jonghyunlee/UniProt_function_text_descriptions

entry stringlengths 6 10	entry_name stringlengths 5 11	protein_name stringlengths 3 2.44k	sequence stringlengths 2 35.2k	function stringlengths 7 11k
Q5F553	FETP_NEIG1	Probable Fe(2+)-trafficking protein	MARMVFCVKLNKEAEGMKFPPLPNELGKRIFENVSQEAWAAWTRHQTMLINENRLSLADPRAREYLAQQMEQYFFGDGADAVQGYVPQ	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255\|HAMAP-Rule:MF_00686}.
Q5FRF2	HRCA_GLUOX	Heat-inducible transcription repressor HrcA	MMRPQPPLFRPSIPMPHGLGDREAAILREIVEEYVETGEPIGSQTLAQRLQPSLSPATIRNVMAELARAGLLFSPHVSAGRLPTEKGVRLFVDGLLQFSSLTEEDRASIDSRLDIHGRSYQDILSEASSLLSGLSSAAGLVLAPKSDATLKHIEFVALGPGRVLVILVGSDGQVENRIIETPPGVPPSALVEAGNYLNSRLGDLTLGNLRERVRAEMDASRHELDALTASVIESGLATWDADGGTLFVKGQGKLLADITEIERLTTIRMLFDHLETQETMLQLLQLADASEGVRIYIGRESGMFGMSGVSMIVAPARNEAQKIVGAIGVIGPTRLNYGRIVPVVDYTARMVGRLLG	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255\|HAMAP-Rule:MF_00081}.
Q5GY22	FETP_XANOR	Probable Fe(2+)-trafficking protein	MSRTVFCHYQQSDAEGLDFVPYPGELGQRIFAHIGKTAWQAWLAHQTMLINENRLSPRDPKHRAFLETELQKFLFERNADKPDGYVAPLGEE	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255\|HAMAP-Rule:MF_00686}.
Q5H0G1	SDHE_XANOR	FAD assembly factor SdhE	MQRHRPLGQVPLSFSARHTARWRDEMDEQTRLKKLRWRCRRGMRELDQLFGRYLDQRWAQAPDAERAVFLQLLDCEDDKLWRWFMGYEACPDVANAALIADIRALPA	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q5H188	HRCA_XANOR	Heat-inducible transcription repressor HrcA	MRASQSPMLDPRTRQLLRTLIARYIRDGEPVGSKTLAQHAGLDVSPATIRNILADLEDVGLLSSPHTSAGRVPTAHGYRVFVDSLVQMQPPGEEEVRRLRAELASGNGTQSLLGSASQMLSAMSHFVGVVSAPRREQFAFRHIDFVALDARRVLAILVFADNEVQNRVIEPRRAYEPAELERVANYLNAQFAGRALADIRACLLRELRMAKNEMEQLLAHSVDLASEALVPADADDMVMAGQTRLMGVQDLSDLDRLRELFEVFASKREILQLLERTIQAPGVRIFIGEETGMVSLEDVSLVTAPYTAHGQVLGVLGVIGPKRMAYDRLIPLVQTAADVLGAAMESPGTR	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255\|HAMAP-Rule:MF_00081}.
Q5HEI2	OMP7_STAAC	77 kDa membrane protein	MKFKSLITTTLALGVLASTGANFNNNEASAAAKPLDKSSSSLHHGYSKVHVPYAITVNGTSQNILSSLTFNKNQNISYKDLEDRVKSVLKSDRGISDIDLRLSKQAKYTVYFKNGTKKVIDLKAGIYTADLINTSEIKAININVDTKKQVEDKKKDKANYQVPYTITVNGTSQNILSNLTFNKNQNISYKDLEDKVKSVLESNRGITDVDLRLSKQAKYTVNFKNGTKKVIDLKSGIYTANLINSSDIKSININVDTKKHIENKAKRNYQVPYSINLNGTSTNILSNLSFSNKPWTNYKNLTSQIKSVLKHDRGISEQDLKYAKKAYYTVYFKNGGKRILQLNSKNYTANLVHAKDVKRIEITVKTGTKAKADRYVPYTIAVNGTSTPILSDLKFTGDPRVGYKDISKKVKSVLKHDRGIGERELKYAKKATYTVHFKNGTKKVININSNISQLNLLYVQDIKKIDIDVKTGTKAKADSYVPYTIAVNGTSTPILSKLKISNKQLISYKYLNDKVKSVLKSERGISDLDLKFAKQAKYTVYFKNGKKQVVNLKSDIFTPNLFSAKDIKKIDIDVKQYTKSKKNNKSNNVKFPVTINKFENIVSNEFVFYNASKITINDLSIKLKSAMANDQGITKHDIGLAERAVYKVYFKNGSSKYVDLKTEYKDERVFKATDIKKVDIELKF	Binds various plasma and ECM-proteins.
Q5HEY4	YIDD_STAAC	Putative membrane protein insertion efficiency factor	MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAFKGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5HFH8	HRCA_STAAC	Heat-inducible transcription repressor HrcA	MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFNNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLLNTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255\|HAMAP-Rule:MF_00081}.
Q5HFZ4	CVFC_STAAC	Conserved virulence factor C	MEILRIEPTPSPNTMKVVLSYTREDKLSNTYKKVEETQPRFINQLLSIDGITSIFHVMNFLAVDKAPKADWEVILPDIKAAFSDANKVLESVNEPQIDNHFGEIKAELLTFKGIPYQIKLTSADQELREQLPQTYVDHMTQAQTAHDNIVFMRKWLDLGNRYGNIQEVMDGVLEEVLATYPESQLPVLVKHALEENHATNNYHFYRHVSLDEYHATDNWKTRLRMLNHFPKPTFEDIPLLDLALSDEKVPVRRQAIVLLGMIESKEILPYLYKGLRDKSPAVRRTAGDCISDLGYPEALPEMVLLLDDPQKIVRWRAAMFIFDEGNAEQLPALKAHINDNAFEVKLQIEMAISRIENGDEALGSVWKQMANRTI	Required for hemolysin production.
Q5HFZ8	Y1460_STAAC	DegV domain-containing protein SACOL1460	MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVKTSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQASQMVDANVTVIDSKSISFGLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGNLMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSIGVAHANVIEYVDKLKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVVLKK	May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
Q5HG29	CVFB_STAAC	Conserved virulence factor B	MALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDDDELEVGEEYSFFIYPNRSGELFATQNMPDITKDKYDFAKVLKTDRDGARIDVGLPREVLVPWEDLPKVKSLWPQPGDYLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNEVIEAKPYRVLRIGSFLLSESGYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSFLPLAHERLDDDGQVIFDLLVEYDGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQKIINIETGKIALTKKGWSRMDSKE	Contributes to the expression of virulence factors and to pathogenicity. Involved in the production of hemolysin, DNase, protease and protein A (By similarity).
Q5HGJ6	Y1252_STAAC	UPF0122 protein SACOL1252	MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255\|HAMAP-Rule:MF_00245}.
Q5HHM6	EMP_STAAC	Extracellular matrix protein-binding protein emp	MKKKLLVLTMSTLFATQIMNSNHAKASVTESVDKKFVVPESGINKIIPAYDEFKNSPKVNVSNLTDNKNFVASEDKLNKIADSSAASKIVDKNFVVPESKLGNIVPEYKEINNRVNVATNNPASQQVDKHFVAKGPEVNRFITQNKVNHHFITTQTHYKKVITSYKSTHVHKHVNHAKDSINKHFIVKPSESPRYTHPSQSLIIKHHFAVPGYHAHKFVTPGHASIKINHFCVVPQINSFKVIPPYGHNSHRMHVPSFQNNTTATHQNAKVNKAYDYKYFYSYKVVKGVKKYFSFSQSNGYKIGKPSLNIKNVNYQYAVPSYSPTHYVPEFKGSLPAPRV	Adhesin that binds to the host cell extracellular matrix proteins fibronectin, fibrinogen, collagen, and vitronectin.
Q5HHS1	Y812_STAAC	DegV domain-containing protein SACOL0812	MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEIAIEEFYNKMASSQTIPTTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSYQAGEMVEGVNVHAFDSKLAAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYLIVDDLKNLQKSGRITGAQAWVGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFEDGQALYKKLQDDCPSAYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT	May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
Q5HHU1	NRDI_STAAC	Protein NrdI	MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY	Probably involved in ribonucleotide reductase function. {ECO:0000255\|HAMAP-Rule:MF_00128}.
Q5HIF2	CTSR_STAAC	Transcriptional regulator CtsR	MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY	Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Q5HIH8	SP5G_STAAC	Putative septation protein SpoVG	MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLFVAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVVPDKNATSEDSEEA	Could be involved in septation. {ECO:0000255\|HAMAP-Rule:MF_00819}.
Q5HIJ1	YABA_STAAC	Initiation-control protein YabA	MDRNEIFEKIMRLEMNVNQLSKETSELKALAVELVEENVALQLENDNLKKVLGNDEPTTIDTANSKPAKAVKKPLPSKDNLAILYGEGFHICKGELFGKHRHGEDCLFCLEVLSD	Involved in initiation control of chromosome replication. {ECO:0000255\|HAMAP-Rule:MF_01159}.
Q5HJ88	ESAB_STAAC	Type VII secretion system accessory factor EsaB	MNQHVKVTFDFTNYNYGTYDLAVPAYLPIKNLIALVLDSLDISIFDVNTQIKVMTKGQLLVENDRLIDYQIADGDILKLL	Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host.
Q5HNB4	YIDD_STAEQ	Putative membrane protein insertion efficiency factor	MKKILLSLVVFYQRFISPLTPPTCRFYPTCSQYTREAIEYHGALKGLYLGVRRILKCHPLHKGGFDPVPLKKDKNSKTTHHH	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5HPV5	Y802_STAEQ	UPF0122 protein SERP0802	MGQNDLVKTLRMNYLFDFYQSLLTNKQKNYLELFYLQDYSLSEIADTFEVSRQAVYDNIRRTGDLVEDYESKLRLYQRFEKRRELYNLMKQSLNQPELLKQYITQLEELE	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255\|HAMAP-Rule:MF_00245}.
Q5HRN1	CTSR_STAEQ	Transcriptional regulator CtsR	MHNMSDIIEQYIKRLFEEADEDVVEIQRAHIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQGYYVIDGLLDKGLINEREAKMIQTIIDRETLKMDVVARDIIRANILKRLLPVINYY	Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.
Q5HRR9	YABA_STAEQ	Initiation-control protein YabA	MNRNELFERLMKLEHHVEQLTTDMSELKDLTVELVEENVALQVENENLKRLMNKTEESVETHLDKDNYKHVKTPSPSKDNLAMLYREGFHICKGELFGKHRHGEDCLLCLNVLSD	Involved in initiation control of chromosome replication. {ECO:0000255\|HAMAP-Rule:MF_01159}.
