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34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | Hyperoxia in pediatric severe traumatic brain injury (TBI): a comparison of patient classification by cutoff versus cumulative (area-under-the-curve) analysis. | ## OBJECTIVE
Hyperoxia is associated with adverse outcome in severe traumatic brain injury (TBI). This study explored differences in patient classification of oxygen exposure by PaO
## METHODS
Retrospective, explorative study including children (<18 years) with accidental severe TBI (2002-2015). Oxygen exposure analysi... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | Incidence of hyperoxia and related in-hospital mortality in critically ill patients: a retrospective data analysis. | ## BACKGROUND
Mechanical ventilation with oxygen is life-saving, however, may result in hyperoxia. The aim was to analyse the incidence and duration of hyperoxia burden and related in-hospital mortality in critically ill patients.
## METHODS
Patients of all ages admitted to intensive care units (ICUs) and with mechanic... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | Post return of spontaneous circulation factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study. | ## INTRODUCTION
Most studies have analyzed pre-arrest and resuscitation factors associated with mortality after cardiac arrest (CA) in children, but many patients that reach return of spontaneous circulation die within the next days or weeks. The objective of our study was to analyze post-return of spontaneous circulat... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | Admission Hyperoxia Is a Risk Factor for Mortality in Pediatric Intensive Care. | ## OBJECTIVES
To determine whether the association between hyperoxia and increased risk-adjusted mortality in adult intensive care patients is also observed in a pediatric intensive care population.
## DESIGN
Single-center retrospective analysis of admissions to ICU over a 5-year period commencing January 1, 2012, exam... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | Maximum Pao2 in the First 72 Hours of Intensive Care Is Associated With Risk-Adjusted Mortality in Pediatric Patients Undergoing Mechanical Ventilation. | A relationship between Pao2 and mortality has previously been observed in single-center studies. We performed a retrospective cohort study of the Pediatric Health Information System plus database including patients less than or equal to 21 years old admitted to a medical or cardiac ICU who received invasive ventilation... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial. | ## BACKGROUND
Oxygen saturation monitoring for children receiving respiratory support is standard worldwide. No randomised clinical trials have compared peripheral oxygen saturation (SpO
## METHODS
We undertook an open, parallel-group randomised trial of children > 38 weeks completed gestation and < 16 years of age rec... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | Admission PaO2 and Mortality in Critically Ill Children: A Cohort Study and Systematic Review. | ## OBJECTIVE
To describe the relationship between PaO2 at intensive care admission and mortality in critically ill children and to review systematically the literature describing this relationship.
## DESIGN
Cohort study: A review of consecutive tertiary pediatric intensive care admissions (January 2004 to December 201... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a Pediatric Intensive Care Unit. | ## IMPORTANCE
A high Pao2, termed hyperoxemia, is postulated to have deleterious health outcomes. To date, the association between hyperoxemia during the ongoing management of critical illness and mortality has been incompletely evaluated in children.
## OBJECTIVE
To examine whether severe hyperoxemia events are associ... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | Early Hyperoxemia and Outcome Among Critically Ill Children. | ## OBJECTIVE
To identify whether a high PaO2 (hyperoxemia) at the time of presentation to the PICU is associated with in-hospital mortality.
## DESIGN
Single-center observational study.
## SETTING
Quaternary-care PICU.
## PATIENTS
Encounters admitted between January 1, 2009, and December 31, 2018.
## INTERVENTIONS
None... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | Hyperoxia Is Associated With Poor Outcomes in Pediatric Cardiac Patients Supported on Venoarterial Extracorporeal Membrane Oxygenation. | ## OBJECTIVES
Patients who require venoarterial extracorporeal membrane oxygenation because of cardiac failure frequently have supranormal blood oxygen tensions (hyperoxia). Recent studies have suggested worse outcomes in patients with hyperoxia after resuscitation from cardiac or respiratory arrests, presumably becaus... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Case Mix - General | High cumulative oxygen levels are associated with improved survival of children treated with mild therapeutic hypothermia after cardiac arrest. | ## AIM
The aim of this study was to analyze the relationship between the partial pressure of arterial oxygen (PaO2) and in-hospital (IH) mortality in children after cardiac arrest (CA) using the conventional cutoff analysis, which was compared with the cumulative analysis, a new method in PaO2 analysis. Additionally, w... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Early oxygenation and ventilation measurements after pediatric cardiac arrest: lack of association with outcome. | ## OBJECTIVES
To explore oxygenation and ventilation status early after cardiac arrest in infants and children. We hypothesize that hyperoxia is common and associated with worse outcome after pediatric cardiac arrest.
## DESIGN
Retrospective cohort study.
## SETTING
Fifteen hospitals within the Pediatric Emergency Care... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Hyperoxia and Hypocapnia During Pediatric Extracorporeal Membrane Oxygenation: Associations With Complications, Mortality, and Functional Status Among Survivors. | ## OBJECTIVES
To determine the frequency of hyperoxia and hypocapnia during pediatric extracorporeal membrane oxygenation and their relationships to complications, mortality, and functional status among survivors.
## DESIGN
Secondary analysis of data collected prospectively by the Collaborative Pediatric Critical Care ... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Hyperoxia, hypocapnia and hypercapnia as outcome factors after cardiac arrest in children. | ## PURPOSE
Arterial hyperoxia after resuscitation has been associated with increased mortality in adults. The aim of this study was to test the hypothesis that post-resuscitation hyperoxia and hypocapnia are associated with increased mortality after resuscitation in pediatric patients.
