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40,548,679
Efficacy of additional ExTRa Mapping-guided substrate ablation beyond pulmonary vein isolation in persistent atrial fibrillation: The ROTATE trial.
Journal of cardiovascular electrophysiology
J Cardiovasc Electrophysiol
36
8
10.1111/jce.16772
eng
2,025
8
null
2,025
6
23
[INTRODUCTION] There are currently no established effective additional substrate ablation strategies beyond pulmonary vein isolation (PVI) for persistent atrial fibrillation (AF). [OBJECTIVE] This randomized clinical trial evaluated the efficacy of a novel substrate ablation technique using the ExTRa Mapping system, wh...
ExTRa mapping; atrial fibrillation; atrial fibrillation driver; catheter ablation; persistent atrial fibrillation
1.187
154
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,024
40,548,529
Pulsatile Normothermic Perfusion With Cardiopulmonary Bypass for Thoracic Organ Recovery in Donation After Uncontrolled Circulatory Death: A Feasible Strategy for Expanding the Donor Pool.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
Exp Clin Transplant
23
5
10.6002/ect.2025.0089
eng
2,025
5
null
null
null
null
[OBJECTIVES] Donation after circulatory death offers a promising solution to expand the thoracic organ donor pool, yet its application remains limited because of warm ischemia and technical barriers, especially in uncontrolled donation after circulatory death. We aimed to evaluate a pulsatile normothermic car-diopulmon...
null
0.263
37
Transplantation
Medicine
2,024
40,548,503
Evaluating the Role of an Objective Lower Gastrointestinal Assessment as Part of ERAS Pathway Following hRAMIE.
Journal of surgical oncology
J Surg Oncol
null
null
10.1002/jso.70018
eng
2,025
6
23
2,025
6
23
[BACKGROUND] Postoperative esophagram is commonly employed following hybrid robotic-assisted minimally invasive esophagectomy (hRAMIE) to assess proper gastric conduit emptying. However, we hypothesize that the passage of enteric contents through the entire gastrointestinal tract is equally critical for patient recover...
enhanced recovery after surgery; esophagectomy; gastrointestinal assessment; outcomes
0.741
136
Surgery; Medicine; Oncology
Medicine
2,024
40,548,357
Abnormalities of Hippocampal Subfields in Individuals With Acute Carbon Monoxide Poisoning.
CNS neuroscience therapeutics
CNS Neurosci Ther
31
6
10.1111/cns.70482
eng
2,025
6
null
null
null
null
[OBJECTIVE] To investigate alterations in hippocampal subfields in patients with acute carbon monoxide poisoning (ACMP) and explore their relationship with neurocognitive function. [MATERIALS AND METHODS] Forty-seven ACMP patients and 29 age- and sex-matched healthy controls (HCs) were recruited. All ACMP patients unde...
CO; carbon monoxide poisoning; delayed encephalopathy; hippocampus; subfield
null
null
null
null
null
40,548,309
Current Rates and Trends of Venous Thromboembolism After Total Hip and Knee Arthroplasty: An Updated Analysis Utilizing the NSQIP Database.
Arthroplasty today
Arthroplast Today
33
null
10.1016/j.artd.2025.101737
eng
2,025
6
null
2,025
6
9
[BACKGROUND] Total hip arthroplasty (THA) and total knee arthroplasty (TKA) procedure volumes are increasing. Venous thromboembolism (VTE) remains a significant complication, with incidence rates between 0.45% and 5.30%. Enhanced rapid-recovery pathways and chemoprophylaxis evolution may correlate with decreased VTE ev...
Complications; Deep vein thrombosis; Pulmonary embolism; Total hip arthroplasty; Total knee arthroplasty; Venous thromboembolism
0.918
32
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
40,548,123
The Impact of Social Deprivation on Phalangeal Fracture Operative Treatment Outcomes.
Journal of hand surgery global online
J Hand Surg Glob Online
7
4
10.1016/j.jhsg.2025.100765
eng
2,025
7
null
2,025
6
5
[PURPOSE] The purpose of this study was to evaluate the relationship between social determinants of health and outcomes following phalangeal fracture surgery using the Area Deprivation Index. [METHODS] A retrospective chart review was performed on patients ≥18 years old who underwent surgical fixation of a proximal, mi...
Fracture; Hand; Phalangeal; Phalanx; Social
0.474
11
Rehabilitation; Surgery; Orthopedics and Sports Medicine
Medicine
2,024
40,547,953
Enhancing clinical practice through action research: fostering a person-centred culture in healthcare.
Frontiers in health services
Front Health Serv
5
null
10.3389/frhs.2025.1583478
eng
2,025
null
null
2,025
6
6
[INTRODUCTION] Despite the growing recognition of person-centred practice in political declarations, strategic visions, and healthcare policies, a significant gap remains between the theoretical underpinnings of person-centred practice and its practical application in clinical settings. To bridge this gap, two departme...
action reseach; implementation; participatory; person-centred care; person-centred culture
0.956
13
Medicine
Medicine
2,024
40,547,923
Factors influencing pathological complete response following neoadjuvant chemoimmunotherapy in locally advanced microsatellite stable colorectal cancer: a retrospective analysis.
Frontiers in medicine
Front Med (Lausanne)
12
null
10.3389/fmed.2025.1587684
eng
2,025
null
null
2,025
6
6
[OBJECTIVE] The purpose of this study is to identify and analyze the factors associated with achieving pathological complete response (pCR) in patients with locally advanced microsatellite stable (MSS) or proficient mismatch repair (pMMR) colorectal cancer who underwent neoadjuvant chemoimmunotherapy. [METHODS] A retro...
clinical factors; colorectal cancer; microsatellite stable; neoadjuvant chemoimmunotherapy; pathological complete response; proficient mismatch repair
0.962
102
Medicine
Medicine
2,024
40,547,814
Outcomes of radial-sided wrist hemiarthroplasty: A systematic review.
Journal of orthopaedics
J Orthop
69
null
10.1016/j.jor.2025.05.039
eng
2,025
11
null
2,025
5
22
[PURPOSE] Wrist hemiarthroplasty (WHA) has gained popularity as a motion-sparing alternative to either total wrist arthroplasty or wrist arthrodesis for a variety of pathologies, yet limited data currently supports its use. This systematic review was performed to evaluate the clinical outcomes and complications followi...
Arthroplasty; Functional outcomes; Hemiarthroplasty; Resurfacing; Wrist
0.67
41
Orthopedics and Sports Medicine
Medicine
2,024
40,547,335
Risk Prediction of Cerebrovascular Ischemic Events Following Cervical Artery Dissections Using High-Intensity Transient Signals: A Systematic Review, Meta-Analysis and a single center experience.
Stroke (Hoboken, N.J.)
Stroke Vasc Interv Neurol
5
3
10.1161/SVIN.124.001704
eng
2,025
5
null
2,025
3
8
[BACKGROUND] Predicting and managing spontaneous Cervical Artery Dissections (CeAD) is challenging due to the absence of tools for early identification of high-risk individuals. This study seeks to gather evidence on the predictive value of high-intensity transient signals (HITS) detected by Transcranial Doppler for re...
Transcranial Doppler; dissection; high-intensity transient signals; ischemic events; microembolic signals; stroke
2.659
370
Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience
Medicine; Neuroscience; Nursing
2,024
40,547,267
Patient Preferences and Perceptions Regarding Their Gender-Affirming Plastic Surgeon.
Transgender health
Transgend Health
10
3
10.1089/trgh.2023.0084
eng
2,025
6
null
2,025
6
5
[PURPOSE] We sought to better understand the preferences of transgender and gender diverse (TGD) patients regarding the professional qualities and gender identity of their gender-affirming plastic surgeon, as well as whether they preferred a surgeon who identifies as a member of the lesbian, gay, bisexual, transgender,...
LGBT surgeons; gender affirming surgery; identity concordance; patient preferences; plastic and reconstructive surgery
0.903
45
Gender Studies; Medicine
Medicine; Social Sciences
2,024
40,547,027
The N-6 methyladenosine dynamics in STEMI and the effect of IL-6 inhibition - a hypothesis generating sub-study of the ASSAIL-MI trial.
Frontiers in immunology
Front Immunol
16
null
10.3389/fimmu.2025.1532325
eng
2,025
null
null
2,025
6
6
[BACKGROUND] Epitranscriptomics, with m[6]A as the most prevalent in mammals, is a novel treatment target for inflammatory diseases, including cardiovascular diseases. However, little is known about m[6]A RNA-regulation during myocardial infarction (MI). [METHODS] In this explorative sub-study of the ASSAIL-MI trial, w...
N6-methyladenosine (m6A); RNA methylation; STEMI; epitranscriptome; inflammation; tocilizumab
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,546,656
Exploring the Therapeutic Potential of FSGTC for Osteoarthritis: A Comprehensive Study Combining Nested Case Analysis, Network Pharmacology, and Experimental Validation.
