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40,522,937
Understanding the combined symptom medication score in the light of contexts and mechanisms.
PloS one
PLoS One
20
6
10.1371/journal.pone.0326143
eng
2,025
null
null
2,025
6
16
[BACKGROUND] In a clinical trial of allergen-specific immunotherapy for allergic rhinoconjunctivitis, the Combined Symptom Medication Score (CSMS) was utilized as the primary endpoint. This was aligned with the European Academy of Allergy and Clinical Immunology recommendation. However, participants wanted to elaborate...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
40,522,925
Maternal thyroid function during pregnancy and early adolescent regional differences in cerebral gray matter morphology.
The Journal of clinical endocrinology and metabolism
J Clin Endocrinol Metab
null
null
10.1210/clinem/dgaf349
eng
2,025
6
16
2,025
6
16
[BACKGROUND] Thyroid hormone regulates fetal brain development. Both low and high maternal thyroid function during early pregnancy has been associated with smaller offspring total gray matter and cortex volume. However, it remains unknown whether regional gray matter differences underlie global brain morphology finding...
offspring brain development; pregnancy; repeated measurements; structural MRI; thyroid
2.183
400
Biochemistry; Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,522,669
Paternal Perinatal Depression, Anxiety, and Stress and Child Development: A Systematic Review and Meta-Analysis.
JAMA pediatrics
JAMA Pediatr
179
8
10.1001/jamapediatrics.2025.0880
eng
2,025
8
1
null
null
null
[IMPORTANCE] This systematic review and meta-analysis comprehensively synthesizes the extant literature on the association of paternal perinatal mental distress (ie, depression, anxiety, and stress) with offspring development from birth to adolescence. [OBJECTIVE] To provide a meta-analytic synthesis of the literature ...
null
5.085
231
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,522,644
Cash Transfers and Their Effect on Maternal and Young Children's Health: A Randomized Clinical Trial.
JAMA pediatrics
JAMA Pediatr
179
8
10.1001/jamapediatrics.2025.1612
eng
2,025
8
1
null
null
null
[IMPORTANCE] Mothers and children in low-income households are more likely to experience worse mental and physical health than those from higher-income households. [OBJECTIVE] To determine the effect of 4 years of monthly unconditional cash transfers on the mental health of mothers with low-income and the physical heal...
null
5.085
231
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,522,574
Validation of the Chinese version of the financial toxicity scale in patients with wet age-related macular degeneration.
Journal of patient-reported outcomes
J Patient Rep Outcomes
9
1
10.1186/s41687-025-00909-x
eng
2,025
6
16
2,025
6
16
[OBJECTIVE] to confirm the validity of the Comprehensive Score for Financial Toxicity (COST) Scale in Chinese patients with wet age-related macular degeneration. [METHODS] A tertiary hospital in Wuxi's ophthalmology outpatient clinic treated 217 patients with wet age-related macular degeneration (wAMD) were chosen usin...
Financial toxicity; Reliability; Validity; Wet age-related macular degeneration
0.93
35
Health Informatics; Health Information Management
Health Professions; Medicine
2,024
40,522,526
Fractional carbon dioxide laser assisted delivery of tranexamic acid versus ascorbic acid in the treatment of melasma: a split face comparative study with digital skin analysis.
Lasers in medical science
Lasers Med Sci
40
1
10.1007/s10103-025-04529-1
eng
2,025
6
16
2,025
6
16
[PURPOSE] Melasma is a chronic, acquired disorder of focal hypermelanosis. It clinically presents as hyperpigmented patches over photo-exposed areas such as the face. The study aimed to evaluate the efficacy and safety of combined fractional CO2 laser with topical tranexamic acid (TA) versus combined fractional CO2 las...
Laser; Melasma; Pigmentary disorders; Skin
0.625
88
Dermatology; Surgery
Medicine
2,024
40,522,427
Prevalence of Alzheimer's Disease and Cardiometabolic Multimorbidity in Older Adults Aged 60 and above in a Large-Scale Representative Sample in Türkiye: A Nationwide Population-Based Cross-Sectional Study.
Journal of epidemiology and global health
J Epidemiol Glob Health
15
1
10.1007/s44197-025-00435-5
eng
2,025
6
16
2,025
6
16
[BACKGROUND] It is a well-established fact that Alzheimer's Disease (AD) is a growing public health challenge worldwide, with increasing prevalence among older adults. Cardiometabolic multimorbidity (CMM) and various sociodemographic and lifestyle factors are acknowledged to influence AD risk. This study aimed to estim...
Cardiometabolic multimorbidity; Older adults; Population-based; Risk factors
1.014
41
Epidemiology
Medicine
2,024
40,522,352
Carbapenemase type and mortality in blood-stream infections caused by carbapenemase-producing enterobacterales: a multicenter retrospective cohort study.
Infection
Infection
null
null
10.1007/s15010-025-02584-y
eng
2,025
6
16
2,025
6
16
[BACKGROUND] Previous studies analyzing differences in mortality associated with carbapenemase type in patients with a variety of infections caused by carbapenemase-producing Enterobacterales (CPE) have produced conflicting results. [METHODS] We performed a multinational multicenter retrospective cohort study. Adult pa...
Aztreonam; Blood-stream infection; CPE; Ceftazidime-avibactam; Colistin; KPC; NDM
1.167
94
Infectious Diseases; Medicine; Microbiology
Medicine
2,024
40,522,177
Management of severe gingival recession using a double papilla connective tissue graft: A 2-year follow-up case study.
Clinical advances in periodontics
Clin Adv Periodontics
null
null
10.1002/cap.10368
eng
2,025
6
16
2,025
6
16
[BACKGROUND] This case study presents the treatment of a 7 mm deep and 5 mm wide RT1 gingival recession on the mandibular left canine in a 30-year-old systemically and periodontally healthy female, with the defect being associated with a self-injurious habit. [METHODS] Following counseling, self-injurious habit cessati...
case study; gingival recession; plastic surgery procedures; surgical flaps; tissue transplantation; ultrasonography
0.316
9
Periodontics; Medicine
Dentistry; Medicine
2,024
40,522,143
Comparison of Intradermal Versus Microneedling-Assisted Botulinum A Toxin Injection for Enlarged Facial Pores: A Randomized Clinical Trial.
Journal of cosmetic dermatology
J Cosmet Dermatol
24
6
10.1111/jocd.70114
eng
2,025
6
null
null
null
null
[BACKGROUND] Enlarged facial pores are a prevalent cosmetic concern affecting many individuals. Traditional treatments include topical agents and laser therapies, but recent advancements have introduced intradermal and microneedling-assisted Botulinum toxin type A (BoNTA) injections as promising alternatives. This stud...
botulinum toxins; cosmetic techniques; intradermal injections; microneedling; skin pores; type A
0.764
67
Dermatology
Medicine
2,024
40,521,902
Associations Between Tumor Characteristics, Postoperative Complications, and Early Versus Late Discharge After Endoscopic Endonasal Pituitary Adenoma Resection.
Operative neurosurgery (Hagerstown, Md.)
Oper Neurosurg
null
null
10.1227/ons.0000000000001667
eng
2,025
6
16
2,025
6
16
[BACKGROUND AND OBJECTIVES] Enhanced recovery after surgery protocols have resulted in a paradigm change in perioperative care with applications in cranial neurosurgery. Protocols have been implemented to increase rates of early discharge with length of stay being an important metric after pituitary adenoma (PA) resect...
Complications; Early discharge; Endoscopic endonasal surgery; Neurosurgery; Pituitary adenoma; Preoperative symptoms; Recurrence
0.557
44
Surgery; Neurology
Medicine
2,024
40,521,790
Impact of substance use and trauma on postpartum readmission rates and hospitalization costs: An observational study.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Int J Gynaecol Obstet
null
null
10.1002/ijgo.70299
eng
2,025
6
16
2,025
6
16
[INTRODUCTION] Substance use disorder (SUD) has been seen to be a contributing factor in the rise in maternal morbidity and mortality in the United States, and more information is needed regarding the impact of SUD on peripartum outcomes. We hypothesized that patients with an SUD diagnosis at the time of delivery would...
healthcare utilization; hospital readmissions; peripartum; postpartum; substance use; trauma
null
null
null
null
null
40,521,354
Visceral fat-to-muscle ratio guides spontaneous closure in post-sepsis duodenal fistula: a body composition divergence beyond visceral-subcutaneous fat ratio.
Frontiers in nutrition
Front Nutr
12
null
10.3389/fnut.2025.1604230
eng
2,025
null
null
2,025
5
30
[BACKGROUND] This study aimed to investigate whether body composition parameters (visceral fat area/total abdominal muscle area index, VFA/TAMAI; visceral-to-subcutaneous fat ratio, VFA/SFA) predict spontaneous closure in duodenal fistula patients after sepsis resolution. [METHODS] A multicenter retrospective study enr...
body composition; duodenal fistula; sepsis; spontaneous closure; visceral fat area
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
40,521,048
Dynamic mitral regurgitation unmasked by handgrip exercise is linked with outcomes in (non-) dilated cardiomyopathy.
