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40,079,423
Trends in diabetes-related foot disease in a tertiary health service in Australia: a 10-year retrospective study.
Internal medicine journal
Intern Med J
55
5
10.1111/imj.70036
eng
2,025
5
null
2,025
3
13
[BACKGROUND AND AIMS] Despite being a major cause of hospitalisations, there is limited literature on the trends in diabetes-related foot disease (DFD) in Victoria, Australia. The aim of this study was to assess the incidence of DFD admissions and outcomes in inpatients with DM at a major Victorian health service. [MET...
amputation; diabetes mellitus; foot ulcer; hospitalisations
0.584
85
Internal Medicine
Medicine
2,024
40,079,312
Persistent Beta-Blocker Therapy Reduces Long-Term Mortality in Patients With Acute Ischemic Stroke With Elevated Heart Rates.
Journal of the American Heart Association
J Am Heart Assoc
14
6
10.1161/JAHA.124.039678
eng
2,025
3
18
2,025
3
13
[BACKGROUND] Elevated heart rate in patients with acute ischemic stroke is associated with increased risk of mortality. Beta-blocker therapy is well known to reduce heart rate. [METHODS AND RESULTS] This study was a post hoc analysis of patients with acute ischemic stroke with maximum heart rates ≥100 bpm. Beta-blocker...
beta blocker; heart rate; ischemic stroke
2.189
152
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,079,213
A 10-year examination of people with psychosis in American television programing: are representations improving over time?
Journal of mental health (Abingdon, England)
J Ment Health
null
null
10.1080/09638237.2025.2478371
eng
2,025
3
13
2,025
3
13
[BACKGROUND] Media portrayals inform understandings of mental illness; yet little research has investigated representations of characters with psychosis in fictional television programming. [AIMS] This study examined the valence and trends regarding representations of people with psychosis in popular fictional televisi...
content analysis; media; mental illness; psychotic disorders; social stigma
1.212
88
Medicine; Psychiatry and Mental Health
Medicine
2,024
40,078,589
Predictive value of early neutrophil-to-lymphocyte ratio and C-reactive protein in pediatric steroid-sensitive nephrotic syndrome.
Frontiers in nephrology
Front Nephrol
5
null
10.3389/fneph.2025.1524231
eng
2,025
null
null
2,025
2
14
[OBJECTIVE] This study aims to investigate the predictive value of early neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP) levels for relapse and adverse prognosis within one year in children diagnosed with steroid-sensitive nephrotic syndrome (SSNS). [METHODS] This study included a total of 145 pediatr...
CRP; NLR; adverse prognosis; pediatric steroid-sensitive nephrotic syndrome; relapse
null
null
null
null
null
40,078,459
The role of HDAC2 inhibition in cardioprotection against doxorubicin-induced myocardial injury.
Frontiers in cardiovascular medicine
Front Cardiovasc Med
12
null
10.3389/fcvm.2025.1557119
eng
2,025
null
null
2,025
2
26
[INTRODUCTION] The molecular mechanisms underlying cardioprotection against doxorubicin (DOX)-induced myocardial injury are poorly understood. Histone deacetylase 2 (HDAC2) plays a significant role in oxidative stress, apoptosis, and mitochondrial dysfunction and is implicated in many human diseases, This study investi...
HDAC2; PI3K/AKT; apoptosis; cardiac function; doxorubicin
0.975
81
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,078,392
Person-centered workplace culture: insights from an inpatient department for older adults with chronic illnesses.
Frontiers in medicine
Front Med (Lausanne)
12
null
10.3389/fmed.2025.1532419
eng
2,025
null
null
2,025
2
26
[INTRODUCTION] An aging population and the increasing prevalence of chronic conditions challenge healthcare systems in developed countries. In response, there is a growing emphasis on person-centered care, as advocated by the World Health Organization and integrated into national health strategies in countries such as ...
aged; inpatient; non-communicable diseases; patient-centered care; workplace cultural critical assessment tool; workplace culture
0.962
102
Medicine
Medicine
2,024
40,078,187
Prognostic impact of initial platelet count and post-induction platelet recovery in elderly AML patients: associated with circulating cytokines.
Frontiers in oncology
Front Oncol
15
null
10.3389/fonc.2025.1534158
eng
2,025
null
null
2,025
2
26
[OBJECTIVE] Acute myeloid leukemia (AML) is a highly heterogeneous hematologic malignancy, with various clinical features influencing its prognosis. The aim of this study to evaluate the impact of platelet count at diagnosis and platelet recovery after induction chemotherapy on the survival outcomes of elderly AML pati...
acute myeloid leukemia; circulating cytokines; geriatric; platelets; prognostic
1.075
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,078,095
Quantifying the sources of discrepancy between total recording time and total sleep time in home sleep apnea testing: insights from home-based polysomnography.
Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
J Clin Sleep Med
21
6
10.5664/jcsm.11632
eng
2,025
6
1
null
null
null
[STUDY OBJECTIVES] To quantify the contribution of sleep onset latency (SOL), wake after sleep onset (WASO), and wake after sleep offset (WASF) to the discrepancy between total recording time (TRT) and total sleep time (TST) in home-based polysomnography (PSG) using patient-activated and deactivated monitoring devices....
HSAT; TRT; TST; WASF; apnea-hypopnea index; home PSG; home sleep apnea testing; home sleep study; type 2 sleep study; type 3 sleep study
1.12
129
Neurology; Neurology; Pulmonary and Respiratory Medicine
Medicine; Neuroscience
2,024
40,077,939
Online Education on Sustainable Nutrition Affects Women's Sustainable Eating Behavior and Anthropometric Measures.
Public health nursing (Boston, Mass.)
Public Health Nurs
42
3
10.1111/phn.13548
eng
2,025
null
null
2,025
3
12
[OBJECTIVE] To determine the effect of online sustainable nutrition education (SNE) on sustainable eating behaviors and anthropometric measurements in women. [DESIGN] In the research, a pretest-posttest quasi-experimental design was used for groups that were subjected to two different trainings. [SAMPLE] In the educati...
anthropometric measurements; healthy eating behaviors; obesity; online nutrition education; sustainable eating behaviors
0.723
63
Nursing; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,024
40,075,619
Radiomics in Dermatological Optical Coherence Tomography (OCT): Feature Repeatability, Reproducibility, and Integration into Diagnostic Models in a Prospective Study.
Cancers
Cancers (Basel)
17
5
10.3390/cancers17050768
eng
2,025
2
24
2,025
2
24
[BACKGROUND/OBJECTIVES] Radiomics has seen substantial growth in medical imaging; however, its potential in optical coherence tomography (OCT) has not been widely explored. We systematically evaluate the repeatability and reproducibility of handcrafted radiomics features (HRFs) from OCT scans of benign nevi and examine...
OCT; artificial intelligence; radiomics
1.462
157
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,075,529
Self-Compassion and Medical Coping Modes of Patients With Rheumatoid Arthritis: Mediating Role of Personal Mastery.
Musculoskeletal care
Musculoskeletal Care
23
1
10.1002/msc.70074
eng
2,025
3
null
null
null
null
[AIM] To test the mediating role of personal mastery in the relationship between self-compassion and medical coping modes in patients with rheumatoid arthritis (RA). [DESIGN] A cross-sectional questionnaire survey was administered. [METHODS] We enrolled a convenience sampling of patients with RA from a Class A tertiary...
coping strategies; personal mastery; rheumatoid arthritis; structural equation model
0.6
38
Chiropractics; Nursing; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Rheumatology
Health Professions; Medicine; Nursing
2,024
40,075,457
Establishment and application of a wild neonatal mouse model infected with an Echovirus 30 isolate.
Virology journal
Virol J
22
1
10.1186/s12985-025-02684-z
eng
2,025
3
12
2,025
3
12
[BACKGROUND] Echovirus 30 (E30) is a significant pathogen associated with various illnesses such as viral meningitis, viral myocarditis. Currently, there are no specific drugs or vaccines targeting this virus. An appropriate animal model is imperative for assessing drug and vaccine efficacy. [METHODS] This investigatio...
Antiviral drugs; Echovirus 30; Neonatal murine model; Viral meningitis
0.992
104
Infectious Diseases; Virology
Immunology and Microbiology; Medicine
2,024
40,075,433
Changes of perioperative cognitive function and its effect on quality of life in laryngeal cancer.
Perioperative medicine (London, England)
Perioper Med (Lond)
14
1
10.1186/s13741-025-00507-x
eng
2,025
3
13
2,025
3
13
[BACKGROUND] Few studies have been published on the cognitive function and its relationship with quality of life (QoL) in patients with laryngeal squamous cell carcinoma (LSCC) undergoing surgery. [OBJECTIVE] This study aimed to assess the association between changes in cognitive function perioperatively with QoL among...