Drug design, development and therapy
Drug Des Devel Ther
19
null
10.2147/DDDT.S517935
eng
2,025
null
null
2,025
6
17
[OBJECTIVE] This research aims to clarify the clinical efficacy and potential mechanisms of Fengshi Gutong capsule (FSGTC) in improving inflammatory response and hypercoagulability in osteoarthritis (OA) patients, and to evaluate the safety of FSGTC. [METHODS] A nested case-control study and association rule analysis w...
PI3K/AKT pathway; fengshi gutong capsule; hypercoagulable state; inflammatory response; osteoarthritis
1.19
108
Drug Discovery; Pharmaceutical Science; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
40,546,452
Exploring Health-Related Quality of Life and Correlates Among Patients with Type 2 Diabetes Mellitus Attending Primary Health Centers in Aljouf Province, Saudi Arabia: A Multi-Site Cross-Sectional Study.
Risk management and healthcare policy
Risk Manag Healthc Policy
18
null
10.2147/RMHP.S514414
eng
2,025
null
null
2,025
6
18
[PURPOSE] Type 2 diabetes mellitus (T2DM) impacts various elements of health-related quality of life (HRQoL). However, research on the HRQoL of T2DM patients in primary healthcare settings in Saudi Arabia is limited. Therefore, we aimed to determine the HRQoL and associated factors among patients with T2DM to plan poli...
SF-20; T2DM patients; diabetes mellitus; pain management; primary healthcare; quality of life
0.728
53
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,024
40,546,324
Resting-State Network Dynamics in Asthma: Interplay Between Depressive Symptoms and Airway Inflammation.
Biological psychiatry global open science
Biol Psychiatry Glob Open Sci
5
5
10.1016/j.bpsgos.2025.100527
eng
2,025
9
null
2,025
5
8
[BACKGROUND] Asthma and depression frequently co-occur, potentially worsening each other's symptoms. The salience network (SN) may play a key role in this link, but the roles of the default mode network (DMN) and frontoparietal network (FPN), as outlined in the triple network theory, remain unclear in the asthma-depres...
Asthma; Depression; Graph theory; Inflammation; Triple network theory; fMRI
null
null
null
null
null
40,546,104
Neural dysfunction, inflammatory disorder, and metabolic interference feature in amantadine-related adverse drug events: a perspective from FAERS and network toxicology.
Expert opinion on drug safety
Expert Opin Drug Saf
null
null
10.1080/14740338.2025.2524400
eng
2,025
6
26
2,025
6
26
[BACKGROUND] Adverse drug events (ADEs) related to amantadine gradually increase as the drug is broadly acknowledged for remission of Parkinson's disease or Parkinsonism. The ADEs vary according to the affected organs and the potential mechanisms remain elusive. [METHODS] We mined data from the FAERS Database and emplo...
Amantadine; FAERS; Mechanism; Toxicology; adverse drug event
0.785
96
Medicine; Pharmacology
Medicine
2,024
40,545,829
The Experiences of Critical Care Nurses Implementing Point-Of-Care Ultrasound: A Qualitative Study.
Nursing in critical care
Nurs Crit Care
30
4
10.1111/nicc.70104
eng
2,025
7
null
null
null
null
[BACKGROUND] Point-of-care ultrasound (POCUS) has emerged as a transformative tool in critical care, enabling rapid bedside assessment of haemodynamic status, organ dysfunction and procedural guidance. While its integration into physician practice is well established, the expansion of POCUS utilisation by nurses remain...
critical care; intensive care unit (ICU) nurses; qualitative research
0.948
56
Critical Care Nursing
Nursing
2,024
40,545,752
Switching biologic agent in patients with psoriasis: a systematic review and meta-analysis.
The Journal of dermatological treatment
J Dermatolog Treat
36
1
10.1080/09546634.2025.2521082
eng
2,025
12
null
2,025
6
22
[BACKGROUND] Multiple biologics are available for psoriasis treatment, but switching treatments is often necessary at some point. The choice between intraclass or interclass biologic switching has not been extensively investigated. [METHODS] Two independent authors searched the databases PubMed and EMBASE for studies r...
Biologics; failure; interclass switch; intraclass switch
1.067
69
Dermatology
Medicine
2,024
40,545,524
MicroRNA- 103 as a novel potential biomarker of poor prognosis and durg resistance in solid tumours.
Discover oncology
Discov Oncol
16
1
10.1007/s12672-025-02963-9
eng
2,025
6
22
2,025
6
22
[BACKGROUD] Multiple studies have reported that microRNA-103 is unregulated in a variety of tumours, involved in tumorigenesis, and associated with tumour prognosis, so a systematic review and meta-analysis were performed to determine the relationship between microRNA-103 and the prognosis of solid tumours. [METHODS] T...
Overall survival; Prognostic; Solid tumour; microRNA-103
0.88
47
Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
40,545,494
Association between blood pressure and cardiovascular events and mortality in patients on peritoneal dialysis: a systematic review and meta-analysis of observational studies.
Clinical and experimental nephrology
Clin Exp Nephrol
null
null
10.1007/s10157-025-02719-3
eng
2,025
6
22
2,025
6
22
[BACKGROUND] The association between blood pressure (BP) and adverse outcomes in peritoneal dialysis (PD) remains uncertain. This study aims to address this knowledge gap. [MATERIALS AND METHODS] We systematically searched five databases (1964-2025) for observational studies assessing associations between BP and mortal...
Blood pressure; Meta-analysis; Mortality; Peritoneal dialysis; Systematic review
0.661
67
Nephrology; Physiology; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,545,378
Development of Radiomics-Based Risk Prediction Models for Stages of Hashimoto's Thyroiditis Using Ultrasound, Clinical, and Laboratory Factors.
Ultrasound in medicine biology
Ultrasound Med Biol
51
9
10.1016/j.ultrasmedbio.2025.05.025
eng
2,025
9
null
2,025
6
22
[OBJECTIVES] To develop a radiomics risk-predictive model for differentiating the different stages of Hashimoto's thyroiditis (HT). [METHODS] Data from patients with HT who underwent definitive surgical pathology between January 2018 and December 2023 were retrospectively collected and categorized into early HT (HT pat...
Artificial intelligence; Clinical indicators; Early diagnosis; Hashimoto's thyroiditis; Machine learning; Radiomics; Risk prediction; Ultrasound imaging
null
null
null
null
null
40,545,308
Associations of educational level with ECG-derived cardiovascular ageing in a population-based cohort: a mediation analysis from the Tromsø Study.
BMJ open
BMJ Open
15
6
10.1136/bmjopen-2024-088671
eng
2,025
6
22
2,025
6
22
[OBJECTIVE] To assess the association between educational level and cardiovascular age acceleration metric derived from ECG, and to determine whether this association is mediated by established cardiovascular disease (CVD) risk factors. [DESIGN] Prospective population-based cohort study (the Tromsø Study). [SETTING] Ge...
Aging; Cardiac Epidemiology; EPIDEMIOLOGY; PUBLIC HEALTH
1.016
176
Medicine
Medicine
2,024
40,545,258
Risk Factors and Multiple Interaction Effects for Hyperammonemia in Patients Receiving Valproic Acid.
Fundamental clinical pharmacology
Fundam Clin Pharmacol
39
4
10.1111/fcp.70030
eng
2,025
8
null
null
null
null
[BACKGROUND] Valproic acid (VPA) use is associated with an increased risk of hyperammonemia (HA); however, the specific interactions between HA risk factors in VPA-treated patients remain unclear. [OBJECTIVES] This study aimed to identify and assess the effects of multiple interactions between different risk factors af...
hyperammonemia; multiple interactions; valproic acid
null
null
null
null
null
40,545,207
A mobile relational agent to enhance atrial fibrillation self-care: Primary and secondary outcomes of a randomized controlled trial.
American heart journal
Am Heart J
290
null
10.1016/j.ahj.2025.06.009
eng
2,025
6
20
2,025
6
20
[BACKGROUND] Atrial fibrillation (AF) requires long-term adherence to oral anticoagulation and self-care. [METHODS] We conducted a randomized controlled trial of a smartphone-based relational agent and heart rhythm monitor with the primary outcome of anticoagulation adherence and secondary outcomes of quality of life (...
Atrial fibrillation; Proportion of Days Covered; anticoagulation; human-computer interaction; medication adherence; self-care
2.039
211
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,545,163
Clinical course and features of thyroid oncocytic (Hurthle cell) cancer: Comparison with thyroid follicular cancer.
Revista espanola de medicina nuclear e imagen molecular..
Rev Esp Med Nucl Imagen Mol (Engl Ed)
null
null
10.1016/j.remnie.2025.500158
eng
2,025
6
20
2,025
6
20
[INTRODUCTION AND OBJECTIVES] Although, oncocytic (Hurthle cell) carcinoma (OTC) resembles to follicular thyroid carcinoma (FTC), they are different tumors derived from thyroid follicular cells. OTC comprises 3-5% of all differentiated thyroid carcinomas and has more aggressive behaviour than FTC. Clinicians discuss ab...