## METHODS
We performed a prospec... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Relationship between arterial partial oxygen pressure after resuscitation from cardiac arrest and mortality in children. | ## BACKGROUND
Observational studies in adults have shown a worse outcome associated with hyperoxia after resuscitation from cardiac arrest. Extrapolating from adult data, current pediatric resuscitation guidelines recommend avoiding hyperoxia. We investigated the relationship between arterial partial oxygen pressure an... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Hyperoxia and hypoxia in children resuscitated from cardiac arrest. | ## BACKGROUND
Ischemia depletes antioxidant reserves and impairs mitochondrial electron transport. Oxygen within blood reperfusing ischemic tissue can form free radicals, worsen oxidative stress, and exacerbate tissue injury (reperfusion injury). One strategy for limiting reperfusion injury is to limit delivery of "lux... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Hyperoxia in pediatric severe traumatic brain injury (TBI): a comparison of patient classification by cutoff versus cumulative (area-under-the-curve) analysis. | ## OBJECTIVE
Hyperoxia is associated with adverse outcome in severe traumatic brain injury (TBI). This study explored differences in patient classification of oxygen exposure by PaO
## METHODS
Retrospective, explorative study including children (<18 years) with accidental severe TBI (2002-2015). Oxygen exposure analysi... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Incidence of hyperoxia and related in-hospital mortality in critically ill patients: a retrospective data analysis. | ## BACKGROUND
Mechanical ventilation with oxygen is life-saving, however, may result in hyperoxia. The aim was to analyse the incidence and duration of hyperoxia burden and related in-hospital mortality in critically ill patients.
## METHODS
Patients of all ages admitted to intensive care units (ICUs) and with mechanic... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Post return of spontaneous circulation factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study. | ## INTRODUCTION
Most studies have analyzed pre-arrest and resuscitation factors associated with mortality after cardiac arrest (CA) in children, but many patients that reach return of spontaneous circulation die within the next days or weeks. The objective of our study was to analyze post-return of spontaneous circulat... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Admission Hyperoxia Is a Risk Factor for Mortality in Pediatric Intensive Care. | ## OBJECTIVES
To determine whether the association between hyperoxia and increased risk-adjusted mortality in adult intensive care patients is also observed in a pediatric intensive care population.
## DESIGN
Single-center retrospective analysis of admissions to ICU over a 5-year period commencing January 1, 2012, exam... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Maximum Pao2 in the First 72 Hours of Intensive Care Is Associated With Risk-Adjusted Mortality in Pediatric Patients Undergoing Mechanical Ventilation. | A relationship between Pao2 and mortality has previously been observed in single-center studies. We performed a retrospective cohort study of the Pediatric Health Information System plus database including patients less than or equal to 21 years old admitted to a medical or cardiac ICU who received invasive ventilation... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial. | ## BACKGROUND
Oxygen saturation monitoring for children receiving respiratory support is standard worldwide. No randomised clinical trials have compared peripheral oxygen saturation (SpO
## METHODS
We undertook an open, parallel-group randomised trial of children > 38 weeks completed gestation and < 16 years of age rec... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Admission PaO2 and Mortality in Critically Ill Children: A Cohort Study and Systematic Review. | ## OBJECTIVE
To describe the relationship between PaO2 at intensive care admission and mortality in critically ill children and to review systematically the literature describing this relationship.
## DESIGN
Cohort study: A review of consecutive tertiary pediatric intensive care admissions (January 2004 to December 201... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a Pediatric Intensive Care Unit. | ## IMPORTANCE
A high Pao2, termed hyperoxemia, is postulated to have deleterious health outcomes. To date, the association between hyperoxemia during the ongoing management of critical illness and mortality has been incompletely evaluated in children.
## OBJECTIVE
To examine whether severe hyperoxemia events are associ... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Early Hyperoxemia and Outcome Among Critically Ill Children. | ## OBJECTIVE
To identify whether a high PaO2 (hyperoxemia) at the time of presentation to the PICU is associated with in-hospital mortality.
## DESIGN
Single-center observational study.
## SETTING
Quaternary-care PICU.
## PATIENTS
Encounters admitted between January 1, 2009, and December 31, 2018.
## INTERVENTIONS
None... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | Hyperoxia Is Associated With Poor Outcomes in Pediatric Cardiac Patients Supported on Venoarterial Extracorporeal Membrane Oxygenation. | ## OBJECTIVES
Patients who require venoarterial extracorporeal membrane oxygenation because of cardiac failure frequently have supranormal blood oxygen tensions (hyperoxia). Recent studies have suggested worse outcomes in patients with hyperoxia after resuscitation from cardiac or respiratory arrests, presumably becaus... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >200 mm Hg (27 kPa) | High cumulative oxygen levels are associated with improved survival of children treated with mild therapeutic hypothermia after cardiac arrest. | ## AIM
The aim of this study was to analyze the relationship between the partial pressure of arterial oxygen (PaO2) and in-hospital (IH) mortality in children after cardiac arrest (CA) using the conventional cutoff analysis, which was compared with the cumulative analysis, a new method in PaO2 analysis. Additionally, w... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Early oxygenation and ventilation measurements after pediatric cardiac arrest: lack of association with outcome. | ## OBJECTIVES
To explore oxygenation and ventilation status early after cardiac arrest in infants and children. We hypothesize that hyperoxia is common and associated with worse outcome after pediatric cardiac arrest.
