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3001 | The review garnered media attention and conflicting opinions from other researchers. Yinka Ebo of Cancer Research UK disputed the findings, concluding that "there is still not enough evidence to suggest that using mouthwash that contains alcohol will increase the risk of mouth cancer". Studies conducted in 1985, 1995, 2003, and 2012 did not support an association between alcohol-containing mouth rinses and oral cancer. Andrew Penman, chief executive of The Cancer Council New South Wales, called for further research on the matter. In a March 2009 brief, the American Dental Association said "the available evidence does not support a connection between | Mouthwash | [
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3002 | oral cancer and alcohol-containing mouthrinse". Many newer brands of mouthwash are alcohol free, not just in response to consumer concerns about oral cancer, but also to cater for religious groups who abstain from alcohol consumption. In painful oral conditions such as aphthous stomatitis, analgesic mouthrinses (e.g. benzydamine mouthwash, or "Difflam") are sometimes used to ease pain, commonly used before meals to reduce discomfort while eating. Acts as a buffer Betamethasone is sometimes used as an anti-inflammatory, corticosteroid mouthwash. It may be used for severe inflammatory conditions of the oral mucosa such as the severe forms of aphthous stomatitis. Cetylpyridinium chloride | Mouthwash | [
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3003 | containing mouthwash (e.g. 0.05%) is used in some specialized mouthwashes for halitosis. Cetylpyridinium chloride mouthwash has less anti-plaque effect than chlorhexidine and may cause staining of teeth, or sometimes an oral burning sensation or ulceration. Chlorhexidine digluconate is a chemical antiseptic and is used in a 0.12-0.2% solution as a mouthwash. However, there is no evidence to support that higher concentrations are more effective in controlling dental plaque and gingivitis. It has anti-plaque action, but also some anti-fungal action. It is especially effective against Gram-negative rods. The proportion of Gram-negative rods increase as gingivitis develops so it is also used | Mouthwash | [
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3004 | to reduce gingivitis. It is sometimes used as an adjunct to prevent dental caries and to treat gingivitis periodontal disease, although it does not penetrate into periodontal pockets well. Chlorhexidine mouthwash alone is unable to prevent plaque, so it is not a substitute for regular toothbrushing and flossing. Instead, chlorhexidine is more effective used as an adjunctive treatment with tooth brushing and flossing. In the short term, if toothbrushing is impossible due to pain, as may occur in primary herpetic gingivostomatitis, chlorhexidine is used as temporary substitute for other oral hygiene measures. It is not suited for use in acute | Mouthwash | [
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3005 | necrotizing ulcerative gingivitis, however. Rinsing with chlorhexidine mouthwash before a tooth extraction reduces the risk of dry socket, a painful condition where the blood clot is lost from an extraction socket and bone is exposed to the oral cavity. Other uses of chlorhexidine mouthwash include prevention of oral candidiasis in immunocompromised persons, treatment of denture-related stomatitis, mucosal ulceration/erosions and oral mucosal lesions, general burning sensation and many other uses. Chlorhexidine has good "substantivity" (the ability of a mouthwash to bind to hard and soft tissues in the mouth). However, chlorhexidine binds to tannins, meaning that prolonged use in persons who | Mouthwash | [
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3006 | consume coffee, tea or red wine is associated with extrinsic staining (i.e. removable staining) of teeth. Chlorhexidine mouthwash can also cause taste disturbance and/or alteration. Chlorhexidine is rarely associated with other issues like overgrowth of enterobacteria in persons with leukemia, desquamation and irritation of oral mucosa, salivary gland pain and swelling, and hypersensitivity reactions including anaphylaxis. A randomized clinical trial conducted in Rabat university in Morocco found better results in plaque inhibition when chlorohexidine with alcohol base 0.12% was used , when compared to an alcohol free 0.1% chlorhexidine mouthrinse. Chlorhexidine mouthrinses increase staining score of teeth over a period | Mouthwash | [
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3007 | of time. Hexetidine also has anti-plaque, analgesic, astringent and anti-malodor properties but is considered as an inferior alternative to Chlorhexidine. In traditional Ayurvedic medicine, the use of oil mouthwashes is called "Kavala" ("oil swishing") or "Gandusha", and this practice has more recently been re-marketed by the complimentary and alternative medicine industry as "oil pulling". Its promoters claim it works by "pulling out" "toxins", which are known as ama in Ayurvedic medicine, and thereby reducing inflammation. Ayurvedic literature suggests oil pulling is capable of improving oral and systemic health, including a benefit in conditions such as headaches, migraines, diabetes mellitus, asthma, | Mouthwash | [
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3008 | and acne, as well as whitening teeth. Oil pulling has received little study and there is little evidence to support claims made by the technique's advocates. When compared with chlorhexidine in one small study, it was found to be less effective at reducing oral bacterial load, otherwise the health claims of oil pulling have failed scientific verification or have not been investigated. There is a report of lipid pneumonia caused by accidental inhalation of the oil during oil pulling. The mouth is rinsed with approximately one tablespoon of oil for 10–20 minutes then spat out. Sesame oil, coconut oil and | Mouthwash | [
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3009 | ghee are traditionally used, but newer oils such as sunflower oil are also used. Phenolic compounds include essential oil constituents that have some antibacterial properties, like phenol, thymol, eugenol, eucalyptol or menthol. Essential oils are oils which have been extracted from plants. Mouthwashes based on essential oils could be more effective than traditional mouthcare - for anti-gingival treatments. They have been found effective in reducing halitosis, and are being used in several commercial mouthwashes. Anti-cavity mouth rinses use fluoride to protect against tooth decay. Most people using fluoridated toothpastes do not require fluoride-containing mouth rinses, rather fluoride mouthwashes are sometimes | Mouthwash | [
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3010 | used in individuals who are at high risk of dental decay, due to dental caries or people with xerostomia. Flavoring agents include sweeteners such as sorbitol, sucralose, sodium saccharin, and xylitol, which stimulate salivary function due to their sweetness and taste and helps restore the mouth to a neutral level of acidity. Xylitol rinses double as a bacterial inhibitor and have been used as substitute for Alcohol to avoid dryness of mouth associated with Alcohol. Hydrogen peroxide can be used as an oxidizing mouthwash (e.g. Peroxyl, 1.5%). It kills anaerobic bacteria, and also has a mechanical cleansing action when it | Mouthwash | [
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3011 | froths as it comes into contact with debris in mouth. It is often used in the short term to treat acute necrotising ulcerative gingivitis. Side effects with prolonged use might occur, including hypertrophy of the lingual papillae. Enzymes and proteins such as Lactoperoxidase, Lysozyme, Lactoferrin have been used in mouthrinses (e.g. Biotene) to reduce oral bacteria and hence the acid produced by bacteria. Oral lidocaine is useful for the treatment of mucositis symptoms (inflammation of mucous membranes) that is induced by radiation or chemotherapy. There is evidence that lidocaine anesthetic mouthwash has the potential to be systemically absorbed when it | Mouthwash | [
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3012 | was tested in patients with oral mucositis who underwent a bone marrow transplant. Methyl salicylate functions as an anti-septic, anti-inflammatory, analgesic, flavoring, and fragrance Methyl salicylate]] has some anti-plaque action, but less than chlorhexidine. Methyl salicylate does not not stain teeth. Nystatin suspension is an antifungal ingredient used for the treatment of oral candidiasis. A randomized clinical trial found promising results in controlling and reducing dentine hypersensitivity when potassium oxalate mouthrinse was used in conjugation with toothbrushing. A 2005 study found that gargling three times a day with simple water or with a Povidone-iodine solution was effective in preventing upper | Mouthwash | [