Carcinoma folicular de tiroides; Follicular thyroid cancer; Oncocytic thyroid cancer; Predictor variable; Recurrence; Recurrencia
0.216
25
Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,544,987
Trends and institutional patterns of extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest in Korea: a nationwide analysis, 2016-2023.
Resuscitation
Resuscitation
null
null
10.1016/j.resuscitation.2025.110692
eng
2,025
6
20
2,025
6
20
[BACKGROUND] While the clinical effectiveness of extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) has gained increasing attention, its real-world utilization, patient selection, and system-level implementation remain incompletely understood. [METHODS] We conducted a descript...
Cardiopulmonary Resuscitation; Emergency Departments; Extracorporeal Membrane Oxygenation; Out-of-Hospital Cardiac Arrest; Spatial Analysis
2.032
162
Cardiology and Cardiovascular Medicine; Emergency Medicine; Emergency Nursing
Medicine; Nursing
2,024
40,544,277
Integrated peripheral blood multi-omics profiling identifies immune signatures predictive of neoadjuvant PD-1 blockade efficacy in head and neck squamous cell carcinoma.
Journal of translational medicine
J Transl Med
23
1
10.1186/s12967-025-06770-2
eng
2,025
6
21
2,025
6
21
[BACKGROUND] Neoadjuvant PD-1 inhibitor therapy has shown promise in locally advanced head and neck squamous cell carcinoma (HNSCC), but only a subset of patients achieves major pathological responses. Liquid biopsy, the analysis of tumor-derived biomarkers in readily accessible bodily fluids (primarily blood), offers ...
Head and neck squamous cell carcinoma; Liquid biopsy; Multi-omics research; Neoadjuvant therapy; PD-1 inhibitor
1.997
153
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,544,080
Clinical impact of COVID-19 respiratory infection 15 months after intensive care unit discharge.
Medicina intensiva
Med Intensiva (Engl Ed)
null
null
10.1016/j.medine.2025.502230
eng
2,025
6
20
2,025
6
20
[OBJECTIVES] To determine the prevalence of persistent COVID-19 symptoms in SARS-CoV-2 patients 15 months after ICU discharge,their impact on physical, psychological, and neurocognitive domains, and the burden on primary caregivers. [DESIGN] Descriptive, ambispective observational study. [SETTING] Intensive Care Unit f...
COVID persistente; COVID-19; Intensive Care Unit; Long COVID; Post-COVID syndrome; Post-Intensive Care Syndrome; Unidad de Cuidados Intensivos
0.353
41
Critical Care and Intensive Care Medicine
Medicine
2,024
40,543,901
Loss of apolipoprotein E contributes to inflammatory macrophage activation and ferroptosis in NSAID-exacerbated respiratory disease.
The Journal of allergy and clinical immunology
J Allergy Clin Immunol
null
null
10.1016/j.jaci.2025.06.010
eng
2,025
6
19
2,025
6
19
[BACKGROUND] Nonsteroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD) is characterized by chronic asthma, nasal polyposis, and intolerance of nonsteroidal anti-inflammatory drugs. We recently described aberrant macrophage activation and lipid metabolism in N-ERD; however, local drivers of nasal infla...
Macrophage; NSAID-exacerbated respiratory disease; apolipoprotein; ferroptosis; innate immunity; mucosal immunology
3.935
350
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,543,451
Exploration of pharmacological potentialities of Bauhinia acuminata L. fruits by in vitro and in vivo assays supported by computational analysis.
Journal of Ayurveda and integrative medicine
J Ayurveda Integr Med
16
4
10.1016/j.jaim.2025.101127
eng
2,025
null
null
2,025
6
20
[BACKGROUND] In Ayurveda, Bauhinia acuminata L. had been used to treat diabetes, skin diseases, and swelling. [OBJECTIVE] The study was designed to assess the antidiabetic, anti-inflammatory, and antibacterial potentialities of B. acuminata fruits ethanolic extract. Phytochemical characterization by HPLC analysis, pure...
ADMET analysis; Anti-inflammatory; Antibacterial; Antidiabetic; Bauhinia acuminata L.; Molecular docking analysis
0.373
42
Complementary and Alternative Medicine; Drug Discovery
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,543,178
Review of Radiotherapy Activity in Scotland, 2 Years Post COVID.
Clinical oncology (Royal College of Radiologists (Great Britain))
Clin Oncol (R Coll Radiol)
44
null
10.1016/j.clon.2025.103862
eng
2,025
8
null
2,025
5
9
[AIMS] Now that the world has returned to normal following the COVID-19 pandemic, there are concerns that the pandemic has had a negative, ongoing effect on cancer care. This study aims to investigate the impact of the COVID-19 pandemic on radiotherapy services in Scotland. [MATERIALS AND METHODS] Detailed quantitative...
COVID-19; SARS-CoV-2; Scotland; UK; pandemic; radiotherapy
0.965
94
Radiology, Nuclear Medicine and Imaging; Oncology
Medicine
2,024
40,542,929
Assessment of test-retest reproducibility by [[18]F]Bavarostat for PET imaging of HDAC6.
EJNMMI research
EJNMMI Res
15
1
10.1186/s13550-025-01268-w
eng
2,025
6
21
2,025
6
21
[BACKGROUND] Histone deacetylase 6 (HDAC6) is an enzyme pivotal for gene regulation, influencing cellular pathways through protein deacetylation. HDAC6 is a potential therapeutic target in diseases such as cancer and neurodegenerative disorders. Koole et al. investigated brain binding of [[18]F]Bavarostat, an HDAC6 inh...
Brain imaging; HDAC6; Human study; Positron emission tomography; Test-retest reproducibility
0.94
58
Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,542,909
Intraosseous route is associated with prolonged epinephrine-to-ROSC interval in out-of-hospital cardiac arrest.
Irish journal of medical science
Ir J Med Sci
null
null
10.1007/s11845-025-03979-4
eng
2,025
6
21
2,025
6
21
[BACKGROUND] Prolonged resuscitation is associated with poor patient outcomes. While the importance of bystander CPR and early defibrillation is well-known, the role of other components affecting resuscitation duration is less well-established. We postulated that first-dose intraosseous (IO) epinephrine would prolong t...
Cardiac arrest; Cardiopulmonary resuscitation; Emergency medical services; Epinephrine; Paramedic
0.543
46
Medicine
Medicine
2,024
40,542,744
Incidence of Methemoglobinemia in Cardiothoracic Surgery ICU Patients on Inhaled Nitric Oxide.
The Annals of pharmacotherapy
Ann Pharmacother
null
null
10.1177/10600280251340182
eng
2,025
6
21
2,025
6
21
[BACKGROUND] Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator utilized for the treatment of right ventricular dysfunction in the cardiac surgery patient population, which carries a risk of developing methemoglobinemia. The actual frequency of methemoglobinemia is not well defined. [OBJECTIVE] The purpose...
cardiothoracic surgery; critical care; intensive care unit; methemoglobin; methemoglobinemia; nitric oxide
0.788
125
Medicine; Pharmacology
Medicine
2,024
40,542,146
A survey of pathogenic involvement in non-communicable human diseases.
Communications medicine
Commun Med (Lond)
5
1
10.1038/s43856-025-00956-x
eng
2,025
6
20
2,025
6
20
[BACKGROUND] Many relationships between pathogens and human disease are well-established. However, only a small fraction involve diseases considered non-communicable (NCDs). In this study, we sought to leverage the vast amount of newly available electronic health record data to identify potentially novel pathogen-NCD a...
null
2.098
28
Assessment and Diagnosis; Epidemiology; Internal Medicine; Medicine; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,024
40,541,834
Association between folate intake and suicidal ideation: NHANES 2005-2018 and Mendelian randomization.
Journal of affective disorders
J Affect Disord
389
null
10.1016/j.jad.2025.119730
eng
2,025
11
15
2,025
6
18
[BACKGROUND] Previous findings indicated that there was an association between folate intake and suicidal behaviors. Nevertheless, whether folate intake influences suicidal ideation remains inconclusive. Consequently, this research focuses on investigating the link between folate intake and suicidal ideation. [METHODS]...
Cross-sectional study; Folate intake; Mendelian randomization; NHANES; Suicidal ideation
2.121
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
40,541,818
IL-10 alleviates ulcerative colitis by regulating mitochondrial function through reducing ISG15 expression.
Cellular signalling
Cell Signal
134
null
10.1016/j.cellsig.2025.111932
eng
2,025
10
null
2,025
6
18
[BACKGROUND] Interleukin-10 (IL-10), an anti-inflammatory cytokine, has shown therapeutic effect on autoimmune diseases, yet its effects on UC remain unclear. This study aims to investigate whether the administration of IL-10 can suppress disease flares in ulcerative colitis (UC). [METHODS] A UC model was established i...
