
56
null
10.1016/j.ijcha.2024.101595
eng
2,025
2
null
2,025
1
3
[BACKGROUND] Epicardial fat tissue (EFT) is an active organ that can affect cardiac function and structure through endocrine, paracrine, and proinflammatory mechanisms. We hypothesized that greater thickness of EFT may harm the recovery of left ventricular (LV) systolic function in patients with severe aortic stenosis ...
Epicardial fat tissue; Global longitudinal strain; Severe aortic stenosis; Transcatheter aortic valve implantation
null
null
null
null
null
39,867,810
Severe gastrointestinal symptoms during first year after laparoscopic cholecystectomy.
Pakistan journal of medical sciences
Pak J Med Sci
41
1
10.12669/pjms.41.1.10125
eng
2,025
1
null
null
null
null
[BACKGROUND AND OBJECTIVE] Many patients after cholecystectomy, develop gastrointestinal (GI) symptoms and are worried. The objective of this study was to find out the risk factors for severe GI symptoms following laparoscopic cholecystectomy (LC) during first year of follow-up. [METHODS] It is a multi-center prospecti...
Cholecystitis; Cholelithiasis; Gastrointestinal symptoms; Laparoscopic cholecystectomy
null
null
null
null
null
39,867,791
Study protocol for a randomized control trial investigating the effectiveness of a multifaceted mHealth approach on adherence to antihypertensive treatment among patients in Pakistan.
Pakistan journal of medical sciences
Pak J Med Sci
41
1
10.12669/pjms.41.1.9272
eng
2,025
1
null
null
null
null
[BACKGROUND AND OBJECTIVES] Poor medication adherence is an essential contributor to Pakistan's high prevalence of uncontrolled hypertension. This study will be aimed to assess the efficacy of a one-of-a-kind developed intervention in improving medication adherence and treatment outcomes in hypertension patients. [METH...
Hypertension; Interventions; Medication adherence; Mobile Health; mHealth
null
null
null
null
null
39,881,834
Evaluation of Skin Recovery after Fractional CO2 Laser Treatment Lichen Sclerosus Using Multimodal Optical Coherence Tomography.
Sovremennye tekhnologii v meditsine
Sovrem Tekhnologii Med
16
4
10.17691/stm2024.16.4.02
eng
2,024
null
null
2,024
8
30
[UNLABELLED] The aim of the study is to demonstrate the effect of fractional CO2 laser treatment on vulvar skin in lichen sclerosus using multimodal optical coherence tomography (MM OCT). [MATERIALS AND METHODS] The study included 3 clinical cases of vulvar lichen sclerosus (VLS) (histologically classified as early, ea...
MM OCT; OCT signal attenuation coefficient; angiography; fractional CO2 laser; lymphangiography; multimodal optical coherence tomography; vulvar lichen sclerosis
null
null
null
null
null
39,916,953
Efficacy and safety of PD-1 inhibitors as second-line treatment for advanced squamous esophageal cancer: a systematic review and network meta-analysis with a focus on PD-L1 expression levels.
Frontiers in immunology
Front Immunol
15
null
10.3389/fimmu.2024.1510145
eng
2,024
null
null
2,025
1
23
[BACKGROUND] PD-1 inhibitors have shown promising efficacy in enhancing OS and AEs as second-line therapies for patients with advanced esophageal squamous cell carcinoma (ESCC). However, there remains no clear consensus on which PD-1 inhibitor provides the best balance between efficacy and safety. To address this key i...
efficacy; esophageal squamous cell carcinoma (ESCC); immune checkpoint inhibitors (ICIs); network meta-analysis; safety
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
39,916,803
Energy intake insufficiency due to underestimated energy requirement by common predictive formulas can be identified by urinary amino acid levels in advanced heart failure.
Frontiers in nutrition
Front Nutr
11
null
10.3389/fnut.2024.1504031
eng
2,024
null
null
2,025
1
23
[BACKGROUND] Elevated resting energy expenditure (REE) promotes cachexia, worsening prognosis in patients with advanced heart failure (HF). However, adequate assessment of energy balance is challenging because of unvalidated common prediction methods and unestablished determinants of REE, resulting in a lack of biomark...
advanced heart failure; histidine excretion; prediction model; resting energy expenditure; urinary amino acids
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
39,916,714
State and county level legislative approaches to address racial/ethnic health inequities in Maryland (2012-2021).