## DESIGN
Retrospective cohort study.
## SETTING
Fifteen hospitals within the Pediatric Emergency Care... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Hyperoxia and Hypocapnia During Pediatric Extracorporeal Membrane Oxygenation: Associations With Complications, Mortality, and Functional Status Among Survivors. | ## OBJECTIVES
To determine the frequency of hyperoxia and hypocapnia during pediatric extracorporeal membrane oxygenation and their relationships to complications, mortality, and functional status among survivors.
## DESIGN
Secondary analysis of data collected prospectively by the Collaborative Pediatric Critical Care ... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Hyperoxia, hypocapnia and hypercapnia as outcome factors after cardiac arrest in children. | ## PURPOSE
Arterial hyperoxia after resuscitation has been associated with increased mortality in adults. The aim of this study was to test the hypothesis that post-resuscitation hyperoxia and hypocapnia are associated with increased mortality after resuscitation in pediatric patients.
## METHODS
We performed a prospec... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Relationship between arterial partial oxygen pressure after resuscitation from cardiac arrest and mortality in children. | ## BACKGROUND
Observational studies in adults have shown a worse outcome associated with hyperoxia after resuscitation from cardiac arrest. Extrapolating from adult data, current pediatric resuscitation guidelines recommend avoiding hyperoxia. We investigated the relationship between arterial partial oxygen pressure an... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Hyperoxia and hypoxia in children resuscitated from cardiac arrest. | ## BACKGROUND
Ischemia depletes antioxidant reserves and impairs mitochondrial electron transport. Oxygen within blood reperfusing ischemic tissue can form free radicals, worsen oxidative stress, and exacerbate tissue injury (reperfusion injury). One strategy for limiting reperfusion injury is to limit delivery of "lux... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Hyperoxia in pediatric severe traumatic brain injury (TBI): a comparison of patient classification by cutoff versus cumulative (area-under-the-curve) analysis. | ## OBJECTIVE
Hyperoxia is associated with adverse outcome in severe traumatic brain injury (TBI). This study explored differences in patient classification of oxygen exposure by PaO
## METHODS
Retrospective, explorative study including children (<18 years) with accidental severe TBI (2002-2015). Oxygen exposure analysi... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Incidence of hyperoxia and related in-hospital mortality in critically ill patients: a retrospective data analysis. | ## BACKGROUND
Mechanical ventilation with oxygen is life-saving, however, may result in hyperoxia. The aim was to analyse the incidence and duration of hyperoxia burden and related in-hospital mortality in critically ill patients.
## METHODS
Patients of all ages admitted to intensive care units (ICUs) and with mechanic... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Post return of spontaneous circulation factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study. | ## INTRODUCTION
Most studies have analyzed pre-arrest and resuscitation factors associated with mortality after cardiac arrest (CA) in children, but many patients that reach return of spontaneous circulation die within the next days or weeks. The objective of our study was to analyze post-return of spontaneous circulat... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Admission Hyperoxia Is a Risk Factor for Mortality in Pediatric Intensive Care. | ## OBJECTIVES
To determine whether the association between hyperoxia and increased risk-adjusted mortality in adult intensive care patients is also observed in a pediatric intensive care population.
## DESIGN
Single-center retrospective analysis of admissions to ICU over a 5-year period commencing January 1, 2012, exam... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Maximum Pao2 in the First 72 Hours of Intensive Care Is Associated With Risk-Adjusted Mortality in Pediatric Patients Undergoing Mechanical Ventilation. | A relationship between Pao2 and mortality has previously been observed in single-center studies. We performed a retrospective cohort study of the Pediatric Health Information System plus database including patients less than or equal to 21 years old admitted to a medical or cardiac ICU who received invasive ventilation... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial. | ## BACKGROUND
Oxygen saturation monitoring for children receiving respiratory support is standard worldwide. No randomised clinical trials have compared peripheral oxygen saturation (SpO
## METHODS
We undertook an open, parallel-group randomised trial of children > 38 weeks completed gestation and < 16 years of age rec... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Admission PaO2 and Mortality in Critically Ill Children: A Cohort Study and Systematic Review. | ## OBJECTIVE
To describe the relationship between PaO2 at intensive care admission and mortality in critically ill children and to review systematically the literature describing this relationship.
## DESIGN
Cohort study: A review of consecutive tertiary pediatric intensive care admissions (January 2004 to December 201... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a Pediatric Intensive Care Unit. | ## IMPORTANCE
A high Pao2, termed hyperoxemia, is postulated to have deleterious health outcomes. To date, the association between hyperoxemia during the ongoing management of critical illness and mortality has been incompletely evaluated in children.
## OBJECTIVE
To examine whether severe hyperoxemia events are associ... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Early Hyperoxemia and Outcome Among Critically Ill Children. | ## OBJECTIVE
To identify whether a high PaO2 (hyperoxemia) at the time of presentation to the PICU is associated with in-hospital mortality.
## DESIGN
Single-center observational study.
## SETTING
Quaternary-care PICU.