Q5HUK0	YIDD_CAMJR	Putative membrane protein insertion efficiency factor	MICLKILRFYQKFLSPLKPAACRYYPSCSEYALWQFQKKNFFLAFFSTFFRVLRCNPFFKGGFDYPRVSKNFYPINLCFKPIFLAKKQLCFLYIPYKNKSFYLIKIIFKRTNQ	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5JDM5	BRIX_THEKO	Probable Brix domain-containing ribosomal biogenesis protein	MMLITTSHRPTRRTRSFGHDLEKVFPNSLYLTRGKKTIQDLLMEAYDRGYERLLIINVWKGNPLKMTFIKVDPEDWGYIGYLYLHGIKLQREIGFRNIPPIREEMPFVVTTAKRVGIDHTAFAQVFAELTGGKFVPRGNKSLQTIADKNNTDVIGVIENYPRGMAVNFYRFDITRERPVGPLILVKIWIMEDGRRWDYKEALGIKPKE	Probably involved in the biogenesis of the ribosome. {ECO:0000255\|HAMAP-Rule:MF_00699}.
Q5JDU6	Y1752_THEKO	Putative antitoxin TK1752	MGKTITIADDVYYELVKMKGKKSFSELLRELIGKKKKGNLDVLMIAFGTRTPEEVEELKKELKEVEEWMDSWTPASL	Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. {ECO:0000255\|HAMAP-Rule:MF_00794}.
Q5KVY7	YIDD_GEOKA	Putative membrane protein insertion efficiency factor	MGQWLIWCIRFYQRFLSPLKPPTCRFYPTCSNYGIEAIRRFGAIKGGWLTAKRILKCHPFHPGGFDPVPESSEHAKRNKIT	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5L0Q0	Y1195_GEOKA	UPF0122 protein GK1195	MLEKTMRMNYLYDFYQALLTPKQRNYMALYYLDDYSLGEIAEQYEVSRQAVYDNIRRTEAMLEQYEEKLGLLRKYERRRQIIERLKDYISRRYGADAELAALVRELDELD	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255\|HAMAP-Rule:MF_00245}.
Q5L300	LUTA_GEOKA	Lactate utilization protein A	MKVSLFVTCLIDLFYTEVGKATVELLERLGCKVDFPEAQTCCGQPAYNSGYVKEAKEAMKQMMRAFADADYVVTPSGSCAAMLKEYPHIFHGDPEWEAEAKRLAAKTYELTQFLVDVLKVEDVGASLHGRATYHTSCHMTRLLGVKDAPLRLLEHVKGLELVPLPNAHQCCGFGGTFSVKMGPISEQMVDEKIGHIEEAEADYLIGADCGCLLNIGGRIARLGKPIRVMHIAEVLNARN	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. {ECO:0000255\|HAMAP-Rule:MF_02105}.
Q5L302	LUTC_GEOKA	Lactate utilization protein C	MTRGAIHNRDAFLEHIAHRLGRAPRLSGVSRPQWSNQPQWKVLAGYSQDDLLNVLQKQCGLIHTDYIETTSAELAGALRRQVAAYGGGPVIVPDDPRFAEYGLSALLRDEWPAEQTTVHIWNPALGRQNIDAAEQANVGIAFSDITLAESGTVVLFSRNEQGRAIHFLPKTYIAIVPKSTVVPRMTQAAAVIHEQIEKGGLVPSCINFITGPSNSADIEMNLVVGVHGPMKAAYIVVTDR	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. {ECO:0000255\|HAMAP-Rule:MF_02104}.
Q5L3V1	SP5G_GEOKA	Putative septation protein SpoVG	MEVTDVRLRRVNTEGRMKAIASITLDNEFVVHDIRVIDGNNGLFVAMPSKRTPDGEFRDIAHPINSATRGKIQEAILAEYHRLGKLEEELEEAGAS	Could be involved in septation. {ECO:0000255\|HAMAP-Rule:MF_00819}.
Q5L6W5	YIDD_CHLAB	Putative membrane protein insertion efficiency factor	MSFKQLLYNLPTHLCCGLIHLYRWTISPLLGSPCRFFPSCSQYALQALKHHKCIRGLWLTIKRIGKCGPWHPGGIDLVPMTTLEEALDVSQVTNDDDSGDSHA	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5LJ21	YIDD_BACFN	Putative membrane protein insertion efficiency factor	MKRLLSYILLLPIYFYRACISPMTPPSCRFTPTCSQYAIEAIKKHGPFKGLYLAVRRILRCHPWGGSGYDPVP	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5M027	Y888_STRT1	UPF0122 protein str0888	MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEEFGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDDIMEKYADDSYLQEQIAILSSIDNRD	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255\|HAMAP-Rule:MF_00245}.
Q5M1H7	YIDD_STRT1	Putative membrane protein insertion efficiency factor	MMKKFLIALVKAYQRWISPLFPLSCRFCPTCSVYMIQAIEKHGLKGVLMGIARILRCHPLSETGDDPVPDYFSLKRKKTPLDN	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5M1U0	HRCA_STRT1	Heat-inducible transcription repressor HrcA	MITQRQNAILNLIVEMFTRTHEPVCSKALQDSIDSSSATIRNDMAKLEKMGYLEKAHISSGRMPSRAGFQYFVANSLNLDTIDEQDVYQVVKAFDFEAFKLEDILDAAAKLLAEMTGCTAVIQDVEPTKQRLTGFEIVQLSNHDALAVLTLDESKPVTVQFAIPKNFLSSDLEIFHKLVQGRFLGNTVLDIHYRLRTETPQIVQKYFKITDNVLDLFDYIFSHLFKELIFIEGKVASLAYADLKTYQFLDNPQHVALALRSAISDDEVTKISVAESTEEALENVTVMSHKFLIPYRGTALMHVIGPIEMDYRRMVSLVNVISRVLVMKLTDYYRYLNSNHYEVFLSRNVLKNIERGECLD	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255\|HAMAP-Rule:MF_00081}.
Q5M4P2	Y888_STRT2	UPF0122 protein stu0888	MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEEFGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDDIMEKYADDSYLQEQIAILSSIDNRD	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255\|HAMAP-Rule:MF_00245}.
Q5M619	YIDD_STRT2	Putative membrane protein insertion efficiency factor	MMKKFLIALVKAYQRWISPLFPLSCRFCPTCSVYMIQAIEKHGLKGVLMGIARILRCHPLSETGDDPVPDYFSLKRKKTPLDN	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5MGP9	DFP2_LONON	Defense protein 2 (DFP-2)	TGSGKYNILHNDNHNLDLTGKFLECSRSNPNLSDYNKYSAILDYLYKDKLSASLGVAHSGLLDRTDLSALGKVNLLNDKNTRLDLFGGLTKSMSPKFDSGLKPNFGLQLESSF	Has antibacterial activity against both Gram-positive and Gram-negative bacteria.
Q5MZ58	YIDD_SYNP6	Putative membrane protein insertion efficiency factor	MKLLLLALIQFYRRWISPLTPASCRFYPTCSQYGLEAIDRFGPLKGSWLTLCRILRCHPFHPGGYDPVPPLPSCSCGKSPCD	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5N3M2	HRCA_SYNP6	Heat-inducible transcription repressor HrcA	MLVSRLTARQQTILSATVRHYVRTAEPVGSKALAEQYGLSVSAATIRNAMGVLERAGLLYQPHTSAGRVPSEGGYRLYVDQLMEPDRALQRQTEQQLSQQLPDRRQSLEALLRGAAQILASLSGYLSLITFPLGLEFQVRHLQLVAIAPHQVLLIVVNDSYETQSALLTLPELDRDLEADQLDRQLLLLSNFLNQELQGRSLQALANLDWPVLGSELQSLAGILQQGLQDLEKRWQPTPATSLLVCGLADLLRQPEFNELQQVQALLELLEGEQTQLLPLMLADPAADQVRVRIGSELPLAPIRSCSLVSAFYCREQQPVGSVSLIGPTRMLYENAVAAVEATASYLSEAIAS	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255\|HAMAP-Rule:MF_00081}.
Q5NDN1	VSR_PNLV	Putative suppressor of silencing	MQNVNIPVGICNNRIVFRSLGFALSENNLTIEVLSRPIESLGRVLLFLYLYPSFAADYAQRYYGATWNQAYDISVRSLAFLLPFLFSPAVEWAVGPVFKSFVPLTELLKWSLAVGYYPTFPGSRQQLPSVPYDVNYGVQSTKAATVKLLRRAMLDDCIQSKTRLEAMLERGPDTFRNVLKAHISRIDRFTSSSGWHVADDYHMDLVLDISSGISRPSVHDNISFIQRSMRRISDILYDLCVPAHFLDLWRFTGLQCFWIDPNLGKF	Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
Q5NFS4	SDHE_FRATT	FAD assembly factor SdhE	MLIKNNDLIFSSVDKIKYSARRGMLELDIILAPYLNNCYMHEDLANKKLFVEFLTSEDSDMFDWLFKGVTPPQRYQQLIDKIIKEKKKFNQTKLK	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q5NHJ8	FETP_FRATT	Probable Fe(2+)-trafficking protein	MTKVFCKKYHQELDAIPFQPLPGELGKKIHNEISNKAWQAWLAHQTILINEYRLNLIEPKAKEFLKEEMHKFLFEGKEEKPEQFSEI	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255\|HAMAP-Rule:MF_00686}.
Q5NI55	YIDD_FRATT	Putative membrane protein insertion efficiency factor	MLINLYRYCISPFIPARCRYYPTCSEYALEALKTHGILKGLYLTTRRLLRCHPLSKRDYYDLVPCKNKKG	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5NVD7	ELMD1_PONAB	ELMO domain-containing protein 1	MKHFLRMLIQVCLYFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIEDIMELKKINPDVNPQLGISLQACLLQIVGYRNLIADVEKLRREPYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATAAQQVLSDSLHPKCSKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM	Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.
Q5P4P3	YIDD_AROAE	Putative membrane protein insertion efficiency factor	MKALVLGLLRVYRYAISPMLGRNCRFHPCCSEYAQEAVERHGAMRGGWLALKRVGRCHPFHPGGYDPVP	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5PC89	GLGS_SALPA	Surface composition regulator	MNNNNVYSLNNFDFLARSFARMQAEGRPVDIQAVTGNMDEEHRDWFCKRYALYCQQATQAKKLELEH	Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides. {ECO:0000255\|HAMAP-Rule:MF_00525}.
Q5PEK1	SYDP_SALPA	Protein Syd	MDELTAQALKAFTTRYCDAWQEKHGSWPLSEELYGVPSPCIISSTRDAVYWQPQPFEGEENVNAVERAFDIMVQPALHAFYTTQFAGDMPAQFADEKLTLLQTWSQDDFRRVQENLIGHLVTQKRLKLPPTLFIATQENELEVISVCNLSGEVIKETLGTRNRTVLAATLAEFLTQLNPLL	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. {ECO:0000255\|HAMAP-Rule:MF_01104}.
Q5PF04	NRDI_SALPA	Protein NrdI	MSALVYFSSSSENTHRFMQRLGLPATRIPLNERERIRVDEPYILVVPSYGGGGMAGAVPRQVIRFLNDEHNRARIRGVIASGNRNFGDAWGCAGDVIAQKYGVPWLYRFELMGTQRDIDNVRRGVNEFWQQLPRSA	Probably involved in ribonucleotide reductase function. {ECO:0000255\|HAMAP-Rule:MF_00128}.
Q5PGA1	CBPM_SALPA	Chaperone modulatory protein CbpM	MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNTDWQFDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRLLLQRLSRFISHP	Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ. {ECO:0000255\|HAMAP-Rule:MF_01155}.