Autophagy; IL-10; ISG15; Intestinal barrier; Mitochondrial function; Ulcerative colitis
1.239
172
Cell Biology
Biochemistry, Genetics and Molecular Biology
2,024
40,541,728
Comparative study and relevant exploration on methods for establishing unfractionated heparin therapeutic range (HTR) based on APTT.
Clinica chimica acta; international journal of clinical chemistry
Clin Chim Acta
577
null
10.1016/j.cca.2025.120435
eng
2,025
9
1
2,025
6
18
[BACKGROUND] Building heparin therapeutic range (HTR) to monitoring unfractionated heparin (UFH) is important, while the two methods for establishing HTR exhibit discrepancies and yield different HTR results. The manifestations and underlying factors contributing to these discrepancies remain areas of uncertainty. [MET...
Anti-Xa activity; Coagulation factor; Method; Monitoring; Unfractionated Heparin
null
null
null
null
null
40,541,551
Usefulness of [[18]F]FAPI-04 and [[18]F]FDG PET/CT for the Detection of Peritoneal Carcinomatosis: A Comparative Study.
Academic radiology
Acad Radiol
null
null
10.1016/j.acra.2025.05.067
eng
2,025
6
19
2,025
6
19
[RATIONALE AND OBJECTIVES] In this study, we aimed to compared the performance of [[18]F]FAPI-04 and [[18]F]fluorodeoxyglucose (FDG) positron emission tomography/computer tomography (PET/CT) in the evaluation of peritoneal carcinomatosis. [MATERIALS AND METHODS] 71 patients with suspected peritoneal malignancies were e...
PET/CT; Peritoneal cancer index; Peritoneal carcinomatosis; [(18)F]FAPI-04; [(18)F]FDG
0.992
113
Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,541,432
Relationship between resilience and social trust in nursing homes in Guangzhou, China: a cross-sectional study.
BMJ open
BMJ Open
15
6
10.1136/bmjopen-2024-094601
eng
2,025
6
20
2,025
6
20
[OBJECTIVES] To identify latent resilience profiles among older adults residing in nursing homes and to examine the mediating role of perceived social support in the relationship between resilience and social trust. [DESIGN] A cross-sectional survey conducted between January and May 2023. [SETTING] Three nursing homes ...
Aging; Nursing Care; Patient-Centered Care; Social Cognition; Social Support
1.016
176
Medicine
Medicine
2,024
40,540,211
The association of peripheral blood METTL3 mRNA expression levels with prediabetes and type 2 diabetes mellitus: the Henan rural cohort study.
Acta diabetologica
Acta Diabetol
null
null
10.1007/s00592-025-02542-y
eng
2,025
6
20
2,025
6
20
[AIM] We aimed to investigate the association of peripheral blood METTL3 (Methyltransferase Like 3) mRNA expression levels with impaired fasting glucose (IFG) and type 2 diabetes mellitus (T2DM). [MATERIALS AND METHODS] A case-control study including 1501 participants from the Henan Rural Cohort study was performed. Pe...
METTL3 mRNA expression levels; Case-control study; Henan rural cohort study; Impaired fasting glucose; Type 2 diabetes mellitus
1.07
90
Medicine; Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,539,346
Formulation, Optimization and Design of Capecitabine Nanosuspension to Enhance the Anti-Gastric Cancer Efficacy using Box-Behnken Quality-based Design Study.
Current drug discovery technologies
Curr Drug Discov Technol
null
null
10.2174/0115701638371974250606041312
eng
2,025
6
13
2,025
6
13
[BACKGROUND] Capecitabine is an anticancer antimetabolite of fluorouracil that inhibits cell proliferation and impairs DNA repair in cancer cells. It is given specifically to treat metastatic breast, gastric and colorectal cancers. [OBJECTIVE] To design, formulate, optimize and evaluate Capecitabine Nanosuspension usin...
Gastric cancer; QbD; and bioavailability.; box-behnken; capecitabine; nanosuspension
null
null
null
null
null
40,539,201
Impact of visceral fat distribution on postoperative complications in high-aged patients undergoing gastric cancer surgery: A cross-sectional study.
World journal of gastroenterology
World J Gastroenterol
31
22
10.3748/wjg.v31.i22.105201
eng
2,025
6
14
null
null
null
[BACKGROUND] The annual incidence of gastric cancer in elderly patients is increasing. Despite the continuous progress in treatment methods, the prognosis of elderly patients remains poor, and postoperative complications are frequent. Obesity is believed to be associated with the risk of gastric cancer and postoperativ...
Complications; Cross-sectional study; Gastric cancer; Risk factor; Visceral fat distribution
null
null
null
null
null
40,538,977
Concurrent Capillary Hemangioma of Optic Disc and Pituitary Gland Cyst: A Multimodal Imaging Approach and Review of Literature.
Case reports in oncology
Case Rep Oncol
18
1
10.1159/000544876
eng
2,025
null
null
2,025
5
30
[INTRODUCTION] Coexistence of optic disc hemangioma and pituitary gland cyst is a rare clinical scenario. Usually, a retinal capillary hemangioma or juxtapapillary hemangioma is associated with VHL syndrome. This case emphasizes the clinical presentation, diagnostic approach, and implications for patient care. [CASE PR...
Intraocular tumor; Optic nerve head hemangioma; Pituitary gland cyst
0.281
28
Oncology
Medicine
2,024
40,538,932
Prevalence of sub-optimal feeding practices and associated factors in very low birth weight infants admitted to the special care unit, Kawempe Hospital in Uganda.
Frontiers in pediatrics
Front Pediatr
13
null
10.3389/fped.2025.1558163
eng
2,025
null
null
2,025
6
5
[BACKGROUND] Over 60% of Very Low Birth Weight (VLBW) infants worldwide are born in Sub-Saharan Africa and South Asia. VLBW infants are born nutritionally disadvantaged, as they are suddenly and prematurely moved from a nutrient-rich to a nutrient-deficient environment. Therefore, appropriate feeding during the early n...
Uganda; early weight change; growth velocity; special care; sub-optimal feeding; very low birth weight
0.738
83
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,538,679
Childhood Trauma in Spanish Women with Fibromyalgia and Depression.
Women's health reports (New Rochelle, N.Y.)
Womens Health Rep (New Rochelle)
6
1
10.1089/whr.2024.0118
eng
2,025
null
null
2,025
5
30
[INTRODUCTION] Childhood trauma (CT) is associated with chronic widespread pain and high rates of pain sensitization, which are typical of fibromyalgia (FM), and with FM itself. The present investigation was twofold: it analyzed the prevalence of single types and cumulative types of CT in a Spanish sample of women diag...
childhood maltreatment; chronic pain; cumulative trauma; depression Spanish sample
0.45
9
Advanced and Specialized Nursing; Maternity and Midwifery; Medicine; Obstetrics and Gynecology; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,024
40,538,657
Global trends and regional disparities in the burden of headache disorders, 1990-2021: a comprehensive analysis of the global burden of disease study.
Frontiers in neurology
Front Neurol
16
null
10.3389/fneur.2025.1575705
eng
2,025
null
null
2,025
6
5
[BACKGROUND] Headache disorders significantly impact health and functioning, yet studies on their global burden across all age groups are limited. This study utilizes data from the Global Burden of Disease (GBD) 2021 to investigate the global burden of headache disorders. [METHODS] This analysis draws on GBD 2021 data,...
decomposition analysis; estimated annual percentage change; global burden of disease; headache disorders; health inequality; socio-demographic index
0.993
118
Neurology; Neurology
Medicine; Neuroscience
2,024
40,538,623
Peripheral myelin protein 2 is underexpressed in early-onset colorectal cancer and inhibits metastasis.
Frontiers in molecular biosciences
Front Mol Biosci
12
null
10.3389/fmolb.2025.1610003
eng
2,025
null
null
2,025
6
5
[BACKGROUND] The occurrence and fatality rates of early-onset colorectal cancer (EOCRC) are increasing, with metastasis being one of the primary causes of the high mortality rate in EOCRC patients. Currently, there is a shortage of biomarkers for diagnosis and targets for treatment with optimal efficacy and reliability...
PMP2; early-onset colorectal cancer; machine learning; metastasis; weighted gene co-expression network analysis
1.243
85
Biochemistry; Biochemistry, Genetics and Molecular Biology; Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,024
40,538,590
Association between the dietary index for gut microbiota and cardiometabolic multimorbidity: systemic immune-inflammation index and systemic inflammatory response index.
Frontiers in nutrition
Front Nutr
12
null
10.3389/fnut.2025.1591799
eng
2,025
null
null
2,025
6
5
[OBJECTIVE] This study targets to investigate the connection between the possibility of Cardiometabolic Multimorbidity (CMM) and the Dietary Index for Gut Microbiota (DI-GM), paying special attention to the mediating roles of systemic inflammatory markers, specifically the Systemic Immune-Inflammation Index (SII) and t...