## PATIENTS
Encounters admitted between January 1, 2009, and December 31, 2018.
## INTERVENTIONS
None... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | Hyperoxia Is Associated With Poor Outcomes in Pediatric Cardiac Patients Supported on Venoarterial Extracorporeal Membrane Oxygenation. | ## OBJECTIVES
Patients who require venoarterial extracorporeal membrane oxygenation because of cardiac failure frequently have supranormal blood oxygen tensions (hyperoxia). Recent studies have suggested worse outcomes in patients with hyperoxia after resuscitation from cardiac or respiratory arrests, presumably becaus... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >250 mm Hg (33 kPa) | High cumulative oxygen levels are associated with improved survival of children treated with mild therapeutic hypothermia after cardiac arrest. | ## AIM
The aim of this study was to analyze the relationship between the partial pressure of arterial oxygen (PaO2) and in-hospital (IH) mortality in children after cardiac arrest (CA) using the conventional cutoff analysis, which was compared with the cumulative analysis, a new method in PaO2 analysis. Additionally, w... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Early oxygenation and ventilation measurements after pediatric cardiac arrest: lack of association with outcome. | ## OBJECTIVES
To explore oxygenation and ventilation status early after cardiac arrest in infants and children. We hypothesize that hyperoxia is common and associated with worse outcome after pediatric cardiac arrest.
## DESIGN
Retrospective cohort study.
## SETTING
Fifteen hospitals within the Pediatric Emergency Care... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Hyperoxia and Hypocapnia During Pediatric Extracorporeal Membrane Oxygenation: Associations With Complications, Mortality, and Functional Status Among Survivors. | ## OBJECTIVES
To determine the frequency of hyperoxia and hypocapnia during pediatric extracorporeal membrane oxygenation and their relationships to complications, mortality, and functional status among survivors.
## DESIGN
Secondary analysis of data collected prospectively by the Collaborative Pediatric Critical Care ... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Hyperoxia, hypocapnia and hypercapnia as outcome factors after cardiac arrest in children. | ## PURPOSE
Arterial hyperoxia after resuscitation has been associated with increased mortality in adults. The aim of this study was to test the hypothesis that post-resuscitation hyperoxia and hypocapnia are associated with increased mortality after resuscitation in pediatric patients.
## METHODS
We performed a prospec... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Relationship between arterial partial oxygen pressure after resuscitation from cardiac arrest and mortality in children. | ## BACKGROUND
Observational studies in adults have shown a worse outcome associated with hyperoxia after resuscitation from cardiac arrest. Extrapolating from adult data, current pediatric resuscitation guidelines recommend avoiding hyperoxia. We investigated the relationship between arterial partial oxygen pressure an... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Hyperoxia and hypoxia in children resuscitated from cardiac arrest. | ## BACKGROUND
Ischemia depletes antioxidant reserves and impairs mitochondrial electron transport. Oxygen within blood reperfusing ischemic tissue can form free radicals, worsen oxidative stress, and exacerbate tissue injury (reperfusion injury). One strategy for limiting reperfusion injury is to limit delivery of "lux... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Hyperoxia in pediatric severe traumatic brain injury (TBI): a comparison of patient classification by cutoff versus cumulative (area-under-the-curve) analysis. | ## OBJECTIVE
Hyperoxia is associated with adverse outcome in severe traumatic brain injury (TBI). This study explored differences in patient classification of oxygen exposure by PaO
## METHODS
Retrospective, explorative study including children (<18 years) with accidental severe TBI (2002-2015). Oxygen exposure analysi... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Incidence of hyperoxia and related in-hospital mortality in critically ill patients: a retrospective data analysis. | ## BACKGROUND
Mechanical ventilation with oxygen is life-saving, however, may result in hyperoxia. The aim was to analyse the incidence and duration of hyperoxia burden and related in-hospital mortality in critically ill patients.
## METHODS
Patients of all ages admitted to intensive care units (ICUs) and with mechanic... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Post return of spontaneous circulation factors associated with mortality in pediatric in-hospital cardiac arrest: a prospective multicenter multinational observational study. | ## INTRODUCTION
Most studies have analyzed pre-arrest and resuscitation factors associated with mortality after cardiac arrest (CA) in children, but many patients that reach return of spontaneous circulation die within the next days or weeks. The objective of our study was to analyze post-return of spontaneous circulat... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Admission Hyperoxia Is a Risk Factor for Mortality in Pediatric Intensive Care. | ## OBJECTIVES
To determine whether the association between hyperoxia and increased risk-adjusted mortality in adult intensive care patients is also observed in a pediatric intensive care population.
## DESIGN
Single-center retrospective analysis of admissions to ICU over a 5-year period commencing January 1, 2012, exam... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Maximum Pao2 in the First 72 Hours of Intensive Care Is Associated With Risk-Adjusted Mortality in Pediatric Patients Undergoing Mechanical Ventilation. | A relationship between Pao2 and mortality has previously been observed in single-center studies. We performed a retrospective cohort study of the Pediatric Health Information System plus database including patients less than or equal to 21 years old admitted to a medical or cardiac ICU who received invasive ventilation... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial. | ## BACKGROUND
Oxygen saturation monitoring for children receiving respiratory support is standard worldwide. No randomised clinical trials have compared peripheral oxygen saturation (SpO
## METHODS
We undertook an open, parallel-group randomised trial of children > 38 weeks completed gestation and < 16 years of age rec... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Admission PaO2 and Mortality in Critically Ill Children: A Cohort Study and Systematic Review. | ## OBJECTIVE
To describe the relationship between PaO2 at intensive care admission and mortality in critically ill children and to review systematically the literature describing this relationship.
