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40,152,831
Safety and Feasibility of Pulsed Electric Field Ablation for Early-Stage Non-Small Cell Lung Cancer Prior to Surgical Resection.
Journal of surgical oncology
J Surg Oncol
131
8
10.1002/jso.28110
eng
2,025
6
null
2,025
3
28
[BACKGROUND AND METHODS] Surgery remains the standard of care for non-small cell lung cancer (NSCLC) but is applicable to ≤ 30% of patients. Pulsed Electric Fields (PEF) ablation uses short-duration, high-voltage electrical pulses to induce cell death without relying on thermal mechanisms. Safety findings are reported ...
Pulsed Electric Fields; ablation; histopathology; sensitive structures; tertiary lymphoid structures
0.741
136
Surgery; Medicine; Oncology
Medicine
2,024
40,152,415
Factors Predisposing to the Onset of Bipolar Disorder: A 30-Year Longitudinal Study.
Bipolar disorders
Bipolar Disord
27
4
10.1111/bdi.70026
eng
2,025
6
null
2,025
3
28
[OBJECTIVE] To examine the factors that predict the development of bipolar disorder in a population presenting with anxiety and depressive disorders. [METHOD] In a 30-year study, the Nottingham Study of Neurotic Disorder, the personality status, life events, service data, and early course of patients recruited to a ran...
bipolar disorder; prediction
1.312
145
Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience
2,024
40,152,156
Functional but Not Structural Brain Changes After Olfactory Training in Women With COVID-19-Associated Olfactory Dysfunction.
The Laryngoscope
Laryngoscope
135
6
10.1002/lary.32128
eng
2,025
6
null
2,025
3
28
[BACKGROUND] Olfactory training (OT) is a recommended treatment for olfactory loss and has proven effective in clinical contexts, yet its effects on the central-nervous system remain unclear. This study aimed to investigate the functional and structural brain changes in patients with post-viral olfactory loss undergoin...
COVID; MRI; olfactory loss; olfactory training; smell
1.029
183
Otorhinolaryngology
Medicine
2,024
40,151,024
Risk Stratification for Extranodal Extension in Head and Neck Cancers-Implication for Treatment Intensification.
Head neck
Head Neck
47
8
10.1002/hed.28144
eng
2,025
8
null
2,025
3
28
[BACKGROUND] Extranodal extension (ENE) is an important adverse prognostic indicator for head and neck cancers. However, ENE needs further risk stratification in terms of optimum cutoff for the extent of ENE and interaction with clinicopathological risk factors. [METHODS] Retrospective single-center study on patients w...
chemoradiotherapy; extranodal extension; head and neck cancer; lymph node; oral cancer; radiotherapy; squamous cell carcinoma
null
null
null
null
null
40,150,887
Predictive factors for the diagnosis of autoimmune pancreatitis using endoscopic ultrasound-guided tissue acquisition: a retrospective study in Japan.
Clinical endoscopy
Clin Endosc
58
3
10.5946/ce.2024.238
eng
2,025
5
null
2,025
3
28
[BACKGROUND/AIMS] The factors affecting the detection rate of lymphoplasmacytic sclerosing pancreatitis (LPSP) using endoscopic ultrasound-guided tissue acquisition (EUS-TA) in patients with type 1 autoimmune pancreatitis (AIP) have not been thoroughly studied. Therefore, we conducted a retrospective study to identify ...
Autoimmune pancreatitis; Fine needle biopsy
0.649
44
Gastroenterology; Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,150,598
Treatment of Pediatric Displaced Intraarticular Olecranon Fractures with Resorbable Poly-L-Lactic-Co-Glycolic Acid (PLGA) Pins and Polydioxanone (PDS) Loops.
Children (Basel, Switzerland)
Children (Basel)
12
3
10.3390/children12030316
eng
2,025
2
28
2,025
2
28
[BACKGROUND] Pediatric olecranon fractures, though rare, can be serious. Treatment varies by type and severity; displaced, intraarticular fractures usually need surgery, where biodegradable implants are emerging as an encouraging option to metal hardware. [METHODS] Our prospective, single-center, single-arm case series...
PDS; PLGA; elbow; fracture; implant; olecranon; pediatric; resorbable
0.674
56
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,150,479
Exploring Patient Awareness and the Feasibility of Mediation in Healthcare: A Pilot Study in Bulgaria.
Healthcare (Basel, Switzerland)
Healthcare (Basel)
13
6
10.3390/healthcare13060629
eng
2,025
3
14
2,025
3
14
[BACKGROUND/OBJECTIVES] The healthcare system is complex and emotionally charged, which frequently leads to conflicts between patients and healthcare providers as a result of inadequate communication and unmet patient expectations. This pilot study investigates patient awareness and the feasibility of mediation as an a...
alternative dispute resolution methods; healthcare conflict resolution; healthcare mediation
0.83
33
Health Policy
Medicine
2,024
40,149,361
Development of an Intratumoral Holmium Microsphere Injection Method in Ex Vivo Human Pancreatic Ductal Adenocarcinoma: A Preclinical Feasibility Study.
Cancers
Cancers (Basel)
17
6
10.3390/cancers17061028
eng
2,025
3
19
2,025
3
19
[BACKGROUND/OBJECTIVES] Patients diagnosed with pancreatic ductal adenocarcinoma (PDAC) have a poor prognosis. Local therapy may enhance tumor control and increase resectability. Intratumoral injection of radioactive holmium-166 microspheres presents a promising and minimally invasive treatment with multimodality imagi...
fundamental research; holmium microspheres; intratumoral injection; local therapy; microbrachytherapy; novel therapy; pancreatic cancer
1.462
157
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,149,338
Investigating Intensity and Percentage of p53 Nuclear Expression in Prostate Cancer: Findings from a Cohort of U.S. Military Veterans.
Cancers
Cancers (Basel)
17
6
10.3390/cancers17061004
eng
2,025
3
17
2,025
3
17
[BACKGROUND] Next-generation sequencing has revealed TP53 alterations in localized prostate cancer (PCa), suggesting growing clinical potential for p53 immunohistochemistry (IHC). Prior research supports the use of IHC for the detection of p53 overexpression to predict the presence of TP53 alterations known to be assoc...
African American; TP53; biomarker; immunohistochemistry; p53; progression; prostate cancer
1.462
157
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,149,008
Loss of OBSCN expression promotes bladder cancer progression but enhances the efficacy of PD-L1 inhibitors.
Cell bioscience
Cell Biosci
15
1
10.1186/s13578-025-01379-w
eng
2,025
3
27
2,025
3
27
[BACKGROUND] As the objective overall response rate to immune checkpoint inhibitors (ICIs) is less than 30% in late stage or metastatic bladder cancer (BLCA), elucidating the intrinsic mechanisms of immune evasion is of great importance for the discovery of predictive and prognostic biomarkers and the exploration of no...
OBSCN; Bladder cancer; Immune checkpoint inhibitor; Immunotherapy; Obscurin
null
null
null
null
null
40,148,850
Comparative efficacy and safety of etanercept and adalimumab in the treatment of polyarticular juvenile idiopathic arthritis.
BMC pediatrics
BMC Pediatr
25
1
10.1186/s12887-025-05594-9
eng
2,025
3
27
2,025
3
27
[OBJECTIVE] This study aims to evaluate the efficacy and safety of Etanercept and Adalimumab in the treatment of polyarticular juvenile idiopathic arthritis (pJIA). [METHODS] From Jan 2021 to Oct 2023, 66 pJIA patients were prospectively randomized into Etanercept (n = 33) and Adalimumab (n = 33) groups at our hospital...
Adalimumab; Efficacy; Etanercept; Polyarticularjuvenile idiopathic arthritis; Safety
0.734
106
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,198,974
Chronic dizziness in older adults: Disrupted sensorimotor EEG beta oscillations during postural instability.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Clin Neurophysiol
174
null
10.1016/j.clinph.2025.03.032
eng
2,025
6
null
2,025
3
27
[OBJECTIVE] Chronic dizziness is common in older adults, yet frequently occurs without a clear cause ('idiopathic dizziness'). Patients experience subjective unsteadiness with minimal objective imbalance, potentially related to small vessel disease. Here we examine the hypothesis that this syndrome is associated with d...
Aging; Balance; EEG; Small vessel disease; Vestibular
1.329
230
Neurology; Neurology; Physiology; Sensory Systems
Medicine; Neuroscience
2,024
40,198,913
Clinical, Operational, and Economic Benefits of a Digitally Enabled Wound Care Program in Home Health: Quasi-Experimental, Pre-Post Comparative Study.
JMIR nursing
JMIR Nurs
8
null
10.2196/71535
eng
2,025
4
8
2,025
4
8
[BACKGROUND] The demand for home health care and nursing visits has steadily increased, requiring significant allocation of resources for wound care. Many home health agencies operate below capacity due to clinician shortages, meeting only 61% to 70% of demand and frequently declining wound care referrals. Implementing...