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3013 | respiratory infection and decreasing the severity of symptoms if contracted. Other sources attribute the benefit to a simple placebo effect. Sanguinarine-containing mouthwashes are marketed as anti-plaque and anti-malodor. It is a toxic alkaloid herbal extract, obtained from plants such as "Sanguinaria canadensis" (Bloodroot), "Argemone mexicana" (Mexican Prickly Poppy) and others. However, its use is strongly associated with development of leukoplakia (a white patch in the mouth), usually in the buccal sulcus. This type of leukoplakia has been termed "sanguinaria-associated keratosis" and more than 80% of people with leukoplakia in the vestibule of the mouth have used this substance. Upon stopping | Mouthwash | [
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3014 | contact with the causative substance, the lesions may persist for years. Although this type of leukoplakia may show dysplasia, the potential for malignant transformation is unknown. Ironically, elements within the complimentary and alternative medicine industry promote the use of sanguinaria as a therapy for cancer. Sodium bicarbonate is sometimes combined with salt to make a simple homemade mouthwash, indicated for any of the reasons that a salt water mouthwash might be used. Pre-mixed mouthwashes of 1% sodium bicarbonate and 1.5% sodium chloride in aqueous solution are marketed, although pharmacists will easily be able to produce such a formulation from the | Mouthwash | [
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3015 | base ingredients when required. Sodium bicarbonate mouthwash is sometimes used to remove viscous saliva and to aid visualization of the oral tissues during examination of the mouth. Salt water mouth wash is made by dissolving 0.5–1 teaspoon of table salt into a cup of water, which is as hot as possible without causing discomfort in the mouth. Saline has a mechanical cleansing action and an antiseptic action as it is a hypertonic solution in relation to bacteria, which undergo lysis. The heat of the solution produces a therapeutic increase in blood flow (hyperemia) to the surgical site, promoting healing. Hot | Mouthwash | [
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3016 | salt water mouthwashes also encourage the draining of pus from dental abscesses. Conversely, if heat is applied on the side of the face (e.g., hot water bottle) rather than inside the mouth, it may cause a dental abscess to drain extra-orally, which is later associated with an area of fibrosis on the face (see cutaneous sinus of dental origin). Gargling with salt water is said to reduce the symptoms of a sore throat. Hot salt water mouth baths (or hot salt water mouth washes, sometimes abbreviated to "HSWMW") are also routinely used after oral surgery, to keep food debris out | Mouthwash | [
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3017 | of healing wounds and to prevent infection. Some oral surgeons consider salt water mouthwashes the mainstay of wound cleanliness after surgery. In dental extractions, hot salt water mouthbaths should start about 24 hours after a dental extraction. The term "mouth bath" implies that the liquid is passively held in the mouth rather than vigorously swilled around, which could dislodge a blood clot. Once the blood clot has stabilized, the mouth wash can be used more vigorously. These mouthwashes tend to be advised about 6 times per day, especially after meals to remove food from the socket. Sodium lauryl sulfate (SLS) | Mouthwash | [
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3018 | is used as a foaming agent in many oral hygiene products including many mouthwashes. Some may suggest that it is probably advisable to use mouthwash at least an hour after brushing with toothpaste when the toothpaste contains SLS, since the anionic compounds in the SLS toothpaste can deactivate cationic agents present in the mouthrinse. Sucralfate is a mucosal coating agent, composed of an aluminum salt of sulfated sucrose. It is not recommended for use in the prevention of oral mucositis in head and neck cancer patients receiving radiotherapy or chemoradiation due to a lack of efficacy found in a well-designed, | Mouthwash | [
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3019 | randomized controlled trial. Tetracycline is an antibiotic which may sometimes be used as a mouthwash in adults (it causes red staining of teeth in children). It is sometimes use for herpetiforme ulceration (an uncommon type of aphthous stomatitis), but prolonged use may lead to oral candidiasis as the fungal population of the mouth overgrows in the absence of enough competing bacteria. Similarly, Minocycline mouthwashes of 0.5% concentrations can relieve symptoms of recurrent aphthous stomatitis. Erythromycin is similar. 4.8% tranexamic acid solution is sometimes used as an antifibrinolytic mouthwash to prevent bleeding during and after oral surgery in persons with coagulopathies | Mouthwash | [
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3020 | (clotting disorders) or who are taking anticoagulants (blood thinners such as warfarin). Triclosan is a non-ionic chlorinate bisphenol antiseptic found in some mouthwashes. When used in mouthwash (e.g. 0.03%), there is moderate substantivity, broad spectrum anti-bacterial action, some anti-fungal action and significant anti-plaque effect, especially when combined with copolymer or zinc citrate. Triclosan does not cause staining of the teeth. The safety of triclosan has been questioned. Astringents like zinc chloride provide a pleasant-tasting sensation and shrink tissues. Zinc when used in combination with other anti-septic agents can limit the build-up of tartar Mouthwash Mouthwash, mouth rinse, oral rinse, or | Mouthwash | [
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3021 | Alexander the Great Alexander III of Macedon (; 20/21 July 356 BC – 10/11 June 323 BC), commonly known as Alexander the Great (), was a king ("basileus") of the ancient Greek kingdom of Macedon and a member of the Argead dynasty. He was born in Pella in 356 BC and succeeded his father Philip II to the throne at the age of twenty. He spent most of his ruling years on an unprecedented military campaign through Asia and northeast Africa, and he created one of the largest empires of the ancient world by the age of thirty, stretching from | "Alexander the Great" | [
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3022 | Greece to northwestern India. He was undefeated in battle and is widely considered one of history's most successful military commanders. During his youth, Alexander was tutored by Aristotle until age 16. After Philip's assassination in 336 BC, he succeeded his father to the throne and inherited a strong kingdom and an experienced army. Alexander was awarded the generalship of Greece and used this authority to launch his father's pan-Hellenic project to lead the Greeks in the conquest of Persia. In 334 BC, he invaded the Achaemenid Empire (Persian Empire) and began a series of campaigns that lasted ten years. Following | "Alexander the Great" | [
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3023 | the conquest of Anatolia, Alexander broke the power of Persia in a series of decisive battles, most notably the battles of Issus and Gaugamela. He subsequently overthrew Persian King Darius III and conquered the Achaemenid Empire in its entirety. At that point, his empire stretched from the Adriatic Sea to the Indus River. He endeavored to reach the "ends of the world and the Great Outer Sea" and invaded India in 326 BC, winning an important victory over the Pauravas at the Battle of the Hydaspes. He eventually turned back at the demand of his homesick troops. Alexander died in | "Alexander the Great" | [
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3024 | Babylon in 323 BC, the city that he planned to establish as his capital, without executing a series of planned campaigns that would have begun with an invasion of Arabia. In the years following his death, a series of civil wars tore his empire apart, resulting in the establishment of several states ruled by the Diadochi, Alexander's surviving generals and heirs. Alexander's legacy includes the cultural diffusion and syncretism which his conquests engendered, such as Greco-Buddhism. He founded some twenty cities that bore his name, most notably Alexandria in Egypt. Alexander's settlement of Greek colonists and the resulting spread of | "Alexander the Great" | [
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3025 | Greek culture in the east resulted in a new Hellenistic civilization, aspects of which were still evident in the traditions of the Byzantine Empire in the mid-15th century AD and the presence of Greek speakers in central and far eastern Anatolia until the 1920s. Alexander became legendary as a classical hero in the mold of Achilles, and he features prominently in the history and mythic traditions of both Greek and non-Greek cultures. He became the measure against which military leaders compared themselves, and military academies throughout the world still teach his tactics. He is often ranked among the most influential | "Alexander the Great" | [