Cancer-related cognitive impairment; Operation; Perioperative period; Quality of life; Squamous cell carcinoma of the larynx
null
null
null
null
null
40,075,427
Acid-responsive aggregated carrot-derived nanoantioxidants alleviate oxidative stress and restore osteoblast activity.
Journal of nanobiotechnology
J Nanobiotechnology
23
1
10.1186/s12951-025-03235-y
eng
2,025
3
12
2,025
3
12
[BACKGROUND] Excessive generation of reactive oxygen species is a hallmark of the osteoporotic bone microenvironment, which leads to the damage of mitochondrial function and the deactivation of osteoblasts. Fruits and vegetables are rich sources of antioxidants, which play a key role in scavenging free radicals and mai...
Acid-triggered aggregation; Carrot-derived nanoantioxidants; Osteoporosis therapy; Passive targeting to bone tissue; Restoration of mitochondrial function; Restore osteoblast activity
2.282
125
Applied Microbiology and Biotechnology; Bioengineering; Biomedical Engineering; Medicine; Molecular Medicine; Nanoscience and Nanotechnology; Pharmaceutical Science
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Engineering; Immunology and Microbiology; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,075,391
Comparative analysis of myopia correction outcomes and aberration changes between PRK and SMILE: A study based on strict refractive criteria.
BMC ophthalmology
BMC Ophthalmol
25
1
10.1186/s12886-025-03943-x
eng
2,025
3
12
2,025
3
12
[PURPOSE] To analyze the refractive outcomes and changes in corneal aberrations after PRK and SMILE surgeries, and to compare these two methods. [PATIENTS AND METHODS] This retrospective comparative study investigated patients aged 20-40 years who underwent SMILE or PRK for the correction of myopia between - 1.00 D and...
Corneal aberrations; Low myopia; PRK; Refractive surgery; SMILE
0.72
67
Medicine; Ophthalmology
Medicine
2,024
40,075,258
Expression variation of Viola APETALA3 orthologous genes is correlated with chasmogamous and cleistogamous flower development.
BMC plant biology
BMC Plant Biol
25
1
10.1186/s12870-025-06348-6
eng
2,025
3
12
2,025
3
12
[BACKGROUND] Viola philippica and V. prionantha develop chasmogamous (CH) flowers under ≤ 12-h daylight conditions and cleistogamous (CL) flowers under long daylight ( 12-h daylight) conditions (LD), whereas V. cornuta develops CH flowers regardless of the daylight conditions. APETALA3 (AP3) is a major floral B-functio...
APETALA3; Viola; Chasmogamous flower; Cleistogamy; Differential expression; Photoperiod
1.134
159
Plant Science
Agricultural and Biological Sciences
2,024
40,074,630
Health literacy in adults with a spinal cord injury or disorder: An updated and expanded systematic review.
Disability and health journal
Disabil Health J
18
3
10.1016/j.dhjo.2025.101821
eng
2,025
7
null
2,025
3
3
[BACKGROUND] The importance of health literacy in personal health management is widely recognised in the general population, yet remains poorly understood in some patient groups, including people with spinal cord injury or disorder (SCI/D). [OBJECTIVES] The systematic review had two objectives: (1) to determine the hea...
Digital literacy; Health literacy; Spinal cord disorder; Spinal cord injury; Systematic review; eHealth literacy
1.376
60
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
40,074,049
Analyzing the role of genetic variants in microRNAs and its role as a modulator towards Chronic Obstructive Pulmonary disease (COPD) susceptibility in North Indian population.
Gene
Gene
952
null
10.1016/j.gene.2025.149413
eng
2,025
6
10
2,025
3
10
[BACKGROUND] miRNAs can target numerous genes, with slight expression changes potentially leading to significant alterations in protein-coding gene expression, affecting various biological processes and possibly worsening conditions like COPD. [OBJECTIVES] This study examines the link between six miRNA SNPs (MIR605, MI...
COPD; Chronic Obstructive Pulmonary Disease; MIR25; MicroRNA; Single Nucleotide Polymorphism
0.682
200
Medicine; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,073,826
Real-world experience of cannabidiol in conjunction with clobazam for the treatment of seizures associated with Lennox-Gastaut syndrome and Dravet syndrome: Results from a retrospective multicentre chart review in Germany.
Epilepsy behavior : EB
Epilepsy Behav
166
null
10.1016/j.yebeh.2025.110302
eng
2,025
5
null
2,025
3
11
[BACKGROUND] Lennox-Gastaut syndrome (LGS) and Dravet syndrome (DS) are rare and debilitating forms of epilepsy, characterised by recurrent, severe, drug-resistant seizures and neurodevelopmental impairments. A non-euphoric, plant-derived, highly purified formulation of cannabidiol (CBD; Epidyolex®, 100 mg/mL oral solu...
Antiseizure medication; CBD; Clinical Global Impression of Change; Developmental and epileptic encephalopathies; Epilepsy; Responder rate
null
null
null
null
null
40,073,767
Strategies to enhance nurses' adherence to central line-associated bloodstream infection prevention bundles in the ICU setting: A systematic review.
Heart lung : the journal of critical care
Heart Lung
71
null
10.1016/j.hrtlng.2025.02.009
eng
2,025
null
null
2,025
3
11
[BACKGROUND] The incidence of central line-associated bloodstream infection (CLABSI) in the ICU continues to rise. Despite existing CLABSI bundles to prevent infections, adherence remains suboptimal. [OBJECTIVE] To identify and synthesize the evidence about strategies used to enhance nurses' adherence to CLABSI prevent...
Bundle; Central line-associated bloodstream infections; Compliance; Intensive care unit
null
null
null
null
null
40,073,644
A battle of surgical strategies: Clinically enlarged lateral lymph nodes in patients with locally advanced rectal cancer; extended mesorectal excision (e-TME) versus traditional surgery (TME-alone) a meta-analysis.
Pathology, research and practice
Pathol Res Pract
269
null
10.1016/j.prp.2025.155874
eng
2,025
5
null
2,025
3
7
[BACKGROUND] The infiltration of lateral lymph nodes (LLN) plays a crucial role in the staging and treatment of individuals with locally advanced rectal cancer (LARC). This meta-analysis aimed to compare the efficacy of extended mesorectal excision (eTME) versus traditional mesorectal excision (TME-alone) in patients w...
Extended Mesorectal Excision (eTME); Lateral Lymph Node Dissection (LLND); Long-Term Outcomes; Rectal Cancer; Systemic Chemo-radiotherapy (CRT)
null
72
Cell Biology; Pathology and Forensic Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,073,277
Platelet-rich plasma injections as a second-line treatment in patients with tendinopathy-related chronic pain and failure of conservative treatment: a systematic review and meta-analysis.
Pain medicine (Malden, Mass.)
Pain Med
26
7
10.1093/pm/pnaf022
eng
2,025
7
1
null
null
null
[DESIGN] Platelet-rich plasma (PRP) is a popular treatment option in managing chronic tendinopathies, although the literature is inconsistent, mainly because of significant heterogeneity in patient populations. Patients who failed conservative management may respond differently than those who have not undergone first-l...
PRP; chronic pain; platelet-rich plasma; tendinopathy; treatment
0.982
128
Anesthesiology and Pain Medicine; Medicine; Neurology
Medicine
2,024
40,072,905
Cerebellocerebral connectivity predicts body mass index: a new open-source Python-based framework for connectome-based predictive modeling.
GigaScience
Gigascience
14
null
10.1093/gigascience/giaf010
eng
2,025
1
6
null
null
null
[BACKGROUND] The cerebellum is one of the major central nervous structures consistently altered in obesity. Its role in higher cognitive function, parts of which are affected by obesity, is mediated through projections to and from the cerebral cortex. We therefore investigated the relationship between body mass index (...
BMI; Human Connectome Project (HCP); Python; cerebellum; connectome-based predictive modeling; functional magnetic resonance imaging (fMRI)
null
null
null
null
null
40,072,815
Comparison of intraocular pressure changes in Japanese patients with neovascular age-related macular degeneration treated with aflibercept or faricimab.
Japanese journal of ophthalmology
Jpn J Ophthalmol
69
2
10.1007/s10384-024-01155-2
eng
2,025
3
null
2,025
3
12
[PURPOSE] To assess the short-term changes in intraocular pressure (IOP) following intravitreal injections of aflibercept or faricimab in Japanese patients with neovascular age-related macular degeneration (nAMD). [STUDY DESIGN] Retrospective observational study. [METHODS] This retrospective observational study include...
