pmid
int64
10.6M
40.8M
title
stringlengths
14
606
journal_title
stringlengths
3
239
journal_iso
stringlengths
3
51
volume
stringlengths
1
207
issue
stringclasses
726 values
doi
stringlengths
5
66
language
stringclasses
1 value
pub_date_year
float64
2k
2.03k
pub_date_month
float64
1
12
pub_date_day
float64
1
31
article_date_year
float64
2k
2.03k
article_date_month
float64
1
12
article_date_day
float64
1
31
abstract_text
stringlengths
323
8.65k
keywords
stringlengths
2
1.73k
SJR
float64
0.1
26
H index
float64
0
1.23k
categories
stringlengths
6
264
areas
stringclasses
208 values
sjr_year_source
float64
2k
2.02k
39,938,735
Females experience inferior outcomes and higher rates of revisions and complications compared to males following anatomic total shoulder arthroplasty: a systematic review and meta-analysis.
Journal of shoulder and elbow surgery
J Shoulder Elbow Surg
null
null
10.1016/j.jse.2024.12.043
eng
2,025
2
10
2,025
2
10
[BACKGROUND] To compare patient-reported outcomes, range of motion, and rates of revision surgery between male and female patients undergoing primary anatomic total shoulder arthroplasty (aTSA). [METHODS] A systematic review was performed using the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis ...
Anatomic total shoulder arthroplasty (aTSA); functional outcomes; gender disparities; patient-reported outcomes; postoperative complications; sex differences; systematic review and meta-analysis
1.741
178
Medicine; Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,024
39,938,686
Connexin 43 dephosphorylation mediates the Dchs1/YAP/TEAD signaling pathway to induce cardiac fibrosis.
Biochimica et biophysica acta. Molecular cell research
Biochim Biophys Acta Mol Cell Res
1872
3
10.1016/j.bbamcr.2025.119919
eng
2,025
3
null
2,025
2
10
[BACKGROUND] The gap junction protein connexin 43 (Cx43) has been implicated in the development of cardiac fibrosis. Our previous findings revealed that Cx43 dephosphorylation at serine 282 (S282) is related to cardiomyocyte apoptosis and arrhythmias in hearts damaged by ischemia/reperfusion. In this study, we investig...
Connexin 43; Cx43 serine 282; Dchs1; Myocardial fibrosis; YAP
null
null
null
null
null
39,938,560
Phenotype and genotype of 23 patients with hypopituitarism and pathogenic GLI2 variants.
European journal of endocrinology
Eur J Endocrinol
192
2
10.1093/ejendo/lvaf015
eng
2,025
2
1
null
null
null
[OBJECTIVE] To analyze the phenotype and genotype of patients with congenital hypopituitarism (CH) and pathogenic (P) GLI2 variants. [METHODS] A large cohort of patients with hypopituitarism was screened for GLI2 variants using a next-generation sequencing panel. Genotype-phenotype correlations were then assessed using...
CPHD; GLI2; IGHD; Kallmann syndrome; PSIS; cardiopathy; renal malformation
1.81
179
Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,938,498
Microsurgical Treatment versus Endovascular Treatment for Ruptured Intracranial Aneurysms in Elderly Patients: A Multicenter Study in Northern China.
Neuroepidemiology
Neuroepidemiology
null
null
10.1159/000544079
eng
2,025
2
12
2,025
2
12
[BACKGROUND] Management of ruptured intracranial aneurysms (RIAs) in elderly patients remains a major challenge in the treatment of cerebrovascular diseases. This study aims to provide a comprehensive analysis of the impact of microsurgical treatment (MST) and endovascular treatment (EVT) on the outcomes of elderly pat...
Complications; Elderly patients; Endovascular treatment; Microsurgical treatment; Mortality; Outcome; Ruptured intracranial aneurysms
1.391
101
Epidemiology; Neurology
Medicine
2,024
39,938,182
Effects of Reimbursement Add-On Policies on Trastuzumab and Bevacizumab Biosimilar Adoption in a Japanese Oncology Setting.
Value in health regional issues
Value Health Reg Issues
46
null
10.1016/j.vhri.2025.101090
eng
2,025
3
null
2,025
2
11
[OBJECTIVES] The Japanese government has introduced reimbursement incentive policies designed to promote biosimilar adoption for oncology biologics, including the provision of a financial incentive of ¥1500 (approximately $10) per prescription to physicians who prescribe biosimilars. This study aimed to evaluate the im...
bevacizumab; biosimilar; interrupted time series analysis; reimbursement policy; trastuzumab
0.626
31
Economics, Econometrics and Finance; Pharmacology, Toxicology and Pharmaceutics; Health Policy
Economics, Econometrics and Finance; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,938,055
Urine Metabolites of Suspected Community-Acquired Pneumonia.
The Journal of infectious diseases
J Infect Dis
232
2
10.1093/infdis/jiaf072
eng
2,025
8
14
null
null
null
[BACKGROUND] Accurate diagnosis of community-acquired pneumonia (CAP) can be challenging. Clinical findings are nonspecific, and interpretations of chest radiographs have poor interrater reliability. Pilot studies demonstrate the potential for metabolomics to identify metabolite concentrations that differentiate childr...
biomarkers; controls; metabolomic; pediatric; pneumonia
2.038
282
Immunology and Allergy; Infectious Diseases
Medicine
2,024
39,937,799
Development and psychometric testing of the family caregiver self-efficacy scale for patients in the early post-coronary artery bypass grafting.
PloS one
PLoS One
20
2
10.1371/journal.pone.0314326
eng
2,025
null
null
2,025
2
12
[BACKGROUND AND OBJECTIVES] Family caregiver self-efficacy plays an important role in improving the health and quality of life of patients in the early post-coronary artery bypass grafting (CABG). However, there is a lack of targeted self-efficacy assessment tool for caregivers of patients. Thus, the purpose of this st...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
39,937,731
Association Between Nurse Turnover and Nurses' Perception of Patient Outcomes in Acute Care Hospitals in South Korea: A Cross-Sectional Study.
Journal of nursing care quality
J Nurs Care Qual
null
null
10.1097/NCQ.0000000000000843
eng
2,025
2
11
2,025
2
11
[BACKGROUND] High turnover rates among nurses are a global concern. Previous studies show the negative impact on quality of care. [PURPOSE] The purpose of this study was to examine the relationship between nurse turnover and nurse's perceptions of patient outcomes. [METHODS] A cross-sectional study design was used. Nur...
null
null
null
null
null
null
39,937,361
Burnout levels among radiation oncology residents in Spain: a cross-sectional survey.
Clinical translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Clin Transl Oncol
27
8
10.1007/s12094-025-03862-9
eng
2,025
8
null
2,025
2
12
[PURPOSE] This study aimed to investigate the prevalence and characteristics of burnout among Radiation Oncology residents in Spain, focusing on its associated risk factors and implications for residency training. [MATERIALS AND METHODS] A cross-sectional online survey was conducted from June to September 2024, using t...
Curriculum; Radiation oncology; Research; Residency; Spanish residency
null
null
null
null
null
39,937,313
Survivorship care plan utilization in Australia and New Zealand: survivors', parents' and healthcare providers' perspectives.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
33
3
10.1007/s00520-025-09238-7
eng
2,025
2
12
2,025
2
12
[PURPOSE] As part of survivorship care, many health authorities recommend survivorship care plans (SCPs). The aim of this study was to understand survivors' SCP receipt and use, clinical/demographic factors associated with use, and providers' SCP practices. [METHODS] We surveyed Australian and New Zealand survivors of ...
Cancer; Survivor; Survivorship; Survivorship care plans; Treatment summary
1.109
143
Oncology; Rehabilitation; Oncology
Medicine; Nursing
2,024
39,937,207
Implementation of an enhanced medication access workflow within a health-system specialty pharmacy: Impact on patient and clinician experience.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Am J Health Syst Pharm
82
17
10.1093/ajhp/zxaf023
eng
2,025
8
19
null
null
null
[PURPOSE] The initiation of specialty medications is associated with patient access challenges and clinician burden. This evaluation assessed the impact on patient and clinician experience of an intervention to improve medication access by investing resources upstream of the prescribing step. [METHODS] The specialty ph...
clinician experience; medication access; patient experience; prior authorizations; specialty pharmacy
0.5
110
Pharmacy; Health Policy; Medicine; Pharmacology
Health Professions; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,936,867
Generative AI-Derived Information About Opioid Use Disorder Treatment During Pregnancy: An exploratory evaluation of GPT-4's steerability for provision of trustworthy person-centered information.