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3026 | people in history. Alexander was born on the sixth day of the ancient Greek month of Hekatombaion, which probably corresponds to 20July 356 BC, although the exact date is disputed, in Pella, the capital of the Kingdom of Macedon. He was the son of the king of Macedon, Philip II, and his fourth wife, Olympias, the daughter of Neoptolemus I, king of Epirus. Although Philip had seven or eight wives, Olympias was his principal wife for some time, likely because she gave birth to Alexander. Several legends surround Alexander's birth and childhood. According to the ancient Greek biographer Plutarch, on | "Alexander the Great" | [
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3027 | the eve of the consummation of her marriage to Philip, Olympias dreamed that her womb was struck by a thunder bolt that caused a flame to spread "far and wide" before dying away. Sometime after the wedding, Philip is said to have seen himself, in a dream, securing his wife's womb with a seal engraved with a lion's image. Plutarch offered a variety of interpretations of these dreams: that Olympias was pregnant before her marriage, indicated by the sealing of her womb; or that Alexander's father was Zeus. Ancient commentators were divided about whether the ambitious Olympias promulgated the story | "Alexander the Great" | [
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3028 | of Alexander's divine parentage, variously claiming that she had told Alexander, or that she dismissed the suggestion as impious. On the day Alexander was born, Philip was preparing a siege on the city of Potidea on the peninsula of Chalcidice. That same day, Philip received news that his general Parmenion had defeated the combined Illyrian and Paeonian armies, and that his horses had won at the Olympic Games. It was also said that on this day, the Temple of Artemis in Ephesus, one of the Seven Wonders of the World, burnt down. This led Hegesias of Magnesia to say that | "Alexander the Great" | [
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3029 | it had burnt down because Artemis was away, attending the birth of Alexander. Such legends may have emerged when Alexander was king, and possibly at his own instigation, to show that he was superhuman and destined for greatness from conception. In his early years, Alexander was raised by a nurse, Lanike, sister of Alexander's future general Cleitus the Black. Later in his childhood, Alexander was tutored by the strict Leonidas, a relative of his mother, and by Lysimachus of Acarnania. Alexander was raised in the manner of noble Macedonian youths, learning to read, play the lyre, ride, fight, and hunt. | "Alexander the Great" | [
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3030 | When Alexander was ten years old, a trader from Thessaly brought Philip a horse, which he offered to sell for thirteen talents. The horse refused to be mounted, and Philip ordered it away. Alexander however, detecting the horse's fear of its own shadow, asked to tame the horse, which he eventually managed. Plutarch stated that Philip, overjoyed at this display of courage and ambition, kissed his son tearfully, declaring: "My boy, you must find a kingdom big enough for your ambitions. Macedon is too small for you", and bought the horse for him. Alexander named it Bucephalas, meaning "ox-head". Bucephalas | "Alexander the Great" | [
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3031 | carried Alexander as far as India. When the animal died (because of old age, according to Plutarch, at age thirty), Alexander named a city after him, Bucephala. When Alexander was 13, Philip began to search for a tutor, and considered such academics as Isocrates and Speusippus, the latter offering to resign from his stewardship of the Academy to take up the post. In the end, Philip chose Aristotle and provided the Temple of the Nymphs at Mieza as a classroom. In return for teaching Alexander, Philip agreed to rebuild Aristotle's hometown of Stageira, which Philip had razed, and to repopulate | "Alexander the Great" | [
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3032 | it by buying and freeing the ex-citizens who were slaves, or pardoning those who were in exile. Mieza was like a boarding school for Alexander and the children of Macedonian nobles, such as Ptolemy, Hephaistion, and Cassander. Many of these students would become his friends and future generals, and are often known as the 'Companions'. Aristotle taught Alexander and his companions about medicine, philosophy, morals, religion, logic, and art. Under Aristotle's tutelage, Alexander developed a passion for the works of Homer, and in particular the "Iliad"; Aristotle gave him an annotated copy, which Alexander later carried on his campaigns. At | "Alexander the Great" | [
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3033 | age 16, Alexander's education under Aristotle ended. Philip waged war against Byzantion, leaving Alexander in charge as regent and heir apparent. During Philip's absence, the Thracian Maedi revolted against Macedonia. Alexander responded quickly, driving them from their territory. He colonized it with Greeks, and founded a city named Alexandropolis. Upon Philip's return, he dispatched Alexander with a small force to subdue revolts in southern Thrace. Campaigning against the Greek city of Perinthus, Alexander is reported to have saved his father's life. Meanwhile, the city of Amphissa began to work lands that were sacred to Apollo near Delphi, a sacrilege that | "Alexander the Great" | [
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3034 | gave Philip the opportunity to further intervene in Greek affairs. Still occupied in Thrace, he ordered Alexander to muster an army for a campaign in southern Greece. Concerned that other Greek states might intervene, Alexander made it look as though he was preparing to attack Illyria instead. During this turmoil, the Illyrians invaded Macedonia, only to be repelled by Alexander. Philip and his army joined his son in 338 BC, and they marched south through Thermopylae, taking it after stubborn resistance from its Theban garrison. They went on to occupy the city of Elatea, only a few days' march from | "Alexander the Great" | [
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3035 | both Athens and Thebes. The Athenians, led by Demosthenes, voted to seek alliance with Thebes against Macedonia. Both Athens and Philip sent embassies to win Thebes' favour, but Athens won the contest. Philip marched on Amphissa (ostensibly acting on the request of the Amphictyonic League), capturing the mercenaries sent there by Demosthenes and accepting the city's surrender. Philip then returned to Elatea, sending a final offer of peace to Athens and Thebes, who both rejected it. As Philip marched south, his opponents blocked him near Chaeronea, Boeotia. During the ensuing Battle of Chaeronea, Philip commanded the right wing and Alexander | "Alexander the Great" | [
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3036 | the left, accompanied by a group of Philip's trusted generals. According to the ancient sources, the two sides fought bitterly for some time. Philip deliberately commanded his troops to retreat, counting on the untested Athenian hoplites to follow, thus breaking their line. Alexander was the first to break the Theban lines, followed by Philip's generals. Having damaged the enemy's cohesion, Philip ordered his troops to press forward and quickly routed them. With the Athenians lost, the Thebans were surrounded. Left to fight alone, they were defeated. After the victory at Chaeronea, Philip and Alexander marched unopposed into the Peloponnese, welcomed | "Alexander the Great" | [
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3037 | by all cities; however, when they reached Sparta, they were refused, but did not resort to war. At Corinth, Philip established a "Hellenic Alliance" (modelled on the old anti-Persian alliance of the Greco-Persian Wars), which included most Greek city-states except Sparta. Philip was then named "Hegemon" (often translated as "Supreme Commander") of this league (known by modern scholars as the League of Corinth), and announced his plans to attack the Persian Empire. When Philip returned to Pella, he fell in love with and married Cleopatra Eurydice in 338 BC, the niece of his general Attalus. The marriage made Alexander's position | "Alexander the Great" | [