Frontiers in public health
Front Public Health
13
null
10.3389/fpubh.2025.1473971
eng
2,025
null
null
2,025
1
23
[INTRODUCTION] Public policies and legislative approaches are used to address racial health inequities. While most recent studies examine federal and state-level legislative activity, a paucity of analyses characterize policies enacted in a single state and across local jurisdictions. To address this gap, we identify r...
legislative approaches; local level policy; racial disparities; racial health inequities; state policy; structural racism
1.027
119
Public Health, Environmental and Occupational Health
Medicine
2,024
39,916,706
Global, regional, and national burden of type 2 diabetes mellitus caused by high BMI from 1990 to 2021, and forecasts to 2045: analysis from the global burden of disease study 2021.
Frontiers in public health
Front Public Health
13
null
10.3389/fpubh.2025.1515797
eng
2,025
null
null
2,025
1
23
[OBJECTIVE] To produce estimates of the global burden of type 2 diabetes mellitus (T2DM) caused by high body mass index (high BMI) and its impact for 2021 and projections for 2045. [METHODS] We downloaded data from the Global Burden of Disease Study 2021(GBD 2021) to estimate the disease burden of T2DM caused by high B...
deaths; disability-adjusted life years (DALYs); global burden of diseases (GBD); high body mass index (high BMI); socio-demographic index (SDI); type 2 diabetes mellitus (T2DM)
1.027
119
Public Health, Environmental and Occupational Health
Medicine
2,024
39,916,673
Women in oral and maxillofacial surgery: the Australasian experience.
ANZ journal of surgery
ANZ J Surg
95
4
10.1111/ans.19422
eng
2,025
4
null
2,025
2
7
[BACKGROUND] There continues to be an underrepresentation of women in oral and maxillofacial surgery (OMS) despite an increase in the number of female medical and dental students. This study aims to characterize the number of female OMS surgeons and the number of female specialists among surgical and dental specialties...
dental specialties; gender equity; general surgery; oral and maxillofacial surgery
0.483
89
Surgery; Medicine
Medicine
2,024
39,916,501
Association of metabolic dysfunction-associated fatty liver disease with white matter hyperintensity and cognitive decline: A longitudinal cohort study.
Diabetes, obesity & metabolism
Diabetes Obes Metab
27
4
10.1111/dom.16232
eng
2,025
4
null
2,025
2
6
[AIMS] Metabolic dysfunction-associated fatty liver disease (MAFLD) has recently been proposed to describe the hepatic steatosis associated with metabolic abnormalities. Substantial evidence has shown that hepatic steatosis may be linked with cognitive impairment and dementia. This study aimed to clarify the associatio...
cognitive decline; fatty liver; metabolic syndrome; white matter
null
null
null
null
null
39,916,494
Immunogenicity and safety of a live attenuated varicella vaccine in healthy subjects aged between 13 to 55 years: a double-blind, randomized, active-controlled phase III clinical trial in China.
Expert review of vaccines
Expert Rev Vaccines
24
1
10.1080/14760584.2025.2457463
eng
2,025
12
null
2,025
2
7
[BACKGROUND] Adolescents and adults who contract chickenpox are at a higher risk of severe complications. Vaccination with the varicella vaccine (VarV) effectively prevents chickenpox. [RESEARCH DESIGN AND METHODS] In this phase III, single-center, randomized, double-blind, active-controlled trial, 1,200 healthy partic...
Varicella vaccine; adolescents; adults; immunogenicity; phase III; safety
1.255
112
Drug Discovery; Pharmacology; Immunology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Pharmacology, Toxicology and Pharmaceutics
2,024
39,916,389
Disparities in consent to adjuvant radiotherapy in primary glioblastoma: a population-based study.
Expert review of anticancer therapy
Expert Rev Anticancer Ther
null
null
10.1080/14737140.2025.2464935
eng
2,025
2
12
2,025
2
12
[BACKGROUND] Despite adjuvant external beam radiation therapy (EBRT) has long been the standard treatment for glioblastoma (GBM), a significant subset of patients chooses to refuse it. We aimed to investigate the factors influencing EBRT refusal in GBM. [RESEARCH DESIGN AND METHODS] Patients with GBM were identified fr...
Glioblastoma; SEER; prognosis; radiotherapy; refusal
0.926
88
Oncology; Pharmacology
Medicine
2,024
39,915,908
Caloric Restriction Preserves BBB Integrity After Transient Focal Cerebral Ischemia Through Reducing Neutrophil Infiltration.