## DESIGN
Cohort study: A review of consecutive tertiary pediatric intensive care admissions (January 2004 to December 201... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a Pediatric Intensive Care Unit. | ## IMPORTANCE
A high Pao2, termed hyperoxemia, is postulated to have deleterious health outcomes. To date, the association between hyperoxemia during the ongoing management of critical illness and mortality has been incompletely evaluated in children.
## OBJECTIVE
To examine whether severe hyperoxemia events are associ... | True |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Early Hyperoxemia and Outcome Among Critically Ill Children. | ## OBJECTIVE
To identify whether a high PaO2 (hyperoxemia) at the time of presentation to the PICU is associated with in-hospital mortality.
## DESIGN
Single-center observational study.
## SETTING
Quaternary-care PICU.
## PATIENTS
Encounters admitted between January 1, 2009, and December 31, 2018.
## INTERVENTIONS
None... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | Hyperoxia Is Associated With Poor Outcomes in Pediatric Cardiac Patients Supported on Venoarterial Extracorporeal Membrane Oxygenation. | ## OBJECTIVES
Patients who require venoarterial extracorporeal membrane oxygenation because of cardiac failure frequently have supranormal blood oxygen tensions (hyperoxia). Recent studies have suggested worse outcomes in patients with hyperoxia after resuscitation from cardiac or respiratory arrests, presumably becaus... | False |
34985516 | Association of Arterial Hyperoxia With Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis. | What is the association between arterial hyperoxia and outcomes in critically ill children admitted to the pediatric intensive care unit? | The citations were screened independently by 2 of us (T.A.L. and N.S.G.) on title and abstract, and discrepancies were resolved through discussion. Full-text articles on potentially eligible studies were retrieved and checked independently for eligibility. Eligible studies were those including patients admitted to the ... | Random-Effects Meta-analysis (Subtotals Only) of Hyperoxia (Categorical Exposure) on Mortality, at Longest Follow-up, Stratified by Threshold of Hyperoxia (Pao2) - >300 mm Hg (40 kPa) | High cumulative oxygen levels are associated with improved survival of children treated with mild therapeutic hypothermia after cardiac arrest. | ## AIM
The aim of this study was to analyze the relationship between the partial pressure of arterial oxygen (PaO2) and in-hospital (IH) mortality in children after cardiac arrest (CA) using the conventional cutoff analysis, which was compared with the cumulative analysis, a new method in PaO2 analysis. Additionally, w... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | Text to Quit China: An mHealth Smoking Cessation Trial. | ## PURPOSE
To assess the feasibility, acceptability, and efficacy of a text message-based smoking cessation intervention in China.
## DESIGN
Study design was a randomized control trial with a 6-month follow-up assessment of smoking status.
## SETTING
Zhejiang, Heilongjiang, and Shaanxi provinces in China provided the s... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | A Feasible and Efficacious Mobile-Phone Based Lifestyle Intervention for Filipino Americans with Type 2 Diabetes: Randomized Controlled Trial. | ## BACKGROUND
Filipino Americans have a high prevalence of obesity, type 2 diabetes (T2D), and cardiovascular disease compared with other Asian American subgroups and non-Hispanic whites. Mobile health (mHealth) weight loss interventions can reduce chronic disease risks, but these are untested in Filipino Americans wit... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | Short-term effects of a smoking prevention website in American Indian youth. | ## BACKGROUND
The rate of smoking commercial tobacco products among American Indian youth is double the rate for white youth. Interventions are needed to reduce this disparity.
## OBJECTIVE
To test the feasibility of a Web-based intervention to influence attitudes toward and intentions about smoking cigarettes among Am... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | Evaluation of the Computer-Based Intervention Program Stayingfit Brazil to Promote Healthy Eating Habits: The Results from a School Cluster-Randomized Controlled Trial | Interventions via the Internet are promising regarding the promotion of healthy habits among youth. The objective of this study was to evaluate the effect of an adapted version of StayingFit to promote healthy eating habits and the measurement adequacy of anthropometric markers among adolescents. A web school-based 12-... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | An Experimental Feasibility Study of a Hybrid Telephone Counseling/Text Messaging Intervention for Post-Discharge Cessation Support Among Hospitalized Smokers in Brazil. | ## OBJECTIVE
Text messaging interventions are effective. Despite high utilization of smartphones, few studies evaluate text messaging for cessation in middle-/lower-income countries. Initiating tobacco treatment in hospitals is an effective but underutilized approach for reaching smokers. We evaluated a hybrid phone co... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | Web-Based Intervention for Physical Activity and Fruit and Vegetable Intake Among Chinese University Students: A Randomized Controlled Trial. | ## BACKGROUND
Ample evidence demonstrates that university students are at high risk for sedentary behaviors and inadequate fruit and vegetable intake (FVI). Internet-based interventions for multiple health behavior appear to be promising in changing such unhealthy habits. Limited randomized controlled trials have teste... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | Dulce Digital: An mHealth SMS-Based Intervention Improves Glycemic Control in Hispanics With Type 2 Diabetes. | ## OBJECTIVE
Type 2 diabetes is growing in epidemic proportions and disproportionately affects lower-income, diverse communities. Text messaging may provide one of the most rapid methods to overcome the "digital divide" to improve care.