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3038 | as heir less secure, since any son of Cleopatra Eurydice would be a fully Macedonian heir, while Alexander was only half-Macedonian. During the wedding banquet, a drunken Attalus publicly prayed to the gods that the union would produce a legitimate heir. Alexander fled Macedon with his mother, dropping her off with her brother, King Alexander I of Epirus in Dodona, capital of the Molossians. He continued to Illyria, where he sought refuge with the Illyrian king and was treated as a guest, despite having defeated them in battle a few years before. However, it appears Philip never intended to disown | "Alexander the Great" | [
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3039 | his politically and militarily trained son. Accordingly, Alexander returned to Macedon after six months due to the efforts of a family friend, Demaratus, who mediated between the two parties. In the following year, the Persian satrap (governor) of Caria, Pixodarus, offered his eldest daughter to Alexander's half-brother, Philip Arrhidaeus. Olympias and several of Alexander's friends suggested this showed Philip intended to make Arrhidaeus his heir. Alexander reacted by sending an actor, Thessalus of Corinth, to tell Pixodarus that he should not offer his daughter's hand to an illegitimate son, but instead to Alexander. When Philip heard of this, he stopped | "Alexander the Great" | [
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3040 | the negotiations and scolded Alexander for wishing to marry the daughter of a Carian, explaining that he wanted a better bride for him. Philip exiled four of Alexander's friends, Harpalus, Nearchus, Ptolemy and Erigyius, and had the Corinthians bring Thessalus to him in chains. In summer 336 BC, while at Aegae attending the wedding of his daughter Cleopatra to Olympias's brother, Alexander I of Epirus, Philip was assassinated by the captain of his bodyguards, Pausanias. As Pausanias tried to escape, he tripped over a vine and was killed by his pursuers, including two of Alexander's companions, Perdiccas and Leonnatus. Alexander | "Alexander the Great" | [
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3041 | was proclaimed king on the spot by the nobles and army at the age of 20. Alexander began his reign by eliminating potential rivals to the throne. He had his cousin, the former Amyntas IV, executed. He also had two Macedonian princes from the region of Lyncestis killed, but spared a third, Alexander Lyncestes. Olympias had Cleopatra Eurydice and Europa, her daughter by Philip, burned alive. When Alexander learned about this, he was furious. Alexander also ordered the murder of Attalus, who was in command of the advance guard of the army in Asia Minor and Cleopatra's uncle. Attalus was | "Alexander the Great" | [
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3042 | at that time corresponding with Demosthenes, regarding the possibility of defecting to Athens. Attalus also had severely insulted Alexander, and following Cleopatra's murder, Alexander may have considered him too dangerous to leave alive. Alexander spared Arrhidaeus, who was by all accounts mentally disabled, possibly as a result of poisoning by Olympias. News of Philip's death roused many states into revolt, including Thebes, Athens, Thessaly, and the Thracian tribes north of Macedon. When news of the revolts reached Alexander, he responded quickly. Though advised to use diplomacy, Alexander mustered 3,000 Macedonian cavalry and rode south towards Thessaly. He found the Thessalian | "Alexander the Great" | [
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3043 | army occupying the pass between Mount Olympus and Mount Ossa, and ordered his men to ride over Mount Ossa. When the Thessalians awoke the next day, they found Alexander in their rear and promptly surrendered, adding their cavalry to Alexander's force. He then continued south towards the Peloponnese. Alexander stopped at Thermopylae, where he was recognized as the leader of the Amphictyonic League before heading south to Corinth. Athens sued for peace and Alexander pardoned the rebels. The famous encounter between Alexander and Diogenes the Cynic occurred during Alexander's stay in Corinth. When Alexander asked Diogenes what he could do | "Alexander the Great" | [
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3044 | for him, the philosopher disdainfully asked Alexander to stand a little to the side, as he was blocking the sunlight. This reply apparently delighted Alexander, who is reported to have said "But verily, if I were not Alexander, I would like to be Diogenes." At Corinth, Alexander took the title of "Hegemon" ("leader") and, like Philip, was appointed commander for the coming war against Persia. He also received news of a Thracian uprising. Before crossing to Asia, Alexander wanted to safeguard his northern borders. In the spring of 335 BC, he advanced to suppress several revolts. Starting from Amphipolis, he | "Alexander the Great" | [
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3045 | travelled east into the country of the "Independent Thracians"; and at Mount Haemus, the Macedonian army attacked and defeated the Thracian forces manning the heights. The Macedonians marched into the country of the Triballi, and defeated their army near the Lyginus river (a tributary of the Danube). Alexander then marched for three days to the Danube, encountering the Getae tribe on the opposite shore. Crossing the river at night, he surprised them and forced their army to retreat after the first cavalry skirmish. News then reached Alexander that Cleitus, King of Illyria, and King Glaukias of the Taulantii were in | "Alexander the Great" | [
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3046 | open revolt against his authority. Marching west into Illyria, Alexander defeated each in turn, forcing the two rulers to flee with their troops. With these victories, he secured his northern frontier. While Alexander campaigned north, the Thebans and Athenians rebelled once again. Alexander immediately headed south. While the other cities again hesitated, Thebes decided to fight. The Theban resistance was ineffective, and Alexander razed the city and divided its territory between the other Boeotian cities. The end of Thebes cowed Athens, leaving all of Greece temporarily at peace. Alexander then set out on his Asian campaign, leaving Antipater as regent. | "Alexander the Great" | [
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3047 | Alexander's army crossed the Hellespont in 334 BC with approximately 48,100 soldiers, 6,100 cavalry and a fleet of 120 ships with crews numbering 38,000, drawn from Macedon and various Greek city-states, mercenaries, and feudally raised soldiers from Thrace, Paionia, and Illyria. He showed his intent to conquer the entirety of the Persian Empire by throwing a spear into Asian soil and saying he accepted Asia as a gift from the gods. This also showed Alexander's eagerness to fight, in contrast to his father's preference for diplomacy. After an initial victory against Persian forces at the Battle of the Granicus, Alexander | "Alexander the Great" | [
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3048 | accepted the surrender of the Persian provincial capital and treasury of Sardis; he then proceeded along the Ionian coast, granting autonomy and democracy to the cities. Miletus, held by Achaemenid forces, required a delicate siege operation, with Persian naval forces nearby. Further south, at Halicarnassus, in Caria, Alexander successfully waged his first large-scale siege, eventually forcing his opponents, the mercenary captain Memnon of Rhodes and the Persian satrap of Caria, Orontobates, to withdraw by sea. Alexander left the government of Caria to a member of the Hecatomnid dynasty, Ada, who adopted Alexander. From Halicarnassus, Alexander proceeded into mountainous Lycia and | "Alexander the Great" | [
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3049 | the Pamphylian plain, asserting control over all coastal cities to deny the Persians naval bases. From Pamphylia onwards the coast held no major ports and Alexander moved inland. At Termessos, Alexander humbled but did not storm the Pisidian city. At the ancient Phrygian capital of Gordium, Alexander "undid" the hitherto unsolvable Gordian Knot, a feat said to await the future "king of Asia". According to the story, Alexander proclaimed that it did not matter how the knot was undone and hacked it apart with his sword. In spring 333 BC, Alexander crossed the Taurus into Cilicia. After a long pause | "Alexander the Great" | [
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3050 | due to an illness, he marched on towards Syria. Though outmanoeuvered by Darius' significantly larger army, he marched back to Cilicia, where he defeated Darius at Issus. Darius fled the battle, causing his army to collapse, and left behind his wife, his two daughters, his mother Sisygambis, and a fabulous treasure. He offered a peace treaty that included the lands he had already lost, and a ransom of 10,000 talents for his family. Alexander replied that since he was now king of Asia, it was he alone who decided territorial divisions. Alexander proceeded to take possession of Syria, and most | "Alexander the Great" | [