Q5PKF1	FDHE_SALPA	Protein FdhE	MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKHWQKLLHSLIAELKPEMNGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIDTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE	Necessary for formate dehydrogenase activity. {ECO:0000255\|HAMAP-Rule:MF_00611}.
Q5PKU3	YIDD_SALPA	Putative membrane protein insertion efficiency factor	MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5PPV3	MORN3_XENLA	MORN repeat-containing protein 3	MPLVKAPKKAEPIWKEWDAKAQKAGLRHSVYSVNGDEYTGEWLNNLRHGKGTYMWKRRKSIYEGDWKCGERSGFGTYSVQDSNTGEYIKVYSGYWDNDKKHGYGTHFYSAKEYYEGEWKCGKRCGWGRMYFANGDIYEGEWLEDKHSGQGMLCLANENRYEGSWKDGKKHGPGKFYYLNKGQLYEGVWVEDIPKCGTMVDFGRTEAPYPTKYPLPEVKVADPEGVLKEAQQPLFGEHE	Assembles a suppression complex (suppresome) by tethering SIRT1 and MDM2 to regulate composite modifications of p53/TP53. Confers both deacetylation-mediated functional inactivation, by SIRT1, and ubiquitination-dependent degradation, by MDM2, of p53/TP53, promoting a proliferative and cell survival behaviors (By similarity). May play a role in the regulation of spermatogenesis (By similarity).
Q5PQ44	CF299_XENLA	Cilia- and flagella-associated protein 299	MEQSEAGSAADSIITQFNTYEDFLDSQITALDLHYLEDEELARQLVELGYRGSGEVLKRDEFEARKAAAEASRLSQRTQQKTLSSAGKDPKDNFLKALAMREEANRNGKMTSVIFIRDKNAHGQEVSGYIDFAHRLKTEDFEVYFSGKKKLLPRPTDLSFYNWESHVSTSNPSPNYQVIAETSSGLLFKNKRDRKILNVDPKASPGDNSTRTSIQTDIYIQAVIYDHITRRKS	May be involved in spermatogenesis.
Q5QW09	SYDP_IDILO	Protein Syd	MKTLEESIDALMTRYKENVPVRYTEYVEEWNSPIYGTVIDENTVEWTPCRQPEALNFDDLESALEMSFHQSIKTLFGRWYAGDLALDYQGHTISLLQTQSAEDGERLLENITGHILMKRRLKQPETVFIGLGSEDDGLLVTIDNQSGAVGLEWVGKEQHDVLSDSLAAWLDNCQPQVETDKNS	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. {ECO:0000255\|HAMAP-Rule:MF_01104}.
Q5QY58	FETP_IDILO	Probable Fe(2+)-trafficking protein	MSRTVFCEHFQKEAEGLDFQLYPGELGERIFNHISKDAWAEWQKKQTMLINEKRLNMMDPTDREFLEKQMTAFLFEGKAPEIEGYTPPES	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255\|HAMAP-Rule:MF_00686}.
Q5R0Z7	SDHE_IDILO	FAD assembly factor SdhE	MLPLKQSEEALKDKRRLRWACRRGMLELDVLFEPFVDQAYDELSEEQKAVFRRLITCDDPDLFAWFMGHQKCEDEELAEMIRFMLSRVKV	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q5R796	FBX36_PONAB	F-box only protein 36	MASWLPETLFETVGQGPPPSKDYYQLLVTRSQVIYRWWKISLRSEYRSTKPGEAKETHEDFLENSHLQGQTALIFGARILDYVINLCKGKFDFLERLSDDLLLNIISYLDLEDIARLCQTSHRFAKLCMSDKLWEQIVQSTCDTITPDVRALAEDTGWRQLFFTNKLQLQRQLRKRKQKYGNLREKQP	Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Q5R8D4	AVPI1_PONAB	Arginine vasopressin-induced protein 1 (AVP-induced protein 1)	MGTPASVVSEPPPWQAPTEARGRKQASANIFQDAELLQIQGLFQRSGDQLAEERAQIIWECAGDHHVAEALKRLRRKRPPRQKPLGHSLHHCSRLRILEPHSPLADPQSATETASTEQYLHSRRKSARIRRNWKKPGPTSYLHQIRH	May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.
Q5RBE4	DEPP_PONAB	Protein DEPP	MRSRLLLSVAHLPTIRETTEEMLLGGPGQEPPPSPSLDDYVRSISRLAQPTSVLDKATAQGQPRPPHRPAQACRKGRPAVSLRDITARFSGQQPTLPMADTVDPLDWLFGESQEKQPSQRDLPRRTGPSAGLWGPHRQMDSSKPMGAPRGRLCEARMPGHSLARPPQDGQQSSDLRSWTFGQSAQAMASRHRPRPSSVLRTLYSHLPVIHEL	May play a role in autophagy.
Q5RCY5	ASTE1_PONAB	Protein asteroid homolog 1	MGIRGLMSFVEDHSNEFFTDLKLRDTKIVIDGYALFHRLCFSSNLDLRYGGDYDSFADVVQKFFESLFACNICPYVVLDGGCDISDKKLTTLKDRAREKIQMAHSLSVGGSGYVCPLLIREVFIQVLIKLRVCFVQCFSEADRDIMTLANHWNCPVLSSDSDFCIFDLKTGFCPLNSFQWRNMDTIKGTQNYIPAKCFSLDAFCHHFSNMNKALLPLFAVLCGNDHVNLPIMETFLSKARLPLGATSSKGRRHHRILGLLNWLSHFANPTEALDNVLKYLPKKDRENVKELLCCSMEEYQQSQVKLQDFFQCGTYVCPDALNLGLPEWVLVALAKGQLSPFISDALVLRRTILPTQVENMQQPNAHRISQPIRQIIYGLLLNASPHLDKTSWNALPPQPLAFSEVERINKNIRTSIIDAVELAKDHSDLSRLTELSLRRRQMLLLETLKVKQTILEPIPTSLKLPIAVSCYWLQHTETKAKLHHLQSLLLTMLVGPLIAIINSPGKEELQEDGAKMLYAEFQRVKAQTRLGTRLDLDTAHIFCQWQSCLQMGMYLNQLLPTPLPEPDLTRLYSGSLVHGLCQQLLASTSVESLLSICPEAKQLYEYLFNATRSYAPAEIFLPKGRSNSKKKRQKKQNTSCSKNRGRTTAHTKCWYEGNNRFGLLMVENLEEHSEASNIE	Possible role in EGF receptor signaling.
Q5RD58	CL004_PONAB	Protein C12orf4 homolog	MKKNRERFCNREREFVYKFKVGSQCLELRVPLRFPVQENASHLHGRLMLLHSLPCFIEKDLKEALTQFIEEESLSDYDRDAEASLEAVKSGEVDLHQLASTWAKAYAETTLEHARPEEPSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELIGERDVELKKLRERQGIEMEKVMQELGKSLTDQDVNSLAAQHFESQQDLENKWSNELKQSTAIQKQEYQEWVIKLHQDLKNPNNSSLSEEIKVQPSQFRESVEAIGRIYEEQRKLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRNHRSGVKLHRLQTALSLYSTSLCGLVLLVDNRINSYSGIKRDFATVCQECTDFHFPRIEEQLEVVQQVVLYARTQRRSKLKESLDSGNQNGGNDDKTKNAERNYLNVLPGEFYITRHSNLSEIHVAFHLCVDDHVKSGNITARDPAIMGLRNILKVCCTHDITTISIPLLLVHDMSEEMTIPWCLRRAELVFKCVKGFMMEMASWDGGISRTVQFLVPQSISEEMFYQLSNMLPQIFRVSSTLTLTSKH	Plays a role in mast cell degranulation.
Q5REM2	L10K_PONAB	Leydig cell tumor 10 kDa protein homolog	MAQGQRKFQARKPAKSKTAATASEKNRGPRKGGRVIAPKKARVVQQQKLKKNLEVGIRKKIEHDVVMKASSSLPKRLALLKAPAKKKGAAAATSSKTPS	May have a potential role in hypercalcemia of malignancy.
Q5RFN8	TM101_PONAB	Transmembrane protein 101	MASKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMIQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHNTRRVEFWNQMKLLGESVGIFGTAVILATDG	May activate NF-kappa-B signaling pathways.
Q5SL49	YIDD_THET8	Putative membrane protein insertion efficiency factor	MREVLILLIRFYRRFLSPLKPRTCRFHPTCSAYALEALERHGAFWGSYLAVRRVLRCHPWNPGGLDPVPVLFPPGKVRGGAE	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5UQD7	SUI1_MIMIV	Protein translation factor SUI1 homolog	MLNRIIYDPFNDGLDTEQHFEKIHIKTKQRTKTKSITIIENIPEKIDLKLFLKKLKYTFHCSGSIQQNYDDDSKFIQLSGDHRELVKNFLIKNSIVKESNIVMHGY	Additional factor that functions in concert with eIF-2 and the initiator tRNA in directing the ribosome to the proper start site of translation.
Q5WF19	YIDD_ALKCK	Putative membrane protein insertion efficiency factor	MRKLLIQIIRLYQRFISPLTPPSCRFYPTCSAYGIEAIETHGAIKGSYLAIKRILKCHPFHPGGVDPVPECQHTKHKKTP	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5WFN0	Y2295_ALKCK	UPF0122 protein ABC2295	MLDKTLRMNYLFDFYHSLLTEKQRNYMSYYYLDDLSLGEIADEYDVSRQAVYDNIRRTEAMLEEYEQKLRLLEKFETRRSLLAELRKAIASDQAVEACNSLIDRIEKLD	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255\|HAMAP-Rule:MF_00245}.
Q5WJD9	LUTC_ALKCK	Lactate utilization protein C	MIKNRDSFLDHVANQLGRPRQTEGVLRPNYRVSPQFEVLKDASKDELVTVLKEQCVAIHTDFKQVESGQLETALDETIDMYGAKSVIAWDDRRFHEFGLGSFLTRPSVSLWDNRDSKRSIEQAEIADVGITFSDITLAESGTVTLFSSNGKGRSVSLLPRYYIAIIPKSTLVARMTQAARHIRQLTGEGRLPSCINFISGPSNSADIEMSLVVGVHGPLKACYIVVDDK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. {ECO:0000255\|HAMAP-Rule:MF_02104}.
Q5WJE1	LUTA_ALKCK	Lactate utilization protein A	MNVSLFVTCLADIFYPGVGKDTVEVLERHGCNVKFPENQICCGQPAFNSGYHEDTKKAAKHTIETFADADYVVLPSGSCAAMLLEYKELFADDPEWEKRAEELASKTYELTQFLVRVLKVEDIGAVCHKKATYHTSCHMSRLLRETEAPFSLLEQVKGLELAPLANKESCCGFGGTFSVKMPAISEQMVEEKVGHIEATGADLLIGADCGCLMNIGGRIERNGKTIEVKHIAQVLNSKE	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. {ECO:0000255\|HAMAP-Rule:MF_02105}.
Q5WQ00	REPA1_BUCCC	Probable replication-associated protein repA1	MFKRKKYVDNPYPKFVQPKNHKKRPAFIRYAMRCAAQTDVARNELYYTNPLKNPITGCVLHRKRRLNEHRARALRAVVQAMLYYFNIASMLVMASVEKLSDVCGLSTYSSAGNKSITRASRLITQFMEPMGLISCEKIWDKILGMYIPKIIYLKPLFFMLFDISKIRLKRVRIKQLEWINSQLKKKGEYPITLLEIEKQAKEKHIHSALLFRKSKYIIKKQKNKAKKFLELDEKYAKSYILNNLVKKYSTKELCKLGLTKLKRKVNCEYFRLKKLAQLPVV	This protein is essential for plasmid replication it is involved in copy control functions.
Q5WSE8	YIDD_LEGPL	Putative membrane protein insertion efficiency factor	MGKINLMLRQIVCLPIKMYQYFISPLITPCCRYYPSCSEYADSAIKHYGVIKGLLMALNRLSRCHPWSKGGYDPLFPNDKN	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5WVC4	FETP_LEGPL	Probable Fe(2+)-trafficking protein	MSRTVFCCKLKQEAEGLEKQPFPGELGKKVFNEVSKQAWNMWLSHQTMLINEYRLNLIEARAREFLKEEMQKYFFGEGSDKPSGYKEIK	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255\|HAMAP-Rule:MF_00686}.