Aflibercept; Anti-vascular endothelial growth factor; Faricimab; Intraocular pressure; Neovascular age-related macular degeneration
0.834
70
Medicine; Ophthalmology
Medicine
2,024
40,072,716
Atrial and ventricular strain changes after transcatheter pulmonary valve replacement in patients with repaired tetralogy of Fallot: a feature tracking cardiac MRI study.
Japanese journal of radiology
Jpn J Radiol
43
7
10.1007/s11604-025-01765-x
eng
2,025
7
null
2,025
3
12
[PURPOSE] In patients with repaired tetralogy of Fallot, transcatheter or surgical pulmonary valve replacement is recommended. However, it is not clear whether pulmonary valve replacement preserves systolic and diastolic functions of both ventricles. The aim of the study is to investigate the impact of transcatheter pu...
Adolescents; Adults; Children; Congenital heart disease; Feature tracking strain imaging; Heart; Magnetic resonance imaging; Pulmonary valve replacement; Tetralogy of Fallot
0.757
53
Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,072,571
Diagnostic accuracy of IgG 4/IgG and IgG 4 in patients with IgG 4-related disease: a meta-analysis.
Zeitschrift fur Rheumatologie
Z Rheumatol
null
null
10.1007/s00393-025-01637-9
eng
2,025
3
12
2,025
3
12
[OBJECTIVE] This study aimed to evaluate and compare the diagnostic performance of immunoglobulin G4/Immunoglobulin G (IgG 4/IgG) and immunoglobulin G4 (IgG 4) alone in identifying immunoglobulin G4-related disease (IgG 4-RD). [METHODS] A systematic review and meta-analysis were conducted using data from Medline, Embas...
Biomarkers; Diagnostic accuracy; Immunoglobulin G4; Immunoglobulin G4-related disease; Sensitivity and specificity
0.261
43
Rheumatology
Medicine
2,024
40,072,524
Parental Mental Health Conditions and Infant Health Outcomes Among Military Families.
Military medicine
Mil Med
null
null
10.1093/milmed/usaf069
eng
2,025
3
12
2,025
3
12
[INTRODUCTION] Little is known about the effects of parental mental health burdens during pregnancy on infant health among military families, who are subject to various stressors unique to military life. The present study leveraged infant data from the DoD Birth and Infant Health Research (BIHR) program and self-report...
null
0.472
83
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
40,072,438
Association of Diet and Waist-to-Hip Ratio With Brain Connectivity and Memory in Aging.
JAMA network open
JAMA Netw Open
8
3
10.1001/jamanetworkopen.2025.0171
eng
2,025
3
3
2,025
3
3
[IMPORTANCE] Epidemiological studies suggest that lifestyle factors are associated with risk of dementia. However, few studies have examined the association of diet and waist to hip ratio (WHR) with hippocampus connectivity and cognitive health. [OBJECTIVE] To ascertain how longitudinal changes in diet quality and WHR ...
null
3.546
154
Medicine
Medicine
2,024
40,071,739
Extent of surgical repair and outcomes after surgery for type A aortic dissection.
BJS open
BJS Open
9
2
10.1093/bjsopen/zraf003
eng
2,025
3
4
null
null
null
[BACKGROUND] Acute Stanford type A aortic dissection is a severe emergency condition that, if left untreated, is associated with a high mortality rate. The extent of surgical repair may impact the outcomes of these patients. [METHOD] Patients operated for acute type A aortic dissection from a multicentre European regis...
null
1.241
39
Medicine; Surgery
Medicine
2,024
40,071,595
Comparison of antibiotic provision associated with acute sore throat symptom management in community pharmacies in Wales and England: a natural policy experiment.
The Journal of antimicrobial chemotherapy
J Antimicrob Chemother
80
5
10.1093/jac/dkaf057
eng
2,025
5
2
null
null
null
[BACKGROUND] Acute sore throat is managed in community pharmacies in England and Wales under different clinical pathways: Acute Sore Throat Pharmacy First (ASTPF) and Sore Throat Test and Treat (STTT), respectively. ASTPF launched in 2024 and allows antibiotic supply with FeverPAIN scores 4 and 5. STTT launched in 2018...
null
1.209
229
Infectious Diseases; Microbiology; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,071,258
Impact of Enterococcus infection in HSCT recipients: a national analysis.
Le infezioni in medicina
Infez Med
33
1
10.53854/liim-3301-11
eng
2,025
null
null
2,025
3
1
[BACKGROUND] Enterococci are the third most common cause of healthcare-associated infections in the United States, affecting 10-12% of all transplant recipients worldwide. Enterococcal bacteremia complicates the post-transplant recovery and raises mortality to 18%. This study aims to identify factors linked to mortalit...
Enterococcus; Hematopoietic Stem Cell Transplant; Leukemia; infections; mortality
null
null
null
null
null
40,070,874
Case Report: A modified approach to converting ventriculoperitoneal shunt to ventriculoatrial shunt due to recurrent encapsulation of the peritoneal catheter.
Frontiers in surgery
Front Surg
12
null
10.3389/fsurg.2025.1516115
eng
2,025
null
null
2,025
2
25
[BACKGROUND] Hydrocephalus is a condition characterized by the accumulation of cerebrospinal fluid (CSF) in the ventricular system due to various causes, including excessive CSF production, impaired circulation, or absorption dysfunction. This condition is often accompanied by ventricular enlargement, compression of br...
case report; hydrocephalus; rapid exchange technique; ventriculoatrial; ventriculoperitoneal
0.541
48
Surgery
Medicine
2,024
40,070,666
Enhancing the diagnostic efficacy of right-to-left shunt using robot-assisted transcranial Doppler: a quality improvement project.
Frontiers in neurology
Front Neurol
16
null
10.3389/fneur.2025.1512061
eng
2,025
null
null
2,025
2
25
[BACKGROUND] Stroke is the leading cause of adult disability worldwide, with approximately 30% of strokes remaining cryptogenic. One potential important etiology is a patent foramen ovale (PFO), which may contribute to stroke through paradoxical thromboembolism or in situ thromboembolus formation. Recent advancements i...
cryptogenic stroke; patent foramen closure; patent foramen ovale; robotic; transcranial Doppler ultrasound (TCD)
0.993
118
Neurology; Neurology
Medicine; Neuroscience
2,024
40,070,522
Comparative efficacy of advanced and traditional wound dressings in post-operative orthopaedic care for hip and knee surgeries: A randomized controlled trial.
Journal of clinical orthopaedics and trauma
J Clin Orthop Trauma
63
null
10.1016/j.jcot.2025.102933
eng
2,025
4
null
2,025
2
12
[BACKGROUND] This randomized controlled study aimed to evaluate the efficacy of three advanced dressings (Aquacel Ag®, Opsite® Post-Op, and Mepilex Border Post-Op®) versus traditional dressings in post-operative care for patients undergoing orthopaedic hip or knee surgeries. [METHODS] Conducted between August and Decem...
Advanced wound dressings; Orthopaedic surgery; Pain management; Patient comfort; Postoperative care; Surgical site infections
0.672
45
Orthopedics and Sports Medicine
Medicine
2,024
40,070,069
The Role of Glycolipids and their Toxicity in the Context of Nanomaterials and Nanoparticles: A Review of the Literature.
Current drug targets
Curr Drug Targets
26
8
10.2174/0113894501347158250305074908
eng
2,025
null
null
null
null
null
[INTRODUCTION] Diseases triggered by glucose and lipid metabolic disorders, such as hyperglycemia and hyperlipidemia, have become a global health threat. According to statistics, diabetic patients have exceeded 463 million worldwide, and the prevalence of hyperlipidemia is also continuously rising. These glycolipid met...
Glycolipid; glucose metabolism; hyperglycemia.; lipid metabolism; nanomaterial; toxicity
null
null
null
null
null
40,120,922
Transatrial pericardial insufflation of carbon dioxide to facilitate epicardial mapping and ablation of atrial and ventricular arrhythmias.
Heart rhythm
Heart Rhythm
22
7
10.1016/j.hrthm.2025.03.1967
eng
2,025
7
null
2,025
3
20
[BACKGROUND] Epicardial access (EA) is an essential tool for ablation of certain arrhythmias, but conventional techniques carry inherent risks. Carbon dioxide (CO2) insufflation in the pericardium through the coronary sinus aims to facilitate EA but is time-consuming and not widely used. Transatrial pericardial insuffl...
Arrhythmias; Carbon dioxide; Epicardial access; Right atrium; Techniques; Ventricular tachycardia ablation
1.929
165
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,024
40,120,822
Sex differences in pulmonary arterial hypertension: Insights from the FOCUS-PAH registry.