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3051 | of the coast of the Levant. In the following year, 332 BC, he was forced to attack Tyre, which he captured after a long and difficult siege. The men of military age were massacred and the women and children sold into slavery. When Alexander destroyed Tyre, most of the towns on the route to Egypt quickly capitulated. However, Alexander met with resistance at Gaza. The stronghold was heavily fortified and built on a hill, requiring a siege. When "his engineers pointed out to him that because of the height of the mound it would be impossible... this encouraged Alexander all | "Alexander the Great" | [
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3052 | the more to make the attempt". After three unsuccessful assaults, the stronghold fell, but not before Alexander had received a serious shoulder wound. As in Tyre, men of military age were put to the sword and the women and children were sold into slavery. Alexander advanced on Egypt in later 332 BC, where he was regarded as a liberator. He was pronounced son of the deity Amun at the Oracle of Siwa Oasis in the Libyan desert. Henceforth, Alexander often referred to Zeus-Ammon as his true father, and after his death, currency depicted him adorned with the horns of a | "Alexander the Great" | [
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3053 | ram as a symbol of his divinity. During his stay in Egypt, he founded Alexandria-by-Egypt, which would become the prosperous capital of the Ptolemaic Kingdom after his death. Leaving Egypt in 331 BC, Alexander marched eastward into Mesopotamia (now northern Iraq) and again defeated Darius, at the Battle of Gaugamela. Darius once more fled the field, and Alexander chased him as far as Arbela. Gaugamela would be the final and decisive encounter between the two. Darius fled over the mountains to Ecbatana (modern Hamedan), while Alexander captured Babylon. From Babylon, Alexander went to Susa, one of the Achaemenid capitals, and | "Alexander the Great" | [
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3054 | captured its treasury. He sent the bulk of his army to the Persian ceremonial capital of Persepolis via the Persian Royal Road. Alexander himself took selected troops on the direct route to the city. He then stormed the pass of the Persian Gates (in the modern Zagros Mountains) which had been blocked by a Persian army under Ariobarzanes and then hurried to Persepolis before its garrison could loot the treasury. On entering Persepolis, Alexander allowed his troops to loot the city for several days. Alexander stayed in Persepolis for five months. During his stay a fire broke out in the | "Alexander the Great" | [
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3055 | eastern palace of Xerxes I and spread to the rest of the city. Possible causes include a drunken accident or deliberate revenge for the burning of the Acropolis of Athens during the Second Persian War by Xerxes. Even as he watched the city burn, Alexander immediately began to regret his decision. Plutarch claims that he ordered his men to put out the fires, but that the flames had already spread to most of the city. Curtius claims that Alexander did not regret his decision until the next morning. Plutarch recounts an anecdote in which Alexander pauses and talks to a | "Alexander the Great" | [
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3056 | fallen statue of Xerxes as if it were a live person: Alexander then chased Darius, first into Media, and then Parthia. The Persian king no longer controlled his own destiny, and was taken prisoner by Bessus, his Bactrian satrap and kinsman. As Alexander approached, Bessus had his men fatally stab the Great King and then declared himself Darius' successor as Artaxerxes V, before retreating into Central Asia to launch a guerrilla campaign against Alexander. Alexander buried Darius' remains next to his Achaemenid predecessors in a regal funeral. He claimed that, while dying, Darius had named him as his successor to | "Alexander the Great" | [
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3057 | the Achaemenid throne. The Achaemenid Empire is normally considered to have fallen with Darius. Alexander viewed Bessus as a usurper and set out to defeat him. This campaign, initially against Bessus, turned into a grand tour of central Asia. Alexander founded a series of new cities, all called Alexandria, including modern Kandahar in Afghanistan, and Alexandria Eschate ("The Furthest") in modern Tajikistan. The campaign took Alexander through Media, Parthia, Aria (West Afghanistan), Drangiana, Arachosia (South and Central Afghanistan), Bactria (North and Central Afghanistan), and Scythia. Spitamenes, who held an undefined position in the satrapy of Sogdiana, in 329 BC betrayed | "Alexander the Great" | [
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3058 | Bessus to Ptolemy, one of Alexander's trusted companions, and Bessus was executed. However, when, at some point later, Alexander was on the Jaxartes dealing with an incursion by a horse nomad army, Spitamenes raised Sogdiana in revolt. Alexander personally defeated the Scythians at the Battle of Jaxartes and immediately launched a campaign against Spitamenes, defeating him in the Battle of Gabai. After the defeat, Spitamenes was killed by his own men, who then sued for peace. During this time, Alexander adopted some elements of Persian dress and customs at his court, notably the custom of "proskynesis", either a symbolic kissing | "Alexander the Great" | [
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3059 | of the hand, or prostration on the ground, that Persians showed to their social superiors. The Greeks regarded the gesture as the province of deities and believed that Alexander meant to deify himself by requiring it. This cost him the sympathies of many of his countrymen, and he eventually abandoned it. A plot against his life was revealed, and one of his officers, Philotas, was executed for failing to alert Alexander. The death of the son necessitated the death of the father, and thus Parmenion, who had been charged with guarding the treasury at Ecbatana, was assassinated at Alexander's command, | "Alexander the Great" | [
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3060 | to prevent attempts at vengeance. Most infamously, Alexander personally killed the man who had saved his life at Granicus, Cleitus the Black, during a violent drunken altercation at Maracanda (modern day Samarkand in Uzbekistan), in which Cleitus accused Alexander of several judgmental mistakes and most especially, of having forgotten the Macedonian ways in favour of a corrupt oriental lifestyle. Later, in the Central Asian campaign, a second plot against his life was revealed, this one instigated by his own royal pages. His official historian, Callisthenes of Olynthus, was implicated in the plot, and in the "Anabasis of Alexander", Arrian states | "Alexander the Great" | [
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3061 | that Callisthenes and the pages were then tortured on the rack as punishment, and likely died soon after. It remains unclear if Callisthenes was actually involved in the plot, for prior to his accusation he had fallen out of favour by leading the opposition to the attempt to introduce proskynesis. When Alexander set out for Asia, he left his general Antipater, an experienced military and political leader and part of Philip II's "Old Guard", in charge of Macedon. Alexander's sacking of Thebes ensured that Greece remained quiet during his absence. The one exception was a call to arms by Spartan | "Alexander the Great" | [
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3062 | king Agis III in 331 BC, whom Antipater defeated and killed in the battle of Megalopolis. Antipater referred the Spartans' punishment to the League of Corinth, which then deferred to Alexander, who chose to pardon them. There was also considerable friction between Antipater and Olympias, and each complained to Alexander about the other. In general, Greece enjoyed a period of peace and prosperity during Alexander's campaign in Asia. Alexander sent back vast sums from his conquest, which stimulated the economy and increased trade across his empire. However, Alexander's constant demands for troops and the migration of Macedonians throughout his empire | "Alexander the Great" | [
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3063 | depleted Macedon's strength, greatly weakening it in the years after Alexander, and ultimately led to its subjugation by Rome after the Third Macedonian War (171–168 BC). After the death of Spitamenes and his marriage to Roxana (Raoxshna in Old Iranian) to cement relations with his new satrapies, Alexander turned to the Indian subcontinent. He invited the chieftains of the former satrapy of Gandhara (a region presently straddling eastern Afghanistan and northern Pakistan), to come to him and submit to his authority. Omphis (Indian name Ambhi), the ruler of Taxila, whose kingdom extended from the Indus to the Hydaspes (Jhelum), complied, | "Alexander the Great" | [
