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40,209,346
Effects of tea polyphenols and tea polysaccharides on improving nonylphenol-induced depression-like behavior, monoamine neurotransmitter disorder, and neuronal pyroptosis.
Ecotoxicology and environmental safety
Ecotoxicol Environ Saf
295
null
10.1016/j.ecoenv.2025.118166
eng
2,025
4
15
2,025
4
10
[BACKGROUND] Exposure to nonylphenol (NP) has been linked to depressive-like behaviors, while tea consumption is associated with a reduced risk of depression. This study investigates and compares the effects of tea polyphenols (TPs) and tea polysaccharides (TPSs) in alleviating NP-induced depressive-like behaviors, foc...
Neuronal apoptosis; Neurotransmitter; Nonylphenol; Tea polyphenol; Tea polysaccharide
1.553
197
Health, Toxicology and Mutagenesis; Medicine; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,024
40,208,488
Mitomycin C augmented canalicular silicone intubation versus external dacryocystorhinostomy in primary acquired nasolacrimal duct obstruction: a retrospective study.
International ophthalmology
Int Ophthalmol
45
1
10.1007/s10792-025-03445-1
eng
2,025
4
10
2,025
4
10
[PURPOSE] Given the improvement in the instruments and techniques, novel surgical interventions emerged to avoid osteotomy from the gold standard dacryocystorhinostomy (DCR) for treating primary acquired nasolacrimal duct obstruction (NLDO). This study compares external dacryocystorhinostomy versus canalicular silicone...
Canalicular silicone intubation; Dacryocystorhinostomy; Mitomycin C; Nasolacrimal duct obstruction
0.642
57
Ophthalmology
Medicine
2,024
40,208,484
The GPR4 antagonist NE 52-QQ57 prevents ox-LDL-induced cellular senescence by promoting the expression of SIRT1.
Genes genomics
Genes Genomics
47
6
10.1007/s13258-024-01610-x
eng
2,025
6
null
2,025
4
10
[BACKGROUND] Cell senescence-associated endothelia dysfunction is a vital point in the pathological progression of atherosclerosis (AS). G-protein coupled receptor 4 (GPR4) is a proton-sensing receptor involved in developing endothelial dysfunction. [OBJECTIVE] In this study, we investigated the protective role of NE 5...
Atherosclerosis; Cell senescence; Endothelial dysfunction; GPR4; SIRT1
null
null
null
null
null
40,208,181
Clinical study on the prevention of deep vein thrombosis in patients with external fixation of lower limb fractures using an automatic ankle pump movement ceramic moxibustion rehabilitation device.
Expert review of hematology
Expert Rev Hematol
18
5
10.1080/17474086.2025.2492226
eng
2,025
null
null
2,025
4
15
[BACKGROUND] This study aims to observe the clinical effect of an automatic ankle pump ceramic moxibustion rehabilitation device in preventing deep vein thrombosis (DVT) in patients with external fixation of lower limb fractures. [RESEARCH DESIGN AND METHODS] This prospective, single-center, double-blind randomized con...
coagulation function; deep vein thrombosis; external fixation; lower limb fractures
null
null
null
null
null
40,207,537
Effect of Bicuspid Versus Tricuspid Aortic Valve Morphology on the Fate of the Ascending Aorta.
Journal of the American Heart Association
J Am Heart Assoc
14
8
10.1161/JAHA.124.038013
eng
2,025
4
15
2,025
4
10
[BACKGROUND] Bicuspid aortic valves are associated with ascending aortic pathology, but their impact on long-term outcomes, including aortic growth and adverse events, remains unclear. [METHODS AND RESULTS] This prospective cohort-study included adult patients undergoing aortic valve surgery or ascending aortic surgery...
adverse aortic events; ascending aortic aneurysm; bicuspid aortic valve
2.189
152
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,207,219
CD14[+] monocytes: the immune communication hub in early vasculitis symptoms of Kawasaki disease.
Frontiers in immunology
Front Immunol
16
null
10.3389/fimmu.2025.1557231
eng
2,025
null
null
2,025
3
26
[BACKGROUND] Kawasaki Disease (KD) is an acute systemic vasculitis syndrome predominantly affecting children, with a propensity to induce coronary artery lesions. Aberrant immune activation and cytokines cascade reactions are involved in its pathogenesis. The aim of this study is to investigate the changes in immune ce...
CD14 + monocytes; Kawasaki disease; cell communication; single-cell sequencing
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,207,198
Trends in pancreatic cancer incidence, prevalence, and survival outcomes by histological subtypes: a retrospective cohort study.
Gastroenterology report
Gastroenterol Rep (Oxf)
13
null
10.1093/gastro/goaf030
eng
2,025
null
null
2,025
4
9
[BACKGROUND] Pancreatic cancer (PC) is a heterogeneous disease with various histological and molecular subtypes. This study aimed to provide updated epidemiological estimates, survival outcomes, and treatment information for PC based on histological subtypes in the USA. [METHODS] Data from the US Cancer Statistics and ...
Joinpoint; incidence; pancreatic cancer; prevalence; survival
0.899
48
Gastroenterology
Medicine
2,024
40,207,127
Unveiling the dynamics of team cognition in emergency response teams.
Frontiers in psychology
Front Psychol
16
null
10.3389/fpsyg.2025.1534224
eng
2,025
null
null
2,025
3
26
[BACKGROUND] Effective emergency response in various industries depends on the synergy between team coordination and cognitive abilities. Industries should prioritize investing in the development of team cognition to improve readiness and ensure swift, effective responses to emergencies and crises. This study aimed to ...
emergency response team; meta-synthesis; modeling; team cognition; weighting
0.872
212
Psychology
Psychology
2,024
40,206,825
New insights into chronic ankle instability: an in vivo evaluation of three-dimensional motion and stability of the ankle joint complex.
Frontiers in bioengineering and biotechnology
Front Bioeng Biotechnol
13
null
10.3389/fbioe.2025.1556291
eng
2,025
null
null
2,025
3
26
[INTRODUCTION] Chronic ankle instability (CAI) is generally associated with repetitive ankle sprains with concomitant ligament injuries and abnormal joint motion, which affects the stability of the joint. This study aims to quantify and compare the 3D motion differences in the ankle joint complex (AJC) during walking b...
ankle kinematics; biomechanics; biplanar radiography; chronic ankle instability; ground reaction force
0.974
119
Biomedical Engineering; Biotechnology; Histology; Bioengineering
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Engineering; Medicine
2,024
40,206,379
In Vitro Assessment of Anthelmintic Activities of AgO Nanoparticle against Liver Fluke Dicrocoelium dendriticum.
Iranian journal of parasitology
Iran J Parasitol
20
1
10.18502/ijpa.v20i1.18103
eng
2,025
null
null
null
null
null
[BACKGROUND] Dicrocoeliasis is an important helminthic zoonosis reported from many parts of the world. Due to low-performance medications, drug delivery is a great challenge in improving the treatment of this liver fluke infection. We aimed to determine the anthelmintic properties of Nanosilver oxide (AgO) against Dicr...
AgO nanoparticle; Closantel; Dicrocoelium dendriticum; Scanning electron microscopy
null
null
null
null
null
40,206,295
Risk factors for failing endotracheal extubation in neurocritical patients: a retrospective cohort study.
Frontiers in neurology
Front Neurol
16
null
10.3389/fneur.2025.1562454
eng
2,025
null
null
2,025
3
26
[OBJECTIVE] To identify risk factors of failing endotracheal extubation among neurocritical care patients with endotracheal intubation for more than 48 h and passing the autonomous breathing test (SBT) and establish a prediction model accordingly. [METHODS] This study included the clinical data of patients who received...
Glasgow Coma Scale; airway control; endotracheal extubation; neurocritical care; risk factors
0.993
118
Neurology; Neurology
Medicine; Neuroscience
2,024
40,206,261
Transcriptional profiling of milk fat synthesis in mammary gland of dairy cows with different forage quality using RNA sequencing.
Frontiers in veterinary science
Front Vet Sci
12
null
10.3389/fvets.2025.1469169
eng
2,025
null
null
2,025
3
26
[INTRODUCTION] This study was designed to determine the effects of diets containing different-quality forages and concentrate content on milk composition and lipogenic enzyme expression in the mammary glands of dairy cows using RNA sequencing. [METHODS] Thirty Holstein cows were randomly assigned to one of three treatm...
RNA sequencing; dairy cow; forage quality; lipid metabolic; milk fat
0.783
85
Veterinary
Veterinary
2,024
40,206,230
Assessment of renal resistive index measurement in children with immunoglobulin A vasculitis.
Reumatologia
Reumatologia
63
1
10.5114/reum/197389
eng
2,025
2
null
2,025
2
11
[INTRODUCTION] Henoch-Schönlein purpura (HSP), also known as IgA vasculitis (IgAV), is the most prevalent systemic vasculitis. Renal involvement occurs in approximately one third of children with IgAV, while biopsy-proven nephritis could be diagnosed in only 6% of patients with prolonged proteinuria or nephritic syndro...