Journal of studies on alcohol and drugs
J Stud Alcohol Drugs
null
null
10.15288/jsad.24-00319
eng
2,025
2
12
2,025
2
12
[OBJECTIVE] Increasing engagement in evidence-based treatment for opioid use disorder during pregnancy is pressing. Generative artificial intelligence large language model conversational agents may support clinicians in delivering safe, accurate, and relevant information to this population. The central aim of this stud...
null
0.838
141
Health; Psychiatry and Mental Health; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,024
39,936,507
Peri-Implant Health and Perfusion Parameters in Patients After Microvascular Jaw Reconstruction: A Clinical Cohort Study.
Clinical implant dentistry and related research
Clin Implant Dent Relat Res
27
1
10.1111/cid.70012
eng
2,025
2
null
null
null
null
[INTRODUCTION] The aim of this study was to evaluate perfusion parameters and clinical features of healthy implants and implants affected by peri-implant disease in patients who had undergone microvascular jaw reconstruction. [METHODS] A total of 25 patients with 92 implants placed in microvascular transplants were inc...
laser doppler flowmetry; microvascular flap; perfusion; tissue spectrophotometry
1.315
105
Dentistry; Oral Surgery
Dentistry
2,024
39,936,136
Predicted Indirectly Recognizable T-cell Epitope (PIRCHE) Load Correlates With Rejection Events After Simultaneous Pancreas-Kidney Transplantation.
Transplantation direct
Transplant Direct
11
3
10.1097/TXD.0000000000001764
eng
2,025
3
null
2,025
2
7
[BACKGROUND] Given the lack of specificity of current blood and urine testing and the resistance/inability to perform pancreas allograft biopsies, additional noninvasive investigational tools to assess the risk for rejection are needed. This study examines the clinical impact of molecular HLA matching in a large single...
null
0.694
35
Transplantation
Medicine
2,024
39,936,075
The Prediction Model of High-Frequency Ultrasound Combined with Artificial Intelligence-Assisted Scoring System Improved the Diagnosis of Sclerosing Adenosis and Early Breast Cancer.
Breast cancer (Dove Medical Press)
Breast Cancer (Dove Med Press)
17
null
10.2147/BCTT.S483496
eng
2,025
null
null
2,025
2
7
[OBJECTIVE] The study aimed to apply an artificial intelligence (AI)-assisted scoring system, and improve the diagnostic efficiency of Sclerosing adenosis and early breast cancer. [METHODS] This study retrospectively collected adenopathy patients (156 cases) and early breast cancer patients (150 cases) in Henan Provinc...
AI; breast tumor; computer-aided diagnosis; sclerosing adenosis; ultrasound
0.954
67
Medicine; Radiology, Nuclear Medicine and Imaging; Oncology; Pharmacology
Medicine
2,024
39,935,901
The Effect of Sexuality Education During Pregnancy on Female Sexual Function: A Systematic Review and Meta-Analysis Study.
International journal of sexual health : official journal of the World Association for Sexual Health
Int J Sex Health
37
1
10.1080/19317611.2025.2453909
eng
2,025
null
null
2,025
1
29
[OBJECTIVE] This meta-analysis aimed to synthesize the effect of sexuality education during pregnancy on female sexual function. Although sexual dysfunction in pregnancy is a common problem, it is often overshadowed by other outcomes, such as pregnancy risks or birth complications. Therefore, understanding the impact o...
Meta-analysis; pregnancy; sexual education; sexual function
null
null
null
null
null
39,935,738
Epidemiological risk factors for acute kidney injury outcomes in hospitalized adult patients: a multicenter cohort study.
Clinical kidney journal
Clin Kidney J
18
2
10.1093/ckj/sfae426
eng
2,025
2
null
2,025
1
23
[BACKGROUND] Multiple studies have identified risk factors for acute kidney injury (AKI) in hospitalized patients, but less is known about factors associated with AKI severity, including non-recovery of AKI. [METHODS] Retrospective cohort study of adults (≥18 years) hospitalized between 2014 and 2017 at three US academ...
acute kidney injury; diabetes mellitus; obesity; race; risk factor
1.393
69
Nephrology; Transplantation
Medicine
2,024
39,935,568
Lactobacillus GG in the Prevention of Antibiotic-Associated Diarrhea in the Pediatric Intensive Care Unit: A Prospective Randomized, Double-Blind Placebo Controlled Intervention.
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
J Pediatr Pharmacol Ther
30
1
10.5863/1551-6776-30.1.47
eng
2,025
2
null
2,025
2
10
[OBJECTIVE] The objective of this study was to assess the efficacy of lactobacillus GG (LGG) to prevent antibiotic-associated diarrhea (AAD) in the pediatric intensive care unit (PICU). [METHODS] This was a prospective randomized, double-blind, placebo-controlled pilot trial in an academic PICU over 1 year. Patients ≤ ...
Lactobacillus; PICU; antibiotic-associated diarrhea; critical illness; pediatrics; probiotic
null
null
null
null
null
39,935,076
A Scoping Review of the Ways Gatekeepers May Hinder or Promote Opportunities for People With Intellectual and/or Developmental Disabilities to Learn About Research Participation.
Journal of intellectual disability research : JIDR
J Intellect Disabil Res
69
5
10.1111/jir.13216
eng
2,025
5
null
2,025
2
11
[BACKGROUND] Adults with intellectual and/or developmental disabilities are disproportionately excluded from participation in research, consequently increasing disparities experienced by this group. Gatekeepers, individuals who control access to research participation opportunities, may either support or pose a barrier...
developmental disability; gatekeeping; intellectual disability; recruitment; research ethics
0.807
124
Arts and Humanities; Rehabilitation; Neurology; Neurology; Psychiatry and Mental Health
Arts and Humanities; Medicine; Neuroscience
2,024
39,934,844
Application of an enhanced recovery after surgery care protocol in patients undergoing lumbar interbody fusion surgery: a meta-analysis.
Journal of orthopaedic surgery and research
J Orthop Surg Res
20
1
10.1186/s13018-025-05523-7
eng
2,025
2
11
2,025
2
11
[BACKGROUND] Enhanced recovery after surgery (ERAS) has been widely used in several surgical fields. This meta-analysis compared the clinical outcomes of the ERAS protocol and standard care (SC) in patients who underwent lumbar interbody fusion surgery. [MATERIALS AND METHODS] The PubMed, Web of Science, Cochrane Libra...
Enhanced recovery after surgery; Lumbar interbody fusion surgery; Meta-analysis; Outcomes; Standard care
0.877
75
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
39,934,288
Patients' Perceptions of Stress Urinary Incontinence Treatment: A Scoping Review of Qualitative Studies.
International urogynecology journal
Int Urogynecol J
36
6
10.1007/s00192-025-06061-w
eng
2,025
6
null
2,025
2
11
[INTRODUCTION AND HYPOTHESIS] Treatment options for female stress urinary incontinence (SUI) are often offered in a stepped-care approach. However, the shift towards patient-centred care and shared decision making (SDM) has prompted an increased interest in patients' perceptions of treatment decision making. This scopi...
Patient perceptions; Qualitative research; Shared decision making; Stress urinary incontinence; Treatment decision
0.778
109
Obstetrics and Gynecology; Urology
Medicine
2,024
39,933,995
Relapse in substance-induced psychosis and associated risk factors. A Nationwide register-linkage study from Sweden.
Addiction (Abingdon, England)
Addiction
120
7
10.1111/add.70014
eng
2,025
7
null
2,025
2
11
[BACKGROUND AND AIMS] Substance-induced psychoses (SIP) have the potential to relapse and convert into schizophrenia-spectrum disorders. However, risk factors associated with SIP relapse remain unknown. The aim of this study was to measure the incidence and risk of SIP relapse and associating risk factors. [DESIGN, SET...
ADHD; psychotic disorders; register study; relapse; substance use disorder
2.357
224
Medicine; Psychiatry and Mental Health
Medicine
2,024
39,933,751
Oral roflumilast for psoriasis: a real-world 24-week prospective cohort study.
The Journal of dermatological treatment
J Dermatolog Treat
36
1
10.1080/09546634.2025.2464107
eng
2,025
12
null
2,025
2
11
[OBJECTIVE] Psoriasis is a chronic inflammatory skin disease with significant physical and psychological burden, often associated with comorbidities such as obesity and cardiovascular disease. Current treatments include conventional systemic therapies and targeted biologic and non-biologic therapies, with several limit...
Roflumilast; obesity; psoriasis; weight loss
1.067
69
Dermatology
Medicine
2,024
39,933,556
Perceived Stress is Associated with Health Outcomes, Platelet Activation, and Oxidative Stress in COPD.
Chronic obstructive pulmonary diseases (Miami, Fla.)
Chronic Obstr Pulm Dis
12
2
10.15326/jcopdf.2024.0561
eng
2,025
3
27
null
null
null
[BACKGROUND] Individuals with chronic obstructive pulmonary disease (COPD) are disproportionately affected by social determinants of health that have been associated with worse respiratory outcomes. This study evaluates the association of perceived stress with respiratory outcomes and distinct biological mechanisms amo...
