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UniProt_function_text_descriptions

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Q48V07
NRDI_STRPM
Protein NrdI
MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYLLIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQKLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQINNLITERTHPCHKPMRHTSH
Probably involved in ribonucleotide reductase function. {ECO:0000255|HAMAP-Rule:MF_00128}.
Q48V20
YABA_STRPM
Initiation-control protein YabA
MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLENTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRELLDRK
Involved in initiation control of chromosome replication. {ECO:0000255|HAMAP-Rule:MF_01159}.
Q48V42
YIDD_STRPM
Putative membrane protein insertion efficiency factor
MMKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGTKGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q493F6
FETP_BLOPB
Probable Fe(2+)-trafficking protein
MSKIIYCVFLKKYAEGLDAPCYPGALGKYIYEHISNIAWMQWQDKQTILINENKLNMMNIADRTILEKEMKIFLFGKNFSIKNN
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.
Q49UZ5
YABA_STAS1
Initiation-control protein YabA
MNRSDIFEKLANLEANINQINSDMGNLKKLTVEVIEENVALQIENENLKTLIDKEEKSKAVENGKKLPKKQPLRSKDNLAMLYKEGFHICNGELFGKHRKGDDCLFCLEVLSE
Involved in initiation control of chromosome replication. {ECO:0000255|HAMAP-Rule:MF_01159}.
Q49V07
SP5G_STAS1
Putative septation protein SpoVG
MKVTDVRLRKIQTDGRMKALVSITLDESFVVHDLRVIEGNTGLFVAMPSKRTPDGEFRDIAHPINSEMRQEIQDAVMKVYEETDEVIPDRNAQSSDDSEEA
Could be involved in septation. {ECO:0000255|HAMAP-Rule:MF_00819}.
Q49V31
CTSR_STAS1
Transcriptional regulator CtsR
MHNMSDIIEQYIKKLFEDTNEDVVEIRRTNIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDETGYINHLLQLVGPSISQQQAYYIVDGLLDKSYINEREAKMIYAVIDRETLKMDILSRDIIRANIIKRLLHVINYY
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Q49X20
Y1533_STAS1
UPF0122 protein SSP1533
MSQNDLIKTIRMNYLFDFYQALLTKKQRNYLELFYLQDYSLSEIANTFDVSRQAVYDNIRRTGDLVEDYEEKLGLYRNFEQRQNLYEQIKQHINDPEQIKKYIQALEDLD
Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255|HAMAP-Rule:MF_00245}.
Q49YM0
YIDD_STAS1
Putative membrane protein insertion efficiency factor
MKTIFLGLIHIYQRFISPLTPATCRFYPTCSEYTREAIVVYGPFKGTWLGIKRISKCHPLHKGGFDPVPLKKTKHKKDKNINK
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q49ZC7
ASP23_STAS1
Alkaline shock protein 23
MAVDNNKAKQAYDNQTGVNEKEQEQRQEQQNQQPEFTNKLSFSDEVIEKIAGIAAREVSGILEMKGGFVDNISSSFGSNNNVSQGVSVEVGEKQAAVDLKVVLEYGESAPKIFRKVTDLVKEQVKYITGLDVVEVNMRVEDVMTKKEWSQKNEKSQSSNNEDKGLQ
May play a key role in alkaline pH tolerance.
Q4A656
HRCA_MYCS5
Heat-inducible transcription repressor HrcA
MKQLKKQHEEILKAVVGAYLTQKNEISSALLVKNYGIKFSPAKVRYLMTALEDEGLLVKETKSSGRKPTNKGLEYYAKFLSNAFDLKLINNLEKIFLNRKDNIYNTIEEVTKELASLTGATFVTKFKDPNLILKSINLFEVSESLATIILVVSNGEVLSRKIDIPENKAIKISDLKIAMNIFQDNLIDCKLIDLEKRILLLKDILAEKIIQYEDVIESYVKSILGIGIKSQIYGRENIILSRKIAREDVNEILNILEKNSIWDALEKNSNDFEEIRISINSKGAFFSKRIDENNNLTEISVVAPNESDSNSIKSGIMLLTKIITNNINEKEKDKNERKHS
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
Q4A902
HRCA_MESH7
Heat-inducible transcription repressor HrcA
MPKLDSKKEKYLKQIVENFIKTGESIGSLNLKQSYGIKKSPSYLRAIMNQLEKEGFLEKSHSSSGRIPTLQGFQYYAEFLSFDENENLANKLKDLFARRRINIENTISEAVKLISESVGTTLIATTNNENERLMSINLTQISQNEGIIVVVSSSGNVENKKITFSEQIPRQDVKIAIRLFQERLINTPLLEISSKLAILKQELEKQIKHSDELLHHFMEKIFNFQVQNKSNIYNKNSLILDKEISRAKLVDLLYIIEKKSIWEMLEDRTTKDDDTLKISIKSPEVSFISKKFEKFLPIKEISMVGAAKKINYSAARTGIKLLEDFLSNKSKIRKG
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.
Q4D248
EFTS1_TRYCC
Elongation factor Ts 1, mitochondrial (EF-Ts 1) (EF-TsMt 1)
MLCLTRLRANVNKVAFMEMVKDLRFRTEAPIAECGAALKETHGDVEKAMEVLRKKGAARAMKKRSRVTEHGSVVACVGGLFGAAVITVCSETDFAARSAQFQNTCARVKVALQRKIIDSKGDVLTNPTEAHRSLVEATAEDIRSSIAVLGENVTIKSVESLRLAPHVAEHISIGSYTHGSLDVPDVGRIAGVVAVSRLDPTKEVQASTLTDVARHFVASSGAEGNYAHQNFFGTEETVGQWLKRHGLCFSSSLVVDFGKEPITHTASQPRNAVKHPEG
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. {ECO:0000255|HAMAP-Rule:MF_03135}.
Q4FNF0
YIDD_PELUB
Putative membrane protein insertion efficiency factor
MNIISNILIGLIKFYKMVISPYLTPSCRYLPTCSEYTIECLRTYGLVKAISKSTKRIFSCHPIKILGGGEGFDPVNKEFKAKK
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q4FPR6
YIDD_PSYA2
Putative membrane protein insertion efficiency factor
MYFFIKTINKYLYKLIYSFIVFYQKIISPILPARCRYYPTCSNYGKQALAWYGVWNGSLLLLKRIGRCHPLGGHGIDFVPLPLASYHYQHVSLIMSACMKAQGLYVYRDNNGYVARLNHMMKLT
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q4FQX4
SDHE_PSYA2
FAD assembly factor SdhE
MTINNQPEPTNEQRRIIYQARRGLKELDFYFEPYIKELYLTAEAAEQESFAQMLTHEDPDLLDYFTNQSRPEDDAMWALVNKIKTWRHSKSLS
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q4FVJ7
FETP_PSYA2
Probable Fe(2+)-trafficking protein
MTATFNPQANTVFCRKYQQDLPKMPHPPFPNKKGQELQETVSEKAWKEWLEQQTMLINENHLSMLDPKAKQFLTEQRDKFLDNEDYERAQGWTPES
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.