CNS neuroscience & therapeutics
CNS Neurosci Ther
31
2
10.1111/cns.70257
eng
2,025
2
null
null
null
null
[AIMS] Caloric restriction is a health-promoting lifestyle that has been reported to protect both white and gray matter in cases of ischemic stroke. This study will explore the underlying mechanism of restricted feeding (RF) and provide a theoretical basis for precise clinical treatment of stroke. [METHODS] In this stu...
caloric restriction; neutrophils; stroke
null
null
null
null
null
39,915,855
An idiopathic left internal iliac artery aneurysm in an 11-year-old boy: a case report.
Journal of medical case reports
J Med Case Rep
19
1
10.1186/s13256-025-05050-3
eng
2,025
2
6
2,025
2
6
[BACKGROUND] Idiopathic isolated aneurysms in pediatric patients are rare and present significant diagnostic and therapeutic challenges owing to their low incidence, small anatomical size, and the associated risks of injury to surrounding structures. Timely diagnosis and the selection of the most appropriate interventi...
Case report; Idiopathic aneurysm; Iliac artery aneurysm; Pediatric aneurysm; Vascular surgery
0.31
43
Medicine
Medicine
2,024
39,915,306
In Vivo Discrimination of Iodine and Tantalum-Based Liquid Embolics After Intracranial or Spinal Embolization Using Photon-Counting Detector CT.
Clinical neuroradiology
Clin Neuroradiol
null
null
10.1007/s00062-025-01502-x
eng
2,025
2
6
2,025
2
6
[PURPOSE] In vitro differentiation of iodine and tantalum-based liquid embolics post-embolization can be achieved using spectral computed tomography. This study evaluates the in vivo ability of clinical photon-counting computed tomography (PCD-CT) to distinguish these embolic agents in patients undergoing endovascular ...
Intracranial and spinal embolization; Iodine-based embolics; Material decomposition; Photon-counting CT; Tantalum-based embolics
0.921
43
Radiology, Nuclear Medicine and Imaging; Neurology
Medicine
2,024
39,915,304
Implant geometry and detection rates of prostate fiducial markers after transrectal ultrasound-guided perineal implantation for image-guided 6D-tracking in robotic stereotactic body radiotherapy.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
Strahlenther Onkol
201
8
10.1007/s00066-024-02363-y
eng
2,025
8
null
2,025
2
6
[PURPOSE] Fiducial markers (FM) are essential in prostate robotic stereotactic body radiotherapy (SBRT). Accuray® (Madison, WI, USA) provides an implantation guideline for reliable detection. We report on complication rates and analyze how the geometrical implantation quality correlated with subsequent detection rates....
Gold-Seeds; Intra-Prostatic; Quality-Assurance; SABR; Toxicity
0.692
81
Radiology, Nuclear Medicine and Imaging; Oncology
Medicine
2,024
39,915,110
A New Measure of Quantified Social Health Is Associated With Levels of Discomfort, Capability, and Mental and General Health Among Patients Seeking Musculoskeletal Specialty Care.
Clinical orthopaedics and related research
Clin Orthop Relat Res
483
4
10.1097/CORR.0000000000003394
eng
2,025
4
1
2,025
2
5
[BACKGROUND] A better understanding of the correlation between social health and mindsets, comfort, and capability could aid the design of individualized care models. However, currently available social health checklists are relatively lengthy, burdensome, and designed for descriptive screening purposes rather than qua...
null
1.339
244
Medicine; Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,024
39,915,011
RNF31 induces paclitaxel resistance by sustaining ALYREF cytoplasmic-nuclear shuttling in human triple-negative breast cancer.
Clinical and translational medicine
Clin Transl Med
15
2
10.1002/ctm2.70203
eng
2,025
2
null
null
null
null
[BACKGROUND] Resistance to paclitaxel-based chemotherapy is the major obstacle in triple-negative breast cancer (TNBC) treatment. However, overcoming paclitaxel resistance remains an unsolved problem. The present study aimed to determine whether paclitaxel treatment impairs Aly/REF export factor (ALYREF) cytoplasmic-nu...
ALYREF; paclitaxel resistance
3.03
24
Medicine; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,914,575
Association between hospital-treated infectious diseases and risk of neurodegenerative disease among patients with prediabetes and diabetes: A prospective cohort study in UK Biobank.