COPD; outcomes; oxidative stress; perceived stress; platelet activation
null
null
null
null
null
39,933,500
Dynamic Observation of Colonic Lesions, Commensal Microbiome, and Mycobiome Variations in Trinitrobenzene Sulfonic Acid-Induced Experimental Crohn's Disease in Rats.
Digestion
Digestion
null
null
10.1159/000543337
eng
2,025
2
11
2,025
2
11
[INTRODUCTION] Crohn's disease (CD) is an inflammatory bowel disease characterized by chronic inflammation of the entire digestive lining. Although the pathogenesis of CD remains unclear, multiple factors, especially altered microbiota, are among its causes. [METHODS] In this study, an experimental CD model was establi...
Dynamic variations; Gut microbiome; Gut mycobiome
1.111
92
Gastroenterology
Medicine
2,024
39,933,448
Complete excision and management of large hyaline-vascular pelvic Castleman's disease with coexisting cholecystolithiasis: A rare case report.
International journal of surgery case reports
Int J Surg Case Rep
128
null
10.1016/j.ijscr.2025.111019
eng
2,025
3
null
2,025
2
7
[INTRODUCTION] Castleman's disease (CD) refers to scarce lymphovascular hyperplasia categorized as unicentric (UCD) or multicentric (MCD). Retroperitoneal UCD is uncommon (6.7 %) and frequently grows undetected, making diagnosis challenging. The hypervascular nature of hyaline-vascular variant and the average larger si...
Case report; Castleman's disease; Lymphadenopathy; Pelvic mass resection; Retroperitoneal; Unicentric
0.238
31
Surgery
Medicine
2,024
39,933,273
Evaluation of factors predicting transition from prediabetes to diabetes among patients residing in underserved communities in the United States - A machine learning approach.
Computers in biology and medicine
Comput Biol Med
187
null
10.1016/j.compbiomed.2025.109824
eng
2,025
3
null
2,025
2
11
[INTRODUCTION] Over one-third of the population in the United States (US) has prediabetes. Unfortunately, underserved population in the United States face a higher burden of prediabetes compared to urban areas, increasing the risk of stroke and heart disease. There is a gap in the literature in understanding early pred...
Cardiovascular disease; Diabetes; Health outcomes; Machine learning; Prediabetes; Preventive medicine; Public health
1.447
142
Computer Science Applications; Health Informatics
Computer Science; Medicine
2,024
39,933,253
Of Lyme disease and machine learning in a One Health world.
American journal of veterinary research
Am J Vet Res
86
S1
10.2460/ajvr.24.10.0300
eng
2,025
3
1
2,025
2
11
[OBJECTIVE] Lyme disease is a vector-borne emerging zoonosis in Ontario driven by human population growth and climate change. Lyme disease is also a prime example of the One Health concept. While little can be done to immediately reverse climate change and population growth, public health must resort to health communic...
Lyme disease (LD); One Health; artificial intelligence (AI); epidemiology; forecasting
0.477
105
Veterinary; Medicine
Medicine; Veterinary
2,024
39,933,171
Smart Pharmaceutical Monitoring System With Personalized Medication Schedules and Self-Management Programs for Patients With Diabetes: Development and Evaluation Study.
Journal of medical Internet research
J Med Internet Res
27
null
10.2196/56737
eng
2,025
2
11
2,025
2
11
[BACKGROUND] With the climbing incidence of type 2 diabetes, the health care system is under pressure to manage patients with this condition properly. Particularly, pharmacological therapy constitutes the most fundamental means of controlling blood glucose levels and preventing the progression of complications. However...
GPT-4; diabetes; drug database; intelligent medication scheduling system; pharmaceutical services; self-management
1.992
214
Health Informatics
Medicine
2,024
39,932,587
Dietary patterns, nutrients, and risk of expiratory airflow limitation in children and adolescents.
European journal of nutrition
Eur J Nutr
64
2
10.1007/s00394-025-03604-1
eng
2,025
2
11
2,025
2
11
[BACKGROUND] Increasing global pediatric respiratory diseases require understanding modifiable factors affecting lung function. We explored the association between dietary patterns, nutrients and the risk of expiratory airflow limitation (EAL) in children and adolescents. [METHODS] Dietary intake was collected using a ...
Children and adolescent; Expiratory airflow limitation; FEV1; Nutrient; Plant foods pattern
1.346
125
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
39,932,500
Comparing arm-ergometry and treadmill exercise training on cardiovascular risk factors in peripheral artery disease: secondary analysis of the ARMEX trial.
International angiology : a journal of the International Union of Angiology
Int Angiol
44
1
10.23736/S0392-9590.25.05364-7
eng
2,025
2
null
2,025
2
11
[BACKGROUND] Peripheral artery disease (PAD), usually caused by atherosclerosis, is linked to high cardiovascular mortality. In this setting, a multidimensional cardiovascular rehabilitation program (CRP) comprising supervised exercise training can improve cardiovascular risk factors (CRF) control. This study compares ...
null
0.484
65
Cardiology and Cardiovascular Medicine
Medicine
2,024
39,932,387
The Role of Parental Temperament and Parent-Child Fit in Two Stuttering Therapy Programs for Preschool-Aged Children Who Stutter: A Preliminary Study.
Journal of speech, language, and hearing research : JSLHR
J Speech Lang Hear Res
68
3
10.1044/2024_JSLHR-24-00062
eng
2,025
3
5
2,025
2
11
[PURPOSE] To understand factors contributing to therapy success, this study investigated the role of parents' temperament and the fit between parents' temperament and parent-reported child behavior problems in therapy outcomes across two therapy types. [METHOD] A total of 177 children who stutter and their parents were...
null
0.836
164
Linguistics and Language; Speech and Hearing; Medicine
Health Professions; Medicine; Social Sciences
2,024
39,931,994
Transdermal Drug Delivery Systems: Integrating Modern Technology for Enhanced Therapeutics.
Current drug safety
Curr Drug Saf
null
null
10.2174/0115748863362068250122102544
eng
2,025
2
11
2,025
2
11
[BACKGROUND] In recent years, transdermal drug delivery systems (TDDS) have gained popularity as a non-invasive, patient-friendly medication delivery method. [OBJECTIVE] This review article examines the latest transdermal medication delivery developments and breakthroughs. The review begins with a brief summary of tran...
Transdermal drug delivery system (TDDS); bioavailability.; microneedles; nanocarriers; personalized medicine
0.295
43
Pharmacology; Pharmacology; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,931,985
A Scoping Review of Rho Kinase Inhibitors and their Role in Glaucoma Treatment.
Current medicinal chemistry
Curr Med Chem
null
null
10.2174/0109298673366619250113103213
eng
2,025
2
7
2,025
2
7
[OBJECTIVE] The purpose of this scoping review is to provide researchers with a comprehensive knowledge map and identify existing knowledge gaps. [INTRODUCTION] Glaucoma is the leading cause of irreversible blindness worldwide. ROCK inhibitors are a novel class of intraocular pressure-lowering drugs that specifically t...
Corticosteroids; ROCK; glaucoma; intraocular pressure; rho kinase inhibitors; trabecular meshwork
0.778
210
Biochemistry; Drug Discovery; Molecular Medicine; Organic Chemistry; Pharmacology
Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
2,024
39,931,605
Standardization of a Model of Vertebral Metastasis of Breast Cancer in CD1/Nu/Nu Mice.
Cureus
Cureus
17
1
10.7759/cureus.77291
eng
2,025
1
null
2,025
1
11
[INTRODUCTION] Breast cancer is the leading cause of cancer-related death in Mexico, with high mortality associated with spinal bone metastasis. We propose to standardize a murine model of bone metastasis to study and understand the tumor microenvironment. [MATERIALS AND METHODS] An experimental, prospective, longitudi...
4t1; breast cancer; hematogenous metastasis; pain; pet-ct; spinal cord compression
null
null
null
null
null
39,931,374
Sub-Clinical Regional Macular Changes in Self-Reported Diabetic Subjects: Vascular and Retinal Layer Analysis Using Swept-Source OCT.
Diabetes, metabolic syndrome and obesity : targets and therapy
Diabetes Metab Syndr Obes
18
null
10.2147/DMSO.S504882
eng
2,025
null
null
2,025
2
6
[AIM] To assess and compare subclinical alterations in superficial capillary plexus vessel density (SCPVD) and retinal layers thickness in the macular region between individuals with type 2 diabetes mellitus (DM) and healthy controls. [METHODS] Swept-source OCT images were obtained from 29 control subjects and 24 diabe...
FAZ; RNFL; SCPVD; age; diabetes mellitus; tomography
0.827
71
Internal Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,931,308
Looking at Social Interactions in Medical Education with Dual Eye-Tracking Technology: A Scoping Review.