Doppler ultrasonography; IgA vasculitis; renal resistive index
0.5
30
Immunology; Immunology and Allergy; Rheumatology
Immunology and Microbiology; Medicine
2,024
40,205,575
The impact of academic anxiety on smartphone addiction among college students: the mediating role of self-regulatory fatigue and the moderating role of mindfulness.
BMC psychology
BMC Psychol
13
1
10.1186/s40359-025-02696-y
eng
2,025
4
9
2,025
4
9
[BACKGROUND] Academic anxiety is recognized as a risk factor of smartphone addiction among college students. However, the underlying mechanisms and moderating factors remain insufficiently explored. [METHOD] This study examines the impact of academic anxiety on smartphone addiction, focusing on the mediating role of se...
Academic anxiety; College students; Mindfulness; Self-regulatory fatigue; Smartphone addiction
1.03
49
Medicine; Psychology
Medicine; Psychology
2,024
40,205,551
An epidemiological model of monkeypox: model prediction and control application.
BMC infectious diseases
BMC Infect Dis
25
1
10.1186/s12879-025-10873-y
eng
2,025
4
9
2,025
4
9
[BACKGROUND] Monkeypox (Mpox) is an emerging infectious disease caused by the Mpox virus (MPX Virus). The outbreak of Mpox epidemic has caused global panic and is now a public health incident. Various approaches have been proposed in the recent literature to study and analyze the epidemiological dynamics of this infect...
Mpox transmission model; Optimal control strategy; Parameter estimation; Sensitivity analysis; United State
1.035
137
Infectious Diseases
Medicine
2,024
40,205,391
Comparative analysis of fatty acid profiles across omnivorous, flexitarians, vegetarians, and vegans: insights from the NuEva study.
Lipids in health and disease
Lipids Health Dis
24
1
10.1186/s12944-025-02517-6
eng
2,025
4
9
2,025
4
9
[BACKGROUND] Different dietary choices can influence blood fatty acid profiles, which are crucial for maintaining physiological health and reducing disease risk. In particular, the exclusion of animal foods in vegetarian diets is associated with a higher risk of undersupply of long-chain omega (n)-3 fatty acids, which ...
n-3 fatty acid; n-6 fatty acid; Fatty acid profile; Inflammation; MUFA; PUFA; Plant-based diet; SFA; TFA
1.24
105
Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,205,384
Comparison of treatment outcomes and analysis of factors interfering with efficacy in patients with lumbar spinal stenosis undergoing unilateral unichannel and bichannel endoscopic ULBD surgery.
Journal of orthopaedic surgery and research
J Orthop Surg Res
20
1
10.1186/s13018-025-05771-7
eng
2,025
4
9
2,025
4
9
[OBJECTIVE] To compare the treatment outcomes of unilateral unichannel and bichannel endoscopic Unilateral Laminotomy for Bilateral Decompression (ULBD) surgery in patients with lumbar spinal stenosis and analyze factors interfering with efficacy. [METHODS] This retrospective study included a total of 122 patients diag...
Efficacy; Interference; Lumbar spinal stenosis; Related factors
0.877
75
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
40,204,947
Rational design of alternative treatment options for radioresistant rectal cancer using patient-derived organoids.
British journal of cancer
Br J Cancer
132
10
10.1038/s41416-025-02989-4
eng
2,025
6
null
2,025
4
10
[BACKGROUND] Resistance to radiation therapy is a common challenge in the field of oncology. Cancer cells with an increased ability to effectively repair DNA or cells with higher levels of antioxidants are more resistant to radiation. As cancer cells rely on these traits for survival, they may offer vulnerabilities tha...
null
3.144
281
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,204,585
T1 Mapping-Derived Parameters in Breast Lesions: Diagnostic Accuracy and Correlation with Pathologic Features.
Academic radiology
Acad Radiol
32
7
10.1016/j.acra.2025.03.029
eng
2,025
7
null
2,025
4
9
[RATIONALE AND OBJECTIVES] To evaluate the diagnostic potential of T1 mapping-derived parameters for distinguishing between benign and malignant breast tumors and their associations with pathologic prognostic indicators in invasive breast cancer. [MATERIALS AND METHODS] Patients who underwent breast surgery and quantit...
Breast cancer; Extracellular volume fraction; Magnetic resonance imaging; T1 mapping
0.992
113
Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,204,511
Causal associations between environmental factors and risk of IgA nephropathy and membranous nephropathy: a bidirectional Mendelian randomization and mediation analysis.
Renal failure
Ren Fail
47
1
10.1080/0886022X.2025.2486620
eng
2,025
12
null
2,025
4
9
[AIMS] IgA nephropathy (IgAN) and membranous nephropathy (MN) have intricate etiologies that are poorly understood. This study aimed to investigate the impact of genetically predicted environmental factors on IgAN and MN. [METHODS] We used bidirectional two-step Mendelian randomization (MR) analysis utilizing large-sca...
Environmental exposures; IgA nephropathy; mediation analysis; membranous nephropathy; mendelian randomization; risk factors
0.84
69
Nephrology; Critical Care and Intensive Care Medicine; Medicine
Medicine
2,024
40,204,373
Nursing staff attitudes toward family involvement in the care of psychiatric inpatients.
Archives of psychiatric nursing
Arch Psychiatr Nurs
55
null
10.1016/j.apnu.2025.151861
eng
2,025
4
null
2,025
3
17
[BACKGROUND] Historically, families were excluded from psychiatric inpatient care due to misconceptions about their role in illness development. However, contemporary views recognize families as essential support systems that enhance treatment outcomes. Despite this, practical implementation of family involvement remai...
Family involvement; Psychiatric inpatient care; Psychiatric nursing staff attitudes
0.817
68
Psychiatry and Mental Health
Medicine
2,024
40,204,264
The reno-protective effect of Empagliflozin against carbon tetrachloride (CCl4)-induced nephrotoxicity in mice halting JNK/MKK4/NRF2/NF-KB pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Food Chem Toxicol
201
null
10.1016/j.fct.2025.115439
eng
2,025
7
null
2,025
4
7
[AIM] This study designed to evaluate the reno-protective effects of Empagliflozin (EMPA), a sodium-glucose co-transporter 2 (SGLT2) inhibitor, against carbon tetrachloride (CCl4)-induced nephrotoxicity in mice targeting JNK/MKK4/NRF2/NF-KB pathway. [METHODS] Male albino mice were given EMPA (10 mg/kg, orally) for 4 we...
Acute kidney injury; Carbon tetrachloride; Empagliflozin; JNK/MKK4; Nrf2
0.801
215
Food Science; Medicine; Toxicology
Agricultural and Biological Sciences; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,204,014
Estrogenic activity of E2-conjugated GLP-1 is mediated by intracellular endolysosomal acidification and estrone metabolism.
Molecular metabolism
Mol Metab
96
null
10.1016/j.molmet.2025.102136
eng
2,025
6
null
2,025
4
7
[OBJECTIVE] Recent modifications to glucagon-like peptide 1 (GLP-1), known for its insulinotropic and satiety-inducing effects, have focused on conjugating small molecules to enable selective delivery into GLP-1R+ tissues to achieve targeted synergy and improved metabolic outcomes. Despite continued advancements in GLP...
Bioluminescence resonance energy transfer (BRET); Estradiol; Glucagon-like peptide 1; Metabolomics; Peptide conjugation; Pharmacology
3.235
115
Cell Biology; Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,024
40,203,628
Laparoscopic repair for Spigelian-inguinal hernia complex: A case report and review of literature.
International journal of surgery case reports
Int J Surg Case Rep
130
null
10.1016/j.ijscr.2025.111210
eng
2,025
5
null
2,025
3
28
[INTRODUCTION AND IMPORTANCE] Spigelian hernia, a rare primary abdominal wall defect accounting for 2 % of all hernias, poses diagnostic challenges due to its anatomical proximity to the semilunar line. Its coexistence with inguinal hernia further complicates management. This report introduces an innovative laparoscopi...
Inguinal hernia; Laparoscopic repair; Modified TAPE; Spigelian hernia
0.238
31
Surgery
Medicine
2,024
40,203,624
Bilateral mandibular osteomyelitis following chemo-radiotherapy: Critical rare case report and review of literature.
International journal of surgery case reports
Int J Surg Case Rep
130
null
10.1016/j.ijscr.2025.111277
eng
2,025
5
null
2,025
4
7
[INTRODUCTION AND IMPORTANCE] Osteomyelitis, an inflammatory condition of the bone, poses significant challenges in clinical management due to its multifactorial etiology and variable presentation. Understanding the underlying mechanisms, risk factors, and biological processes is essential for improving treatment outco...
Chemoradiotherapy; Jaw infection; Mandible; Osteomyelitis; Osteonecrosis
0.238
31
Surgery
Medicine
2,024
40,203,536
Research on sleep disorders in children with episodic idiopathic vertigo provides evidence supporting the connection to migraine.