## RESEARCH DESIGN AND METHODS
A randomized, nonblinded, parallel-groups clinical t... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | Linguistic and Cultural Adaptation of a Computer-Based Counseling Program (CARE+ Spanish) to Support HIV Treatment Adherence and Risk Reduction for People Living With HIV/AIDS: A Randomized Controlled Trial. | ## BACKGROUND
Human immunodeficiency virus (HIV) disease in the United States disproportionately affects minorities, including Latinos. Barriers including language are associated with lower antiretroviral therapy (ART) adherence seen among Latinos, yet ART and interventions for clinic visit adherence are rarely develop... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | Randomized Trial of a Physical Activity Intervention for Latino Men: Activo. | ## INTRODUCTION
Latino men experience disproportionately high rates of diseases related to low physical activity, yet they are poorly represented in physical activity intervention trials. Efforts to promote physical activity in Latina women show promising results, yet such interventions are yet to be extended to Latino... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | The Intervention Effect of SMS Delivery on Chinese Adolescent's Physical Activity. | To examine the effects of short messaging service (SMS) frequency and timing on the efficacy of an SMS-intervention for Hong Kong Chinese adolescents, sixty nine students aged between 12 and 16 (mean age 13.75 ± 0.90) were recruited from five schools in Hong Kong. Participants were randomly assigned into one of five gr... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | Pasos Hacia La Salud: a randomized controlled trial of an internet-delivered physical activity intervention for Latinas. | ## BACKGROUND
Internet access has grown markedly in Latinos during the past decade. However, there have been no Internet-based physical activity interventions designed for Latinos, despite large disparities in lifestyle-related conditions, such as obesity and diabetes, particularly in Latina women. The current study te... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | Preventing alcohol-exposed pregnancy among an American Indian/Alaska Native population: effect of a screening, brief intervention, and referral to treatment intervention. | ## BACKGROUND
Fetal alcohol spectrum disorders are the result of alcohol-exposed pregnancies (AEP) and believed to be the leading known cause of developmental disabilities in the United States. Our objective was to determine whether a culturally targeted Screening, Brief Intervention, and Referral to Treatment (SBIRT) ... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. active controls in the short-term. - Due to substantial heterogeneity among the culturally adapted IMI of health promotion vs. active controls in long-term meta-analytical pooling did not perform. | A Smartphone App to Assist Smoking Cessation Among Aboriginal Australians: Findings From a Pilot Randomized Controlled Trial. | ## BACKGROUND
Mobile health (mHealth) apps have the potential to increase smoking cessation, but little research has been conducted with Aboriginal communities in Australia.
## OBJECTIVE
We conducted a pilot study to assess the feasibility and acceptability and explore the effectiveness of a novel mHealth app to assist... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | Text to Quit China: An mHealth Smoking Cessation Trial. | ## PURPOSE
To assess the feasibility, acceptability, and efficacy of a text message-based smoking cessation intervention in China.
## DESIGN
Study design was a randomized control trial with a 6-month follow-up assessment of smoking status.
## SETTING
Zhejiang, Heilongjiang, and Shaanxi provinces in China provided the s... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | A Feasible and Efficacious Mobile-Phone Based Lifestyle Intervention for Filipino Americans with Type 2 Diabetes: Randomized Controlled Trial. | ## BACKGROUND
Filipino Americans have a high prevalence of obesity, type 2 diabetes (T2D), and cardiovascular disease compared with other Asian American subgroups and non-Hispanic whites. Mobile health (mHealth) weight loss interventions can reduce chronic disease risks, but these are untested in Filipino Americans wit... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | Short-term effects of a smoking prevention website in American Indian youth. | ## BACKGROUND
The rate of smoking commercial tobacco products among American Indian youth is double the rate for white youth. Interventions are needed to reduce this disparity.
## OBJECTIVE
To test the feasibility of a Web-based intervention to influence attitudes toward and intentions about smoking cigarettes among Am... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | Evaluation of the Computer-Based Intervention Program Stayingfit Brazil to Promote Healthy Eating Habits: The Results from a School Cluster-Randomized Controlled Trial | Interventions via the Internet are promising regarding the promotion of healthy habits among youth. The objective of this study was to evaluate the effect of an adapted version of StayingFit to promote healthy eating habits and the measurement adequacy of anthropometric markers among adolescents. A web school-based 12-... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | An Experimental Feasibility Study of a Hybrid Telephone Counseling/Text Messaging Intervention for Post-Discharge Cessation Support Among Hospitalized Smokers in Brazil. | ## OBJECTIVE
Text messaging interventions are effective. Despite high utilization of smartphones, few studies evaluate text messaging for cessation in middle-/lower-income countries. Initiating tobacco treatment in hospitals is an effective but underutilized approach for reaching smokers. We evaluated a hybrid phone co... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | Web-Based Intervention for Physical Activity and Fruit and Vegetable Intake Among Chinese University Students: A Randomized Controlled Trial. | ## BACKGROUND
Ample evidence demonstrates that university students are at high risk for sedentary behaviors and inadequate fruit and vegetable intake (FVI). Internet-based interventions for multiple health behavior appear to be promising in changing such unhealthy habits. Limited randomized controlled trials have teste... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | Dulce Digital: An mHealth SMS-Based Intervention Improves Glycemic Control in Hispanics With Type 2 Diabetes. | ## OBJECTIVE
Type 2 diabetes is growing in epidemic proportions and disproportionately affects lower-income, diverse communities. Text messaging may provide one of the most rapid methods to overcome the "digital divide" to improve care.