AI; artificial intelligence; clinical outcomes; cost saving; digital wound care; healing time; home health care; operational efficiency; skilled nursing visits; wound assessment
1.1
12
Nursing
Nursing
2,024
40,198,524
Hepatic immune-related adverse event increased the overall survival of patients with malignancies treated with immune checkpoint inhibitors.
Hepatology international
Hepatol Int
null
null
10.1007/s12072-025-10825-3
eng
2,025
4
8
2,025
4
8
[BACKGROUND AND AIM] Associations between the occurrence of abnormal liver function tests, an immune-related adverse event (irAE) caused by immune checkpoint inhibitors (ICIs), and treatment efficacy are unclear. We investigated the association between the incidence of these hepatic irAE occurrences and treatment respo...
Aminotransferase; Bilirubin; Hepatic failure; Hepatic irAEs; ICI; Malignancy; Multi-disciplinary cooperation; Overall survival; Prothrombin time; irAEs
1.986
70
Hepatology
Medicine
2,024
40,198,508
Geographic origins, transmission hotspots, and drug resistance mutations of HIV-1 CRF08_BC in Zhejiang Province, China.
Infection
Infection
null
null
10.1007/s15010-025-02530-y
eng
2,025
4
8
2,025
4
8
[PURPOSE] To understand the geographic origins, transmission hotspots, and drug resistance mutations (DRMs) of HIV-1 CRF08_BC in Zhejiang Province, China. [METHODS] This study analyzed HIV-1 CRF08_BC pol sequences collected between 2020 and 2023. Bayesian inference was employed to investigate temporal epidemic trends, ...
CRF08_BC; DRM; Geographic origins; Phylodynamic; Transmission cluster
1.167
94
Infectious Diseases; Medicine; Microbiology
Medicine
2,024
40,198,270
Multimarker Assessment of B-Cell and Plasma Cell Subsets and Their Prognostic Role in the Colorectal Cancer Microenvironment.
Clinical cancer research : an official journal of the American Association for Cancer Research
Clin Cancer Res
31
12
10.1158/1078-0432.CCR-24-4083
eng
2,025
6
13
null
null
null
[PURPOSE] Although the association between cytotoxic T lymphocytes and favorable prognosis in colorectal cancer is well established, the prognostic significance of B lymphocytes remains more ambiguous. This study aimed to assess the characteristics and significance of various B-cell and plasma cell subsets in colorecta...
null
4.8
392
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,197,697
Trueness and Passivity of Digital and Conventional Implant Impressions in Edentulous Jaws: A Prospective Clinical Study.
Clinical implant dentistry and related research
Clin Implant Dent Relat Res
27
2
10.1111/cid.70022
eng
2,025
4
null
null
null
null
[AIM] To compare the linear and angular deviations of conventional implant (CI) and digital implant (DI) impression techniques in edentulous jaws with four or six implants. [MATERIALS AND METHODS] Twenty participants (12 men, 8 women; mean age 58.6 years) with complete edentulous maxillary (n = 8) or mandibular (n = 12...
accuracy; conventional impressions; digital impressions; framework passivity; implant dentistry
1.315
105
Dentistry; Oral Surgery
Dentistry
2,024
40,197,324
Association of diurnal temperature range and childhood asthma: a population-based cross-sectional study in a Tropical City, China.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-22470-4
eng
2,025
4
7
2,025
4
7
[BACKGROUND] Climate change has significantly impacted the diurnal temperature range (DTR), particularly in tropical regions of China, where DTR fluctuations are more frequent. While previous studies have primarily focused on the link between short-term DTR exposure and childhood asthma, there is limited information on...
Asthma; Children; Climate; Diurnal temperature range; Tropical regions
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,197,272
Critical analysis of macular hole repair techniques: a comprehensive systematic review and meta-analysis comparing internal limiting membrane flap and internal limiting membrane peeling for any size of macular hole.
BMC ophthalmology
BMC Ophthalmol
25
1
10.1186/s12886-025-04011-0
eng
2,025
4
7
2,025
4
7
[BACKGROUND] Macular holes (MHs) are a leading cause of visual impairment and blindness worldwide defined as a partial or full thickness anatomical defect in the fovea of the retina. ILM peeling is an effective surgical procedure to repair the defect. However, this approach lacks efficacy for larger macular holes. ILM ...
Internal limiting membrane peeling; Inverted internal limiting membrane flap technique; Macular hole; Meta-analysis
0.72
67
Medicine; Ophthalmology
Medicine
2,024
40,197,244
Obsessive-compulsive disorder and temporal lobe porencephaly: a case report.
BMC psychiatry
BMC Psychiatry
25
1
10.1186/s12888-025-06774-8
eng
2,025
4
7
2,025
4
7
[BACKGROUND] The functional and structural abnormalities of cortico-striato-thalamo-cortex have been reported to be associated with the neurobiological basis of obsessive-compulsive disorder (OCD). OCD can also occur in the striatum damaging after brain infarction, which is called OCD caused by physical diseases. The r...
Obsessive-compulsive disorder; Porencephaly; Temporal lobe
1.375
151
Psychiatry and Mental Health
Medicine
2,024
40,197,202
Development of Potential Pharmacological Targets to Normalize Gene Expression in Islets of Type 2 Diabetic Patients.
Current medicinal chemistry
Curr Med Chem
null
null
10.2174/0109298673352470250312082922
eng
2,025
4
7
2,025
4
7
[BACKGROUND] Type 2 diabetes (T2D) is a disease of high prevalence that is expected to continue increasing despite the pharmacological treatments available; in most cases, it is difficult to control. Therefore, more research on experimental drugs is necessary to propose better treatments. [OBJECTIVE] This study aimed t...
Type 2 diabetes; bioinformatics; experimental drugs; multi-omics; pancreas; pharmacology.
0.778
210
Biochemistry; Drug Discovery; Molecular Medicine; Organic Chemistry; Pharmacology
Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
2,024
40,197,163
Effect of indoor air quality on potential risk of obstructive sleep apnea: results from Korea National Health and Nutrition Examination Survey.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-22127-2
eng
2,025
4
7
2,025
4
7
[BACKGROUND] Using nationally representative data from the 2020-2021 Korea National Health and Nutrition Examination Survey, we examined associations between indoor air pollutant exposure and potential obstructive sleep apnea (OSA) risk, estimated by STOP-BANG questionnaire scores. [METHODS] We included 1,501 participa...
Formaldehyde; Indoor air quality; Obstructive sleep apnea; South Korea
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,197,063
Utilising tracking technology to reduce the financial and patient care impact of lost ear, nose and throat equipment.
Annals of the Royal College of Surgeons of England
Ann R Coll Surg Engl
null
null
10.1308/rcsann.2025.0015
eng
2,025
4
8
2,025
4
8
[INTRODUCTION] The effective treatment of a patient in a timely manner requires specialist equipment, including in ear, nose and throat (ENT) services, where orifices require careful inspection. Otoscopy, flexible nasendoscopy, peritonsillar abscess drainage and nasal cautery are all common practices and cannot be succ...
Costs; Efficiency; Equipment; Lost; Tracking
0.393
79
Surgery; Medicine
Medicine
2,024
40,196,975
New Classification System for Radially Deviated Thumb Polydactyly.
The Journal of hand surgery
J Hand Surg Am
null
null
10.1016/j.jhsa.2025.02.024
eng
2,025
4
8
2,025
4
8
[PURPOSE] Radially deviated thumb polydactyly (RDTP) is a risk factor for secondary deformities but lacks comprehensive characterization. We developed a new classification system for RDTP based on the preoperative radiographic appearance that should inform surgical approaches: (1) D-shaped, (2) bell-shaped, (3) radial-...
Classification system; preoperative radiography; radially deviated; reliability; thumb polydactyly
0.982
142
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
40,196,910
Smoking attitudes in patients referred to a city-wide urgent ENT head and neck cancer service: an exploratory study looking at current smokers.
The Journal of laryngology and otology
J Laryngol Otol
null
null
10.1017/S0022215125000131
eng
2,025
4
8
2,025
4
8
[OBJECTIVE] Smoking is a risk factor for head and neck cancer. Referral for suspected head and neck cancer can be an opportunity for reassessing smoking behaviour. This study examined attitudes towards smoking in patients referred urgently with suspected head and neck cancer. [METHOD] A total of 98 smokers were referre...
head and neck neoplasms; smoking; smoking cessation; tobacco use disorder
0.423
79
Medicine; Otorhinolaryngology
Medicine
2,024
40,196,881
Anal dilations following posterior sagittal anorectoplasty: Are they necessary in all patients?
Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica
Cir Pediatr
38
2
10.54847/cp.2025.02.15
eng
2,025
4
7
2,025
4
7
[INTRODUCTION] Anal dilations (AD) following posterior sagittal anorectoplasty (PSARP) can have a psychological impact on patients and caregivers. We present our long-term results after changing the postoperative AD protocol to improve patient selection and avoid unnecessary ADs. [MATERIAL AND METHODS] A retrospective ...
Anorectal malformations; Dilators; Postoperative strictures; Sagittal posterior anorectoplasty
0.245
16
Medicine
Medicine
2,024
40,195,601
Machine learning algorithms for diabetic kidney disease risk predictive model of Chinese patients with type 2 diabetes mellitus.
Renal failure
Ren Fail
47
1
10.1080/0886022X.2025.2486558
eng
2,025
12
null
2,025
4
7
[BACKGROUND] Diabetic kidney disease (DKD) is a common and serious complication of diabetic mellitus (DM). More sensitive methods for early DKD prediction are urgently needed. This study aimed to set up DKD risk prediction models based on machine learning algorithms (MLAs) in patients with type 2 DM (T2DM). [METHODS] T...
Machine learning; diabetes mellitus; diabetic kidney disease; forecasting; statistical models
0.84
69
Nephrology; Critical Care and Intensive Care Medicine; Medicine
Medicine
2,024
40,195,585
Risk prediction for acute kidney disease and adverse outcomes in patients with chronic obstructive pulmonary disease: an interpretable machine learning approach.
Renal failure
Ren Fail
47
1
10.1080/0886022X.2025.2485475
eng
2,025
12
null
2,025
4
7
[BACKGROUND] Little is known about acute kidney injury (AKI) and acute kidney disease (AKD) in patients with chronic obstructive pulmonary disease (COPD) and COPD mortality based on the acute/subacute renal injury. This study develops machine learning models to predict AKI, AKD, and mortality in COPD patients, utilizin...
Acute kidney disease; acute kidney injury; chronic obstructive pulmonary disease; machine learning; mortality; predictive model
0.84
69
Nephrology; Critical Care and Intensive Care Medicine; Medicine
Medicine
2,024
40,195,031
Correlation study of facial lipid profile differences and skin physiological characteristics in Chinese women aged 19-33 years.
International journal of cosmetic science
Int J Cosmet Sci
null
null
10.1111/ics.13065
eng
2,025
4
7
2,025
4
7
[BACKGROUND] Changes in the stratum corneum (SC) lipid profiles are associated with various skin diseases. Factors, including age, ethnicity, season and anatomical location, can influence the variations in SC lipid profiles. According to reports, the facial sebum of Chinese women peaks at age 20-30, accompanied by vari...
correlation analysis; lipidomics; physiological parameters; stratum corneum lipids
0.694
83
Chemistry; Colloid and Surface Chemistry; Dermatology; Drug Discovery; Pharmaceutical Science; Aging
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,195,030
Hand Grip Strength and Body Composition According to the Sarcopenic Obesity Guidelines: Impact on Postoperative Complications in Patients With Gastric Cancer.
World journal of surgery
World J Surg
49
6
10.1002/wjs.12581
eng
2,025
6
null
2,025
4
7
[BACKGROUND] The diagnosis of sarcopenic obesity (SO) in patients with gastric cancer has been inconsistent among studies examining postoperative complications because diagnostic methods have not been standardized. This study aimed to clarify the differences in the prevalence of obesity with and without low hand grip s...
body composition; gastric neoplasms; postoperative complications; risk factors; sarcopenic obesity
0.771
176
Surgery
Medicine
2,024
40,195,027
Evaluation of Federally Mandated Smoke-Free Housing Policy and Health Outcomes Among Adults Over the Age of 50 in Low-Income, Public Housing in New York City, 2015-2022.
Nicotine tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Nicotine Tob Res
null
null
10.1093/ntr/ntaf046
eng
2,025
4
8
2,025
4
8
[INTRODUCTION] Effective July 2018, the U.S. Department of Housing and Urban Development issued a rule requiring all public housing authorities to implement smoke-free housing (SFH) policies in their developments. We examined the differential impacts of SFH policy on hospitalizations for myocardial infarction (MI) and ...
null
null
null
null
null
null
40,194,967
Subclinical Atherosclerosis Risk Can Be Predicted in Female Patients With Systemic Lupus Erythematosus Using Metabolomic Signatures: An Observational Study.
Journal of the American Heart Association
J Am Heart Assoc
14
8
10.1161/JAHA.124.036507
eng
2,025
4
15
2,025
4
7
[BACKGROUND] Cardiovascular disease (CVD) is a leading cause of death in women with systemic lupus erythematosus (SLE) due to accelerated atherosclerosis that is not predicted by established CVD risk scores. This study aimed to develop, validate, and test a female-focused predictive atherosclerosis risk signature based...
SLE; cardiovascular disease risk; female; metabolomics; subclinical atherosclerosis
2.189
152
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,193,704
Reducing Excessive Screen Time Among Primary School-aged Children Through Caregivers' Parenting Behaviors: A Feasibility Pilot Study in China.
Journal of developmental and behavioral pediatrics : JDBP
J Dev Behav Pediatr
46
3
10.1097/DBP.0000000000001351
eng
2,025
4
2
2,025
4
2
[OBJECTIVE] Given the well-documented associations between excessive screen time (ST) and adverse health outcomes, this pilot study aimed to examine the applicability and effectiveness of a multicomponent intervention that combined strategies to enhance caregivers' screen-related parenting practices with efforts to cre...
China; children; health; parenting practices; screen time intervention
null
null
null
null
null
40,193,574
Intra-Arrest Transport and Neurological Outcomes in Out-of-Hospital Cardiac Arrest with Initial Shockable Rhythm Who Failed the First Defibrillation: A Nationwide Study in Limited Prehospital Advanced Cardiac Life Support (ACLS) Settings.
Prehospital emergency care
Prehosp Emerg Care
null
null
10.1080/10903127.2025.2489036
eng
2,025
4
29
2,025
4
29
[OBJECTIVES] Early hospital transport may benefit out-of-hospital cardiac arrest (OHCA) patients with shockable rhythms who are refractory to defibrillation, particularly in settings with limited advanced on-scene interventions. However, its impact in emergency medical service (EMS) systems with limited advanced cardia...
null
0.916
76
Emergency Medicine; Emergency Nursing
Medicine; Nursing
2,024
40,193,573
Low insulin-like growth factor-1 levels are associated with myocardial mechano-energetic efficiency in older individuals.
The Journal of clinical endocrinology and metabolism
J Clin Endocrinol Metab
null
null
10.1210/clinem/dgaf209
eng
2,025
4
7
2,025
4
7
[BACKGROUND AND AIMS] Altered myocardial mechano-energetic efficiency (MEE) is a significant predictor of cardiovascular events and heart failure. Among the potential pathophysiological factors underlying MEE impairment, insulin-like growth factor-1 (IGF-1) may be a plausible candidate due to its role in the cardiovasc...
cardiovascular risk; impaired fasting glucose; impaired glucose tolerance; insulin-like growth factor-1; myocardial mechano-energetic efficiency; type 2 diabetes
2.183
400
Biochemistry; Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,193,380
Deciphering insights into commercial Myrrh species authenticity from the psbA-trsnH genetic region.
PloS one
PLoS One
20
4
10.1371/journal.pone.0320731
eng
2,025
null
null
2,025
4
7
[OBJECTIVE] The genetic analysis, particularly focusing on the psbA-trnH region, aims to tackle the challenges linked to myrrh identification and improve quality control in medicinal and aromatic plant sectors. This process reveals the genetic diversity inherent in myrrh species, identifies adulterants, and assesses co...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
40,193,208
Comparison of Sarcopenia With Frailty and Area Deprivation Index for Predicting Postoperative Mortality and Complications in Thoracolumbar Trauma.
Clinical spine surgery
Clin Spine Surg
null
null
10.1097/BSD.0000000000001812
eng
2,025
4
7
2,025
4
7
[STUDY DESIGN] Retrospective analysis. [OBJECTIVE] To compare sarcopenia to frailty and socioeconomic deprivation as preoperative predictors of mortality and complications in thoracolumbar spine trauma. [SUMMARY OF BACKGROUND DATA] Sarcopenia is a progressive musculoskeletal disorder characterized by the loss of muscle...
area deprivation index; complications; frailty; mortality; revision; sarcopenia; socioeconomic status; spine trauma; thoracolumbar
0.774
45
Surgery; Neurology; Orthopedics and Sports Medicine
Medicine
2,024
40,193,193
Cladribine, idarubicin, and cytarabine (CLIA) for patients with relapsed and/or refractory acute myeloid leukemia: A single-center, single-arm, phase 2 trial.