NHANES; cardiometabolic multimorbidity; dietary index for gut microbiota; systemic immune-inflammation index; systemic inflammatory response index
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
40,538,564
Assessment of Sleep Quality and Its Determinants Among Patients with Type 2 Diabetes Mellitus in Mogadishu, Somalia: A Cross-Sectional Study.
Diabetes, metabolic syndrome and obesity : targets and therapy
Diabetes Metab Syndr Obes
18
null
10.2147/DMSO.S533810
eng
2,025
null
null
2,025
6
15
[BACKGROUND] Type 2 diabetes mellitus (T2DM) is a growing global health crisis, affecting hundreds of millions worldwide. Poor sleep quality-often under-recognized-impairs glycemic control and accelerates diabetes-related complications. Despite its clinical relevance, data on sleep quality among T2DM patients in Somali...
Mogadishu; Somalia; determinants; sleep quality; type 2 diabetes mellitus
0.827
71
Internal Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,538,540
Curcumin and multiple health outcomes: critical umbrella review of intervention meta-analyses.
Frontiers in pharmacology
Front Pharmacol
16
null
10.3389/fphar.2025.1601204
eng
2,025
null
null
2,025
6
5
[OBJECTIVE] This review aimed to determine the therapeutic effects and safety of oral curcumin compared with other comparators for human health and wellbeing outcomes. [METHODS] PubMed, Embase, and Cochrane Library were searched from their inception to 18 June 2024. The Assessment of Multiple Systematic Reviews-2 check...
curcumin; evidence; health outcomes; meta-analysis; metabolic indicators; umbrella review
1.22
175
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,537,936
Prevalence of cardiac dysfunction in men with erectile dysfunction: the EDcard study.
BJU international
BJU Int
136
3
10.1111/bju.16824
eng
2,025
9
null
2,025
6
19
[OBJECTIVES] To assess the prevalence of myocardial impairment in men with erectile dysfunction (ED) as compared with the general population using conventional and two-dimensional speckle-tracking echocardiography. [SUBJECTS AND METHODS] In this cross-sectional study, men with ED underwent clinical, electrocardiographi...
cardiac disease; cardiac dysfunction; cardiovascular disease; echocardiography; erectile dysfunction; global longitudinal strain
1.588
174
Urology
Medicine
2,024
40,537,228
Barriers to informed consent in obstetric care during childbirth from practitioner's perspective: a qualitative study.
BMJ open
BMJ Open
15
6
10.1136/bmjopen-2025-101591
eng
2,025
6
19
2,025
6
19
[OBJECTIVES] To explore healthcare professionals' perspectives and practices regarding informed consent during childbirth, particularly in the context of increased public awareness and discourse surrounding obstetric violence (OV) in France. [DESIGN] A qualitative study based on semistructured interviews and non-partic...
ETHICS (see Medical Ethics); Midwifery; OBSTETRICS; QUALITATIVE RESEARCH
1.016
176
Medicine
Medicine
2,024
40,537,187
Postural Orthostatic Tachycardia Syndrome and Orthostatic Hypotension Following Hematopoietic Stem Cell Transplantation.
JACC. CardioOncology
JACC CardioOncol
7
4
10.1016/j.jaccao.2025.05.002
eng
2,025
6
null
null
null
null
[BACKGROUND] Postural orthostatic tachycardia (POTS) and orthostatic hypotension (OH) commonly occur after hematopoietic stem cell transplantation (HSCT). [OBJECTIVES] This study sought to determine the prevalence of POTS and OH before HSCT and the incidence of new cases after HSCT. [METHODS] In this single-center, pro...
autonomic dysfunction; bone marrow transplantation; cancer survivorship; diagnosis; mechanisms; orthostatic hypotension; postural orthostatic tachycardia; stem cell transplantation
null
null
null
null
null
40,536,711
Iodothyronine deiodinases in patients with stable chronic obstructive pulmonary disease - preliminary results.
Pharmacological reports : PR
Pharmacol Rep
77
4
10.1007/s43440-025-00754-1
eng
2,025
8
null
2,025
6
19
[BACKGROUND] Different immune/inflammatory molecules play key roles in the development of inflammatory diseases, including chronic obstructive pulmonary disease (COPD). Thyroid hormones (THs) participate in immune/inflammatory reactions and may play a role in COPD. The main TH metabolism reactions are dependent on iodo...
COPD; Cytokines; Inflammation; Iodothyronine deiodinase; Thyroid hormone
0.933
100
Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,536,666
Exploring the therapeutic potential of transcranial direct current stimulation for chronic low back pain: a scoping review.
European journal of physical and rehabilitation medicine
Eur J Phys Rehabil Med
null
null
10.23736/S1973-9087.25.08870-7
eng
2,025
6
19
2,025
6
19
[INTRODUCTION] Chronic low back pain (CLBP) is a common disabling condition, inflicting a substantial socioeconomic burden. Given its association with neuroplastic changes, as evidenced by central and peripheral sensitization, neuromodulatory techniques such as transcranial direct current stimulation (tDCS) have emerge...
null
0.975
79
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation
Health Professions; Medicine
2,024
40,536,454
Age-Specific Mechanisms of Sudden Death Associated With Epilepsy.
JACC. Clinical electrophysiology
JACC Clin Electrophysiol
null
null
10.1016/j.jacep.2025.04.028
eng
2,025
6
2
2,025
6
2
[BACKGROUND] Epilepsy is associated with an increased risk of sudden cardiac death (SCD), which can occur at any age. Due to low numbers of SCD events in longitudinal cohort studies of epilepsy, studies of age-specific clinical profiles have not been performed. [OBJECTIVES] In this study, the authors investigated the d...
epilepsy; population; prevention; risk; sudden death
null
null
null
null
null
40,536,290
Rare species do not disproportionately contribute to phylogenetic diversity in a subalpine plant community.
American journal of botany
Am J Bot
112
6
10.1002/ajb2.70061
eng
2,025
6
null
2,025
6
19
[PREMISE] Within plant communities, few species are abundant, and most are locally rare. Worldwide, 36% of plant species are exceedingly rare and often face high extinction risk. However, the community phylogenetic impact of the loss of rare plants is largely unknown in many systems. We address this gap by investigatin...
Rocky Mountain Biological Laboratory; local abundance; phylogenetic diversity; range size; rare species
0.964
178
Ecology, Evolution, Behavior and Systematics; Plant Science; Genetics
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
2,024
40,590,205
Bi-allelic loss-of-function variants in POC5 cause a syndromic retinal, endocrine, and neuromuscular ciliopathy.
Genetics in medicine : official journal of the American College of Medical Genetics
Genet Med
27
10
10.1016/j.gim.2025.101513
eng
2,025
6
28
2,025
6
28
[PURPOSE] A homozygous loss-of-function (LoF) variant in POC5 was previously described in an individual with retinitis pigmentosa. We identified POC5 variants in 12 probands with a syndromic phenotype. We aim to define the phenotype spectrum and molecular mechanism associated with biallelic POC5 LoF variants. [METHODS]...
Ciliopathy; Insulin resistance; Muscle cramps; Renal disease; Syndrome
2.683
167
Genetics; Medicine
Medicine
2,024
40,589,991
Polysomnography validation of SANSA to detect obstructive sleep apnea.
Frontiers in neurology
Front Neurol
16
null
10.3389/fneur.2025.1592690
eng
2,025
null
null
2,025
6
16
[STUDY OBJECTIVES] Evaluate the performance of a novel home sleep apnea test with embedded ECG (SANSA, Huxley Medical, Inc.) in the diagnosis of obstructive sleep apnea (OSA). [METHODS] This prospective multicenter validation study included 340 participants who underwent simultaneous polysomnography (PSG) and SANSA rec...
atrial fibrillation; cardiac arrhythmia; home sleep apnea testing; sleep apnea; sleep disordered breathing; wearable diagnostic devices
0.993
118
Neurology; Neurology
Medicine; Neuroscience
2,024
40,589,910
Proteins associated with preserved ratio impaired spirometry.
ERJ open research
ERJ Open Res
11
3
10.1183/23120541.01045-2024
eng
2,025
5
null
2,025
6
30
[BACKGROUND] Preserved ratio impaired spirometry (PRISm) is a spirometry pattern of interest regarding incident airflow obstruction and higher mortality risk. We applied a proteomic approach to gain more insight into the biological mechanisms associated with PRISm. [METHODS] From the population-based Swedish Cardiopulm...
null
1.367
52
Pulmonary and Respiratory Medicine
Medicine
2,024
40,589,908
Feasibility and inter-reporter variability of submaximal outcomes derived from cardiopulmonary exercise testing in people with advanced cystic fibrosis lung disease.