## RESEARCH DESIGN AND METHODS
A randomized, nonblinded, parallel-groups clinical t... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | Linguistic and Cultural Adaptation of a Computer-Based Counseling Program (CARE+ Spanish) to Support HIV Treatment Adherence and Risk Reduction for People Living With HIV/AIDS: A Randomized Controlled Trial. | ## BACKGROUND
Human immunodeficiency virus (HIV) disease in the United States disproportionately affects minorities, including Latinos. Barriers including language are associated with lower antiretroviral therapy (ART) adherence seen among Latinos, yet ART and interventions for clinic visit adherence are rarely develop... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | Randomized Trial of a Physical Activity Intervention for Latino Men: Activo. | ## INTRODUCTION
Latino men experience disproportionately high rates of diseases related to low physical activity, yet they are poorly represented in physical activity intervention trials. Efforts to promote physical activity in Latina women show promising results, yet such interventions are yet to be extended to Latino... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | The Intervention Effect of SMS Delivery on Chinese Adolescent's Physical Activity. | To examine the effects of short messaging service (SMS) frequency and timing on the efficacy of an SMS-intervention for Hong Kong Chinese adolescents, sixty nine students aged between 12 and 16 (mean age 13.75 ± 0.90) were recruited from five schools in Hong Kong. Participants were randomly assigned into one of five gr... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | Pasos Hacia La Salud: a randomized controlled trial of an internet-delivered physical activity intervention for Latinas. | ## BACKGROUND
Internet access has grown markedly in Latinos during the past decade. However, there have been no Internet-based physical activity interventions designed for Latinos, despite large disparities in lifestyle-related conditions, such as obesity and diabetes, particularly in Latina women. The current study te... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | Preventing alcohol-exposed pregnancy among an American Indian/Alaska Native population: effect of a screening, brief intervention, and referral to treatment intervention. | ## BACKGROUND
Fetal alcohol spectrum disorders are the result of alcohol-exposed pregnancies (AEP) and believed to be the leading known cause of developmental disabilities in the United States. Our objective was to determine whether a culturally targeted Screening, Brief Intervention, and Referral to Treatment (SBIRT) ... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI of health promotion vs. passive controls. - Due to few numbers of studies (two studies reported data in the long-term, two in the short-term, while one study reported dichotomous outcome) comparing culturally adapted IMI to a passive control group, meta-analytic pooling did not perform... | A Smartphone App to Assist Smoking Cessation Among Aboriginal Australians: Findings From a Pilot Randomized Controlled Trial. | ## BACKGROUND
Mobile health (mHealth) apps have the potential to increase smoking cessation, but little research has been conducted with Aboriginal communities in Australia.
## OBJECTIVE
We conducted a pilot study to assess the feasibility and acceptability and explore the effectiveness of a novel mHealth app to assist... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | Text to Quit China: An mHealth Smoking Cessation Trial. | ## PURPOSE
To assess the feasibility, acceptability, and efficacy of a text message-based smoking cessation intervention in China.
## DESIGN
Study design was a randomized control trial with a 6-month follow-up assessment of smoking status.
## SETTING
Zhejiang, Heilongjiang, and Shaanxi provinces in China provided the s... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | A Feasible and Efficacious Mobile-Phone Based Lifestyle Intervention for Filipino Americans with Type 2 Diabetes: Randomized Controlled Trial. | ## BACKGROUND
Filipino Americans have a high prevalence of obesity, type 2 diabetes (T2D), and cardiovascular disease compared with other Asian American subgroups and non-Hispanic whites. Mobile health (mHealth) weight loss interventions can reduce chronic disease risks, but these are untested in Filipino Americans wit... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | Short-term effects of a smoking prevention website in American Indian youth. | ## BACKGROUND
The rate of smoking commercial tobacco products among American Indian youth is double the rate for white youth. Interventions are needed to reduce this disparity.
## OBJECTIVE
To test the feasibility of a Web-based intervention to influence attitudes toward and intentions about smoking cigarettes among Am... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | Evaluation of the Computer-Based Intervention Program Stayingfit Brazil to Promote Healthy Eating Habits: The Results from a School Cluster-Randomized Controlled Trial | Interventions via the Internet are promising regarding the promotion of healthy habits among youth. The objective of this study was to evaluate the effect of an adapted version of StayingFit to promote healthy eating habits and the measurement adequacy of anthropometric markers among adolescents. A web school-based 12-... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | An Experimental Feasibility Study of a Hybrid Telephone Counseling/Text Messaging Intervention for Post-Discharge Cessation Support Among Hospitalized Smokers in Brazil. | ## OBJECTIVE
Text messaging interventions are effective. Despite high utilization of smartphones, few studies evaluate text messaging for cessation in middle-/lower-income countries. Initiating tobacco treatment in hospitals is an effective but underutilized approach for reaching smokers. We evaluated a hybrid phone co... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | Web-Based Intervention for Physical Activity and Fruit and Vegetable Intake Among Chinese University Students: A Randomized Controlled Trial. | ## BACKGROUND
Ample evidence demonstrates that university students are at high risk for sedentary behaviors and inadequate fruit and vegetable intake (FVI). Internet-based interventions for multiple health behavior appear to be promising in changing such unhealthy habits. Limited randomized controlled trials have teste... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | Dulce Digital: An mHealth SMS-Based Intervention Improves Glycemic Control in Hispanics With Type 2 Diabetes. | ## OBJECTIVE
Type 2 diabetes is growing in epidemic proportions and disproportionately affects lower-income, diverse communities. Text messaging may provide one of the most rapid methods to overcome the "digital divide" to improve care.