Q4IBL8
DML1_GIBZE
Protein DML1
MREIVTLQLDQESYFTYSSDEKSLIDHNVHWRAGLGADGSETFLPRTVIYDLKGGFGSLRKINALYEAESESAPEALWSGQSVVHKQTPITPSEYQQSLDAGSEPAQLTTSNVRYWSDFSRVYFHPKSLNQLYDFELNSTTMPFERFSMGTELFSMLDREHDLADRDFRPFAEECDRMQGIQVFTTIDDAWGGFTSSYLESLRDDFPKTTIWTWGLQSPLLDISRAKRQLRLVNTAHSIEQLCTQSTTVVPLALPEEDMTTSVSMDRRSPWHTSALMAAAIETATLPSRLTQGSSEQAGSLDVLAESLNVNGNQPLASMRMSLAPAKDSPEDSRINVDFFQVGRVWSRQHVARLDTHKHVFGEILSYRDLDPLGHDNENGHLAPGERPIIGNSIVRKYDSALRFPLLDAYPQIYPQLAGNSDASLQTTLSTNSSIVQRIRTLRTESARLVPVNEREDLGNGLADLADAYQEGWFSGSDEDDDDL
Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.
Q4JBF2
Y468_SULAC
Putative antitoxin Saci_0468
MPKVITISDDVYDKLSKLKKGRSFSETINELIEFYNKNRKGNKDVLLQMFGILNEEEATEMASETLNIRKSFRFRAVENGDT
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. {ECO:0000255|HAMAP-Rule:MF_00794}.
Q4JSC3
YIDD_CORJK
Putative membrane protein insertion efficiency factor
MARRLILGYQSYLSPLKMGPTCRFEPTCSNYALIAISRHGLIKGSVLALGRLARCGPWHPGGWDPVPPRRPLCSWGGRRR
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q4KGR0
SDHE_PSEF5
FAD assembly factor SdhE
MVEDVELNRLYWHSRRGMLELDVLLVPFVREVYPHLNETDRECYRKLLECEDQDMFGWFMERSESEDPELQRMVRMILDRVQPK
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q4KJT2
FETP_PSEF5
Probable Fe(2+)-trafficking protein
MTRTVMCRKYQEELPGLERPPYPGAKGQDIFDHVSAKAWADWQKHQTLLINEKRLNMMNADDRKYLQGEMDKFFSGEEYAKADGYVPPAE
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.
Q4KRW2
M22_HRSV
Protein M2-2
MTMPKIMILPDKYPCSITSILITSRCRVTMYNRKNTLYFNQNNPNNHMYSPNQTFNEIHWTSQDLIDTIQNFLQHLGVIEDIYTIYILVS
Mediates the regulatory switch from transcription to RNA replication. Acts late in infection by inhibiting viral transcription and up-regulating RNA replication. Inhibition of transcription by protein M2-2 requires phosphorylation of the phosphoprotein.
Q4L3F5
SP5G_STAHJ
Putative septation protein SpoVG
MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLFVAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVIPDKNASSEDSDEA
Could be involved in septation. {ECO:0000255|HAMAP-Rule:MF_00819}.
Q4L3I1
CTSR_STAHJ
Transcriptional regulator CtsR
MHNMSDIIEQYIKKLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQIIGPSISQQQAYYILDGLLDKGLISEREARMIQVIVDRETLKMDVVARDIIRANILKRLLPIINFY
Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Q4L5T8
Y1678_STAHJ
UPF0122 protein SH1678
MGKNDLVKTLRMNYLFDFYQTLLTEKQRNYMELFYLRDYSLSEIAETFDVSRQAVYDNIRRTGDLVEDYEAKLNLYEKFEQRRKIYDDMKQTLNDSKKLEQYINQLEELE
Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255|HAMAP-Rule:MF_00245}.
Q4L7D2
YIDD_STAHJ
Putative membrane protein insertion efficiency factor
MLKKLFLGIIHIYQRYISPMTPPTCRFYPTCSEYTREAIEVYGPFKGGYMGIRRILKCHPLHKGGFDPVPLKKDKHRH
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q4QLR1
YIDD_HAEI8
Putative membrane protein insertion efficiency factor
MAETHSLGTKILIKIIRLYQIMISPFIGARCRFVPTCSCYGIEALKTHGLLKGGWLTLKRVLKCHPLNAGGFDPVPPKTNNNDEKK
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q4QMD9
FETP_HAEI8
Probable Fe(2+)-trafficking protein
MARTVFCEYLKKEAEGLDFQLYPGELGKRIFDSVSKQAWGEWIKKQTMLVNEKKLNMMNAEHRKLLEQEMVNFLFEGKDVHIEGYVPPSN
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.
Q4QMW1
SDHE_HAEI8
FAD assembly factor SdhE
MEKYNKLRIEWDCRRGMLELDKIIMPFYLKHFDELTDDKKDIFIRLLASTDLQLFSWFFNRGKSSDSEIQSMVEYIQNVQKITTN
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q4QPN5
FDHE_HAEI8
Protein FdhE homolog
MSIKILSESEIKQVANSYQAPAVLFANPKNLYQRRAKRLRDLAQNHPLSDYLLFAADIVESQLSTLEKNPLPPQQLEQLNAIEPLNAKTFKRDSIWREYLTEILDEIKPKANEQIAATIEFLEKASSAELEEMANKLLAQEFNLVSSDKAVFIWAALSLYWLQAAQQIPHNSQVENAENLHHCPVCGSLPVASIVQIGTSQGLRYLHCNLCESEWNLVRAQCTNCNSHDKLEMWSLNEELALVRAETCGSCESYLKMMFQEKDPYVEPVADDLASIFLDIEMEEKGFARSGLNPFIFPAEDA
Necessary for formate dehydrogenase activity. {ECO:0000255|HAMAP-Rule:MF_00611}.
Q4R6F2
EMARD_MACFA
Endoplasmic reticulum membrane-associated RNA degradation protein (ER membrane-associated RNA degradation protein)
VLIGDPITTCLSPSVYDIICNLGFQLRENCDINSIVTQNGEVCWKTITDCVSYTESDQGLDYWGSVRLLGPVCEAVHSHFLSLTKGQFEIRYAPWFQWTSFPELFPEIFDALESLQSPAISLSLMKLTSCLERALGDVFLLIGKECPFLLRDLLASEELAQVFGQSVMNVLKVFVGSPCGLNLRNVLWHGFASPEEVPPKYCSMMMLLTAGLGQLLKSYLQKTKLTLAHRSFITPTNLEDLIVFPDVTYEVLSVLEEAMTKSAFILKIMLPYWEVALVKFKSHRFADCAILLLTQLETGLRNVFATLNRCPQRLLTAEILAKHLNDGKINQLPLFLGEPAMEFLWDFLNHQEGPRIRDHLSHGEINLHEFSKETTNQLLAFSVVLLLRFVDEGLLSVFKEKASVELLISLAEGYSSRCHPVFQLKKQVLSCEESIRVWALLPFPKELTWEAVRLEDNSETNACHSLITKMTDELYHHMPEDHCVLKDLDHLPTETWPQLLHELCSTPVRTLFCPRIVLEVLVVLRSIGKQCHRVSGQVTIASELRHRQWVERTLRSRQRQNYLRMWSSIRLLSPVLSLILFLITLELVNVHAVCGKNAHEYQQYLKFVKSILQYTENLVAYTSYEKNKWNETINLTHTVLLKIWTFSEKKQMLIHLAKKSTSKVLMKT
May play a role in neuronal migration during embryonic development.