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3064 | but the chieftains of some hill clans, including the Aspasioi and Assakenoi sections of the Kambojas (known in Indian texts also as Ashvayanas and Ashvakayanas), refused to submit. Ambhi hastened to relieve Alexander of his apprehension and met him with valuable presents, placing himself and all his forces at his disposal. Alexander not only returned Ambhi his title and the gifts but he also presented him with a wardrobe of "Persian robes, gold and silver ornaments, 30 horses and 1,000 talents in gold". Alexander was emboldened to divide his forces, and Ambhi assisted Hephaestion and Perdiccas in constructing a bridge | "Alexander the Great" | [
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3065 | over the Indus where it bends at Hund (Fox 1973), supplied their troops with provisions, and received Alexander himself, and his whole army, in his capital city of Taxila, with every demonstration of friendship and the most liberal hospitality. On the subsequent advance of the Macedonian king, Taxiles accompanied him with a force of 5,000 men and took part in the battle of the Hydaspes River. After that victory he was sent by Alexander in pursuit of Porus, to whom he was charged to offer favourable terms, but narrowly escaped losing his life at the hands of his old enemy. | "Alexander the Great" | [
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3066 | Subsequently, however, the two rivals were reconciled by the personal mediation of Alexander; and Taxiles, after having contributed zealously to the equipment of the fleet on the Hydaspes, was entrusted by the king with the government of the whole territory between that river and the Indus. A considerable accession of power was granted him after the death of Philip, son of Machatas; and he was allowed to retain his authority at the death of Alexander himself (323 BC), as well as in the subsequent partition of the provinces at Triparadisus, 321 BC. In the winter of 327/326 BC, Alexander personally | "Alexander the Great" | [
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3067 | led a campaign against the Aspasioi of Kunar valleys, the Guraeans of the Guraeus valley, and the Assakenoi of the Swat and Buner valleys. A fierce contest ensued with the Aspasioi in which Alexander was wounded in the shoulder by a dart, but eventually the Aspasioi lost. Alexander then faced the Assakenoi, who fought against him from the strongholds of Massaga, Ora and Aornos. The fort of Massaga was reduced only after days of bloody fighting, in which Alexander was wounded seriously in the ankle. According to Curtius, "Not only did Alexander slaughter the entire population of Massaga, but also | "Alexander the Great" | [
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3068 | did he reduce its buildings to rubble." A similar slaughter followed at Ora. In the aftermath of Massaga and Ora, numerous Assakenians fled to the fortress of Aornos. Alexander followed close behind and captured the strategic hill-fort after four bloody days. After Aornos, Alexander crossed the Indus and fought and won an epic battle against King Porus, who ruled a region lying between the Hydaspes and the Acesines (Chenab), in what is now the Punjab, in the Battle of the Hydaspes in 326 BC. Alexander was impressed by Porus' bravery, and made him an ally. He appointed Porus as satrap, | "Alexander the Great" | [
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3069 | and added to Porus' territory land that he did not previously own, towards the south-east, up to the Hyphasis (Beas). Choosing a local helped him control these lands so distant from Greece. Alexander founded two cities on opposite sides of the Hydaspes river, naming one Bucephala, in honour of his horse, who died around this time. The other was Nicaea (Victory), thought to be located at the site of modern-day Mong, Punjab. East of Porus' kingdom, near the Ganges River, was the Nanda Empire of Magadha, and further east, the Gangaridai Empire of Bengal region of the Indian subcontinent. Fearing | "Alexander the Great" | [
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3070 | the prospect of facing other large armies and exhausted by years of campaigning, Alexander's army mutinied at the Hyphasis River (Beas), refusing to march farther east. This river thus marks the easternmost extent of Alexander's conquests. Alexander tried to persuade his soldiers to march farther, but his general Coenus pleaded with him to change his opinion and return; the men, he said, "longed to again see their parents, their wives and children, their homeland". Alexander eventually agreed and turned south, marching along the Indus. Along the way his army conquered the Malhi (in modern-day Multan) and other Indian tribes and | "Alexander the Great" | [
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3071 | Alexander sustained an injury during the siege. Alexander sent much of his army to Carmania (modern southern Iran) with general Craterus, and commissioned a fleet to explore the Persian Gulf shore under his admiral Nearchus, while he led the rest back to Persia through the more difficult southern route along the Gedrosian Desert and Makran. Alexander reached Susa in 324 BC, but not before losing many men to the harsh desert. Discovering that many of his satraps and military governors had misbehaved in his absence, Alexander executed several of them as examples on his way to Susa. As a gesture | "Alexander the Great" | [
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3072 | of thanks, he paid off the debts of his soldiers, and announced that he would send over-aged and disabled veterans back to Macedon, led by Craterus. His troops misunderstood his intention and mutinied at the town of Opis. They refused to be sent away and criticized his adoption of Persian customs and dress and the introduction of Persian officers and soldiers into Macedonian units. After three days, unable to persuade his men to back down, Alexander gave Persians command posts in the army and conferred Macedonian military titles upon Persian units. The Macedonians quickly begged forgiveness, which Alexander accepted, and | "Alexander the Great" | [
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3073 | held a great banquet for several thousand of his men at which he and they ate together. In an attempt to craft a lasting harmony between his Macedonian and Persian subjects, Alexander held a mass marriage of his senior officers to Persian and other noblewomen at Susa, but few of those marriages seem to have lasted much beyond a year. Meanwhile, upon his return to Persia, Alexander learned that guards of the tomb of Cyrus the Great in Pasargadae had desecrated it, and swiftly executed them. Alexander admired Cyrus the Great, from an early age reading Xenophon's "Cyropaedia", which described | "Alexander the Great" | [
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3074 | Cyrus's heroism in battle and governance as a king and legislator. During his visit to Pasargadae Alexander ordered his architect Aristobulus to decorate the interior of the sepulchral chamber of Cyrus' tomb. Afterwards, Alexander travelled to Ecbatana to retrieve the bulk of the Persian treasure. There, his closest friend and possible lover, Hephaestion, died of illness or poisoning. Hephaestion's death devastated Alexander, and he ordered the preparation of an expensive funeral pyre in Babylon, as well as a decree for public mourning. Back in Babylon, Alexander planned a series of new campaigns, beginning with an invasion of Arabia, but he | "Alexander the Great" | [
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3075 | would not have a chance to realize them, as he died shortly after Hephaestion. On either 10 or 11 June 323 BC, Alexander died in the palace of Nebuchadnezzar II, in Babylon, at age 32. There are two different versions of Alexander's death and details of the death differ slightly in each. Plutarch's account is that roughly 14 days before his death, Alexander entertained admiral Nearchus, and spent the night and next day drinking with Medius of Larissa. He developed a fever, which worsened until he was unable to speak. The common soldiers, anxious about his health, were granted the | "Alexander the Great" | [
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3076 | right to file past him as he silently waved at them. In the second account, Diodorus recounts that Alexander was struck with pain after downing a large bowl of unmixed wine in honour of Heracles, followed by 11 days of weakness; he did not develop a fever and died after some agony. Arrian also mentioned this as an alternative, but Plutarch specifically denied this claim. Given the propensity of the Macedonian aristocracy to assassination, foul play featured in multiple accounts of his death. Diodorus, Plutarch, Arrian and Justin all mentioned the theory that Alexander was poisoned. Justin stated that Alexander | "Alexander the Great" | [