Cancer
Cancer
131
8
10.1002/cncr.35840
eng
2,025
4
15
null
null
null
[BACKGROUND] The treatment of relapsed and/or refractory (R/R) acute myeloid leukemia (AML) remains challenging because of poor responses to chemotherapy. Efforts to improve outcomes have included the use of high-dose cytarabine in combination with nucleoside analogs, such as cladribine. The authors evaluated combined ...
acute myeloid leukemia (AML); chemotherapy; cladribine; clinical trial
2.947
349
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,192,877
Rate of advance care planning practice during the COVID-19 outbreak in Japan: a cross-sectional survey study.
Aging clinical and experimental research
Aging Clin Exp Res
37
1
10.1007/s40520-025-03004-9
eng
2,025
4
7
2,025
4
7
[BACKGROUND] Advance care planning (ACP) ensures that future care is provided during serious illness, considering an individual's wishes; it is particularly important for older adults. Regarding ACP practices during the coronavirus disease (COVID-19) outbreak, although there are reports on patients, reports on geriatri...
Advance care planning; COVID-19; Dementia; Geriatricians; Patients
1.144
95
Aging; Geriatrics and Gerontology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,192,346
Metabolism-Related Programmed Cell Death: Unveiling Prognostic Biomarkers, Immune Checkpoints, and Therapeutic Strategies in Ovarian Cancer.
Cancer investigation
Cancer Invest
43
3
10.1080/07357907.2025.2481436
eng
2,025
3
null
2,025
4
7
[BACKGROUND] Ovarian cancer (OC), the gynecologic malignancy with the poorest prognosis, is driven by metabolic reprogramming and dysregulated programmed cell death (PCD). However, their interplay and prognostic significance remain inadequately understood. [METHODS] Transcriptomic data from OC patients and healthy cont...
Metabolic reprogramming; Ovarian cancer; Programmed cell death
0.505
96
Medicine; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,192,324
Treatment patterns and associated outcomes among patients with HER2+ metastatic breast cancer in the United States: an observational cohort study.
The oncologist
Oncologist
30
4
10.1093/oncolo/oyae280
eng
2,025
4
4
null
null
null
[BACKGROUND] With treatment options for human epidermal growth factor receptor 2-positive (HER2+) metastatic breast cancer (mBC) expanding, updated assessments of contemporary treatment patterns and clinical outcomes are needed. This study aimed to conduct such an assessment using data from real-world oncology practice...
human epidermal growth factor receptor 2; metastatic breast cancer; survival; treatment patterns
2.329
199
Cancer Research; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,191,798
Non-linear relationship between the children's dietary inflammatory index and asthma risk: identifying a critical inflection point in US children and adolescents.
Frontiers in nutrition
Front Nutr
12
null
10.3389/fnut.2025.1538378
eng
2,025
null
null
2,025
3
21
[BACKGROUND] Asthma, a chronic respiratory disease, is influenced by diet, which plays a key role in its onset and progression. The Children's Dietary Inflammatory Index (C-DII) measures how diets impact inflammation in children and adolescents (6-19 years). The C-DII is a metric that quantifies the inflammatory potent...
adolescents; asthma risk; children; dietary inflammation; food intake
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
40,191,794
Association between alcohol consumption and allergic rhinitis in US adults.
Frontiers in nutrition
Front Nutr
12
null
10.3389/fnut.2025.1544889
eng
2,025
null
null
2,025
3
21
[INTRODUCTION] Increasing evidence suggests that alcohol consumption may be associated with allergic diseases. This cross-sectional analysis aimed to determine the correlation between alcohol consumption patterns and allergic rhinitis (AR) in US adults. [METHODS] A cross-sectional study was conducted involving 2,179 in...
NHANES; alcohol; alcohol consumption; allergic rhinitis; allergy
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
40,191,733
Microglia and brain macrophages are differentially associated with tumor necrosis in glioblastoma: A link to tumor progression.
Oncology research
Oncol Res
33
4
10.32604/or.2024.056436
eng
2,025
null
null
2,025
3
19
[BACKGROUND] Microglia and brain macrophages contribute significantly to the tumor microenvironment in highly malignant glioblastoma where they are considered important drivers of tumor progression. A better understanding of the role of the brain macrophages present in glioblastoma appears crucial for improving therape...
Bone marrow-derived macrophages (BMDM); CD163; Glioblastoma/glioma stem cells (GSCs); IBA1; Microglia; Multimodal whole slide analysis; Tumor microenvironment
0.915
78
Medicine; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,191,625
Application of a practical methodology for the selection of suitable value chains to produce circular fertilisers from secondary raw materials.
Open research Europe
Open Res Eur
5
null
10.12688/openreseurope.19506.2
eng
2,025
null
null
2,025
3
31
[BACKGROUND] The growing demand for food products, driven by a growing world population, has increased Europe's dependence on conventional fertilisers, which have a high impact on the environment. In the last decade, new circular fertiliser value chains have appeared as promising alternatives to conventional fertiliser...
Agriculture; bio-waste; circular fertilisers; compost; organic by-products; resource efficiency; sewage sludge; wastewater
0.376
14
Multidisciplinary
Multidisciplinary
2,024
40,191,550
Pathologically Tumor-free Resection Margin Distance as a Surrogate Parameter in Primary Vulvar Squamous Cell Cancer: Analysis of a Large Two-Center Patient Cohort.
Geburtshilfe und Frauenheilkunde
Geburtshilfe Frauenheilkd
85
4
10.1055/a-2508-8628
eng
2,025
4
null
2,025
2
20
[BACKGROUND] This study evaluated the role of tumor-free margin distances and other prognostic factors, including age, lymph-node metastases, lymphatic vessel invasion, and local recurrence, on the survival of patients with vulvar squamous cell carcinoma (VSCC) undergoing primary surgical treatment. [METHODS] A retrosp...
resection margins; squamous cell cancer; vulvar cancer
null
null
null
null
null
40,191,441
The Prognostic Yield of Admission Shock Index in Patients with ST-Segment Elevation Myocardial Infarction: SEMI-CI Study.
International journal of preventive medicine
Int J Prev Med
16
null
10.4103/ijpvm.ijpvm_43_24
eng
2,025
null
null
2,025
3
21
[BACKGROUND] Early identification of high-risk patients presenting with ST-segment elevation myocardial infarction (STEMI) helps prevent complications. The shock index (SI) is a bedside risk-stratification tool used in emergency departments. In this study, we aimed to assess the SI's predictive value for prognosticatin...
In-hospital mortality; MACE; STEMI; one-year mortality; shock index
0.607
60
Public Health, Environmental and Occupational Health
Medicine
2,024
40,191,238
Exploring the Use of Associative Analogy Teaching in BME Computer Courses in Medical University.
Advances in medical education and practice
Adv Med Educ Pract
16
null
10.2147/AMEP.S436882
eng
2,025
null
null
2,025
4
1
[PURPOSE] Current approaches to teaching Biomedical Engineering (BME)-related computer courses in medical universities often have unsatisfactory outcomes. A "Microcomputer Principles and Interface Technology" course was taken as a typical example to explore a new teaching method based on the idea of associative analogy...
associative analogy; biomedical engineering; computer course; medical university; microcomputer principles and interface technology
0.548
47
Education
Social Sciences
2,024
40,191,192
Effect of the gut microbiome, skin microbiome, plasma metabolome, white blood cells subtype, immune cells, inflammatory proteins, and inflammatory cytokines on asthma: a two-sample Mendelian randomized study and mediation analysis.
Frontiers in immunology
Front Immunol
16
null
10.3389/fimmu.2025.1436888
eng
2,025
null
null
2,025
3
21
[BACKGROUND] Asthma is a chronic inflammatory disorder arising from incompletely understood heterogenic gene-environment interactions. This study aims to investigate causal relationships among gut microbiota, skin microbiota, plasma metabolomics, white blood cells subtype, immune cells, inflammatory proteins, inflammat...
Mendelian randomization; asthma; gut microbiota; immune cells; inflammatory cytokines; inflammatory proteins; plasma metabolites; skin microbiota
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,190,568
Evaluating the Implementation of fan-beam CT-guided online adaptive re-planning in definitive cervical cancer radiotherapy.
Frontiers in oncology
Front Oncol
15
null
10.3389/fonc.2025.1509619
eng
2,025
null
null
2,025
3
21
[BACKGROUND] This study aims to investigate the feasibility of fan-beam computed tomography (FBCT)-guided online adaptive radiotherapy (oART) in radical radiotherapy for cervical cancer. [METHODS] Ten patients who underwent radical radiotherapy for cervical cancer were enrolled in this study. All patients received exte...
acute toxicity; cervical cancer; dosimetric distribution; fan-beam computed tomography (FBCT); image-guided radiotherapy (IGRT); online adaptive radiotherapy (oART)
1.075
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,190,258
NDRG1/2 as a prognostic predictive biomarker of cervical cancer and its correlation with immune infiltration.