International journal of cardiology
Int J Cardiol
430
null
10.1016/j.ijcard.2025.133180
eng
2,025
7
1
2,025
3
20
[BACKGROUND] Despite the higher incidence of pulmonary arterial hypertension (PAH) in women, sex differences in terms of clinical presentation and prognosis are still uncertain. We assess the impact of sex in patients with PAH. [METHODS] Sex differences were evaluated in the multicenter FOCUS-PAH registry, that include...
FOCUS-PAH; Females; Males; Mortality; Pulmonary arterial hypertension; Sex
1.132
155
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,119,641
Appalachian Numeracy and Literacy and Oral Health, an Ecological Study, PIAAC and BRFSS.
Journal of public health dentistry
J Public Health Dent
85
2
10.1111/jphd.12672
eng
2,025
6
null
2,025
3
22
[OBJECTIVES] Social determinants of health (SDOH) include healthcare access, neighborhood/built environment, social context, economic stability, and education (including literacy and numeracy). These are known factors for health outcomes. The purpose of this research is to consider one SDOH category: general literacy/n...
Appalachian region; health; health education; health literacy; literacy; social determinants of health
0.557
74
Dentistry; Public Health, Environmental and Occupational Health
Dentistry; Medicine
2,024
40,119,609
The Role of Acceptance of Aversive Experiences and Perceived Social Support on the Probability of Relapse Among Patients With Substance Use Disorders.
Journal of psychiatric and mental health nursing
J Psychiatr Ment Health Nurs
32
4
10.1111/jpm.13170
eng
2,025
8
null
2,025
3
22
[BACKGROUND] Substance use disorders are prevalent and pose significant challenges to successful treatment outcomes, with high rates of relapse being a major obstacle. Perceived social support and acceptance of aversive experiences have been identified as potential factors influencing relapse outcomes among patients wi...
acceptance; aversive experience; patients with substance use disorders; perceived social support; probability of relapse
null
null
null
null
null
40,119,545
Association of neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and monocyte-to-high-density lipoprotein ratio with diabetic nephropathy.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
Ther Apher Dial
29
3
10.1111/1744-9987.70008
eng
2,025
6
null
2,025
3
21
[INTRODUCTION] The aim of this study was to determine the relationship between albuminuria and neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and monocyte-to-high density lipoprotein-cholesterol ratio (MHR). [METHODS] Patients with type 2 diabetes mellitus diagnosis, aged over 18, had estimate...
albuminuria; diabetic nephropathy
0.426
62
Hematology; Nephrology
Medicine
2,024
40,119,448
Long-read sequencing identifies copy-specific markers of SMN gene conversion in spinal muscular atrophy.
Genome medicine
Genome Med
17
1
10.1186/s13073-025-01448-2
eng
2,025
3
21
2,025
3
21
[BACKGROUND] The complex 2 Mb survival motor neuron (SMN) locus on chromosome 5q13, including the spinal muscular atrophy (SMA)-causing gene SMN1 and modifier SMN2, remains incompletely resolved due to numerous segmental duplications. Variation in SMN2 copy number, presumably influenced by SMN1 to SMN2 gene conversion,...
Dark genomic regions; Gene conversion; Long-read sequencing; Segmental duplications; Spinal muscular atrophy
5.078
133
Genetics; Genetics; Molecular Biology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,119,397
Identification of novel inflammatory response-related biomarkers in patients with ischemic stroke based on WGCNA and machine learning.
European journal of medical research
Eur J Med Res
30
1
10.1186/s40001-025-02454-1
eng
2,025
3
22
2,025
3
22
[BACKGROUND] Ischemic stroke (IS) is one of the most common causes of disability in adults worldwide. This study aimed to identify key genes related to the inflammatory response to provide insights into the mechanisms and management of IS. [METHODS] Transcriptomic data for IS were downloaded from the Gene Expression Om...
Immune infiltration; Inflammatory response; Ischemic stroke; Nomogram; Personalized treatment
null
70
Medicine
Medicine
2,024
40,119,336
Isolation, expression, and in silico profiling of a thermostable xylanase from Geobacillus stearothermophilus strain NASA267: insights into structural features and agro-waste valorization.
Microbial cell factories
Microb Cell Fact
24
1
10.1186/s12934-025-02672-6
eng
2,025
3
21
2,025
3
21
[BACKGROUND] Xylanase is an industrial enzyme with diverse applications, including nutritional supplements, agro-waste valorization, and paper pulp bleaching. This study aims to investigate the production of recombinant thermostable xylanase for converting plant biomass into fermentable sugars, a key step in various in...
Cloning; GH10 xylanase family; Homology model; TIM barrel fold; Thermal stability; Xylanase
1.103
134
Applied Microbiology and Biotechnology; Bioengineering; Biotechnology
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Immunology and Microbiology
2,024
40,119,321
Mind matters: a comparative study of self-reported severity of depression and cognitive symptoms in China and the USA.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-22356-5
eng
2,025
3
21
2,025
3
21
[BACKGROUND] Individuals' interpretations of health are inherently subjective, influenced by diverse cultural background and upbringing. This study aimed to examine differences in self- reported severity of depression and cognitive symptoms among middle-aged and older adults from China and the United States. [METHODS] ...
Ageing; China; Cognitive; Depression; USA; Vignettes
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,118,794
Carotid Intima-Media Thickness, Carotid Distensibility, and Incident Heart Failure in Older Men: The British Regional Heart Study.
Journal of the American Heart Association
J Am Heart Assoc
14
7
10.1161/JAHA.124.037167
eng
2,025
4
null
2,025
3
21
[BACKGROUND] Carotid intima-media thickness (CIMT) and carotid distensibility are markers of arterial change; however, little is known of the association with incident heart failure (HF). We aimed to assess this. [METHODS] This was a longitudinal analysis of data from the British Regional Heart Study, a prospective coh...
cardiovascular diseases; carotid artery distensibility; heart failure
2.189
152
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,118,660
Translation and Adaptation to Hebrew of the Singers' Voice Handicap Index Questionnaire.
Journal of voice : official journal of the Voice Foundation
J Voice
null
null
10.1016/j.jvoice.2025.02.041
eng
2,025
3
20
2,025
3
20
[OBJECTIVES] This study aimed to present and validate the Hebrew version of the Singing Voice Handicap Index (SVHI-Heb). It also examined possible differences in voice handicap between professional singers and singing students and among singers of various singing styles. [METHODS] The original SVHI questionnaire was tr...
null
0.573
114
LPN and LVN; Otorhinolaryngology; Speech and Hearing
Health Professions; Medicine; Nursing
2,024
40,118,281
Gender differences in the associations between developmental disabilities and anxiety and depression symptoms among U.S. children: Insights from the 2021 National Health Interview Survey.
Journal of affective disorders
J Affect Disord
380
null
10.1016/j.jad.2025.03.092
eng
2,025
7
1
2,025
3
19
[BACKGROUND] Limited research has explored the associations between developmental disabilities and symptoms of anxiety and depression among U.S. children during the COVID-19 pandemic. [OBJECTIVE] This study investigates the associations between developmental disabilities and symptoms of anxiety and depression among U.S...
ADHD; Anxiety; Autism spectrum disorder; COVID-19; Children; Depression; Developmental disabilities; Gender difference
2.121
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
40,118,150
The impact of the immunological context on outcomes of solid cancer patients treated with genotype-matched targeted therapies: a comprehensive review.
Annals of oncology : official journal of the European Society for Medical Oncology
Ann Oncol
36
7
10.1016/j.annonc.2025.03.007
eng
2,025
7
null
2,025
3
19
[BACKGROUND] Outcomes with genotype-matched targeted therapy in solid cancer patients are heterogeneous: some have exceptional responses, whereas others have primary progression. This review explores the immunobiological features which may underlie this differential response. [METHODS] We conducted a literature review ...
immunological context; precision medicine; targeted therapy
19.072
311
Hematology; Medicine; Oncology
Medicine
2,024
40,118,117
Effect of albumin treatment duration on response rates and outcomes in patients with cirrhosis and acute kidney injury.
Journal of hepatology
J Hepatol
83
3
10.1016/j.jhep.2025.03.008
eng
2,025
9
null
2,025
3
19
[BACKGROUND AND AIMS] Guidelines recommended volume expansion with albumin for 48 hours for patients with cirrhosis and acute kidney injury (AKI) to correct hypovolemia and rule out prerenal AKI. A recent update in the ADQI-ICA consensus guidelines suggested shortening this duration to 24 hours, primarily based on expe...
ICA; KDIGO; acute kidney injury; albumin; ascites; cirrhosis; hepatorenal syndrome; portal hypertension; terlipressin; volume therapy
10.575
319
Hepatology
Medicine
2,024
40,117,909
Virtual reality improves pain threshold and recall in healthy adults: A randomized, crossover study.