MedEdPublish (2016)
MedEdPublish (2016)
14
null
10.12688/mep.20577.2
eng
2,024
null
null
2,024
12
18
[PURPOSE] Social interactions are fundamental to effective medical practice, yet assessing these complex dynamics in educational settings remains challenging. This review critically examines the emerging use of dual eye-tracking technology as a novel method to quantify, analyze, and enhance social interactions within m...
Dual Eye-Tracking; Dual mobile Eye-Tracking; Eye-Tracking; Medical Education; Scoping Review
null
null
null
null
null
39,931,262
Addressing the Alarming Rise in Pediatric Cancer Prevalence in India: A Call to Action.
Health science reports
Health Sci Rep
8
2
10.1002/hsr2.70429
eng
2,025
2
null
2,025
2
10
[BACKGROUND] Childhood cancer has become a pressing global concern, impacting over 200,000 children annually, and is projected to escalate to 21 million diagnoses by 2030. This article discusses the growing incidence of pediatric cancer in India, describes the unique obstacles it faces, and encompasses a strategy for s...
comprehensive approach; early detection; environmental factors; global prevalence; pediatric cancer
0.567
26
Medicine
Medicine
2,024
39,931,195
Spirituality and mental health - investigating the association between spiritual attitudes and psychosomatic treatment outcomes.
Frontiers in psychiatry
Front Psychiatry
15
null
10.3389/fpsyt.2024.1497630
eng
2,024
null
null
2,025
1
27
[BACKGROUND] The relationship between spirituality and mental health has garnered attention, fostering overall well-being. Spirituality, posited as a protective factor, may enhance resilience and provide meaning, thus benefiting mental health. This study aims to identify spirituality-associated factors influencing clin...
mental health; psychosomatic medicine; questionnaire; spirituality; treatment outcome
1.192
134
Psychiatry and Mental Health
Medicine
2,024
39,931,131
Association between maternal smoking during pregnancy and developmental disabilities in US children and adolescents: A cross-sectional study from NHANES.
Tobacco induced diseases
Tob Induc Dis
23
null
10.18332/tid/200339
eng
2,025
null
null
2,025
2
10
[INTRODUCTION] Maternal smoking during pregnancy is associated with placental DNA methylation and RNA expression, offspring DNA methylation, and affects the decline of mature neurons and the prenatal human brain development trajectory. [METHODS] This study is a secondary analysis of data from the National Health and Nu...
National Health and Nutrition Examination Survey; cross-sectional study; developmental disabilities; smoking during pregnancy
0.665
41
Health; Medicine; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,024
39,931,028
High-quality phenotypic and genotypic dataset of barley genebank core collection to unlock untapped genetic diversity.
GigaScience
Gigascience
14
null
10.1093/gigascience/giae121
eng
2,025
1
6
null
null
null
[BACKGROUND] Genebanks around the globe serve as valuable repositories of genetic diversity, offering not only access to a broad spectrum of plant material but also critical resources for enhancing crop resilience, advancing scientific research, and supporting global food security. To this end, traditional genebanks ar...
Barley; agronomic traits; disease resistance; elite; plant genetic resources; whole genome resequencing
null
null
null
null
null
39,930,924
Under the radar: How participating in a student organization can shape medical students' professional identity.
Medical education
Med Educ
59
7
10.1111/medu.15609
eng
2,025
7
null
2,025
2
10
[BACKGROUND] Medical students' professional identity formation (PIF) starts early in their academic journey and is shaped by diverse social influences. Research shows that while participation in student organizations cultivates essential skills, it may also reinforce homogeneity and prevent cultural change. However, th...
null
1.439
171
Education; Medicine
Medicine; Social Sciences
2,024
39,930,729
Evaluation of pharmacokinetic and pharmacodynamic similarity of an IDegAsp biosimilar versus the originator in healthy Chinese volunteers.
Expert opinion on investigational drugs
Expert Opin Investig Drugs
34
1-2
10.1080/13543784.2025.2463085
eng
2,025
null
null
2,025
2
11
[OBJECTIVES] 22011 is an insulin degludec/insulin aspart co-formulation (IDegAsp) that shares an identical amino acid sequence with Ryzodeg, the originator IDegAsp. This study aimed to compare the pharmacokinetics (PK), pharmacodynamics (PD), and safety of 22011 with Ryzodeg. [METHODS] In a single-center, randomized, o...
22011; Insulin biosimilar; euglycemic clamp study; insulin degludec/insulin aspart (IDegAsp); pharmacodynamics; pharmacokinetics
1.267
122
Medicine; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,930,713
Acute Administration of 10 mg Methylphenidate on Cognitive Performance and Visual Scanning in Healthy Adults: Randomised, Double-Blind, Placebo-Controlled Study.
Human psychopharmacology
Hum Psychopharmacol
40
2
10.1002/hup.70002
eng
2,025
3
null
null
null
null
[OBJECTIVE] To examine the effect of a low dose (10 mg) of methylphenidate on cognitive performance, visuospatial working memory (VSWM) and gaze behaviour capabilities in healthy adults. [METHODS] This randomised, double-blind, placebo-controlled and crossover study examined the effects of 10 mg methylphenidate on cogn...
null
0.51
87
Neurology; Neurology; Pharmacology; Psychiatry and Mental Health
Medicine; Neuroscience
2,024
39,930,575
The Bergen 4-day treatment for specific phobia of vomiting: a case series.
Behavioural and cognitive psychotherapy
Behav Cogn Psychother
53
2
10.1017/S135246582400050X
eng
2,025
6
null
2,025
2
11
[BACKGROUND] Specific phobia of vomiting (SPOV), also called emetophobia, is a debilitating condition that shares features with several other anxiety disorders and obsessive-compulsive disorder (OCD). Approximately half of sufferers from SPOV do not fully benefit from current treatment modalities. [AIMS] Bergen 4-day t...
Bergen 4-day treatment; case series; cognitive behavioural therapy; concentrated exposure therapy; emetophobia; specific phobia of vomiting
0.926
81
Medicine; Clinical Psychology
Medicine; Psychology
2,024
39,930,493
A systems based qualitative analysis exploring the potential to implement risk stratified bowel cancer screening in England.
BMC health services research
BMC Health Serv Res
25
1
10.1186/s12913-025-12381-w
eng
2,025
2
11
2,025
2
11
[BACKGROUND] Improving bowel cancer screening programmes through the introduction of risk stratification has been discussed, but not widely implemented in many countries. This study aimed to gain an understanding of system and programmatic aspects that need to be addressed to enable a move towards implementation. [METH...
Bowel cancer; Cancer screening; Health policy; Risk prediction; Risk stratification
1.174
157
Health Policy
Medicine
2,024
39,930,369
Development and characterization of small translocations between the Pm13 introgression from Aegilops longissima and wheat homoeologous A, B and D chromosomes.
BMC plant biology
BMC Plant Biol
25
1
10.1186/s12870-025-06167-9
eng
2,025
2
11
2,025
2
11
[BACKGROUND] Wild relatives have substantial impacts on the resistance of wheat to biotic and abiotic stresses. The genetic diversity of these wild varieties can be employed to widen the wheat gene pool by introducing wild allele introgression and genome structure variations. The powdery mildew resistance gene Pm13 was...
In situ hybridization; Pm13 introgression; ph1b mutation; Homoeologous recombination; Powdery mildew resistance
1.134
159
Plant Science
Agricultural and Biological Sciences
2,024
39,930,028
Awareness of human microbiome may promote healthier lifestyle and more positive environmental attitudes.
Communications medicine
Commun Med (Lond)
5
1
10.1038/s43856-025-00747-4
eng
2,025
2
10
2,025
2
10
[BACKGROUND] The human microbiome is an essential factor of physical and mental health, yet the general population has little knowledge about it. This survey explores public familiarity with the human microbiome and (potential) public preferences related to monitoring and improving one's microbiome health. The study al...
null
2.098
28
Assessment and Diagnosis; Epidemiology; Internal Medicine; Medicine; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,024
39,929,761
Cutoff levels of serum 25-OH-D for defining vitamin D deficiency in early infancy.
Pediatrics and neonatology
Pediatr Neonatol
null
null
10.1016/j.pedneo.2024.06.017
eng
2,025
1
23
2,025
1
23
[BACKGROUND] Various organizations use different thresholds to define vitamin D deficiency (VDD), which complicates its diagnosis, particularly in infants, as these thresholds are often extrapolated from adult data. Routine vitamin D3 supplementation in infants based on these criteria may impose unnecessary economic co...
25-Hydroxyvitamin D; Bone health; Cutoff level; Infants; Inflection point; Threshold value; Vitamin D deficiency
0.538
55
Pediatrics, Perinatology and Child Health
Medicine
2,024
39,929,736
Experiences of social prescribing in the UK: a qualitative systematic review.