Biomarkers in medicine
Biomark Med
19
9
10.1080/17520363.2025.2483495
eng
2,025
5
null
2,025
4
7
[BACKGROUND] Cervical cancer (CC) is a leading cause of cancer-related death in women. The N-myc down-stream regulatory gene (NDRG) family has an unclear prognostic role in CC. [METHODS] We analyzed NDRG mRNA and protein levels in CC using public databases. And NDRG1 expression was verified through immunohistochemistry...
NDRG family; cervical cancer; immune cell infiltration; prognosis; public databases
0.493
59
Biochemistry; Clinical Biochemistry; Drug Discovery
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,189,931
Imaging and Clinical Features of Nodular Pulmonary Amyloidosis.
Journal of thoracic imaging
J Thorac Imaging
null
null
10.1097/RTI.0000000000000830
eng
2,025
4
7
2,025
4
7
[PURPOSE] To investigate the clinical and computed tomography (CT) features of nodular pulmonary amyloidosis (NPA) to enhance our understanding of the disease and improve the ability to differentiate it from other similar conditions. [MATERIALS AND METHODS] A retrospective analysis was conducted on the clinical data, c...
Amyloidosis; Computed tomography; Pulmonary nodule
0.699
69
Pulmonary and Respiratory Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,189,075
Intraoperative Irrigation and Topical Antibiotic Use Fail to Reduce Early Periprosthetic Joint Infection Rates: A Michigan Arthroplasty Registry Collaborative Quality Initiative Study.
The Journal of arthroplasty
J Arthroplasty
40
8S1
10.1016/j.arth.2025.03.062
eng
2,025
8
null
2,025
4
5
[BACKGROUND] Periprosthetic joint infections remain a major complication in total joint arthroplasty. Tremendous efforts made intraoperatively to prevent periprosthetic joint infection during primary procedures include antiseptics or antibiotics in irrigation solutions. This study analyzed the incidence of postoperativ...
antibiotic; antiseptic; periprosthetic joint infection; total hip arthroplasty; total knee arthroplasty
1.951
171
Orthopedics and Sports Medicine
Medicine
2,024
40,188,957
Health economic burden of refractory and recurrent Clostridioides difficile infection in the inpatient setting of the German healthcare system - the IBIS Study.
The Journal of hospital infection
J Hosp Infect
160
null
10.1016/j.jhin.2025.03.011
eng
2,025
6
null
2,025
4
4
[BACKGROUND] Clostridioides difficile infections (CDIs) remain a prevalent and costly healthcare challenge, particularly affecting elderly, comorbid patients. Evidence on the health economic burden of CDI in Germany, particularly in refractory and recurrent patients is limited. [METHODS] The IBIS study was a non-interv...
Burden of Clostridioides difficile infection; Productivity costs; Prolonged hospitalization; Recurrent CDI; Refractory CDI; Resource costs for inpatient treatment
1.017
143
Infectious Diseases; Medicine; Microbiology
Medicine
2,024
40,188,877
Gonioscopy-Assisted Transluminal Trabeculotomy for Myocilin-Associated Juvenile Open-Angle Glaucoma: A Case Series of 8 Eyes Over 2.2 to 4.1 Years.
Ophthalmology. Glaucoma
Ophthalmol Glaucoma
null
null
10.1016/j.ogla.2025.03.011
eng
2,025
4
4
2,025
4
4
[OBJECTIVE] Mutations within the myocilin (MYOC) gene are the first known single-gene cause of both primary open-angle glaucoma and juvenile open-angle glaucoma (JOAG). Subsequent studies have shown these mutations cause trabecular meshwork dysfunction, resulting in markedly elevated intraocular pressures (IOPs) at you...
Juvenile open-angle glaucoma (JOAG); MYOC; Myocilin
1.372
27
Ophthalmology
Medicine
2,024
40,188,860
Comparative Assessment of Risk Score Performance in Ruptured Abdominal Aortic Aneurysm Repair Risk Stratification.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Eur J Vasc Endovasc Surg
null
null
10.1016/j.ejvs.2025.04.002
eng
2,025
4
4
2,025
4
4
[OBJECTIVE] Several risk scores are available to stratify the mortality risk of ruptured abdominal aortic aneurysm (rAAA) repair. This study compared the performance of seven risk scores found in the literature using the National Surgical Quality Improvement Program (NSQIP) and Vascular Quality Initiative (VQI) registr...
Calibration; Discrimination; Risk score; Ruptured abdominal aortic aneurysm
1.512
144
Cardiology and Cardiovascular Medicine; Surgery
Medicine
2,024
40,188,814
Impact of Fluid Management on Outcomes in Sequential Extracorporeal Support: A Post Hoc Analysis.
Blood purification
Blood Purif
null
null
10.1159/000545728
eng
2,025
4
4
2,025
4
4
[INTRODUCTION] Sepsis is a life-threatening condition characterized by dysregulated inflammatory responses, often leading to multiple organ dysfunction and high mortality rates. Continuous renal replacement therapy (CRRT) and extracorporeal blood purification therapies have emerged as vital adjuncts to manage fluid ove...
Continuous renal replacement therapy; Extracorporeal blood purification; Fluid balance; Hemodynamic stability; Septic shock; Ultrafiltration
0.545
72
Medicine; Nephrology; Hematology
Medicine
2,024
40,188,712
Child stunting, thinness, and their academic performance in Ethiopia: A longitudinal study.
Social science medicine (1982)
Soc Sci Med
373
null
10.1016/j.socscimed.2025.118050
eng
2,025
5
null
2,025
4
3
[BACKGROUND] The link between stunting, thinness, and academic performance in Ethiopia remains underexplored. The current study analyses a large and longitudinal dataset to estimate the relationship between thinness, stunting, and children's academic performance in Ethiopia. [METHOD] Data from the Young Lives Study, a ...
Academic performance; Child stunting; Ethiopia; Thinness
null
null
null
null
null
40,188,711
The mediating role of food insecurity in the relationship between income poverty and depressive symptoms and suicidal ideation: A nationwide study of Korean adults.
Social science medicine (1982)
Soc Sci Med
373
null
10.1016/j.socscimed.2025.117972
eng
2,025
5
null
2,025
3
18
[BACKGROUND] Income poverty has been linked to poor mental health. Food insecurity, a consequence of poverty, has been identified as a determinant of mental health. We explored the mediating role of food insecurity in the relationship between income poverty and mental health problems. [METHODS] This study utilized a na...
Food security; Hunger; Mediation analysis; Mental health; Public health
null
null
null
null
null
40,188,700
The impact of 12 weeks combined resistance and balance training on functional Sit-To-Stand muscle power in mobility limited older patients.
Gait posture
Gait Posture
120
null
10.1016/j.gaitpost.2025.03.025
eng
2,025
7
null
2,025
4
2
[BACKGROUND] Falls become more frequent with ageing. Improving balance and muscle strength has been shown to reduce the risk of falls in older patients, but the importance of muscle power is less investigated. [OBJECTIVE] To evaluate changes in functional Sit-to-Stand muscle power and the association with dynamic balan...
Aging; Dynamic balance; Falls; Frail; Muscle power; Physiotherapy
null
null
null
null
null
40,188,634
Low-dose tin-filtered computed tomography (CT) with iterative metal artifact reduction algorithm versus dual-energy CT for patients with lumbar metal implants.
European journal of radiology
Eur J Radiol
187
null
10.1016/j.ejrad.2025.112096
eng
2,025
6
null
2,025
4
4
[PURPOSE] This study aimed to evaluate a low-dose tin-filtered (LD Sn) CT protocol with iterative metal artifact reduction (iMAR) to reduce metal artifacts and radiation dose compared to dual-energy CT (DECT) with iMAR in patients with lumbar metal implants. [METHODS] The study included 70 patients, comprising 35 patie...
Dual-energy; Metal artifact reduction; Radiation dose; Spine; Tin filter
1.003
139
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,188,412
The Utilization of Specialist Palliative Care and Other Health Care Services at the End of Life Among Patients with Head and Neck Cancer: A Nationwide Cohort Study.
Oncology and therapy
Oncol Ther
13
2
10.1007/s40487-025-00335-5
eng
2,025
6
null
2,025
4
6
[INTRODUCTION] The end of life of patients with head and neck cancer (HNC) is plagued by significant morbidity and high symptom burden, emphasizing the need for palliative care. Our aim was to evaluate the utilization of health care services, including specialist palliative care (SPC), among patients with HNC at the en...
End of life; Head and neck cancer; Health care utilization; Palliative care; Specialist palliative care
null
null
null
null
null
40,188,128
Study on the effect of simulation-based case teaching method on the preclinical teaching of tooth defects restoration.
BMC medical education
BMC Med Educ
25
1
10.1186/s12909-025-07010-3
eng
2,025
4
5
2,025
4
5
[BACKGROUND] Clinical decision plays an important role in the prognosis of dental defect restoration. However, the current theoretical teaching and experimental teaching lack the training of clinical decision based on evidence-based medicine. Students have mastered theoretical knowledge and basic operating skills, they...