Q4UM10
YIDD_RICFE
Putative membrane protein insertion efficiency factor
MTRILLLLLRFYQYFISPLLGNNCRFHPTCSEYAKEAITTHGTLKGLWLTFKRIIKCQPFCNGGYDAVPLSIKNSKLFNKKI
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q4UMA9
VAPB1_RICFE
Antitoxin VapB1
MQLFLRINMAQIIRATEFVRSFSDIMNRVYYKGESFDVQKGNHIVARITPAETKPSIAVRDLEEAFKNGPHLDPEDADQFMKDIEEIRRSTRQDIKKLVERWD
Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli neutralizes the effect of cognate toxin VapC1, partially inhibits the RNase activity of VapC1 in vitro.
Q4UN91
PARB_RICFE
Probable chromosome-partitioning protein ParB
MAKNKGLGRGLSSLLGEEVISIESEIIQIINIDKIRPNENQPRKNFEYDKIKELADSILNNGLLQPIIVDNNFQIIAGERRWRACKLAKVLEIPVIIKNLDARESMEIALIENIQRTDLTVMEEARGFKYLVENFNYTTEKLAERLGKSRSHIANLLRLNNLPQSIQDKVNENILSMGQARCLINHEHAEVMADHIISNDLNVRQTEELVRQWYKNEYTKSPNNNNKVGKRFLKDNATDNDLESLVKVLSEKFGIKVTIENYSLGGKLIFHYKNLEELDLILLKLN
Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity).
Q4UNC7
Y080_RICFE
Probable ABC transporter permease protein RF_0080
MLLNIANSVGKRTIKFAQSVGSFSLFSFAAVSSIIRPPLYLSLIIRQLLFIGFHSLPVVAMTTFFSGAVLALQSYTGFSRFSAESSIATVVVLSLTRELGPVLAGLMVAGRVGASIAAEIATMRVTEQVDALYTLSTDPIKYLVFPRVIAAIITMPCLVLIGDIIGVMGGYLVGVYKLDFNSTAYLTSTFHYLEPIDVISGLVKAGVFGFIISIISCYSGYYSGKGAKGVGRATTSAVVNSSILILISNYLITELFFKV
Could be part of an ABC transporter complex.
Q4UV74
SDHE_XANC8
FAD assembly factor SdhE
MEKEMDEDTLLKKLRWRCRRGMRELDQLFGRYLDRRWAQAPAAERAVFLQLLDCEDDKLWRWFMGYEACPDADNAALIADIRAMPA
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q4UVK1
YIDD_XANC8
Putative membrane protein insertion efficiency factor
MAYHWQVIGRLLIALLRFYKRFISPLLGPRCRFAPSCSEYAMTAIARFGPLRGSWLAARRLGRCHPFHPGGFDPVPDAPTSSPSSCRCKGPHP
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q4UW14
FETP_XANC8
Probable Fe(2+)-trafficking protein
MSRTVFCQYQQCDTEGLDFAPYPGELGQRIFAQIGKAGWQAWLAHQTMLINENRLSPRDPKHRAFLEAELQKFLFERNADKPEGYVDPLGEE
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.
Q4WES5
LCL2_ASPFU
Long chronological lifespan protein 2
MLSSWVRCLGALLFLASVAQAQFQFFEHMFGGGHQEHHQQNTQNSASDSARYQQLWEGTNCNKYLCPGTLACVDFPHHCPCAHPNVEDKVELGEGSAVCISKGGYKPGEAARKIELARKGLL
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
Q4XUG7
EFTS_PLACH
Elongation factor Ts, mitochondrial (EF-Ts) (EF-TsMt)
MRYSLFLEFFFVFVLTCSLDVICYKRTSSLNLVTDIKQIKNKSIHKRNRLYSSNENLKRLKYIREVTNASIQVCNDALKECNNDVDKAIELVRKNTKNGSFISTSVKTQKEGLICSDIMDDKIVLIELLTDSDFVARNNKFVTFLKNISKLCLHNEIIPPNIDVNDSVENFDTSLVAIDKIMQSPYTNSNGEINGTVSEELNYLRNIFREDIKIGRFSKYIKKNENEFLHYYIHNIVDGNNVGLSGVMLVIEIDNLNEKLKTKEKDIISFANDLCMHIISAKPVSVSIDKVNQNVVKKEMDIIRDSLKDLNKPENIITNMINGKMKKFYSNVVLLEQEYMLDDTKRKVSQVIKDFSKNNDLTINVKHFDNFIVGEKNILV
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. {ECO:0000255|HAMAP-Rule:MF_03135}.
Q4ZL10
YIDD_PSEU2
Putative membrane protein insertion efficiency factor
MRKLALVPIQFYRYAISPLMASHCRFYPSCSCYAYEAIENHGLLRGGWLSIRRLGRCHPWNPGGYDPVPAVPTSRSSSMAE
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q4ZLP3
FETP_PSEU2
Probable Fe(2+)-trafficking protein
MTRTVMCRKYKEELPGLERAPYPGAKGEDIFNHVSQKAWADWQKHQTLLINERRLNMMNAEDRKFLQTEMDKFLSGEEYAQAEGYVPPEK
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.
Q4ZPD1
SDHE_PSEU2
FAD assembly factor SdhE
MVEDVELNRLYWHSRRGMLELDVLLVPFVREVYPHLNDVDRDLYRRLLTCEDQDMFGWFMQRAESEDAELQRMVRMILDRVQPQ
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q502K3
ANR52_DANRE
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C)
MGVLNISDQPPLVQAIFNRNADEVKLFLHKKDEVNALDQERRTPLHAAAWLGDVHIMDLLISAGANVNAKDHVWLTPLHRAAASRNERAVGLLLRKGADVTARDKYWQTPLHIAAANRATRCVETLLPHVSSLNMADRTGRAPLHHAAQSGYQEMVKLLLNKGANLSASDKKDRQPIHWAAYLGHLEVVKLLVSQGSDKSCKDKRGYTPLHAAAASGHVDVVKYLLRNGAEIDEPNAFGNTALHVACYTGQEAVANELVNRGANVNQPNHRGYTPLHLAAVSTNGALCLELLVNNGADVNMQSKEGKSPLHMAAIHGRFTRSQILIQNGGEIDCVDRYGNTPLHVAAKYGHELLISTLMTNGADTARQGIHGMFPLHLAVLYGSSDCCRKLLSSGQLYSIVLSMSKEHVLSAGFDINTPDNFGRTCLHAAASGGNIECLNLLLSSGADMNKKDKFGRTPLHYAAANGRYQCVVVLVGAGAEVNERDRSGCTPLHYSAASTAFCRTDRPHASTHQNQEDGEKESFLCVEHLLDNGADPCLCNTKGYSAVHYAAAHGNKQNLELLLEMCFNTLGDKESNGSISPLHLAVESGHWECVTVLIESGVCVDVCDPVGRSVLYLASQRGHSRCVELLLSQSASCLLAEHRSKWGPLHVAAANGHSECLRMLLCSEGGADLVNVTDAEGQTPLMLAVLGGHTDCVHLLLERGACPDMKDRRGRTALHRGAVMGREDCLTALLSHNVSVLSRDFQGRSALHLAASCGHADILSNLLSAADHSQPQDPLTDRHGYTPAHWAAYHGHEDCLEVLLELKPCSIQEGNPFTPLHCALINGHSGSAELLLESSVCNSLVNIRDAKGRTPLHAAAVAEDVAGLQLVLRQGADIDAVDHSGRSALMVAADYGQSGAVALLLHRAKADLSLLDVNKNTALHLACSKAHEMCAMLILKEIHNPILINATNSMLQMPLHIAARNGLATVVQALLNRGATVLAVDEEGHTPALACASNKAVADCLALILSTMKPSSSTASSSSPSSPSLNLLKHCGITAACPPLPNGGLRHGYGKDRHGATIGLDGCLTE
Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates.