Q5WWK6	SDHE_LEGPL	FAD assembly factor SdhE	MDNREKSRLLWKCRRGMLELDLVLQKFIANEIDRLTENQLKAFDNLLTHNDPNLYAWLMGHEEPEKELLEIVSFIRNCD	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q5X0M1	YIDD_LEGPA	Putative membrane protein insertion efficiency factor	MGKISLMLRQIVCLPIKMYQYFISPLITPCCRYYPSCSEYADSAIKHYGVIKGLLMALNRLSRCHPWSKGGYDPLFPNDKN	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5X3X9	FETP_LEGPA	Probable Fe(2+)-trafficking protein	MSRTVFCCKLKQEAEGLEKQPFPGELGKKVFNEVSKQAWNMWLSHQTMLINEYRLNLIEARAREFLKEEMQKYFFGEGSEKPSGYKEIK	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255\|HAMAP-Rule:MF_00686}.
Q5X4Y4	SDHE_LEGPA	FAD assembly factor SdhE	MDNREKSRLLWKCRRGMLELDLLLQKFIANEIDRLTENQLKAFDNLLTHNDPSLYAWLMGHEEPEKELLEIVSFIRNCD	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q5X9X0	Y1658_STRP6	DegV domain-containing protein M6_Spy1658	MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNRISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALMARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLRTYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEMVAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTLAVFVIGQNSR	May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
Q5XAD4	HRCA_STRP6	Heat-inducible transcription repressor HrcA	MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDMAKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKTFDFEAFKLEDMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQFAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFDYVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADSQEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYRYLNSNHYEVH	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255\|HAMAP-Rule:MF_00081}.
Q5XAI8	Y1140_STRP6	DegV domain-containing protein M6_Spy1440	MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDGLDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKNELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIFVLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEEIQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLMGYEI	May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
Q5XC23	Y905_STRP6	UPF0122 protein M6_Spy0905	MNTMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEKISILTSIDNRE	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255\|HAMAP-Rule:MF_00245}.
Q5XCN8	Y690_STRP6	DegV domain-containing protein M6_Spy0690	MKLAVITDSTATLPIDLKQDKAIFSLDIPVIIDDETYFEGRNLSIDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDRTTAFIMVDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPRL	May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
Q5XDK5	NRDI_STRP6	Protein NrdI	MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYLLIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQKLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHTSH	Probably involved in ribonucleotide reductase function. {ECO:0000255\|HAMAP-Rule:MF_00128}.
Q5XDL8	YABA_STRP6	Initiation-control protein YabA	MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLENTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRELLDRK	Involved in initiation control of chromosome replication. {ECO:0000255\|HAMAP-Rule:MF_01159}.
Q5XDP1	YIDD_STRP6	Putative membrane protein insertion efficiency factor	MKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGTKGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5YMR8	YIDD_NOCFA	Putative membrane protein insertion efficiency factor	MRSAAAALHRLPARALIFLIELYRTYVSPTRMPVCRFTPTCSEYAVTALRTRGLVVGLGLTAVRLAKCAPWHPGGWDPVPQRRPRRRDAAAADAAMSAPHACKGSPHAVVGDTNDGST	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5YZX1	HRCA_NOCFA	Heat-inducible transcription repressor HrcA	MGPMSSSTEDRRFEVLRAIVADYVATKEPIGSKTLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRIPTDKGYRQFVDRISEVKPLSAAERRAILQFLESGVDLDDVLRRGVRLLAQLTRQVAVVQYPTVSASTVRHIEVVALNPARLLLVVITDTGRVDQRIVELGAVVDDDDLSALRALLGAAMDGKRLAAASAAVAELPESAPQQLRDVLIRVSTVLVETLVEHPEERLVLGGTANLTRNAADFGLPGSLRQVLEALEEQVVVLKLLAAAQQPGTVTVRIGEETQVEEMRSASVVTTGYGVSGSVLGGMGVLGPTRMDYPGTIASVATVARYIGEVLAER	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255\|HAMAP-Rule:MF_00081}.
Q5ZJ37	RABEK_CHICK	Rab9 effector protein with kelch motifs	MGPRVLPLLEPGCRPQAGKWYRMAPRGEWPRGRVGHGCLFVPGGSGRVLLLGGADPAGAFADAHFVELGAHLWAPAAWSGLRPRYEHATFLSACRPPRLWVFGGAHRAGNRSCVQVLDPEIGTWESPEVTGIPPLPRTFHTSSAAIGDCLYVFGGGDKGAEPVKDQQLHVFDTVALAWTQPDTHGDPPSPRHGHVVVAVGTKLFIHGGLAGDIFYNDLFCIDTTDMKWVKIAATGDVPGGRASHSSAVFKDHLYIFGGIGPDGTLDTTYKYHIEEQQWTLLQFDSPLPAGRLDHAMCVIPWRVGKNGDAAAVSKEDKAEPTASAGDRAGHLCRGQDKKACTEDTMMHLLLIFGGMDTQAEIYRDCIVSLIE	Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
Q5ZL79	NOL11_CHICK	Nucleolar protein 11	MAALCEAFTLCGLGPAGGVGLGSGLLALEPGADPDHVLLTDRGRTTTLFKVSDQKPLGCWSVKHGQIITCPVVCNFETHEYIAVHDNKVLRIWKDEDVNLDKVFKATLSAEVYRIHSLPHAEPLVLFKGGGVRTLDVLLEAPQQEIENVISDEVIKWSEAFLESRQPVLIFVTEKDGDFFVYVQKPKMRSLHKYKLEQQELCNPLSFTAYIKKQIITLLCLYSSDSVYKVLIPLQQSSEEEEQTSSKSLLLNLSISGSVLKGTSFVVLDKDHVAVLGSLAASGEESKECLTIWNTKFQTLQASKELPLGTSGQLWCYGEKFFFTHGKVLTVVIYKCETSSLAAAVGKLKDSQTSDLSSFVNWNTLGDEELLVSLQSQQSVALKSESKMTLRSKKSAVANIQPDTSTVGQFLLSIKDASTAAVEDQLRQLLSKAQMPDFQATIGCIISALINRCKTDPKFYPRNFLVQMIQKGELSYSLCPDLMAVALEKKDVHLLQICLQRFPDIPEEITYACLKVFLSISDDYLERTDVNLESVISYIDIEPNNKEVKTEVVENGFNTELEEDGCDVTGMKETHMMDSVEFCPVGPQKAALLNAVLHSAYSETFLLPHLKDLPAQQAVLFLRYLHYLYVKCSEKINTTLPGILSPTISQIMDWMCLLLDAHFTVMVMLPEAKGLLSSMHRFVRAQVRLYSELNKIEGSLQELQRIKCQKHSQAYSIEVLELI	Ribosome biogenesis factor. May be required for both optimal rDNA transcription and pre-rRNA processing (By similarity).
Q5ZR80	YIDD_LEGPH	Putative membrane protein insertion efficiency factor	MGKISLMLRQIVCLPIKMYQYFISPLITPCCRYYPSCSEYADSAIKHYGVIKGLLMALNRLSRCHPWSKGGYDPLFPNDKN	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q5ZU80	FETP_LEGPH	Probable Fe(2+)-trafficking protein	MSRTVFCCKLKQEAEGLEKQPFPGELGKKVFNEVSKQAWNMWLSHQTMLINEYRLNLIEARAREFLKEEMQKYFFGEGSEKPSGYKEIK	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255\|HAMAP-Rule:MF_00686}.
Q60228	RELX_ECOLX	Putative RelE-like toxin protein	MRYQVKFREDALKEWQKLDKAIQQQFAKKLKKCCDNPHIPSAKLRGIKDCYKIKLRASGFRLVYQVIDEQLIIAVVAVGKRERSDVYNLASERMR	Toxic component of a type II toxin-antitoxin (TA) system.
Q60265	Y3531_METJA	Putative antitoxin MJECL31	MSEIIEVIYEDGVLKPLKPLKIKGKKRLKIKIVNDDVEEFLKSMIIKKCKDIDYKKLKEAYYESF	Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.
Q602M7	YIDD_METCA	Putative membrane protein insertion efficiency factor	MQRLLITLIRLYQYLLSPWLGHHCRFFPTCSNYAMDAIGRFGAMRGAYLTIRRLMRCHPWHPGGIDPVPEKLGKQ	Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255\|HAMAP-Rule:MF_00386}.
Q60373	RELB1_METJA	Putative antitoxin RelB1	MLNINKEIAQIETELNELKKLRDEISERIEKLEIKLLKLKALAIPEEEFEEDYEEIIEDVKKSLDKKETVPAEEALKELGLL	Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is RelE1 (Potential).
Q60374	RELE1_METJA	Putative toxin RelE1	MKFNVEIHKRVLKDLKDLPPSNLKKFKELIETLKTNPIPKEKFDIKRLKGSDEVYRVRIGKFRVQYVVLWDDRIIIIRKISRREGAYKNP	Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is RelB1 (Potential).
Q607A3	HRCA_METCA	Heat-inducible transcription repressor HrcA	MASFPELSERAQQLLKALVERYIGEGQPVGSRVLARDAGLSPATIRNVMADLEELGLITSPHTSAGRLPTVSGYRLFVDSLLTVKPLHQAIVDQLWLDLESRENPRDLLETASKLLSELTHMACIISMPRRETLVFQHIEFLPLSDNRVLAILVTSDQEIHNKIIHTPHKFSAAELQTAANFFNAVCGGKDMVSAREHLRAELAKERDRLSEQLLQAGEIAEQALAEGGRSRKPFLVRGETNLMDFVELADVDRLRGLFEAFRQKESIVGLLDRCLESPGVKIIIGEESGFRPLEPCSLVTASYSVDNRVMGVLGVIGPTRMKYERVIPLVDVTAKLVGAALNQRTLAPT	Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255\|HAMAP-Rule:MF_00081}.
Q608F1	SDHE_METCA	FAD assembly factor SdhE	MSQRGRLLWSCRRGMAELDRVLALYVHGAYQEADVSERQAFERLLDLQDADLWRCLTGLARPEDPALAALAAKLRALVGQAAC	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
Q60AJ7	FETP_METCA	Probable Fe(2+)-trafficking protein	MARRIICAKLGIEADGLDAPPFPGPQGQRIFEHVSKEAWQDWLKLQTMLINEHRLTPFEASARKFLEQEREKFLFGGGTSTPQGYVPPRS	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255\|HAMAP-Rule:MF_00686}.