Medical humanity; Preclinical training; Situational-based education; Tooth defect; Treatment plan
0.947
107
Education; Medicine
Medicine; Social Sciences
2,024
40,188,045
The impact of external oblique intercostal block on early postoperative pain and recovery in patients undergoing J-shaped incisions for upper abdominal surgery: a single-center prospective randomized controlled study.
BMC anesthesiology
BMC Anesthesiol
25
1
10.1186/s12871-025-03030-0
eng
2,025
4
5
2,025
4
5
[BACKGROUND] The aim of this study was to investigate the effects of external oblique intercostal nerve block (EOIB) on early postoperative pain and recovery in patients undergoing J-shaped incision surgery in the upper abdomen. [METHODS] Patients aged 18-85 years, classified as ASA I-III, undergoing elective open uppe...
External oblique intercostal plane block; General surgery; Postoperative analgesia; Ultrasound-guided
0.753
58
Anesthesiology and Pain Medicine
Medicine
2,024
40,188,025
Clinical characteristics of active tuberculosis with pulmonary thromboembolism.
BMC pulmonary medicine
BMC Pulm Med
25
1
10.1186/s12890-025-03602-3
eng
2,025
4
5
2,025
4
5
[BACKGROUND] In this study, we summarized clinical characteristics in patients with active tuberculosis (ATB) complicated by pulmonary thromboembolism (PTE), to further determine the influencing factors of PTE in ATB patients. [METHODS] The study population consisted of ATB patients who were first seen and hospitalized...
Active tuberculosis; CTPA; High risk factor; Pulmonary thromboembolism; Venous thromboembolism
0.889
85
Pulmonary and Respiratory Medicine
Medicine
2,024
40,187,999
Red blood cell transfusion in canine and feline patients under general anaesthesia.
Veterinary anaesthesia and analgesia
Vet Anaesth Analg
52
3
10.1016/j.vaa.2025.02.014
eng
2,025
null
null
2,025
3
1
[OBJECTIVE] To describe a referral hospital population of dogs and cats receiving red blood cell (RBC) transfusions during general anaesthesia (GA). [STUDY DESIGN] Retrospective cohort study. [ANIMALS] Cats and dogs. [METHODS] Between 2016 and 2021, animals that received RBC products during GA were identified using cli...
canine; feline; general anaesthesia; red blood cell; transfusion
0.722
67
Veterinary
Veterinary
2,024
40,187,428
AI-driven analyzes of open-ended responses to assess outcomes of internet-based cognitive behavioral therapy (ICBT) in adolescents with anxiety and depression comorbidity.
Journal of affective disorders
J Affect Disord
381
null
10.1016/j.jad.2025.04.003
eng
2,025
7
15
2,025
4
3
[OBJECTIVE] Although patients prefer describing their problems using words, mental health interventions are commonly evaluated using rating scales. Fortunately, recent advances in natural language processing (i.e., AI-methods) yield new opportunities to quantify people's own mental health descriptions. Our aim was to e...
Artificial intelligence; Internet-based cognitive behavioral therapy; Mental health interventions; Natural language; Outcome assessment
2.121
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
40,187,226
In utero exposure to synthetic sex hormones and their multigenerational impact on neurodevelopmental disorders: Endocrine disruptors as neuroendocrine disruptors.
Journal of the neurological sciences
J Neurol Sci
472
null
10.1016/j.jns.2025.123471
eng
2,025
5
15
2,025
4
1
[BACKGROUND] Synthetic sex hormones, estrogens and/or progestogens, have been widely administered without sufficient long-term studies for decades to millions of pregnant women around the world and although most were banned in the 1970s and 1980s, some progestins continue to be prescribed. Psychiatric disorders, includ...
Estrogens; Health sciences; Multigenerational impact; Progestogens; Synthetic sex hormones
1.145
158
Neurology; Neurology
Medicine; Neuroscience
2,024
40,186,752
Obsessive-compulsive symptoms and traits in patients with burning mouth syndrome: a cross-sectional multicentric analysis.
Clinical oral investigations
Clin Oral Investig
29
4
10.1007/s00784-025-06293-6
eng
2,025
4
5
2,025
4
5
[OBJECTIVE] This study investigates the frequency and characteristics of obsessive-compulsive (OC) symptoms and Obsessive-Compulsive Personality Disorder (OCPD) in patients with Burning Mouth Syndrome (BMS). [BACKGROUND] Obsessive-Compulsive Disorder (OCD) is a chronic condition involving intrusive thoughts (obsessions...
Burning mouth syndrome; CPAS; Compulsive personality traits; OCI-R; Obsessive-Compulsive personality disorder; Obsessive-compulsive disorder
0.983
108
Dentistry
Dentistry
2,024
40,186,297
Short-term outcome following postoperative enhanced recovery implementation in patients with perforated peptic ulcer.
European journal of medical research
Eur J Med Res
30
1
10.1186/s40001-025-02432-7
eng
2,025
4
4
2,025
4
4
[OBJECTIVES] To evaluate the short-term outcome following postoperative enhanced recovery implementation in patients with perforated peptic ulcer. [METHODS] Quasi-experimental research design was utilized. Thirty patients received postoperative enhanced recovery after open surgical repair of perforated peptic ulcer com...
Outcome; Perforated peptic ulcer; Postoperative enhanced recovery
null
70
Medicine
Medicine
2,024
40,186,248
Heme oxygenase 1 confers gilteritinib resistance in FLT3-ITD acute myeloid leukemia in a STAT6-dependent manner.
Cancer cell international
Cancer Cell Int
25
1
10.1186/s12935-025-03757-3
eng
2,025
4
4
2,025
4
4
[BACKGROUND] Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. We previously discovered that heme oxygenase 1 (HO1) is crucial for chemoresistance in AML, but the detailed molecular mechanism of that remains unclear. [METHODS] RNA sequencing was conducted to assess transcriptomic changes...
Acute myeloid leukemia; FLT3-ITD mutation; Gilteritinib resistance; Heme Oxygenase 1; STAT6
1.5
90
Genetics; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,186,214
The effect of expanded access to mental health care on economic status of households with a person with a mental disorder in rural Ethiopia: a controlled before-after study.
International journal of mental health systems
Int J Ment Health Syst
19
1
10.1186/s13033-025-00668-8
eng
2,025
4
4
2,025
4
4
[BACKGROUND] Poverty and mental illness are strongly associated. The aim of this study was to investigate the economic impact of implementing a district level integrated mental healthcare plan for people with severe mental disorders (SMD) and depression compared to secular trends in the general population in a rural Et...
Controlled before-after study; Depression; Mental health interventions; Severe mental disorders; Task-shifting; Universal health coverage
1.563
58
Health Policy; Psychiatry and Mental Health; Public Health, Environmental and Occupational Health
Medicine
2,024
40,186,159
Changes in network centrality of anxiety and depression symptoms associated with childhood trauma among Chinese college students.
BMC psychiatry
BMC Psychiatry
25
1
10.1186/s12888-025-06793-5
eng
2,025
4
4
2,025
4
4
[BACKGROUND] Childhood trauma is strongly linked to anxiety and depression, significantly increasing the risk of negative outcomes in adulthood. This study employed network analysis to investigate the complex interplay of anxiety and depression symptoms among Chinese college students, focusing on identifying the core s...
Anxiety; Childhood trauma; College students; Depression; Network analysis
1.375
151
Psychiatry and Mental Health
Medicine
2,024
40,186,043
Inflammatory bowel disease in paediatric rheumatological diseases.
Clinical rheumatology
Clin Rheumatol
44
5
10.1007/s10067-025-07424-w
eng
2,025
5
null
2,025
4
4
[INTRODUCTION] Rheumatological diseases (RD) in childhood are systemic diseases that occur on the basis of auto-immunity or inflammation, and they can be accompanied by inflammatory bowel disease (IBD). When there is no knowledge of this association, the treatments applied may not be sufficient and/or treatments given ...
Chronic nonbacterial osteomyelitis; Familial Mediterranean fever; Inflammatory bowel disease; Juvenile idiopathic arthritis; Rheumatological diseases
0.855
104
Medicine; Rheumatology
Medicine
2,024
40,185,666
Remote ischaemic preconditioning and survival in noncardiac surgery: a meta-analysis of randomised trials.