International journal of pediatric otorhinolaryngology
Int J Pediatr Otorhinolaryngol
193
null
10.1016/j.ijporl.2025.112331
eng
2,025
6
null
2,025
4
2
[OBJECTIVES] Migraine is the most common etiology of episodic vertigo in pediatric populations. The characteristics of migraine headaches in children differ from those in adults, with initial manifestations frequently presenting as periodic syndromes. Sleep disorders are prevalent among individuals with migraines. Head...
Episodic idiopathic vertigo; Headache; Migraine; Sleep disorders
0.52
96
Otorhinolaryngology; Pediatrics, Perinatology and Child Health; Medicine
Medicine
2,024
40,203,002
The Prevalence of Undiagnosed Concussions and Their Associations With Current Symptom Reporting in Collegiate-Aged Athletes.
The Journal of head trauma rehabilitation
J Head Trauma Rehabil
null
null
10.1097/HTR.0000000000001058
eng
2,025
4
7
2,025
4
7
[OBJECTIVE] Determine the prevalence of undiagnosed concussions across the lifespan and their association with demographic and injury-related factors, prolonged recovery, and risk for subsequent injury. Test the hypothesis that prior diagnosed and undiagnosed concussions are associated with worse current-day concussion...
concussion; diagnosed; mild traumatic brain injury; sport; symptoms; undiagnosed
0.944
119
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Neurology
Health Professions; Medicine
2,024
40,202,981
Insomnia and risk of all-cause dementia: A systematic review and meta-analysis.
PloS one
PLoS One
20
4
10.1371/journal.pone.0318814
eng
2,025
null
null
2,025
4
9
[BACKGROUND] The evidence on the relationship between insomnia and risk of dementia, Alzheimer's disease (AD), and Vascular dementia (VD) is not consistent. We conducted this meta-analysis to examine the evidence for the risk of developing dementia, AD, or VD in patients with all subtypes of insomnia. [METHODS] A compr...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
40,202,590
Is surgeon assessed bone quality during total knee arthroplasty a valid tool to diagnose osteoporosis?
Archives of osteoporosis
Arch Osteoporos
20
1
10.1007/s11657-025-01531-6
eng
2,025
4
9
2,025
4
9
[UNLABELLED] Osteoporosis continues to have a high prevalence amongst people undergoing total knee arthroplasty (TKA). The surgeon assessed intraoperative bone quality using a visual analogue scale has a strong correlation with bone mineral density. Surgeon assessment of bone quality has a high specificity(100%) and po...
Bone mineral density; Bone quality; Osteoporosis; Surgeon assessed; Total knee arthroplasty
0.938
49
Orthopedics and Sports Medicine
Medicine
2,024
40,202,550
Mitigation of Injury from Myocardial Infarction by Pentamidine, an Inhibitor of the Acetyltransferase Tip60.
Cardiovascular drugs and therapy
Cardiovasc Drugs Ther
null
null
10.1007/s10557-025-07696-z
eng
2,025
4
9
2,025
4
9
[PURPOSE] There is an urgent unmet need for new pharmacologic approaches that promote re-muscularization and repair following myocardial infarction (MI). We previously reported that genetic depletion of the acetyltransferase Tip60 after MI in a mouse model activates the CM cell-cycle, reduces scarring, and restores car...
Cardiomyocyte dedifferentiation; Cell-Cycle activation; Myocardial infarction; Pentamidine; Regeneration; Tip60
1.002
83
Cardiology and Cardiovascular Medicine; Medicine; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,202,323
The Effect of Immunocorrection on Reparative Osteogenesis in Mandibular Fracture: A Histomorphometric Study.
The Journal of craniofacial surgery
J Craniofac Surg
36
5
10.1097/SCS.0000000000011404
eng
2,025
4
9
2,025
4
9
[BACKGROUND] Fracture consolidation is a fundamental factor in understanding the biological process of bone healing in human. The objective of this study was to evaluate the effects of immunocorrection after trauma surgery on bone healing process in mandibular fracture in rabbits. [METHODS] This study carried out using...
Bone healing; immunocorrection; immunomodulator; mandibular fracture; osteogenesis
0.437
90
Otorhinolaryngology; Surgery; Medicine
Medicine
2,024
40,201,759
Predicting Pregnancy in Preconception Weight Loss Trials: Is it Possible?
Obesity science practice
Obes Sci Pract
11
2
10.1002/osp4.70060
eng
2,025
4
null
2,025
4
7
[INTRODUCTION] Predicting pregnancy is a challenge in preconception weight loss intervention trials. The current study examined whether self-reported pregnancy likelihood and timing were predictive of conception. [METHODS] Adults (n = 184; 58% Hispanic; age = 33.4 ± 5.1; BMI = 33.6 ± 6.6) with overweight or obesity, pr...
gestational diabetes; measurement/assessment; pregnancy likelihood
null
null
null
null
null
40,201,706
Monkeypox: Prevention Strategies and Challenges: Updated Review.
Health science reports
Health Sci Rep
8
4
10.1002/hsr2.70640
eng
2,025
4
null
2,025
4
8
[BACKGROUND AND AIMS] The mpox virus, sometimes known as MPXV, is the cause of the disease mpox. The Monkeypox virus is a different Poxviridae family member from the orthopoxvirus (OPXV) group. Clades I and II are the two varieties of the Monkeypox virus. The mpox can spread from person to person through direct contact...
Mpox vaccine; Mpox virus; antiviral agents; clinical management; epidemics; monkeypox virus
0.567
26
Medicine
Medicine
2,024
40,201,652
Ask the experts: Community Engagement studios to inform research on cannabis use in cancer symptom management.
Journal of clinical and translational science
J Clin Transl Sci
9
1
10.1017/cts.2025.10
eng
2,025
null
null
2,025
1
30
[AIM] Despite one-third of patients with cancer using cannabis for symptom management, little is known about their access to and usage of cannabis. Community Engagement (CE) studios involving community experts with chronic health conditions were used to inform a qualitative study on access to and use of cannabis produc...
Community engagement; cancer; cannabis; community experts; health disparities
0.857
19
Medicine
Medicine
2,024
40,201,363
Pandemic-driven shift: increase in silver diamine fluoride utilization among Medicaid-enrolled children during the COVID-19 public health emergency.
Frontiers in public health
Front Public Health
13
null
10.3389/fpubh.2025.1546365
eng
2,025
null
null
2,025
3
25
[INTRODUCTION] Untreated dental caries remains a significant public health issue, particularly among children and adolescents from low-income families, where disparities persist. The COVID-19 public health emergency (PHE) changed dental care practices, leading to an increased focus on minimally aerosolizing treatments ...
health services accessibility; healthcare disparities; pediatric dentistry; reimbursement policy in health care; silver diamine fluoride
1.027
119
Public Health, Environmental and Occupational Health
Medicine
2,024
40,201,344
Single-cell sequencing and spatial transcriptomics reveal the evolution of glucose metabolism in hepatocellular carcinoma and identify G6PD as a potential therapeutic target.
Frontiers in oncology
Front Oncol
15
null
10.3389/fonc.2025.1553722
eng
2,025
null
null
2,025
3
25
[BACKGROUND] Glucose metabolism reprogramming provides significant insights into the development and progression of malignant tumors. This study aims to explore the temporal-spatial evolution of the glucose metabolism in HCC using single-cell sequencing and spatial transcriptomics (ST), and validates G6PD as a potentia...
bioinformatics; carbohydrate metabolism; hepatocellular carcinoma; metabolic reprogramming; prognostic biomarker
1.075
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,201,222
ALBI Grade Enables Risk Stratification for Bleeding Events and Refines Prognostic Prediction in Advanced HCC Following Atezolizumab and Bevacizumab.
Journal of hepatocellular carcinoma
J Hepatocell Carcinoma
12
null
10.2147/JHC.S462701
eng
2,025
null
null
2,025
4
4
[BACKGROUND AND AIMS] Atezolizumab and bevacizumab (A+B) are recommended for treating unresectable hepatocellular carcinoma (HCC). Although highly effective, A+B can lead to potentially life-threatening adverse events including bleeding. We investigated whether albumin-bilirubin (ALBI) grade identifies patients with a ...
ALBI; bleeding risk; hepatocellular carcinoma; systemic treatment
0.734
10
Hepatology; Oncology
Medicine
2,024
40,200,913
Anosmia and Upper Limb Rigidity-A Potential Phenotype of Idiopathic Normal Pressure Hydrocephalus with Cerebrospinal Fluid α-Synuclein Seeds.
Movement disorders : official journal of the Movement Disorder Society
Mov Disord
40
6
10.1002/mds.30184
eng
2,025
6
null
2,025
4
9
[BACKGROUND] The pathophysiology of idiopathic normal pressure hydrocephalus (iNPH) and its association with neurodegenerative disorders is poorly understood. [OBJECTIVES] The aim was to determine the prevalence of α-synuclein pathology in iNPH and its associations with clinical characteristics. [METHODS] We used α-syn...