Q5F553

FETP_NEIG1

Probable Fe(2+)-trafficking protein

MARMVFCVKLNKEAEGMKFPPLPNELGKRIFENVSQEAWAAWTRHQTMLINENRLSLADPRAREYLAQQMEQYFFGDGADAVQGYVPQ

Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.

Q5FRF2

HRCA_GLUOX

Heat-inducible transcription repressor HrcA

MMRPQPPLFRPSIPMPHGLGDREAAILREIVEEYVETGEPIGSQTLAQRLQPSLSPATIRNVMAELARAGLLFSPHVSAGRLPTEKGVRLFVDGLLQFSSLTEEDRASIDSRLDIHGRSYQDILSEASSLLSGLSSAAGLVLAPKSDATLKHIEFVALGPGRVLVILVGSDGQVENRIIETPPGVPPSALVEAGNYLNSRLGDLTLGNLRERVRAEMDASRHELDALTASVIESGLATWDADGGTLFVKGQGKLLADITEIERLTTIRMLFDHLETQETMLQLLQLADASEGVRIYIGRESGMFGMSGVSMIVAPARNEAQKIVGAIGVIGPTRLNYGRIVPVVDYTARMVGRLLG

Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.

Q5GY22

FETP_XANOR

Probable Fe(2+)-trafficking protein

MSRTVFCHYQQSDAEGLDFVPYPGELGQRIFAHIGKTAWQAWLAHQTMLINENRLSPRDPKHRAFLETELQKFLFERNADKPDGYVAPLGEE

Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.

Q5H0G1

SDHE_XANOR

FAD assembly factor SdhE

MQRHRPLGQVPLSFSARHTARWRDEMDEQTRLKKLRWRCRRGMRELDQLFGRYLDQRWAQAPDAERAVFLQLLDCEDDKLWRWFMGYEACPDVANAALIADIRALPA

An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.

Q5H188

HRCA_XANOR

Heat-inducible transcription repressor HrcA

MRASQSPMLDPRTRQLLRTLIARYIRDGEPVGSKTLAQHAGLDVSPATIRNILADLEDVGLLSSPHTSAGRVPTAHGYRVFVDSLVQMQPPGEEEVRRLRAELASGNGTQSLLGSASQMLSAMSHFVGVVSAPRREQFAFRHIDFVALDARRVLAILVFADNEVQNRVIEPRRAYEPAELERVANYLNAQFAGRALADIRACLLRELRMAKNEMEQLLAHSVDLASEALVPADADDMVMAGQTRLMGVQDLSDLDRLRELFEVFASKREILQLLERTIQAPGVRIFIGEETGMVSLEDVSLVTAPYTAHGQVLGVLGVIGPKRMAYDRLIPLVQTAADVLGAAMESPGTR

Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.

Q5HEI2

OMP7_STAAC

77 kDa membrane protein

MKFKSLITTTLALGVLASTGANFNNNEASAAAKPLDKSSSSLHHGYSKVHVPYAITVNGTSQNILSSLTFNKNQNISYKDLEDRVKSVLKSDRGISDIDLRLSKQAKYTVYFKNGTKKVIDLKAGIYTADLINTSEIKAININVDTKKQVEDKKKDKANYQVPYTITVNGTSQNILSNLTFNKNQNISYKDLEDKVKSVLESNRGITDVDLRLSKQAKYTVNFKNGTKKVIDLKSGIYTANLINSSDIKSININVDTKKHIENKAKRNYQVPYSINLNGTSTNILSNLSFSNKPWTNYKNLTSQIKSVLKHDRGISEQDLKYAKKAYYTVYFKNGGKRILQLNSKNYTANLVHAKDVKRIEITVKTGTKAKADRYVPYTIAVNGTSTPILSDLKFTGDPRVGYKDISKKVKSVLKHDRGIGERELKYAKKATYTVHFKNGTKKVININSNISQLNLLYVQDIKKIDIDVKTGTKAKADSYVPYTIAVNGTSTPILSKLKISNKQLISYKYLNDKVKSVLKSERGISDLDLKFAKQAKYTVYFKNGKKQVVNLKSDIFTPNLFSAKDIKKIDIDVKQYTKSKKNNKSNNVKFPVTINKFENIVSNEFVFYNASKITINDLSIKLKSAMANDQGITKHDIGLAERAVYKVYFKNGSSKYVDLKTEYKDERVFKATDIKKVDIELKF

Binds various plasma and ECM-proteins.

Q5HEY4

YIDD_STAAC

Putative membrane protein insertion efficiency factor

MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAFKGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5HFH8

HRCA_STAAC

Heat-inducible transcription repressor HrcA

MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFNNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLLNTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW

Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.

Q5HFZ4

CVFC_STAAC

Conserved virulence factor C

MEILRIEPTPSPNTMKVVLSYTREDKLSNTYKKVEETQPRFINQLLSIDGITSIFHVMNFLAVDKAPKADWEVILPDIKAAFSDANKVLESVNEPQIDNHFGEIKAELLTFKGIPYQIKLTSADQELREQLPQTYVDHMTQAQTAHDNIVFMRKWLDLGNRYGNIQEVMDGVLEEVLATYPESQLPVLVKHALEENHATNNYHFYRHVSLDEYHATDNWKTRLRMLNHFPKPTFEDIPLLDLALSDEKVPVRRQAIVLLGMIESKEILPYLYKGLRDKSPAVRRTAGDCISDLGYPEALPEMVLLLDDPQKIVRWRAAMFIFDEGNAEQLPALKAHINDNAFEVKLQIEMAISRIENGDEALGSVWKQMANRTI

Required for hemolysin production.

Q5HFZ8

Y1460_STAAC

DegV domain-containing protein SACOL1460

MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGASYVDQVDITSEEFINHIENDEDVKTSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQASQMVDANVTVIDSKSISFGLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIGQLNQLIKGGRISKTKGLIGNLMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEFIGDHEIKSIGVAHANVIEYVDKLKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVVLKK

May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

Q5HG29

CVFB_STAAC

Conserved virulence factor B

MALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDDDELEVGEEYSFFIYPNRSGELFATQNMPDITKDKYDFAKVLKTDRDGARIDVGLPREVLVPWEDLPKVKSLWPQPGDYLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNEVIEAKPYRVLRIGSFLLSESGYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSFLPLAHERLDDDGQVIFDLLVEYDGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQKIINIETGKIALTKKGWSRMDSKE

Contributes to the expression of virulence factors and to pathogenicity. Involved in the production of hemolysin, DNase, protease and protein A (By similarity).

Q5HGJ6

Y1252_STAAC

UPF0122 protein SACOL1252

MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE

Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255|HAMAP-Rule:MF_00245}.

Q5HHM6

EMP_STAAC

Extracellular matrix protein-binding protein emp

MKKKLLVLTMSTLFATQIMNSNHAKASVTESVDKKFVVPESGINKIIPAYDEFKNSPKVNVSNLTDNKNFVASEDKLNKIADSSAASKIVDKNFVVPESKLGNIVPEYKEINNRVNVATNNPASQQVDKHFVAKGPEVNRFITQNKVNHHFITTQTHYKKVITSYKSTHVHKHVNHAKDSINKHFIVKPSESPRYTHPSQSLIIKHHFAVPGYHAHKFVTPGHASIKINHFCVVPQINSFKVIPPYGHNSHRMHVPSFQNNTTATHQNAKVNKAYDYKYFYSYKVVKGVKKYFSFSQSNGYKIGKPSLNIKNVNYQYAVPSYSPTHYVPEFKGSLPAPRV

Adhesin that binds to the host cell extracellular matrix proteins fibronectin, fibrinogen, collagen, and vitronectin.

Q5HHS1

Y812_STAAC

DegV domain-containing protein SACOL0812

MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEIAIEEFYNKMASSQTIPTTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSYQAGEMVEGVNVHAFDSKLAAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYLIVDDLKNLQKSGRITGAQAWVGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFEDGQALYKKLQDDCPSAYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT

May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

Q5HHU1

NRDI_STAAC

Protein NrdI

MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY

Probably involved in ribonucleotide reductase function. {ECO:0000255|HAMAP-Rule:MF_00128}.

Q5HIF2

CTSR_STAAC

Transcriptional regulator CtsR

MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY

Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.

Q5HIH8

SP5G_STAAC

Putative septation protein SpoVG

MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLFVAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVVPDKNATSEDSEEA

Could be involved in septation. {ECO:0000255|HAMAP-Rule:MF_00819}.

Q5HIJ1

YABA_STAAC

Initiation-control protein YabA

MDRNEIFEKIMRLEMNVNQLSKETSELKALAVELVEENVALQLENDNLKKVLGNDEPTTIDTANSKPAKAVKKPLPSKDNLAILYGEGFHICKGELFGKHRHGEDCLFCLEVLSD

Involved in initiation control of chromosome replication. {ECO:0000255|HAMAP-Rule:MF_01159}.

Q5HJ88

ESAB_STAAC

Type VII secretion system accessory factor EsaB

MNQHVKVTFDFTNYNYGTYDLAVPAYLPIKNLIALVLDSLDISIFDVNTQIKVMTKGQLLVENDRLIDYQIADGDILKLL

Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host.

Q5HNB4

YIDD_STAEQ

Putative membrane protein insertion efficiency factor

MKKILLSLVVFYQRFISPLTPPTCRFYPTCSQYTREAIEYHGALKGLYLGVRRILKCHPLHKGGFDPVPLKKDKNSKTTHHH

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5HPV5

Y802_STAEQ

UPF0122 protein SERP0802

MGQNDLVKTLRMNYLFDFYQSLLTNKQKNYLELFYLQDYSLSEIADTFEVSRQAVYDNIRRTGDLVEDYESKLRLYQRFEKRRELYNLMKQSLNQPELLKQYITQLEELE

Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255|HAMAP-Rule:MF_00245}.

Q5HRN1

CTSR_STAEQ

Transcriptional regulator CtsR

MHNMSDIIEQYIKRLFEEADEDVVEIQRAHIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQGYYVIDGLLDKGLINEREAKMIQTIIDRETLKMDVVARDIIRANILKRLLPVINYY

Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region.

Q5HRR9

YABA_STAEQ

Initiation-control protein YabA

MNRNELFERLMKLEHHVEQLTTDMSELKDLTVELVEENVALQVENENLKRLMNKTEESVETHLDKDNYKHVKTPSPSKDNLAMLYREGFHICKGELFGKHRHGEDCLLCLNVLSD

Involved in initiation control of chromosome replication. {ECO:0000255|HAMAP-Rule:MF_01159}.

Q5HUK0

YIDD_CAMJR

Putative membrane protein insertion efficiency factor

MICLKILRFYQKFLSPLKPAACRYYPSCSEYALWQFQKKNFFLAFFSTFFRVLRCNPFFKGGFDYPRVSKNFYPINLCFKPIFLAKKQLCFLYIPYKNKSFYLIKIIFKRTNQ

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5JDM5

BRIX_THEKO

Probable Brix domain-containing ribosomal biogenesis protein

MMLITTSHRPTRRTRSFGHDLEKVFPNSLYLTRGKKTIQDLLMEAYDRGYERLLIINVWKGNPLKMTFIKVDPEDWGYIGYLYLHGIKLQREIGFRNIPPIREEMPFVVTTAKRVGIDHTAFAQVFAELTGGKFVPRGNKSLQTIADKNNTDVIGVIENYPRGMAVNFYRFDITRERPVGPLILVKIWIMEDGRRWDYKEALGIKPKE

Probably involved in the biogenesis of the ribosome. {ECO:0000255|HAMAP-Rule:MF_00699}.

Q5JDU6

Y1752_THEKO

Putative antitoxin TK1752

MGKTITIADDVYYELVKMKGKKSFSELLRELIGKKKKGNLDVLMIAFGTRTPEEVEELKKELKEVEEWMDSWTPASL

Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. {ECO:0000255|HAMAP-Rule:MF_00794}.

Q5KVY7

YIDD_GEOKA

Putative membrane protein insertion efficiency factor

MGQWLIWCIRFYQRFLSPLKPPTCRFYPTCSNYGIEAIRRFGAIKGGWLTAKRILKCHPFHPGGFDPVPESSEHAKRNKIT

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5L0Q0

Y1195_GEOKA

UPF0122 protein GK1195

MLEKTMRMNYLYDFYQALLTPKQRNYMALYYLDDYSLGEIAEQYEVSRQAVYDNIRRTEAMLEQYEEKLGLLRKYERRRQIIERLKDYISRRYGADAELAALVRELDELD

Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255|HAMAP-Rule:MF_00245}.