The British journal of general practice : the journal of the Royal College of General Practitioners
Br J Gen Pract
75
752
10.3399/BJGP.2025.0179
eng
2,025
3
null
2,025
2
27
[BACKGROUND] Social prescribing connects patients to resources or activities to meet their non-medical needs. In the UK, it is often implemented in primary care. In the social prescribing pathway, patients are directed to link workers to identify suitable solutions for their needs such as art workshops or welfare benef...
general practice; link workers; mental health; qualitative research; social prescribing; systematic review
1.371
125
Family Practice; Medicine
Medicine
2,024
39,929,349
Serum exosomal miR-454-3p contributes to malignant progression of lung cancer by inhibiting HHEX.
Molecular and cellular probes
Mol Cell Probes
80
null
10.1016/j.mcp.2025.102019
eng
2,025
4
null
2,025
2
16
[BACKGROUND] Lung cancer is a common cancer. Exosomes are emerging mediators of intercellular communication, and miRNAs serve a crucial position in cancer progression. This project intends to discover whether exosomal miR-454-3p affects tumor progression and its underlying mechanisms. [METHODS] Exosomes were isolated u...
HHEX; Malignant progression; NSCLC; Serum exosomes; miR-454-3p
0.635
79
Cell Biology; Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,024
39,929,288
Assessing multiple MRI sequences in deep learning-based synthetic CT generation for MR-only radiation therapy of head and neck cancers.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Radiother Oncol
205
null
10.1016/j.radonc.2025.110782
eng
2,025
4
null
2,025
2
8
[PURPOSE] This study investigated the effect of multiple magnetic resonance (MR) sequences on the quality of deep-learning-based synthetic computed tomography (sCT) generation in the head and neck region. [MATERIALS AND METHODS] 12 MR series (T1pre-, T1post-contrast, T2 each with 4 Dixon images) were collected from 26 ...
Deep Learning; Head and Neck Cancers; Synthetic CT; U-Net
1.738
189
Hematology; Oncology; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
39,929,230
Weather-Related Pediatric Fatalities in the United States: 2001 to 2021.
Pediatrics
Pediatrics
null
null
10.1542/peds.2024-067567
eng
2,025
2
11
2,025
2
11
[BACKGROUND AND OBJECTIVES] Major weather and climate disasters are increasing in frequency and severity. How often these events result in child deaths is unknown. We assessed temporal and regional trends in pediatric fatalities due to weather events in the United States over the last 21 years. [METHODS] We conducted a...
null
2.406
409
Pediatrics, Perinatology and Child Health
Medicine
2,024
39,928,932
Machine Learning in the Management of Patients Undergoing Catheter Ablation for Atrial Fibrillation: Scoping Review.
Journal of medical Internet research
J Med Internet Res
27
null
10.2196/60888
eng
2,025
2
10
2,025
2
10
[BACKGROUND] Although catheter ablation (CA) is currently the most effective clinical treatment for atrial fibrillation, its variable therapeutic effects among different patients present numerous problems. Machine learning (ML) shows promising potential in optimizing the management and clinical outcomes of patients und...
atrial fibrillation; cardiac arrhythmia; catheter ablation; clinical intervention; deep learning; electrocardiogram; electronic health record; morbidity; mortality; patient management; prognosis; public health; quality assessment tools; quality of life; severe medical condition; thromboembolism
1.992
214
Health Informatics
Medicine
2,024
39,928,924
Perceptions and Experiences of Caregiver-Employees, Employers, and Health Care Professionals With Caregiver-Friendly Workplace Policy in Hong Kong: Thematic Analysis.
Interactive journal of medical research
Interact J Med Res
14
null
10.2196/58528
eng
2,025
2
10
2,025
2
10
[BACKGROUND] Caregiver-employees (CEs) for older adults experience a high burden to fulfill their dual roles. Caregiver-friendly workplace policy (CFWP) has been used in many countries to balance employment and caregiving duties, but it is a relatively new concept in Hong Kong. [OBJECTIVE] This study explored the views...
caregiver burden; caregiver employees; discrimination; dual roles; workplace
null
null
null
null
null
39,928,889
Usefulness of Semiautomated 3D Volumetric Assessment of Liver Tumor Burden for Patients With Unresectable Pancreatic Neuroendocrine Tumor: A Pilot Study.
Pancreas
Pancreas
54
2
10.1097/MPA.0000000000002413
eng
2,025
2
1
2,024
11
13
[OBJECTIVES] In patients with metastatic pancreatic neuroendocrine tumors (PanNETs), the Ki-67 index is objectively assessed by pathologists; however, liver tumor burden (LTB) depends on the subjective judgment of physicians. This study aimed to elucidate the usefulness of the semi-automated 3D volumetric assessment of...
null
0.747
123
Hepatology; Internal Medicine; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,928,635
Barriers and facilitators of adherence to treatment interventions for COPD amongst individuals from minority ethnic communities: Meta-ethnography.
PloS one
PLoS One
20
2
10.1371/journal.pone.0318709
eng
2,025
null
null
2,025
2
10
[OBJECTIVE] Numerous studies have documented the low adherence rate to treatment interventions for Chronic Obstructive Pulmonary Disease (COPD) amongst minority ethnic communities. This systematic meta-ethnographic review was performed to identify barriers and facilitators of adherence to treatment interventions (e.g.,...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
39,928,494
Feasibility and potential impact of a local proficiency testing program in Accra, Ghana.
American journal of clinical pathology
Am J Clin Pathol
163
6
10.1093/ajcp/aqaf007
eng
2,025
6
3
null
null
null
[OBJECTIVES] To implement a pilot proficiency testing (PT) program in Accra, Ghana, using locally produced PT materials and to explore the relationship between laboratory test costs and laboratory quality in Accra, Ghana. [METHODS] Remnant serum samples from a local laboratory were pooled, aliquoted, and distributed to...
Africa; accuracy; clinical chemistry; global health; quality
0.754
146
Pathology and Forensic Medicine; Medicine
Medicine
2,024
39,928,231
Bone marrow mesenchymal stem cells-derived exosomes deliver microRNA-142-3p to disturb glioma progression by down-regulating GFI1.
Discover oncology
Discov Oncol
16
1
10.1007/s12672-025-01837-4
eng
2,025
2
10
2,025
2
10
[OBJECTIVE] The mechanism of glioma development has been extensively explored and comprehension of the exosomal microRNA-142-3p/growth factor independent-1 (miR-142-3p/GFI1) axis in glioma is still at an initial stage. Therein, the conducted work goes toward ascertaining the role of the bone marrow mesenchymal stem cel...
Apoptosis; Exosomes; Glioma; Growth factor independent-1; Invasion; MicroRNA-142-3p; Migration; Proliferation
0.88
47
Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
39,927,927
Patient self-reported perception and knowledge of periodontal disease: An observational, university-representative, survey-based analysis in an academic setting.
Journal of the American Dental Association (1939)
J Am Dent Assoc
156
3
10.1016/j.adaj.2024.12.011
eng
2,025
3
null
2,025
2
8
[BACKGROUND] Limited information is available about patient knowledge and perceptions of periodontal diseases. In this observational, survey-based study, the authors investigated patients' understanding of periodontal diseases and their experience after periodontal therapy using self-reported oral health-related qualit...
Periodontal disease; dental health surveys; health-related quality of life; patient-reported outcome measures; treatment outcome
0.694
141
Dentistry; Medicine
Dentistry; Medicine
2,024
39,927,841
Exploring the Role of Self-Defective Beliefs in the Relation Between Sexual Orientation and Nonsuicidal Self-Injury in Young Women.
Suicide life-threatening behavior
Suicide Life Threat Behav
55
1
10.1111/sltb.13158
eng
2,025
2
null
null
null
null
[INTRODUCTION] People who identify as sexual minorities (SM) report higher rates of nonsuicidal self-injury (NSSI) than heterosexual individuals. One explanatory factor that may be important in this relation is self-defective beliefs. The present study examined the role of self-defective beliefs in the link between sex...
sexual minority
null
null
null
null
null
39,927,828
Suicidal Ideation, Planning, and Attempts Changes Among Diverse Canadian Public Safety Personnel After the Emotional Resilience Skills Training.
Suicide life-threatening behavior
Suicide Life Threat Behav
55
1
10.1111/sltb.13168
eng
2,025
2
null
null
null
null
[BACKGROUND] Public safety personnel (PSP) experience occupational stressors and potentially psychologically traumatic events, which increase the odds of screening positive for mental health disorders, and the risk of suicide. This study estimates suicidal ideation, planning, and attempts among Canadian PSP, and assess...
PTSI; firefighters; municipal police; paramedics; public safety communicators; suicidal thoughts and behaviors
null
null
null
null
null
39,927,516
Self-management interventions for quality of life in adults with visual impairment.