SAA; anosmia; normal pressure hydrocephalus; seed amplification assay
2.988
238
Neurology; Neurology
Medicine; Neuroscience
2,024
40,200,334
Preclinical and clinical sex differences in the effects of alcohol on measures of brain dopamine: a systematic review.
Biology of sex differences
Biol Sex Differ
16
1
10.1186/s13293-025-00706-7
eng
2,025
4
8
2,025
4
8
[INTRODUCTION] Dopamine is involved in reward processing and plays a critical role in the development and progression of alcohol use disorder (AUD). However, little is known about the effect of sex on the relationship between dopamine and alcohol use/AUD. There is a critical need to identify the neurobiological mechani...
Alcohol; Alcohol use disorder; Dopamine; Sex differences
1.799
68
Endocrinology; Gender Studies
Biochemistry, Genetics and Molecular Biology; Social Sciences
2,024
40,200,277
Association between ambient particulate matter and respiratory health among schoolchildren in Dar es Salaam city, Tanzania: a cross-sectional study.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-22517-6
eng
2,025
4
8
2,025
4
8
[BACKGROUND] Urbanization and industrial activities have significantly contributed to the deterioration of air quality, with ambient particulate matter (PM2.5 and PM10) posing a major public health concern in most cities of developing countries. The impact of these pollutants on respiratory health, particularly that of...
Ambient particulate matter; Respiratory health; Schoolchildren
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,200,258
Predictive role of preoperative parameters in LAMP outcomes for myelopathy caused by COPLL.
BMC musculoskeletal disorders
BMC Musculoskelet Disord
26
1
10.1186/s12891-025-08577-0
eng
2,025
4
8
2,025
4
8
[OBJECTIVES] This study aims to assess the predictive value of preoperative parameters on recovery outcomes in patients with myelopathy caused by cervical ossification of the posterior longitudinal ligament (COPLL) undergoing laminoplasty (LAMP). [METHODS] A retrospective analysis was performed on myelopathy patients c...
COPLL; JOACMEQ; K-line; LAMP; Predictive role; Torg-Pavlov ratio
0.805
131
Orthopedics and Sports Medicine; Rheumatology
Medicine
2,024
40,200,214
A qualitative analysis on the implementation of a nudge intervention to reduce post-surgical opioid prescribing.
BMC health services research
BMC Health Serv Res
25
1
10.1186/s12913-025-12651-7
eng
2,025
4
8
2,025
4
8
[BACKGROUND] Reducing above-guideline opioid prescribing is one approach to reducing the availability of unused opioids. We describe contextual factors affecting the implementation and outcomes of a successful email 'nudge' aimed at reducing post-operative opioid prescribing, with the goal of informing future implement...
Behavioral interventions; CFIR; Implementation science; Nudges; Opioids; Surgeons
1.174
157
Health Policy
Medicine
2,024
40,199,611
Improved team cohesion and experience following geographical cohorting of clinician teams.
BMJ open quality
BMJ Open Qual
14
2
10.1136/bmjoq-2024-003136
eng
2,025
4
8
2,025
4
8
[BACKGROUND] Hospitalists frequently provide care to inpatients situated across numerous medical units, resulting in inefficiency, poor clinician experience and disjointed teamwork. We implemented geographical cohorting of clinician teams to improve team cohesion, efficiency and interprofessional team experience. [METH...
Communication; Hospital medicine; Teams; Teamwork
0.608
26
Health Policy; Leadership and Management; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,024
40,206,681
Artificial Intelligence Detection and Segmentation Models: A Systematic Review and Meta-Analysis of Brain Tumors in Magnetic Resonance Imaging.
Mayo Clinic proceedings. Digital health
Mayo Clin Proc Digit Health
2
1
10.1016/j.mcpdig.2024.01.002
eng
2,024
3
null
2,024
2
4
[OBJECTIVE] To thoroughly analyze factors affecting the generalization ability of deep learning algorithms on brain tumor detection and segmentation models. [PATIENTS AND METHODS] We searched PubMed, Embase, Web of Science, Cochrane Library, and IEEE from inception to July 25, 2023, and 19 studies with 12,000 patients ...
null
null
null
null
null
null
40,251,560
Chain effect of lifecourse reproductive characteristics and body fat and muscle on cardiovascular disease in women: a Mendelian randomization study.
Cardiovascular diabetology
Cardiovasc Diabetol
24
1
10.1186/s12933-025-02681-0
eng
2,025
4
18
2,025
4
18
[BACKGROUND] Delineating the causal chain effects of reproductive traits and fat- and muscle-related traits on cardiovascular disease (CVD) is essential for optimizing precision prevention and control of cardiovascular health in women. [METHODS] In this study, we applied the two-sample Mendelian randomization (MR) anal...
Body fat; Cardiovascular disease; Lifecourse reproductive characteristics; Mendelian randomization; Muscle
3.353
121
Cardiology and Cardiovascular Medicine; Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,024
40,251,547
Our results of the quadruple procedure in combined vitrectomy.
BMC ophthalmology
BMC Ophthalmol
25
1
10.1186/s12886-025-04018-7
eng
2,025
4
18
2,025
4
18
[PURPOSE] To reveal the outcomes of combined phacovitrectomy and supplementary scleral buckling (SB) surgery in patients with inferior break retinal detachment (RD) and proliferative vitreoretinopathy (PVR) ≥ Stage-C. [METHODS] In this retrospective study, 22 eyes of 22 patients who underwent surgery in Bozyaka Trainin...
Pars plana vitrectomy; Phacoemulsification; Proliferative vitreoretinopathy; Scleral buckling
0.72
67
Medicine; Ophthalmology
Medicine
2,024
40,251,460
Use of the adult social care outcomes toolkit (ASCOT) in research studies: an international scoping review.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Qual Life Res
null
null
10.1007/s11136-025-03958-3
eng
2,025
4
18
2,025
4
18
[PURPOSE] Since the launch of Adult Social Care Outcomes Toolkit (ASCOT) in 2012, there has been increasing interest in use of ASCOT measures in social care research and evaluation, internationally. This scoping review seeks to understand ASCOT use and the methodologies within which the measures have been applied. [MET...
ASCOT; Long-term care; Outcomes; Quality of life; Social care
1.436
179
Public Health, Environmental and Occupational Health
Medicine
2,024
40,250,884
Abdominal and concomitant thoracic HIPEC, named HITAC : Technique and post-operative courses.
Journal of visceral surgery
J Visc Surg
162
2
10.1016/j.jviscsurg.2025.01.002
eng
2,025
4
null
null
null
null
[INTRODUCTION] Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is the preferred treatment for selected patients with carcinomatosis. When diaphragmatic involvement occurs, partial diaphragm resection (DR) is necessary to achieve complete cytoreduction (CC-0). In cases of macr...
null
0.446
41
Surgery
Medicine
2,024
40,249,571
Machine learning developed immune-related exosome signature for prognosis and immunotherapy benefit in bladder cancer.
Discover oncology
Discov Oncol
16
1
10.1007/s12672-025-02354-0
eng
2,025
4
18
2,025
4
18
[BACKGROUND] Bladder cancer is one of the most common malignancies with high invasion and poor clinical outcome. Exosomes exert a vital role in tumor development, drug resistance, and immunotherapy response. [METHODS] Based on the datasets from TCGA, GSE13507, GSE31684, GSE32984 and GSE48276, immune-related exosome sig...
Bladder cancer; Exosome; Immunotherapy; Machine learning; Prognostic signature
0.88
47
Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
40,249,381
Differences in Tumor-Infiltrating Lymphocyte Counts in the Peritumoral Area in Patients Undergoing Hepatic Resection After Lenvatinib and Atezolizumab Plus Bevacizumab Therapy for Hepatocellular Carcinoma.
Cancer medicine
Cancer Med
14
8
10.1002/cam4.70445
eng
2,025
4
null
null
null
null
[AIM] With advances in systemic therapy, the number of patients with hepatocellular carcinoma (HCC) who can undergo hepatic resection has increased in recent years, but there are no reports evaluating the immune status in the peritumoral area. [METHODS] We enrolled 14 patients who underwent hepatic resection after lenv...
atezolizumab plus bevacizumab; conversion surgery; hepatocellular carcinoma; lenvatinib
1.201
95
Radiology, Nuclear Medicine and Imaging; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,249,011
Off-season beach handball participation lowers injury incidence among handball players-A cross-sectional survey on 641 athletes.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Knee Surg Sports Traumatol Arthrosc
33
6
10.1002/ksa.12677
eng
2,025
6
null
2,025
4
18
[PURPOSE] To assess the effect of beach handball training during the indoor handball off-season on the incidence of indoor handball injuries over three seasons. It was hypothesised that off-season beach handball training would be associated with a lower injury incidence in indoor handball season. [METHODS] An online su...
athletic injuries; beach handball; indoor handball; injury prevention; return to sport
1.95
160
Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,024
40,248,900
Evaluation of the Analytical Sensitivity of a Molecular Point-of-Care Assay as Compared to 3 Lateral Flow Assays for Group A Streptococcus.