ERJ open research
ERJ Open Res
11
3
10.1183/23120541.01001-2024
eng
2,025
5
null
2,025
6
30
[BACKGROUND] Cardiopulmonary exercise testing (CPET) provides prognostic information in people with advanced cystic fibrosis lung disease (pwACFLD). This project aimed to ascertain feasibility and inter-reporter variability in the identification of submaximal CPET outcomes for pwACFLD as potential predictors of prognos...
null
1.367
52
Pulmonary and Respiratory Medicine
Medicine
2,024
40,589,901
Development and validation of a diagnostic prediction model for heart failure-related pleural effusions: the BANCA score.
ERJ open research
ERJ Open Res
11
3
10.1183/23120541.01030-2024
eng
2,025
5
null
2,025
6
30
[AIM] Heart failure (HF) is a common cause of pleural effusion (PE); however, its diagnosis can be challenging owing to overlapping clinical features with other causes. Measuring N-terminal pro-brain natriuretic peptide (NT-proBNP) levels is diagnostically useful, but the optimal cut-off point must be determined. This ...
null
1.367
52
Pulmonary and Respiratory Medicine
Medicine
2,024
40,589,698
Efficacy and Immune-Related Adverse Events of Immune Checkpoint Inhibitors in Patients With Non-small Cell Lung Cancer and Autoimmune Diseases.
Cureus
Cureus
17
5
10.7759/cureus.85067
eng
2,025
5
null
2,025
5
29
[BACKGROUND] Autoimmune diseases (AIDs) are often associated with lung cancer, but their clinical characteristics remain unclear. [PURPOSE] The study aimed to elucidate the clinical features of non-small cell lung cancer (NSCLC) in patients with AIDs. [METHODS] This single-center, retrospective observational study was ...
autoimmune disease; autoimmune disease exacerbation; immune-checkpoint inhibitors; immune-related adverse events (iraes); non-small-cell lung cancer
null
null
null
null
null
40,589,509
Risk factors for mild cognitive impairment in type 2 diabetes: a systematic review and meta-analysis.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
16
null
10.3389/fendo.2025.1617248
eng
2,025
null
null
2,025
6
16
[BACKGROUND] Mild Cognitive Impairment (MCI), a transition between normal aging and dementia, is linked to higher dementia risk and potential reversibility. Type 2 Diabetes Mellitus (T2DM), affecting over 537 million adults worldwide, increases susceptibility to MCI, with higher cognitive decline prevalence in diabetic...
HbA1c; diabetes duration; meta-analysis; mild cognitive impairment; risk factors; type 2 diabetes
1.472
138
Endocrinology, Diabetes and Metabolism
Medicine
2,024
40,589,506
Differential Effects of First and Third Trimester HbA1c Levels on Neonatal Weight and Placental Mediation in Type 1 Diabetes.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
16
null
10.3389/fendo.2025.1595584
eng
2,025
null
null
2,025
6
16
[CONTEXT] In women with type 1 diabetes (T1D), the effects of glycaemic control on neonatal weight and the role of the placenta are not fully understood. [OBJECTIVE] This study explores the relationship between glycaemic control, neonatal weight, and placental weight. [DESIGN] A retrospective observational longitudinal...
meditation; neonatal weight; placenta; pregnancy; type 1 diabetes mellitus
1.472
138
Endocrinology, Diabetes and Metabolism
Medicine
2,024
40,589,299
1-Year Results From a Multicenter Trial of a Polymer Surgical Mitral Valve: Insights Into New Technology.
Journal of the American College of Cardiology
J Am Coll Cardiol
86
7
10.1016/j.jacc.2025.06.017
eng
2,025
8
19
2,025
6
27
[BACKGROUND] Polymer leaflet material may extend the durability of surgical mitral valve replacement (SMVR) to provide stable long-term hemodynamics. The India Mitral Surgical Trial sought to evaluate the safety and performance of a novel polymer leaflet material as part of a surgical mitral valve (MV) prosthesis. [OBJ...
mitral valve diseases; mitral valve replacement; polymer
9.015
512
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,589,193
Home Monitoring of Ascites Using Portable Ultrasound and Telehealth Technology: A Pilot Study.
Journal of clinical ultrasound : JCU
J Clin Ultrasound
null
null
10.1002/jcu.70004
eng
2,025
6
30
2,025
6
30
[PURPOSE] To assess the feasibility of using portable home ultrasound technology during radiologist-led telehealth visits for monitoring ascites in patients requiring repetitive paracentesis procedures. [METHODS] Seven patients with recurring ascites underwent home telehealth visits using a portable ultrasound device a...
ascites; paracentesis; portable ultrasound; telehealth
0.366
69
Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,588,053
Lack of Association Between Dietary Fiber Intake and Kidney Failure Among Patients With Chronic Kidney Disease: The Chronic Kidney Disease-Japan Cohort Study.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation
J Ren Nutr
null
null
10.1053/j.jrn.2025.06.003
eng
2,025
6
28
2,025
6
28
[OBJECTIVE] It remains unclear whether dietary fiber intake improves kidney outcome. The objective of our study was to examine the association between dietary fiber intake and the risk of kidney failure among patients with proteinuric chronic kidney disease (CKD). [METHODS] A total of 2,126 participants in the Chronic ...
chronic kidney disease; dietary fiber; kidney failure; kidney replacement therapy; potassium
0.812
72
Medicine; Nephrology; Nutrition and Dietetics
Medicine; Nursing
2,024
40,587,959
The Relationship between Age and Cognitive Subtypes of Alzheimer Syndrome and Related Dementias.
Dementia and geriatric cognitive disorders
Dement Geriatr Cogn Disord
null
null
10.1159/000547124
eng
2,025
6
30
2,025
6
30
[INTRODUCTION] We aimed to identify cognitive subgroups of clinically diagnosed Alzheimer's disease (Alzheimer syndrome) and related dementias and test if age of presentation influences patterns of cognitive impairment. [METHODS] Participants were individuals with mild cognitive impairment (n = 360), vascular mild cogn...
Cognition; Mild cognitive impairment
0.781
127
Cognitive Neuroscience; Geriatrics and Gerontology; Psychiatry and Mental Health
Medicine; Neuroscience
2,024
40,587,946
A Novel Hydrodynamic Approach for the Evaluation of Microvascular Resistance during Provocative Spasm Testing.
Cardiology
Cardiology
null
null
10.1159/000547197
eng
2,025
6
30
2,025
6
30
[INTRODUCTION] Intracoronary acetylcholine provocative testing is the gold standard method for the assessment of epicardial and/or microvascular spasm, with the latter diagnosed when there is ACh-induced chest pain and ischaemic ECG changes in the absence of epicardial spasm. Whilst epicardial spasm can be visualised, ...
null
0.596
77
Cardiology and Cardiovascular Medicine; Pharmacology
Medicine
2,024
40,587,472
The effect of bone marrow mesenchymal stem cell-derived extracellular vesicles on bone mineral density and microstructure in osteoporosis: A systematic review and meta-analysis of preclinical studies.
PloS one
PLoS One
20
6
10.1371/journal.pone.0327011
eng
2,025
null
null
2,025
6
30
[OBJECTIVE] The treatment of osteoporosis is challenged by limited bone regeneration and side effects. Bone marrow mesenchymal stem cell-derived extracellular vesicles (BMSC-EVs) have gained widespread attention as a potential therapeutic approach. This study aims to evaluate the effects of BMSC-EVs on bone density, tr...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
40,587,130
Clinical Outcomes of Perioperative Immunotherapy in Resectable Non-Small Cell Lung Cancer.
JAMA network open
JAMA Netw Open
8
6
10.1001/jamanetworkopen.2025.17953
eng
2,025
6
2
2,025
6
2
[IMPORTANCE] Lung cancer remains a leading cause of cancer-related mortality, with early-stage non-small cell lung cancer (NSCLC) accounting for 40% to 45% of new diagnoses. Despite the adoption of perioperative chemoimmunotherapy, clinical data on its use and outcomes remain limited. [OBJECTIVE] To evaluate clinical p...
null
3.546
154
Medicine
Medicine
2,024
40,587,121
Impact of age, sex, and urban environment on allergen-specific IgE profiles to grass pollen components: a cross-sectional study in Northern Italy.
Minerva medica
Minerva Med
null
null
10.23736/S0026-4806.25.09673-9
eng
2,025
6
30
2,025
6
30
[BACKGROUND] Asthma and rhino-conjunctivitis are frequently triggered by sensitization to airborne allergens, particularly grass pollens. This study aimed to assess whether age, sex, and living environment influence allergen-specific IgE responses to grass pollen components, using a molecular diagnostic approach. [METH...
null
0.502
43
Medicine
Medicine
2,024
40,587,067
Do cardiovascular disease patients return to pre-lockdown sedentary levels? A prospective cohort study.
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
Neth Heart J
33
7-8
10.1007/s12471-025-01966-z
eng
2,025
7
null
2,025
6
30
[BACKGROUND] The COVID-19 lockdown negatively impacted physical activity (PA) and sedentary behaviour (SB) levels of the Dutch patients with cardiovascular diseases (CVD), but little is known whether these levels returned to pre-pandemic levels. In this study, we evaluated changes in SB and moderate-to-vigorous PA (MVP...