British journal of anaesthesia
Br J Anaesth
134
5
10.1016/j.bja.2025.02.023
eng
2,025
5
null
2,025
4
3
[BACKGROUND] Remote ischaemic preconditioning (RIPC) is an intervention involving brief periods of limb ischaemia to protect remote organs from subsequent ischaemic injury. Although evidence exists on the beneficial effects of RIPC on biomarkers, its effect on survival is unknown. We performed a meta-analysis of random...
acute kidney injury; anaesthesia; meta-analysis; mortality; noncardiac surgery; organ protection; remote ischaemic preconditioning (RIPC)
2.36
222
Anesthesiology and Pain Medicine
Medicine
2,024
40,185,644
Oncological and functional outcomes after sacrectomy for colorectal cancer: A systematic review.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Colorectal Dis
27
4
10.1111/codi.70083
eng
2,025
4
null
null
null
null
[AIM] Worldwide, of all cancers, colorectal cancer has the fourth highest rate of mortality. Curative treatment for locally advanced or recurrent rectal cancer can require extended resections with sacrectomy, but this sugery can have major consequences for patients. The aim of this study was to investigate the oncologi...
colorectal cancer; functional outcomes; oncological outcomes; sacrectomy
1.005
110
Gastroenterology
Medicine
2,024
40,185,289
Assessment of ventilation heterogeneity and particle deposition in asthmatics using combined SPECT/CT imaging and computational modeling approaches.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Eur J Pharm Sci
209
null
10.1016/j.ejps.2025.107093
eng
2,025
6
1
2,025
4
2
[PURPOSE] This study investigated asthma phenotypes and their associations with ventilation heterogeneity and particle deposition by utilizing Single-Photon Emission Computed Tomography (SPECT) imaging, quantitative Computed Tomography (qCT) imaging-based subgrouping, and a whole-lung computational model. [MATERIALS AN...
Asthma; CFPD; CT; Clusters; Particle deposition; SPECT; Ventilation heterogeneity
0.827
170
Pharmaceutical Science
Pharmacology, Toxicology and Pharmaceutics
2,024
40,184,812
Plasma and urine metabolomics for the identification of diagnostic biomarkers for sulfur mustard-induced lung injury.
International immunopharmacology
Int Immunopharmacol
154
null
10.1016/j.intimp.2025.114515
eng
2,025
5
8
2,025
4
4
[BACKGROUND] Sulfur mustard (SM) is a highly lethal chemical warfare agent that induces severe health complications in exposed individuals. Gaining insights into the metabolic changes caused by SM exposure is essential for understanding its underlying mechanisms and developing effective diagnostic and therapeutic inter...
HNMR; Metabolomics; Plasma; Sulfur mustard; Urine
1.239
155
Pharmacology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,184,787
The number and frequency of mucosal-associated invariant T (MAIT), γδ T, and innate lymphoid cells (ILCs) altered in patients with type I Gaucher disease.
Human immunology
Hum Immunol
86
3
10.1016/j.humimm.2025.111302
eng
2,025
5
null
2,025
4
3
[INTRODUCTION] Gaucher disease (GD) is a rare lysosomal storage disease caused by mutations in the Glucocerebrosidase (GBA) gene. The innate immunopathology of GD beyond macrophage involvement is not well characterized. In the current study, the changes in ILC subsets, γδ T and MAIT cells, TNF-α and IFN-γ cytokine leve...
Cytokines; Gaucher disease; ILC cells; MAIT cells
0.895
105
Immunology; Immunology and Allergy; Medicine
Immunology and Microbiology; Medicine
2,024
40,184,733
Self-reported cognitive function in older breast cancer survivors after chemotherapy treatment.
Breast (Edinburgh, Scotland)
Breast
81
null
10.1016/j.breast.2025.104468
eng
2,025
6
null
2,025
4
1
[PURPOSE] This study evaluated self-reported cognitive function in older breast cancer survivors and its association with prior chemotherapy. [MATERIALS AND METHODS] Breast cancer survivors aged 65-years and older, diagnosed 2012-2013, with local and regional stage disease, were identified through the linked Texas Canc...
Breast cancer survivor; Chemotherapy treatment; Cognitive impairment; Geriatric oncology; Health outcomes; Survey linked-data
2.348
106
Cancer Research; Medicine; Oncology; Surgery
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,184,567
Phase I Study of Subcutaneous Rituximab Hyaluronidase Combined With CHOP Chemotherapy for the Treatment of Diffuse Large B-Cell Lymphoma in Uganda.
JCO global oncology
JCO Glob Oncol
11
null
10.1200/GO-24-00489
eng
2,025
4
null
2,025
4
4
[PURPOSE] Patients with diffuse large B-cell lymphoma (DLBCL) who are treated in low-resource settings have inferior outcomes compared with those in high-resource settings. Rituximab, an anti-CD20 monoclonal antibody, when combined with chemotherapy, improves overall survival (OS) for DLBCL. However, in part due to the...
null
null
null
null
null
null
40,184,367
Genetic, clinical, lifestyle and sociodemographic risk factors for head and neck cancer: A UK Biobank study.
PloS one
PLoS One
20
4
10.1371/journal.pone.0318889
eng
2,025
null
null
2,025
4
4
[INTRODUCTION] Despite a steady decline in tobacco smoking, head and neck cancer (HNC) incidence rates are on the rise. Therefore, novel risk factors for HNC are needed to identify at-risk patients at an early stage. Here, we used genetic, clinical, lifestyle, and sociodemographic data from UK Biobank (UKB) to evaluate...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
40,184,066
Perspectives on AI and Novel Technologies Among Older Adults, Clinicians, Payers, Investors, and Developers.
JAMA network open
JAMA Netw Open
8
4
10.1001/jamanetworkopen.2025.3316
eng
2,025
4
1
2,025
4
1
[IMPORTANCE] Artificial intelligence (AI) and novel technologies, such as remote sensors, robotics, and decision support algorithms, offer the potential for improving the health and well-being of older adults, but the priorities of key partners across the technology innovation continuum are not well understood. [OBJECT...
null
3.546
154
Medicine
Medicine
2,024
40,183,935
Adamantinomatous craniopharyngioma stone: is it a tumor?
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Childs Nerv Syst
41
1
10.1007/s00381-025-06798-1
eng
2,025
4
4
2,025
4
4
[INTRODUCTION] Adamantinomatous craniopharyngioma (ACP) is a benign epithelial tumor of the sellar and suprasellar region, and in children, it usually presents with cysts and calcifications. [METHODS] In this study, ACP samples were collected, and after enzymatic digestion of the calcified component of these tumors, wh...
Craniopharyngioma; MRI; Primary culture; Xenograft model
0.478
100
Pediatrics, Perinatology and Child Health; Medicine; Neurology
Medicine
2,024
40,183,588
Perioperative Nurses' Experience of Working With Persons Living With Dementia.
Research in gerontological nursing
Res Gerontol Nurs
18
4
10.3928/19404921-20250331-02
eng
2,025
null
null
2,025
4
7
[PURPOSE] To explore the experiences of nurses working with persons living with dementia (PLWD) in perioperative settings. [METHOD] A study using qualitative description methodology was conducted. We interviewed 20 nurses working on four units in an academic medical center. Conventional content analysis was used to ana...
null
0.547
33
Health Policy; Nursing; Geriatrics and Gerontology; Gerontology
Medicine; Nursing
2,024
40,183,453
Soluble Triggering Receptors on Myeloid Cells-1 Could Be a Potential Biomarker for Disease Activity in Familial Mediterranean Fever.
Journal of clinical laboratory analysis
J Clin Lab Anal
39
8
10.1002/jcla.70027
eng
2,025
4
null
2,025
4
4
[OBJECTIVES] Familial Mediterranean Fever (FMF) is an autoinflammatory disease. We aimed to investigate serum soluble Triggering Receptor Expressed on Myeloid Cells-1 and 2 (sTREM-1 and sTREM-2) levels in patients with FMF during both attack and attack-free periods and their relationship with disease activity. [METHODS...
auto inflammation; biomarker; familial mediterranean fever
0.738
67
Medical Laboratory Technology; Biochemistry; Clinical Biochemistry; Hematology; Microbiology; Public Health, Environmental and Occupational Health; Immunology and Allergy
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,024
40,183,105
Minding the gap. Drug-related problems among breastfeeding women.
Frontiers in pharmacology
Front Pharmacol
16
null
10.3389/fphar.2025.1542269
eng
2,025
null
null
2,025
3
13
[INTRODUCTION] Drug-related problems (DRPs) are a significant concern in many patient populations, including breastfeeding women. This study aimed to identify and characterize those problems in a group of breastfeeding women seeking specialized pharmaceutical care. [MATERIALS AND METHODS] A prospective observational st...
breastfeeding; drug-related problems; lactation; medication-related problems; pharmaceutical care; polypharmacy
1.22
175
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,182,884
Evaluation of a Multispecialty Mobile Health App: Pilot Study.
Journal of hand surgery global online
J Hand Surg Glob Online
7
2
10.1016/j.jhsg.2024.12.003
eng
2,025
3
null
2,025
1
27
[PURPOSE] Educational mobile apps have been studied in multiple surgical disciplines, evaluating a wide range of possible benefits with varying success in improving overall quality of life after surgery. We hypothesize that utilization of a mobile health app in the perioperative setting will be easy to use and will imp...