International journal of cardiology. Heart vasculature
Int J Cardiol Heart Vasc
59
null
10.1016/j.ijcha.2025.101715
eng
2,025
8
null
2,025
6
2
[BACKGROUND] Recent studies suggest that secondary mitral regurgitation (MR) is a dynamic condition influenced by global and regional left ventricular (LV) remodeling as well as by mitral valvular deformation. Exercise testing is crucial in assessing the hemodynamic relevance of MR and is recommended by current guideli...
null
null
null
null
null
null
40,520,802
Association between the atherogenic index of plasma and mortality in the chronic kidney disease population: evidence from NHANES.
Frontiers in medicine
Front Med (Lausanne)
12
null
10.3389/fmed.2025.1575657
eng
2,025
null
null
2,025
5
30
[BACKGROUND] The atherosclerosis index (AIP) in plasma is a novel indicator closely associated with various metabolic abnormalities, and the bidirectional relationship between metabolic dysfunction and chronic kidney disease (CKD) has been extensively documented. However, evidence regarding the association between AIP ...
National Health and Nutrition Examination Survey; atherogenic index of plasma; cardiovascular disease; chronic kidney disease; mortality; prognosis
0.962
102
Medicine
Medicine
2,024
40,520,754
Total Knee Arthroplasty following Genicular Artery Embolization: A Case Report.
Journal of orthopaedic case reports
J Orthop Case Rep
15
6
10.13107/jocr.2025.v15.i06.5688
eng
2,025
6
null
null
null
null
[INTRODUCTION] The literature on total knee arthroplasty following genicular artery embolization (GAE) is still in its early stages. This case highlights the challenges and essential considerations in performing total knee arthroplasty for advanced osteoarthritis (OA) in patients who experience inadequate pain relief f...
Genicular artery embolization; osteoarthritis; total knee arthroplasty
null
null
null
null
null
40,520,607
Glucose-potassium ratio: a prognostic biomarker enhancing outcome prediction in mild-to-moderate traumatic brain injury.
Frontiers in neurology
Front Neurol
16
null
10.3389/fneur.2025.1577390
eng
2,025
null
null
2,025
5
30
[BACKGROUND] To determine the prognostic value of the serum glucose-to-potassium ratio (GPR) in patients with mild-to-moderate traumatic brain injury (MM-TBI). [METHODS] Clinical data from patients admitted to the Second Affiliated Hospital of Fujian Medical University with MM-TBI between January 1, 2018 and December 3...
mild-to-moderate traumatic brain injury; prognosis; propensity score matching; receiver operating characteristic; restricted cubic spline; serum glucose and potassium ratio
0.993
118
Neurology; Neurology
Medicine; Neuroscience
2,024
40,520,530
Blood essential trace elements and Alzheimer's disease biomarkers in midlife.
Frontiers in aging neuroscience
Front Aging Neurosci
17
null
10.3389/fnagi.2025.1539749
eng
2,025
null
null
2,025
5
30
[BACKGROUND] Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, impacting millions globally. Essential trace elements are implicated in key age-related physiologic processes but have not been fully examined with respect to AD etiology. This study investigates associ...
amyloid-beta; biomarkers; tau; trace elements
1.479
135
Cognitive Neuroscience; Aging
Biochemistry, Genetics and Molecular Biology; Neuroscience
2,024
40,520,437
Developing a Family Medicine Program in Jordan: appraisal of trainees and trainers and final assessment outcomes.
MedEdPublish (2016)
MedEdPublish (2016)
14
null
10.12688/mep.20687.3
eng
2,024
null
null
2,025
4
29
[INTRODUCTION] Curriculum development in medical education, particularly in family medicine, is essential for preparing healthcare professionals to meet evolving patient needs. This article examines the development of a Family Medicine program in Jordan, focusing on challenges, methodologies, and outcomes. [METHODS] Th...
Curriculum Development; Family Medicine Education; Transcultural Collaboration
null
null
null
null
null
40,520,340
Correlation between albumin levels during the third trimester and the risk of postpartum levator ani muscle rupture.
Open medicine (Warsaw, Poland)
Open Med (Wars)
20
1
10.1515/med-2025-1209
eng
2,025
null
null
2,025
6
9
[OBJECTIVE] To investigate the correlation between albumin levels during the third trimester and the risk of postpartum levator ani muscle rupture. [METHODS] A retrospective analysis of 410 parturients undergoing vaginal delivery at Zhangzhou Hospital Affiliated to Fujian Medical University was conducted. Parturients w...
albumin levels; levator ani muscle rupture; postpartum; risk factors; week before delivery
0.116
36
Medicine
Medicine
2,023
40,520,121
Allergic-related skin diseases: Global disease burden from 1990 to 2021 and future trends.
The World Allergy Organization journal
World Allergy Organ J
18
7
10.1016/j.waojou.2025.101072
eng
2,025
7
null
2,025
6
3
[BACKGROUND] Allergic-related skin diseases, including atopic dermatitis (AD), urticaria, and contact dermatitis (CD), are significant global public health challenges. Currently, there is a lack of systematic analysis of allergic-related skin diseases globally. [METHODS] This study aimed to quantify the global burden o...
Allergic-related skin diseases; Atopic dermatitis; Contact dermatitis; Global burden of disease; Urticaria
1.273
62
Pulmonary and Respiratory Medicine; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,520,033
Mitigating the Oncogenic Roles of miR-629-5p and miR-660-5p Through Direct Binding by Two Potential Drug Targets for Colorectal Cancer Prevention.
International journal of preventive medicine
Int J Prev Med
16
null
10.4103/ijpvm.ijpvm_277_24
eng
2,025
null
null
2,025
5
28
[BACKGROUND] Many studies have reported the oncogenic roles of microRNA (miRNA)-629-5p and miRNA-660-5p in various cancers. This study aimed to elucidate the oncogenic roles of miRNA-629-5p and miRNA-660-5p, focusing on their potential contributions to early colorectal cancer (CRC) detection. Additionally, this researc...
miR-629-5p; miR-660-5p; molecular docking; molecular dynamics simulation; regorafenib
0.607
60
Public Health, Environmental and Occupational Health
Medicine
2,024
40,519,707
An Australasian Survey of Neonatal Clinicians on Clinical Utility of Point-of-Care Bowel Ultrasound in Diagnosis of Necrotising Enterocolitis.
Australasian journal of ultrasound in medicine
Australas J Ultrasound Med
28
3
10.1002/ajum.70007
eng
2,025
8
null
2,025
6
13
[INTRODUCTION] Necrotising enterocolitis (NEC) is a life-threatening intestinal disease of the newborn characterised by ischaemia, inflammation and bowel necrosis. Due to the lack of biochemical markers and nonspecific clinical signs in early NEC, bowel ultrasound has gained popularity as a diagnostic tool. This survey...
bowel ultrasound; necrotising enterocolitis
null
null
null
null
null
40,519,671
Left Ventricular Ejection Fraction and Previous Cardiac Revascularization: Impact on Patient Survival, Graft Survival, and Complications in Kidney Transplant Recipients.
Transplantation direct
Transplant Direct
11
7
10.1097/TXD.0000000000001802
eng
2,025
7
null
2,025
6
12
[BACKGROUND] Kidney transplant physicians believe that the cardiac status of kidney transplant recipients influences posttransplant outcomes. However, the Scientific Registry of Transplant Recipients (SRTR) does not include cardiac variables in its risk-adjustment model, raising the question of whether it fairly risk a...
null
0.694
35
Transplantation
Medicine
2,024
40,519,356
Effectiveness of stress management and relaxation interventions for management of hypertension and prehypertension: systematic review and network meta-analysis.
BMJ medicine
BMJ Med
4
1
10.1136/bmjmed-2024-001098
eng
2,025
null
null
2,025
4
8
[OBJECTIVE] To assess whether relaxation and stress management techniques are useful in reducing blood pressure in individuals with hypertension and prehypertension. [DESIGN] Systematic review and network meta-analysis. [DATA SOURCES] Medline, PsycInfo, and CENTRAL (Cochrane Central Register of Controlled Trials) from ...
Hypertension
null
null
null
null
null
40,519,225
Disease-free survival as a surrogate for overall survival in early-stage pancreatic cancer trials: a correlation meta-analysis.
BMJ oncology
BMJ Oncol
4
1
10.1136/bmjonc-2025-000766
eng
2,025
null
null
2,025
5
6
[OBJECTIVE] Disease-free survival (DFS) is frequently used as the primary endpoint in trials of adjuvant and neoadjuvant therapies for early-stage pancreatic cancer (PC), but its validity as a surrogate for overall survival (OS) remains uncertain. This study evaluates the strength and consistency of DFS as a surrogate ...