Q52071
NIFW_ENTAG
Nitrogenase-stabilizing/protective protein NifW
MDWFTRIEGVDELESAQSFFDFFELEVDPVLLRSRHLHIMAQFNQRLTAAVPVHFVDEEESDRADWRLARRLLAESYQHTVAGPLNTQSGLAVYQRNNGSFIGWNDLLEVRP
May protect the nitrogenase Fe-Mo protein from oxidative damage.
Q52312
INCC1_ECOLX
Protein IncC
MGAIHEETANRSPIPDGHQGAGDRAADHRHSARRAGRWPAPGGVCHFAGADQGGGVAGGQSRMGSSRGTAPRGLRASDGGTAGASSVHRQEVGSRRQEETGTQVMKTLVTAIQKGGQGKTFATCHLAFDFLERGLRVAVIDLDTQGNASFTLSAYQSGYLASQLFTGDTDDLRYWFGKREGESLALIAADANLANLDKMELSQAAAALRASVAALGEFFDVCLIDTAPSLGVAMTAAVLTADYMLSPIEMEAYSLQGMKKMVAVISNLRKQNPKLRFLGMVPNKVDARKPRHVNNLATLQQAYPQLILPFSIGARDSIAEALGEQMPVWKIKKTAARKATQEVRALADYVFTKMEIAQ
This is one of the proteins encoded by the trfB operon it is involved in plasmid maintenance and replication.
Q52892
NOEA_RHIME
Nodulation protein NoeA
MARMADSKLVAAAPRPGRVAGSFRDPSGQVFHFQDRILRTMDSAAAIEFASAERVMRQLVDEGRLVDFSDAEPSLHQLFQGSIARVLQHPLLEQITYPYEWSFAGLKAAALFHLQLQLDLLDQGFCLSDATAYNVQFEGSRPTFIDHLSIKPYRDGQLWYGHKQFCEQFLVPLLLRSVFDITHHSWYRGNLEGVPSADFVKLLSTRHWFSHKLFMHIILPAKLQSSRTSQTKVDLGDSRARRLPKDAFRAMLAQLYSWISGLKVDVGKQSVWQGYAANNTYTATQRSDKGQYVAEFVAQHKPRTIIDLGCNTGDFSYVALENGAEKAIGFDFDPHALDAAFDRSVQTSKNFLPLYLDARNPSPSQGWGERERQGFSSRFSADAVLALAFEHHLAIAHNVPLAEVVAWVTQVAPKGIIEFVPKEDETVRRMLAGREDIFSDYNEEAFASALSQKARVVNKHLIPGSKRTLYTFERSE
Not known does not seem to participate in nod factor synthesis but required for nodulation on some specific Medicago species such as M.littoralis.
Q52975
NOLS_SINM2
Nodulation protein NolS
MRSKPPSWGHEGIISRHPTKLLPIGLPGTGDLFAGSIVAGLARGVPLPRAVAIAQNLTSRAQDHANALGAGEVVLSEPESRRALVALDPN
Involved in nodulation of a particular host, M.lupulina.
Q52993
NFE1_RHIML
Protein nfe1
MAALRQVAFYGKGGIGNSKRKPELVTASIEDRSAGSPSKNKMHFQSRMNVAASMRGGDGLPPSVRCRLHLEDGTTRGERKERTRLAATFQSVSEERPRLHMPRRVTTTHTTLFVTFVGFTTPIVPSTVWSISRSNHLKQSN
Responsible for the nodulation efficiency and competitive ability of strain GR4 on alfalfa roots.
Q52DM9
DCN1_MAGO7
Defective in cullin neddylation protein 1
MPLTAVQKTLSAQFVHMTATNDKVAQKFLKNANWKLDIAADAYFNSNPNMATSSSSKPKLDKMFSDLQDTQEDSPDELGAGSAIEYASSLGVDPESVGIFVLMELVKAPAFGVITRSGFVEGWQATNAPASKSGQKDYIQSVIRNLPQDHELFKRVYRHAFIAGRETPEQRALPLENALVYWQCFFGPEMPHSKPWVAKSSQSGGTTDFLDLWTEYLKNNWSRTVSKDMWNQTLDFAVKSTADSTLSFWTPEGSWPSVIDGFVEWLRNKGIGVASGMEVDS
May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).
Q53121
PUFK_CERS4
Transcriptional regulatory protein PufK
MVPYRNPRHQHVASVLRSGG
Involved in the transcriptional regulation of pufB.
Q53750
COP2_STAAU
Protein cop
MTFNKIFKYLISLLFLSILFHTIIHKNNLVFSKTMHKKVAFFSFSFFFVWIRHLKRYNSMLEKATFFVLQTSYTNELKGLYIAGNSYPYYQDKKKLVFNSFQKPFKNHQSTKIPRE
Putative control of replication message.
Q54087
LRPR_STREQ
Leucine-rich protein
MELKDYFPEMQVGPHPLGDKEWVSVKEGDQYVHFPKSCLSEKERLLLEVGLGQYEVLQPLGSPWQRYLLDHQGNPPQLFETSQFIYLNHQQVLPADLVELLQQMIAGLEVILPISTTQTAFLCRQATSIKVLRSLEGLLPTLESDFGLALTMFVGNAWYQVAAGTLRECFEEECQLLTAYLKQKSGGKLLTFAEVMLWSILSHQSFPALTRQFHQFLNPQSDMADVVHALWSEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLHLKQLDDLAFAYLFLLKY
Not essential for viability or growth. Nevertheless, uncontrolled production in E.coli is detrimental to the normal physiology of the bacteria.