The Cochrane database of systematic reviews
Cochrane Database Syst Rev
2
2
10.1002/14651858.CD015790.pub2
eng
2,025
2
10
2,025
2
10
[RATIONALE] Visual impairment is a major health concern that predominantly impacts older adults due to age-related ocular diseases. Visual impairment affects more than 2200 million people worldwide and may lead to functional and psychological decline, emphasizing the need for effective self-management interventions. Se...
null
1.623
341
Medicine; Pharmacology
Medicine
2,024
39,927,496
Phototherapy in lymphoproliferative and inflammatory diseases associated with human T-lymphotropic virus.
Transactions of the Royal Society of Tropical Medicine and Hygiene
Trans R Soc Trop Med Hyg
119
7
10.1093/trstmh/traf009
eng
2,025
7
1
null
null
null
[BACKGROUND] Dermatological manifestations affect 5% of patients with human T-lymphotropic virus (HTLV). [METHODS] Thirteen patients with inflammatory or lymphoproliferative dermatological diseases, both HTLV-positive and HTLV-negative, were selected for treatment with ultraviolet B narrowband (UVB-NB) phototherapy. Cl...
human T-lymphotropic virus 1; lymphoproliferative disorders; phototherapy; virus diseases
0.644
120
Infectious Diseases; Medicine; Parasitology; Public Health, Environmental and Occupational Health
Immunology and Microbiology; Medicine
2,024
39,927,366
Molecular detection of Chlamydophila felis from conjunctiva of cats infected with conjunctivitis and upper respiratory disease.
Open veterinary journal
Open Vet J
14
12
10.5455/OVJ.2024.v14.i12.13
eng
2,024
12
null
2,024
12
31
[BACKGROUND] Chlamydiae are obligate generally Gram-negative intracellular parasites with bacterial characteristics, including a cell wall, DNA, and RNA, and the main characteristics of infections are ocular conjunctivitis and upper respiratory disease. [AIM] The aim of this study was to investigate the prevalence of C...
Co-infection; Feline chlamydophilasis; PCR; Shelter cats; URTI
0.362
22
Veterinary
Veterinary
2,024
39,927,284
Time to dietary diversity of complementary feeding improvements and its associated factors among infants aged 6-12 months in Ethiopia: evidence from performance monitoring for action.
Frontiers in nutrition
Front Nutr
12
null
10.3389/fnut.2025.1451193
eng
2,025
null
null
2,025
1
24
[BACKGROUND] Infant and Young Child Feeding significantly affect the health, development, and nutritional status of children under 2 years old, ultimately affecting their survival. The aim of this study is to determine the time to improvement in dietary diversity and associated factors in infants aged 6 to 12 months. [...
Ethiopia; dietary diversity; improvements; infants; women
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
39,927,232
Combining preoperative expectations and postoperative met expectations to predict patient-reported outcomes after knee surgery.
Journal of orthopaedics
J Orthop
67
null
10.1016/j.jor.2025.01.024
eng
2,025
9
null
2,025
1
17
[INTRODUCTION] Both preoperative expectations and postoperative met expectations can independently influence patient-reported outcomes (PROs), however, their combined effect on PROs is not well understood. This study aimed to determine the prognostic significance of categorizing non-arthroplasty knee surgery patients i...
Cluster analysis; Expectations; Knee surgery; PROMIS; Patient-reported outcomes
0.67
41
Orthopedics and Sports Medicine
Medicine
2,024
39,927,221
A comparison between adjuvant and delivering functions of iron oxide and calcium phosphate nanoparticles, using a model protein against Brucella melitensis.
Clinical and experimental vaccine research
Clin Exp Vaccine Res
14
1
10.7774/cevr.2025.14.e3
eng
2,025
1
null
2,025
1
13
[PURPOSE] Calcium phosphate (CaP) and iron oxide (IO) nanoparticles (NPs) are promising adjuvants and delivery systems for vaccination. Furthermore, it has been shown that the chimeric antigen TF/Bp26/Omp31 (TBO) is a good candidate for stimulating protection against virulent Brucella melitensis. Our aim in the present...
Brucellosis; Calcium phosphate; Iron oxide; Nanoparticles
0.358
21
Infectious Diseases; Pharmacology; Public Health, Environmental and Occupational Health; Immunology and Allergy
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,927,008
Comparative Study of Periodontal Health in Patients with Fixed Braces Versus Clear Aligners.
Journal of pharmacy bioallied sciences
J Pharm Bioallied Sci
16
Suppl 4
10.4103/jpbs.jpbs_993_24
eng
2,024
12
null
2,024
11
21
[BACKGROUND] Orthodontic therapy is often used to cure dental malocclusions; however, since orthodontic equipment is difficult to keep clean, it might have an adverse effect on periodontal health. Clear aligners and fixed braces are two common orthodontic treatments. [MATERIALS AND METHODS] In this research, 100 patien...
Clear aligners; fixed braces; gingival index; orthodontics; periodontal health; plaque index; probing depth
null
null
null
null
null
39,926,889
Evaluating the Shear Bond Strength of Repaired Composites Using Different Surface Treatments and Repair Materials: An In-Vitro Comparative Study.
Journal of pharmacy bioallied sciences
J Pharm Bioallied Sci
16
Suppl 4
10.4103/jpbs.jpbs_956_24
eng
2,024
12
null
2,024
12
5
[INTRODUCTION] Composite resin is commonly used in dental restorations, though it is prone to degradation over time. Repairing these restorations is often preferable for issues such as discoloration, small areas of decay near the restoration margin, or for preserving tooth health without the need for complete removal. ...
3M ESPE Single Bond Universal adhesive; Ivoclar Tetric N-bond; aluminum oxide air-abrasion; composite resin; dental restorations; diamond bur abrasion; fracture analysis; shear bond strength; surface treatment; thermal cycling
null
null
null
null
null
39,926,812
Study of Severe Preeclampsia: Epidemiological, Diagnostic, Therapeutic, and Prognostic Aspects over One Year at SMGS Hospital, Jammu: A Retrospective Study.
Journal of pharmacy bioallied sciences
J Pharm Bioallied Sci
16
Suppl 4
10.4103/jpbs.jpbs_859_24
eng
2,024
12
null
2,024
11
23
[BACKGROUND] This research was conducted retrospectively, with a focus on description and analysis, spanning from July 2022 to June 2023. [MATERIALS AND METHODS] The research included all pregnant women who were hospitalized to the department and delivered with a gestational age of more than 22 weeks and had severe pre...
Diagnostic; epidemiological; severe pre-eclampsia; therapeutic
null
null
null
null
null
39,926,755
Assessment of the Hardness of Various Orthodontic Wires.
Journal of pharmacy bioallied sciences
J Pharm Bioallied Sci
16
Suppl 4
10.4103/jpbs.jpbs_776_24
eng
2,024
12
null
2,024
11
13
[INTRODUCTION] The mechanical characteristics of orthodontic wires are crucial since they have a significant impact on the effectiveness of orthodontic therapy, and patients undergoing orthodontic treatment are becoming more and more picky about their aesthetic preferences. [OBJECTIVES] The goal of the current investig...
Microhardness; orthodontic; stainless; steel
null
null
null
null
null
39,926,727
Comparative Evaluation of Microleakage and Compressive Strength of Different Restorative Materials - An in vitro Study.
Journal of pharmacy bioallied sciences
J Pharm Bioallied Sci
16
Suppl 4
10.4103/jpbs.jpbs_1174_24
eng
2,024
12
null
2,024
11
27
[BACKGROUND] For dental restorations to be successful in clinical practice, they must possess excellent mechanical properties, such as high compressive strength and microleakage resistance. [MATERIALS AND METHODS] A total of 80 Class V cavities were prepared from extracted human teeth, divided into four groups of 20 (G...
Bulk-fill composites; Zirconomer; compressive strength; glass ionomer cement; microleakage; sphere TEC fillers
null
null
null
null
null
39,926,603
Single-cell sequencing uncovers the mechanistic role of DAPK1 in glioma and its diagnostic and prognostic implications.
Frontiers in immunology
Front Immunol
15
null
10.3389/fimmu.2024.1463747
eng
2,024
null
null
2,025
1
24
[BACKGROUND] We conducted an investigation into the characteristics of single-cell differentiation data in gliomas, with a focus on developing DAPK1-based prognostic markers to predict patient outcomes. Dysregulated expression of DAPK1 has been associated with the invasive behavior of various malignancies, including gl...
DAPK1; diagnosis; glioma; immune infiltration; prognosis; tumor immune microenvironment
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
39,926,272
Blood hemoglobin levels of the general population residing at low range altitudes.
Annals of clinical epidemiology
Ann Clin Epidemiol
7
1
10.37737/ace.25002
eng
2,025
1
1
2,024
10
31
[BACKGROUND] Polycythemia often develops in the highland areas. However, it remains to be clarified whether blood hemoglobin levels in the general population are affected by elevations above sea level of 1,000 m. [METHODS] This ecological study targeting secondary medical areas in Japan considered residential altitude ...