Adjuvant therapy; Pancreatic cancer
1.731
6
Oncology
Medicine
2,024
40,518,975
Co-design of interventions and services with structurally marginalized populations in the context of maternal and early childhood primary care: a rapid scoping review.
Primary health care research development
Prim Health Care Res Dev
26
null
10.1017/S146342362510011X
eng
2,025
6
16
2,025
6
16
[AIM] To synthesize evidence on approaches used in the co-design of maternal and early childhood primary care interventions with structurally marginalized populations. [BACKGROUND] Involving end-users when developing health interventions can enhance outcomes. There is limited knowledge on how to effectively engage stru...
co-design; early childhood; marginalization; maternal child health; primary care; social isolation
null
null
null
null
null
40,518,676
Parenteral nutrition weaning in pediatric intestinal failure patients enrolled in remote patient monitoring: A descriptive study.
JPEN. Journal of parenteral and enteral nutrition
JPEN J Parenter Enteral Nutr
49
6
10.1002/jpen.2784
eng
2,025
8
null
2,025
6
15
[BACKGROUND] Remote patient monitoring (RPM) enhances patient surveillance. This study describes our initial experience with RPM in pediatric intestinal failure patients and its preliminary impact on parenteral nutrition (PN) reduction in an outpatient setting. [METHODS] We performed a descriptive cohort study on pedia...
home parenteral nutrition; intestinal failure; intestinal rehabilitation; pediatrics
null
null
null
null
null
40,518,343
Identification of risk factors for permanent visual loss in patients with giant cell arteritis.
European journal of internal medicine
Eur J Intern Med
null
null
10.1016/j.ejim.2025.06.001
eng
2,025
6
14
2,025
6
14
[OBJECTIVES] permanent visual loss (PVL) is the most frequent ischemic complication of GCA. We aimed to evaluate whether clinical signs, symptoms, and blood test abnormalities at GCA diagnosis can predict PVL. [PATIENTS AND METHODS] retrospective, multicenter study of patients with biopsy-proven GCA. The whole cohort w...
Giant cell arteritis; Inflammatory markers; Permanent visual loss; Systemic symptoms
1.166
98
Internal Medicine
Medicine
2,024
40,517,678
Early diagnosis and delayed treatment of anorectal melanoma in a 19-year-old female: A case report.
International journal of surgery case reports
Int J Surg Case Rep
132
null
10.1016/j.ijscr.2025.111518
eng
2,025
7
null
2,025
6
14
[INTRODUCTION AND IMPORTANCE] Anorectal melanoma is a rare and aggressive malignancy, accounting for less than 1 % of all melanoma cases and less than 0.5 % of anal canal malignancies. It typically occurs in the 6[th] and 8[th] decades of life. The diagnosis is often delayed due to non-specific symptoms, resulting in m...
Abdominoperineal resection; Anorectal melanoma; Case report; Melanoma; Polyp
0.238
31
Surgery
Medicine
2,024
40,517,366
Trends of aortic valve-preserving surgery in japan: an updated five-year nationwide survey.
General thoracic and cardiovascular surgery
Gen Thorac Cardiovasc Surg
null
null
10.1007/s11748-025-02170-x
eng
2,025
6
15
2,025
6
15
[OBJECTIVE] We evaluated trends and outcomes of aortic valve-preserving surgery (AVPS) in Japan, particularly with regard to aortic regurgitation (AR), in comparison with data from 2014. [METHODS] We conducted a nationwide survey across 244 hospitals in Japan, focusing on aortic valve and aortic root surgeries performe...
Aortic regurgitation; Aortic valve repair; Reimplantation; Remodeling; Valve-sparing root replacement
0.423
50
Surgery; Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,024
40,517,267
Fatty acid metabolism of granulose cells and follicular fluid and their associations with embryo quality in normal-weight women with PCOS.
Journal of ovarian research
J Ovarian Res
18
1
10.1186/s13048-025-01711-5
eng
2,025
6
14
2,025
6
14
[BACKGROUND] Polycystic ovary syndrome (PCOS) is the most common reproductive-endocrine disorder in women of reproductive age. The granulosa cell metabolism correlated with oocyte competence. However, the alteration of fatty acid in granulosa cell of PCOS patients is unclear. Besides, obesity per se is related to dysfu...
Fatty acid; Granulosa cell; PCOS; Proteomics
1.099
66
Obstetrics and Gynecology; Oncology
Medicine
2,024
40,517,256
Modelling the risk factors associated with female genital mutilation among the under-five children in Ethiopia, a retrospective study.
Journal of health, population, and nutrition
J Health Popul Nutr
44
1
10.1186/s41043-025-00962-8
eng
2,025
6
14
2,025
6
14
[BACKGROUND] Female Genital Mutilation (FGM) also referred to as female genital cutting or female circumcision, has become a global health concern. It is a deeply entrenched traditional practice involving partial or total removal of the external female genitalia for non-medical reasons. To inform effective policymaking...
Ethiopia; Female genital mutilation; Maternal and child health; Time-to-circumcision
0.737
79
Food Science; Health, Toxicology and Mutagenesis; Public Health, Environmental and Occupational Health
Agricultural and Biological Sciences; Environmental Science; Medicine
2,024
40,517,230
Validation of a food security experience scale among indigenous populations in Brazil.
International journal for equity in health
Int J Equity Health
24
1
10.1186/s12939-025-02515-1
eng
2,025
6
15
2,025
6
15
[BACKGROUND] Assessing food and nutrition security among indigenous populations in Brazil is challenging due to their significant cultural and linguistic diversity. This study aimed to validate a national food insecurity measurement scale for indigenous peoples in Brazil (EBIA-I). [METHODS] A total of 495 indigenous ho...
Brazil; Food security; Indigenous peoples; Measurement; Scale; Validation
1.707
93
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,024
40,516,947
Identification of genetic variants in patients with primary and secondary amenorrhea.
Saudi medical journal
Saudi Med J
46
6
10.15537/smj.2025.46.6.20250205
eng
2,025
6
null
null
null
null
[OBJECTIVES] To identify the cytogenetic and molecular pattern abnormalities and early diagnose the cause of primary and secondary amenorrhea. [METHODS] A total of 320 patients in the age group of 14-35 years with clinically confirmed amenorrhea were screened using conventional cytogenetic methods. Patients with a norm...
amenorrhea; chromosomal abnormalities; chromosomal microarray; clinical exome sequencing; karyotyping
null
null
null
null
null
40,516,703
Disparities in Access to High-volume Centers for Muscle Invasive Bladder Cancer and Its Association With Treatment Patterns and Outcomes.
Urology
Urology
null
null
10.1016/j.urology.2025.06.021
eng
2,025
6
12
2,025
6
12
[OBJECTIVE] To investigate access to high-volume centers (HVCs) for nonmetastatic muscle-invasive bladder cancer (MIBC) and assesses implications of disparities on treatment outcomes. We hypothesized that socially disadvantaged patients would have limited access to HVCs, contributing to observed outcome disparities. [M...
null
0.756
197
Urology
Medicine
2,024
40,516,291
Influence of caregiver knowledge of home asthma management on health outcomes of children in low- and middle-income countries: A systematic review.
Journal of pediatric nursing
J Pediatr Nurs
84
null
10.1016/j.pedn.2025.06.019
eng
2,025
6
13
2,025
6
13
[BACKGROUND] Low- and Middle-income Countries (LMICs) bear the highest burden of childhood asthma globally. More than 90 % of asthma-related deaths and 84 % of disability-adjusted life-years associated with childhood asthma occur in LMICs. To reduce the overall burden of childhood asthma in LMICs, concerted efforts hav...
Asthma; Caregivers; Children; Health outcomes; Home management; Knowledge; Low- and middle-income countries
0.798
78
Pediatrics
Nursing
2,024
40,516,205
GTN misdiagnosed as ectopic pregnancy: a 17-year retrospective cohort study.
Gynecologic oncology
Gynecol Oncol
199
null
10.1016/j.ygyno.2025.06.010
eng
2,025
6
13
2,025
6
13
[OBJECTIVE] To evaluate the effect of misdiagnosis on the chemotherapy response and prognosis of gestational trophoblastic neoplasia (GTN), and to explore strategies to enhance precision management of uncertain GTN. [METHODS] GTN patients misdiagnosed as ectopic pregnancies were retrospectively enrolled. GTN without mi...
Chemotherapy resistance; Ectopic pregnancy; Gestational trophoblastic neoplasia; Misdiagnosis
1.881
192
Obstetrics and Gynecology; Oncology
Medicine
2,024
40,516,199
Exploring the chemotherapeutic potential of diosmetin ruthenium-p-cymene complex in bladder cancer treatment through the regulation of the PI3K/β-catenin/TJP1/AR signaling pathway.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
J Trace Elem Med Biol
90
null
10.1016/j.jtemb.2025.127680
eng
2,025
8
null
2,025
6
6
[BACKGROUND] Bladder cancer is the deadliest cause of cancer-related morbidity worldwide. The metal-flavonoid compound, diosmetin ruthenium-p-cymene complex, demonstrated a remarkable toxicological profile in different toxicological and genotoxicological studies. In this context, the study aimed to explore the chemothe...