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3077 | was the victim of a poisoning conspiracy, Plutarch dismissed it as a fabrication, while both Diodorus and Arrian noted that they mentioned it only for the sake of completeness. The accounts were nevertheless fairly consistent in designating Antipater, recently removed as Macedonian viceroy, and at odds with Olympias, as the head of the alleged plot. Perhaps taking his summons to Babylon as a death sentence, and having seen the fate of Parmenion and Philotas, Antipater purportedly arranged for Alexander to be poisoned by his son Iollas, who was Alexander's wine-pourer. There was even a suggestion that Aristotle may have participated. | "Alexander the Great" | [
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3078 | The strongest argument against the poison theory is the fact that twelve days passed between the start of his illness and his death; such long-acting poisons were probably not available. However, in a 2003 BBC documentary investigating the death of Alexander, Leo Schep from the New Zealand National Poisons Centre proposed that the plant white hellebore ("Veratrum album"), which was known in antiquity, may have been used to poison Alexander. In a 2014 manuscript in the journal Clinical Toxicology, Schep suggested Alexander's wine was spiked with "Veratrum album", and that this would produce poisoning symptoms that match the course of | "Alexander the Great" | [
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3079 | events described in the "Alexander Romance". "Veratrum album" poisoning can have a prolonged course and it was suggested that if Alexander was poisoned, "Veratrum album" offers the most plausible cause. Another poisoning explanation put forward in 2010 proposed that the circumstances of his death were compatible with poisoning by water of the river Styx (modern-day Mavroneri in Arcadia, Greece) that contained calicheamicin, a dangerous compound produced by bacteria. Several natural causes (diseases) have been suggested, including malaria and typhoid fever. A 1998 article in the "New England Journal of Medicine" attributed his death to typhoid fever complicated by bowel perforation | "Alexander the Great" | [
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3080 | and ascending paralysis. Another recent analysis suggested pyogenic (infectious) spondylitis or meningitis. Other illnesses fit the symptoms, including acute pancreatitis and West Nile virus. Natural-cause theories also tend to emphasize that Alexander's health may have been in general decline after years of heavy drinking and severe wounds. The anguish that Alexander felt after Hephaestion's death may also have contributed to his declining health. Alexander's body was laid in a gold anthropoid sarcophagus that was filled with honey, which was in turn placed in a gold casket. According to Aelian, a seer called Aristander foretold that the land where Alexander was | "Alexander the Great" | [
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3081 | laid to rest "would be happy and unvanquishable forever". Perhaps more likely, the successors may have seen possession of the body as a symbol of legitimacy, since burying the prior king was a royal prerogative. While Alexander's funeral cortege was on its way to Macedon, Ptolemy seized it and took it temporarily to Memphis. His successor, Ptolemy II Philadelphus, transferred the sarcophagus to Alexandria, where it remained until at least late Antiquity. Ptolemy IX Lathyros, one of Ptolemy's final successors, replaced Alexander's sarcophagus with a glass one so he could convert the original to coinage. The recent discovery of an | "Alexander the Great" | [
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3082 | enormous tomb in northern Greece, at Amphipolis, dating from the time of Alexander the Great has given rise to speculation that its original intent was to be the burial place of Alexander. This would fit with the intended destination of Alexander's funeral cortege. Pompey, Julius Caesar and Augustus all visited the tomb in Alexandria, where Augustus, allegedly, accidentally knocked the nose off. Caligula was said to have taken Alexander's breastplate from the tomb for his own use. Around AD 200, Emperor Septimius Severus closed Alexander's tomb to the public. His son and successor, Caracalla, a great admirer, visited the tomb | "Alexander the Great" | [
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3083 | during his own reign. After this, details on the fate of the tomb are hazy. The so-called "Alexander Sarcophagus", discovered near Sidon and now in the Istanbul Archaeology Museum, is so named not because it was thought to have contained Alexander's remains, but because its bas-reliefs depict Alexander and his companions fighting the Persians and hunting. It was originally thought to have been the sarcophagus of Abdalonymus (died 311 BC), the king of Sidon appointed by Alexander immediately following the battle of Issus in 331. However, more recently, it has been suggested that it may date from earlier than Abdalonymus' | "Alexander the Great" | [
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3084 | death. Alexander's death was so sudden that when reports of his death reached Greece, they were not immediately believed. Alexander had no obvious or legitimate heir, his son Alexander IV by Roxane being born after Alexander's death. According to Diodorus, Alexander's companions asked him on his deathbed to whom he bequeathed his kingdom; his laconic reply was "tôi kratistôi"—"to the strongest". Another theory is that his successors willfully or erroneously misheard "tôi Kraterôi"—"to Craterus", the general leading his Macedonian troops home and newly entrusted with the regency of Macedonia. Arrian and Plutarch claimed that Alexander was speechless by this point, | "Alexander the Great" | [
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3085 | implying that this was an apocryphal story. Diodorus, Curtius and Justin offered the more plausible story that Alexander passed his signet ring to Perdiccas, a bodyguard and leader of the companion cavalry, in front of witnesses, thereby nominating him. Perdiccas initially did not claim power, instead suggesting that Roxane's baby would be king, if male; with himself, Craterus, Leonnatus, and Antipater as guardians. However, the infantry, under the command of Meleager, rejected this arrangement since they had been excluded from the discussion. Instead, they supported Alexander's half-brother Philip Arrhidaeus. Eventually, the two sides reconciled, and after the birth of Alexander | "Alexander the Great" | [
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3086 | IV, he and Philip III were appointed joint kings, albeit in name only. Dissension and rivalry soon afflicted the Macedonians, however. The satrapies handed out by Perdiccas at the Partition of Babylon became power bases each general used to bid for power. After the assassination of Perdiccas in 321 BC, Macedonian unity collapsed, and 40 years of war between "The Successors" ("Diadochi") ensued before the Hellenistic world settled into four stable power blocs: Ptolemaic Egypt, Seleucid Mesopotamia and Central Asia, Attalid Anatolia, and Antigonid Macedon. In the process, both Alexander IV and Philip III were murdered. Diodorus stated that Alexander | "Alexander the Great" | [
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3087 | had given detailed written instructions to Craterus some time before his death. Craterus started to carry out Alexander's commands, but the successors chose not to further implement them, on the grounds they were impractical and extravagant. Nevertheless, Perdiccas read Alexander's will to his troops. Alexander's will called for military expansion into the southern and western Mediterranean, monumental constructions, and the intermixing of Eastern and Western populations. It included: Alexander earned the epithet "the Great" due to his unparalleled success as a military commander. He never lost a battle, despite typically being outnumbered. This was due to use of terrain, phalanx | "Alexander the Great" | [
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3088 | and cavalry tactics, bold strategy, and the fierce loyalty of his troops. The Macedonian phalanx, armed with the sarissa, a spear long, had been developed and perfected by Philip II through rigorous training, and Alexander used its speed and maneuverability to great effect against larger but more disparate Persian forces. Alexander also recognized the potential for disunity among his diverse army, which employed various languages and weapons. He overcame this by being personally involved in battle, in the manner of a Macedonian king. In his first battle in Asia, at Granicus, Alexander used only a small part of his forces, | "Alexander the Great" | [