Q5L300

LUTA_GEOKA

Lactate utilization protein A

MKVSLFVTCLIDLFYTEVGKATVELLERLGCKVDFPEAQTCCGQPAYNSGYVKEAKEAMKQMMRAFADADYVVTPSGSCAAMLKEYPHIFHGDPEWEAEAKRLAAKTYELTQFLVDVLKVEDVGASLHGRATYHTSCHMTRLLGVKDAPLRLLEHVKGLELVPLPNAHQCCGFGGTFSVKMGPISEQMVDEKIGHIEEAEADYLIGADCGCLLNIGGRIARLGKPIRVMHIAEVLNARN

Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. {ECO:0000255|HAMAP-Rule:MF_02105}.

Q5L302

LUTC_GEOKA

Lactate utilization protein C

MTRGAIHNRDAFLEHIAHRLGRAPRLSGVSRPQWSNQPQWKVLAGYSQDDLLNVLQKQCGLIHTDYIETTSAELAGALRRQVAAYGGGPVIVPDDPRFAEYGLSALLRDEWPAEQTTVHIWNPALGRQNIDAAEQANVGIAFSDITLAESGTVVLFSRNEQGRAIHFLPKTYIAIVPKSTVVPRMTQAAAVIHEQIEKGGLVPSCINFITGPSNSADIEMNLVVGVHGPMKAAYIVVTDR

Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. {ECO:0000255|HAMAP-Rule:MF_02104}.

Q5L3V1

SP5G_GEOKA

Putative septation protein SpoVG

MEVTDVRLRRVNTEGRMKAIASITLDNEFVVHDIRVIDGNNGLFVAMPSKRTPDGEFRDIAHPINSATRGKIQEAILAEYHRLGKLEEELEEAGAS

Could be involved in septation. {ECO:0000255|HAMAP-Rule:MF_00819}.

Q5L6W5

YIDD_CHLAB

Putative membrane protein insertion efficiency factor

MSFKQLLYNLPTHLCCGLIHLYRWTISPLLGSPCRFFPSCSQYALQALKHHKCIRGLWLTIKRIGKCGPWHPGGIDLVPMTTLEEALDVSQVTNDDDSGDSHA

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5LJ21

YIDD_BACFN

Putative membrane protein insertion efficiency factor

MKRLLSYILLLPIYFYRACISPMTPPSCRFTPTCSQYAIEAIKKHGPFKGLYLAVRRILRCHPWGGSGYDPVP

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5M027

Y888_STRT1

UPF0122 protein str0888

MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEEFGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDDIMEKYADDSYLQEQIAILSSIDNRD

Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255|HAMAP-Rule:MF_00245}.

Q5M1H7

YIDD_STRT1

Putative membrane protein insertion efficiency factor

MMKKFLIALVKAYQRWISPLFPLSCRFCPTCSVYMIQAIEKHGLKGVLMGIARILRCHPLSETGDDPVPDYFSLKRKKTPLDN

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5M1U0

HRCA_STRT1

Heat-inducible transcription repressor HrcA

MITQRQNAILNLIVEMFTRTHEPVCSKALQDSIDSSSATIRNDMAKLEKMGYLEKAHISSGRMPSRAGFQYFVANSLNLDTIDEQDVYQVVKAFDFEAFKLEDILDAAAKLLAEMTGCTAVIQDVEPTKQRLTGFEIVQLSNHDALAVLTLDESKPVTVQFAIPKNFLSSDLEIFHKLVQGRFLGNTVLDIHYRLRTETPQIVQKYFKITDNVLDLFDYIFSHLFKELIFIEGKVASLAYADLKTYQFLDNPQHVALALRSAISDDEVTKISVAESTEEALENVTVMSHKFLIPYRGTALMHVIGPIEMDYRRMVSLVNVISRVLVMKLTDYYRYLNSNHYEVFLSRNVLKNIERGECLD

Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.

Q5M4P2

Y888_STRT2

UPF0122 protein stu0888

MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEEFGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDDIMEKYADDSYLQEQIAILSSIDNRD

Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255|HAMAP-Rule:MF_00245}.

Q5M619

YIDD_STRT2

Putative membrane protein insertion efficiency factor

MMKKFLIALVKAYQRWISPLFPLSCRFCPTCSVYMIQAIEKHGLKGVLMGIARILRCHPLSETGDDPVPDYFSLKRKKTPLDN

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5MGP9

DFP2_LONON

Defense protein 2 (DFP-2)

TGSGKYNILHNDNHNLDLTGKFLECSRSNPNLSDYNKYSAILDYLYKDKLSASLGVAHSGLLDRTDLSALGKVNLLNDKNTRLDLFGGLTKSMSPKFDSGLKPNFGLQLESSF

Has antibacterial activity against both Gram-positive and Gram-negative bacteria.

Q5MZ58

YIDD_SYNP6

Putative membrane protein insertion efficiency factor

MKLLLLALIQFYRRWISPLTPASCRFYPTCSQYGLEAIDRFGPLKGSWLTLCRILRCHPFHPGGYDPVPPLPSCSCGKSPCD

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5N3M2

HRCA_SYNP6

Heat-inducible transcription repressor HrcA

MLVSRLTARQQTILSATVRHYVRTAEPVGSKALAEQYGLSVSAATIRNAMGVLERAGLLYQPHTSAGRVPSEGGYRLYVDQLMEPDRALQRQTEQQLSQQLPDRRQSLEALLRGAAQILASLSGYLSLITFPLGLEFQVRHLQLVAIAPHQVLLIVVNDSYETQSALLTLPELDRDLEADQLDRQLLLLSNFLNQELQGRSLQALANLDWPVLGSELQSLAGILQQGLQDLEKRWQPTPATSLLVCGLADLLRQPEFNELQQVQALLELLEGEQTQLLPLMLADPAADQVRVRIGSELPLAPIRSCSLVSAFYCREQQPVGSVSLIGPTRMLYENAVAAVEATASYLSEAIAS

Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.

Q5NDN1

VSR_PNLV

Putative suppressor of silencing

MQNVNIPVGICNNRIVFRSLGFALSENNLTIEVLSRPIESLGRVLLFLYLYPSFAADYAQRYYGATWNQAYDISVRSLAFLLPFLFSPAVEWAVGPVFKSFVPLTELLKWSLAVGYYPTFPGSRQQLPSVPYDVNYGVQSTKAATVKLLRRAMLDDCIQSKTRLEAMLERGPDTFRNVLKAHISRIDRFTSSSGWHVADDYHMDLVLDISSGISRPSVHDNISFIQRSMRRISDILYDLCVPAHFLDLWRFTGLQCFWIDPNLGKF

Suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.

Q5NFS4

SDHE_FRATT

FAD assembly factor SdhE

MLIKNNDLIFSSVDKIKYSARRGMLELDIILAPYLNNCYMHEDLANKKLFVEFLTSEDSDMFDWLFKGVTPPQRYQQLIDKIIKEKKKFNQTKLK

An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.

Q5NHJ8

FETP_FRATT

Probable Fe(2+)-trafficking protein

MTKVFCKKYHQELDAIPFQPLPGELGKKIHNEISNKAWQAWLAHQTILINEYRLNLIEPKAKEFLKEEMHKFLFEGKEEKPEQFSEI

Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.

Q5NI55

YIDD_FRATT

Putative membrane protein insertion efficiency factor

MLINLYRYCISPFIPARCRYYPTCSEYALEALKTHGILKGLYLTTRRLLRCHPLSKRDYYDLVPCKNKKG

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5NVD7

ELMD1_PONAB

ELMO domain-containing protein 1

MKHFLRMLIQVCLYFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIEDIMELKKINPDVNPQLGISLQACLLQIVGYRNLIADVEKLRREPYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATAAQQVLSDSLHPKCSKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM

Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family.

Q5P4P3

YIDD_AROAE

Putative membrane protein insertion efficiency factor

MKALVLGLLRVYRYAISPMLGRNCRFHPCCSEYAQEAVERHGAMRGGWLALKRVGRCHPFHPGGYDPVP

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5PC89

GLGS_SALPA

Surface composition regulator

MNNNNVYSLNNFDFLARSFARMQAEGRPVDIQAVTGNMDEEHRDWFCKRYALYCQQATQAKKLELEH

Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides. {ECO:0000255|HAMAP-Rule:MF_00525}.

Q5PEK1

SYDP_SALPA

Protein Syd

MDELTAQALKAFTTRYCDAWQEKHGSWPLSEELYGVPSPCIISSTRDAVYWQPQPFEGEENVNAVERAFDIMVQPALHAFYTTQFAGDMPAQFADEKLTLLQTWSQDDFRRVQENLIGHLVTQKRLKLPPTLFIATQENELEVISVCNLSGEVIKETLGTRNRTVLAATLAEFLTQLNPLL

Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. {ECO:0000255|HAMAP-Rule:MF_01104}.

Q5PF04

NRDI_SALPA

Protein NrdI

MSALVYFSSSSENTHRFMQRLGLPATRIPLNERERIRVDEPYILVVPSYGGGGMAGAVPRQVIRFLNDEHNRARIRGVIASGNRNFGDAWGCAGDVIAQKYGVPWLYRFELMGTQRDIDNVRRGVNEFWQQLPRSA

Probably involved in ribonucleotide reductase function. {ECO:0000255|HAMAP-Rule:MF_00128}.

Q5PGA1

CBPM_SALPA

Chaperone modulatory protein CbpM

MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNTDWQFDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRLLLQRLSRFISHP

Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ. {ECO:0000255|HAMAP-Rule:MF_01155}.

Q5PKF1

FDHE_SALPA

Protein FdhE

MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKHWQKLLHSLIAELKPEMNGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFIWAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIDTTQGLRYLHCNLCETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAVADDLASLVLDARMEQEGFARSSINPFLFPGEGE

Necessary for formate dehydrogenase activity. {ECO:0000255|HAMAP-Rule:MF_00611}.

Q5PKU3

YIDD_SALPA

Putative membrane protein insertion efficiency factor

MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5PPV3

MORN3_XENLA

MORN repeat-containing protein 3

MPLVKAPKKAEPIWKEWDAKAQKAGLRHSVYSVNGDEYTGEWLNNLRHGKGTYMWKRRKSIYEGDWKCGERSGFGTYSVQDSNTGEYIKVYSGYWDNDKKHGYGTHFYSAKEYYEGEWKCGKRCGWGRMYFANGDIYEGEWLEDKHSGQGMLCLANENRYEGSWKDGKKHGPGKFYYLNKGQLYEGVWVEDIPKCGTMVDFGRTEAPYPTKYPLPEVKVADPEGVLKEAQQPLFGEHE

Assembles a suppression complex (suppresome) by tethering SIRT1 and MDM2 to regulate composite modifications of p53/TP53. Confers both deacetylation-mediated functional inactivation, by SIRT1, and ubiquitination-dependent degradation, by MDM2, of p53/TP53, promoting a proliferative and cell survival behaviors (By similarity). May play a role in the regulation of spermatogenesis (By similarity).