Apoptosis; Bladder carcinoma; Chemotherapy; Diosmetin ruthenium-p-cymene complex; In vitro; In vivo
0.743
98
Inorganic Chemistry; Biochemistry; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Chemistry
2,024
40,516,134
Dimethyloxalylglycine regulates osteogenesis of dental pulp stem cells through PI3K/AKT signaling pathways.
Tissue cell
Tissue Cell
96
null
10.1016/j.tice.2025.103012
eng
2,025
6
10
2,025
6
10
[BACKGROUND] Dental pulp mesenchymal stem cells (DPSCs) are typically cultivated in vitro under normoxic conditions, which may adversely affect their biological functions during research and treatment. Dimethyloxalylglycine (DMOG) is a small-molecule drug that has demonstrated impressive therapeutic outcomes in conditi...
Angiogenesis; Dental pulp mesenchymal stem cells; Dimethyloxalylglycine; Hypoxia; Normoxia; Osteogenesis
null
null
null
null
null
40,515,798
Psychometric analysis of the Neuro-QoL Fatigue in generalized Myasthenia Gravis (gMG) using data from a phase 3 trial.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Qual Life Res
null
null
10.1007/s11136-025-03998-9
eng
2,025
6
14
2,025
6
14
[OBJECTIVES] To evaluate the psychometric properties of the Neuro-QoL Fatigue patient-reported outcome measure and its short form when used to assess fatigue in adults living with generalized Myasthenia Gravis (gMG). [METHODS] Data from Vivacity-MG3 (ClinicalTrials.gov Identifier: NCT04951622), a double-blind placebo-c...
Fatigue; Generalized myasthenia gravis; Neuro-QoL fatigue; Psychometrics; Scale validation
1.436
179
Public Health, Environmental and Occupational Health
Medicine
2,024
40,515,785
Long-read 16S amplicon analyses and improved cultivation techniques as joined approach for the identification of viable bacterial populations in silage.
Journal of applied microbiology
J Appl Microbiol
136
7
10.1093/jambio/lxaf151
eng
2,025
7
1
null
null
null
[AIMS] Lactic acid bacteria (LAB) are crucial for the quality and preservation of silage. Exploration and isolation of the key microbiome are important for improving fermentation processes. While cultivation-dependent methods enable the isolation of LAB, they often overlook organisms with challenging cultivation requir...
agriculture microbiology; amplicon sequencing; isolation; lactic acid bacteria; microbiome
0.779
195
Applied Microbiology and Biotechnology; Biotechnology; Medicine
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,024
40,515,674
Antifungal therapy in Candida infective endocarditis: a comparison of echinocandins and other treatment regimens in a nation-wide cohort study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clin Infect Dis
null
null
10.1093/cid/ciaf312
eng
2,025
6
14
2,025
6
14
[BACKGROUND] Amphotericin B-based treatment has been the cornerstone of Candida infective endocarditis (CIE) treatment, but recent guidelines also recommend echinocandins. However, there is limited outcome data. The few studies performed report differing results. The aim of this study was to compare the outcome with ec...
Candida; amphotericin B; azoles; echinocandins; infective endocarditis
2.992
398
Infectious Diseases; Microbiology
Medicine
2,024
40,515,562
Endoscopic resection for gastric subepithelial tumours: a retrospective cohort study.
Annals of medicine
Ann Med
57
1
10.1080/07853890.2025.2514788
eng
2,025
12
null
2,025
6
14
[OBJECTIVE] Although endoscopic resection (ER) is an established technique for gastric subepithelial tumours (SETs), comprehensive data on its efficacy and safety remain limited. This study aimed to evaluate the efficacy and safety of ER in patients with gastric SETs and to identify risk factors associated with procedu...
Endoscopic resection; adverse outcomes; efficacy; safety; subepithelial tumours
1.204
133
Medicine
Medicine
2,024
40,515,536
Prevalence of Over-the-Counter Drug Abuse and Associated Psychosocial Factors Among High School Students: A Nationwide Cross-Sectional Survey in Japan.
Neuropsychopharmacology reports
Neuropsychopharmacol Rep
45
2
10.1002/npr2.70030
eng
2,025
6
null
null
null
null
[AIM] This study estimated the prevalence of over-the-counter (OTC) drug abuse among high school students in Japan and clarified the predictors related to their school and home life. [METHODS] A nationwide cross-sectional survey was conducted between September 2021 and March 2022. The survey included 41 357 valid respo...
adolescent; epidemiologic research design; nonprescription drugs; social isolation
0.602
24
Clinical Psychology; Pharmacology; Pharmacology; Psychiatry and Mental Health
Medicine; Pharmacology, Toxicology and Pharmaceutics; Psychology
2,024
40,515,396
Uncovering metabolic pathways in human alveolar macrophages in response to lipopolysaccharide.
Clinical and experimental immunology
Clin Exp Immunol
219
1
10.1093/cei/uxaf028
eng
2,025
1
21
null
null
null
[INTRODUCTION] Alveolar macrophages (AMs) play an essential role in maintaining homeostasis in the lung and in innate immunity for host defense. To fuel inflammatory responses, AMs do not rely on glycolysis, but require oxidative phosphorylation. However, which nutrients AMs use to fuel their energy demand during infla...
cellular immunology; lipopolysaccharide; macrophage; metabolism
null
null
null
null
null
40,514,742
Anti-melanoma differentiation-associated gene 5 antibody associated rapidly progressive interstitial lung disease in a pediatric patient: a case report.
Journal of medical case reports
J Med Case Rep
19
1
10.1186/s13256-025-05336-6
eng
2,025
6
13
2,025
6
13
[BACKGROUND] Rapidly progressive interstitial lung disease presents as a severe complication of juvenile dermatomyositis, particularly when associated with anti-melanoma differentiation-associated gene 5. We report a pediatric case that underscores the necessity for clinicians to maintain a high index of suspicion for ...
Anti-MDA5 antibody; Case report; ECMO; Extracorporeal membrane oxygenation; ILD; Interstitial lung disease in children; JDM; Juvenile dermatomyositis; Rapidly progressive interstitial lung disease
0.31
43
Medicine
Medicine
2,024
40,514,683
Real-time changes in pulse pressure during a 10-second end-expiratory occlusion test reliably detect preload responsiveness.
Critical care (London, England)
Crit Care
29
1
10.1186/s13054-025-05483-8
eng
2,025
6
13
2,025
6
13
[BACKGROUND] The end-expiratory occlusion (EEO) test detects preload responsiveness through changes in cardiac index (ΔCI) during a 15-second respiratory hold at end-expiration. We investigated the diagnostic accuracy of EEO-induced changes in arterial pulse pressure (∆PP), especially when the duration of EEO is reduce...
Cardiac output; Fluid challenge; Fluid responsiveness; Haemodynamic monitoring; Passive leg Raising
2.738
229
Critical Care and Intensive Care Medicine
Medicine
2,024
40,513,907
Factors Contributing to the Progression of Osteoarthritis After Rotational Acetabular Osteotomy: A Study of 183 Hips With a Median Follow-Up Period of 14 Years.
The Journal of arthroplasty
J Arthroplasty
null
null
10.1016/j.arth.2025.06.021
eng
2,025
6
11
2,025
6
11
[BACKGROUND] Rotational acetabular osteotomy (RAO) is a joint-preserving procedure that improves femoral head coverage. This procedure is expected to counteract the progression of secondary osteoarthritis of the hip (OA) in young patients who have developmental dysplasia of the hip (DDH). However, postoperative OA prog...
body mass index; developmental dysplasia of the hip; osteoarthritis; rotational acetabular osteotomy; total hip arthroplasty
1.951
171
Orthopedics and Sports Medicine
Medicine
2,024
40,513,308
Health-related quality of life in patients with Camurati-Engelmann disease: A case series study.
Medicina clinica
Med Clin (Barc)
165
4
10.1016/j.medcli.2025.107043
eng
2,025
6
12
2,025
6
12
[BACKGROUND] Camurati-Engelmann disease (CED) is an extremely rare autosomal dominant bone dysplasia characterized by hyperostosis of the long bones and, in severe cases, of the skull and axial skeleton. This study aims to analyze the impact on quality of life in a non-selected group of CED patients. [METHODS] This mon...
Calidad de vida; Displasia diafisaria progresiva; Enfermedad de Camurati-Engelmann; Mental health; Physical health; Progressive diaphyseal dysplasia; Quality of life; SF12; Salud mental
0.383
74
Medicine
Medicine
2,024
40,513,233
Minimum clinically important difference, substantial clinical benefit, and patient acceptable symptomatic state for patients with spinal metastasis who underwent surgical treatment: a multicenter prospective clinical study.