Application; Hand surgery; Health; Mobile; Pilot study
0.474
11
Rehabilitation; Surgery; Orthopedics and Sports Medicine
Medicine
2,024
40,182,852
Management of concurrent severe COVID-19 pneumonia and antibody-mediated rejection following kidney transplantation: a case report.
Frontiers in medicine
Front Med (Lausanne)
12
null
10.3389/fmed.2025.1521785
eng
2,025
null
null
2,025
3
13
[BACKGROUND] Due to its high mutation rate, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recurrently emerged worldwide in recent years, leading to an increased incidence of rejection following kidney transplantation and a worsened prognosis for recipients. The management of the concomitant occurrenc...
ABMR; IVIG; PE; SARS-CoV-2; kidney transplantation
0.962
102
Medicine
Medicine
2,024
40,182,823
Efficiency, cytotoxicity, and survivability evaluation of Salmonella phage cocktail against Salmonella derived from broiler sources.
Veterinary world
Vet World
18
2
10.14202/vetworld.2025.475-483
eng
2,025
2
null
2,025
2
26
[BACKGROUND AND AIM] Salmonella is a leading cause of foodborne illnesses worldwide, often linked to poultry products. Antibiotic resistance among Salmonella strains has increased the need for alternative decontamination strategies, such as bacteriophage (phage) therapy. This study evaluates the lytic efficiency, cytot...
Salmonella; antibiotic resistance; bacteriophage therapy; food safety; phage cocktail; poultry production
0.541
56
Veterinary
Veterinary
2,024
40,182,655
A Community Reintegration Model for Persons With Traumatic Spinal Cord Injury in South Africa: Process and Outcomes.
Advances in rehabilitation science and practice
Adv Rehabil Sci Pract
14
null
10.1177/27536351251326797
eng
2,025
null
null
2,025
4
3
[BACKGROUND] Traumatic spinal cord injury impacts physical functioning, independence, and quality of life. The high incidence rate of 75.6 per million in South Africa indicate the crucial role of successful community reintegration. Despite South African's policy emphasizing comprehensive rehabilitation of persons with ...
Community reintegration; South Africa; integration; participation; programs; rehabilitation; spinal cord injury; traumatic spinal cord injury
null
null
null
null
null
40,182,573
Urinary transforming growth factor beta-1 levels correlate with the effect of renorrhaphy on functional outcomes post-laparoscopic partial nephrectomy: A pilot-study.
Arab journal of urology
Arab J Urol
23
2
10.1080/20905998.2024.2432702
eng
2,025
null
null
2,024
11
25
[PURPOSE] Preservation of functional renal parenchyma is one of the main targets of partial nephrectomy. We investigated the effects of suture on renal parenchyma in tumor bed and on short-term renal function. [MATERIALS AND METHODS] Patients with unilateral cT1 renal masses candidate for laparoscopic partial nephrecto...
Functional outcome; fibrosis; healing; partial nephrectomy; renal cell carcinoma; tumor bed
0.546
34
Urology
Medicine
2,024
40,182,571
Robot-assisted partial nephrectomy in complex renal tumors using the Versius platform: An initial but promising experience.
Arab journal of urology
Arab J Urol
23
2
10.1080/20905998.2024.2442268
eng
2,025
null
null
2,024
12
16
[BACKGROUND AND OBJECTIVES] The widespread utilization of robotic surgeries in urology encouraged several teams to explore the option of performing robot-assisted partial nephrectomy (RAPN), taking advantage of its magnified stereoscopic vision and the articulating instruments that facilitate tumor resection and the re...
Robotic; Versius platform; nephron-sparing surgery; partial nephrectomy
0.546
34
Urology
Medicine
2,024
40,182,450
Comparing the Clinical and Microbiological Effects of Antibacterial-Coated Vicryl Suture and Non-Coated Vicryl Suture after Minor Oral Surgical Procedures.
Journal of maxillofacial and oral surgery
J Maxillofac Oral Surg
24
2
10.1007/s12663-024-02249-7
eng
2,025
4
null
2,024
6
21
[BACKGROUND AND OBJECTIVE] Surgical site infections are among the most common nosocomial infections, potentially leading to serious complications after surgical interventions. In intraoral surgical procedures, sutures are exposed to various bacterial species, raising the question of whether antibacterial-coated suture ...
Surgical site infection; Suture comparison; Vicryl; Vicryl Plus
0.371
36
Oral Surgery; Otorhinolaryngology; Surgery
Dentistry; Medicine
2,024
40,182,297
Biologic Response With and Without Acellular Dermal Matrix in Breast Reconstruction.
Plastic and reconstructive surgery. Global open
Plast Reconstr Surg Glob Open
13
4
10.1097/GOX.0000000000006671
eng
2,025
4
null
2,025
4
2
[BACKGROUND] Acellular dermal matrices (ADMs) are biologic meshes commonly used in implant-based breast reconstruction (IBBR) procedures to provide implant support and coverage. Although the etiology is not well understood, increasing preclinical and clinical evidence suggest that ADMs may help prevent capsular contrac...
null
0.676
57
Surgery
Medicine
2,024
40,182,255
Ultrasonography of lateral elbow pain through a weighted varus flexion position contributes to detect minor instabilities.
JSES international
JSES Int
9
2
10.1016/j.jseint.2024.11.003
eng
2,025
3
null
2,024
11
28
[BACKGROUND] Recent evidence indicates that lateral elbow pain may not stem solely from extra-articular or tendon-related sources, but rather be part of a multifactorial process that also involves intra-articular factors. Therefore, diagnosis of minor elbow instability is often delayed, waiting for conservative measure...
Diagnostic evaluation; Elbow instability; Epicondylitis; HELP US test; Recalcitrant lateral elbow pain; Varus stress
0.822
28
Surgery; Orthopedics and Sports Medicine
Medicine
2,024
40,182,252
Atraumatic elbow avascular necrosis in the adult is rare, multifocal, and associated with systemic corticosteroid use.
JSES international
JSES Int
9
2
10.1016/j.jseint.2024.10.008
eng
2,025
3
null
2,024
11
14
[BACKGROUND] Atraumatic avascular necrosis (AVN) of the elbow is a rare diagnosis with little literature describing features of this pathology. The purpose of this study is to investigate atraumatic elbow AVN in adults, with a focus on the anatomic distribution of AVN within skeletally mature elbows. [METHODS] A retros...
Avascular necrosis; Elbow; Elbow arthroscopy; Magnetic resonance imaging; Radiograph; Steroids
0.822
28
Surgery; Orthopedics and Sports Medicine
Medicine
2,024
40,181,869
Gender and personal safety sensitization in schools: A qualitative inquiry into response practices to children's disclosures of sexual abuse.
Indian journal of psychiatry
Indian J Psychiatry
67
2
10.4103/indianjpsychiatry.indianjpsychiatry_543_24
eng
2,025
2
null
2,025
2
19
[BACKGROUND] Schools provide opportunities to educate children on health and safety and encourage disclosures of difficult experiences. Policies and response mechanisms for disclosures are critical in the impact of preventive programs. [AIM] To understand school policies and practices for disclosures of child sexual ab...
Adolescence; child; child sexual abuse; disclosures; school-based programs
0.518
58
Psychiatry and Mental Health
Medicine
2,024
40,181,594
The effectiveness and safety of therapies for hepatocellular carcinoma with tumor thrombus in the hepatic vein, inferior vena cave and/or right atrium: a systematic review and single-arm meta-analysis.
Expert review of anticancer therapy
Expert Rev Anticancer Ther
25
5
10.1080/14737140.2025.2489651
eng
2,025
5
null
2,025
4
6
[BACKGROUND] This review evaluates the efficacy and safety of therapies for hepatocellular carcinoma (HCC) with hepatic vein tumor thrombus (HVTT), inferior vena cava tumor thrombus (IVCTT), and/or right atrium tumor thrombus (RATT). [RESEARCH DESIGN AND METHODS] A systematic review of PubMed, EMBASE, Cochrane Library,...
Heart; hepatectomy; hepatic vein; hepatocellular carcinoma; inferior vena cava; radiotherapy; targeted therapy; thrombectomy
0.926
88
Oncology; Pharmacology
Medicine
2,024
40,181,447
Cell-type-specific subtyping of epigenomes improves prognostic stratification of cancer.
Genome medicine
Genome Med
17
1
10.1186/s13073-025-01453-5
eng
2,025
4
3
2,025
4
3
[BACKGROUND] Most molecular classifications of cancer are based on bulk-tissue profiles that measure an average over many distinct cell types. As such, cancer subtypes inferred from transcriptomic or epigenetic data are strongly influenced by cell-type composition and do not necessarily reflect subtypes defined by cell...
Cancer; Cell-type deconvolution; Clinical outcome; Clustering; DNA methylation
5.078
133
Genetics; Genetics; Molecular Biology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024