Anemia; altitude; hemoglobin; hypoxia
null
null
null
null
null
39,926,204
A Systematic Review and Meta-Analysis: Adverse Inflammatory Bowel Disease Outcomes Following Acute COVID-19.
Gastro hep advances
Gastro Hep Adv
4
3
10.1016/j.gastha.2024.10.021
eng
2,025
null
null
2,024
10
24
[BACKGROUND AND AIMS] Respiratory viral infections have been implicated in the exacerbation of immune-mediated inflammatory diseases such as inflammatory bowel disease (IBD). To understand the impact of early SARS-CoV-2 variants on the risk of adverse IBD outcomes, we aimed to perform a meta-analysis of high-quality st...
COVID-19 Infection; IBD Flares; Inflammatory Bowel Disease (IBD)
0.537
9
Medicine; Gastroenterology; Hepatology
Medicine
2,024
39,926,164
Automating pharmacovigilance evidence generation: using large language models to produce context-aware structured query language.
JAMIA open
JAMIA Open
8
1
10.1093/jamiaopen/ooaf003
eng
2,025
2
null
2,025
2
8
[OBJECTIVE] To enhance the accuracy of information retrieval from pharmacovigilance (PV) databases by employing Large Language Models (LLMs) to convert natural language queries (NLQs) into Structured Query Language (SQL) queries, leveraging a business context document. [MATERIALS AND METHODS] We utilized OpenAI's GPT-4...
drug safety; information retrieval; large language models (LLMs); natural language processing (NLP); pharmacovigilance
1.085
32
Health Informatics
Medicine
2,024
39,926,026
Prevalence and Clinical Correlation of Cardiometabolic Risk Factors in Alcohol-Related Liver Disease and Metabolic Dysfunction and Alcohol Associated Liver Disease (MetALD).
Journal of clinical and experimental hepatology
J Clin Exp Hepatol
15
3
10.1016/j.jceh.2024.102492
eng
2,025
null
null
2,024
12
19
[BACKGROUND] Recent introduction of new steatotic liver disease categorizations has necessitated updated epidemiologic studies. Specifically, recognition of (1) "MetALD" defined as where metabolic dysfunction-associated steatotic liver disease (MASLD) overlaps with alcohol use and (2) alcohol-related liver disease (ALD...
MetALD; alcoholic liver disease; epidemiology; metabolic syndrome
0.994
54
Hepatology
Medicine
2,024
39,925,930
Angesinenolide B, A Phthalide Dimeric Peroxide, Exerts Anti-Inflammatory Properties by Suppressing MAPK/STATs Signaling Pathways and ROS Production.
Journal of inflammation research
J Inflamm Res
18
null
10.2147/JIR.S501313
eng
2,025
null
null
2,025
2
3
[PURPOSE] Angesinenolide B (ASB), a phthalide dimer with a peroxy bridge, is uniquely isolated from Chinese medicine Angelica sinensis radix and demonstrates significant anti-inflammatory properties. The objective of the current study was to evaluate the anti-inflammatory function of ASB and the potential mechanism in ...
Angesinenolide B; ROS; anti-inflammation; cytokine; signaling pathway
1.14
58
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
39,925,806
Immune checkpoint inhibitor-induced diabetes mellitus: clinical characteristics and risk factors.
Frontiers in immunology
Front Immunol
16
null
10.3389/fimmu.2025.1499074
eng
2,025
null
null
2,025
1
24
[BACKGROUND] Emerging evidence indicates that immune checkpoint inhibitor-induced diabetes mellitus (ICI-DM) might be more common than initially reported, and more different clinical pictures associated with ICI-DM were described. [OBJECTIVE] The aim of our study was to identify the clinical characteristics and possibl...
cancer; diabetes mellitus; immune checkpoint inhibitors; immune-related adverse events; immunotherapy
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
39,924,478
Phenotypic and genotypic insights into concurrent tertiary trisomy for 9p and 18p.
Molecular cytogenetics
Mol Cytogenet
18
1
10.1186/s13039-025-00704-9
eng
2,025
2
10
2,025
2
10
[BACKGROUND] Carriers of balanced reciprocal translocation are usually phenotypically normal; however, they have an increased risk of producing gametes with chromosomal imbalance through different types of meiotic segregation of the translocation quadrivalent. The genetically imbalanced gametes when they survive can re...
CMA anlysis; Concurrent trisomy 9p and 18p; Familial t(9;18)(q13;p11.2)
null
null
null
null
null
39,924,466
Development of machine learning prognostic models for overall survival of epithelial ovarian cancer patients: a SEER-based study.
Expert review of anticancer therapy
Expert Rev Anticancer Ther
null
null
10.1080/14737140.2025.2465903
eng
2,025
2
16
2,025
2
16
[RESEARCH DESIGN AND METHODS] Data were obtained from the SEER database for women diagnosed with EOC between 2004 and 2020. Clinical features, treatment regimens and overall survival (OS) were analyzed. Cox regression was conducted to identify prognostic factors associated with EOC. We employed 5-fold cross-validation ...
Epithelial ovarian cancer; SEER database; machine learning; prognosis; survival
0.926
88
Oncology; Pharmacology
Medicine
2,024
39,924,248
Association Between Alcohol Consumption and the Risk of Type 2 Diabetes Mellitus Across Different Body Mass Index Categories Among Japanese Workers.
Journal of epidemiology
J Epidemiol
35
8
10.2188/jea.JE20240259
eng
2,025
8
5
2,025
6
18
[BACKGROUND] While evidence from Western countries links low-to-moderate alcohol consumption to a lower risk of type 2 diabetes mellitus (T2D), findings have been inconsistent in Asia. Since T2D in Asia involves both insulin resistance and deficient insulin secretion, both of which are differently affected by alcohol, ...
alcohol consumption; body mass index; type 2 diabetes mellitus
1.254
95
Epidemiology; Medicine
Medicine
2,024
39,923,847
Citrulline Inhibits Clostridioides difficile Infection With Anti-inflammatory Effects.
Cellular and molecular gastroenterology and hepatology
Cell Mol Gastroenterol Hepatol
19
6
10.1016/j.jcmgh.2025.101474
eng
2,025
null
null
2,025
2
7
[BACKGROUND AND AIMS] Clostridioides difficile infection (CDI) causes colitis and diarrhea. C. difficile bacterium produces toxins A and B, which cause intestinal inflammation. A metabolomics analysis discovered fecal metabolites with anti-inflammatory effects in CDI. We aimed to identify an anti-CDI metabolite that ca...
Inflammation; Metabolite; Microbiome
3.069
75
Gastroenterology; Hepatology
Medicine
2,024
39,923,803
Using Parks and Recreation Providers to Enhance Obesity Treatment: A Randomized Controlled Trial.
Pediatrics
Pediatrics
null
null
10.1542/peds.2024-068427
eng
2,025
2
10
2,025
2
10
[OBJECTIVE] Intensive health behavior and lifestyle treatment (IHBLT) is recommended for children aged 6-18 years with obesity. The objective was to evaluate the effectiveness of Fit Together, a health care and parks and recreation partnership to deliver IHBLT. [METHODS] A randomized controlled trial was conducted from...
null
2.406
409
Pediatrics, Perinatology and Child Health
Medicine
2,024
39,923,705
Research status of traditional complementary medicine systems across the world.
Journal of Ayurveda and integrative medicine
J Ayurveda Integr Med
16
2
10.1016/j.jaim.2024.101078
eng
2,025
null
null
2,025
2
8
[BACKGROUND] Despite strong presence of biomedicine, traditional and complementary medicine (T CM) systems have sustained with their multidimensional connect with people. However, their scientific acceptance and mainstreaming falls short due to inadequacies in research. Also, available reports in this regard scarcely ...
Ayurveda; Conventional medicine; Research translation; TCM; Traditional medicine
0.373
42
Complementary and Alternative Medicine; Drug Discovery
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
39,923,646
Role of Tau and Amyloid-beta in autophagy gene dysregulation through oxidative stress.
Tissue cell
Tissue Cell
93
null
10.1016/j.tice.2025.102765
eng
2,025
4
null
2,025
1
28
[BACKGROUND] Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by memory impairment and cognitive decline. Our previous research has demonstrated that pathological Tau and Amyloid-beta (Aβ) disrupt autophagy gene expression, independently. Other studies have shown that these pathological ...
Alzheimer's disease; Amyloid beta; Autophagy; Drosophila melanogaster; Tau; Thymoquinone
null
null
null
null
null
39,923,314
Quantitative imaging using [[18]F]F-TZ3108 to assess metabolic-associated fatty liver disease progression and low-carbohydrate diet efficacy.