The journal of applied laboratory medicine
J Appl Lab Med
10
4
10.1093/jalm/jfaf042
eng
2,025
7
1
null
null
null
[BACKGROUND] An accurate and timely diagnosis of pharyngitis caused by group A streptococcus (GAS) is essential for ensuring appropriate antibiotic therapy. Early detection through point-of-care (POC) testing is valuable in initiating effective treatment. This study aimed at evaluating the analytical sensitivity of the...
null
0.603
31
Analytical Chemistry; Biochemistry; Chemical Engineering; Pathology and Forensic Medicine; Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Medicine
2,024
40,248,727
Predicting survival in small cell lung cancer patients undergoing various treatments: a machine learning approach.
Translational lung cancer research
Transl Lung Cancer Res
14
3
10.21037/tlcr-24-331
eng
2,025
3
31
2,025
3
14
[BACKGROUND] Small cell lung cancer (SCLC) is highly metastatic, accounting for 1.796 million global cancer-related deaths in 2020, with no established standard care. This study aimed to assess treatment effects on SCLC patient survival across stages and develop a machine learning-based survival prediction tool for acc...
Small cell lung cancer (SCLC); machine learning; survival
1.243
70
Oncology
Medicine
2,024
40,248,520
Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh.
International journal of cardiology. Cardiovascular risk and prevention
Int J Cardiol Cardiovasc Risk Prev
25
null
10.1016/j.ijcrp.2025.200399
eng
2,025
6
null
2,025
4
4
[AIMS] Evidence on cardiovascular (CV) risk stratification in Bangladeshi patients with type 2 diabetes mellitus (T2DM) who are asymptomatic for cardiovascular disease (CVD) is limited. This study aimed to assess the 10-year CV risk in newly diagnosed patients with T2DM. [METHODS] In 2023, a cross-sectional study was c...
10-Year cardiovascular risk; QRISK3; Risk assessment; Sleep; Type 2 diabetes
null
null
null
null
null
40,248,365
Assessment of the placental microbiota of preterm infants with pneumonia: a case control study.
Frontiers in cellular and infection microbiology
Front Cell Infect Microbiol
15
null
10.3389/fcimb.2025.1511141
eng
2,025
null
null
2,025
4
3
[OBJECTIVE] To investigate the specific characteristics and differences in the placental microbiome of preterm infants with and without pneumonia. [METHODS] Fifty-nine infants born at 32-36 weeks' gestation were enrolled in this study. Among them, 33 developed pneumonia within 48 hours of birth, while the remaining 26 ...
16S rRNA; microbiota; placental; pneumonia; preterm infants
1.393
136
Immunology; Infectious Diseases; Medicine; Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,024
40,248,146
The prevalence of metabolic syndrome in patients with non-alcoholic fatty liver disease in primary care clinics at King Saud University Medical City, Riyadh, Saudi Arabia.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
16
null
10.3389/fendo.2025.1551201
eng
2,025
null
null
2,025
4
3
[BACKGROUND] Metabolic syndrome is present in a subset of individuals harboring a constellation of metabolic risk factors that heightens their likelihood of developing coronary artery disease. Non-alcoholic fatty liver disease (NAFLD) manifests through the incremental accumulation of fat within liver cells in the absen...
NCEP/ATP-III; Saudi Arabia; hyperglycemia; metabolic syndrome; non-alcoholic fatty liver disease
1.472
138
Endocrinology, Diabetes and Metabolism
Medicine
2,024
40,248,055
Amoxicillin high-dose dual therapy for Helicobacter pylori primary eradication: Proton pump inhibitor and potassium-competitive acid blocker, which's better?
World journal of gastroenterology
World J Gastroenterol
31
13
10.3748/wjg.v31.i13.100863
eng
2,025
4
7
null
null
null
[BACKGROUND] Effective acid suppression significantly enhances the eradication rate of Helicobacter pylori (H. pylori). [AIM] To assess the efficacy and safety of high-dose dual therapy (HDDT) utilizing various highly potent antisecretory medications, thereby providing additional clinical guidance for H. pylori eradica...
Eradication rate; Esomeprazole; Helicobacter pylori; High-dose dual therapy; Vonoprazan
null
null
null
null
null
40,248,019
Validity and reliability of healthy food knowledge and healthy food preferences scale for preschool children.
Frontiers in pediatrics
Front Pediatr
13
null
10.3389/fped.2025.1507055
eng
2,025
null
null
2,025
4
3
[INTRODUCTION] Early childhood nutrition plays a critical role in shaping lifelong health outcomes, yet preschool children in low- and middle-income countries often have poor dietary habits and limited knowledge of healthy foods. This study aimed to validate and assess the reliability of the 9-item Healthy Food Knowled...
healthy food knowledge (HFK_PS); healthy food preference (HFP_PS); preschool children; reliability; validity
0.738
83
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,247,920
Mediation of executive functions in the relationship between motor skills and psychosocial health in preschool children.
Journal of exercise science and fitness
J Exerc Sci Fit
23
3
10.1016/j.jesf.2025.04.002
eng
2,025
7
null
2,025
4
3
[PURPOSE] Early motor skills develop alongside executive functions and psychosocial health. However, the interaction between these elements in early childhood is not well-studied. This study aimed to examine whether executive functions mediate the relationship between motor skills and psychosocial health. [METHODS] A t...
null
0.991
35
Pharmaceutical Science; Pharmacology; Physical Therapy, Sports Therapy and Rehabilitation; Public Health, Environmental and Occupational Health; Sports Science
Health Professions; Medicine; Nursing; Pharmacology, Toxicology and Pharmaceutics
2,024
40,247,729
The effect of flavonoid and subclasses supplementation on prostate specific antigen, hormonal parameters and prostate cancer risk: a systematic review and meta-analysis of randomized controlled trials.
Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
Arch Ital Urol Androl
97
2
10.4081/aiua.2025.13645
eng
2,025
6
30
2,025
4
17
[INTRODUCTION AND OBJECTIVES] Prostate cancer (PCa) is a significant concern and burden worldwide. Several studies suggest that flavonoids have a significant potential as an anti-cancer agent, but the evidence remains controversial. This study aims to assess the effect of flavonoids and its subclasses supplementation o...
null
null
null
null
null
null
40,247,691
Disclosing racial trauma in psychological therapy: Exploring the experiences of racially minoritised people in the UK.
Psychology and psychotherapy
Psychol Psychother
null
null
10.1111/papt.12592
eng
2,025
4
18
2,025
4
18
[OBJECTIVES] Exposure to racism is repeatedly experienced by individuals from racially minoritised backgrounds, and has a range of negative emotional, physical and social consequences; however, its traumatising effects are under-recognised. Further, psychological therapists often lack sufficient knowledge, training and...
antiracism; clinical practice; equality, diversity and inclusion (EDI); psychological therapy; racially minoritised; racism; therapeutic relationship
1.341
78
Arts and Humanities; Clinical Psychology; Developmental and Educational Psychology; Medicine; Psychiatry and Mental Health
Arts and Humanities; Medicine; Psychology
2,024
40,247,421
Mediating role of pain sensitization in preoperative and postoperative pain in knee osteoarthritis patients.
European journal of medical research
Eur J Med Res
30
1
10.1186/s40001-025-02485-8
eng
2,025
4
17
2,025
4
17
[OBJECTIVE] This study aims to explore the relationship between preoperative and postoperative pain in patients with knee osteoarthritis (KOA) undergoing total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKR), and to assess the mediating roles of central and peripheral sensitization. [METHODS] This ...
Knee arthroplasty; Mediating effect; Pain management; Pain sensitization; Postoperative pain; Preoperative pain
null
70
Medicine
Medicine
2,024
40,247,404
Stem design affects templating adherence in total hip arthroplasty - a retrospective cohort study comparing two types of cementless short stems.
Journal of orthopaedic surgery and research
J Orthop Surg Res
20
1
10.1186/s13018-025-05801-4
eng
2,025
4
17
2,025
4
17
[BACKGROUND] Preoperative templating is crucial when performing total hip arthroplasty (THA) as it facilitates the correct restoration of the joint biomechanics and reduces the risk of adverse events associated with component under- or over-sizing. Templating and execution of stem placement is highly dependent on the a...
Cementless short stem; Direct anterior approach; Neck-resecting; Neck-sparing; Templating; Total hip arthroplasty
0.877
75
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
40,247,335
The story of pain in people with dementia: a rationale for digital measures.
BMC medicine
BMC Med
23
1
10.1186/s12916-025-04057-3
eng
2,025
4
17
2,025
4
17
[BACKGROUND] The increasingly older world population presents new aging-related challenges, especially for persons with dementia unable to express their suffering. Pain intensity and the effect of pain treatment are difficult to assess via proxy rating and both under- and overtreatment lead to neuropsychiatric symptoms...