## RESEARCH DESIGN AND METHODS
A randomized, nonblinded, parallel-groups clinical t... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | Linguistic and Cultural Adaptation of a Computer-Based Counseling Program (CARE+ Spanish) to Support HIV Treatment Adherence and Risk Reduction for People Living With HIV/AIDS: A Randomized Controlled Trial. | ## BACKGROUND
Human immunodeficiency virus (HIV) disease in the United States disproportionately affects minorities, including Latinos. Barriers including language are associated with lower antiretroviral therapy (ART) adherence seen among Latinos, yet ART and interventions for clinic visit adherence are rarely develop... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | Randomized Trial of a Physical Activity Intervention for Latino Men: Activo. | ## INTRODUCTION
Latino men experience disproportionately high rates of diseases related to low physical activity, yet they are poorly represented in physical activity intervention trials. Efforts to promote physical activity in Latina women show promising results, yet such interventions are yet to be extended to Latino... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | The Intervention Effect of SMS Delivery on Chinese Adolescent's Physical Activity. | To examine the effects of short messaging service (SMS) frequency and timing on the efficacy of an SMS-intervention for Hong Kong Chinese adolescents, sixty nine students aged between 12 and 16 (mean age 13.75 ± 0.90) were recruited from five schools in Hong Kong. Participants were randomly assigned into one of five gr... | True |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | Pasos Hacia La Salud: a randomized controlled trial of an internet-delivered physical activity intervention for Latinas. | ## BACKGROUND
Internet access has grown markedly in Latinos during the past decade. However, there have been no Internet-based physical activity interventions designed for Latinos, despite large disparities in lifestyle-related conditions, such as obesity and diabetes, particularly in Latina women. The current study te... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | Preventing alcohol-exposed pregnancy among an American Indian/Alaska Native population: effect of a screening, brief intervention, and referral to treatment intervention. | ## BACKGROUND
Fetal alcohol spectrum disorders are the result of alcohol-exposed pregnancies (AEP) and believed to be the leading known cause of developmental disabilities in the United States. Our objective was to determine whether a culturally targeted Screening, Brief Intervention, and Referral to Treatment (SBIRT) ... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active control conditions. - Forest plot presenting fixed effects meta-analysis of culturally adapted IMI for physical activity vs. active controls. | A Smartphone App to Assist Smoking Cessation Among Aboriginal Australians: Findings From a Pilot Randomized Controlled Trial. | ## BACKGROUND
Mobile health (mHealth) apps have the potential to increase smoking cessation, but little research has been conducted with Aboriginal communities in Australia.
## OBJECTIVE
We conducted a pilot study to assess the feasibility and acceptability and explore the effectiveness of a novel mHealth app to assist... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI for smoking cessation vs. active controls in short-term. - Three studies reported smoking cessation outcomes measuring short-term abstinence at the end of the intervention vs. active controls are presented on the forest plot. | Text to Quit China: An mHealth Smoking Cessation Trial. | ## PURPOSE
To assess the feasibility, acceptability, and efficacy of a text message-based smoking cessation intervention in China.
## DESIGN
Study design was a randomized control trial with a 6-month follow-up assessment of smoking status.
## SETTING
Zhejiang, Heilongjiang, and Shaanxi provinces in China provided the s... | False |
35322172 | Culturally adapting internet- and mobile-based health promotion interventions might not be worth the effort: a systematic review and meta-analysis. | Are culturally adapted internet- and mobile-based interventions (IMI) more effective than non-culturally adapted interventions in promoting health behaviors among culturally diverse populations? | The initial search was conducted in the following databases on 26. August 2019: Cochrane Central Register of Controlled Trials (CENTRAL), EbscoHost/MEDLINE, Ovid/Embase, EbscoHost/PsychINFO, and Web of Science. A combination of keywords (including MeSH terms) indicating culturally adapted IMI for health promotion has b... | Summary of culturally adapted IMI for smoking cessation vs. active controls in short-term. - Three studies reported smoking cessation outcomes measuring short-term abstinence at the end of the intervention vs. active controls are presented on the forest plot. | A Feasible and Efficacious Mobile-Phone Based Lifestyle Intervention for Filipino Americans with Type 2 Diabetes: Randomized Controlled Trial. | ## BACKGROUND
Filipino Americans have a high prevalence of obesity, type 2 diabetes (T2D), and cardiovascular disease compared with other Asian American subgroups and non-Hispanic whites. Mobile health (mHealth) weight loss interventions can reduce chronic disease risks, but these are untested in Filipino Americans wit... | True |
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