Brain, behavior, and immunity
Brain Behav Immun
126
null
10.1016/j.bbi.2025.01.027
eng
2,025
5
null
2,025
2
4
[BACKGROUND] Previous evidence suggests that infectious diseases may contribute to the development of neurodegenerative diseases (NDDs) while individuals with hyperglycemia may be at increased risk for both infection and NDDs due to dysregulated inflammation levels. This study aimed to examine the association between h...
Cohort; Infections disease; Neurodegeneration; Prediabetes and diabetes
2.704
207
Behavioral Neuroscience; Endocrine and Autonomic Systems; Immunology
Immunology and Microbiology; Neuroscience
2,024
39,913,916
Swasthya Pahal (Health for All) Using a Sustainable, Multisector, Accessible, Affordable, Reimbursable, and Tailored Informatics Framework in Rural and Urban Areas of Chennai, Tamil Nadu: Protocol for a Quantitative Study.
JMIR research protocols
JMIR Res Protoc
14
null
10.2196/39950
eng
2,025
2
6
2,025
2
6
[BACKGROUND] Noncommunicable diseases (NCDs) require a longer period of care, for which health care systems must acquire technologically advanced solutions to enhance patient care. Swasthya Pahal (health for all) is an innovative, interactive, multilingual, stand-alone, internet-enabled computer-based program that aims...
NCDs risks; Swasthya Pahal; acceptance; health behavior; healthcare; interventions; noncommunicable disease; self-management
0.527
45
Medicine
Medicine
2,024
39,913,898
Prognostics Factors to Avoid Eye Injuries in Angle Grinders.
The Journal of craniofacial surgery
J Craniofac Surg
null
null
10.1097/SCS.0000000000011108
eng
2,025
2
6
2,025
2
6
[OBJECTIVE] To analyze the clinical characteristics and prognostic factors of eye injuries caused by angle grinders over 2 years. [METHODS] Clinical data from 36 hospitalized patients (36 eyes) with eye injuries caused by angle grinders were collected. The causes of injury, types of trauma, and prognoses were analyzed....
null
0.437
90
Otorhinolaryngology; Surgery; Medicine
Medicine
2,024
39,913,504
Dry eye disease treatment improves subjective quality-of-life responses in patients with AMD, independent of disease stage.
PloS one
PLoS One
20
2
10.1371/journal.pone.0318733
eng
2,025
null
null
2,025
2
6
[PURPOSE] To determine the impact of severity of age-related macular degeneration (AMD) on subjective treatment response in patients treated for dry eye disease. [METHODS] A total of 203 eyes diagnosed with evaporative dry eye disease (DED) due to meibomian gland dysfunction were treated using the LipiFlow or MiBoFlo s...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
39,913,447
Explaining resilience in response to potential traumatic event: Sense of coherence and trajectories of anxiety during COVID-19.
Psychological trauma : theory, research, practice and policy
Psychol Trauma
null
null
10.1037/tra0001883
eng
2,025
2
6
2,025
2
6
[OBJECTIVE] Longitudinal studies have shown that most individuals can stay well in response to potential traumatic events (PTEs). However, the mechanisms underlying such resilience are still unclear. [METHOD] This study integrates Bonanno's resilience model (Bonanno, 2004) with the salutogenic approach (Antonovsky, 197...
null
1.173
86
Clinical Psychology; Social Psychology
Psychology
2,024
39,913,359
Death and disappearance: Measuring racial disparities in mortality and life expectancy among people in state prisons, United States 2000-2014.
PloS one
PLoS One
20
2
10.1371/journal.pone.0314197
eng
2,025
null
null
2,025
2
6
[BACKGROUND] Research on carceral institutions and mortality finds that people in prisons and jails have a high risk of death immediately following release from custody and that while incarcerated, racial disparities in prisoner mortality counter observed death patterns among similarly situated non-incarcerated, demogr...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
39,913,046
New evidence for miRNA testing in head and neck squamous cell cancer patients.
Clinical translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Clin Transl Oncol
27
8
10.1007/s12094-025-03854-9
eng
2,025
8
null
2,025
2
6
[PURPOSE] Prognosis of HNSCC has not changed over the last decades. MicroRNAs mediate gene expression and participate in regulating cellular biological processes. Its aberrant expression is an important event in the development of several cancers, including head and neck squamous cell cancer. The aim of the study is to...