Journal of neurosurgery. Spine
J Neurosurg Spine
null
null
10.3171/2025.3.SPINE241329
eng
2,025
6
13
2,025
6
13
[OBJECTIVE] There is increasing emphasis on patient-reported outcomes (PROs) in assessing surgical efficacy, especially in patients with spinal metastasis (SM). The updated version of the Spine Oncology Study Group Outcomes Questionnaire (SOSGOQ 2.0) is a disease-specific tool, while the EQ-5D-5L is a general quality-o...
minimal clinically important difference; oncology; patient acceptable symptomatic state; patient-reported outcomes; spinal metastasis; substantial clinical benefit
null
null
null
null
null
40,513,089
Factors Associated With the Level of Trust in Health Information Robots Among the General Population From a Socioecological Model Perspective: Network Analysis.
Journal of medical Internet research
J Med Internet Res
27
null
10.2196/68299
eng
2,025
6
13
2,025
6
13
[BACKGROUND] Although robots have emerged as a new means of delivering health information, with the advancement of artificial intelligence technology, individuals still face challenges in deciding whether to trust the health information provided by these robots owing to various trust-related factors. [OBJECTIVE] This s...
artificial intelligence; health information; network analysis; robots; socioecological model
1.992
214
Health Informatics
Medicine
2,024
40,512,365
Curcumin Ameliorates Cisplatin-Induced Cardiovascular Injuries by Upregulating ERK/p-ERK Expression in Rats.
Chinese journal of integrative medicine
Chin J Integr Med
31
8
10.1007/s11655-025-4017-4
eng
2,025
8
null
2,025
6
13
[OBJECTIVE] To investigate cisplatin-induced cardiovascular toxicity and explore the protective effects and potential mechanism of curcumin co-treatment. [METHODS] Forty adult male Sprague-Dawley rats were numbered and randomly divided into control group, cisplatin group (7.5 mg/kg, once a week, for 2 weeks), curcumin ...
cardiovascular toxicity; cisplatin; curcumin; extracellular signal-regulated kinase
0.561
49
Complementary and Alternative Medicine; Medicine; Pharmacology
Medicine
2,024
40,512,267
Association between metabolic score for insulin resistance and hypertension in middle-aged and older adults: a nationwide cross-sectional and longitudinal study.
Aging clinical and experimental research
Aging Clin Exp Res
37
1
10.1007/s40520-025-03099-0
eng
2,025
6
13
2,025
6
13
[INTRODUCTION] Metabolic score for insulin resistance (METS-IR) is a promising and reliable non-insulin-based method for assessing insulin resistance and cardiovascular disease risk. Through cross-sectional and longitudinal analyses, we evaluated the predictive ability of METS-IR for hypertension risk, aiming to provid...
Hypertension; Incidence; Mets-IR; Prevalence
1.144
95
Aging; Geriatrics and Gerontology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,512,041
Comparison of ADMET profile between thiosemicarbazide and semicarbazide derivatives regarding anticancer properties.
Expert opinion on drug metabolism toxicology
Expert Opin Drug Metab Toxicol
21
8
10.1080/17425255.2025.2520561
eng
2,025
8
null
2,025
6
17
[INTRODUCTION] The incidence of cancer is constantly increasing, and current cytostatics are not effective enough and cause serious side effects. Thio/semicarbazide derivatives seem to be promising candidates for anticancer drugs. This systematic review aimed to analyze comparatively the ADMET profiles of thiosemicarba...
ADMET; cancer; drug discovery; semicarbazides; thiosemicarbazide
null
null
null
null
null
40,511,997
Bidirectional association of rheumatoid arthritis and inflammatory bowel diseases: a large-scale prospective cohort study.
Rheumatology (Oxford, England)
Rheumatology (Oxford)
null
null
10.1093/rheumatology/keaf337
eng
2,025
6
13
2,025
6
13
[OBJECTIVES] to investigate the bidirectional prospective association between inflammatory bowel disease (IBD) and rheumatoid arthritis (RA) in a large-scale, long-term follow-up, population-based cohort. [METHODS] Participants free of any cancer at baseline were included and divided into two prospective cohorts: basel...
cohort study; inflammatory bowel disease; rheumatoid arthritis
1.721
205
Pharmacology; Rheumatology
Medicine
2,024
40,561,523
BMI during childhood and puberty - associations with blood pressure and hypertension.
European journal of preventive cardiology
Eur J Prev Cardiol
null
null
10.1093/eurjpc/zwaf376
eng
2,025
6
25
2,025
6
25
[AIM] The present study aimed to evaluate the association between BMI during childhood and puberty and blood pressure and hypertension in midlife, and to explore midlife BMI as a potential mediator of these associations. [METHOD] We linked the BMI Epidemiology Study Gothenburg (BEST) with developmental BMI, with the Sw...
BMI; Puberty; adult; blood pressure; body mass index; cardiovascular disease; childhood; cohort study; risk factors
2.119
130
Cardiology and Cardiovascular Medicine; Epidemiology
Medicine
2,024
40,561,517
Sex-related Differences in Long-Term Quality of Life After Out-of-Hospital Cardiac Arrest: A Nationwide Cross-sectional Survey Study.
European heart journal. Acute cardiovascular care
Eur Heart J Acute Cardiovasc Care
null
null
10.1093/ehjacc/zuaf092
eng
2,025
6
25
2,025
6
25
[BACKGROUND] Sex differences in survival and short-term outcomes after out-of-hospital cardiac arrest (OHCA) are well-documented, but its impact on long-term health-related quality of life (HRQoL) is unclear. [METHODS] This cross-sectional survey study used the EuroQol Health Questionnaire (EQ-5D), the 12-Item Short Fo...
HRQol; Health-related quality of life; Long term quality of live; OHCA; Out of hospital cardiac arrest; Sex differences
null
null
null
null
null
40,561,184
Annual global dengue dynamics are related to multi-source factors revealed by a machine learning prediction analysis.
PLoS neglected tropical diseases
PLoS Negl Trop Dis
19
6
10.1371/journal.pntd.0013232
eng
2,025
6
null
2,025
6
25
[BACKGROUND] Dengue is a significant global health threat, transmitted by mosquitoes and influenced by multiple factors. A comprehensive analysis of the impact of these factors on dengue at a global scale is helpful for better understanding and effective control of dengue epidemics. [METHODS] This study employed machin...
null
1.37
172
Infectious Diseases; Pharmacology, Toxicology and Pharmaceutics; Public Health, Environmental and Occupational Health
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,561,067
Effect of high-intensity anaerobic exercise on electrocortical activity in athletes and non-athletes.
PloS one
PLoS One
20
6
10.1371/journal.pone.0310287
eng
2,025
null
null
2,025
6
25
[AIM] The present study aims to verify the information processing in athletes through electroencephalography, analyze cortical areas responsible for cognitive functions related to attentional processing of visual stimuli, and investigate motor activity's influence on cognitive aspects. Additionally, we aimed to analyze...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
40,560,365
Decoding Huntington's disease: a global survey on symptoms and genetic testing practices.
European archives of psychiatry and clinical neuroscience
Eur Arch Psychiatry Clin Neurosci
null
null
10.1007/s00406-025-02042-8
eng
2,025
6
25
2,025
6
25
[BACKGROUND] Huntington's disease (HD) is a fatal, autosomal dominant neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in the HTT gene. While chorea is the hallmark motor symptom, HD presents with diverse psychiatric and cognitive manifestations that usually precede motor onset. [METHODS] A 10-...
Genetic testing; HD; HD phenocopy; HD-like; Neurodegenerative disease
null
null
null
null
null
40,560,299
Evaluating the associations among asthma, asthma control and long COVID in U.S. adults.
Infection
Infection
null
null
10.1007/s15010-025-02588-8
eng
2,025
6
25
2,025
6
25
[OBJECTIVE] This study aimed to evaluate (1) the association between asthma and long COVID among U.S. adults and (2) the association between asthma control and long COVID among U.S. adults with asthma. [METHODS] Data from the 2023 National Health Interview Survey were used. Adults aged ≥ 18 years were included. Asthma ...
Asthma; Asthma control; COVID-19; Long COVID; National Health Interview Survey; Post COVID-19 condition
1.167
94
Infectious Diseases; Medicine; Microbiology
Medicine
2,024
40,560,121
Telemedicine and remote monitoring in neuromuscular diseases: Challenges and opportunities.
Journal of neuromuscular diseases
J Neuromuscul Dis
null
null
10.1177/22143602251330436
eng
2,025
6
25
2,025
6
25
[BACKGROUND] Telemedicine, the application of those information technologies to remotely provide health services either for synchronously catching or asynchronous monitoring patient medical data, has shown a growing and widespread application in several chronic diseases, and, especially during and after COVID-19 pandem...
digital tools; muscular dystrophy; neuromuscular diseases; neuropathies; telemedicine; telemonitoring
1.016
43
Neurology; Neurology
Medicine; Neuroscience
2,024
40,558,896
Antibacterial and Bactericidal Effects of the Er: YAG Laser on Oral Bacteria: A Systematic Review of Microbiological Evidence.