Q54709
OPCA_SYNE7
Putative OxPP cycle protein OpcA
MTTATPLLSLQKPTPIALAEIEESLSQLWANQQHSGAGALVSRAATFSIVVYEPEEFQQILAALGLYHGHLDGLHGPMTRAAIAQAQTQFGLPSTGRPDSATFKALRQAYQALKHSPSLTNQDLRGAVLSNVIATQNPCRIVSLCPTLEGDRPISAEVSAYCPITSAKQASLICCEAVTLRGSQAEMEAIGTFVSELLLPGLPRYVWWKATPNPEQLLFQQLANSCNCMIFDSSYFSDPEAEFLRFQDLIDQETYIADLNWHRLAAWQELTAAAFDPPERRDGLLEVDQLVIDYEKGNPAQALMYMGWIASRLGWQPVSYRCEGGEYDLRQIEFRTEDDRMVKVELAGIPVGDPGLVLGDLIALRLTSENPDADCCTILCSETTGCMRMEAGGGAQSCRTEQVAPPSNETSESLLAMQMQRWGRDALYEESLAVIAVALRQRTHA
May be involved in the functional assembly of glucose 6-phosphate dehydrogenase.
Q54HW1
PSD10_DICDI
26S proteasome non-ATPase regulatory subunit 10 (26S proteasome regulatory subunit p28)
MSGTKFRTGGTKEDDLLEFVKVGKLLEVKDLIENQGVKADCKDEDERTPLHWAAAKGQISVAQYLMDNCKCSPNTNDDGGWTPLTSATSAGHTHMVKLLLEFGADPNTVNDSKRTPLHYASSKGRSDIVDLLLTHGAKNRKDDTGSAPIHRASSNGSVATVERLLKGEANINSTNNEGDTPLHIAAEYNHEDVVECLLKHGADTTIENKDSKTPIDMSSSQTIKYLIKEFKK
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC).
Q54K76
CUTC_DICDI
Copper homeostasis protein cutC homolog
MSEQDIKFEVCVDSLSSCIEAINGGASRLELCSSLFSGGLTPSYGLMKTLKEYIENHEISIDIFVMIRPRSGDFLYNQDEITIMKHDIELVKQISNQCSSFSGIVIGLLNSDGTIDKCNTEKLVELASPLSVTFHRAFDMTRDYIESFNTLNSINCSTSNNNNNNNSGGGCGKISRILTSGMESSVLEGIDTIKELIKLSNGTDITILPGGGITQKNINKIIKKTKLKEYHISARTVSDSKMQFRNTSVFMGGSLRESEYTYAIVDKNKIQGFINKSNTN
Involved in copper homeostasis.
Q54VK3
INT8_DICDI
Integrator complex subunit 8-like protein
MNKIFGVKIDSQQKKRQQSNKNLTVFNNGRYLIYIGDIHFDRKFHREALRYYLLGCGLETAFYSDPVKTSVTNSKYLTFLSRRIFDCFYFLRAPMQAIVVSQFFGNLNQTCLVSFKIIQEEYYQLDTNYFQYIWELPLLEILLTTFTKQKDLKKIYLINQIISNPIINENNHPDIRKNFIKNTKHNFWKAISSNYLLQ
May be a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
Q552Q3
INT10_DICDI
Integrator complex subunit 10-like protein
MMVDNEEINSLSIENILERINKSSNINEAKSLCLFASSLFDNNQYLLIQRYLISIKERDFDISIQLFWRLFNNNSFKEYIVLVVLKFLEKEIEDLEYYDFIKKNYRDQFQKIFIDSDDNSTNNSSSSSNENKKNKRSYLKLNTILNKLTKSLNHLSFYISEIDNLNKFFNPITFLLNNNNNNNNNNNNNNNNNNNKNNSNNNNKNNNNNNDDSNNNNNNNFLKILELIQKSCQYLNENENYEYSILLYLLIKGKFENKIRTFIKSSKKEDQDIKSKIKRFWFNGIQSLNQYKNKYSSKIEIEPPLPMKSYFDEDDYDQKQQQQQQQQQQQQEQKGSKEDEEDIEKQKKSLTSEIELFLLPINRFCLPIIFHIENEEFEQLDIKGNSGSGSDSSSSISKLEIVDQCWKYYICKGDDITDESILEIQKFLQQFADSGKHLKRHQNNSILNFTINLLSNPEKARNDYFDRNSEGNGGDENDENSQESNDSYEFEIHLGIYLLSSLLYISSWRYFKFLVTGSSNIEKQNIQTIGTLKKNQILLFDANFNSNSNSSSGSNGIINNNSNSNQQSYHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQGQQPNLSMITHQVLYYSNVDDESSFDDEFPKIVFTKQQTEAIKHLTLCMECFNDLNQEPWINDFKRILSTTWNNSKFYWLYNSLADSHYYYKLDGANTLIPIGDSKKRLFNPNDELWFNRLLLNIGMTNHSEIEDSIICLLEILISISIPPPPSSSSSSFSSSNSSLNNDLFNQQLVPSKHTFKTIKPYLTVFSEEEILFWCIDTLATCYERLGMVGEITVLYQAYWNYYKSRFYQIINEIKGTPNQNPNLIPLSNLVKKDLQIGYFFPRFFDYIINIEMLEEFCFILNKGFKLDILQRNQTVSSNREMIDIIKRHITITTSNNNLTIPILLKQFFNEELDHFLIKKENREKQYSSSNTANNSGVNNSPIHNQNTDVEMNE
May be a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
Q55785
YIDD_SYNY3
Putative membrane protein insertion efficiency factor
MMKKLLLTLIKLYRILISPLFPPSCRFQPTCSQYALDAVEIHGVWRGSCLALKRILRCHPLHPGGYDPVPNPEQGKISS
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q55G88
PSMG3_DICDI
Proteasome assembly chaperone 3
MNSLLIDSSNPSYDAMNNDNLKNSIEKNHPVKSKVLSKKINNVDTDIAISSFADAIFITISQNQKFNTWIRASKSDGILLDEPSYQIDTLLGNNQDVLFSIYARQLIENIGETSNKSLMLSISITDKSKDTFKQILSTIFENKVW
Chaperone protein which promotes assembly of the 20S proteasome. May cooperate with psmg1-psmg2 heterodimers to orchestrate the correct assembly of proteasomes (By similarity).
Q56585
BOLA_VIBAL
DNA-binding transcriptional regulator BolA
MIQEIIEKKLHSELQPSYLKVINESYMHNVPPGSESHFKVIVVSDSFAGQRLIGRHRQVHQILADELDNHIHALAIHTYTDEEWKREQDGAPDSPMCMGGGH
Transcriptional regulator that plays an important role in general stress response.
Q56888
FLHE_YEREN
Flagellar protein FlhE
MLTCLSRRVLVGLFSIGILPLNAMASGSWVADDIGITQSVRGVAISAKPLQSPVALAQDNARIVSISWRYQLMSAAPDGLQVKLCTPTRCMPLEGGSGLSRGLAGEAAATQLTFIYFIAGKGRVNPPLQVINHQVIVNYR
Not essential for flagellar formation and function.
Q56897
TRA8_YEREN
Transposase for insertion sequence element IS1328
MPNVTLIGIDLGKNSFHIHCQEKHGNTLLRKRFSRIQLTQFLATCPPCIVAMESCAGAHFMARHISQLGHQVKLISPQFVRPFVKSNKNDFIDAEAICEATSRPSMHFVTPRTEDQQAMSALHRVRDALVRERVKATNQMHAFLLEFGISMPRGIAVIKRLATVPEEHELPPYLVRLLTRLHQHYGYLCEQIEEIERELKNHLADDETAQRLLTIPGIGTITASLLATKLGDGKNYLSSRDFGASTGLVPRQYSTGGKSTLMGISKRGDKNLRRLLVQCARVYMQRLEYQSGRLAEWVNGQLTRHHSNVVACALANKLARIAWVVTTQGTVFSK
Required for the transposition of the insertion element.