Journal of clinical anesthesia
J Clin Anesth
103
null
10.1016/j.jclinane.2025.111816
eng
2,025
4
null
2,025
3
21
[STUDY OBJECTIVE] Virtual reality (VR) is an emerging technology increasingly used to ameliorate acute and chronic pain although controlled, quantifiable data are limited. The purpose of this study is to evaluate VR's effect on heat pain threshold (HPT), pressure pain threshold (PPT), immediate pain and anxiety, and re...
Anesthesia; Anxiety; Pain; Pain threshold; Virtual reality
1.333
86
Anesthesiology and Pain Medicine
Medicine
2,024
40,117,697
Lipoprotein (a) Distribution in Aortic Stenosis Patients: Are Lp(a) Reducing Agents the Ultimate Solution?
JACC. Advances
JACC Adv
4
4
10.1016/j.jacadv.2025.101662
eng
2,025
4
null
2,025
3
21
[BACKGROUND] There is currently no medical therapy that can slow down/stop the progression of aortic stenosis (AS). Novel drugs lowering lipoprotein(a) (Lp[a]), a proinflammatory particle linked to AS development, are currently under evaluation, but the proportion of patients with AS and elevated Lp(a) who might benefi...
aortic stenosis; lipoprotein (a)
null
null
null
null
null
40,117,417
Clinical Outcomes and Electrophysiological Characteristics of Partial Perforation After Left Bundle Branch Area Pacing.
JACC. Clinical electrophysiology
JACC Clin Electrophysiol
11
6
10.1016/j.jacep.2025.01.016
eng
2,025
6
null
2,025
3
19
[BACKGROUND] Septal perforation, defined as partial or complete protrusion of a lead helix, is a potential complication of left bundle branch area pacing, theoretically increasing risks of pacing failure and thromboembolism. However, no studies have examined the long-term prognosis of patients with partial perforations...
conduction system pacing; helix-only perforation; left bundle branch pacing; left ventricular septal pacing; microperforation; septal perforation
null
null
null
null
null
40,117,255
Vascular endothelial growth factor D potential predictor and screening marker in ovarian carcinoma.
Ceska gynekologie
Ceska Gynekol
90
1
10.48095/cccg202522
eng
2,025
null
null
null
null
null
[INTRODUCTION] Until now, it is still true that late detection of ovarian cancer is a major cause of its poor prognosis. So far, no sufficiently sensitive and specific marker or combination of markers and imaging methods has been identified that would unambiguously allow the detection of early potentially highly-curabl...
VEGF-D; gynaecologic oncology; lymphangiogenesis; ovarian cancer; ovarian carcinoma
null
null
null
null
null
40,117,180
Genomic and transcriptomic analyses of Heteropoda venatoria reveal the expansion of P450 family for starvation resistance in spiders.
GigaScience
Gigascience
14
null
10.1093/gigascience/giaf019
eng
2,025
1
6
null
null
null
[BACKGROUND] Research on the mechanism of starvation resistance can help reveal how animals adjust their physiology and behavior to adapt to the uncertainty of food resources. A low metabolic rate is a significant characteristic of spider physiological activity and can increase spider starvation resistance and adapt to...
Heteropoda venatoria; cytochrome P450; gene family expansion; starvation resistance; transcriptomics
null
null
null
null
null
40,117,070
Serum matrix metalloproteinase-9 as a potential biomarker for obstructive sleep apnea severity.
Sleep & breathing = Schlaf & Atmung
Sleep Breath
29
2
10.1007/s11325-025-03287-2
eng
2,025
3
21
2,025
3
21
[PURPOSE] We aimed to investigate the associations between serum matrix metalloproteinase (MMP)-2 and MMP-9 levels and obstructive sleep apnea (OSA) severity with a focus on nocturnal hypoxemia. [METHODS] The OSA patients (n = 105) were recruited from a prospective sleep apnea cohort after polysomnography, with 27 heal...
Biomarker; Hypoxemia; Matrix metalloproteinase; Obstructive sleep apnea; Severity
null
null
null
null
null
40,116,752
Efficiency Improvement of the Clinical Pathway in Cardiac Monitor Insertion and Follow-Up: Retrospective Analysis.
JMIR cardio
JMIR Cardio
9
null
10.2196/67774
eng
2,025
3
21
2,025
3
21
[BACKGROUND] The insertable cardiac monitor (ICM) clinical pathway in Tampere Heart Hospital, Finland, did not correspond to the diagnostic needs of the population. There has been growing evidence of delegating the insertion from cardiologists to specially trained nurses and outsourcing the remote follow-up. However, i...
clinical pathway; efficiency improvement; insertable cardiac monitor; nurse-led service; remote monitoring; task shifting
null
null
null
null
null
40,116,712
A Comparison of Neighborhood Socioeconomic Deprivation Measures and the Association with Survival among Black and White Women with Endometrial Cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Cancer Epidemiol Biomarkers Prev
34
6
10.1158/1055-9965.EPI-24-1833
eng
2,025
6
3
null
null
null
[BACKGROUND] Black women with endometrial cancer have twice the mortality compared with White. Survival disparities remain after accounting for individual-level socioeconomic and cancer-related factors. We investigated associations between area-based deprivation and survival and explored whether area-based deprivation ...
null
null
null
null
null
null
40,116,326
Identifying potential drug targets for sepsis-related adult respiratory distress syndrome through comprehensive genetic analysis and druggability assessment.
Journal of global health
J Glob Health
15
null
10.7189/jogh.15.04117
eng
2,025
3
21
2,025
3
21
[BACKGROUND] Sepsis-related adult respiratory distress syndrome (ARDS) is a life-threatening condition characterised by a high mortality rate. This underscores the pressing requirement to identify and develop potential therapeutic targets for the severe condition. This study investigated the genetic predisposition to s...
null
1.172
71
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,024
40,116,105
The Correlation between GSK3β and miR-140 and its Effect on the Pathogenesis of Asthma.
Discovery medicine..
Discov Med
37
194
10.24976/Discov.Med.202537194.49
eng
2,025
3
null
null
null
null
[BACKGROUND] MicroRNAs (miRNAs) are linked to asthma progression. In this study, we aimed to decipher the functional role of miR-140 and delineate its link to the mechanism behind the progression of asthma. [METHODS] BALB/c mice were divided into four groups, designated as control, asthma, Agomir negative control (NC),...
airway inflammation; asthma; miR-140
null
null
null
null
null
40,116,052
Pediatric Dog Bite Injury Trends During the COVID-19 Pandemic.
Pediatric emergency care
Pediatr Emerg Care
41
7
10.1097/PEC.0000000000003378
eng
2,025
7
1
2,025
3
21
[OBJECTIVE] To examine differences between dog bite injuries among below 18-year-old patients seen in pediatric emergency departments (PEDs) during the COVID-19 pandemic to those seen before the pandemic. [METHODS] This is a subanalysis of a cross-sectional study of injured children below 18 years old seen in 40 PEDs, ...
COVID-19; Dog bites; pediatric injuries
0.549
79
Emergency Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,024
40,115,993
Neurological long COVID in the outpatient clinic: Is it so long?
European journal of neurology
Eur J Neurol
32
3
10.1111/ene.16510
eng
2,025
3
null
null
null
null
[BACKGROUND AND PURPOSE] Neurological involvement in long COVID (coronavirus disease 2019) is well known. In a previous study we identified two subtypes of neurological long COVID, one characterized by memory disturbances, psychological impairment, headache, anosmia and ageusia, and the other characterized by periphera...
clustering; neurological long COVID; recovery rate; vaccination
1.561
151
Neurology; Neurology
Medicine; Neuroscience
2,024
40,115,779
Evaluation of the clinical and sociodemographic features of patients with vitiligo from the central region of Romania.
Frontiers in medicine
Front Med (Lausanne)
12
null
10.3389/fmed.2025.1544184
eng
2,025
null
null
2,025
3
6
[BACKGROUND] In this study, we aimed to investigate and analyze the clinical and sociodemographic features and possible correlation with factors associated with the development of vitiligo in a cohort of patients suffering from this disease in the central region of Romania. [METHODS] Patients diagnosed with vitiligo fr...
autoimmune disease; clinical features; cohort; pigmentation disorder; sociodemographic features; vitiligo
0.962
102
Medicine
Medicine
2,024
40,115,746
A Hidden Mark of a Troubled Past: Neuroimaging and Transcriptomic Analyses Reveal Interactive Effects of Maternal Immune Activation and Adolescent THC Exposure Suggestive of Increased Neuropsychiatric Risk.
Biological psychiatry global open science
Biol Psychiatry Glob Open Sci
5
3
10.1016/j.bpsgos.2025.100452
eng
2,025
5
null
2,025
1
23
[BACKGROUND] Maternal exposure to infections during gestation has been shown to predispose individuals to neuropsychiatric disorders. Additionally, clinical data suggest that cannabis use may trigger the onset of schizophrenia in vulnerable individuals. However, the direction of causality remains unclear. [METHODS] To ...