Challenges; Dementia; Digital phenotyping; Older adults; Pain; Pain assessment; Sensing technology
2.846
199
Medicine
Medicine
2,024
40,247,164
Molecular serotyping and antimicrobial susceptibility profiles of Pasteurella multocida isolated from cases of hemorrhagic septicemia in cattle from selected districts of Keffa and Bench Sheko zones, South West Ethiopia.
BMC microbiology
BMC Microbiol
25
1
10.1186/s12866-025-03947-z
eng
2,025
4
17
2,025
4
17
[BACKGROUND] Hemorrhagic septicemia is a highly fatal disease of cattle caused by the bacteria; Pasteurella multocida serotypes B and E in Asia and Africa respectively. Even though the capsular serotype E is considered to be the common cause of Hemorrhagic septicemia in Africa, there is not enough evidence that other s...
Antimicrobial; Cattle; P. multocida; PCR; Serotype; South West Ethiopia; Hemorrhagic septicemia
1.032
147
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,024
40,247,159
Clinical and molecular characteristics of Staphylococcus aureus isolates from patients with COVID-19 in Southwest China.
BMC infectious diseases
BMC Infect Dis
25
1
10.1186/s12879-025-10868-9
eng
2,025
4
17
2,025
4
17
[BACKGROUND] This study investigated the clinical and molecular characteristics of Staphylococcus aureus (S. aureus) isolates from patients with coronavirus disease 19 (COVID- 19) at West China Hospital between December 1, 2022 and January 31, 2023. [METHODS] In total, 102 strains isolated from sputum, bronchoalveolar ...
Staphylococcus aureus; Antimicrobial susceptibility; COVID- 19; Multilocus sequence typing; Virulence gene
1.035
137
Infectious Diseases
Medicine
2,024
40,247,154
A cross-sectional study of the relationship between health literacy and health-promoting lifestyles in patients with hypertension in northwest Iran.
BMC primary care
BMC Prim Care
26
1
10.1186/s12875-025-02819-9
eng
2,025
4
17
2,025
4
17
[BACKGROUND] Health literacy is a key factor in determining the use of health-related information, promoting health, and improving the quality of life. Therefore, the present study was conducted to investigate the relationship between health literacy and health-promoting lifestyle in patients with hypertension. [METHOD...
Cardiovascular diseases; Chronic diseases; Health behaviors; Health literacy; Health-Promoting lifestyle; Hypertension; Iran; Patient; Silent killer
1.073
95
Family Practice; Medicine
Medicine
2,024
40,246,675
Controlling nutritional status score as a survival prognosticator in patients with head and neck cancer.
Journal of the Formosan Medical Association = Taiwan yi zhi
J Formos Med Assoc
null
null
10.1016/j.jfma.2025.04.017
eng
2,025
4
16
2,025
4
16
[PURPOSE] This study aimed to evaluate the prognostic significance of the preoperative Controlling Nutritional Status (CONUT) score in head and neck squamous cell carcinoma (HNSCC). [METHODS] Patients with HNSCC who underwent radical surgery between 2008 and 2017 were retrospectively analyzed and randomly divided into ...
CONUT score; Head and neck cancer; Lymphocyte count; Serum albumin; Serum total cholesterol
null
null
null
null
null
40,246,562
QbTest for ADHD assessment and medication management: a mixed-methods systematic review of impact on clinical outcomes and patient, carer and clinician experiences.
BMJ open
BMJ Open
15
4
10.1136/bmjopen-2024-095479
eng
2,025
4
17
2,025
4
17
[OBJECTIVES] To explore patient, carer and clinician experiences of the QbTest and its impact on patient outcomes for attention deficit hyperactivity disorder (ADHD) diagnosis and medication management. [DESIGN] Mixed-methods systematic review. [DATA SOURCES] MEDLINE, EMBASE, PsycINFO, CINAHL, ClinicalTrials.gov and WH...
Attention Deficit Disorder with Hyperactivity; Child adolescent psychiatry; Health Services; PSYCHIATRY; QUALITATIVE RESEARCH; Review
1.016
176
Medicine
Medicine
2,024
40,246,295
Consumer-Grade Neurofeedback With Mindfulness Meditation: Meta-Analysis.
Journal of medical Internet research
J Med Internet Res
27
null
10.2196/68204
eng
2,025
4
17
2,025
4
17
[BACKGROUND] There is burgeoning interest in the application of neuroscientific technology to facilitate meditation and lead to beneficial psychological outcomes. One popular approach is using consumer-grade neurofeedback devices to deliver feedback on brain targets during meditation (mindfulness-based neurofeedback). ...
Muse; cognition; consumer grade; device; meditation; meta-analyses; mindfulness; neurofeedback; neuroscientific technology; neurotechnologies; neurotechnology; randomized; stress
1.992
214
Health Informatics
Medicine
2,024
40,246,232
Computed Tomography Cardiac Angiography Findings in Patients With Sheehan Syndrome.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Endocr Pract
31
7
10.1016/j.eprac.2025.04.006
eng
2,025
7
null
2,025
4
15
[OBJECTIVE] Sheehan Syndrome (SS), or postpartum pituitary necrosis, is associated with an elevated risk of atherosclerotic cardiovascular (CV) diseases, driven by factors such as dyslipidemia, chronic inflammation, and growth hormone deficiency. To better understand the prevalence and characteristics of atheroscleroti...
CT angiography; coronary artery disease; coronary calcification; sheehan syndrome
1.182
107
Endocrinology, Diabetes and Metabolism; Medicine; Endocrinology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,246,076
S-Adenosylmethionine Inhibits Plasminogen-Activating Inhibitor-1 and Protects Male Mice From FOLFOX-Induced Liver Injury.
Cellular and molecular gastroenterology and hepatology
Cell Mol Gastroenterol Hepatol
19
8
10.1016/j.jcmgh.2025.101513
eng
2,025
null
null
2,025
4
17
[BACKGROUND AND AIMS] FOLFOX, often used in patients with colorectal liver metastases, can cause sinusoidal obstruction syndrome (SOS) hindering subsequent treatment. S-adenosylmethionine (SAMe) is hepatoprotective and here we investigated whether it protects against FOLFOX-induced hepatotoxicity and defined the underl...
Colorectal Liver Metastasis; Sinusoidal Obstruction Syndrome
3.069
75
Gastroenterology; Hepatology
Medicine
2,024
40,245,874
Functional Mobility and Its Relationship With Cognition in Older Adults With Normal Cognition, Motoric Cognitive Risk Syndrome, and Mild Alzheimer's Disease.
Journal of geriatric physical therapy (2001)
J Geriatr Phys Ther
48
2
10.1519/JPT.0000000000000455
eng
null
null
null
2,025
4
9
[BACKGROUND AND PURPOSE] Motoric cognitive risk syndrome (MCR) is a predementia syndrome and is a strong predictor of Alzheimer's disease (AD). Functional mobility, such as balance, sit-stand transitions, and turning, has not been clearly investigated in this population. This study aimed to compare functional mobility ...
Alzheimer dementia; balance; cognitive function; gait; motor-cognitive interactions
null
null
null
null
null
40,245,523
Nitric oxide biomarkers and circulatory failure in critical illness: A cohort study.
Journal of critical care
J Crit Care
88
null
10.1016/j.jcrc.2025.155083
eng
2,025
8
null
2,025
4
16
[PURPOSE] Arterial hypotension is frequently observed in critically ill patients. Nitric oxide (NO) is pivotal in vasodilation. We investigated the associations between NO-biomarkers (asymmetrical dimethylarginine (ADMA), symmetric dimethylarginine (SDMA), arginine, and homoarginine) and treatment with norepinephrine a...
Arginine; Asymmetric dimethylarginine; Circulation; Homoarginine; Intensive care; Nitric oxide; Symmetric dimethylarginine
1.021
109
Critical Care and Intensive Care Medicine
Medicine
2,024
40,245,469
Upfront and interval debulking surgery in advanced/metastatic endometrial cancer in the era of molecular classification.
European journal of obstetrics, gynecology, and reproductive biology
Eur J Obstet Gynecol Reprod Biol
310
null
10.1016/j.ejogrb.2025.113958
eng
2,025
6
null
2,025
4
12
[OBJECTIVE] To evaluate oncologic outcomes and prognostic factors of the different molecular subtypes of advanced/metastatic endometrial cancer treated with primary debulking surgery (PDS) or neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS). [METHODS] We conducted a retrospective analysis of...
Endometrial cancer; Molecular classification; Neoadjuvant chemotherapy; Primary cytoreductive surgery
null
null
null
null
null
40,245,261
Cannabinoid Receptors Reduced Early Brain Damage by Regulating NOX-2 and the NLRP3 Inflammasome in an Animal Model of Intracerebral Hemorrhage.