Q57194
TUSC_HAEIN
Protein TusC homolog
MKIAFLFRTSPHGTSISREGLDAILAATAFCEPNDIGIFFIDDGVLNLIDNQQPEIIQQKDFIRTFKLLDLYDVEQRFICTASLQKFKLDNRELILSCEKIDRSLLLEKLNQAGKLFTF
Could be part of a sulfur-relay system.
Q57607
Y142_METJA
Putative toxin MJ0142 (UPF0332 protein MJ0142)
MRLKIMELRYKRELEKLIEKAEKSLEASENLYNSEFYDFAVSRIYYSMFYCVKALLLTKEINPKKHSGVLKMFAKEFIKTNELDVELFEYINEAYNYRQTADYDATIEIKKEEAEYLLHKGHIFLNKTKKYLISKNILKGENDNTKS
Putative toxin component of a putative type VII toxin-antitoxin (TA) system. Its cognate antitoxin might be MJ0141.
Q576D4
LIVB5_BRUAB
Leu/Ile/Val-binding protein homolog 5
MIGTRLPAWTRVLACGVAGLSLMTISAKAEDVITLGASVQLSGPVANTGRYYQDAYNITIDKINAAGGVKVDGKPYKLALKIYDNQSNVNLSVRQYTQLVTTDKVNFLLGPFASNFALADSVISEKYRIPMVQGGGASDEIYSRNFKYIFGTLAPASNYFGSTVEMLKGLDPKVTNVALVYADDSFDVSVADGTRKLLKDAGFTIAADEKFATNSTDFTSLISQIKSKNVDAVLVAGHETEVLNFVRQSKSLAFDPKLYSFTVGVPTEDFRKALGKDANYAFGMTAWLPSADLKDRWFGDAAKFETEYKARFNYEPDYHAASGASDVEAFAEAIEKANSLDPQKVRDALASIKFDSLYGPIAFDKQGQINLPQIVVQVQDGKLVEIRGPAGQVNPPQYPMPAWNAR
Component of an amino-acid transport system.
Q577C7
NRDI_BRUAB
Protein NrdI
MSLIVYFSSRSGNTHRFVERLGVRSSRIPLEASGALQVREPFVLVTPTYGGGSTKGAVPNPVIRFLNDADNRALIRGVIAAGNSNFGEAFCIAGNIISAKCGVPYLYRFELLGTAEDVGNVRNGMEQFWTRQTQA
Probably involved in ribonucleotide reductase function. {ECO:0000255|HAMAP-Rule:MF_00128}.
Q577I2
LIVB8_BRUAB
Leu/Ile/Val-binding protein homolog 8
MRLSRLLIGASLGVALSSTVFTAALADVKFGSLYPISGSLALLGEESARGLELAVDEVNAAGGIKGEKVVLERGDAVDNNQATGEARRLISLVGVKAIFGTYSSARVIAASQVSELAGIPYFEMGAVADEVTGRGLQYLFRTNPTAENMAKDSVDMLIKGIAPGLGKDPKDMKIGIIYEDSSYGTSVAGHQEDNAKAAGLTVVLKSGYPSNTVDMSSLVLELREKGADVVMQTSYQNDSVLFLQQANEAGYKPLAIIGGGGGYSMQPTADAVGHDLIDGVFDADYTQYAVNTSATPGLTEFVEAYKAKYGSQPRSGHSLTNYVGAKAIFQALNAGEGFEPDQIVSAVKALDIPDGQTAAGYGVKFGKNNQNERATMMGMQWQDGKLVTVYPENAAIAKMRFKK
Component of an amino-acid transport system.
Q57824
CSA3_METJA
CRISPR locus-related putative DNA-binding protein Csa3
MVRYMRYIATFGYHTNHIFDKNGKIIGIDDEKISNMILIYSLDVDADENTVNSIKNTKNYIESKLKEYNIPYLFVEVNPYEFNTNVKNFRKYIVPKTIINLTGGKRIVGYALFYAAVLEKENVEKVFYVSKLGDIIEFPLIPPDIKLTELEMKILNLLDKEGEMSVSNIAHKLERSLSTISEYVSQLEKKGLVKKLSKGRRKIVKKVI
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
Q57827
CAS5_METJA
CRISPR-associated protein Cas5
MIMEALVALLRFPFYSFGKQSYQVRQSLLLPSPSALKGALAKGIILLGGKKGKSLDEIAKKTVEELENKLIYVGAKPYKSSIIKTPILLKRLRNLEDQKNPEKSDAMRREYVFAREILAIYVFRRKLSEEEKDLMLKAVYLIDQLGDTECVGNVIKTEWVEVKEEKAPLKTYVKFKKVSKMSINGGIIENMLETPNFGNKVKEEPYLLPLIEKRYRRSSYYVESDRIFDGNYKIIAFDEVIGLWI
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
Q57830
CAS8A_METJA
CRISPR-associated protein Cas8a2/Csa4 (CRISPR-associated protein Cas8a2/Csa4, subtype I-A/Apern)
MIIKGLRVEKEKLQSLQKFWRLRVMLFETPGYNEILDLYIAYGVVECLVREGVENLRFFPIGNKYCIVVEEPTNVNIKNRIEKGMLNALEDMLSLHKAIGKYISTKEDIKIISDVDFSAGANINNVYWDGIPKTLEKIKENIKKGKLSTKSKNTVPLTLMPAAGKYMPKIYGVKGGNPIKIDDSNYALAWIGFHYYAPYINISDNRATYIHIYAIKPLEELGLIEILALKDLKKKINNYQLGKYKFFVNKKLALLYHLTHTESISALEIVTKKNFSVVSYTLENVDNNQAIRSFGEYDLSKLMDFLWYLKATDFYNTIQFVDNILRGDLEVSLTFIDGILYDDLDAVYSAIRKLKSVRISPLIIQSILEWFGNFY
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
Q578E0
LIVB6_BRUAB
Leu/Ile/Val-binding protein homolog 6
MKKIALTALAVFSLAASAAYADVVKVGVIGPFSGPFALQGKNFKAGIDAYMAEHGNKVGDDTVEVVYRDVPQADPAQSKALAQELVVKEGVQYLAGFYFTPDAMAVTPILKQGNVPMVVMNAATSSIVTKSPYVVRTSFTTWQTSTPIARVALDKGVKKVISVVSDYGPGVDAENAFKAAFTDAGGEVVEAIRMPLATNDFSPIMQRIKDSGAQGVFAFLPSGPTTFGFMKAYVDNGLKSSGIQLFAPGDLTQESDLPALGENALGVLTTFHYAVSHDSPENRKFVEEARKAIGNPAELSFPSVGAYDGMHVIYKMIEATGGKKDAAKAVEAVKGMEWVSPRGPVSIDPESRHITQNIYLREVAKADDGTYYNKEIQTFEKQGDPGLKAQ
Component of an amino-acid transport system.