Adolescence; Cannabinoids; Maternal immune activation; Orbitofrontal cortex; PET; Transcriptome
null
null
null
null
null
40,115,577
Understanding women's knowledge and attitudes toward the use of emergency contraceptive methods at King Abdulaziz Medical City, Jeddah, Saudi Arabia.
Journal of family medicine and primary care
J Family Med Prim Care
14
2
10.4103/jfmpc.jfmpc_1567_24
eng
2,025
2
null
2,025
2
21
[BACKGROUND] Emergency contraception (EC) is an effective and safe choice for preventing unintended pregnancies if taken within the first 4 to 5 days. The review of existing literature indicates that EC options are often underused globally, primarily due to insufficient awareness among women. [AIM] To determine the kno...
Emergency contraception; knowledge; primary health care; unintended pregnancy
null
null
null
null
null
40,115,551
Inflammatory biomarkers and adverse outcome in COVID-19: Prelude for future viral pandemics.
Journal of family medicine and primary care
J Family Med Prim Care
14
2
10.4103/jfmpc.jfmpc_1326_24
eng
2,025
2
null
2,025
2
21
[BACKGROUND] Dysregulated inflammatory response plays a key role in the pathogenesis of COVID-19. The role of inflammatory markers to predict adverse clinical outcome is still controversial. The aim of this study was to analyze the association of inflammatory markers with disease outcomes independent of the effect of a...
COVID-19; CRP; D-Dimer; IL6; LDH; inflammation; serum ferritin
null
null
null
null
null
40,115,187
Antibacterial activity and mechanism of Sodium houttuyfonate against heteroresistant Pseudomonas aeruginosa.
Frontiers in microbiology
Front Microbiol
16
null
10.3389/fmicb.2025.1523182
eng
2,025
null
null
2,025
3
6
[BACKGROUND] Pseudomonas aeruginosa is a common gram-negative opportunistic pathogen that is now commonly treated with carbapenems, such as Meropenem. However, the increasing rate of emergence of heteroresistant strains poses a therapeutic challenge. Therefore, we examined the antibacterial activity of Sodium houttuyfo...
Meropenem; Pseudomonas aeruginosa; Sodium houttuyfonate; biofilm; heteroresistant Pseudomonas aeruginosa
1.172
259
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,024
40,115,111
Machine Learning Predicts 30-Day Readmission and Mortality After Surgical Resection of Head and Neck Cancer.
OTO open
OTO Open
9
1
10.1002/oto2.70100
eng
2,025
null
null
2,025
3
20
[OBJECTIVE] To develop and validate a machine learning model to identify patients at high risk of 30-day mortality and hospital readmission using routinely collected health care data. [STUDY DESIGN] Prognostic predictive modeling and retrospective cohort study. The study was conducted in 2024 using data from 2006 to 20...
National Cancer Database; head and neck squamous cell carcinoma; machine learning; mortality; readmission; surgical resection
0.69
20
Otorhinolaryngology; Surgery
Medicine
2,024
40,115,089
Treatment and prognosis of patients with Kawasaki disease and giant coronary artery aneurysm: a retrospective observational study.
Cardiovascular diagnosis and therapy
Cardiovasc Diagn Ther
15
1
10.21037/cdt-24-289
eng
2,025
2
28
2,025
2
25
[BACKGROUND] There is no established regimen for antithrombotic therapy in patients with Kawasaki disease (KD) who develop giant coronary artery aneurysm (GA). This single-center retrospective study evaluated the outcome of a unified antithrombotic regimen in these patients. [METHODS] Sixteen KD patients with GA onset ...
Kawasaki disease; coronary artery disease; major adverse cardiovascular events; myocardial infarction
0.707
47
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,115,024
Application of a multifunctional chemotherapy infusion device for reducing antineoplastic drug extravasation.
Frontiers in oncology
Front Oncol
15
null
10.3389/fonc.2025.1539389
eng
2,025
null
null
2,025
3
6
[OBJECTIVE] This study aimed to address the challenges associated with antineoplastic drug extravasation during intravenous administration, through the development of a novel chemotherapy infusion device. A secondary objective was to mitigate associated risks to healthcare personnel, patients, caregivers and the enviro...
antineoplastic drugs; drug extravasation; infusion device; injury; intravenous infusion; multifunctional chemotherapy
1.075
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,114,823
Correlation of renal function with intra-patient variability of tacrolimus concentration among recipients of renal transplants: a 10-year study.
Translational andrology and urology
Transl Androl Urol
14
2
10.21037/tau-24-564
eng
2,025
2
28
2,025
2
25
[BACKGROUND] Tacrolimus is one of the most commonly used basic immunosuppressants nowadays, but the high variability of tacrolimus blood concentration often leads to kidney transplant recipients frequently experiencing drug concentrations above or below the target concentration, resulting in renal toxicity or rejection...
Intra-patient variability (IPV); kidney transplantation; renal function; retrospective study; tacrolimus
0.671
57
Reproductive Medicine; Urology
Medicine
2,024
40,114,769
The effect of house dust mite sensitization on skin dermis thickness in children with allergic respiratory diseases.
Postepy dermatologii i alergologii
Postepy Dermatol Alergol
42
1
10.5114/ada.2025.147855
eng
2,025
2
null
2,025
2
20
[INTRODUCTION] An impaired skin barrier has been reported in allergic diseases. [AIM] In this study, we aimed to evaluate dermis thickness in children with house dust allergy without skin symptoms. [MATERIAL AND METHODS] This cross-sectional study included children aged 4-18 years with asthma and/or allergic rhinitis. ...
allergy; children; house dust mite sensitization; skin barrier; skin thickness
0.516
40
Dermatology; Immunology and Allergy
Medicine
2,024
40,114,602
Use of a community care coordination team to reduce emergency department utilization and hospital readmissions for the highest utilizers.
Journal of osteopathic medicine
J Osteopath Med
null
null
10.1515/jom-2024-0255
eng
2,025
3
24
2,025
3
24
[CONTEXT] A small percentage of patients comprise a high proportion of healthcare utilization, particularly the costs associated with Emergency Department (ED) visits and inpatient hospitalization readmissions. [OBJECTIVES] The purpose of this study was to demonstrate a decrease in ED utilization and hospital readmissi...
community health workers; healthcare disparities; healthcare spending; healthcare utilization
0.445
61
Complementary and Alternative Medicine; Complementary and Manual Therapy
Health Professions; Medicine
2,024
40,114,263
Intraoperative fentanyl in endoscopic procedures and their impact on PACU time and costs.
Perioperative medicine (London, England)
Perioper Med (Lond)
14
1
10.1186/s13741-025-00515-x
eng
2,025
3
20
2,025
3
20
[BACKGROUND] Extended stays in the postanesthesia care unit (PACU) pose challenges in high-volume endoscopies. This study investigates the impact of intraoperative fentanyl use on PACU duration, postoperative pain, and financial implications in outpatient endoscopy. [METHOD] A retrospective analysis of upper/lower endo...
Anesthesiology; Endoscopy; Fentanyl; Pain; Postanesthesia care unit (PACU)
null
null
null
null
null
40,114,248
Kearns-Sayre syndrome presenting with progressive external ophthalmoplegia and third-degree atrioventricular block diagnostic challenge in resource-limited settings: a case report.
Journal of medical case reports
J Med Case Rep
19
1
10.1186/s13256-025-05086-5
eng
2,025
3
20
2,025
3
20
[BACKGROUND] Kearns-Sayre syndrome is a rare autosomal recessive mitochondrial disorder characterized by progressive external ophthalmoplegia and pigmentary retinopathy. Onset typically occurs before the age of 20 years and is attributed to mutations within mitochondrial DNA affecting proteins critical for the oxidativ...
Complete heart block; Mitochondrial disorder; Pigmentary retinopathy; Progressive external ophthalmoplegia
0.31
43
Medicine
Medicine
2,024
40,114,151
Relocation of hospital facilities: guidelines for resilient performance.
BMC health services research
BMC Health Serv Res
25
1
10.1186/s12913-025-12339-y
eng
2,025
3
20
2,025
3
20
[BACKGROUND] The relocation of a hospital unit is a complex process that demands both formal planning and informal self-organization on the spot to cope with unexpected events under time pressure. However, guidelines to support this process are fragmented and concealed in the literature. This article addresses this gap...
Complexity; Hospital relocation; Organizational resilience; Surgical unit
1.174
157
Health Policy
Medicine
2,024
40,114,125
Influence of alloplastic materials, biologics, and their combinations, along with defect characteristics, on short-term intrabony defect surgical treatment outcomes: a systematic review and network meta-analysis.