CNS neuroscience therapeutics
CNS Neurosci Ther
31
4
10.1111/cns.70385
eng
2,025
4
null
null
null
null
[BACKGROUND] Intracerebral hemorrhage (ICH) is a leading cause of death and disability worldwide. Following the initial mechanical injury caused by hematoma expansion, a secondary injury occurs, characterized by the production of reactive oxygen species (ROS) generated by NOX-2 and neuroinflammation, which is exacerbat...
CB1 receptor; cannabinoids; intracerebral hemorrhage; neuroinflammation; oxidative stress
null
null
null
null
null
40,245,046
The red blood cell distribution width is associated with all-cause and cardiovascular mortality among individuals with non-alcoholic fatty liver disease.
PloS one
PLoS One
20
4
10.1371/journal.pone.0321789
eng
2,025
null
null
2,025
4
17
[BACKGROUND] Identifying reliable prognostic indicators is essential for the appropriate management of non-alcoholic fatty liver disease (NAFLD). Red blood cell distribution width (RDW) has been established as an inflammatory marker associated with cardiovascular outcomes. This study aimed to evaluate the association b...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
40,244,514
Risk Factors for Lymph Node Metastasis in Stage pT1 Invasive Lung Adenocarcinoma.
Current medical science
Curr Med Sci
45
3
10.1007/s11596-025-00016-4
eng
2,025
6
null
2,025
4
17
[OBJECTIVE] To analyze the risk factors for lymph node metastasis (LNM) in patients with stage pT1 lung adenocarcinoma to select a more appropriate surgical option. [METHODS] In this retrospective study, 294 patients with postoperative pathologically confirmed stage pT1 invasive lung adenocarcinoma were collected and d...
Epidermal growth factor receptor; Ground-glass nodules; Lung adenocarcinoma; Lung segmentectomy; Lymph node metastasis
0.582
42
Biochemistry; Genetics
Biochemistry, Genetics and Molecular Biology
2,024
40,244,464
Metal-on-metal arthroplasty, cobalt toxicity, and development of cognitive impairment: a systematic review.
Archives of orthopaedic and trauma surgery
Arch Orthop Trauma Surg
145
1
10.1007/s00402-025-05869-x
eng
2,025
4
17
2,025
4
17
[BACKGROUND] Neurological dysfunction secondary to cobalt toxicity has been described as a potential complication of metal on metal (MoM) arthroplasty, however, to date the full extent of this association remains unclear. Currently, no national guideline on the management or follow-up of MoM arthroplasty patients recom...
Arthroplasty; Cobalt toxicity; Cognitive; Dementia; Metal
1.05
98
Medicine; Orthopedics and Sports Medicine; Surgery
Medicine
2,024
40,244,462
Alveolar macrophages polarization switch via α2-adrenoceptor activation ameliorates pulmonary inflammation following kidney ischemia reperfusion.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Inflamm Res
74
1
10.1007/s00011-025-02029-0
eng
2,025
4
17
2,025
4
17
[PURPOSE] The present study aimed to explore the anti-inflammatory mechanism of dexmedetomidine (Dex), an α2-adrenoceptor (α2-AR) agonist, in renal ischemia-reperfusion (RIR)-induced acute lung injury (ALI). [METHODS] RIR was induced in C57BL/6J mice by bilateral renal pedicles occlusion for 60 min followed by 24 h of ...
Acute lung injury; Dexmedetomidine; Macrophage polarization; Renal ischemia-reperfusion
1.388
112
Immunology; Pharmacology
Immunology and Microbiology; Pharmacology, Toxicology and Pharmaceutics
2,024
40,244,442
Participation in life activities after hematopoietic cell transplantation in older adults.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
33
5
10.1007/s00520-025-09399-5
eng
2,025
4
17
2,025
4
17
[OBJECTIVES] This study aims to measure activity participation and describe barriers and goals for participation in older adults post-HCT. [MATERIALS AND METHODS] In a convergent mixed methods design, we quantitatively assessed four domains of participation (instrumental, low demand leisure, high demand leisure, and so...
Hematopoietic cell transplant; Lived experience; Physical activity; Quality of life; Survivorship
1.109
143
Oncology; Rehabilitation; Oncology
Medicine; Nursing
2,024
40,244,421
Acute intraocular pressure responses changes during dynamic resistance training in primary open-angle glaucoma patients and age-matched controls.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Graefes Arch Clin Exp Ophthalmol
null
null
10.1007/s00417-025-06814-9
eng
2,025
4
17
2,025
4
17
[BACKGROUND] Physical exercise has been proposed as a feasible strategy for preventing and managing glaucoma by modulating intraocular pressure (IOP) and ocular perfusion pressure (OPP). The primary objective of this cross-sectional study was to assess the IOP and OPP responses to dynamic resistance exercises (leg exte...
Biceps curl; Glaucoma management; Leg extension; Ocular health; Physical activity
null
null
null
null
null
40,244,360
FTO rs9939609 polymorphism is associated with dietary quality in Korean females.
European journal of nutrition
Eur J Nutr
64
4
10.1007/s00394-025-03670-5
eng
2,025
4
17
2,025
4
17
[PURPOSE] Variation in fat mass and obesity-associated gene (FTO) is a critical risk factor in the etiology of obesity. FTO is associated with preference and sensory perception of nutrients and dietary intake. However, the effect of genetic variation on overall dietary quality has not yet been fully elucidated. This st...
FTO; Dietary quality; Nutrient intake; Obesity; Single nucleotide polymorphism
1.346
125
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
40,243,343
Cost-Effectiveness of Hospital-at-Home and Fecal Microbiota Transplantation in Treating Older Patients With Clostridioides difficile.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clin Infect Dis
null
null
10.1093/cid/ciaf104
eng
2,025
4
17
2,025
4
17
[BACKGROUND] Clostridioides difficile infection (CDI) primarily affects older patients with comorbid conditions and has a high mortality rate. Fecal microbiota transplantation (FMT) is effective and cost-effective for CDI. In a recent study, we demonstrated the clinical benefits of combining hospital-at-home care with ...
Clostridioides difficile; cost-Effectiveness analysis; fecal microbiota transplantation; geriatrics; home-care services
2.992
398
Infectious Diseases; Microbiology
Medicine
2,024
40,243,325
Effects of Loteprednol Etabonate and Ketorolac Tromethamine on Intraocular Inflammation and Oxidative Stress After Paracentesis-Induced Blood-Aqueous Barrier Breakdown in Cats.
Veterinary ophthalmology
Vet Ophthalmol
null
null
10.1111/vop.70020
eng
2,025
4
17
2,025
4
17
[OBJECTIVE] To compare the effects of loteprednol etobonate (LE) and ketorolac tromethamine (KT) on pupil diameter (PD) and aqueous humor levels of prostaglandin E2 (PGE2), total protein (TP), and glutathione (GSH) following paracentesis-induced intraocular inflammation in cats. [METHODS] Thirty cats (n = 10/group) und...
NSADs; corticosteroids; glutathione; prostaglandin E2; topical; uveitis
0.568
64
Veterinary
Veterinary
2,024
40,243,205
Diverging cognitive benefits from education between rural and urban middle-aged and older adults in the USA.
BJPsych open
BJPsych Open
11
3
10.1192/bjo.2025.45
eng
2,025
4
17
2,025
4
17
[BACKGROUND] Subjective cognitive decline (SCD) is defined as self-reported increase in confusion or memory loss. There is limited research on the interplay between rural-urban residence and education on SCD. [AIMS] Examine rural-urban differences in SCD, and whether education moderates this relationship. [METHOD] Resp...
Cognitive decline; education; older adult; rural; urban
1.302
50
Psychiatry and Mental Health
Medicine
2,024
40,243,049
Comparison of clinical outcomes of phacoemulsification with implantation of two new aspheric intraocular lenses: Real-world data.
Indian journal of ophthalmology
Indian J Ophthalmol
73
Suppl 3
10.4103/IJO.IJO_2395_24
eng
2,025
6
1
2,025
4
17
[PURPOSE] This study aims to compare the visual and refractive outcomes of two new aspheric intraocular lenses (IOLs), that is, Clareon (Model CNA0T0) and Tecnis Eyhance (Model ICB00), in patients undergoing phacoemulsification cataract surgery. [METHODS] A retrospective comparative analysis was conducted at a tertiary...
Aspheric intraocular lens; Clareon; Eyhance
0.631
79
Ophthalmology
Medicine
2,024
40,242,922
Stimulus-preceding negativity and P3 reflecting relative amounts of attention allocation between primary and secondary tasks.
Neuroreport
Neuroreport
36
8
10.1097/WNR.0000000000002165
eng
2,025
5
14
2,025
4
11
[OBJECTIVE] This study examined event-related potentials, particularly P3, in two attention states: a 'focused attention state', wherein attention was fully allocated to a primary task, and a 'poor attention state', wherein attention was disrupted by a secondary task, to elucidate attention allocation mechanisms during...
attention allocation; dipole analysis; multitasking; slow potential
null
null
null
null
null
40,242,906
Macrophage requirements for abatacept response in rheumatoid arthritis.