Q57987
FEOA_METJA
Putative Fe(2+) transport protein A
MYPLAFAKEGEEVIVKKIDAGCGAMQRLVSMGINIGSKLKVIRNQNGPVIISTKGSNIAIGRGLAMKIMVEDAEYGGENEKL
Might be involved in Fe(2+) ion uptake (By similarity).
Q57B99
LIVB1_BRUAB
Leu/Ile/Val-binding protein homolog 1
MRKTLFSGVALAAVIAFGGSAWADVLVGIGIPVTGPNAVYGAQIQKGAEAAIKEVNDAGGINGEKIAITIGDDVSDPKQGISVANKFAADGVKFVIGHFNSGVTIPASQVYAENGILEISPGATNPQYTEQGLWNTFRTCGRDDQQGTVAGQYIFDHFKDAKIAVIHDKTPYGQGLADETKKKLNELGTKETLYEGVNVGEKDFSALIAKLKQAGVNVVYWGGMHPEAGLLIRQMADQGLKAQFISGDGIVSNELASIAGDAVAGVMNTFGPDPRDDKANAELIKAFRDKGFEPEAYTLYSYAAVQSLAQAAKAAGSNDPQEVAKAMKEKGPFKTVLGDLSYDEKGDPKLPGYVMYKWEKGADGKYNYIQQ
Component of an amino-acid transport system.
Q57BA1
LIVB2_BRUAB
Leu/Ile/Val-binding protein homolog 2
MKKSLFCGVCLCALVAMGGTSFADIMVGVGAPLTGSQAAFGEQIKRGVEAAVAEANAKGGMNGEQITLVYGDDAADPKQGISVANKFVGDGVKFVIGHFNSGVSIPTSDIYAENGVLMIAPGTTNPTFTERELWNTFRTCRRDDKQGIVPGKYMADNYKDGKVAILHDKTPYGQGLADETKKKLNELGTKETLYEGVNVGEKDFSALIAKLKQAGVNVVYWGGLHPEAGLIIRQMADQGLKAQFISGDGIVSNELASIAGPAVEGTLNTFGPDPRNNPDNAELVKKFRDAGFEPEAYTFYAYAGVQSLVNAANAAGSNDPMEVATAMKEKGPFKTVLGDISFDAKGDPSLSPYVMFEWRKGEDGKYNYFQK
Component of an amino-acid transport system.
Q57D63
YIDD_BRUAB
Putative membrane protein insertion efficiency factor
MGSCGGKHTGKGAPKPYSRNFTDPWRKTPGRLFGTALIRFYQITLSSLIGNSCRHLPTCSEYAYEAIARHGLWRGGWMGFFRVVRCGPFGTHGFDPVPRELSPDLKWYMPWRYWRCSASRIGK
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.
Q57HI2
FDHE_SALCH
Protein FdhE
MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKHWQKLLHSLIAELKPEMSGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQISTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE
Necessary for formate dehydrogenase activity. {ECO:0000255|HAMAP-Rule:MF_00611}.
Q57JR3
GLGS_SALCH
Surface composition regulator
MNNNNVYSLNNFDFLARSFARMQAEGRPVDIQAVTGNMDEEHRDWFCKRYALYCQQATQAKRLELEH
Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides. {ECO:0000255|HAMAP-Rule:MF_00525}.
Q57KF0
SYDP_SALCH
Protein Syd
MDELTAQALKAFTTRYCDAWQEKHGSWPLSEELYGVPSPCIISSTRDAVYWQPQPFEGEENVNAVERAFDIMVQPALHAFYTTQFAGDMPAQFADEKLTLLQTWSQDDFRRVQENLIGHLVTQKRLKLPPTLFIATQENELEVISVCNLSGEVIKETLGTRNRTVLAATLAEFLTQLNPLL
Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. {ECO:0000255|HAMAP-Rule:MF_01104}.
Q57KW6
NRDI_SALCH
Protein NrdI
MSALVYFSSSSENTHRFMQRLGLPATRIPLNERERIQVDEPYILVVPSYGGGGMAGAVPRQVIRFLNDEHNRARIRGVIASGNRNFGDAWGCAGDVIAQKCGVPWLYRFELMGTQRDIDNVRKGVNEFWQQLPRSA
Probably involved in ribonucleotide reductase function. {ECO:0000255|HAMAP-Rule:MF_00128}.
Q57QP3
CBPM_SALCH
Chaperone modulatory protein CbpM
MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNADWQFDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRLLLQRLSRFISHP
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ. {ECO:0000255|HAMAP-Rule:MF_01155}.
Q58012
BRIX_METJA
Probable Brix domain-containing ribosomal biogenesis protein
MILTTSRKPSQRTRSFARDLERTLNIPYVQRGKLSLKEIFEIDKHVLLIGEFKANPGTLVVYDVENEKRLSSFISVKLQREICGEKIYNDDGIRIKISRELKDNEEFQKYYEIYDEFLFQHLNINEDSDITLRLEKDPKYLFAIQFYKGRVKIGPLIRIKSIKLFDSLL
Probably involved in the biogenesis of the ribosome. {ECO:0000255|HAMAP-Rule:MF_00699}.
Q58022
Y605_METJA
Putative toxin MJ0605 (UPF0332 protein MJ0605)
MKALLNKDIREEIQALIEIAEENLSAAKILFENKLYRDAVARAYYAIFHSAKALLLTKNLNPKKHAGVIKMFGLYFVNEGYIEEIYGRIITKSYNLRWKADYTTDKPTEEEAESIIYEAEMFVDRIKKALKEIL
Putative toxin component of a putative type VII toxin-antitoxin (TA) system. Its cognate antitoxin might be MJ0604.
Q58319
RELE2_METJA
Putative toxin RelE2
MKQWKYLLKKSFIKDLKELPKNIQEKIKKLVFEEIPNKNNPPEIPNVKKLKGADSYYRIRVGDYRIGFKYENGKIVFYRVLHRKQIYKRFP
Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is RelB2 (Potential).
Q58385
VAPB2_METJA
Putative antitoxin MJ0975
MEIVVDAIYEKGVLKLKKSINLPEGCEVEIKIIPKKISEKTFGILKLSDKEIKEILEEIENGGE
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC2 (Potential).
Q58522
VAPB3_METJA
Putative antitoxin VapB3
MINMATITIDDDVYKELLKLKGRKSVSEFIKELLEERKRKNLDVFMIAFGSRSEEDVEKLKKELKEAEKWMQSLIQV
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC3 (Potential). {ECO:0000255|HAMAP-Rule:MF_00794}.
Q58572
RELB4_METJA
Putative antitoxin RelB4
MILMVKAIVDITDENNRIINIVKAKYNLRDKSQAINKIIEEYAEFLLEDELKPEYIEKIRNIMKNEKPIYIGSIENLKKRYLGE
Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is RelE4 (Potential).
Q58573
RELE4_METJA
Putative toxin RelE4
MYEIEIMPSLDKILQKLSKRDKKKLKAILKKMEEITQNPHHYKNLRHPLNDFKRVHIDKSFVLVFTVDENNKTVIFVDFDHHDNIYKKKKLFKD
Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is RelB4 (Potential).