BMC oral health
BMC Oral Health
25
1
10.1186/s12903-025-05782-0
eng
2,025
3
20
2,025
3
20
[BACKGROUND] Treating periodontal intrabony defects remains challenging, alloplast materials and biologics are increasingly utilized to improve regeneration outcomes. However, comparative efficacy on alloplast materials remains limited. This study aimed to evaluate the effectiveness of alloplastic materials, both alone...
Bioglass; Biologics; Biphasic calcium phosphate; Defect depth; Defect morphology; Intrabony defects; Nanocrystalline hydroxyapatite
0.843
80
Dentistry
Dentistry
2,024
40,114,086
Genome-wide identification of the P4ATPase gene family and its response to biotic and abiotic stress in soybean (Glycine max L.).
BMC genomics
BMC Genomics
26
1
10.1186/s12864-025-11468-2
eng
2,025
3
20
2,025
3
20
[BACKGROUND] Soybean is an important legume crop and has significant agricultural and economic value. P4-ATPases (aminophospholipid ATPases, ALAs), one of the classes of P-type ATPases, can transport or flip phospholipids across membranes, creating and maintaining lipid asymmetry and playing crucial roles in plant grow...
Bioinformatics analysis; Expression patterns; P4-ATPases; Stress response
1.003
208
Biotechnology; Genetics
Biochemistry, Genetics and Molecular Biology
2,024
40,113,249
Evaluation of compliance with smoke-free regulations in a multi-ethnic city in Western China: a mixed-methods study.
Tobacco control
Tob Control
null
null
10.1136/tc-2024-059077
eng
2,025
3
20
2,025
3
20
[BACKGROUND] China has enacted subnational smoke-free legislations, which requires compliance evaluations to provide data for future implementation planning. This study comprehensively assessed smoke-free regulation compliance in Xining in Western China. [METHODS] Conducted in November and December 2023, the study used...
Public policy; Secondhand smoke; Surveillance and monitoring
2.305
147
Health; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,024
40,113,131
Psychosocial Risk Assessment for Heart Transplantation: Evaluating for Bias and Impact on Post-transplant Outcomes.
Journal of cardiac failure
J Card Fail
null
null
10.1016/j.cardfail.2025.02.016
eng
2,025
3
18
2,025
3
18
[BACKGROUND] Pretransplant psychosocial risk (PSR) assessment is subjective, so we investigated potential biases and the relationship between assessed PSR and post-transplant outcomes at our heart transplant center. [METHODS] Between 05/2004 and 01/2021, 479 heart transplant (HT) recipients had a pre-transplant psychos...
Heart transplantation; affluence; bias; psychosocial evaluation; psychosocial risk; socioeconomic status
2.16
127
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,113,100
The Efficacy of Texture and Color Enhancement Imaging Observation in the Detection of Colorectal Lesions: A Multicenter, Randomized Controlled Trial (deTXIon Study).
Gastroenterology
Gastroenterology
169
2
10.1053/j.gastro.2025.03.007
eng
2,025
8
null
2,025
3
18
[BACKGROUND AND AIMS] Colonoscopy is the gold standard for detecting and resecting adenomas and early-stage cancers to reduce colorectal cancer (CRC) incidence and mortality rates. This study aimed to confirm the superiority of texture and color enhancement imaging (TXI) over white light imaging (WLI) in detecting colo...
Colonoscopy; Colorectal Cancer; Colorectal Polyp; Detection; Image Enhancement
7.195
482
Gastroenterology; Hepatology
Medicine
2,024
40,112,277
Assessment of utilization of automated systems and laboratory information management systems in clinical microbiology laboratories in Thailand.
PloS one
PLoS One
20
3
10.1371/journal.pone.0320074
eng
2,025
null
null
2,025
3
20
[INTRODUCTION] Clinical microbiology laboratories are essential for diagnosing and monitoring antimicrobial resistance (AMR). Here, we assessed the systems involved in generating, managing and analyzing blood culture data in these laboratories in an upper-middle-income country. [METHODS] From October 2023 to February 2...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
40,111,564
Elevated VRK1 levels after androgen deprivation therapy promote prostate cancer progression by upregulating YAP1 expression.
Journal of cancer research and clinical oncology
J Cancer Res Clin Oncol
151
3
10.1007/s00432-025-06168-z
eng
2,025
3
20
2,025
3
20
[PURPOSE] Vaccinia-related kinase 1 (VRK1) is a serine-threonine kinase involved in the proliferation and migration of various cancer cells. However, its role in prostate cancer (PCa), particularly in the development of therapeutic resistance, remains unclear. [METHODS] We established an androgen-independent PCa cell l...
AR; Castration-resistant; Prostate cancer; VRK1; YAP1
0.91
114
Medicine; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,111,480
Healthcare and productivity cost of osteoporosis: a Danish register-based quasi-experimental study.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Osteoporos Int
36
5
10.1007/s00198-025-07453-w
eng
2,025
5
null
2,025
3
20
[UNLABELLED] Osteoporosis significantly impacts healthcare costs in Denmark, with annual expenses exceeding €3097 per individual. The total annual burden of healthcare and productivity losses attributed to osteoporosis in Denmark surpasses €2 billion. Effective prevention, early detection, and management strategies sho...
Danish registers; Healthcare and productivity cost; Osteoporosis; Register based study
1.466
201
Endocrinology, Diabetes and Metabolism; Medicine
Medicine
2,024
40,111,368
Practice Patterns and Survival Outcomes of Immunotherapy for Metastatic Colorectal Cancer.
JAMA network open
JAMA Netw Open
8
3
10.1001/jamanetworkopen.2025.1186
eng
2,025
3
3
2,025
3
3
[IMPORTANCE] Immune checkpoint inhibitors (ICIs) have been approved for treatment of microsatellite instable (MSI-H) metastatic colorectal cancer (mCRC), but factors associated with receipt and efficacy of ICIs in routine clinical practice remain largely unknown. [OBJECTIVE] To identify factors associated with receipt ...
null
3.546
154
Medicine
Medicine
2,024
40,110,267
Retrospective comparative cohort analysis of Darn and Lichtenstein repair methods for bilateral inguinal hernias in adult males in a low-resource setting: a single-centre study in Sudan.
Annals of medicine and surgery (2012)
Ann Med Surg (Lond)
87
2
10.1097/MS9.0000000000002859
eng
2,025
2
null
2,025
1
31
[BACKGROUND] Inguinal hernias are a common surgical condition that, if untreated, can lead to severe complications. Bilateral inguinal hernias add challenges due to increased recurrence and postoperative risks. Although Lichtenstein repair, a mesh-based approach, is the gold standard for its low recurrence, Darn repair...
Darn repair; Lichtenstein repair; bilateral inguinal hernia; comparative analysis; non-mesh hernia repair; resource-limited settings; surgical outcomes
null
null
null
null
null
40,110,214
An ensemble learning model for detection of pulmonary hypertension using electrocardiogram, chest X-ray, and brain natriuretic peptide.
European heart journal. Digital health
Eur Heart J Digit Health
6
2
10.1093/ehjdh/ztae097
eng
2,025
3
null
2,025
1
16
[AIMS] Delayed diagnosis of pulmonary hypertension (PH) is a known cause of poor patient prognosis. We aimed to develop an artificial intelligence (AI) model, using ensemble learning method to detect PH using electrocardiography (ECG), chest X-ray (CXR), and brain natriuretic peptide (BNP), facilitating accurate detect...
Diagnosis improvement; Ensemble learning; Multimodality artificial intelligence; Pulmonary hypertension
1.494
21
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,110,007
Effect of lattice CO2 laser combined with Kegel exercise mild moderate stress urinary incontinence and postpartum depression anxiety.
World journal of psychiatry
World J Psychiatry
15
3
10.5498/wjp.v15.i3.103252
eng
2,025
3
19
2,025
3
19
[BACKGROUND] Postpartum stress urinary incontinence (SUI) symptoms affect a patient's daily activities and quality of life and increase the negative emotions that they experience. At present, there is no research on the effect of fractional CO2 laser treatment combined with Kegel exercise on postpartum SUI and postpart...
Anxiety; Depression; Kegel exercise; Lattice CO2 laser; Postpartum stress urinary incontinence
null
null
null
null
null
40,109,911
Protracted cluster of Group A Streptococcal infection among individuals receiving wound care in the community, North East England, 2022: an outbreak report.