COVID-19; Cardiovascular Disease; Pandemics; Physical inactivity; Sedentary time
null
null
null
null
null
40,587,056
Efficacy of nodal dissection for locoregional gastric neuroendocrine carcinoma: a multicenter retrospective observational study.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Gastric Cancer
null
null
10.1007/s10120-025-01636-4
eng
2,025
6
30
2,025
6
30
[BACKGROUND] Gastric neuroendocrine carcinoma (NEC) is a rare and aggressive malignancy for which no standard treatment has been established for locoregional disease. This multicenter retrospective study aimed to evaluate the prognostic relevance and therapeutic efficacy of lymph node dissection in this setting. [METHO...
Gastrectomy; Gastric neuroendocrine carcinoma; Lymph node dissection; Therapeutic value index
2.489
106
Cancer Research; Gastroenterology; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,587,027
Late remission and "late onset" of hypoparathyroidism after total and completion thyroidectomy: a retrospective cohort study of 1060 patients from a tertiary referral center.
Endocrine
Endocrine
null
null
10.1007/s12020-025-04330-8
eng
2,025
6
30
2,025
6
30
[PURPOSE] This single-center retrospective study investigates the incidence of hypoparathyroidism after bilateral thyroidectomy at a tertiary referral center over one decade, including risk factors, time to recovery, and reasons for belated treatment initiation in seemingly "late onset" hypoparathyroidism. [METHODS] Pa...
Hypoparathyroidism; Parathyroid glands; Postoperative complications/diagnosis; Prevalence; Retrospective studies; Thyroidectomy/adverse effects
0.971
107
Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,586,862
Comparison of postoperative analgesic efficacy between PENG block and suprascapular nerve block in shoulder arthroscopy: a randomized controlled trial.
Minerva anestesiologica
Minerva Anestesiol
null
null
10.23736/S0375-9393.25.18879-2
eng
2,025
6
30
2,025
6
30
[BACKGROUND] Patients commonly experience moderate to severe pain following shoulder arthroscopy. It is possible to reduce opioid consumption and hospital stay by using regional analgesia techniques in pain management. Currently, the suprascapular nerve block (SSNB) is widely used as an effective method to provide anal...
null
0.633
73
Anesthesiology and Pain Medicine
Medicine
2,024
40,586,762
Reference intervals for lipid biomarkers in youth athletes.
The Journal of sports medicine and physical fitness
J Sports Med Phys Fitness
null
null
10.23736/S0022-4707.25.16150-1
eng
2,025
6
30
2,025
6
30
[BACKGROUND] It is known that lipid profile is influenced by physical exercise. In addition, adolescent athletes undergo significant hormonal changes that also affect their lipid profile. In our study, we used a sample of elite athletes under 18 years old (2281 f, 2986 m) from different sports disciplines to calculate ...
null
0.495
79
Physical Therapy, Sports Therapy and Rehabilitation; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,024
40,586,508
Functional ability of the elderly and related factors in the Subcarpathian Region.
Annals of agricultural and environmental medicine : AAEM
Ann Agric Environ Med
32
2
10.26444/aaem/202317
eng
2,025
6
27
2,025
3
26
[INTRODUCTION AND OBJECTIVE] Functional ability is the ability to independently perform basic life activities, such as moving, eating, controlling the physiological functions of the body, and maintaining body hygiene. Functional ability is measured by the living environment's degree of independence and self-reliance. T...
elderly; functional ability; risk of falls
0.386
69
Ecology, Evolution, Behavior and Systematics; Public Health, Environmental and Occupational Health; Waste Management and Disposal
Agricultural and Biological Sciences; Environmental Science; Medicine
2,024
40,586,466
Comparative evaluation of digital and tray impression technique as a method of recording anatomical details of cleft lip and palate in neonates - A randomized controlled clinical trial.
Journal of the Indian Society of Pedodontics and Preventive Dentistry
J Indian Soc Pedod Prev Dent
43
2
10.4103/jisppd.jisppd_533_24
eng
2,025
4
1
2,025
6
30
[BACKGROUND] Cleft lip and palate (CLP), affecting 1 in 700-1000 live births, cause feeding difficulties in neonates due to oronasal communication, requiring feeding plates. Traditional impression methods risk material aspiration and distortion. [AIM] The study aimed to assess the efficacy of digital impressions for re...
Cleft lip and palate; digital impression technique; randomized controlled trial
null
null
null
null
null
40,586,464
Effect of Lactobacillus reuteri probiotic on gingival index and Interleukin-1β levels of children with thalassemia experiencing gingivitis.
Journal of the Indian Society of Pedodontics and Preventive Dentistry
J Indian Soc Pedod Prev Dent
43
2
10.4103/jisppd.jisppd_146_25
eng
2,025
4
1
2,025
6
30
[CONTEXT] Thalassemia is a genetic blood disorder caused by gene mutation leading to chronic anemia, and patients will need routine blood transfusions as a lifetime supportive therapy. Previous studies show high prevalence of periodontal disease in patients who receive routine blood transfusions. Recent studies found p...
Gingival index; gingivitis; interleukin-1; thalassemia major
null
null
null
null
null
40,586,107
Impact of instrumentation kinematics on post endodontic pain-an umbrella review with stratification of evidence and sensitivity analysis.
Journal of oral biology and craniofacial research
J Oral Biol Craniofac Res
15
4
10.1016/j.jobcr.2025.06.008
eng
2,025
null
null
2,025
6
14
[BACKGROUND] Our umbrella review examines the impact of instrumentation kinematics on postoperative pain in endodontic treatment by synthesizing current evidence from systematic reviews and meta-analyses. [METHODS] We performed an extensive search across six major electronic databases up to March 2025, focusing on Engl...
Endodontics; Postoperative pain; Reciprocating instrumentation; Root canal therapy; Rotary instrumentation; Systematic review
0.549
39
Dentistry; Otorhinolaryngology
Dentistry; Medicine
2,024
40,585,942
Association of hepatic steatosis with increased plasma xanthine oxidoreductase activity: MedCity21 health examination registry.
Metabolism open
Metabol Open
27
null
10.1016/j.metop.2025.100374
eng
2,025
9
null
2,025
6
13
[BACKGROUND] Steatotic liver disease, characterized by hepatic steatosis, increases the risk of metabolic and cardiovascular diseases. We previously reported that the plasma activity of xanthine oxidoreductase (XOR), primarily expressed in the human liver, is also associated with these diseases. The present study exami...
Hepatic fibrosis; Hepatic steatosis; Liver enzyme; Plasma XOR activity
null
null
null
null
null
40,585,843
Demographic trends in mortality due to ovarian cancer in the United States, 1999-2020.
World journal of clinical oncology
World J Clin Oncol
16
6
10.5306/wjco.v16.i6.108393
eng
2,025
6
24
null
null
null
[BACKGROUND] Ovarian carcinoma has the highest mortality rate among all gynecological cancers. Several reproductive and hormonal risk factors, including early menarche, late menopause, limited use of oral contraceptives, and a low pregnancy rate, have been identified as contributors to the increased susceptibility to o...
Age-adjusted mortality rate; Crude mortality rate; Demographic trends; Mortality; Ovarian cancer; Ovarian carcinoma; United States
null
null
null
null
null
40,585,547
Machine-learning detection of stress severity expressed on a continuous scale using acoustic, verbal, visual, and physiological data: lessons learned.
Frontiers in psychiatry
Front Psychiatry
16
null
10.3389/fpsyt.2025.1548287
eng
2,025
null
null
2,025
6
13
[BACKGROUND] Early detection of elevated acute stress is necessary if we aim to reduce consequences associated with prolonged or recurrent stress exposure. Stress monitoring may be supported by valid and reliable machine-learning algorithms. However, investigation of algorithms detecting stress severity on a continuous...
acoustic; machine learning; multimodal; physiology; stress; verbal; video
1.192
134
Psychiatry and Mental Health
Medicine
2,024
40,585,345
Topical Bixa orellana for Postoperative Wound Healing: A Prospective Randomized Controlled Trial.
Foot & ankle orthopaedics
Foot Ankle Orthop
10
2
10.1177/24730114251345821
eng
2,025
4
null
2,025
6
26
[BACKGROUND] Numerous ointments may be applied to surgical incisions in the postoperative period to minimize scar formation. There is little evidence assessing their efficacy on wound healing following foot and ankle procedures. This trial was conducted to assess the efficacy of Bixa orellana (Urucu) ointment in the tr...
Bixa orellana (Urucu); wound healing
null
null
null
null
null
40,585,269
Prevalence of Hypertension and its Associated Factors among Public Vehicle Drivers in Western Nepal: A Population-based Study.
Research square
Res Sq
null
null
10.21203/rs.3.rs-6310909/v1
eng
2,025
6
9
2,025
6
9
[INTRODUCTION] Hypertension presents a major global health problem, impacting persons across all ages, backgrounds, and lifestyles. Occupational risk factors interlinked to hypertension are poorly researched in Nepal. The study aimed to measure the prevalence of hypertension and its associated factors among public vehi...