Q5PQ44

CF299_XENLA

Cilia- and flagella-associated protein 299

MEQSEAGSAADSIITQFNTYEDFLDSQITALDLHYLEDEELARQLVELGYRGSGEVLKRDEFEARKAAAEASRLSQRTQQKTLSSAGKDPKDNFLKALAMREEANRNGKMTSVIFIRDKNAHGQEVSGYIDFAHRLKTEDFEVYFSGKKKLLPRPTDLSFYNWESHVSTSNPSPNYQVIAETSSGLLFKNKRDRKILNVDPKASPGDNSTRTSIQTDIYIQAVIYDHITRRKS

May be involved in spermatogenesis.

Q5QW09

SYDP_IDILO

Protein Syd

MKTLEESIDALMTRYKENVPVRYTEYVEEWNSPIYGTVIDENTVEWTPCRQPEALNFDDLESALEMSFHQSIKTLFGRWYAGDLALDYQGHTISLLQTQSAEDGERLLENITGHILMKRRLKQPETVFIGLGSEDDGLLVTIDNQSGAVGLEWVGKEQHDVLSDSLAAWLDNCQPQVETDKNS

Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. {ECO:0000255|HAMAP-Rule:MF_01104}.

Q5QY58

FETP_IDILO

Probable Fe(2+)-trafficking protein

MSRTVFCEHFQKEAEGLDFQLYPGELGERIFNHISKDAWAEWQKKQTMLINEKRLNMMDPTDREFLEKQMTAFLFEGKAPEIEGYTPPES

Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.

Q5R0Z7

SDHE_IDILO

FAD assembly factor SdhE

MLPLKQSEEALKDKRRLRWACRRGMLELDVLFEPFVDQAYDELSEEQKAVFRRLITCDDPDLFAWFMGHQKCEDEELAEMIRFMLSRVKV

An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.

Q5R796

FBX36_PONAB

F-box only protein 36

MASWLPETLFETVGQGPPPSKDYYQLLVTRSQVIYRWWKISLRSEYRSTKPGEAKETHEDFLENSHLQGQTALIFGARILDYVINLCKGKFDFLERLSDDLLLNIISYLDLEDIARLCQTSHRFAKLCMSDKLWEQIVQSTCDTITPDVRALAEDTGWRQLFFTNKLQLQRQLRKRKQKYGNLREKQP

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Q5R8D4

AVPI1_PONAB

Arginine vasopressin-induced protein 1 (AVP-induced protein 1)

MGTPASVVSEPPPWQAPTEARGRKQASANIFQDAELLQIQGLFQRSGDQLAEERAQIIWECAGDHHVAEALKRLRRKRPPRQKPLGHSLHHCSRLRILEPHSPLADPQSATETASTEQYLHSRRKSARIRRNWKKPGPTSYLHQIRH

May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.

Q5RBE4

DEPP_PONAB

Protein DEPP

MRSRLLLSVAHLPTIRETTEEMLLGGPGQEPPPSPSLDDYVRSISRLAQPTSVLDKATAQGQPRPPHRPAQACRKGRPAVSLRDITARFSGQQPTLPMADTVDPLDWLFGESQEKQPSQRDLPRRTGPSAGLWGPHRQMDSSKPMGAPRGRLCEARMPGHSLARPPQDGQQSSDLRSWTFGQSAQAMASRHRPRPSSVLRTLYSHLPVIHEL

May play a role in autophagy.

Q5RCY5

ASTE1_PONAB

Protein asteroid homolog 1

MGIRGLMSFVEDHSNEFFTDLKLRDTKIVIDGYALFHRLCFSSNLDLRYGGDYDSFADVVQKFFESLFACNICPYVVLDGGCDISDKKLTTLKDRAREKIQMAHSLSVGGSGYVCPLLIREVFIQVLIKLRVCFVQCFSEADRDIMTLANHWNCPVLSSDSDFCIFDLKTGFCPLNSFQWRNMDTIKGTQNYIPAKCFSLDAFCHHFSNMNKALLPLFAVLCGNDHVNLPIMETFLSKARLPLGATSSKGRRHHRILGLLNWLSHFANPTEALDNVLKYLPKKDRENVKELLCCSMEEYQQSQVKLQDFFQCGTYVCPDALNLGLPEWVLVALAKGQLSPFISDALVLRRTILPTQVENMQQPNAHRISQPIRQIIYGLLLNASPHLDKTSWNALPPQPLAFSEVERINKNIRTSIIDAVELAKDHSDLSRLTELSLRRRQMLLLETLKVKQTILEPIPTSLKLPIAVSCYWLQHTETKAKLHHLQSLLLTMLVGPLIAIINSPGKEELQEDGAKMLYAEFQRVKAQTRLGTRLDLDTAHIFCQWQSCLQMGMYLNQLLPTPLPEPDLTRLYSGSLVHGLCQQLLASTSVESLLSICPEAKQLYEYLFNATRSYAPAEIFLPKGRSNSKKKRQKKQNTSCSKNRGRTTAHTKCWYEGNNRFGLLMVENLEEHSEASNIE

Possible role in EGF receptor signaling.

Q5RD58

CL004_PONAB

Protein C12orf4 homolog

MKKNRERFCNREREFVYKFKVGSQCLELRVPLRFPVQENASHLHGRLMLLHSLPCFIEKDLKEALTQFIEEESLSDYDRDAEASLEAVKSGEVDLHQLASTWAKAYAETTLEHARPEEPSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELIGERDVELKKLRERQGIEMEKVMQELGKSLTDQDVNSLAAQHFESQQDLENKWSNELKQSTAIQKQEYQEWVIKLHQDLKNPNNSSLSEEIKVQPSQFRESVEAIGRIYEEQRKLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRNHRSGVKLHRLQTALSLYSTSLCGLVLLVDNRINSYSGIKRDFATVCQECTDFHFPRIEEQLEVVQQVVLYARTQRRSKLKESLDSGNQNGGNDDKTKNAERNYLNVLPGEFYITRHSNLSEIHVAFHLCVDDHVKSGNITARDPAIMGLRNILKVCCTHDITTISIPLLLVHDMSEEMTIPWCLRRAELVFKCVKGFMMEMASWDGGISRTVQFLVPQSISEEMFYQLSNMLPQIFRVSSTLTLTSKH

Plays a role in mast cell degranulation.

Q5REM2

L10K_PONAB

Leydig cell tumor 10 kDa protein homolog

MAQGQRKFQARKPAKSKTAATASEKNRGPRKGGRVIAPKKARVVQQQKLKKNLEVGIRKKIEHDVVMKASSSLPKRLALLKAPAKKKGAAAATSSKTPS

May have a potential role in hypercalcemia of malignancy.

Q5RFN8

TM101_PONAB

Transmembrane protein 101

MASKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMIQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHNTRRVEFWNQMKLLGESVGIFGTAVILATDG

May activate NF-kappa-B signaling pathways.

Q5SL49

YIDD_THET8

Putative membrane protein insertion efficiency factor

MREVLILLIRFYRRFLSPLKPRTCRFHPTCSAYALEALERHGAFWGSYLAVRRVLRCHPWNPGGLDPVPVLFPPGKVRGGAE

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5UQD7

SUI1_MIMIV

Protein translation factor SUI1 homolog

MLNRIIYDPFNDGLDTEQHFEKIHIKTKQRTKTKSITIIENIPEKIDLKLFLKKLKYTFHCSGSIQQNYDDDSKFIQLSGDHRELVKNFLIKNSIVKESNIVMHGY

Additional factor that functions in concert with eIF-2 and the initiator tRNA in directing the ribosome to the proper start site of translation.

Q5WF19

YIDD_ALKCK

Putative membrane protein insertion efficiency factor

MRKLLIQIIRLYQRFISPLTPPSCRFYPTCSAYGIEAIETHGAIKGSYLAIKRILKCHPFHPGGVDPVPECQHTKHKKTP

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5WFN0

Y2295_ALKCK

UPF0122 protein ABC2295

MLDKTLRMNYLFDFYHSLLTEKQRNYMSYYYLDDLSLGEIADEYDVSRQAVYDNIRRTEAMLEEYEQKLRLLEKFETRRSLLAELRKAIASDQAVEACNSLIDRIEKLD

Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255|HAMAP-Rule:MF_00245}.

Q5WJD9

LUTC_ALKCK

Lactate utilization protein C

MIKNRDSFLDHVANQLGRPRQTEGVLRPNYRVSPQFEVLKDASKDELVTVLKEQCVAIHTDFKQVESGQLETALDETIDMYGAKSVIAWDDRRFHEFGLGSFLTRPSVSLWDNRDSKRSIEQAEIADVGITFSDITLAESGTVTLFSSNGKGRSVSLLPRYYIAIIPKSTLVARMTQAARHIRQLTGEGRLPSCINFISGPSNSADIEMSLVVGVHGPLKACYIVVDDK

Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. {ECO:0000255|HAMAP-Rule:MF_02104}.

Q5WJE1

LUTA_ALKCK

Lactate utilization protein A

MNVSLFVTCLADIFYPGVGKDTVEVLERHGCNVKFPENQICCGQPAFNSGYHEDTKKAAKHTIETFADADYVVLPSGSCAAMLLEYKELFADDPEWEKRAEELASKTYELTQFLVRVLKVEDIGAVCHKKATYHTSCHMSRLLRETEAPFSLLEQVKGLELAPLANKESCCGFGGTFSVKMPAISEQMVEEKVGHIEATGADLLIGADCGCLMNIGGRIERNGKTIEVKHIAQVLNSKE

Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. {ECO:0000255|HAMAP-Rule:MF_02105}.

Q5WQ00

REPA1_BUCCC

Probable replication-associated protein repA1

MFKRKKYVDNPYPKFVQPKNHKKRPAFIRYAMRCAAQTDVARNELYYTNPLKNPITGCVLHRKRRLNEHRARALRAVVQAMLYYFNIASMLVMASVEKLSDVCGLSTYSSAGNKSITRASRLITQFMEPMGLISCEKIWDKILGMYIPKIIYLKPLFFMLFDISKIRLKRVRIKQLEWINSQLKKKGEYPITLLEIEKQAKEKHIHSALLFRKSKYIIKKQKNKAKKFLELDEKYAKSYILNNLVKKYSTKELCKLGLTKLKRKVNCEYFRLKKLAQLPVV

This protein is essential for plasmid replication it is involved in copy control functions.

Q5WSE8

YIDD_LEGPL

Putative membrane protein insertion efficiency factor

MGKINLMLRQIVCLPIKMYQYFISPLITPCCRYYPSCSEYADSAIKHYGVIKGLLMALNRLSRCHPWSKGGYDPLFPNDKN

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5WVC4

FETP_LEGPL

Probable Fe(2+)-trafficking protein

MSRTVFCCKLKQEAEGLEKQPFPGELGKKVFNEVSKQAWNMWLSHQTMLINEYRLNLIEARAREFLKEEMQKYFFGEGSDKPSGYKEIK

Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.

Q5WWK6

SDHE_LEGPL

FAD assembly factor SdhE

MDNREKSRLLWKCRRGMLELDLVLQKFIANEIDRLTENQLKAFDNLLTHNDPNLYAWLMGHEEPEKELLEIVSFIRNCD

An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.

Q5X0M1

YIDD_LEGPA

Putative membrane protein insertion efficiency factor

MGKISLMLRQIVCLPIKMYQYFISPLITPCCRYYPSCSEYADSAIKHYGVIKGLLMALNRLSRCHPWSKGGYDPLFPNDKN

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5X3X9

FETP_LEGPA

Probable Fe(2+)-trafficking protein

MSRTVFCCKLKQEAEGLEKQPFPGELGKKVFNEVSKQAWNMWLSHQTMLINEYRLNLIEARAREFLKEEMQKYFFGEGSEKPSGYKEIK

Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.