Journal of functional biomaterials
J Funct Biomater
16
6
10.3390/jfb16060209
eng
2,025
6
3
2,025
6
3
[BACKGROUND] The Er:YAG laser has gained attention in dentistry for its potential to enhance microbial disinfection through targeted photothermal and photoacoustic mechanisms. [OBJECTIVE] This systematic review aimed to evaluate the antibacterial and bactericidal efficacy of Er:YAG laser therapy across clinically relev...
Er:YAG laser; antimicrobial efficacy; biofilm removal; dental disinfection; endodontics; in vitro study; laser therapy; periodontology
0.87
52
Biomaterials; Biomedical Engineering
Engineering; Materials Science
2,024
40,558,577
Iodine Intake from Universal Salt Iodization Programs and Hashimoto's Thyroiditis: A Systematic Review.
Diseases (Basel, Switzerland)
Diseases
13
6
10.3390/diseases13060166
eng
2,025
5
23
2,025
5
23
[BACKGROUND] Hashimoto's thyroiditis (HT) is characterized by the loss of tolerance to thyroid autoantigens [thyroid peroxidase (TPO) and thyroglobulin (Tg)], usually identifying circulating antibodies (Abs) against these thyroid autoantigens (TPOAb and/or TgAb), together with a significant lymphocytic infiltration, ca...
Hashimoto; autoimmunity; iodine; prevalence; salt; thyroid
0.851
26
Medicine
Medicine
2,024
40,557,443
prospective multicenter validation of preoperative plasma ceramides as novel predictive biomarkers for clinically relevant post-hepatectomy liver failure.
International journal of surgery (London, England)
Int J Surg
null
null
10.1097/JS9.0000000000002791
eng
2,025
6
24
2,025
6
24
[BACKGROUND] Circulating ceramides (CERs) are associated with liver diseases and dysfunction. The utility of plasma CERs in predicting post-hepatectomy liver failure (PHLF) remains unclear. This study aimed to evaluate the clinical utility of preoperative plasma CERs for predicting clinically relevant PHLF (CR-PHLF). [...
biomarker; ceramides; nomogram; post-hepatectomy liver failure
2.076
99
Medicine; Surgery
Medicine
2,024
40,557,228
A single-institution retrospective analysis on the administration of β-lactam antibiotics prior to vancomycin in bacteremic patients.
Proceedings (Baylor University. Medical Center)
Proc (Bayl Univ Med Cent)
38
4
10.1080/08998280.2025.2494488
eng
2,025
null
null
2,025
4
28
[BACKGROUND] The 2021 Surviving Sepsis Guidelines emphasize prompt antibiotic administration as a recommendation for septic patients. Instead of focusing solely on timing, we aimed to investigate whether the sequence of antibiotic administration influences mortality. [METHODS] This single-institution retrospective stud...
Antibiotics; bacteremia; mortality; sepsis
null
null
null
null
null
40,556,344
Anti-inflammatory and immunomodulatory effects of valproate and carbamazepine involve distinct signaling in human peripheral blood mononuclear cells.
Immunopharmacology and immunotoxicology
Immunopharmacol Immunotoxicol
47
4
10.1080/08923973.2025.2517634
eng
2,025
8
null
2,025
6
24
[OBJECTIVES] Epilepsy is a chronic neurological condition with complex etiopathogenesis, treated with antiepileptics. In addition to their ability to regulate the activation threshold of neurons, antiepileptics have demonstrated a potential in shaping inflammation and the immune response. The main objective of our stud...
Antiepileptics; T-helper response; human peripheral blood mononuclear cells; peroxisome proliferator-activated receptor gamma; proinflammatory cytokines
0.725
63
Medicine; Pharmacology; Toxicology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,556,331
Oncology Specialists' Perceptions and Insights Into Dihydropyrimidine Dehydrogenase Testing in Palestine.
Cancer reports (Hoboken, N.J.)
Cancer Rep (Hoboken)
8
6
10.1002/cnr2.70251
eng
2,025
6
null
null
null
null
[BACKGROUND] This study evaluated awareness, prevalence, and utilization of dihydropyrimidine dehydrogenase (DPD) testing and pharmacogenomics among oncologists, residents, and clinical pharmacists working in Palestinian hospitals. [AIM] This study aimed to assess the knowledge and opinions of HCPsspecializing in oncol...
cancer; capecitabine; fluoropyrimidines; genetic testing; pharmacogenomics
0.729
24
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,556,029
Aortic annulus reconstruction with bovine pericardium during aortic valve replacement for severe calcific aortic stenosis.
Journal of cardiothoracic surgery
J Cardiothorac Surg
20
1
10.1186/s13019-025-03505-8
eng
2,025
6
24
2,025
6
24
[OBJECTIVE] To explore the application and effect of aortic annulus reconstruction (AAR) with bovine pericardium during surgical aortic valve replacement (SAVR) for severe calcific aortic stenosis (AS). [METHODS] We retrospectively reviewed 12 patients with severe calcified AS who underwent bovine pericardium aortic an...
Aortic annular enlargement; Aortic annulus reconstruction; Aortic valve replacement; Bovine pericardial patch; Calcific aortic stenosis
0.485
61
Surgery; Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,024
40,555,901
LH-RH agonist monotherapy for androgen receptor-positive recurrent and/or metastatic salivary gland cancer: a retrospective study.
International journal of clinical oncology
Int J Clin Oncol
30
8
10.1007/s10147-025-02785-3
eng
2,025
8
null
2,025
6
24
[BACKGROUND] Although combination therapy consisting of a luteinizing hormone-releasing hormone (LH-RH) agonist and an Androgen receptor (AR) inhibitor has demonstrated promising clinical activity for recurrent and/or metastatic SGC (R/M SGC), few studies on LH-RH agonist monotherapy have been reported. [METHODS] We co...
Androgen receptor; Goserelin; Leuprorelin; Salivary gland cancer
0.936
78
Medicine; Surgery; Hematology; Oncology
Medicine
2,024
40,555,503
Utilisation of waterpipe tobacco imagery in cigarette advertising: a case study of American tobacco company and RJ Reynolds tobacco company.
Tobacco control
Tob Control
null
null
10.1136/tc-2024-058896
eng
2,025
6
24
2,025
6
24
[BACKGROUND] Tobacco companies employ various advertising methods, including immersive consumer experiences and cultural imagery, to promote their products. To our knowledge, no prior studies have explored how cigarette companies exploited perceptions of waterpipe tobacco in their marketing activities. [METHODS] We con...
Advertising and Promotion; Non-cigarette tobacco products; Tobacco industry; Tobacco industry documents
2.305
147
Health; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,024
40,555,420
Quality Improvement Reduces Excessive Serum Bilirubin Laboratory Draws in a Community Hospital Nursery.
Hospital pediatrics
Hosp Pediatr
15
7
10.1542/hpeds.2024-008180
eng
2,025
7
1
null
null
null
[BACKGROUND] Newborn jaundice is common and requires appropriate monitoring and treatment to prevent acute bilirubin encephalopathy and kernicterus. Minimizing total serum bilirubin (TsB) draws has many benefits, including decreasing blood loss and painful procedures, as well as saving time and costs. [OBJECTIVE] The o...
null
0.822
41
Pediatrics; Pediatrics, Perinatology and Child Health; Medicine
Medicine; Nursing
2,024
40,555,402
Exploring the Relationship Between Digital Health Literacy and Patterns of Telemedicine Engagement and Appointment Attendance Within an Urban Academic Hospital.
Applied clinical informatics
Appl Clin Inform
null
null
10.1055/a-2640-2742
eng
2,025
6
24
2,025
6
24
[BACKGROUND] Telemedicine use has surged since the COVID-19 pandemic, offering a convenient way for patients to access healthcare. Whereas digital literacy (general comfort with and ability to use digital tools) is necessary to utilize telemedicine, digital health literacy is a subset of this, focusing on the ability t...
null
0.843
47
Computer Science Applications; Health Informatics; Health Information Management
Computer Science; Health Professions; Medicine
2,024
40,555,227
Keep on Keeping on? Patient Factors Predicting Discontinuation in Alcohol Use Disorder Treatment.
Substance use misuse
Subst Use Misuse
null
null
10.1080/10826084.2025.2519404
eng
2,025
6
24
2,025
6
24
[BACKGROUND] A substantial portion of patients with alcohol use disorder (AUD) discontinue treatment. More knowledge of predictors of discontinuation is important for clinicians in preventing premature discontinuation and tailoring treatment to the patient. [AIM] To investigate predictors of completion versus discontin...
Alcohol use disorder; alcohol; cognitive impairment; outcome predictors; treatment outcome
null
null
null
null
null
40,554,829
Optimizing beat-wise input for arrhythmia detection using 1-D convolutional neural networks: A real-world ECG study.