Q58700
Y1304_METJA
Putative toxin MJ1304
MEDSGFNIKYAKLFIKRAEEDLEVAKVLLKTNHYPDSVYHSQQCVEKAVKAVLILNGIIFRRHVVSGVFRNVIYEMKIEDSWKEKLLNLIPKIESLEEHWVMPRYPEPYFGELWNPLEEYTKEDAEECLKDAENVLEVIKDFLKEKYGLKQI
Putative toxin component of a putative type VII toxin-antitoxin (TA) system. Its cognate antitoxin might be MJ1305.
Q58894
C2M5_METJA
Putative control protein C.MjaVP (C.MjaVP)
MSKSGNKNQNCPKCNNSPWIQRANNFIAQNQNVQTGTKEYYQVEAVKYLLNNGHCGIDCRAKISDIIKGINYPKNREAFQHEVLIPLKQYGIIATLVYPGRKGGVFIPCNNDEIKKVAKQVFKRIESELENLEGSATGVQNIKNLANSLKTTVHNLKNTI
May be involved in control of expression of the type II restriction enzyme MjaV and/or its methyltransferase M.MjaV.
Q59068
Y1674_METJA
CRISPR-associated protein MJ1674
MLKVLISPLGVGDTNTDVYKRQYKTAEYKFEGDIDGIESPFVLSVLIEKLKVDKVIVVGTAKSMWEKLYEYYAKEVGEFDEEYWIEIGKKVGMSKYDNYALSEEDLKKIEKVIDKYLKKINPNAVGGSKCKIIKYGIDKDEIWENFDLFMSLINEVNDGDEIYLDITHSFRSIPLFMYVMLEFMRYFKNVKLKGIYYGMLDVIRELGHAPVVDLSPIFEISEWIRGMYEFTTYGNSYLISKLLENEDKEIAEKLQKISRYIDANYLKELREEVKTLKPLLNEKKDTGRFLKYFIPELHKFIDKLKYEDSDFEFQISMAKWNFDNKKYSSGYLCLTDSIFWKLCELYNLPSVYKNREVMKGIIYNPSLNKKYSAFGSIKDMHYKRLRNIRNKIAHADVSKKGDDFNPENDLEDVVNLLKNVNLPDFDKIIEDLLLDVKNNQNNKTLKLLKNILNIQIIRKIIKAYNFESNEIYWDFVSGYLLNKNNKCNNEKLREIIEIFHKNIEDAGELEEAFNFVKNTEDEELLDSLALQNAIMHYALFKLSNAYNIKNKEDKEAIKWVLLNQNLCSKHPILKEINNNYHKIFKNKDKPMSNEILEASKNIIRLLNSDLSEIKDSVPLNLIIIRYRSYKNNRR
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The type III Csm effector complex binds crRNA and acts as a crRNA-guided RNase, DNase and cyclic oligoadenylate synthase binding of target RNA cognate to the crRNA is required for all activities.
Q59PT4
LCL2_CANAL
Long chronological lifespan protein 2
MFQKLIVITFAIALASANIFDFLNNFNTGGRQQQNQGVRTPQEYESVVLNSQCDKYLCPDTGLCVEAPKFCPCPYPSSQIRCFLPDGRFVCISKPAGEGISEKYNDPKTNWKIDAKDDNIRDCGWVNRAWRGLV
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
Q5AM50
NMD4_CANAL
Nonsense-mediated decay protein 4
MSLELSSNESEDNFRDELVDISGQVSKKPINIDSRQVRLILDHTAFVRGIGNIKRWFNEEYINSNTTRSNEIINLNIYIPTYTLHEFDFVKKGTSISATNAREAIRFIDNYLENEVEMNSDKIQYNLILESPQDNVPSWNKCNHYKVHSPKIKEFPNYKTKFDSSLIGQTPNVNEDSEFNENFDNALTFNQRNKLNDIQYENSASYQNAIANSDNLAEMPVRLRYLIRSCIYKRFIETKKPKIKNEIEDWKLVTEDPITKIWAKSYGIDCLNVNEAELLIFQNYDVNSFRLYNPYANDGDDFDPSTNILQNTIDTTLYSYSSVQDEPVTSNYRGKNNRGRNNRGRRGNKRRERERWPLSTDAVVSEERNESGTGFIKKEKFGAINYAPRGQGELWRPG
Involved in nonsense-mediated decay of mRNAs containing premature stop codons.
Q5E305
SDHE_ALIF1
FAD assembly factor SdhE
MYSAEEKARVKWACRRGMLELDVVIMPFFDECFEELTEAEQQAFVSLLECDDPDLFTWVMGHGRSDNLAHASMVDKIVEHNLSKLR
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q5E7A2
SYDP_ALIF1
Protein Syd
MPLSVEQALANFSQRYVEAWKAQHDCLPINEELVGLASPCIEETRDLEISWQPIVRDEAIRLHNIEQGIELDLHDDFHAFYGTQYSADMTAKFEDMNIELLQVWSDEDLERLQGNMLGHLVMQRRLKLVPTLFVAVTDDEMEVVSICNQSGEVILDRVGTKNRTVLAANMAEFLNKLEPVIAA
Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. {ECO:0000255|HAMAP-Rule:MF_01104}.
Q5E7T0
FETP_ALIF1
Probable Fe(2+)-trafficking protein
MSRTVFCVRLNKEADGLDFQLYPGELGKRIFDNISKEAWGQWQHKQTMLINEKKLNMMDPEHRKLLETEMEGFLFDGKDVVIDGYTPPSE
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.
Q5E8C2
TUSC_ALIF1
Protein TusC homolog
MNRLGFVFQSAPHSTSKGREGLDAILAASAYSEDIQIFFIGDGVLQLLKNQEPEKILSRDYISGFKMLELYDLEEIFVCQNAMGNRGIKEEYLLIDVDSISNKDINEKLSQCDQIMVF
Could be part of a sulfur-relay system.
Q5EF74
HRCA_ANASL
Heat-inducible transcription repressor HrcA
MQVQLTNRQQHILWATVRHYIATAEPVGSKALIEEYDLGVSSATIRNVMGVLEKSGLLYQPHTSAGRVPSDSGYRIYVDKLITPSEVLAKEVESALQQRLQWEDWSLEILLQGAAQILASLSGCISLITMPQTNTATVRHLQLMQIEAGRIMLILVTDNYETHSKLMDLPPGRSEKPDPEVIDRELQIVSNFLNSHLRGRSLLEITTLDWSQLDREFQLYGEFLKTSVAGLANRTAAPAATQIMVRGVAEVLRQPEFSQLQQVQTIIQLLEEEQEQLWRLIFEEPELEDTNKSKVTVRIGAENPLEPIRTCSLISSTYRRGAVPLGSVGSSRPSRLDYENAIAVVAAAADYLSEAFS
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.
Q5F4W4
YIDD_NEIG1
Putative membrane protein insertion efficiency factor
MNFLLSKLLLGLIRFYQYCISPLIPPRCRYTPTCSQYAVEAVKKYGAFKGLRLAIKRIARCHPFGGHGHDPVP
Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.