Antimicrobial stewardship & healthcare epidemiology : ASHE
Antimicrob Steward Healthc Epidemiol
5
1
10.1017/ash.2025.44
eng
2,025
null
null
2,025
3
17
[BACKGROUND] Outbreaks of Group A Streptococcal (GAS) infection are difficult to detect in community healthcare settings and present unique challenges for infection prevention and control (IPC). We describe investigation of a cluster of GAS among individuals receiving wound care from the same community integrated care ...
null
null
null
null
null
null
40,109,812
Ethambutol-Induced Optic Neuropathy: A Retrospective Study of Incidences and Risk Factors.
Cureus
Cureus
17
2
10.7759/cureus.79160
eng
2,025
2
null
2,025
2
17
[PURPOSE] The present study aims to determine the incidences of ethambutol-induced optic neuropathy (EON) and its associated risk factors in Central Indian tertiary care centers. [MATERIALS AND METHODS] A single-centered retrospective observational study was conducted. Data was collected from the Directly Observed Ther...
ethambutol; ethambutol-induced optic neuropathy (eon); rnfl thickness; tuberculosis
null
null
null
null
null
40,109,623
Advances in diabetic cardiomyopathy: current and potential management strategies and emerging biomarkers.
Annals of medicine and surgery (2012)
Ann Med Surg (Lond)
87
1
10.1097/MS9.0000000000002857
eng
2,025
1
null
2,025
1
9
[BACKGROUND] Diabetic cardiomyopathy (DCM) is a significant complication of diabetes mellitus (DM) and a major contributor to heart failure (HF). Despite its prevalence and impact, there is a notable lack of targeted therapies, highlighting the need for ongoing research into novel treatment strategies. Current manageme...
biomarkers; diabetic cardiomyopathy; diagnosis; management; treatment strategies
null
null
null
null
null
40,108,738
The impact of central sensitization on perioperative pain in TKA: a retrospective cohort study.
Knee surgery related research
Knee Surg Relat Res
37
1
10.1186/s43019-025-00263-8
eng
2,025
3
19
2,025
3
19
[BACKGROUND] Total knee arthroplasty (TKA) is an established surgical procedure for severe knee osteoarthritis (KOA) that has provided excellent outcomes. While several studies have reported that patients with preoperative central sensitization (CS) experienced worse pre- and post-operative pain and outcomes, the evide...
Central sensitization; KOOS pain; Knee osteoarthritis; Self-efficacy; Total knee arthroplasty
null
null
null
null
null
40,108,608
Radiological disaster response self-efficacy of final-year nursing students and interns at Jazan University, Saudi Arabia.
BMC medical education
BMC Med Educ
25
1
10.1186/s12909-025-06976-4
eng
2,025
3
19
2,025
3
19
[BACKGROUND] Nuclear and radiological accidents pose serious public health risks, requiring healthcare professionals to be prepared with specific response skills. Given the essential role of nurses in disaster situations, this study evaluates the self-efficacy of final-year nursing students and interns at Jazan Univers...
Disaster response; Nuclear emergency; Nursing education; Radiological disaster; Self-efficacy
0.947
107
Education; Medicine
Medicine; Social Sciences
2,024
40,108,570
Assessment of the effects of vitreopapillary adhesion on optic disc and macular parameters, and peripapillary choroidal vasculature.
BMC ophthalmology
BMC Ophthalmol
25
1
10.1186/s12886-025-03975-3
eng
2,025
3
19
2,025
3
19
[BACKGROUND] To investigate the effects of vitreopapillary adhesion (VPA) on optic disc and macular parameters and on the peripapillary choroidal vasculature. [METHODS] This retrospective study included 47 eyes of 47 participants with VPA, all of whom had no history of systemic or ocular disease. Optical coherence tomo...
Optic disc; Posterior vitreous detachment; Vitreopapillary adhesion; Vitreopapillary traction
0.72
67
Medicine; Ophthalmology
Medicine
2,024
40,108,532
Interpersonal violence-related physical injury in low- and middle-income countries and its association with markers of socioeconomic status: a systematic review.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-21321-6
eng
2,025
3
19
2,025
3
19
[BACKGROUND] Interpersonal violence-related physical injury (IPVRPI) is a leading cause of death in low- and middle-income countries (LMICs), yet reliable data relating socioeconomic status (SES) and IPVRPI in these settings are lacking. We analyzed existing literature on associations between SES and IPVRPI in LMICs to...
Education level; Injury; Interpersonal violence; Low- and Middle-Income Countries (LMICs); Physical trauma; Socioeconomic status; Unemployment
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,108,514
Pubertal developmental, body mass index, and cardiovascular autonomic function in children and adolescents with and without autism spectrum disorder: a four-time point accelerated longitudinal study.
Journal of neurodevelopmental disorders
J Neurodev Disord
17
1
10.1186/s11689-025-09602-y
eng
2,025
3
19
2,025
3
19
[BACKGROUND] The Autonomic Nervous System (ANS) regulates 'automatic' functions such as heart rate, and alterations may have significant impacts on health outcomes. Cardiovascular measures of autonomic function such as heart rate variability are of interest as biological markers in autism spectrum disorder (ASD). The i...
Autism; Autonomic; Cardiovascular; Health; Heart rate; Physical; Pubertal development; Variability
1.296
64
Cognitive Neuroscience; Neurology; Pathology and Forensic Medicine; Pediatrics, Perinatology and Child Health
Medicine; Neuroscience
2,024
40,108,499
The prevalence of nonalcoholic fatty liver disease in people living with HIV: a systematic review and meta-analysis.
BMC infectious diseases
BMC Infect Dis
25
1
10.1186/s12879-025-10455-y
eng
2,025
2
19
2,025
2
19
[BACKGROUND] Owing to long-term antiretroviral therapy (ART), the incidence of non-HIV-related chronic diseases is increasing, and liver disease is the leading cause of increased AIDS mortality. Moreover, the prevalence of NAFLD and liver fibrosis has been reported to vary widely across regions and studies. There is no...
HIV; Liver fibrosis; Meta-analysis; NAFLD
1.035
137
Infectious Diseases
Medicine
2,024
40,108,078
Rationale and Design of ANTHOLOGY: An ATTR Amyloidosis Real-World Evidence Program Aiming to Address Gaps in Amyloidosis Care.
Cardiology and therapy
Cardiol Ther
null
null
10.1007/s40119-025-00402-y
eng
2,025
3
19
2,025
3
19
[INTRODUCTION] Patients with amyloid transthyretin (ATTR) amyloidosis typically experience rapid disease progression, poor treatment outcomes, irreversible loss of health-related quality of life (HRQoL), and premature mortality. Early diagnosis is vital. However, diagnostic delays and misdiagnosis are common due to und...
ATTR amyloidosis; HRQoL; Methodology; Observational; Real-world evidence
0.892
26
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,107,928
Parental knowledge and beliefs about sleep health for children with overweight and obesity.
Sleep health
Sleep Health
11
3
10.1016/j.sleh.2025.01.011
eng
2,025
6
null
2,025
3
18
[OBJECTIVE] To examine parental knowledge and beliefs about sleep health and their relation to sleep practices in a community sample of school-age children with overweight and obesity. [METHODS] Sleep in 246 overweight or obese children was assessed objectively using actigraphy. Parents completed a questionnaire about ...
Actigraphy; Children; Obesity; Overweight; Parent knowledge and beliefs; Sleep
1.285
51
Behavioral Neuroscience; Health; Neuropsychology and Physiological Psychology; Social Sciences
Neuroscience; Psychology; Social Sciences
2,024
40,107,509
Efficacy and safety of high-vs low-dose sirolimus in patients with kaposiform hemangioendothelioma: A randomized clinical trial.
Journal of the American Academy of Dermatology
J Am Acad Dermatol
93
1
10.1016/j.jaad.2025.03.023
eng
2,025
7
null
2,025
3
17
[BACKGROUND] It remains unknown whether low-dose sirolimus can replace high-dose sirolimus for the treatment of kaposiform hemangioendothelioma (KHE) without the Kasabach-Merritt phenomenon. [OBJECTIVE] To evaluate the noninferiority and safety of low-dose versus high-dose sirolimus in KHE patients. [METHODS] This rand...
efficacy; kaposiform hemangioendothelioma; safety; sirolimus
1.315
256
Dermatology
Medicine
2,024
40,107,455
Repeatability of Pig True Ileal Amino Acid Digestibility Coefficients: Among and Within Laboratories.
The Journal of nutrition
J Nutr
155
5
10.1016/j.tjnut.2025.03.013
eng
2,025
5
null
2,025
3
17
[BACKGROUND] When determining true ileal amino acid (AA) digestibility values in the growing pig to calculate digestible indispensable AA score, there are aspects of the protocol, both genetic and environmental, that vary between laboratories. [OBJECTIVES] This study aimed to determine true ileal AA digestibility in 9 ...
AAs; DIAAS; pig; protein quality; true ileal AA digestibility
1.152
306
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024