Computer methods and programs in biomedicine
Comput Methods Programs Biomed
269
null
10.1016/j.cmpb.2025.108898
eng
2,025
9
null
2,025
6
18
[BACKGROUNDS AND OBJECTIVES] Cardiac arrhythmias, characterized by irregular heartbeats, are difficult to diagnose in real-world scenarios. Machine learning has advanced arrhythmia detection; however, the optimal number of heartbeats for precise classification remains understudied. This study addresses this using machi...
Arrhythmia detection; Beat-wise processing; Biosignal; Convolutional neural network (CNN); Electrocardiography (ECG)
1.13
150
Computer Science Applications; Health Informatics; Software
Computer Science; Medicine
2,024
40,554,515
Real-World Clinical Effectiveness and Safety of Vedolizumab and Ustekinumab in Biologic-Naive Patients With Crohn's Disease By Disease Location: Results from the EVOLVE Expansion Study.
Journal of clinical gastroenterology
J Clin Gastroenterol
null
null
10.1097/MCG.0000000000002186
eng
2,025
6
20
2,025
6
20
[GOALS] This analysis compared the real-world effectiveness and safety of vedolizumab versus ustekinumab in biologic-naive patients by CD location. [BACKGROUND] Crohn's disease (CD) location may affect disease course and treatment decisions. [STUDY] Medical charts of biologic-naive patients with CD aged 18 years or old...
biologics (IBD); disease location; inflammatory bowel disease; outcomes research
0.993
135
Gastroenterology
Medicine
2,024
40,554,136
Focus on epilepsy and epilepsy syndromes in children with autism spectrum disorders: a study of 74 patients.
Brain development
Brain Dev
47
4
10.1016/j.braindev.2025.104385
eng
2,025
8
null
2,025
6
18
[BACKGROUND] Epilepsy is a common finding in children with autism spectrum disorders (ASD), but few studies describe the characteristics of epilepsy in these children. Our study aimed to characterize the electroclinical features of children with ASD and epilepsy through a retrospective multicenter study. [MATERIAL AND ...
Autism spectrum disorders; Epilepsy; Outcome; Seizures; Treatment
null
null
null
null
null
40,553,932
Amiodarone Association With Severe Primary Graft Dysfunction and Vasoactive Inotropic Score After Heart Transplantation.
Journal of cardiac failure
J Card Fail
null
null
10.1016/j.cardfail.2025.05.015
eng
2,025
6
17
2,025
6
17
[BACKGROUND] The impact of amiodarone on severe primary graft dysfunction (PGD) and vasoactive inotropic scores (VISs) following heart transplantation (HT) is unclear. [METHODS AND RESULTS] We investigated these relationships through a retrospective study of 183 consecutive patients 18 years old who underwent isolated ...
null
2.16
127
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,553,645
Comparison of lymphovenous anastomosis and vascularized lymph node transfer in lymphedema treatment - a literature review.
Acta chirurgiae plasticae
Acta Chir Plast
67
1
10.48095/ccachp202542
eng
2,025
null
null
null
null
null
[BACKGROUND] Lymphovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT) are both accepted microsurgical treatment options for lymphedema. This article summarises and analyses recent data on outcomes associated with LVA and VLNT for lymphedema treatment at varying degrees of severity. [METHODS] Literatur...
Lymphedema
null
null
null
null
null
40,553,470
E-Cigarette and Cannabis Social Media Posts and Adolescent Substance Use.
JAMA network open
JAMA Netw Open
8
6
10.1001/jamanetworkopen.2025.17611
eng
2,025
6
2
2,025
6
2
[IMPORTANCE] Adolescents are exposed to e-cigarette and cannabis content on social media. Understanding associations of these exposures with use and dual use of these products can guide regulations. [OBJECTIVE] To assess whether adolescent exposure to e-cigarette and/or cannabis content on social media, including posts...
null
3.546
154
Medicine
Medicine
2,024
40,553,371
Stepwise Administration of Bone-Targeted Lipid Nanoparticles Encapsulating Valproic Acid and TUDCA Facilitates In Vivo Direct Reprogramming for Osteoporosis Treatment.
Tissue engineering and regenerative medicine
Tissue Eng Regen Med
22
6
10.1007/s13770-025-00738-5
eng
2,025
8
null
2,025
6
24
[BACKGROUND] The ultimate goal of regenerative medicine is to restore damaged tissues to a healthy state in the body. Direct reprogramming, also referred to as transdifferentiation, holds significant therapeutic potential by converting abundant somatic cells, such as fibroblasts, into functionally distinct cell types f...
Bone-targeted lipid nanoparticles; Direct reprogramming; Mouse fibroblasts; Osteoporosis; Stepwise treatment
0.978
43
Biomedical Engineering; Medicine
Engineering; Medicine
2,024
40,552,316
Subgingival microbiota and genetic factors (A-2570G, A896G, and C1196T TLR4 polymorphisms) as periodontal disease determinants.
Frontiers in dental medicine
Front Dent Med
6
null
10.3389/fdmed.2025.1576429
eng
2,025
null
null
2,025
6
9
[BACKGROUND] Subgingival microbiota play an important role in maintaining oral health. Subgingival dysbiosis leads to the aggregation of highly pathogenic bacteria, and the host's genetics modulates the innate immune response. The interaction between these two factors plays an important role in the aggravation of perio...
TLR-4 polymorphism; dysbiosis; genetic factors; periodontal risk factor; periodontitis; subgingival microbiota
null
null
null
null
null
40,552,039
Association of triglyceride-glucose index with postoperative recovery-related factors in type II cesarean scar pregnancy treated by transvaginal surgery.
PeerJ
PeerJ
13
null
10.7717/peerj.19632
eng
2,025
null
null
2,025
6
20
[BACKGROUND] Type II cesarean scar pregnancy (CSP) is a rare and serious condition. The triglyceride-glucose index (TyG) may influence postoperative recovery-related factors (PRRF) as a marker of insulin resistance. This study investigates the relationship between TyG and PRRF in patients with type II CSP undergoing tr...
Transvaginal surgery; Triglyceride-glucose index; Type II cesarean scar pregnancy
0.625
124
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
40,551,384
Effect of glycemic control on tuberculosis treatment outcomes among patients with tuberculosis and diabetes mellitus: A systematic review and meta-analysis.
Tropical medicine international health : TM IH
Trop Med Int Health
30
8
10.1111/tmi.14140
eng
2,025
8
null
2,025
6
23
[INTRODUCTION] Tuberculosis (TB) and diabetes mellitus comorbidity can lead to poor TB treatment outcomes, particularly with uncontrolled blood glucose levels. Understanding the impact of glycemic control on TB treatment outcomes is essential. [OBJECTIVE] To synthesise evidence on the association between glycemic contr...
blood glucose; diabetes; glycaemic control; treatment failure; tuberculosis
null
null
null
null
null
40,551,315
Income-Level and Immigrant Status Are Associated With Discontinuation of Evidence-Based Secondary Prevention Therapies After Myocardial Infarction.
Journal of the American Heart Association
J Am Heart Assoc
14
13
10.1161/JAHA.124.041781
eng
2,025
7
null
2,025
6
23
[BACKGROUND] Mechanisms for worse prognosis after myocardial infarction in low socioeconomic status are unclear. We therefore investigated the association between socioeconomic status and discontinuation of evidence-based secondary prevention drug therapies. [METHODS] All patients with a first-ever myocardial infarctio...
cohort studies; medication adherence; myocardial infarction; secondary prevention; socioeconomic disparities in health
2.189
152
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,551,299
Is Plastic Surgery Resident Learning and Assessment Consistent? A Comparison of American Society of Plastic Surgery Educational Network Topics, In-Service Examinations, and Residency Core Curriculums.
Annals of plastic surgery
Ann Plast Surg
null
null
10.1097/SAP.0000000000004433
eng
2,025
6
23
2,025
6
23
[INTRODUCTION] The Plastic Surgery In-Service Examination (PSISE) objectively compares plastic and reconstructive surgery (PRS) residents' knowledge, while the ASPS' Education Network (EdNet) is a "gold standard," which programs use to design their curricula. This study aims to quantify the degree to which critical PRS...
ASPS; American Board of Plastic Surgery (ABPS); American Society of Plastic Surgeons (ASPS); EdNet; Education Network (EdNet); Plastic Surgery In-Service Examination (PSISE); Plastic and reconstructive surgery (PRS); curricula; education; in-service examination; learning; program directors; residency
0.598
112
Surgery
Medicine
2,024
40,551,276
An ultrasensitive and specific CRISPR-Cas13a-mediated point-of-care assay for monkeypox detection and PCR-based clade detection.