Q5X4Y4

SDHE_LEGPA

FAD assembly factor SdhE

MDNREKSRLLWKCRRGMLELDLLLQKFIANEIDRLTENQLKAFDNLLTHNDPSLYAWLMGHEEPEKELLEIVSFIRNCD

An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.

Q5X9X0

Y1658_STRP6

DegV domain-containing protein M6_Spy1658

MTFTIMTDSTADLNQTWAEDHDIVLIGLTILCDGEVYETVGPNRISSDYLLKKMKAGSHPQTSQINVGEFEKVFREHARNNKALLYLAFSSVLSGTYQSALMARDLVREDYPDAVIEIVDTLAAAGGEGYLTILAAEARDSGKNLLETKDIVEAVIPRLRTYFLVDDLFHLMRGGRLSKGSAFLGSLASIKPLLWIDEEGKLVPIAKIRGRQKAIKEMVAQVEKDIADSTVIVSYTSDQGSAEKLREELLAHENISDVLMMPLGPVISAHVGPNTLAVFVIGQNSR

May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

Q5XAD4

HRCA_STRP6

Heat-inducible transcription repressor HrcA

MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDMAKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKTFDFEAFKLEDMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQFAIPRNFLTRDLIAFKAIVEERLLDSSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFDYVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADSQEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYRYLNSNHYEVH

Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.

Q5XAI8

Y1140_STRP6

DegV domain-containing protein M6_Spy1440

MTWKIVTDSGCDLRSLTRQSKELRFERVPLTLQIGTEIFRDDDGLDIDNMMTTMYQSSKATTSSCPSPEAFLQAYRGADNVIVMTITGTLSGSHNSARLAKNELLEENPNVNIHLIDSLSAGGEMDLLVLELERLINLGLSFEEVVKQITAYQQKTRLIFVLAKVDNLVKNGRLSKLVGKVIGLLNIRMVGKASNKGTLELLQKARGQKKAVSALIEEIQKEGYVGGKVYIAHAQNPKICEQISEKIKSLYPDAVIQTGRTSGLCSFYAEDGGLLMGYEI

May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

Q5XC23

Y905_STRP6

UPF0122 protein M6_Spy0905

MNTMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEKISILTSIDNRE

Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. {ECO:0000255|HAMAP-Rule:MF_00245}.

Q5XCN8

Y690_STRP6

DegV domain-containing protein M6_Spy0690

MKLAVITDSTATLPIDLKQDKAIFSLDIPVIIDDETYFEGRNLSIDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDRTTAFIMVDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPRL

May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.

Q5XDK5

NRDI_STRP6

Protein NrdI

MAELIIVYFSSKSNNTHRFVQKLGLPAQRIPVDNRPLEVSTHYLLIVPTYAAGGSDAKGAVPKQVIRFLNNPNNRKHCKGVISSGNTNFGDTFALAGPIISQKLQVPLLHQFELLGTATDVKKVQAIFARLKHHTHDKQKQTNNLITERTHPCHKPMRHTSH

Probably involved in ribonucleotide reductase function. {ECO:0000255|HAMAP-Rule:MF_00128}.

Q5XDL8

YABA_STRP6

Initiation-control protein YabA

MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQSLVEENTILRLENTKLRERLSHLEHETVAKNPSKQRKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRELLDRK

Involved in initiation control of chromosome replication. {ECO:0000255|HAMAP-Rule:MF_01159}.

Q5XDP1

YIDD_STRP6

Putative membrane protein insertion efficiency factor

MKKLLIVSVKAYQKYISPLSPPSCRYKPTCSAYMLTAIEKHGTKGILMGIARILRCHPFVAGGVDPVPEDFSLMRNKNTSKNAEKA

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5YMR8

YIDD_NOCFA

Putative membrane protein insertion efficiency factor

MRSAAAALHRLPARALIFLIELYRTYVSPTRMPVCRFTPTCSEYAVTALRTRGLVVGLGLTAVRLAKCAPWHPGGWDPVPQRRPRRRDAAAADAAMSAPHACKGSPHAVVGDTNDGST

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5YZX1

HRCA_NOCFA

Heat-inducible transcription repressor HrcA

MGPMSSSTEDRRFEVLRAIVADYVATKEPIGSKTLVERHNLGVSSATVRNDMAVLEAEGYITQPHTSSGRIPTDKGYRQFVDRISEVKPLSAAERRAILQFLESGVDLDDVLRRGVRLLAQLTRQVAVVQYPTVSASTVRHIEVVALNPARLLLVVITDTGRVDQRIVELGAVVDDDDLSALRALLGAAMDGKRLAAASAAVAELPESAPQQLRDVLIRVSTVLVETLVEHPEERLVLGGTANLTRNAADFGLPGSLRQVLEALEEQVVVLKLLAAAQQPGTVTVRIGEETQVEEMRSASVVTTGYGVSGSVLGGMGVLGPTRMDYPGTIASVATVARYIGEVLAER

Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.

Q5ZJ37

RABEK_CHICK

Rab9 effector protein with kelch motifs

MGPRVLPLLEPGCRPQAGKWYRMAPRGEWPRGRVGHGCLFVPGGSGRVLLLGGADPAGAFADAHFVELGAHLWAPAAWSGLRPRYEHATFLSACRPPRLWVFGGAHRAGNRSCVQVLDPEIGTWESPEVTGIPPLPRTFHTSSAAIGDCLYVFGGGDKGAEPVKDQQLHVFDTVALAWTQPDTHGDPPSPRHGHVVVAVGTKLFIHGGLAGDIFYNDLFCIDTTDMKWVKIAATGDVPGGRASHSSAVFKDHLYIFGGIGPDGTLDTTYKYHIEEQQWTLLQFDSPLPAGRLDHAMCVIPWRVGKNGDAAAVSKEDKAEPTASAGDRAGHLCRGQDKKACTEDTMMHLLLIFGGMDTQAEIYRDCIVSLIE

Rab9 effector required for endosome to trans-Golgi network (TGN) transport.

Q5ZL79

NOL11_CHICK

Nucleolar protein 11

MAALCEAFTLCGLGPAGGVGLGSGLLALEPGADPDHVLLTDRGRTTTLFKVSDQKPLGCWSVKHGQIITCPVVCNFETHEYIAVHDNKVLRIWKDEDVNLDKVFKATLSAEVYRIHSLPHAEPLVLFKGGGVRTLDVLLEAPQQEIENVISDEVIKWSEAFLESRQPVLIFVTEKDGDFFVYVQKPKMRSLHKYKLEQQELCNPLSFTAYIKKQIITLLCLYSSDSVYKVLIPLQQSSEEEEQTSSKSLLLNLSISGSVLKGTSFVVLDKDHVAVLGSLAASGEESKECLTIWNTKFQTLQASKELPLGTSGQLWCYGEKFFFTHGKVLTVVIYKCETSSLAAAVGKLKDSQTSDLSSFVNWNTLGDEELLVSLQSQQSVALKSESKMTLRSKKSAVANIQPDTSTVGQFLLSIKDASTAAVEDQLRQLLSKAQMPDFQATIGCIISALINRCKTDPKFYPRNFLVQMIQKGELSYSLCPDLMAVALEKKDVHLLQICLQRFPDIPEEITYACLKVFLSISDDYLERTDVNLESVISYIDIEPNNKEVKTEVVENGFNTELEEDGCDVTGMKETHMMDSVEFCPVGPQKAALLNAVLHSAYSETFLLPHLKDLPAQQAVLFLRYLHYLYVKCSEKINTTLPGILSPTISQIMDWMCLLLDAHFTVMVMLPEAKGLLSSMHRFVRAQVRLYSELNKIEGSLQELQRIKCQKHSQAYSIEVLELI

Ribosome biogenesis factor. May be required for both optimal rDNA transcription and pre-rRNA processing (By similarity).

Q5ZR80

YIDD_LEGPH

Putative membrane protein insertion efficiency factor

MGKISLMLRQIVCLPIKMYQYFISPLITPCCRYYPSCSEYADSAIKHYGVIKGLLMALNRLSRCHPWSKGGYDPLFPNDKN

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q5ZU80

FETP_LEGPH

Probable Fe(2+)-trafficking protein

MSRTVFCCKLKQEAEGLEKQPFPGELGKKVFNEVSKQAWNMWLSHQTMLINEYRLNLIEARAREFLKEEMQKYFFGEGSEKPSGYKEIK

Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.

Q60228

RELX_ECOLX

Putative RelE-like toxin protein

MRYQVKFREDALKEWQKLDKAIQQQFAKKLKKCCDNPHIPSAKLRGIKDCYKIKLRASGFRLVYQVIDEQLIIAVVAVGKRERSDVYNLASERMR

Toxic component of a type II toxin-antitoxin (TA) system.

Q60265

Y3531_METJA

Putative antitoxin MJECL31

MSEIIEVIYEDGVLKPLKPLKIKGKKRLKIKIVNDDVEEFLKSMIIKKCKDIDYKKLKEAYYESF

Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.

Q602M7

YIDD_METCA

Putative membrane protein insertion efficiency factor

MQRLLITLIRLYQYLLSPWLGHHCRFFPTCSNYAMDAIGRFGAMRGAYLTIRRLMRCHPWHPGGIDPVPEKLGKQ

Could be involved in insertion of integral membrane proteins into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386}.

Q60373

RELB1_METJA

Putative antitoxin RelB1

MLNINKEIAQIETELNELKKLRDEISERIEKLEIKLLKLKALAIPEEEFEEDYEEIIEDVKKSLDKKETVPAEEALKELGLL

Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is RelE1 (Potential).

Q60374

RELE1_METJA

Putative toxin RelE1

MKFNVEIHKRVLKDLKDLPPSNLKKFKELIETLKTNPIPKEKFDIKRLKGSDEVYRVRIGKFRVQYVVLWDDRIIIIRKISRREGAYKNP

Toxic component of a type II toxin-antitoxin (TA) system. Its cognate antitoxin is RelB1 (Potential).

Q607A3

HRCA_METCA

Heat-inducible transcription repressor HrcA

MASFPELSERAQQLLKALVERYIGEGQPVGSRVLARDAGLSPATIRNVMADLEELGLITSPHTSAGRLPTVSGYRLFVDSLLTVKPLHQAIVDQLWLDLESRENPRDLLETASKLLSELTHMACIISMPRRETLVFQHIEFLPLSDNRVLAILVTSDQEIHNKIIHTPHKFSAAELQTAANFFNAVCGGKDMVSAREHLRAELAKERDRLSEQLLQAGEIAEQALAEGGRSRKPFLVRGETNLMDFVELADVDRLRGLFEAFRQKESIVGLLDRCLESPGVKIIIGEESGFRPLEPCSLVTASYSVDNRVMGVLGVIGPTRMKYERVIPLVDVTAKLVGAALNQRTLAPT

Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. {ECO:0000255|HAMAP-Rule:MF_00081}.

Q608F1

SDHE_METCA

FAD assembly factor SdhE

MSQRGRLLWSCRRGMAELDRVLALYVHGAYQEADVSERQAFERLLDLQDADLWRCLTGLARPEDPALAALAAKLRALVGQAAC

An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.

Q60AJ7

FETP_METCA

Probable Fe(2+)-trafficking protein

MARRIICAKLGIEADGLDAPPFPGPQGQRIFEHVSKEAWQDWLKLQTMLINEHRLTPFEASARKFLEQEREKFLFGGGTSTPQGYVPPRS

Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. {ECO:0000255|HAMAP-Rule:MF_00686}.