Drivers; High Blood Pressure; Hypertension; Nepal; Prevalence
null
null
null
null
null
40,584,899
Chloroquine inhibits salinomycin-induced autophagy for collaborative anticancer effect in breast cancer.
BioImpacts : BI
Bioimpacts
15
null
10.34172/bi.30821
eng
2,025
null
null
2,025
5
25
[INTRODUCTION] Breast cancer (BC) presents significant morbidity and mortality challenges. Autophagy plays a contradictory role in BC. The chemotherapeutic agent salinomycin exhibits anticancer effects, but its effectiveness is limited by over-activation of autophagy. This study aimed to investigate the effects and mec...
Autophagy; Breast cancer; Chloroquine; PI3K/AKT/mTOR signaling pathway; Salinomycin
0.542
48
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmaceutical Science
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,584,683
Biomechanical Analysis of the Rebar Technique for Tibial Defects in Total Knee Arthroplasty.
Arthroplasty today
Arthroplast Today
34
null
10.1016/j.artd.2025.101741
eng
2,025
8
null
2,025
6
12
[BACKGROUND] Tibial defects in total knee arthroplasty require appropriate fixation for stability. Smaller defects are treated with cement or a screw and cement construct (rebar technique), while larger defects may require augments. Prior studies validate screws and cement for small defects but caution against use beyo...
Biomechanical; Cemented; Defect; Primary; Total knee arthroplasty
0.918
32
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
40,584,584
Enhanced ventricular synchrony and myocardial function with bipolar left bundle area pacing: a comparative study of anodal ring capture versus unipolar pacing.
European heart journal open
Eur Heart J Open
5
3
10.1093/ehjopen/oeaf077
eng
2,025
5
null
2,025
6
18
[AIMS] Cardiac pacing aims to replicate physiological heart rhythm. While left bundle area pacing (LBAP) enhances left ventricular (LV) activation, it often struggles to fully address interventricular dyssynchrony. Bipolar LBAP with anodal ring capture (LBAP-ARC) offers a potential solution by synchronously activating ...
Anodal ring capture; Bipolar pacing; Left bundle area pacing; Myocardial strain; Synchronization; Ventricular synchrony
null
null
null
null
null
40,584,441
Hepatoprotective effects of Curcuma xanthorrhiza Roxb. extract via free radical scavenger, inhibiting apoptosis and inflammation mechanisms in acetaminophen-induced liver injury.
Iranian journal of basic medical sciences
Iran J Basic Med Sci
28
8
10.22038/ijbms.2025.82500.17833
eng
2,025
null
null
null
null
null
[OBJECTIVES] Acetaminophen (APAP)-mediated liver injury poses a significant public health concern. Curcuma xanthorrhiza extract (CXE) has been traditionally used for its hepatoprotective properties. This research aimed to assess the hepatoprotective effects of CXE in APAP-mediated hepatotoxicity by investigating the mo...
Acetaminophen Antioxidants; Apoptosis; Curcuma xanthorrhiza; Free radical scavengers Liver injury
null
null
null
null
null
40,583,997
Eravacycline as a last resort for difficult-to-treat resistant Acinetobacter baumannii infections in critically ill patients: three case reports with pharmacokinetic insights.
JAC-antimicrobial resistance
JAC Antimicrob Resist
7
3
10.1093/jacamr/dlaf095
eng
2,025
6
null
2,025
6
17
[OBJECTIVES] To describe eravacycline use as a salvage treatment for ventilator-associated pneumonia (VAP) caused by difficult-to-treat resistant (DTR) Acinetobacter baumannii in critically ill patients. [METHODS] We reported three cases of DTR A. baumannii VAP with multiple organ failure treated with eravacycline. Pat...
null
1.063
29
Infectious Diseases; Microbiology; Immunology; Immunology and Allergy; Microbiology
Immunology and Microbiology; Medicine
2,024
40,583,886
Effect of Acute Administration of Caffeine on Neuropathic Pain and the Role of Nitric Oxide Pathway in an Animal Model of Chronic Constriction Injury.
Basic and clinical neuroscience
Basic Clin Neurosci
15
5
10.32598/bcn.2024.5523.1
eng
2,024
null
null
2,024
9
1
[INTRODUCTION] Partial peripheral nerve injury often results in chronic pain, including hyperalgesia and allodynia. Caffeine, as a non-selective antagonist of adenosine receptors (ARs), has protective effects on neuropathic pain. Since nitric oxide (NO) is partially involved in the central effects of caffeine, we inves...
Adenosine receptors (ARs); Caffeine; L-Arginine; L-NAME; Neuropathic pain; Nitric oxide (NO)
0.348
31
Neurology; Cellular and Molecular Neuroscience
Medicine; Neuroscience
2,024
40,583,800
Influence of Spirituality on Severity, Quality of Life, and Mental Health of Tinnitus Patients.
The Annals of otology, rhinology, and laryngology
Ann Otol Rhinol Laryngol
null
null
10.1177/00034894251349411
eng
2,025
6
30
2,025
6
30
[OBJECTIVE] Despite the growing evidence on the role of spiritual and religious beliefs on physical and mental health outcomes, this remains inadequately explored in the field of otolaryngology, particularly for chronic conditions such as tinnitus. This study aims to investigate the influence of spiritual and religious...
mental health; otolaryngology; religion; spirituality; tinnitus
0.528
107
Otorhinolaryngology; Medicine
Medicine
2,024
40,583,745
Barriers to seeking mental health services among young persons with mental disorders in South India: a qualitative study.
East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan
East Asian Arch Psychiatry
35
2
10.12809/eaap2543
eng
2,025
6
null
null
null
null
[OBJECTIVES] To explore barriers to seeking mental health services among young people in Chennai, South India, using a qualitative study. [METHODS] Young people aged 18 to 24 years with a diagnosis of any mental disorder were purposively recruited from a tertiary mental health centre in Chennai, South India, between Ap...
Adolescent; Help-seeking behavior; Mental disorders; Mental health services; Qualitative research
null
null
null
null
null
40,583,552
A 6-month supported online program for the treatment of persecutory delusions: Feeling Safer.
Psychological medicine
Psychol Med
55
null
10.1017/S0033291725100676
eng
2,025
6
30
2,025
6
30
[BACKGROUND] Based on an efficacious face-to-face theory-driven psychological therapy for persecutory delusions in the context of psychosis, we set out to develop a scalable guided 6-month online program. The aim was an intervention that patients can easily access and use, produces large clinical effects, and can be su...
cognitive therapy; digital intervention; persecutory delusions; psychosis; schizophrenia
2.424
251
Applied Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
40,583,430
Assessment of Imaging Accuracy Using Different Intraoral Scanner Streaming Modes: An In Vitro Study.
The journal of contemporary dental practice
J Contemp Dent Pract
26
4
10.5005/jp-journals-10024-3863
eng
2,025
4
1
2,025
4
1
[AIM] This in vitro study evaluated the accuracy of two intraoral scanners with different streaming modes (CEREC Omnicam, Dentsply-Sirona, USA; video mode) and (Shining 3D, Aoralscan, China; image mode). [MATERIALS AND METHODS] Three sets of acrylic maxillary typodont were uniformly reduced with known axial wall taper ...
Digital impression; Scanning accuracy
0.353
53
Dentistry
Dentistry
2,024
40,582,954
Lower rate of pancreatobiliary complications after sludge and microlithiasis pancreatitis compared to gallstone pancreatitis.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Dig Liver Dis
null
null
10.1016/j.dld.2025.06.005
eng
2,025
6
28
2,025
6
28
[BACKGROUND AND AIMS] Cholecystectomy is recommended to prevent recurrence of biliary pancreatitis, but supporting evidence is limited for sludge- and microlithiasis-induced acute pancreatitis (AP). This study aimed to compare relapse patterns and risk factors between patients with sludge/microlithiasis-induced AP and ...
Acute pancreatitis; Biliary pancreatitis; Gallstones; Microlithiasis; Sludge
1.091
113
Gastroenterology; Hepatology
Medicine
2,024
40,582,925
Fibromyalgia: Advances in pathophysiology, diagnostic biomarkers, genetic insights, multisystemic involvement, and treatment updates and multidisciplinary interventions.
Disease-a-month : DM
Dis Mon
null
null
10.1016/j.disamonth.2025.101965
eng
2,025
6
28
2,025
6
28
[BACKGROUND] This systematic review examines the pathophysiology, biomarkers, genetic insights, and treatment strategies for fibromyalgia, highlighting central sensitization, neuroinflammation, comorbidities, and the effectiveness of multidisciplinary interventions, including pharmacological and non-pharmacological the...
Biomarkers; Chronic pain; Fibromyalgia; Genetics; Multidisciplinary treatment; Pathophysiology
null
null
null
null
null