Clinical and experimental rheumatology
Clin Exp Rheumatol
43
5
10.55563/clinexprheumatol/s42d3g
eng
2,025
5
null
2,025
4
9
[OBJECTIVES] Abatacept (ABA) is used for its ability to dampen T cell co-stimulation and because it could act on antigen-presenting cells in an indoleamine 2,3-dioxygenase (IDO)-dependent manner. The objective of this study was to identify biomarkers of ABA response in rheumatoid arthritis (RA) patients and to determin...
null
1.004
112
Immunology; Immunology and Allergy; Rheumatology
Immunology and Microbiology; Medicine
2,024
40,242,405
Breath-Actuated Nebulizers for Asthma and Chronic Obstructive Pulmonary Disease Exacerbation: A Monte Carlo Simulation Demonstrating National Cost Savings and Length of Stay Reduction.
Journal of the American College of Emergency Physicians open
J Am Coll Emerg Physicians Open
6
3
10.1016/j.acepjo.2025.100112
eng
2,025
6
null
2,025
4
4
[OBJECTIVES] Breath-actuated nebulizers (BANs) deliver medication only during inspiration, and prior studies have demonstrated their increased efficacy for asthma and chronic obstructive pulmonary disease (COPD) exacerbations compared to continuous nebulizers. However, the widespread adoption of BAN has been limited by...
COPD exacerbation; Monte Carlo simulation; asthma exacerbation; breath-actuated; cost savings; length of stay reduction; nebulizer
null
null
null
null
null
40,242,369
Novel Risk Factors for Uveal Melanoma in Adolescent and Young Adult Patients: A Comprehensive Case-Control Analysis.
Ophthalmology science
Ophthalmol Sci
5
4
10.1016/j.xops.2024.100687
eng
2,025
null
null
2,024
12
24
[PURPOSE] To identify risk factors associated with uveal melanoma (UM) in adolescents and young adults (AYAs). [DESIGN] A retrospective case-control study. [PARTICIPANTS] Two hundred forty-seven UM patients aged 13 to 45 treated with proton beam radiation therapy and 401 age- and sex-matched controls at a tertiary acad...
Adolescents and young adults; Ocular melanoma; Proton beam radiation therapy; Risk factors; Uveal melanoma
1.91
20
Ophthalmology
Medicine
2,024
40,242,261
Pretreatment HIV-1 Drug Resistance Among Newly Diagnosed People in Eastern Ethiopia.
Health science reports
Health Sci Rep
8
4
10.1002/hsr2.70672
eng
2,025
4
null
2,025
4
16
[BACKGROUND AND AIMS] In Ethiopia, HIV-1 pretreatment drug resistance (PDR) data are limited owing to a lack of routine genotyping resistance tests. This study aimed to determine the prevalence of HIV-1 PDR mutations and genetic diversity among newly diagnosed people with HIV in eastern Ethiopia. [METHODS] HIV RNA was ...
Ethiopia; pretreatment drug resistance
0.567
26
Medicine
Medicine
2,024
40,242,146
Early childhood lower-airway symptoms and airway hyperresponsiveness linked to school-age small-airway dysfunction.
The journal of allergy and clinical immunology. Global
J Allergy Clin Immunol Glob
4
2
10.1016/j.jacig.2025.100454
eng
2,025
5
null
2,025
3
18
[BACKGROUND] The role of early airway hyperresponsiveness (AHR) in the subsequent small-airway lung function remains unclear. [OBJECTIVE] We assessed via a prospective follow-up study the small-airway lung function of schoolchildren with early childhood lower-airway symptoms and AHR to methacholine and compared the fin...
Airway hyperresponsiveness; atopy; maternal smoking; parental smoking; preschool children; school-age children; skin prick test; small airways; small-airway dysfunction
null
null
null
null
null
40,242,022
Comparison of the thermal bone damage done by the oscillating saw and bone mill burr during total knee arthroplasty.
Journal of clinical orthopaedics and trauma
J Clin Orthop Trauma
65
null
10.1016/j.jcot.2025.102992
eng
2,025
6
null
2,025
3
28
[BACKGROUND] Thermal osteonecrosis from bone cutting during total knee arthroplasty (TKA) may cause aseptic implant loosening. The study compares thermal bone injury from oscillating saw (CTKA) and bone milling burr treatments (RATKA). [METHOD] A prospective study comparing thermal necrosis during CTKA and RATKA was pe...
Bone milled burr; Conventional total knee arthroplasty; Oscillating saw; Robotic-assisted total knee arthroplasty; Thermal osteonecrosis
0.672
45
Orthopedics and Sports Medicine
Medicine
2,024
40,241,902
Pregnancy outcomes of 4,200 fetuses with increased nuchal translucency in Henan, China.
Frontiers in medicine
Front Med (Lausanne)
12
null
10.3389/fmed.2025.1514504
eng
2,025
null
null
2,025
4
2
[BACKGROUND AND OBJECTIVE] Increased nuchal translucency (NT) thickness measured at 11-14 weeks of gestation in fetuses has been linked to adverse pregnancy outcomes. This study aimed to evaluate pregnancy outcomes in fetuses with NT ≥3.0 mm. [METHODS] This retrospective analysis included 4,200 singleton pregnancies di...
chromosome abnormalities; first-trimester screening; nuchal translucency thickness; pregnancy outcome; ultrasound soft indicators
0.962
102
Medicine
Medicine
2,024
40,241,584
Chitinase improves the available energy, amino acids digestibility of black soldier fly and fecal microbiota of growing pigs.
Animal bioscience
Anim Biosci
38
8
10.5713/ab.24.0920
eng
2,025
8
null
2,025
4
11
[OBJECTIVE] The main objective of this study was to determine the energy value and digestibility of amino acids in growing pigs fed black soldier fly (BSF) with chitinase supplementation and its effect on fecal microbiota. [METHODS] In Exp. 1, eighteen barrows with initial body weight (BW) of 31.6±1.2 kg were randomly ...
Amino Acids Digestibility; Black Soldier Fly; Chitinase; Energy Value; Fecal Microbiota; Growing Pigs
0.694
89
Animal Science and Zoology; Veterinary; Food Science; Physiology; Genetics
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Veterinary
2,024
40,241,427
Firearm Screening and Gun Lock Distribution in an Urban, Academic Pediatric Emergency Department.
Pediatric emergency care
Pediatr Emerg Care
41
7
10.1097/PEC.0000000000003384
eng
2,025
7
1
2,025
4
17
[OBJECTIVES] To examine firearm access and storage practices among parents/guardians of pediatric emergency department (PED) patients, and to determine whether the distribution of gun locks impacts overall storage practices. [MATERIALS AND METHODS] This was a single-center, prospective observational cohort study in an ...
firearm injuries; gun lock; pediatric emergency medicine; pediatric trauma; safe storage
0.549
79
Emergency Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,024
40,241,404
Intraocular lens power calculation accuracy after keratorefractive lenticule extraction with the novel ESCRS post keratorefractive surgery calculator.
Journal of cataract and refractive surgery
J Cataract Refract Surg
null
null
10.1097/j.jcrs.0000000000001673
eng
2,025
4
17
2,025
4
17
[PURPOSE] To compare IOL power calculation accuracy after keratorefractive lenticule extraction (KLEx) using the ESCRS online calculator versus ray tracing, the current gold standard. [SETTING] Multicenter study at Ludwig-Maximilians-University Eye Hospital (Munich, Germany) and SMILE Eyes Clinics (Germany, Austria). [...
null
1.425
169
Ophthalmology; Sensory Systems; Surgery
Medicine; Neuroscience
2,024
40,241,311
Clinical implications of squamous cell carcinoma in the colon and rectum: A comprehensive analysis from the National Cancer Database.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Colorectal Dis
27
4
10.1111/codi.70074
eng
2,025
4
null
null
null
null
[AIM] Squamous cell carcinoma (SCC) of the colon and rectum represents an exceptionally rare manifestation of gastrointestinal malignancy. The primary aim of this study was to elucidate baseline characteristics of colon SCC and its impact on overall survival (OS) in comparison with rectal SCC. [METHOD] We conducted a r...
colon cancer; oncological outcomes; overall survival; rectal cancer; squamous cell carcinoma
1.005
110
Gastroenterology
Medicine
2,024
40,241,196
Impact of nucleos(t)ide analogue therapy on the incidence of Alzheimer's disease in patients with chronic hepatitis B virus infection.
Alzheimer's research therapy
Alzheimers Res Ther
17
1
10.1186/s13195-025-01729-3
eng
2,025
4
16
2,025
4
16
[BACKGROUND] Long-term therapy with nucleos(t)ide analogs (NUCs) is inevitable for chronic hepatitis B (CHB) patients. However, how NUC therapy on the developing Alzheimer's disease (AD) in these patients remains controversial. [METHODS] This retrospective cohort study used the Korean National Health Insurance Service ...
Chronic hepatitis B virus; Incidence; Nucleos(t)ide analogs
null
null
null
null
null