Nuclear medicine and biology
Nucl Med Biol
144-145
null
10.1016/j.nucmedbio.2025.108997
eng
2,025
null
null
2,025
1
22
[OBJECTIVE] The Sigma-1 receptor (Sig-1R), located in the mitochondrion-associated membranes (MAMs), is an important biomarker for endoplasmic reticulum (ER) stress and plays a crucial role in the advancement of metabolic-associated fatty liver disease (MAFLD). Despite its significance, current methods to monitor MAFLD...
null
0.742
100
Radiology, Nuclear Medicine and Imaging; Cancer Research; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,923,299
Different IL-1β levels differentially mediate neuroprotection or neurodegeneration and may be related to BDNF.
Cytokine
Cytokine
188
null
10.1016/j.cyto.2025.156877
eng
2,025
4
null
2,025
2
8
[BACKGROUND] The detrimental and protective effects of interleukin 1β (IL-1β) have been reported. We have previously shown that the periods of IL-1β elevation is related to its dual effects. However, the effects of different IL-1β concentrations on neuropathological processes are unclear. Studies have demonstrated that...
BDNF; Neuroinflammation
1.108
142
Biochemistry; Hematology; Immunology; Immunology and Allergy; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,024
39,923,275
Characterizing uveal melanoma patients with peritoneal metastases: A retrospective single-center analysis.
European journal of cancer (Oxford, England : 1990)
Eur J Cancer
218
null
10.1016/j.ejca.2025.115280
eng
2,025
3
11
2,025
2
6
[BACKGROUND] Metastatic uveal melanoma (mUM) is an aggressive cancer predominately affecting the liver. Peritoneal metastases (PM) occur rarely, and there is limited knowledge about this subgroup´s clinical course and biology. [METHODS] We analyzed 41 mUM patients with confirmed PM from the Charité-Universitätsmedizin ...
BAP1; Checkpoint inhibitors; Monosomy; Peritoneal metastases; Prognosis; Survival; Uveal melanoma
2.691
256
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
39,923,263
Surgical Outcomes of Radical Nephrectomy and Inferior Vena Cava Thrombectomy Following Preoperative Systemic Immunotherapy: A Propensity Score Analysis.
Clinical genitourinary cancer
Clin Genitourin Cancer
23
2
10.1016/j.clgc.2025.102307
eng
2,025
4
null
2,025
1
21
[INTRODUCTION] The impact of neoadjuvant immune checkpoint inhibitors (ICIs) on perioperative outcomes of radical nephrectomy (RN) with inferior vena cava (IVC) thrombectomy for renal cell carcinoma (RCC) remains unclear. This study aimed to assess the safety of preoperative immunotherapy prior to surgical resection of...
Immune checkpoint inhibitors; Kidney cancer; Peri-operative outcomes; Renal cell carcinoma; Tumour thrombectomy
1.13
59
Urology; Oncology
Medicine
2,024
39,923,174
Health-Seeking Behavior and Community Perception of Chhaupadi Practices.
Journal of Nepal Health Research Council
J Nepal Health Res Counc
22
3
10.33314/jnhrc.v22i03.5280
eng
2,024
12
20
2,024
12
20
[BACKGROUND] The Chhaupadi system, mainly in the Western part of Nepal, forces women and girls to stay in huts or cowsheds during menstruation, barring them from their homes. This study aims to analyze the health-seeking behavior and community perception of Chhaupadi practices and examine their relationship with ecolog...
Chhaupadi; ethnography; inclusion; sinful.
0.266
23
Medicine
Medicine
2,024
39,922,761
Effects of duration of high-fat diet on adipocyte hyperplasia in rat epididymis.
Obesity research clinical practice
Obes Res Clin Pract
19
1
10.1016/j.orcp.2025.02.001
eng
2,025
null
null
2,025
2
7
[BACKGROUND] High-fat diet (HFD) contributes to obesity and enhances the expression of mature adipocyte markers. However, the effect of HFD on adipocyte hyperplasia remains controversial. This may be due to variations in the duration of HFD. This study aimed to investigate the effects of different durations of HFD on a...
Adipocyte hyperplasia; Adiponectin; Obesity process; Perilipin-A
null
null
null
null
null
39,922,746
Clinical behavior and survival of CAD-CAM resin nanoceramic and polymer interpenetrating ceramic network material restorations on endodontically treated teeth: A systematic review and meta-analysis.
The Journal of prosthetic dentistry
J Prosthet Dent
133
6
10.1016/j.prosdent.2025.01.019
eng
2,025
6
null
2,025
2
7
[STATEMENT OF PROBLEM] Attempting to combine the mechanical and optical properties of ceramics and composite resins to mimic natural teeth has led to the emergence of resin nanoceramics and polymer interpenetrating ceramic network materials. Systematic reviews on the survival of these materials in endodontically treate...
null
1.263
160
Medicine; Oral Surgery
Dentistry; Medicine
2,024
39,922,565
Gastrointestinal symptoms and bowel habits in 53 046 healthy Danish blood donors: a nationwide cross-sectional study.
BMJ open gastroenterology
BMJ Open Gastroenterol
12
1
10.1136/bmjgast-2024-001518
eng
2,025
2
8
2,025
2
8
[OBJECTIVE] To characterise gastrointestinal symptoms and bowel habits in healthy blood donors and explore symptom phenotypes and their associated factors. [METHODS] Between November 2020 and March 2023, 53 046 participants in the nationwide Danish Blood Donor Study completed a questionnaire including 13 gastrointestin...
EPIDEMIOLOGY; FUNCTIONAL BOWEL DISORDER; GASTROINTESTINAL FUNCTION; IRRITABLE BOWEL SYNDROME
1.166
39
Gastroenterology
Medicine
2,024
39,922,557
Impact of amyloidosis on outcomes after transcatheter aortic valve implantation.
Revista espanola de cardiologia (English ed.)
Rev Esp Cardiol (Engl Ed)
null
null
10.1016/j.rec.2025.01.012
eng
2,025
2
6
2,025
2
6
[INTRODUCTION AND OBJECTIVES] Data on the impact of amyloidosis on outcomes after transcatheter aortic valve implantation (TAVI) are limited. The objective of this study was to evaluate the 1-year risk of adverse events post-TAVI in patients with amyloidosis. [METHODS] Patients undergoing TAVI (between 2005 and 2023) w...
Amiloidosis; Amyloidosis; Complicaciones; Complications; Outcomes; Resultados; TAVI
0.569
80
Cardiology and Cardiovascular Medicine
Medicine
2,024
39,922,444
Body image and sexual function improve following prolapse repair.
American journal of obstetrics and gynecology
Am J Obstet Gynecol
null
null
10.1016/j.ajog.2025.01.042
eng
2,025
2
6
2,025
2
6
[BACKGROUND] Body image (a woman's perceptions and attitudes about her body) likely plays a role in pelvic organ prolapse treatment satisfaction and postoperative sexual function. [OBJECTIVE] The primary aim of this study was to describe changes in body image after surgical repair of vaginal vault prolapse. The seconda...
body image; prolapse surgery; sexual function
2.772
274
Obstetrics and Gynecology
Medicine
2,024
39,922,381
Stellate Nonhereditary Idiopathic Foveomacular Retinoschisis and Central Anomalous Retinoschisis with mid-PEripheral Traction.
Ophthalmology. Retina
Ophthalmol Retina
9
8
10.1016/j.oret.2025.01.019
eng
2,025
8
null
2,025
2
6
[PURPOSE] To report the clinical and multimodal imaging (MMI) findings and long-term follow-up of stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR) contiguous with midperipheral retinoschisis (MPRS) and to describe a severe SNIFR variant termed CARPET (Central Anomalous Retinoschisis with mid-PEriphe...
CARPET; OCT; Peripheral retinoschisis; SNIFR
1.982
53
Ophthalmology
Medicine
2,024
39,922,296
Current Practices in Fertility-Based Counseling Among Individuals With Turner Syndrome: A Retrospective Study.
Journal of pediatric and adolescent gynecology
J Pediatr Adolesc Gynecol
38
4
10.1016/j.jpag.2025.02.002
eng
2,025
8
null
2,025
2
6
[STUDY OBJECTIVE] To evaluate current practices and examine patient and provider characteristics associated with delivery of fertility-based counseling and pursuit of autologous oocyte cryopreservation or embryo cryopreservation among individuals with Turner syndrome (TS) at a large academic institution. [METHODS] A re...
Assisted reproduction; Fertility preservation; Mosaic Turner syndrome; Primary ovarian insufficiency; Turner syndrome
0.683
73
Medicine; Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,024
39,922,177
Clinical outcomes of repaired radial meniscal tears: A retrospective study with minimum 2-year follow-up.
The Knee
Knee
53
null
10.1016/j.knee.2025.01.009
eng
2,025
3
null
2,025
2
7
[BACKGROUND] The management of meniscal radial tears has changed significantly in recent years in favor of meniscus repair. However, there is still limited published data on the outcomes and risk factors associated with repair failure. The objective of this study is to evaluate the clinical success rate of repaired men...
Meniscal healing rate; Meniscal repair; Radial tear; Risk factor
0.821
98
Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,024