Diagnosis; Head and neck squamous cell cancer; Liquid biopsy; MicroRNA; Monitoring; Plasma
null
null
null
null
null
39,912,759
Incidence of constrained condylar and hinged knee implants and mid- to long-term survivorship: a register-based study from the Nordic Arthroplasty Register Association (NARA).
Acta orthopaedica
Acta Orthop
96
null
10.2340/17453674.2025.42999
eng
2,025
2
6
2,025
2
6
[BACKGROUND AND PURPOSE] In complex primary total knee arthroplasty (TKA), constrained condylar knee (CCK) or rotating hinge knee (RHK) designs may be required to provide stability or address bony deficiencies. We analyzed trends in incidence of these designs in primary TKA and evaluated the mid- to long-term survivors...
null
1.15
136
Medicine; Orthopedics and Sports Medicine; Surgery
Medicine
2,024
39,912,331
Validation of an Artificial Intelligence-Powered Virtual Assistant for Emergency Triage in Neurology.
The neurologist
Neurologist
30
3
10.1097/NRL.0000000000000594
eng
2,025
5
1
2,025
5
1
[OBJECTIVES] Neurological emergencies pose significant challenges in medical care in resource-limited countries. Artificial intelligence (AI), particularly health chatbots, offers a promising solution. Rigorous validation is required to ensure safety and accuracy. Our objective is to evaluate the diagnostic safety and ...
artificial intelligence; neurology; triage
0.302
68
Medicine; Neurology
Medicine
2,024
39,912,270
One Milligram Versus Two Milligram Intramuscular Vitamin K to Prevent Late-Onset Hemorrhagic Disease in Young Infants: A Randomized Controlled Trial.
Indian pediatrics
Indian Pediatr
62
2
10.1007/s13312-025-3374-6
eng
2,025
2
15
null
null
null
[OBJECTIVE] To compare the efficacy of a standard dose (1 mg) with 2 mg vitamin K administered by intramuscular (IM) route in reducing subclinical late-onset vitamin K deficiency bleeding (VKDB) assessed using serum protein induced by vitamin K absence (PIVKA II) levels. [METHODS] This was an open-labeled randomized co...
null
0.38
63
Pediatrics, Perinatology and Child Health
Medicine
2,024
39,911,811
Association between hyperuricemia and dietary retinol intake in Southwest China: a cross-sectional study based on CHNS database.
Frontiers in nutrition
Front Nutr
12
null
10.3389/fnut.2025.1508774
eng
2,025
null
null
2,025
1
22
[BACKGROUND] Hyperuricemia is increasingly common in Southwestern China and poses significant health risks, including gout and cardiovascular disease. Retinol intake has been hypothesized to affect uric acid levels, but this relationship remains unclear. [METHODS] Data from 4,658 participants in the China Health and Nu...
CHNS; cross-sectional design; dietary retinol; hyperuricemia
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
39,911,640
Household Sanitation and Crowding Status in Addis Health and Demographic Surveillance System (Addis-HDSS) in Addis Ababa, Ethiopia.
Ethiopian journal of health sciences
Ethiop J Health Sci
34
Spec Iss 2
10.4314/ejhs.v34i2.3S
eng
2,024
12
null
null
null
null
[BACKGROUND] Access to sanitation and healthy housing conditions are essential for public health, reducing the spread of diseases and improving overall well-being. However, millions of people, particularly in low-income countries, still lack access to basic sanitation and housing facilities. This study assessed househo...
Ethiopia; Household crowding index; Sanitation
null
null
null
null
null
39,911,587
Perceptions, practices, and experiences of asthma patients and community pharmacists on short-acting beta-2 agonists inhaler use: A qualitative study.
Journal of pharmaceutical policy and practice
J Pharm Policy Pract
18
1
10.1080/20523211.2025.2455065
eng
2,025
null
null
2,025
2
4
[BACKGROUND] Short-acting beta-2 agonists (SABA) are bronchodilators that offer rapid relief for asthma patients experiencing acute symptoms. The availability of SABA inhalers without a prescription may exacerbate the overuse of SABA. This study aimed to explore the perceptions, practices, and experiences of asthma pat...
Beta-2 agonists; asthma; community pharmacist; inhalers; over-the-counter; pharmacy
0.662
35
Pharmacology, Toxicology and Pharmaceutics; Pharmacy; Health Policy
Health Professions; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024