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3089 | perhaps 13,000 infantry with 5,000 cavalry, against a much larger Persian force of 40,000. Alexander placed the phalanx at the center and cavalry and archers on the wings, so that his line matched the length of the Persian cavalry line, about . By contrast, the Persian infantry was stationed behind its cavalry. This ensured that Alexander would not be outflanked, while his phalanx, armed with long pikes, had a considerable advantage over the Persians' scimitars and javelins. Macedonian losses were negligible compared to those of the Persians. At Issus in 333 BC, his first confrontation with Darius, he used the | "Alexander the Great" | [
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3090 | same deployment, and again the central phalanx pushed through. Alexander personally led the charge in the center, routing the opposing army. At the decisive encounter with Darius at Gaugamela, Darius equipped his chariots with scythes on the wheels to break up the phalanx and equipped his cavalry with pikes. Alexander arranged a double phalanx, with the center advancing at an angle, parting when the chariots bore down and then reforming. The advance was successful and broke Darius' center, causing the latter to flee once again. When faced with opponents who used unfamiliar fighting techniques, such as in Central Asia and | "Alexander the Great" | [
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3091 | India, Alexander adapted his forces to his opponents' style. Thus, in Bactria and Sogdiana, Alexander successfully used his javelin throwers and archers to prevent outflanking movements, while massing his cavalry at the center. In India, confronted by Porus' elephant corps, the Macedonians opened their ranks to envelop the elephants and used their sarissas to strike upwards and dislodge the elephants' handlers. Greek biographer Plutarch () describes Alexander's appearance as: Greek historian Arrian (Lucius Flavius Arrianus 'Xenophon' ) described Alexander as: The semi-legendary "Alexander Romance" also suggests that Alexander exhibited heterochromia iridum: that one eye was dark and the other light. | "Alexander the Great" | [
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3092 | British historian Peter Green provided a description of Alexander's appearance, based on his review of statues and some ancient documents: Ancient authors recorded that Alexander was so pleased with portraits of himself created by Lysippos that he forbade other sculptors from crafting his image. Lysippos had often used the contrapposto sculptural scheme to portray Alexander and other characters such as Apoxyomenos, Hermes and Eros. Lysippos' sculpture, famous for its naturalism, as opposed to a stiffer, more static pose, is thought to be the most faithful depiction. Some of Alexander's strongest personality traits formed in response to his parents. His mother | "Alexander the Great" | [
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3093 | had huge ambitions, and encouraged him to believe it was his destiny to conquer the Persian Empire. Olympias' influence instilled a sense of destiny in him, and Plutarch tells how his ambition "kept his spirit serious and lofty in advance of his years". However, his father Philip was Alexander's most immediate and influential role model, as the young Alexander watched him campaign practically every year, winning victory after victory while ignoring severe wounds. Alexander's relationship with his father forged the competitive side of his personality; he had a need to outdo his father, illustrated by his reckless behaviour in battle. | "Alexander the Great" | [
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3094 | While Alexander worried that his father would leave him "no great or brilliant achievement to be displayed to the world", he also downplayed his father's achievements to his companions. According to Plutarch, among Alexander's traits were a violent temper and rash, impulsive nature, which undoubtedly contributed to some of his decisions. Although Alexander was stubborn and did not respond well to orders from his father, he was open to reasoned debate. He had a calmer side—perceptive, logical, and calculating. He had a great desire for knowledge, a love for philosophy, and was an avid reader. This was no doubt in | "Alexander the Great" | [
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3095 | part due to Aristotle's tutelage; Alexander was intelligent and quick to learn. His intelligent and rational side was amply demonstrated by his ability and success as a general. He had great self-restraint in "pleasures of the body", in contrast with his lack of self-control with alcohol. Alexander was erudite and patronized both arts and sciences. However, he had little interest in sports or the Olympic games (unlike his father), seeking only the Homeric ideals of honour ("timê") and glory ("kudos"). He had great charisma and force of personality, characteristics which made him a great leader. His unique abilities were further | "Alexander the Great" | [
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3096 | demonstrated by the inability of any of his generals to unite Macedonia and retain the Empire after his death—only Alexander had the ability to do so. During his final years, and especially after the death of Hephaestion, Alexander began to exhibit signs of megalomania and paranoia. His extraordinary achievements, coupled with his own ineffable sense of destiny and the flattery of his companions, may have combined to produce this effect. His delusions of grandeur are readily visible in his will and in his desire to conquer the world, in as much as he is by various sources described as having | "Alexander the Great" | [
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3097 | "boundless ambition", an epithet, the meaning of which has descended into an historical cliché. He appears to have believed himself a deity, or at least sought to deify himself. Olympias always insisted to him that he was the son of Zeus, a theory apparently confirmed to him by the oracle of Amun at Siwa. He began to identify himself as the son of Zeus-Ammon. Alexander adopted elements of Persian dress and customs at court, notably "proskynesis", a practice of which Macedonians disapproved, and were loath to perform. This behaviour cost him the sympathies of many of his countrymen. However, Alexander | "Alexander the Great" | [
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3098 | also was a pragmatic ruler who understood the difficulties of ruling culturally disparate peoples, many of whom lived in kingdoms where the king was divine. Thus, rather than megalomania, his behaviour may simply have been a practical attempt at strengthening his rule and keeping his empire together. Alexander married three times: Roxana, daughter of the Sogdian nobleman Oxyartes of Bactria, out of love; and the Persian princesses Stateira II and Parysatis II, the former a daughter of Darius III and latter a daughter of Artaxerxes III, for political reasons. He apparently had two sons, Alexander IV of Macedon by Roxana | "Alexander the Great" | [
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3099 | and, possibly, Heracles of Macedon from his mistress Barsine. He lost another child when Roxana miscarried at Babylon. Alexander also had a close relationship with his friend, general, and bodyguard Hephaestion, the son of a Macedonian noble. Hephaestion's death devastated Alexander. This event may have contributed to Alexander's failing health and detached mental state during his final months. Alexander's sexuality has been the subject of speculation and controversy. No ancient sources stated that Alexander had homosexual relationships, or that Alexander's relationship with Hephaestion was sexual. Aelian, however, writes of Alexander's visit to Troy where "Alexander garlanded the tomb of Achilles, | "Alexander the Great" | [
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3100 | and Hephaestion that of Patroclus, the latter hinting that he was a beloved of Alexander, in just the same way as Patroclus was of Achilles." Noting that the word "eromenos" (ancient Greek for beloved) does not necessarily bear sexual meaning. Alexander may have been bisexual, in keeping with Greek upper class custom. Green argues that there is little evidence in ancient sources that Alexander had much carnal interest in women; he did not produce an heir until the very end of his life. However, he was relatively young when he died, and Ogden suggests that Alexander's matrimonial record is more | "Alexander the Great" | [
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0.04271303862333298,
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0.00338510749861598,
-0.08039207756519318,
-0.1644955724477768,
-0.10619090497493744,
0.382406920... |
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