Infectious diseases of poverty
Infect Dis Poverty
14
1
10.1186/s40249-025-01325-5
eng
2,025
6
23
2,025
6
23
[BACKGROUND] The rapid increase in the number of monkeypox cases poses a considerable threat to the international community, necessitating sensitive, fast, and available diagnostic methods. Therefore, the objective of this study was to develop a rapid, sensitive and simple method with high clinical applicability. [METH...
CRISPR-Cas13a system; Lateral flow strip; MPXV clade detection; Monkeypox; Point-of-care assay
1.592
67
Infectious Diseases; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
40,551,176
Elevated drain fluid calprotectin as a predictor of early anastomotic leakage in colorectal surgery.
World journal of surgical oncology
World J Surg Oncol
23
1
10.1186/s12957-025-03899-8
eng
2,025
6
23
2,025
6
23
[BACKGROUND] Anastomotic leakage (AL) is a major cause of postoperative mortality following colorectal cancer surgery. This prospective investigation sought to establish the diagnostic utility of perioperative drain fluid calprotectin quantification in anticipating anastomotic complications following colorectal resecti...
Anastomotic leakage; Calprotectin; Colorectal cancer; Drain fluid; Surgery
0.782
82
Surgery; Oncology
Medicine
2,024
40,551,154
Enhancing retention and quality of tissue stromal vascular fraction graft with globo H ceramide.
Stem cell research therapy
Stem Cell Res Ther
16
1
10.1186/s13287-025-04395-2
eng
2,025
6
23
2,025
6
23
[BACKGROUND] Fat grafting has been extensively used in plastic surgery practice, yet unstable retention in the recipient site remains a significant clinical challenge. The limited tolerance of injected adipose tissue to ischemia has prompted strategies aiming at timely enhancing the vascularity of the grafted fat. Vari...
AD-MSC; AV shunt; Fat grafting; GHCer; Globo H ceramide; Tissue stromal vascular fraction; tSVF
null
null
null
null
null
40,551,149
Consumptive hypothyroidism complicating infantile hepatic hemangioma successfully treated with propranolol: a case report and literature review.
Italian journal of pediatrics
Ital J Pediatr
51
1
10.1186/s13052-025-02020-9
eng
2,025
6
23
2,025
6
23
[BACKGROUND] Consumptive hypothyroidism (CH) is a rare paraneoplastic syndrome, caused by the overexpression in vascular tumors of type 3 deiodinase (D3), converting thyroid hormones into inactive metabolites. [CASE PRESENTATION] We report the case of a 2-months-old male infant with diffuse infantile hepatic hemangioma...
Case report; Consumptive hypothyroidism; Infantile hepatic hemangioma; Propranolol; Thyroid hormones
0.836
65
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,551,077
Impact of self-rated health status on sleep disturbance among elderly diabetics: finding from the indonesian family life survey.
Sleep breathing = Schlaf Atmung
Sleep Breath
29
4
10.1007/s11325-025-03390-4
eng
2,025
6
23
2,025
6
23
[OBJECTIVE] Insufficient sleep quality is common among elderly adults with diabetes and can exacerbate existing health issues. Psychological factors, particularly self-assessed health status, play a key role in influencing sleep quality. This study aimed to examine the relationship between self-rated health status and ...
Elderly diabetes; Elderly psychology; Health education needs; Self-rated health status; Sleep disturbance
null
null
null
null
null
40,550,585
Lifelong experience of modified osteo-odonto-keratoprosthesis implantation over 50 years.
The British journal of ophthalmology
Br J Ophthalmol
null
null
10.1136/bjo-2025-327222
eng
2,025
6
23
2,025
6
23
[AIMS] The osteo-odonto-keratoprosthesis (OOKP) is a biological implant indicated for the treatment of eyes affected by corneal blindness, not amenable for keratoplasty. The purpose of the study is to report the long-term outcomes of patients undergone Falcinelli's modified OOKP (MOOKP). [METHODS] In this retrospective...
Cornea; Ocular surface; Prosthesis; Trauma
1.806
185
Cellular and Molecular Neuroscience; Ophthalmology; Sensory Systems
Medicine; Neuroscience
2,024
40,550,421
Non-linear early rapid hippocampal atrophy and associated microstructural injury in patients with nasopharyngeal carcinoma after radiotherapy: Implications for hippocampal protection.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Radiother Oncol
209
null
10.1016/j.radonc.2025.110997
eng
2,025
8
null
2,025
6
21
[BACKGROUND] Radiation-induced hippocampal atrophy is a key contributor to neurological dysfunction in patients with nasopharyngeal carcinoma (NPCs) after radiotherapy (RT); however, its dynamic pattern and underlying microstructural injury characteristics are unclear. [METHODS] In this prospective study, we longitudin...
Hippocampal atrophy; Microstructural injury; Nasopharyngeal carcinoma; Normal tissue complication probability model; Radiotherapy
1.738
189
Hematology; Oncology; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,550,374
Preoperative Weight Loss Among Morbidly Obese Patients Undergoing Total Knee Arthroplasty: It May Not Affect Outcomes.
The Journal of arthroplasty
J Arthroplasty
null
null
10.1016/j.arth.2025.06.061
eng
2,025
6
21
2,025
6
21
[BACKGROUND] The increasing obesity rate among total knee arthroplasty (TKA) patients presents a growing issue regarding surgical decision-making. Given the association between morbid obesity (MO, body mass index [BMI] ≥ 40) and postoperative complications, as well as the technical and physical challenges of performing...
morbid obesity; patient-reported outcomes; preoperative weight loss; total knee arthroplasty; weight loss guidelines; weight loss predictors
1.951
171
Orthopedics and Sports Medicine
Medicine
2,024
40,550,362
The Epidemiology of Sports-Related Orbital Fractures in the United States.
Ophthalmology
Ophthalmology
null
null
10.1016/j.ophtha.2025.06.016
eng
2,025
6
21
2,025
6
21
[PURPOSE] To characterize the epidemiologic features of sports-related orbital fractures in the United States, including incidence, demographic patterns, mechanisms of injury, and associated ocular injuries. [DESIGN] Retrospective cohort study. [PARTICIPANTS] Patients with sports-related facial fractures recorded in th...
Epidemiology; NEISS; Orbital fracture
4.552
297
Ophthalmology
Medicine
2,024
40,550,145
COVID-19 Vaccine Uptake, Sources of Information and Side Effects Reported by Pregnant Women in Western Australia: Cross-Sectional Cohort Survey.
JMIR pediatrics and parenting
JMIR Pediatr Parent
8
null
10.2196/66645
eng
2,025
6
23
2,025
6
23
[BACKGROUND] Pregnant women are a priority group for COVID-19 vaccination due to their vulnerability as a high-risk cohort. However, the currentCOVID-19 vaccine uptake rate for COVID-19 vaccination among pregnant women in Western Australia remains largely unknown. [OBJECTIVE] This study aimed to explore pregnant women'...
Australia; COVID-19; COVID-19 vaccination; maternity; pregnancy; pregnant; public health; side effects; uptake; vaccine uptake
0.775
22
Pediatrics, Perinatology and Child Health; Biomedical Engineering; Health Informatics
Engineering; Medicine
2,024
40,549,768
Global, regional, and national burden of cataract: A comprehensive analysis and projections from 1990 to 2021.
PloS one
PLoS One
20
6
10.1371/journal.pone.0326263
eng
2,025
null
null
2,025
6
23
[OBJECTIVE] Cataract is the most prevalent cause of blindness. Surgery remains the only effective and widely accepted treatment; early diagnosis and intervention can significantly prevent blindness. Hence,Understanding the current epidemiological status of cataract is crucial for formulating better healthcare policies ...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
40,549,427
AI in Medical Questionnaires: Scoping Review.
Journal of medical Internet research
J Med Internet Res
27
null
10.2196/72398
eng
2,025
6
23
2,025
6
23
[UNLABELLED] This systematic review aimed to explore the current applications, potential benefits, and issues of artificial intelligence (AI) in medical questionnaires, focusing on its role in 3 main functions: assessment, development, and prediction. The global mental health burden remains severe. The World Health Org...
AI; artificial intelligence; diagnostic accuracy; medical questionnaires; questionnaire development; questionnaire-based prediction
1.992
214
Health Informatics
Medicine
2,024
40,549,148
Effectiveness of, access to and need for electroconvulsive therapy in forensic psychiatric hospitals: a survey in Germany and Switzerland.
European archives of psychiatry and clinical neuroscience
Eur Arch Psychiatry Clin Neurosci
null
null
10.1007/s00406-025-02044-6
eng
2,025
6
23
2,025
6
23
[OBJECTIVE] Patients with treatment resistant schizophrenia (TRS) may benefit from electroconvulsive therapy (ECT). Although TRS is a frequent problem in forensic hospitals, ECT is rarely used in this setting. This study investigates the availability and implementation of ECT in forensic hospitals in Germany and Switze...
Capacity to consent; Electroconvulsive therapy (ECT); Forensic psychiatry; Questionnaire; Treatment-resistance
null
null
null
null
null